Mercurial > repos > artbio > small_rna_signatures
comparison signature.xml @ 7:07771982ef9b draft
planemo upload for repository https://github.com/ARTbio/tools-artbio/tree/master/tools/small_rna_signatures commit 7276b6b73aef7af4058ad2c1e34c4557e9cccbe0
author | artbio |
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date | Sun, 10 Sep 2017 13:50:40 -0400 |
parents | a35e6f9c1d34 |
children | 59ee49bfb7bb |
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6:4da23f009c9e | 7:07771982ef9b |
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1 <tool id="signature" name="Small RNA Signatures" version="3.0.0"> | 1 <tool id="signature" name="Small RNA Signatures" version="3.1.0"> |
2 <description /> | 2 <description /> |
3 <requirements> | 3 <requirements> |
4 <requirement type="package" version="1.11.2=py27_0">numpy</requirement> | 4 <requirement type="package" version="1.11.2=py27_0">numpy</requirement> |
5 <requirement type="package" version="0.11.2.1=py27_0">pysam</requirement> | 5 <requirement type="package" version="0.11.2.1=py27_0">pysam</requirement> |
6 <requirement type="package" version="1.3.2=r3.3.1_0">r-optparse</requirement> | 6 <requirement type="package" version="1.3.2=r3.3.1_0">r-optparse</requirement> |
87 | 87 |
88 **What it does** | 88 **What it does** |
89 | 89 |
90 Compute small RNA (piRNA, siRNA, ...) signatures. | 90 Compute small RNA (piRNA, siRNA, ...) signatures. |
91 | 91 |
92 This tool computes (i) the number of pairs by overlap classes (in nt) and associated the z-scores, | 92 This tool computes (i) the number of pairs **aligned** reads by overlap classes (in nt) and associated the z-scores, |
93 and (ii) the ping-pong signal (`Brennecke et al, 2009`_) and associated z-scores. | 93 and (ii) the ping-pong signal (`Brennecke et al, 2009`_) and associated z-scores. |
94 | |
95 **Note** that the number of pairs of aligned reads is disctint from the number of pairs of reads | |
96 when these reads can be aligned at multiple positions in the genome. The two values are equal only | |
97 when the analysis is restricted to uniquely mapping reads. | |
98 | |
94 Options set the min and max size of both the query small rna class and the target small rna class, | 99 Options set the min and max size of both the query small rna class and the target small rna class, |
95 the range over which to compute the signatures, and whether the signatures should be reported at | 100 the range over which to compute the signatures, and whether the signatures should be reported at |
96 genome-wide level or by item (chromosomes, genes, etc.). For details on computational algorithmes | 101 genome-wide level or by item (chromosomes, genes, etc.). For details on computational algorithmes |
97 for piRNA and siRNA signatures, see `Antoniewski (2014)`_. | 102 for piRNA and siRNA signatures, see `Antoniewski (2014)`_. |
98 | 103 |