# HG changeset patch
# User artbio
# Date 1567413560 14400
# Node ID 569334568afafc90b696ff41932603cd98ed5ca0
# Parent  8e17c31c536a27dd72c916e17eeddf107faa291e
"planemo upload for repository https://github.com/ARTbio/tools-artbio/tree/master/tools/gsc_high_dimension_visualization commit 1b98c85982a2a9f9df4b318f672b9b68cff66a93"

diff -r 8e17c31c536a -r 569334568afa high_dim_visu.R
--- a/high_dim_visu.R	Thu Jul 11 12:31:28 2019 -0400
+++ b/high_dim_visu.R	Mon Sep 02 04:39:20 2019 -0400
@@ -2,7 +2,6 @@
 options( show.error.messages=F,
        error = function () { cat( geterrmessage(), file=stderr() ); q( "no", 1, F ) } )
 loc <- Sys.setlocale("LC_MESSAGES", "en_US.UTF-8")
-requiredPackages = c('optparse', 'Rtsne', 'ggplot2', 'ggfortify')
 warnings()
 library(optparse)
 library(FactoMineR)
@@ -12,6 +11,7 @@
 library(ggfortify)
 library(RColorBrewer)
 library(ClusterR)
+library(data.table)
 
 # Arguments
 option_list = list(
@@ -161,9 +161,9 @@
   ),
   make_option(
     "--HCPC_metric",
-    default = 'euclidian',
+    default = 'euclidean',
     type = 'character',
-    help = "Metric to be used for calculating dissimilarities between observations, available 'euclidian' or 'manhattan' [default : '%default' ]"
+    help = "Metric to be used for calculating dissimilarities between observations, available 'euclidean' or 'manhattan' [default : '%default' ]"
   ),
   make_option(
     "--HCPC_method",
@@ -209,7 +209,7 @@
   ),
   make_option(
     "--HCPC_kk",
-    default = -1,
+    default = Inf,
     type = 'numeric',
     help = "The maximum number of iterations for the consolidation [default :'%default']"
   ),
@@ -220,10 +220,16 @@
     help = "Output result of HCPC clustering : two column table (cell identifiers and clusters) [default :'%default']"
   ),
   make_option(
-    "--mutual_info",
+    "--HCPC_mutual_info",
     default = "",
     type = "character",
     help = "Output file of external validation of HCPC clustering with factor levels [default :'%default']"
+  ),
+  make_option(
+    "--HCPC_cluster_description",
+    default = "",
+    type = "character",
+    help = "Output file with variables most contributing to clustering [default :'%default']"
   )
 )
 
@@ -436,7 +442,7 @@
        col = factorColors$color, pch = 16, bty = 'n', xjust = 1, cex=0.7)
     
     ## Normalized Mutual Information
-    sink(opt$mutual_info)
+    sink(opt$HCPC_mutual_info)
     res <- external_validation(
        true_labels = as.numeric(contrasting_factor$factor),
        clusters = as.numeric(res.hcpc$data.clust$clust),
@@ -448,6 +454,7 @@
     legend.col(col = rev(brewer.pal(n = 11, name = "RdYlGn")), lev = cut(contrasting_factor$factor, 11, label = FALSE))
   }
 }
+
 ## Clusters to which individual observations belong # used ?
 # Clust <- data.frame(Cluster = res.hcpc$data.clust[, (nrow(data) + 1)],
 #                     Observation = rownames(res.hcpc$data.clust))
@@ -484,6 +491,31 @@
  
  }
 
+# Description of cluster by most contributing variables / gene expressions
+
+# first transform list of vectors in a list of dataframes
+extract_description <- lapply(res.hcpc$desc.var$quanti, as.data.frame)
+# second, transfer rownames (genes) to column in the dataframe, before rbinding
+extract_description_w_genes <- Map(cbind,
+                                   extract_description,
+                                   genes= lapply(extract_description, rownames)
+                                   )
+# Then use data.table to collapse all generated dataframe, with the cluster id in first column
+# using the {data.table} rbindlist function
+cluster_description <- rbindlist(extract_description_w_genes, idcol = "cluster_id")
+cluster_description = cluster_description[ ,c(8, 1, 2, 3,4,5,6,7)] # reorganize columns
+
+
+# Finally, output cluster description data frame
+write.table(
+    cluster_description,
+    file = opt$HCPC_cluster_description,
+    sep = "\t",
+    quote = F,
+    col.names = T,
+    row.names = F
+    )
+
 }
 
 ## Return coordinates file to user
@@ -509,15 +541,4 @@
     col.names = T,
     row.names = F
     )
-}  
-
-
-
-
-
-
-
-
-
-
-
+}
diff -r 8e17c31c536a -r 569334568afa high_dim_visu.xml
--- a/high_dim_visu.xml	Thu Jul 11 12:31:28 2019 -0400
+++ b/high_dim_visu.xml	Mon Sep 02 04:39:20 2019 -0400
@@ -1,4 +1,4 @@
-<tool id="high_dimensions_visualisation" name="Generate PCA, tSNE and HCPC" version="0.9.4">
+<tool id="high_dimensions_visualisation" name="Generate PCA, tSNE and HCPC" version="0.9.5">
     <description>from highly dimensional expression data</description>
     <requirements>
         <requirement type="package" version="1.6.2=r35h6115d3f_0">r-optparse</requirement>
@@ -7,6 +7,7 @@
         <requirement type="package" version="0.15=r351he1b5a44_0">r-rtsne</requirement>
         <requirement type="package" version="0.4.7=r351h6115d3f_0">r-ggfortify</requirement>
         <requirement type="package" version="1.1.9=r351h0357c0b_0">r-clusterr</requirement>
+        <!--<requirement type="package" version="1.11.6=r351hc070d10_0">r-data.table</requirement>-->
     </requirements>
     <stdio>
         <exit_code range="1:" level="fatal" description="Tool exception" />
@@ -53,6 +54,7 @@
                 --HCPC_max '$visualisation.HCPC_max'
                 --HCPC_clusterCA '$visualisation.HCPC_clusterCA'
                 --HCPC_kk '$visualisation.HCPC_kk'
+                --HCPC_cluster_description '$HCPC_cluster_description'
                 #if $visualisation.res_clustering == "yes":
                     --HCPC_clust '$HCPC_clust'
                 #end if 
@@ -65,7 +67,7 @@
             #end if
             
             #if $visualisation.visu_choice == "HCPC" and $factor_condition.factor_choice == "Yes":
-                --mutual_info '$mutual_info'
+                --HCPC_mutual_info '$HCPC_mutual_info'
             #end if            
 
             --pdf_out '$pdf_out'
@@ -134,34 +136,43 @@
                 <param name="HCPC_npc" value="5" type="integer" label="Number of principal components to keep"
                        help="The number of dimensions which are kept for HCPC analysis (default=5)" />
                 <param name="HCPC_ncluster" value="-1" type="integer" label="Number of clusters in Hierar. Clustering"
-                       help="nb.clust, the number of clusters to consider in the hierarchical clustering. (default : -1, let HCPC to optimize the number)" />
-				<param name="HCPC_metric"  type="select" label="Dissimilarity metric" help="Metric to be used for calculating dissimilarities between observations, available 'euclidian' or 'manhattan'? " > 
-					<option value="euclidian" selected="true">euclidian</option>
+                       help="nb.clust - an integer. If 0, the tree is cut at the level the user clicks on (not working in Galaxy). If -1, the tree is
+                             automatically cut at the suggested level (see details). If a (positive) integer, the tree is cut with nb.cluters clusters." />
+				<param name="HCPC_metric"  type="select" label="Dissimilarity metric" help="Metric to be used for calculating dissimilarities between observations, can be 'euclidean' or 'manhattan' " > 
+					<option value="euclidean" selected="true">euclidean</option>
 					<option value="manhattan">manhattan</option>
 				</param>
-			    <param name="HCPC_method"  type="select" label="Clustering method" help="Clustering method between 'ward', 'average', 'single', 'complete', 'weighted' " > 
+			    <param name="HCPC_method"  type="select" label="Clustering method" help="character string defining the clustering method.
+			           The four methods implemented are 'average' ([unweighted pair-]group [arithMetic] average method, aka ‘UPGMA’),
+			           'single' (single linkage), 'complete' (complete linkage), and 'ward' (Ward's method).
+			           The default with this Galaxy tool is is 'ward'." > 
 					<option value="ward" selected="true">ward</option>
 					<option value="average">average</option>
 					<option value="single">single</option>
 					<option value="complete">complete</option>
-					<option value="weighted">weighted</option>
 				</param>
-				<param name="HCPC_consol"  type="select" label="k-means consolidation" help="If TRUE, a k-means consolidation is performed" > 
+				<param name="HCPC_consol"  type="select" label="k-means consolidation" help="a boolean. If TRUE, a k-means consolidation is performed
+				       (consolidation cannot be performed if kk is used and equals a number)." > 
 					<option value="TRUE" selected="true">Yes</option>
 					<option value="FALSE">False</option>
 				</param>
 				<param name="HCPC_itermax" value="10" type="integer" label="Maximum number of iterations for consolidation"
-                       help=" (default=10)" />
+                       help="An integer. The maximum number of iterations for the consolidation. (default=10)" />
                 <param name="HCPC_min" value="3" type="integer" label="min number of clusters"
-                       help=" The least possible number of clusters suggested (default=3)" />
+                       help="an integer. The least possible number of clusters suggested. (default=3)" />
                 <param name="HCPC_max" value="-1" type="text" label="max number of clusters"
-                       help=" The higher possible number of clusters suggested, by default the minimum between 10 and the number of individuals divided by 2. (default=-1)" />
-				<param name="HCPC_clusterCA"  type="select" label="clusterCA, Clustering against rows or columns" help="default(rows)" > 
+                       help="The higher possible number of clusters suggested, by default the minimum between 10 and the number of individuals divided by 2. (default=-1)" />
+				<param name="HCPC_clusterCA"  type="select" label="cluster.CA, Clustering against rows or columns"
+				       help="A string equals to 'rows' or 'columns' for the clustering of Correspondence Analysis results.default(rows)"> 
 					<option value="rows" selected="true">Rows</option>
 					<option value="cols">Columns</option>
 				</param>
-				 <param name="HCPC_kk" value="-1" type="text" label="kk, Number of clusters used in a Kmeans preprocessing "
-                       help="No k-means consolidation is done if a kk value is provided (default=-1)" />
+				 <param name="HCPC_kk" value="Inf" type="text" label="kk, Number of clusters used in a Kmeans preprocessing "
+                       help="An integer corresponding to the number of clusters used in a Kmeans preprocessing before the
+                             hierarchical clustering; the top of the hierarchical tree is then constructed from this partition.
+                             This is very useful if the number of individuals is high. Note that consolidation cannot be performed
+                             if kk is different from Inf and some graphics are not drawn. Inf is used by default and no preprocessing
+                             is done, all the graphical outputs are then given." />
                 <param label="Return HCPC clustering table" name="res_clustering" type="select">
                     <option value="no" selected="True">No</option>
                     <option value="yes">Yes</option>
@@ -184,14 +195,18 @@
         <data name="table_coordinates" format="tabular" label="Scatter plot coordinates from ${visualisation.visu_choice} of ${on_string}" >
             <filter>coord == 'yes'</filter>
         </data>
-        <data name="mutual_info" format="txt" label="External validation of clustering from ${visualisation.visu_choice} of ${on_string}" >
+        <data name="HCPC_mutual_info" format="txt" label="External validation of clustering from ${visualisation.visu_choice} of ${on_string}" >
             <filter>visualisation['visu_choice'] == 'HCPC' and factor_condition['factor_choice'] == 'Yes'</filter>
         </data>
         <data name="HCPC_clust" format="tabular" label="Clustering table from ${visualisation.visu_choice} of ${on_string}" >
             <filter>visualisation['visu_choice'] == 'HCPC' and visualisation['res_clustering'] == 'yes'</filter>
         </data>
+        <data name="HCPC_cluster_description" format="tabular" label="Cluster information from ${visualisation.visu_choice}" >
+            <filter>visualisation['visu_choice'] == 'HCPC' </filter>
+        </data>
     </outputs>
     <tests>
+        <!-- test first (for developpers) -->
         <!-- test PCA -->
         <test>
             <param name="input" value="cpm_input.tsv" ftype="txt"/>
@@ -271,6 +286,7 @@
             <param name="HCPC_npc" value="5"/>
             <param name="HCPC_ncluster" value="-1"/>
             <output name="pdf_out" file="hcpc.labels.pdf" compare="sim_size" ftype="pdf"/>
+            <output name="HCPC_cluster_description" file="hcpc.cluster_description.1.tab" ftype="tabular"/>
         </test>
         <!-- test factor contrasting on HCPC -->
         <test>
@@ -283,8 +299,9 @@
             <param name="factor_choice" value="Yes" />
             <param name="factor" value="factor.tsv" ftype="txt"/>
             <output name="pdf_out" file="hcpc.nolabels.factor.pdf" compare="sim_size" ftype="pdf"/>
-            <output name="mutual_info" file="hcpc.factor.extval.txt" ftype="txt"/>
+            <output name="HCPC_mutual_info" file="hcpc.factor.extval.txt" ftype="txt"/>
             <output name="HCPC_clust" file="hcpc.clusters.tab" ftype="tabular"/>
+            <output name="HCPC_cluster_description" file="hcpc.cluster_description.1.tab" ftype="tabular"/>
         </test>
         <test>
             <param name="input" value="cpm_input.tsv" ftype="txt"/>
@@ -293,6 +310,7 @@
             <param name="HCPC_ncluster" value="-1"/>
             <param name="visu_choice" value="HCPC" />
             <output name="pdf_out" file="hcpc.nolabels.pdf" compare="sim_size" ftype="pdf"/>
+            <output name="HCPC_cluster_description" file="hcpc.cluster_description.1.tab" ftype="tabular"/>
         </test>
         <test>
             <param name="input" value="cpm_input.tsv" ftype="txt"/>
@@ -304,6 +322,7 @@
             <param name="HCPC_npc" value="4" />
             <output name="pdf_out" file="hcpc-2.labels.pdf" ftype="pdf"/>
             <output name="table_coordinates" file="hcpc-2.coord.tab" ftype="tabular"/>
+            <output name="HCPC_cluster_description" file="hcpc.cluster_description.4.tab" ftype="tabular"/>
         </test>
         <test>
             <param name="input" value="cpm_input.tsv" ftype="txt"/>
@@ -311,11 +330,12 @@
             <param name="visu_choice" value="HCPC" />
             <param name="coord" value="yes" />
             <param name="HCPC_method" value="single"/>
-            <param name="HCPC_metric" value="euclidian"/>
+            <param name="HCPC_metric" value="euclidean"/>
             <param name="HCPC_npc" value="4" />
             <param name="HCPC_clusterCA" value="cols" />
             <output name="pdf_out" file="hcpc-3.labels.pdf" compare="sim_size" ftype="pdf"/>
             <output name="table_coordinates" file="hcpc-3.coord.tab" ftype="tabular"/>
+            <output name="HCPC_cluster_description" file="hcpc.cluster_description.5.tab" ftype="tabular"/>
         </test>
         <!-- test t-SNE -->
         <test>
diff -r 8e17c31c536a -r 569334568afa test-data/hcpc.cluster_description.1.tab
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/hcpc.cluster_description.1.tab	Mon Sep 02 04:39:20 2019 -0400
@@ -0,0 +1,1180 @@
+genes	cluster_id	v.test	Mean in category	Overall mean	sd in category	Overall sd	p.value
+TUSC3	1	11.8890897711964	2.02149769035256	0.820349274023337	3.81496317321131	2.61166315266037	1.34868362907211e-32
+USMG5	1	8.61018275981449	5.36922025791415	4.36307228245837	3.30870030072204	3.02077642160404	7.29441907532539e-18
+TM4SF1	1	6.8501233340706	2.60299136171499	1.64679530949995	4.48210676849274	3.60842472917828	7.37863458923549e-12
+WASF3	1	3.81082062029984	2.72810637690025	2.23304493116436	3.8140236890506	3.35822425701289	0.000138506246351441
+RPS29	1	3.69248178150784	4.44076026507806	4.10483867741957	2.71626848553352	2.35173643708298	0.000222076254209972
+ATP6V0C	1	2.85728617185022	4.1147659118381	3.86757641424506	2.68387039140677	2.23637881955919	0.00427280416431219
+RPS6	1	2.28645686432482	8.05369460415472	7.77324497980439	3.51400575835216	3.1707422903076	0.0222275449023515
+ADD3	1	-2.03898945313383	2.67200952180054	2.97075160954821	3.99658342916655	3.78748156266524	0.04145108017794
+ZNF620	1	-2.09339320365175	0.269607305499926	0.403867056232137	1.45402896093331	1.65792210375095	0.0363140686205794
+AGMO	1	-2.16542265853872	0.550187878554447	0.736036212379138	2.0807096254801	2.21863106726791	0.030355332385656
+ZNF815	1	-2.33839574702057	0.133962973147947	0.246326932456439	1.01648773391031	1.24216164846543	0.0193667281609244
+SNORD116-26	1	-2.40369126298929	0.326022774081065	0.462953397156306	1.3861980093835	1.4726210173554	0.0162304741865377
+ELP4	1	-2.40849812960999	0.974148047514188	1.23114458089402	2.6360911416134	2.75835428689567	0.0160183083673185
+APBB2	1	-2.41667816437009	1.24105212802172	1.52250967335125	2.87073537301846	3.01067012234566	0.0156628589394647
+RYK	1	-2.47171547161999	0.824118979184263	1.06171807888193	2.36953231938935	2.48493715467498	0.0134466490391557
+PRADC1	1	-2.48046576244539	1.14207696618551	1.42011297473606	2.86710513825962	2.89758979425945	0.0131210864071634
+ABHD10	1	-2.5790613250417	0.75353092955207	1.00257720348008	2.32308715173801	2.49624653224482	0.00990691975234645
+TTC14	1	-2.58582678155596	1.39510160792198	1.71612883234859	3.17313325553508	3.20930896865728	0.00971457375210226
+MTBP	1	-2.60912344768115	0.385579544987324	0.579164139504745	1.73636076126248	1.9179852388187	0.00907744888585606
+MYH10	1	-2.61011059239789	1.75799766282434	2.10139225838514	3.41282879858192	3.40097658353322	0.00905129559470747
+C15orf40	1	-2.62147658919973	1.01437618484177	1.28799010778606	2.68426853335147	2.69812026727689	0.00875497751214468
+CMTM6	1	-2.63702536521193	2.26464501565307	2.64201520918745	3.88129677814107	3.69932410486321	0.00836365773852664
+MBTPS2	1	-2.64835122516919	0.874222046215456	1.14554924298665	2.56566099582828	2.64841989757772	0.00808854422244584
+CHEK1	1	-2.7265321223624	0.828111216691287	1.09603981908161	2.40734450237589	2.54025640477418	0.00640037224572248
+ATP1A3	1	-2.73870881202368	0.162426144112341	0.289113068628839	0.90568885226386	1.19579030792616	0.00616809771090977
+CDYL	1	-2.74950588213968	0.948755812856688	1.21874162823553	2.48898715444354	2.53837270703711	0.00596851916139442
+C11orf95	1	-2.75271584151799	0.201272678652178	0.36670211607124	1.26561795452585	1.55353308134087	0.00591031717167873
+LRRC37B	1	-2.75645408913395	0.430147445567389	0.639731413421163	1.78964084524244	1.96551512360064	0.00584318149839236
+ARID3B	1	-2.77139122842724	0.13567672674334	0.281948740024639	1.03648156492496	1.36437105082851	0.00558173175028376
+STX2	1	-2.83088173246747	1.11241017928898	1.41308526331391	2.70073561840279	2.74564769283462	0.00464198818823589
+CCDC163P	1	-2.8340985159593	0.307788589687561	0.509243236341225	1.53259005866322	1.83751732036673	0.00459551624555987
+RPS18	1	-2.902994689542	8.38921855977543	8.64191423816786	2.877729925673	2.25019765786645	0.00369612904490891
+MASP2	1	-2.92108579293095	0.257935169716606	0.412019090856802	1.16071727032867	1.36358465227773	0.00348813758190286
+SPG11	1	-2.96757376764542	1.6731212828341	2.04238640526762	3.25437143467824	3.21666520682275	0.00300160246901385
+KCNC4	1	-3.12046634557205	0.0410437009288487	0.164064559520356	0.563838938809914	1.01912708938708	0.00180564929402491
+TEAD2	1	-3.15247223053577	0.251912984600313	0.423615860647351	1.19333271678008	1.40797646387669	0.00161894219494459
+LRFN1	1	-3.16466646135369	0.061336699400226	0.191118271995341	0.575880501223955	1.06011793720616	0.00155260821115874
+MMS22L	1	-3.1907511006789	0.675406871624816	0.997601457649576	2.33080276617111	2.6103239362368	0.00141903471070453
+SGK223	1	-3.21261995996212	0.240701420408819	0.437179495534188	1.28082809780442	1.58097075534843	0.0013153020715321
+ZNF772	1	-3.22123341193102	0.240495802575651	0.434955270683052	1.2294001721805	1.56054391082076	0.00127640148463538
+LPAR6	1	-3.28150750742381	0.317394897252685	0.559767633053026	1.57973867660451	1.90932323604038	0.00103253775760717
+NAIF1	1	-3.30639354249097	0.0968824123044998	0.261360429304809	0.89567213660756	1.2859450536684	0.000945052538018326
+CUEDC1	1	-3.32854787551463	0.355237585896492	0.588476544530035	1.56183512350189	1.81140424349499	0.00087299999045148
+RSAD2	1	-3.33508689568094	0.16951518774909	0.3868337017252	1.10713362224153	1.68445210809055	0.000852727481904465
+IK	1	-3.39417275771268	3.32119209471634	3.83728051825396	4.12347086858661	3.9306037944107	0.000688362535711771
+SMAD5	1	-3.42697016284732	2.4959205748787	2.93258924523917	3.51671407644777	3.29390299818345	0.000610356131126268
+RCHY1	1	-3.43083102601818	1.01695286786146	1.41771757685026	2.83655342318108	3.01966828068613	0.000601735297897463
+LRRCC1	1	-3.549390342322	1.38126744542132	1.81632641109665	3.10638419391875	3.16857108526568	0.000386124247039099
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+NR2C2	3	2.38562109453754	1.51184956984908	1.15444994122998	2.4892362738085	2.54688849405328	0.0170503080032895
+CNTNAP1	3	2.37819683198808	1.28690971618738	0.972825791556814	2.30939870708895	2.24520093092361	0.0173975364339062
+PER1	3	2.34477399114092	3.12104656444108	2.66113998977203	2.93185803988654	3.33446321583541	0.0190386163231545
+ZNF815	3	2.29743937061733	0.414193756810119	0.246326932456439	1.46176746288646	1.24216164846543	0.0215937180056699
+ABHD10	3	2.24533311965586	1.3322711370725	1.00257720348008	2.56434812404649	2.49624653224482	0.0247467553845599
+C17orf80	3	2.2163795970127	1.20710579778302	0.890921154292548	2.59799496245609	2.42523557698211	0.0266655158231351
+TRIM2	3	2.17484097110458	2.31882264875011	1.91471051768566	2.96834324870494	3.15886948600908	0.0296420356384355
+ABHD14A	3	2.16757904470942	1.82286676157307	1.45010520618288	2.91186926749266	2.92356983533123	0.0301907295651873
+SNORD116-26	3	2.16181060992185	0.650216121617399	0.462953397156306	1.44461640746217	1.4726210173554	0.0306327773405748
+KCNC4	3	2.14343973949296	0.292558403981425	0.164064559520356	1.35142690215557	1.01912708938708	0.0320778049876396
+HRASLS	3	2.10768077799917	0.931853774366771	0.672637228800667	2.23547120645236	2.09081296655755	0.0350586110828418
+ATP9A	3	2.0338138604152	2.15605197279304	1.78370411170285	2.95820104057958	3.11239681035548	0.041970366521337
+NAB1	3	2.02671137429921	1.43403970481113	1.12708657781216	2.66855824747581	2.57476417637419	0.0426919385611801
+PROX1	3	1.99444661432834	0.854090843476411	0.627549643425384	2.1473310415848	1.93099914571308	0.0461032686442205
+CCDC163P	3	1.99023702369186	0.724362321144492	0.509243236341225	1.99708110508895	1.83751732036673	0.0465648316478792
+HTT	3	1.97251474332772	2.02575312872827	1.66910845650959	2.94451447212473	3.0737800216287	0.0485508749431717
+APBB2	3	1.9698610893451	1.87136187924366	1.52250967335125	2.91641413464314	3.01067012234566	0.0488542929526014
+ZCCHC10	3	1.96146943257803	1.76888948573471	1.45564531061548	2.54082931423614	2.71493077358942	0.0498242873934793
+RUFY3	3	-1.96556424613337	2.91599964696109	3.33656991956503	3.0368084988776	3.63754713141573	0.049348967556493
+DAAM2	3	-2.08383214167104	0.525977748461017	0.824225925551688	1.84000134978044	2.43316951363754	0.0371754385745041
+STOX2	3	-2.41400357335001	0.30173023636278	0.575761068032365	1.32073203594924	1.92982896728664	0.0157783076180194
+ATCAY	3	-3.05261662545276	0.265572228014968	0.65850184432408	1.40689219170703	2.18826442404855	0.00226855558993392
+LOC375010	3	-3.56957664125158	0.105820150672655	0.401806902977271	0.670055528133466	1.40965508832916	0.000357558601448744
+BCAN	3	-4.24738714298154	5.51650656602858	6.77485459849344	4.85131015504388	5.03658568935348	2.16278049005184e-05
+TUSC3	3	-5.12874214201938	0.0324499543953149	0.820349274023337	0.486749315929723	2.61166315266037	2.91684545621196e-07
+TM4SF1	3	-5.13006974665495	0.557906287691052	1.64679530949995	2.04251649806878	3.60842472917828	2.89634843069756e-07
diff -r 8e17c31c536a -r 569334568afa test-data/hcpc.cluster_description.4.tab
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/hcpc.cluster_description.4.tab	Mon Sep 02 04:39:20 2019 -0400
@@ -0,0 +1,1231 @@
+genes	cluster_id	v.test	Mean in category	Overall mean	sd in category	Overall sd	p.value
+TUSC3	1	9.64226245491482	1.58846421413198	0.820349274023337	3.47195156241725	2.61166315266037	5.30066060421869e-22
+USMG5	1	5.75087525581821	4.89295851056519	4.36307228245837	3.37773714868832	3.02077642160404	8.87826071601112e-09
+TM4SF1	1	4.30513402655702	2.12063826557369	1.64679530949995	4.15092195695276	3.60842472917828	1.66884668352345e-05
+WASF3	1	2.3686373498309	2.47567150728554	2.23304493116436	3.69290575886789	3.35822425701289	0.0178537498791563
+RPS6	1	-2.02142946490481	7.57774368453375	7.77324497980439	3.69929873265015	3.1707422903076	0.0432353271268453
+STOX2	1	-2.03230776521167	0.456131537141282	0.575761068032365	1.83974078909003	1.92982896728664	0.0421225088463805
+ZNF815	1	-2.05822775838923	0.168343625205738	0.246326932456439	1.13094339680922	1.24216164846543	0.0395682751672086
+HRASLS	1	-2.18810433400509	0.533092539417367	0.672637228800667	1.97970470343026	2.09081296655755	0.028662003293977
+RGS7	1	-2.19551232796286	0.424265280907165	0.556758256852023	1.84269641043328	1.97845817099046	0.0281268675582295
+SLC46A3	1	-2.19932643401432	0.144982391527422	0.231122889495804	1.00665735588557	1.28406669500027	0.0278547194069885
+DNAJC17	1	-2.2153408664982	0.815241917974638	0.978307347644039	2.44709487688109	2.41318844957258	0.0267366768381965
+SNORD116-26	1	-2.21953922153784	0.363255976963148	0.462953397156306	1.4602107605625	1.4726210173554	0.0264500619619391
+TRAF4	1	-2.23773936356703	1.69986945892419	1.89578850077877	2.99570575438043	2.87036446279182	0.0252380566805772
+MMS22L	1	-2.32530639430104	0.812459567234433	0.997601457649576	2.51271571130503	2.6103239362368	0.020055582629047
+C5orf27	1	-2.37942814531418	0.104218712338521	0.18554210390183	0.953354062599462	1.1205023866099	0.0173395232010564
+ZCCHC10	1	-2.40556425925154	1.25643774649768	1.45564531061548	2.73941541051855	2.71493077358942	0.0161475118508051
+TTC14	1	-2.48944983976246	1.47243473389029	1.71612883234859	3.20125431782565	3.20930896865728	0.0127940970848194
+CHEK1	1	-2.53589088145139	0.899550829542027	1.09603981908161	2.48119916324396	2.54025640477418	0.0112161677129475
+RPAP3	1	-2.59774718945401	1.52814380345402	1.76725140318432	3.05468847817467	3.01763281678623	0.00938375529133339
+WWC2	1	-2.59959178971297	0.434865234502408	0.595926378611705	1.87327021566575	2.03121325052878	0.00933347134960858
+DAAM2	1	-2.60045996272108	0.631228000366455	0.824225925551688	2.22216377988788	2.43316951363754	0.00930988819751711
+C11orf95	1	-2.64983816898038	0.241136723338671	0.36670211607124	1.33994462312251	1.55353308134087	0.00805303345340468
+KCNC4	1	-2.69074382136831	0.0804213287073027	0.164064559520356	0.717534516880271	1.01912708938708	0.00712929172422702
+CCDC163P	1	-2.72203965827676	0.356677857467215	0.509243236341225	1.65444314216044	1.83751732036673	0.00648803559183824
+TEAD2	1	-2.72205213103367	0.306713862196619	0.423615860647351	1.29194034433089	1.40797646387669	0.00648779071783175
+APBB2	1	-2.73295325990364	1.27153755341687	1.52250967335125	2.91866490815852	3.01067012234566	0.00627692391190147
+SPG11	1	-2.73871751141408	1.77367679292943	2.04238640526762	3.2337267763403	3.21666520682275	0.00616793451653255
+STX2	1	-2.76679359551292	1.18137158364863	1.41308526331391	2.70980195371616	2.74564769283462	0.00566105846815189
+AGMO	1	-2.8623935940156	0.542329556532382	0.736036212379138	2.04397579179877	2.21863106726791	0.00420454412911027
+SGK223	1	-2.8823814334399	0.298182507246432	0.437179495534188	1.3843946429886	1.58097075534843	0.00394681641324358
+ARID3B	1	-2.92176200377281	0.160356058802522	0.281948740024639	1.09436788539651	1.36437105082851	0.00348057392403883
+ZNF772	1	-2.93236680343932	0.295374886319228	0.434955270683052	1.34358301617205	1.56054391082076	0.00336389183213697
+MASP2	1	-2.94866632231244	0.289377482828885	0.412019090856802	1.26262842273047	1.36358465227773	0.00319148356121039
+TP53INP1	1	-2.96463514605474	0.617153570233708	0.800315053536902	1.90121590851185	2.0255025620396	0.00303042102637058
+ELP4	1	-2.98792551027535	0.979753471111881	1.23114458089402	2.62672279402127	2.75835428689567	0.00280878002742779
+RSAD2	1	-2.99013684834085	0.233202355959127	0.3868337017252	1.26614635025896	1.68445210809055	0.00278852486614307
+RYK	1	-3.01631090390108	0.833094185729773	1.06171807888193	2.37849760283947	2.48493715467498	0.00255870756057118
+ATP2B2	1	-3.13437297595946	0.238991178797506	0.384528572053305	1.25759861754222	1.52227745503338	0.00172221799339941
+LRIG3	1	-3.14882676607082	0.222452140588039	0.372582215414645	1.29333402861645	1.5631074409039	0.00163927339228592
+ZNF544	1	-3.2287359504238	0.740895453853218	0.978607334849696	2.24714497142373	2.41372760330092	0.00124338640863497
+EPN2	1	-3.27035073735749	2.43496995921139	2.77254780994505	3.43249673873756	3.38414925862716	0.00107414212241518
+RPS18	1	-3.29801495906207	8.41555230633911	8.64191423816786	2.77581386163632	2.25019765786645	0.000973709468012838
+ATP1A3	1	-3.31917253220042	0.168049085352608	0.289113068628839	0.910317048993741	1.19579030792616	0.000902846281812626
+MTBP	1	-3.32091804819734	0.384881712077264	0.579164139504745	1.73823679369761	1.9179852388187	0.000897218783204695
+LRRC37B	1	-3.33396404174905	0.439852305045517	0.639731413421163	1.77859456953113	1.96551512360064	0.000856177253431898
+SPIN4	1	-3.38034695391791	0.0770852458179392	0.17477396032571	0.688876241457225	0.947442832475607	0.0007239438052784
+BOLA3-AS1	1	-3.48769696661068	0.358627443870704	0.564432464698574	1.6771241420016	1.93458189842836	0.000487199921846061
+LOC286467	1	-3.48833290906418	0.248612536583686	0.4233647053482	1.3532477887989	1.64238340042071	0.000486042502518013
+TDRD7	1	-3.49416324141906	0.206945242651803	0.375367845357064	1.25937748124315	1.58025466698857	0.000475550144139792
+C15orf40	1	-3.50112347972175	0.999853237648716	1.28799010778606	2.65403708979844	2.69812026727689	0.000463301126082049
+BOD1L	1	-3.50545233479716	1.80736208026619	2.14709712010777	3.20083203683018	3.17735816748594	0.000455832114008195
+MYH10	1	-3.50547415439114	1.73774483617152	2.10139225838514	3.35772869710029	3.40097658353322	0.000455794752685397
+ATG16L2	1	-3.51587396115506	0.381030768232195	0.591808182204551	1.73229535089736	1.96544398879298	0.000438309007004495
+LRFN1	1	-3.52945579010502	0.0769903180802121	0.191118271995341	0.651984331854209	1.06011793720616	0.000416415272602038
+SDCCAG8	1	-3.55332620439281	2.87835636278365	3.28401104577321	3.89859240604234	3.7427542581373	0.000380392453076528
+MLLT10	1	-3.56342936288234	0.806516370913779	1.08106729382237	2.41422823003888	2.52594942903587	0.00036604122675754
+CDYL	1	-3.57289678495735	0.942107369917387	1.21874162823553	2.43331753929673	2.53837270703711	0.000353053945301451
+ABHD10	1	-3.57584324260533	0.730309549816878	1.00257720348008	2.27389911487868	2.49624653224482	0.000349100800794316
+INVS	1	-3.60350820948268	0.439248986504451	0.667892942896287	1.79258283285398	2.0801952887827	0.000313950826568254
+FMR1	1	-3.65474283132078	0.820721367034913	1.09504869907744	2.31389724348614	2.46083307155157	0.000257439899011093
+SGSM2	1	-3.69067681734685	0.884625704330811	1.18857342546738	2.42746609437599	2.69999383525672	0.000223658155567998
+MBTPS2	1	-3.71185426966082	0.845696613674801	1.14554924298665	2.48916312229151	2.64841989757772	0.000205746440809326
+RFX7	1	-3.79665122902927	1.1026256911837	1.42719072352901	2.68186028732554	2.80266327540895	0.000146663904970361
+DLG2	1	-3.84073756217631	0.466468398166941	0.713632633124568	1.79378253074763	2.10979808068387	0.000122665198986215
+LINGO1	1	-3.8774775220061	0.133417491802602	0.2897099718993	1.00456058670107	1.32147420968444	0.000105545075411079
+CACNA1D	1	-3.89911839896936	0.279917435239515	0.487079449811966	1.43041716242407	1.74186142144313	9.65435605734855e-05
+CUEDC1	1	-3.9085838552307	0.372520722531684	0.588476544530035	1.60159330520339	1.81140424349499	9.28387235753677e-05
+STK38L	1	-3.92316668252425	1.20456142138519	1.54916496873415	2.72872927441598	2.87973736405291	8.73926440543552e-05
+RBFA	1	-3.98886984678286	0.705175689390408	1.0004027114715	2.22656624603345	2.42647676927307	6.63888328140774e-05
+EYA3	1	-4.02628672557331	1.02228203407901	1.35977296568482	2.63252554026369	2.74806693326301	5.66645872458669e-05
+MDGA1	1	-4.03733062225179	0.175367606293413	0.359470309447907	1.15148033476185	1.49498125507126	5.40628515442421e-05
+RCHY1	1	-4.04575020564079	1.04507849243921	1.41771757685026	2.84031827244055	3.01966828068613	5.21558252633022e-05
+BAZ2B	1	-4.05963372451464	2.98291334849903	3.46955435390984	4.03767296928145	3.92999272916627	4.91497535068964e-05
+COX19	1	-4.0633099489556	1.04717151858784	1.38364780467688	2.49630817015669	2.71484105443514	4.83817168601867e-05
+ZBTB41	1	-4.06369752769733	0.695019285031676	0.983769839671932	2.16285458169071	2.32954631975061	4.83014102657277e-05
+NAIF1	1	-4.08075153853225	0.101296797209109	0.261360429304809	0.883627127525527	1.2859450536684	4.48903204044374e-05
+WASH3P	1	-4.10273774407669	1.24619485973781	1.48088514896608	2.02178119281593	1.87538855462554	4.08289961043602e-05
+F8	1	-4.14037976710701	0.232070091281346	0.45450955360202	1.41132200915057	1.76133334387751	3.46731309366299e-05
+LOC81691	1	-4.1404305739176	0.252208304212505	0.469882025608552	1.31677524993704	1.72357582133597	3.46654517252852e-05
+MED6	1	-4.14508607027482	1.0658212996354	1.43500408825595	2.75183996487767	2.91996597540948	3.39686094618632e-05
+ARX	1	-4.2112248604317	0.172380466442802	0.353019433607072	1.06616104582163	1.40628358633916	2.53989770336622e-05
+VPS8	1	-4.30924803407746	0.92980234009054	1.29336467133036	2.55746611102045	2.76596885243398	1.63810569720317e-05
+HTT	1	-4.31311331096887	1.26472465237608	1.66910845650959	2.94717251561679	3.0737800216287	1.60971564002092e-05
+CKB	1	-4.33003249462383	6.35883899919244	6.93357071400818	4.72252883225593	4.35154927181016	1.49087340487905e-05
+IFIH1	1	-4.33169655070477	0.292467887824633	0.544017857768751	1.51011099113929	1.90386496621516	1.47964776486873e-05
+PPP1R26	1	-4.36452187411764	0.273588701160343	0.520444320262239	1.37095266238021	1.85428395662307	1.27401101575091e-05
+TREX1	1	-4.39087953186675	1.35608825325699	1.7919003470775	3.17645761352935	3.25400078707718	1.12893077632194e-05
+CRTC2	1	-4.40643801408414	0.69615013354609	0.993426452446323	2.05658398496028	2.21178316035361	1.05084361665088e-05
+KCNN2	1	-4.40883712591948	0.275483378426534	0.517939163757791	1.40184983886512	1.8029280441539	1.03927145151164e-05
+PAK6	1	-4.46519481563852	0.113064692936538	0.303535832268129	0.906705012569382	1.39848774699096	7.99959270860575e-06
+TAF6L	1	-4.46945643823333	0.745144189884435	1.08448977411488	2.21493415968043	2.48918623858825	7.84186275749523e-06
+SLC31A1	1	-4.49838590948353	0.754148688872327	1.11859900663016	2.35662680308576	2.65614341754297	6.8471324814658e-06
+SAMD9	1	-4.50982880063011	0.344330549855162	0.617176799570363	1.54846708209069	1.98348002333372	6.48799632860953e-06
+GPD1	1	-4.51268972085927	0.0323599198404997	0.197812246309903	0.415264708869093	1.20200784560883	6.40106320946512e-06
+ZNF600	1	-4.53077720694437	0.159581396496353	0.368118728296182	1.03798322322785	1.50897138186057	5.87670878918232e-06
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+ASPH	2	4.54878308551269	4.64383681432478	3.21715306636289	3.99436121476934	3.75538065046214	5.39570242886147e-06
+IPO13	2	4.54580972771503	3.03633303738867	1.810818439012	3.89703506879431	3.22796422573348	5.472445724932e-06
+GTF3C1	2	4.52737863740943	3.24449716383996	2.04165163818533	3.68895653282222	3.18115270774038	5.97198782460916e-06
+DENND5A	2	4.52242537551095	5.96163439870209	4.4529342666832	3.39509264579754	3.99441327808131	6.11350433037917e-06
+QDPR	2	4.49290537225992	3.93825500830328	2.53311053778265	4.09140847899178	3.74468408229745	7.02580087064189e-06
+ZNF324	2	4.4905158429427	1.59686186173268	0.747820027234708	3.03247841583969	2.2638848559232	7.1050889730171e-06
+ZNF853	2	4.48852515089822	1.75490860602837	0.879601135637988	3.12014017380404	2.33495464795379	7.17179581735982e-06
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+PER1	2	4.46776164932704	3.90535217144616	2.66113998977203	3.40647711432784	3.33446321583541	7.90423038036116e-06
+DTX3L	2	4.45110308249807	2.17121861892601	1.23739161329133	3.22420379554836	2.51200358450226	8.54303181982533e-06
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+NBPF14	2	4.16008474082023	2.77621174490136	1.91995739606063	2.70680466523195	2.46446179891936	3.18129537071364e-05
+VAMP5	2	4.12888140737803	3.32811138004567	2.21171903827709	3.68532582899992	3.23747122748596	3.64532351980296e-05
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+ZDHHC15	2	3.90437927106119	2.0214144966255	1.17214074434731	3.08107787492276	2.60445693822036	9.44675352714406e-05
+IFIT3	2	3.8894346498115	1.95321829501923	1.059998363872	3.63946921885743	2.7497512242036	0.000100478020349575
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+CDYL	3	2.50249516945402	1.47795271986729	1.21874162823553	2.56239201715852	2.53837270703711	0.0123321308378778
+EFR3A	3	2.47216346274349	1.0669586681966	0.83931863074403	2.34992290575641	2.2565581070256	0.0134298093298929
+ZFP3	3	2.41383548211053	0.842991526226978	0.639565939142642	2.27386732027471	2.06525160076458	0.015785588207518
+RCHY1	3	2.39128030002106	1.712373154738	1.41771757685026	3.02887011370944	3.01966828068613	0.0167897291940208
+PAK6	3	2.36383597341504	0.438432414627862	0.303535832268129	1.64088173795079	1.39848774699096	0.0180868185196747
+APBB2	3	2.35987721960412	1.81242923831731	1.52250967335125	3.02144809984009	3.01067012234566	0.0182809844115157
+UBC	3	2.34953471247668	10.1034988631167	9.89779819432538	1.41372673849151	2.14550185456567	0.0187968913496349
+ZNF324	3	2.34281463237149	0.964249900830991	0.747820027234708	2.45256350546755	2.2638848559232	0.0191388892782472
+PCYOX1L	3	2.34200587932871	0.561188123933646	0.40259020698957	1.86887423233045	1.659527885003	0.0191804127758552
+TP53BP1	3	2.31181360123722	2.42490160053227	2.1105997390144	3.27100146027699	3.3317253636435	0.0207879575592664
+NEDD4	3	2.20243146349018	0.647440232859171	0.493964387877776	1.8700112541051	1.70770435816441	0.0276348454179129
+HTT	3	2.14195560470757	1.9377716621594	1.66910845650959	2.96094434449207	3.0737800216287	0.0321970546818232
+C5orf27	3	2.118200411599	0.282393252969651	0.18554210390183	1.25257755853282	1.1205023866099	0.0341580983537457
+RBFA	3	2.05671265264104	1.2040481568232	1.0004027114715	2.45903307659515	2.42647676927307	0.0397138743684256
+GGNBP2	3	1.99226102264326	2.83578197712859	2.54163127541327	3.52165800734417	3.61825113273262	0.0463424259171628
+WASF3	3	-1.97299383591659	1.96267376988921	2.23304493116436	2.86734538723052	3.35822425701289	0.0484962646269708
+EPHA5	3	-2.03137875072903	0.180627152178204	0.292465160172108	1.04492956698313	1.34919143072828	0.0422165882905018
+DLG2	3	-2.10604642575557	0.532317615239379	0.713632633124568	1.71006015804729	2.10979808068387	0.0352003198101983
+LINGO1	3	-2.67537617220353	0.14544247715541	0.2897099718993	0.904007291097029	1.32147420968444	0.00746454424640138
+TMEM132E	3	-3.3723944903448	0.125363326527411	0.331346363814133	0.844337064388054	1.49681505578475	0.000745176314647712
+METTL21B	3	-3.67072470186015	0.846569823004704	1.27841167654757	2.20047564716678	2.88302211137892	0.00024186373620375
+STOX2	3	-3.72340998587102	0.282547121201268	0.575761068032365	1.27567845268891	1.92982896728664	0.00019654995747466
+TBK1	3	-3.80991414940777	2.16342125308034	2.76772907492921	3.01048034398361	3.88703169824627	0.000139015055760674
+ATP1A3	3	-4.12584583486155	0.0877902653674097	0.289113068628839	0.627132225746354	1.19579030792616	3.69374652831453e-05
+LOC375010	3	-4.48691661902359	0.14370820952613	0.401806902977271	0.835012299240316	1.40965508832916	7.22613381648527e-06
+ATCAY	3	-6.68741828587521	0.0613521258579358	0.65850184432408	0.595008072616697	2.18826442404855	2.27141963717322e-11
+TUSC3	3	-7.69762398316331	0	0.820349274023337	0	2.61166315266037	1.38619567506484e-14
+TM4SF1	3	-8.01222518697363	0.467029676227031	1.64679530949995	1.86648693610858	3.60842472917828	1.12651355511703e-15
diff -r 8e17c31c536a -r 569334568afa test-data/hcpc.cluster_description.5.tab
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/hcpc.cluster_description.5.tab	Mon Sep 02 04:39:20 2019 -0400
@@ -0,0 +1,1178 @@
+genes	cluster_id	v.test	Mean in category	Overall mean	sd in category	Overall sd	p.value
+TUSC3	1	11.9142858023152	2.02648904267441	0.820349274023337	3.81834581414514	2.61166315266037	9.97169617739689e-33
+USMG5	1	8.39755631476141	5.34636759612311	4.36307228245837	3.3204661574193	3.02077642160404	4.55865936650362e-17
+TM4SF1	1	6.88218287090609	2.60941850087972	1.64679530949995	4.48576784413717	3.60842472917828	5.89422778470414e-12
+WASF3	1	3.78804329877795	2.7261473017572	2.23304493116436	3.81852542872013	3.35822425701289	0.00015183839224081
+RPS29	1	3.36197375608184	4.41131394198962	4.10483867741957	2.7351913375762	2.35173643708298	0.000773874782658214
+ATP6V0C	1	2.64343334249021	4.09672975637321	3.86757641424506	2.6906858747661	2.23637881955919	0.00820699234409541
+RPS6	1	1.9777744504986	8.01632550667148	7.77324497980439	3.52255161003573	3.1707422903076	0.0479541570055733
+ZNF620	1	-2.07878964426128	0.270273002550543	0.403867056232137	1.4557611571776	1.65792210375095	0.0376366891379128
+AGMO	1	-2.08191619913202	0.556991790107324	0.736036212379138	2.08453013698814	2.21863106726791	0.0373501248617856
+APBB2	1	-2.1832079037567	1.2677265077872	1.52250967335125	2.90243241589936	3.01067012234566	0.0290205029796916
+ZNF815	1	-2.32678422498413	0.134293745921152	0.246326932456439	1.0177200599424	1.24216164846543	0.0199767524273052
+ELP4	1	-2.38111806585087	0.97655335133521	1.23114458089402	2.63889855168192	2.75835428689567	0.0172601789526045
+MYH10	1	-2.4243312064678	1.7817913130756	2.10139225838514	3.42823925180293	3.40097658353322	0.0153366110315032
+RYK	1	-2.44557782480834	0.826153840861261	1.06171807888193	2.37210154075964	2.48493715467498	0.0144620232821911
+PRADC1	1	-2.4503290948784	1.1448969093119	1.42011297473606	2.87008019864207	2.89758979425945	0.0142725699896127
+TTC14	1	-2.55289299431199	1.39854630325018	1.71612883234859	3.17629001564075	3.20930896865728	0.0106832311962012
+MTBP	1	-2.59102702751887	0.386531593246552	0.579164139504745	1.73839725445096	1.9179852388187	0.00956899759679775
+C15orf40	1	-2.59221270246891	1.01688081739694	1.28799010778606	2.68710653017546	2.69812026727689	0.00953607926535192
+MBTPS2	1	-2.65164566563922	0.873332525126112	1.14554924298665	2.56876399706419	2.64841989757772	0.0080100553304747
+CHEK1	1	-2.70023770041709	0.830155935744846	1.09603981908161	2.40996255548212	2.54025640477418	0.00692899507443975
+ABHD10	1	-2.70765455487023	0.740582089555338	1.00257720348008	2.31127327805414	2.49624653224482	0.00677605118769611
+CDYL	1	-2.7201219581976	0.951098419802013	1.21874162823553	2.49161101345974	2.53837270703711	0.00652578429484909
+ATP1A3	1	-2.72450292032954	0.162827196320026	0.289113068628839	0.906770289877791	1.19579030792616	0.00643983608448314
+LRRC37B	1	-2.73692420699956	0.43120953802558	0.639731413421163	1.79172111506069	1.96551512360064	0.00620165795934135
+ARID3B	1	-2.75943700177248	0.136011731006904	0.281948740024639	1.03773842936566	1.36437105082851	0.00579010497136191
+CCDC163P	1	-2.77485699721825	0.311598838187312	0.509243236341225	1.53501594796301	1.83751732036673	0.00552259851734494
+CMTM6	1	-2.84756325103249	2.23368809110746	2.64201520918745	3.86990366263983	3.69932410486321	0.00440553386539292
+SPG11	1	-2.92842363025605	1.67725244649542	2.04238640526762	3.25732326971356	3.21666520682275	0.00340685514464157
+LPAR6	1	-2.94392475221878	0.341887001952234	0.559767633053026	1.64726553138554	1.90932323604038	0.00324078783413151
+SNORD116-26	1	-2.95415397354776	0.294322720175404	0.462953397156306	1.31602775897663	1.4726210173554	0.0031352753412472
+MASP2	1	-2.96078099220659	0.255523952635908	0.412019090856802	1.16113336439972	1.36358465227773	0.0030686006009995
+CUEDC1	1	-2.96908851478637	0.380002982248077	0.588476544530035	1.63051157922365	1.81140424349499	0.00298684545770977
+C11orf95	1	-3.0534548508746	0.182826360599404	0.36670211607124	1.21144359387023	1.55353308134087	0.00226222760185993
+STX2	1	-3.08199287071715	1.08507389078086	1.41308526331391	2.68035553367091	2.74564769283462	0.00205619762027185
+KCNC4	1	-3.11157328871549	0.041145043400278	0.164064559520356	0.564530914015289	1.01912708938708	0.00186093275136576
+TEAD2	1	-3.13468272154639	0.252534991969697	0.423615860647351	1.19473932294892	1.40797646387669	0.00172040073764027
+LRFN1	1	-3.15456362977436	0.0614881480407204	0.191118271995341	0.576582951119053	1.06011793720616	0.00160738323114292
+MMS22L	1	-3.16779913440029	0.677074542912778	0.997601457649576	2.33343659153863	2.6103239362368	0.00153597603403457
+RPS18	1	-3.179985312323	8.36454503172133	8.64191423816786	2.87412885661753	2.25019765786645	0.00147282517203283
+SGK223	1	-3.19640729289242	0.241295744903655	0.437179495534188	1.28235247741858	1.58097075534843	0.00139150535108692
+ZNF772	1	-3.20488472737201	0.241089619372134	0.434955270683052	1.23085886003934	1.56054391082076	0.00135116581500036
+NAIF1	1	-3.29488978888075	0.0971216281373504	0.261360429304809	0.896764269227696	1.2859450536684	0.000984602872947951
+RSAD2	1	-3.32191364452947	0.169933743768224	0.3868337017252	1.10846752826534	1.68445210809055	0.000894023584316117
+CKB	1	-3.35695718964487	6.36732859596647	6.93357071400818	4.7982078834832	4.35154927181016	0.000788053134785718
+SMAD5	1	-3.37375390023105	2.50182795731945	2.93258924523917	3.51868475485455	3.29390299818345	0.000741506281623818
+GGNBP2	1	-3.46818314496491	2.05520929494939	2.54163127541327	3.57917786699521	3.61825113273262	0.00052399004697452
+F8	1	-3.54289335166126	0.212622793322917	0.45450955360202	1.3990726204623	1.76133334387751	0.00039576271701002
+IK	1	-3.5904574466469	3.29023745595213	3.83728051825396	4.11659893760532	3.9306037944107	0.000330098120893531
+LOC152217	1	-3.61228846614436	2.55988306223326	3.09183367447957	4.03511705529418	3.79906240068932	0.000303506666694008
+FMR1	1	-3.62320697528914	0.749437537146445	1.09504869907744	2.26081326181732	2.46083307155157	0.000290972802456708
+IFIH1	1	-3.63063987712589	0.27608142108593	0.544017857768751	1.49092943329761	1.90386496621516	0.000282719433499816
+TRAPPC9	1	-3.63614985914682	0.427059550698446	0.719748948006064	1.81820966123887	2.07659954710795	0.000276743372905102
+ZBTB44	1	-3.66064286949199	0.712643416604638	1.04281214425939	2.11761352635926	2.3268378145973	0.000251583223009656
+ZNF544	1	-3.66574815184242	0.635631641334592	0.978607334849696	2.02993277871155	2.41372760330092	0.000246616538597091
+LRRCC1	1	-3.67604473303674	1.36482750342376	1.81632641109665	3.09252626212862	3.16857108526568	0.000236878004457196
+ZNF600	1	-3.73051440402666	0.149914990290207	0.368118728296182	1.01757985312516	1.50897138186057	0.000191089217541963
+RCHY1	1	-3.7439125760936	0.979492326625733	1.41771757685026	2.79637218358964	3.01966828068613	0.000181176714838536
+APITD1	1	-3.76213909409643	0.320793922218659	0.578279254861118	1.4337085494996	1.76565230248613	0.000168466307310824
+TP53INP1	1	-3.77157684431489	0.504194727294164	0.800315053536902	1.76941935423853	2.0255025620396	0.000162219184408735
+DNAJC4	1	-3.77255075793888	1.14461070500763	1.56062738391994	2.80802182870615	2.84487500336036	0.000161587080111861
+MDGA1	1	-3.77555770748273	0.140679375825536	0.359470309447907	1.07935996659171	1.49498125507126	0.000159650056906796
+SPIN3	1	-3.78421543887805	0.256666182287134	0.539784681986102	1.41044030472908	1.93010054512115	0.000154194215257884
+RBFA	1	-3.78676994671034	0.644232559867378	1.0004027114715	2.15286980973944	2.42647676927307	0.000152618278814279
+NCK1	1	-3.78922255240468	0.951354527241752	1.371666566707	2.65190722012955	2.86160216099051	0.000151119485260771
+STK38L	1	-3.80271857568204	1.12468272416137	1.54916496873415	2.68479553446412	2.87973736405291	0.0001431169011821
+TREX1	1	-3.81862314546624	1.31024441232393	1.7919003470775	3.14118745218835	3.25400078707718	0.000134198589072642
+INVS	1	-3.82042198020331	0.35983819615892	0.667892942896287	1.63905409861919	2.0801952887827	0.000133223543880927
+MED6	1	-3.83265956272788	1.00120313987606	1.43500408825595	2.69901119117911	2.91996597540948	0.000126765324348903
+SAMD8	1	-3.83463311484214	1.34487630478113	1.79868729105419	2.88984290808818	3.05308380446235	0.00012575185540246
+COX19	1	-3.88367339994558	0.974952573536832	1.38364780467688	2.43462169859112	2.71484105443514	0.000102890093923031
+UTP14A	1	-3.88539097869928	0.440820588349449	0.773570745614314	1.84979249498286	2.20938336775412	0.000102165333339997
+SNRNP25	1	-3.88923166758326	2.52153251496187	3.09501672309233	3.96400680117389	3.80404099421495	0.000100562088364314
+LYAR	1	-3.94087316663153	0.633825019057501	0.997857564916652	2.11186177869515	2.38306173701129	8.11855466219818e-05
+LOC81691	1	-3.9416525867113	0.20653937771283	0.469882025608552	1.22307067496221	1.72357582133597	8.09221297298406e-05
+EYA3	1	-3.96038226076738	0.937904683456638	1.35977296568482	2.5386410849519	2.74806693326301	7.48298811174074e-05
+GPD1	1	-3.97514720887648	0.0125986006877641	0.197812246309903	0.204381599819505	1.20200784560883	7.03357365339145e-05
+CCBL2	1	-3.98258340770575	1.14356111296857	1.62603089962875	2.8655261328998	3.12530768867703	6.81701887755817e-05
+CTBP2	1	-3.98511816533778	1.07179668761412	1.50851257447525	2.68042087379579	2.82712704961956	6.74465533819417e-05
+MAGED4B	1	-3.98520755838256	0.0595521178568518	0.136548025765079	0.342051296460366	0.498430072598541	6.74211661772755e-05
+C3orf23	1	-4.02081049738194	0.562330132840217	0.943088773830219	2.18992670472531	2.44300131844338	5.79982482145471e-05
+SPIN4	1	-4.02834458191316	0.0268317547653453	0.17477396032571	0.381067775640281	0.947442832475607	5.6170974629302e-05
+TDRD7	1	-4.04186931373928	0.127784281266837	0.375367845357064	1.03647709343901	1.58025466698857	5.30267844800102e-05
+NIM1	1	-4.06949275239809	0.931405211692629	1.39557446838448	2.64826979119549	2.94254851175776	4.71156052254922e-05
+BOLA3-AS1	1	-4.09557116328371	0.257308250764345	0.564432464698574	1.43556560471141	1.93458189842836	4.21128838692946e-05
+DLG2	1	-4.13807708217186	0.37521582049021	0.713632633124568	1.63254080697471	2.10979808068387	3.50228718382247e-05
+POLD1	1	-4.16505546638002	0.247902741813662	0.568706819637836	1.39134398082608	1.98704008879192	3.11276878349063e-05
+ZNF559	1	-4.17964918994931	0.706393874670278	1.15020455348902	2.38729101113891	2.73933694334105	2.91959131643039e-05
+SLC31A1	1	-4.25793821927595	0.680206281918439	1.11859900663016	2.26394676906066	2.65614341754297	2.06320945651865e-05
+MLLT10	1	-4.27142191874225	0.662842683678166	1.08106729382237	2.2640502510061	2.52594942903587	1.94230534390227e-05
+ATP2B2	1	-4.28103242930576	0.131916096538841	0.384528572053305	0.968552066905192	1.52227745503338	1.86028243679262e-05
+TSEN2	1	-4.29607009503723	0.54829295822971	0.952614294463798	2.01946284198775	2.4279673345498	1.73852630674594e-05
+KCNN2	1	-4.30499335513204	0.217079932695588	0.517939163757791	1.25547594040139	1.8029280441539	1.66990747892795e-05
+PCYOX1L	1	-4.34349709114572	0.123183677579292	0.40259020698957	1.0071459916815	1.659527885003	1.4023233528754e-05
+LOC100306951	1	-4.3569685123641	0.388300545136658	0.703754627392452	1.62196620600211	1.86783826834661	1.31876230925407e-05
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+BCL2L1	1	-12.7598279680202	0.566377085487065	2.12704295393215	1.92536936329676	3.15538714411116	2.74807308531392e-37
+NFIC	1	-12.8243737392625	1.48037317042673	3.19015864983816	2.85354517203137	3.43948164944428	1.19750240446686e-37
+PCNP	1	-12.8568230300423	2.42037216598355	4.27701632892615	3.4693988064791	3.7254826820677	7.87471912152743e-38
+AHCYL1	1	-13.5241220227109	3.58284955146472	5.96129036518246	4.48060056748861	4.53702117824738	1.1268089371917e-41
+SSFA2	1	-13.53013904446	1.0611074121322	2.96996899963071	2.61762024941731	3.63965079400452	1.03827073297003e-41
+STARD7	1	-13.8302706386147	2.07388637609222	4.33765949752012	3.72195987321998	4.22269543507408	1.67389552142545e-43
+PFKL	1	-13.8477221864768	1.53162869202527	3.70029562074114	3.2534638185521	4.04019245219207	1.31310353439273e-43
+SEPN1	1	-14.0872760679154	1.19129881582537	3.10002059468282	2.64954638145039	3.49545038252865	4.54767120553209e-45
+SOD2	1	-14.513423409434	2.55939162724971	5.23701043863648	4.25306100632797	4.75955580751029	9.96219299074675e-48
+TUBB3	1	-14.8867376530899	0.790518437506472	3.11799567753424	2.33139873043488	4.03341998888576	4.01907215559785e-50
+EEF2	1	-15.0138403492521	2.53889274033038	4.64451432079819	3.48502895455209	3.6180625264902	5.95950134624977e-51
+MSN	1	-15.0989044449745	1.82633208966343	4.2465710313166	3.44708158442865	4.13523643987058	1.64646269575041e-51
+LANCL2	1	-15.1555583935715	1.32518269562452	3.54424483208848	2.84954365093037	3.77733114352932	6.96211801182061e-52
+NCAM1	1	-15.1782338392848	1.61507039784186	3.95651315159743	3.18616722755748	3.97969549200274	4.92874934521013e-52
+DENND5A	1	-15.2758537506126	2.08771749360766	4.4529342666832	3.59847576330472	3.99441327808131	1.10767782547598e-52
+HNRNPK	1	-15.4094125292037	3.84907788192569	6.19403267975474	4.13302620251809	3.92587015877797	1.41492260717451e-53
+RAB1B	1	-15.479781063864	2.05527287798211	4.21982467408295	3.28104612075655	3.60737014752399	4.75086881104961e-54
+CTDSP2	1	-15.6741242940831	2.1068895390156	4.77079519547426	3.76600170401835	4.38453046518691	2.27336609854861e-55
+EIF4H	1	-16.6706493290774	2.83461623141668	5.43653723239686	3.80381503716743	4.02651321448598	2.14254369816324e-62
+RHOB	1	-16.7214240789665	2.10847653298444	4.71101761989564	3.6539623153526	4.01524335084268	9.15062407635138e-63
+DDR1	1	-18.1520245822287	3.28609440872737	6.21556192475264	4.19299437871249	4.1634289142328	1.23754288410272e-73
+LGALS3BP	1	-18.4115484389792	1.0996028612519	4.2714830406014	2.97882982334641	4.44440877726372	1.06143952049195e-75
+DDR1	2	13.2775003999955	8.29029529222488	6.21556192475264	2.9179941430952	4.1634289142328	3.1265773175008e-40
+AHCYL1	2	12.9052425151356	8.15880507687393	5.96129036518246	3.82101288524656	4.53702117824738	4.20489602145325e-38
+NCAM1	2	11.5979142339317	5.68881891572978	3.95651315159743	3.82719070291657	3.97969549200274	4.22243941541921e-31
+LGALS3BP	2	10.1392202204156	5.96275468263024	4.2714830406014	4.26367131097275	4.44440877726372	3.70041546782833e-24
+CTDSP2	2	10.0568578320466	6.42572743835648	4.77079519547426	4.3013102242027	4.38453046518691	8.56896863457898e-24
+RHOB	2	9.14124861812173	6.08858295870336	4.71101761989564	3.59716965215735	4.01524335084268	6.17353615930923e-20
+LANCL2	2	8.59044054846758	4.7620990663895	3.54424483208848	3.82593437501724	3.77733114352932	8.66364896508449e-18
+DCLK2	2	8.43383347986736	4.42299765122817	3.28595991346018	3.63860779803087	3.59215478912568	3.34522613593308e-17
+DENND5A	2	8.39270251211007	5.7111341500777	4.4529342666832	3.73401695729554	3.99441327808131	4.75092673456653e-17
+LIX1	2	8.35056547527914	2.15870941298123	1.26028656303082	3.52079326563101	2.86661975124951	6.79369194980311e-17
+PGAM2	2	8.31858081707695	2.24766467561673	1.34292360342224	3.43685742406248	2.89787902552362	8.90227897633006e-17
+RUFY3	2	8.14642953537208	4.44873882574499	3.33656991956503	3.67478932195884	3.63754713141573	3.74827006475834e-16
+METTL21B	2	7.99257821852217	2.14323955870708	1.27841167654757	3.59946170498869	2.88302211137892	1.32145617087438e-15
+ATCAY	2	7.91245690602816	1.30834114377942	0.65850184432408	2.97238607160054	2.18826442404855	2.52358238410165e-15
+LOC375010	2	7.81315232651112	0.815172157654363	0.401806902977271	1.93486736635916	1.40965508832916	5.5775121063234e-15
+SEPN1	2	7.61795603050996	4.09941385866487	3.10002059468282	3.59403998229718	3.49545038252865	2.57724051312518e-14
+PER1	2	7.35083806377739	3.58107596090329	2.66113998977203	3.513040952462	3.33446321583541	1.96967934698706e-13
+COL6A1	2	7.27369663141443	2.31847429627419	1.501945952365	3.48282941688735	2.99103342725221	3.49781032787808e-13
+TRIM2	2	7.07801606994692	2.75385750845466	1.91471051768566	3.57502169752916	3.15886948600908	1.46232771800698e-12
+EIF4H	2	7.0213545028636	6.4976092071797	5.43653723239686	3.50793569426194	4.02651321448598	2.19727555381096e-12
+PLXNB1	2	7.01233722989062	2.71747989157921	1.82409262894116	3.89156191843208	3.3945495171133	2.34369452542272e-12
+HNRNPK	2	6.9236979081706	7.21419400954934	6.19403267975474	3.29548944675467	3.92587015877797	4.40003706174875e-12
+TMEM132E	2	6.87019835495781	0.717297419775503	0.331346363814133	2.18825447507092	1.49681505578475	6.4112694842413e-12
+BRP44L	2	6.8614920497312	4.99778817801439	4.03176024246203	3.63171824806509	3.75125257481356	6.81449976440117e-12
+NBPF14	2	6.85893505790913	2.55437261986017	1.91995739606063	2.71806061374546	2.46446179891936	6.93757659604726e-12
+EGFR	2	6.54711662829641	8.73493241401205	7.71710142584918	3.72063797408601	4.14219726022139	5.86585546062346e-11
+PTPRN2	2	6.46441139662755	2.02935292722035	1.33537765780891	3.40344564362483	2.86035668236101	1.01693861370387e-10
+PLEKHB1	2	6.42178351758939	4.60062532102133	3.58038823821959	4.37025555539356	4.23302301012143	1.34686874592295e-10
+TIMP3	2	6.41223139643691	3.43570576604058	2.54960837695085	4.04055995609714	3.68194635077355	1.43404946619207e-10
+SALL1	2	6.1508017084314	3.40738785715155	2.61517805582657	3.66630934661804	3.43173441801784	7.7092254735075e-10
+PCMTD2	2	6.1415153759454	3.26024361324947	2.45827021793916	3.78783095171822	3.47928178338769	8.17379117506678e-10
+AKAP1	2	6.08898220897324	1.2474449460265	0.735166780107847	2.9154721873124	2.241642367875	1.13630744370036e-09
+LINGO1	2	5.97566992832886	0.586083975592056	0.2897099718993	1.82046249227576	1.32147420968444	2.29146541242388e-09
+FSCN1	2	5.8985867128503	2.38005780947543	1.84101305654341	2.51495719393389	2.43490510524178	3.66628276745605e-09
+HUWE1	2	5.87839411773603	4.95409488376572	4.06633579393597	3.96682372647386	4.02384842840634	4.14265653884478e-09
+NFASC	2	5.84469596666518	3.23354566344697	2.45688869796808	3.76296953304197	3.54056443388042	5.07494292956781e-09
+DAAM2	2	5.78547189125629	1.35255677341617	0.824225925551688	3.02664149455376	2.43316951363754	7.23090517843503e-09
+ACADVL	2	5.70428733879929	5.72438976773214	4.82241635398307	4.05112959350116	4.21305887568626	1.16830852650095e-08
+WIPI2	2	5.69330413250293	3.54893670179298	2.77645962622528	3.83492752455461	3.61515066179373	1.24604142575326e-08
+PLEKHA5	2	5.66874395152576	2.51126362500301	1.8448891466254	3.51595956547487	3.13210779266176	1.43848147191933e-08
+NBPF10	2	5.63830599132637	3.005365977649	2.44929538253142	2.72129009925326	2.62776470094296	1.71731153532312e-08
+MARCH6	2	5.60160314123428	4.19986308818508	3.39678213303143	3.93637011373153	3.81990159715167	2.12378354910545e-08
+PFKL	2	5.59811347112118	4.54916049821277	3.70029562074114	3.97990973222549	4.04019245219207	2.16696907882765e-08
+GPT2	2	5.557423472921	3.30423440733769	2.52375008647339	4.04263748300841	3.74193188215017	2.73785956340322e-08
+LOC100499183	2	5.55450623495567	1.6969630920779	1.13072821628388	3.20583878969857	2.71616620910001	2.78397577362176e-08
+SLC20A2	2	5.51792732155055	3.24334703739369	2.48796733869936	3.90140175869355	3.64749342964535	3.43021228553101e-08
+MPRIP	2	5.48933362190438	2.09773459534417	1.50701521065797	3.27052240059277	2.86725805638878	4.03452945679209e-08
+STARD7	2	5.39599867298375	5.19283727622633	4.33765949752012	4.11528000937366	4.22269543507408	6.8143449906317e-08
+NDST1	2	5.37810822806167	3.10054140458964	2.36527968943384	3.97689573975672	3.64265131093934	7.52725654746171e-08
+VAMP5	2	5.35459407913724	2.86233885251824	2.21171903827709	3.51998588896945	3.23747122748596	8.57486970155985e-08
+PURA	2	5.33619429680918	2.15664642426145	1.5923873229177	3.15586653605075	2.81742344350185	9.49176898520911e-08
+SORL1	2	5.24020847396409	3.14549800909239	2.44317703867792	3.85935367132914	3.57101978591624	1.60395291049436e-07
+SSFA2	2	5.21248738879799	3.68200106029179	2.96996899963071	3.80813068256971	3.63965079400452	1.86325238553899e-07
+ATP9A	2	5.20869245102348	2.39214513938838	1.78370411170285	3.45733242701048	3.11239681035548	1.90176032144046e-07
+BOD1L	2	5.18382791216948	2.76527229975023	2.14709712010777	3.37612551119469	3.17735816748594	2.17377517967943e-07
+TBK1	2	5.17611614009184	3.5228507024229	2.76772907492921	4.35950428827456	3.88703169824627	2.26552460427983e-07
+GPR37L1	2	5.06256375169632	4.13749340595622	3.3800754717875	4.24348621312103	3.98630261399991	4.13655671982418e-07
+SLC6A8	2	5.04670703168346	2.42791338308768	1.86738016197459	3.21904010689683	2.9593644226859	4.49489784168368e-07
+TP53BP2	2	5.04025353645633	3.65189060665338	2.94264052950183	3.8646761525089	3.74931728629966	4.64915512743709e-07
+RAB1B	2	5.02733167666938	4.90047343793826	4.21982467408295	3.27369828287579	3.60737014752399	4.97351708849699e-07
+SALL2	2	5.0093847935307	2.51001129914229	1.91731352527918	3.38056447193084	3.15249269180066	5.46043015623045e-07
+IFIT3	2	5.00780345902808	1.57681382117477	1.059998363872	3.29364081700534	2.7497512242036	5.50547093883537e-07
+ATP2B2	2	4.9970404256645	0.670025535138759	0.384528572053305	1.97661040528854	1.52227745503338	5.82168678447728e-07
+CTNNA1	2	4.99294409913663	5.33341221779036	4.55178708900864	4.06713852932155	4.17106535778326	5.94657733971741e-07
+IPO7	2	4.9496224368611	2.23794226434832	1.71665186911127	3.10652276432675	2.80616263099241	7.43575886551685e-07
+CYB5R3	2	4.93235313277488	3.567999067417	2.90006731603596	3.81291781219336	3.60813777083011	8.12448634791166e-07
+BRAT1	2	4.90118168674116	3.32031530002916	2.66455837422494	3.81540053990146	3.564899324041	9.52619035253146e-07
+EEF2	2	4.85666135522152	5.30400506478085	4.64451432079819	3.22327766026443	3.6180625264902	1.19381505236039e-06
+MSN	2	4.79861750329424	4.99132237338928	4.2465710313166	3.98010261193356	4.13523643987058	1.5976456887082e-06
+PHLDA3	2	4.77215097589416	1.94759120223566	1.43044821160384	3.25185681339626	2.88736477018608	1.82268788879265e-06
+TMEM205	2	4.75524729451846	5.45468959554463	4.75029115106727	3.65649258757962	3.94684859347231	1.98203647364967e-06
+PPM1A	2	4.7275098843692	1.61606860761501	1.18066832125834	2.7997083817965	2.45392593313903	2.27290002757203e-06
+TNS3	2	4.71072874669057	1.49602111080153	1.04114285869423	3.01607101839493	2.57283693443468	2.46832581539681e-06
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+ASPH	2	4.6319724027256	3.8700050709553	3.21715306636289	3.81795853988331	3.75538065046214	3.62198442787267e-06
+KAT2B	2	4.61529274769119	2.47578256460763	1.92050048508562	3.41880330459248	3.20567573450808	3.92541597337969e-06
+CNTNAP1	2	4.56548826189528	1.35753914293992	0.972825791556814	2.59375855988035	2.24520093092361	4.98333082231832e-06
+PREPL	2	4.53942911137043	2.88349555545814	2.3034822391873	3.60703519640254	3.40441042297872	5.64067396285078e-06
+SOD2	2	4.53843059500446	6.04772306367896	5.23701043863648	4.51017752993353	4.75955580751029	5.66744426589766e-06
+BRF1	2	4.48976540644311	1.08038302976278	0.74034110589444	2.43465930858366	2.01796672509916	7.13016564467355e-06
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+LOC728875	2	4.36902861158272	0.828908852628566	0.605303987689072	1.62902691297607	1.36364569227322	1.24800416784909e-05
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+SIRPA	2	4.28462881739593	2.57161141706365	2.06653624791957	3.37068460243961	3.14085580775681	1.83044528212246e-05
+ZDHHC8	2	4.27820740725986	1.009238415646	0.708299835272695	2.24484144236271	1.87422280568014	1.88404431917232e-05
+AZIN1	2	4.26444301691621	4.71396245253098	4.06629645335009	3.94710330075237	4.0466343917006	2.00401477949357e-05
+GPD1	2	4.25766017099632	0.389888250210504	0.197812246309903	1.67238817356385	1.20200784560883	2.06577647900545e-05
+DLG2	2	4.24465324676858	1.0497399176759	0.713632633124568	2.50781905509379	2.10979808068387	2.18931705108594e-05
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+BRD4	2	4.20476665054683	2.68227388017908	2.25816305098124	2.78177407204216	2.68746395631962	2.61351655869695e-05
+CRTC1	2	4.18118133672612	1.16272816445707	0.84048820991675	2.37234960256431	2.05345679607853	2.89998464846056e-05
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+CACNA1D	2	4.11525063019902	0.756111923674551	0.487079449811966	2.232229870454	1.74186142144313	3.86758933676626e-05
+CEBPD	2	4.10288094260866	7.09984062814802	6.50292214243738	3.41663312310446	3.87642422790301	4.08037246950782e-05
+CPSF6	2	4.05342967342963	3.2089822599767	2.65391974097395	3.93121078243687	3.64858480654028	5.04721775914326e-05
+LRRC14	2	4.05001602187066	2.75241035669325	2.20895745783206	3.82241117219687	3.57528242373749	5.12141263856728e-05
+MID1IP1	2	4.0408662292635	0.809195238348172	0.604057613276142	1.53762502101314	1.35262071792631	5.32541304250616e-05
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+PLEKHA5	3	3.89946764231416	2.60435285098465	1.8448891466254	3.1292721533268	3.13210779266176	9.64044192808853e-05
+LRIG3	3	3.89847256242869	0.751502901298915	0.372582215414645	2.04490283898695	1.5631074409039	9.68013666115484e-05
+ZNF600	3	3.88573410386264	0.732720760207835	0.368118728296182	1.9906119439173	1.50897138186057	0.000102021124698138
+LOC100499183	3	3.8765711689521	1.78546856559503	1.13072821628388	3.09614291974204	2.71616620910001	0.000105938832594408
+PPM1A	3	3.8660936887539	1.77059607277699	1.18066832125834	2.62260578552727	2.45392593313903	0.000110592468024834
+SPG11	3	3.85920236044298	2.81429951280405	2.04238640526762	3.18092478868178	3.21666520682275	0.000113757712969753
+DDIT4L	3	3.84885727495733	1.19093434040486	0.6849008254465	2.59339064598874	2.11437722644773	0.000118670121502517
+NBPF10	3	3.81008897088265	3.07186309538825	2.44929538253142	2.28853933119745	2.62776470094296	0.000138916790230217
+EXOC7	3	3.80407164259743	2.79168389351898	2.04189188680382	3.24751016481362	3.16976537071849	0.000142336984684626
+BOLA3-AS1	3	3.75729044575689	1.01642044967015	0.564432464698574	2.36674243236318	1.93458189842836	0.000171763097057174
+RHBDL1	3	3.74219581426134	0.648907736911971	0.316821691808842	1.86588847194126	1.42711547393988	0.000182419280135849
+SEC24A	3	3.71893256440997	1.62772532581982	1.06799751432255	2.56055033334474	2.42043587242816	0.000200066450319706
+TDRD7	3	3.71437179309867	0.740354896101516	0.375367845357064	2.10681245274412	1.58025466698857	0.000203709113580602
+ZEB1	3	3.68360737323287	3.65661549017802	2.81005512567054	3.446494397671	3.69589475184142	0.00022995635374639
+ZNF544	3	3.64778266247355	1.52610492781634	0.978607334849696	2.76302379261551	2.41372760330092	0.000264513238593406
+MTX3	3	3.64571323581627	1.12179428594891	0.680642147436548	2.16113017045777	1.94599124292064	0.00026665119924979
+ARHGAP33	3	3.63923805958926	1.28052980585177	0.80092467036672	2.50439490853511	2.11937768209381	0.000273445925496879
+TP53BP1	3	3.63808382369832	2.86431428801422	2.1105997390144	3.35194802172283	3.3317253636435	0.000274674035543733
+RCHY1	3	3.59663993839599	2.09305559947402	1.41771757685026	3.12977128164018	3.01966828068613	0.000322354199623815
+LOC81691	3	3.58576322503071	0.854187883377416	0.469882025608552	2.12122495401292	1.72357582133597	0.000336093801115083
+SLC23A2	3	3.5650533350761	2.36858171859812	1.68467521478781	3.24393188445886	3.08507481213311	0.000363782204398785
+CPSF6	3	3.55109543452337	3.4595797216194	2.65391974097395	3.46137626992176	3.64858480654028	0.00038363128336073
+MDGA1	3	3.51672850722257	0.686388880118536	0.359470309447907	1.87971911874131	1.49498125507126	0.000436900412754687
+ISYNA1	3	3.46508480443322	1.41168604984989	0.890316383634978	2.85778828576596	2.41972989238289	0.000530064302483484
+C2orf72	3	3.4515304654209	1.52627181335247	0.996993948264045	2.79349665964981	2.46607918970912	0.000557416823250995
+CANT1	3	3.42749827977165	1.4675881814556	1.00859596648283	2.16810723217196	2.15359022688097	0.000609170163177974
+MID1IP1	3	3.41803366319762	0.891544058675141	0.604057613276142	1.33077816952238	1.35262071792631	0.000630753050487779
+STX2	3	3.35806983701968	1.98640848967123	1.41308526331391	2.80993505501156	2.74564769283462	0.000784887802118637
+SUSD4	3	3.34498721695196	1.18227683113964	0.730116417205968	2.54710925696096	2.17386751641608	0.00082286362823025
+RAB15	3	3.33332981866309	1.08906430094911	0.661162830316728	2.46840117770992	2.06443155866395	0.000858131507661365
+LMF1	3	3.30924969385766	2.3282568628367	1.70387466793869	3.13661942052856	3.03428220722493	0.000935463693252167
+NEDD4	3	3.29473592324401	0.843827616979287	0.493964387877776	2.08117471826757	1.70770435816441	0.000985142105964779
+COG1	3	3.26053435348684	1.59240837906136	1.05391938056253	2.81312780850227	2.65596930936771	0.0011120249544311
+WASH3P	3	3.19199979273016	1.8531217877632	1.48088514896608	1.47886861857167	1.87538855462554	0.0014129143407386
+SMAD5	3	3.18641496950842	3.58523593784994	2.93258924523917	2.83657670878212	3.29390299818345	0.00144047823575367
+ATP6V0C	3	3.18154690251332	4.31001062683676	3.86757641424506	1.29161379164314	2.23637881955919	0.00146490800857425
+EGFR	3	3.15221562610108	8.52901854201951	7.71710142584918	3.00302131474918	4.14219726022139	0.00162036568022208
+EFR3A	3	3.14710842119686	1.28091269645746	0.83931863074403	2.49011402545519	2.2565581070256	0.0016489380585544
+KCNN2	3	3.14606425447586	0.87064365080968	0.517939163757791	2.14356967867921	1.8029280441539	0.00165483645609734
+NIM1	3	3.14167250843082	1.97041786316381	1.39557446838448	3.18493776829878	2.94254851175776	0.00167985816355017
+PDGFD	3	3.09783486227228	0.661196421351377	0.349302354832403	1.93731412857987	1.61913793339792	0.00194940022231686
+CRTC2	3	3.06975285269127	1.41561938703312	0.993426452446323	2.21512030273215	2.21178316035361	0.00214235973368859
+IFIH1	3	3.05680604546444	0.905901562910241	0.544017857768751	2.28610577820889	1.90386496621516	0.00223708977709309
+TP53BP2	3	3.04958402028583	3.65362120992726	2.94264052950183	3.50786122295216	3.74931728629966	0.00229158524097742
+KIF2A	3	3.02923520427062	2.63544284395239	2.05498257380701	3.01987002528367	3.081587487209	0.00245173724411986
+PER1	3	2.99035943768413	3.2811723069616	2.66113998977203	2.91557953418825	3.33446321583541	0.00278649342543612
+PPP1R26	3	2.95849024571516	0.861567620604585	0.520444320262239	2.23600921764159	1.85428395662307	0.0030915002565192
+C15orf40	3	2.91458169596334	1.77698299232058	1.28799010778606	2.7216957432192	2.69812026727689	0.00356165575077613
+TRAPPC9	3	2.87146962876204	1.09053380101418	0.719748948006064	2.26478633411007	2.07659954710795	0.00408568040423767
+NAIF1	3	2.85170290445881	0.489390274559966	0.261360429304809	1.59232144814671	1.2859450536684	0.00434857230037234
+UBAP2	3	2.8515450857114	1.83158797011716	1.35439049809188	2.76085810075492	2.69124285256706	0.00435073158323015
+TNS3	3	2.84639671806792	1.49652153873656	1.04114285869423	2.84691305494558	2.57283693443468	0.00442170702226076
+INVS	3	2.83373123150818	1.03443833765753	0.667892942896287	2.41282809000218	2.0801952887827	0.0046008009069649
+BEND6	3	2.83187637468941	1.09867479433899	0.752440082164136	2.20534778114332	1.96621639827434	0.00462757363466817
+ZNF692	3	2.81217869041635	1.78105315507786	1.2919283640973	2.85954541717742	2.79712426030006	0.00492071585508756
+HIATL2	3	2.73303013070158	1.49343101400091	1.08652918217594	2.42499281917397	2.39430913807385	0.00627545912040462
+SNX29	3	2.72790780443631	1.49382311900739	1.06157388310574	2.73629205001439	2.5482353942391	0.00637374194395898
+DNASE1	3	2.72263861915081	0.537757847714682	0.306870958958617	1.64663014956565	1.36377984821377	0.00647628574944319
+GCAT	3	2.71922347633729	0.977274058028152	0.627391378737235	2.36442808234382	2.06924798141462	0.00654353820062001
+GGNBP2	3	2.70332255833553	3.14985250869939	2.54163127541327	3.55534869914798	3.61825113273262	0.00686500908840569
+NSUN5P1	3	2.69682636650249	2.01267595063984	1.55711459482343	2.66653349909927	2.71661997037286	0.00700037615076175
+RNF44	3	2.68319840911527	1.21170341044365	0.86112241651899	2.23046663675518	2.10121541342855	0.00729217136434974
+ZNF815	3	2.66551274168236	0.452211541251628	0.246326932456439	1.52174246897462	1.24216164846543	0.00768710186150414
+RPS29	3	2.65317482381329	4.49282777120119	4.10483867741957	1.69926249263026	2.35173643708298	0.00797385595624718
+SPIN3	3	2.63780198107305	0.856367343406465	0.539784681986102	2.22323068318797	1.93010054512115	0.00834452924184011
+ZBTB41	3	2.61287579168483	1.36226045674692	0.983769839671932	2.38224614969819	2.32954631975061	0.00897839256909747
+F8	3	2.59315262713844	0.738520211739456	0.45450955360202	1.95030047783211	1.76133334387751	0.00951005558539623
+ZDHHC8	3	2.58213380716349	1.00922947431666	0.708299835272695	1.91567471568563	1.87422280568014	0.00981915060894223
+NR2C2	3	2.51560996881201	1.55284894226981	1.15444994122998	2.5198782011432	2.54688849405328	0.0118826600820703
+C17orf80	3	2.49783720160962	1.2676102619043	0.890921154292548	2.66295482706281	2.42523557698211	0.012495356302522
+CNTNAP1	3	2.49173376300265	1.32069969696942	0.972825791556814	2.31502330549348	2.24520093092361	0.0127121285066929
+DCXR	3	2.47550220438825	3.6297648523691	3.05188462552362	3.42857622303714	3.75413179269388	0.0133048940379592
+APBB2	3	2.47265716089419	1.98541489493616	1.52250967335125	3.0029972944338	3.01067012234566	0.0134112731104879
+RPAP3	3	2.45538760653997	2.22798666927388	1.76725140318432	2.89171327934094	3.01763281678623	0.0140732753097878
+ZNF324	3	2.44575617979165	1.09211643868351	0.747820027234708	2.5416224080605	2.2638848559232	0.0144548716474658
+PLA2G4C	3	2.35768114027564	1.21197354246347	0.867239574294197	2.58217674389575	2.35144056895433	0.0183894810163512
+SNORD116-26	3	2.34144110527238	0.677360532889093	0.462953397156306	1.4736041746712	1.4726210173554	0.0192094564296264
+PURA	3	2.33984245198591	2.00231169721885	1.5923873229177	2.72908784915913	2.81742344350185	0.0192918760907383
+PROX1	3	2.30573374212494	0.904407109050696	0.627549643425384	2.20216728519254	1.93099914571308	0.0211255144920769
+ZNF318	3	2.30470836962694	1.4046417827161	1.04739691705104	2.69564746964203	2.49278610123783	0.0211829118352662
+ABHD10	3	2.28925679737444	1.35791956909366	1.00257720348008	2.58413218047867	2.49624653224482	0.0220644362795714
+ZCCHC10	3	2.2617450230811	1.8374729881288	1.45564531061548	2.58684101169424	2.71493077358942	0.0237131612953493
+UBC	3	2.25861086904349	10.199123294983	9.89779819432538	1.1924344752747	2.14550185456567	0.0239076011193729
+ABHD14A	3	2.25092529523756	1.85930891025519	1.45010520618288	2.91609188531195	2.92356983533123	0.0243902693214787
+ATP9A	3	2.21167720594212	2.21174150036122	1.78370411170285	2.96526675164315	3.11239681035548	0.0269889765668308
+TAOK1	3	2.20561776702191	2.96838445203296	2.50157301152567	3.11764753699973	3.40366052093886	0.0274107740106817
+MPRIP	3	2.18146678933266	1.89595322230729	1.50701521065797	2.90832836339302	2.86725805638878	0.0291489082756688
+IFIT3	3	2.12494948756903	1.42333318132789	1.059998363872	2.86995290162841	2.7497512242036	0.0335908279798883
+ZBTB44	3	2.0648714122832	1.34157329737872	1.04281214425939	2.2813716044497	2.3268378145973	0.0389351686672935
+FMR1	3	2.03927660722753	1.40709805780491	1.09504869907744	2.39214834301331	2.46083307155157	0.0414224289619749
+CRTC1	3	2.02683228997934	1.09929066192707	0.84048820991675	2.09957016758003	2.05345679607853	0.0426795670039792
+ZNF620	3	2.00175705849305	0.610234171109308	0.403867056232137	1.87115912123137	1.65792210375095	0.0453108663987654
+SLC25A48	3	1.99867920952652	0.555404246539908	0.357665097651329	1.82896700629076	1.59105269424238	0.045643073902365
+RNF122	3	-2.0956836057342	0.207919722253637	0.391816920198538	0.9220080255968	1.41118643658678	0.0361102671194758
+STOX2	3	-2.19837583022204	0.311954402899588	0.575761068032365	1.35769659846036	1.92982896728664	0.0279223346194849
+ATCAY	3	-2.70854244192597	0.289948422856921	0.65850184432408	1.46763649046978	2.18826442404855	0.00675794679385771
+LOC375010	3	-3.26590633027169	0.115533111362415	0.401806902977271	0.699330003525432	1.40965508832916	0.00109114336284898
+BCAN	3	-4.23401281992115	5.44882445044115	6.77485459849344	4.82671858168806	5.03658568935348	2.29557849307747e-05
+TM4SF1	3	-4.62467151486852	0.609115077382501	1.64679530949995	2.12687733525997	3.60842472917828	3.75192516101887e-06
+TUSC3	3	-4.83329925725252	0.0354284526248365	0.820349274023337	0.508493955333197	2.61166315266037	1.34288685697392e-06
diff -r 8e17c31c536a -r 569334568afa test-data/hcpc.cluster_description.tab
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/hcpc.cluster_description.tab	Mon Sep 02 04:39:20 2019 -0400
@@ -0,0 +1,1180 @@
+genes	cluster_id	v.test	Mean in category	Overall mean	sd in category	Overall sd	p.value
+TUSC3	1	11.8890897711964	2.02149769035256	0.820349274023337	3.81496317321131	2.61166315266037	1.34868362907211e-32
+USMG5	1	8.61018275981449	5.36922025791415	4.36307228245837	3.30870030072204	3.02077642160404	7.29441907532539e-18
+TM4SF1	1	6.8501233340706	2.60299136171499	1.64679530949995	4.48210676849274	3.60842472917828	7.37863458923549e-12
+WASF3	1	3.81082062029984	2.72810637690025	2.23304493116436	3.8140236890506	3.35822425701289	0.000138506246351441
+RPS29	1	3.69248178150784	4.44076026507806	4.10483867741957	2.71626848553352	2.35173643708298	0.000222076254209972
+ATP6V0C	1	2.85728617185022	4.1147659118381	3.86757641424506	2.68387039140677	2.23637881955919	0.00427280416431219
+RPS6	1	2.28645686432482	8.05369460415472	7.77324497980439	3.51400575835216	3.1707422903076	0.0222275449023515
+ADD3	1	-2.03898945313383	2.67200952180054	2.97075160954821	3.99658342916655	3.78748156266524	0.04145108017794
+ZNF620	1	-2.09339320365175	0.269607305499926	0.403867056232137	1.45402896093331	1.65792210375095	0.0363140686205794
+AGMO	1	-2.16542265853872	0.550187878554447	0.736036212379138	2.0807096254801	2.21863106726791	0.030355332385656
+ZNF815	1	-2.33839574702057	0.133962973147947	0.246326932456439	1.01648773391031	1.24216164846543	0.0193667281609244
+SNORD116-26	1	-2.40369126298929	0.326022774081065	0.462953397156306	1.3861980093835	1.4726210173554	0.0162304741865377
+ELP4	1	-2.40849812960999	0.974148047514188	1.23114458089402	2.6360911416134	2.75835428689567	0.0160183083673185
+APBB2	1	-2.41667816437009	1.24105212802172	1.52250967335125	2.87073537301846	3.01067012234566	0.0156628589394647
+RYK	1	-2.47171547161999	0.824118979184263	1.06171807888193	2.36953231938935	2.48493715467498	0.0134466490391557
+PRADC1	1	-2.48046576244539	1.14207696618551	1.42011297473606	2.86710513825962	2.89758979425945	0.0131210864071634
+ABHD10	1	-2.5790613250417	0.75353092955207	1.00257720348008	2.32308715173801	2.49624653224482	0.00990691975234645
+TTC14	1	-2.58582678155596	1.39510160792198	1.71612883234859	3.17313325553508	3.20930896865728	0.00971457375210226
+MTBP	1	-2.60912344768115	0.385579544987324	0.579164139504745	1.73636076126248	1.9179852388187	0.00907744888585606
+MYH10	1	-2.61011059239789	1.75799766282434	2.10139225838514	3.41282879858192	3.40097658353322	0.00905129559470747
+C15orf40	1	-2.62147658919973	1.01437618484177	1.28799010778606	2.68426853335147	2.69812026727689	0.00875497751214468
+CMTM6	1	-2.63702536521193	2.26464501565307	2.64201520918745	3.88129677814107	3.69932410486321	0.00836365773852664
+MBTPS2	1	-2.64835122516919	0.874222046215456	1.14554924298665	2.56566099582828	2.64841989757772	0.00808854422244584
+CHEK1	1	-2.7265321223624	0.828111216691287	1.09603981908161	2.40734450237589	2.54025640477418	0.00640037224572248
+ATP1A3	1	-2.73870881202368	0.162426144112341	0.289113068628839	0.90568885226386	1.19579030792616	0.00616809771090977
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+CCDC106	1	-9.16774221151852	0.223425612034753	0.926589742260221	1.18375754262997	1.98272923670122	4.83029496198285e-20
+C21orf62	1	-9.17362434424983	1.21737413572237	2.52565523543267	3.0517572499778	3.68662709269664	4.5737679879861e-20
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+EGFR	1	-9.34283021755064	6.22003821252729	7.71710142584918	4.59808751235825	4.14219726022139	9.37927828162916e-21
+LPAR1	1	-9.35298796880943	0.481133149160073	1.57594858814207	1.87865467178306	3.02593526311617	8.52059356029654e-21
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+FAM108A1	1	-9.61445379927585	0.304960604127183	1.11754248677865	1.27497044591767	2.18479962823475	6.94771037803728e-22
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+TMEM175	1	-9.83520302094011	0.665905087639984	1.8527681831903	2.17903891265214	3.11951006996609	7.94072843095435e-23
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+LIMS1	1	-10.1354368993947	0.472796960904102	1.59089516958538	1.7485573195348	2.85171797127177	3.84650192314296e-24
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+CEBPD	1	-10.2902020932638	4.95985043524275	6.50292214243738	4.37558858432429	3.87642422790301	7.80124652888634e-25
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+MARCH6	1	-11.0778329723004	1.75982278978184	3.39678213303143	3.29293113006724	3.81990159715167	1.60715324518031e-28
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+AKAP1	2	6.29684256358971	1.28678126972463	0.735166780107847	2.9482051560427	2.241642367875	3.03769523000442e-10
+DAAM2	2	6.2657688185163	1.42001596411024	0.824225925551688	3.08571731228972	2.43316951363754	3.70990389977272e-10
+EIF4H	2	6.15376546251247	6.40485203943977	5.43653723239686	3.5534187057435	4.02651321448598	7.56645573079623e-10
+MPRIP	2	6.12283104747436	2.19308068063464	1.50701521065797	3.3157269105948	2.86725805638878	9.19271565671746e-10
+NBPF10	2	6.06819755799831	3.07244551253248	2.44929538253142	2.72971812662251	2.62776470094296	1.29353729726962e-09
+SALL1	2	5.99798169164834	3.41956555072117	2.61517805582657	3.65739566154891	3.43173441801784	1.99785038789429e-09
+HUWE1	2	5.91799802376473	4.99693554751646	4.06633579393597	3.9730075092449	4.02384842840634	3.2588388290907e-09
+PLEKHA5	2	5.74501354971459	2.54808169761556	1.8448891466254	3.53306268116533	3.13210779266176	9.19136259475384e-09
+FSCN1	2	5.68511547477544	2.38197639656285	1.84101305654341	2.50744751934529	2.43490510524178	1.30724300076016e-08
+ACADVL	2	5.66015662341732	5.75432315507797	4.82241635398307	4.05181477765117	4.21305887568626	1.51234905075244e-08
+TBK1	2	5.60488539952672	3.61912452247427	2.76772907492921	4.41500477613679	3.88703169824627	2.08392800387246e-08
+LOC100499183	2	5.54704577026862	1.71952387005311	1.13072821628388	3.23501029693642	2.71616620910001	2.90536706152126e-08
+ATP2B2	2	5.46938586068462	0.709899602914994	0.384528572053305	2.03453538447739	1.52227745503338	4.51597631834768e-08
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+PURA	2	5.38992194622846	2.1858331825832	1.5923873229177	3.18685312629399	2.81742344350185	7.04882922131438e-08
+NFASC	2	5.372938230473	3.20030290146773	2.45688869796808	3.76419367428999	3.54056443388042	7.74638710101129e-08
+ATP9A	2	5.33179968975283	2.43221204135925	1.78370411170285	3.48425877711304	3.11239681035548	9.72441723123928e-08
+IFIT3	2	5.27007917697468	1.62631203817538	1.059998363872	3.34422944952306	2.7497512242036	1.36364923282607e-07
+NDST1	2	5.23177989857963	3.11003493351795	2.36527968943384	3.96784807096362	3.64265131093934	1.67885581685e-07
+BOD1L	2	5.22899477528822	2.79637541597322	2.14709712010777	3.39468996148144	3.17735816748594	1.704341812523e-07
+MARCH6	2	5.20440520781539	4.17369047084998	3.39678213303143	3.91635344821226	3.81990159715167	1.94618934120241e-07
+STARD7	2	5.17465578100862	5.19158056562615	4.33765949752012	4.14229507999952	4.22269543507408	2.2833153607343e-07
+SALL2	2	5.09257478467666	2.54470412597207	1.91731352527918	3.40891609908453	3.15249269180066	3.53233312235147e-07
+IPO7	2	5.05690669055179	2.27120642975921	1.71665186911127	3.1394320840439	2.80616263099241	4.26111595317915e-07
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+BAZ2B	2	4.99703121053299	4.23700474731504	3.46955435390984	4.00601806803014	3.92999272916627	5.82196488083876e-07
+SLC6A8	2	4.98448632673817	2.44383509712112	1.86738016197459	3.2489075522143	2.9593644226859	6.21266387757261e-07
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+SSFA2	2	4.77896231176701	3.64970430396839	2.96996899963071	3.80912114560675	3.63965079400452	1.76202215671622e-06
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+EXOC7	2	4.52704874577892	2.60266707725177	2.04189188680382	3.37125581372094	3.16976537071849	5.98131466510442e-06
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+PREPL	2	4.42817525976075	2.89261505829966	2.3034822391873	3.61506295261112	3.40441042297872	9.50336677910856e-06
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+TMEM205	2	4.00338873409683	5.36777376430924	4.75029115106727	3.69707930430913	3.94684859347231	6.24415749719815e-05
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+INVS	3	2.81464201777486	1.01229836035984	0.667892942896287	2.38735778553264	2.0801952887827	0.00488315960598279
+GCAT	3	2.81232409053179	0.969702182641018	0.627391378737235	2.36946751519224	2.06924798141462	0.0049184918290788
+EGFR	3	2.78058338555937	8.39460158204196	7.71710142584918	3.17694650176996	4.14219726022139	0.00542613224900927
+NEDD4	3	2.77668962066377	0.772886357144745	0.493964387877776	2.00548819256047	1.70770435816441	0.00549155920161329
+ZDHHC8	3	2.74567349492216	1.01100010543135	0.708299835272695	1.98732298259298	1.87422280568014	0.00603868287585738
+DNASE1	3	2.70559856028135	0.523916229608503	0.306870958958617	1.64201098571102	1.36377984821377	0.00681814122609724
+KIF2A	3	2.6463606255485	2.53467871766827	2.05498257380701	3.00759970436805	3.081587487209	0.00813630258248117
+ZBTB41	3	2.57867602839635	1.33712450721546	0.983769839671932	2.3709669949579	2.32954631975061	0.00991797538899024
+DCXR	3	2.54761690045454	3.61446727666374	3.05188462552362	3.44140911577688	3.75413179269388	0.0108461506916675
+PURA	3	2.53034996148512	2.01173613183149	1.5923873229177	2.73945441941402	2.81742344350185	0.0113948808379534
+ZNF318	3	2.52788130909517	1.41806431767562	1.04739691705104	2.68601833240926	2.49278610123783	0.0114753138555842
+SPIN3	3	2.52127351041374	0.826032769331802	0.539784681986102	2.19129920944963	1.93010054512115	0.0116930924061049
+ZFP3	3	2.50996027529352	0.944483554475497	0.639565939142642	2.30640666404979	2.06525160076458	0.0120744743900702
+UBC	3	2.47749838299675	10.2104673012134	9.89779819432538	1.1769177759777	2.14550185456567	0.0132307008319063
+ZNF324	3	2.45587054656597	1.07486125464565	0.747820027234708	2.54600566666199	2.2638848559232	0.0140543775366523
+RPS29	3	2.44917864597179	4.44364523806832	4.10483867741957	1.72217422210877	2.35173643708298	0.0143182412584298
+BEND6	3	2.42375389073421	1.03276553487288	0.752440082164136	2.15682007582587	1.96621639827434	0.0153610116112423
+GGNBP2	3	2.39744927102114	3.05189046193646	2.54163127541327	3.53444717784852	3.61825113273262	0.0165096668830714
+RPAP3	3	2.39531204971289	2.1924298023185	1.76725140318432	2.88844375807008	3.01763281678623	0.0166062255938789
+SNX29	3	2.3874651841541	1.41943893615208	1.06157388310574	2.68164674065677	2.5482353942391	0.0169650095572576
+NR2C2	3	2.38562109453754	1.51184956984908	1.15444994122998	2.4892362738085	2.54688849405328	0.0170503080032895
+CNTNAP1	3	2.37819683198808	1.28690971618738	0.972825791556814	2.30939870708895	2.24520093092361	0.0173975364339062
+PER1	3	2.34477399114092	3.12104656444108	2.66113998977203	2.93185803988654	3.33446321583541	0.0190386163231545
+ZNF815	3	2.29743937061733	0.414193756810119	0.246326932456439	1.46176746288646	1.24216164846543	0.0215937180056699
+ABHD10	3	2.24533311965586	1.3322711370725	1.00257720348008	2.56434812404649	2.49624653224482	0.0247467553845599
+C17orf80	3	2.2163795970127	1.20710579778302	0.890921154292548	2.59799496245609	2.42523557698211	0.0266655158231351
+TRIM2	3	2.17484097110458	2.31882264875011	1.91471051768566	2.96834324870494	3.15886948600908	0.0296420356384355
+ABHD14A	3	2.16757904470942	1.82286676157307	1.45010520618288	2.91186926749266	2.92356983533123	0.0301907295651873
+SNORD116-26	3	2.16181060992185	0.650216121617399	0.462953397156306	1.44461640746217	1.4726210173554	0.0306327773405748
+KCNC4	3	2.14343973949296	0.292558403981425	0.164064559520356	1.35142690215557	1.01912708938708	0.0320778049876396
+HRASLS	3	2.10768077799917	0.931853774366771	0.672637228800667	2.23547120645236	2.09081296655755	0.0350586110828418
+ATP9A	3	2.0338138604152	2.15605197279304	1.78370411170285	2.95820104057958	3.11239681035548	0.041970366521337
+NAB1	3	2.02671137429921	1.43403970481113	1.12708657781216	2.66855824747581	2.57476417637419	0.0426919385611801
+PROX1	3	1.99444661432834	0.854090843476411	0.627549643425384	2.1473310415848	1.93099914571308	0.0461032686442205
+CCDC163P	3	1.99023702369186	0.724362321144492	0.509243236341225	1.99708110508895	1.83751732036673	0.0465648316478792
+HTT	3	1.97251474332772	2.02575312872827	1.66910845650959	2.94451447212473	3.0737800216287	0.0485508749431717
+APBB2	3	1.9698610893451	1.87136187924366	1.52250967335125	2.91641413464314	3.01067012234566	0.0488542929526014
+ZCCHC10	3	1.96146943257803	1.76888948573471	1.45564531061548	2.54082931423614	2.71493077358942	0.0498242873934793
+RUFY3	3	-1.96556424613337	2.91599964696109	3.33656991956503	3.0368084988776	3.63754713141573	0.049348967556493
+DAAM2	3	-2.08383214167104	0.525977748461017	0.824225925551688	1.84000134978044	2.43316951363754	0.0371754385745041
+STOX2	3	-2.41400357335001	0.30173023636278	0.575761068032365	1.32073203594924	1.92982896728664	0.0157783076180194
+ATCAY	3	-3.05261662545276	0.265572228014968	0.65850184432408	1.40689219170703	2.18826442404855	0.00226855558993392
+LOC375010	3	-3.56957664125158	0.105820150672655	0.401806902977271	0.670055528133466	1.40965508832916	0.000357558601448744
+BCAN	3	-4.24738714298154	5.51650656602858	6.77485459849344	4.85131015504388	5.03658568935348	2.16278049005184e-05
+TUSC3	3	-5.12874214201938	0.0324499543953149	0.820349274023337	0.486749315929723	2.61166315266037	2.91684545621196e-07
+TM4SF1	3	-5.13006974665495	0.557906287691052	1.64679530949995	2.04251649806878	3.60842472917828	2.89634843069756e-07