Mercurial > repos > bgruening > pharmcat
diff test-data/test_3.json @ 1:891283e0ee89 draft default tip
"planemo upload for repository https://github.com/bgruening/galaxytools/tree/master/tools/pharmcat commit dddf99b20ed9b07334505917f362785e3dace3b9"
| author | bgruening |
|---|---|
| date | Thu, 05 May 2022 20:27:17 +0000 |
| parents | d67642a21a1d |
| children |
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--- a/test-data/test_3.json Fri Jan 28 21:18:23 2022 +0000 +++ b/test-data/test_3.json Thu May 05 20:27:17 2022 +0000 @@ -1,5 +1,85 @@ [ { + "geneSymbol": "ABCG2", + "chr": "chr4", + "phased": true, + "callSource": "MATCHER", + "uncalledHaplotypes": [ + "rs2231142 reference (G)", + "rs2231142 variant (T)" + ], + "messages": [], + "relatedDrugs": [], + "matcherDiplotypes": [ + { + "allele1": { + "gene": "ABCG2", + "name": "Unknown", + "function": "Unassigned function", + "reference": false + }, + "allele2": { + "gene": "ABCG2", + "name": "Unknown", + "function": "Unassigned function", + "reference": false + }, + "gene": "ABCG2", + "phenotypes": [ + "No Result" + ], + "variant": null, + "lookupKey": [ + "No Result" + ], + "label": "Unknown/Unknown" + } + ], + "diplotypes": [ + { + "allele1": { + "gene": "ABCG2", + "name": "Unknown", + "function": "Unassigned function", + "reference": false + }, + "allele2": { + "gene": "ABCG2", + "name": "Unknown", + "function": "Unassigned function", + "reference": false + }, + "gene": "ABCG2", + "phenotypes": [ + "No Result" + ], + "variant": null, + "lookupKey": [ + "No Result" + ], + "label": "Unknown/Unknown" + } + ], + "variants": [ + { + "gene": "ABCG2", + "chromosome": "chr4", + "position": 88131171, + "dbSnpId": "rs2231142", + "call": null, + "alleles": [ + "rs2231142 variant (T)" + ], + "phased": false, + "wildtypeAllele": "G", + "mismatch": false, + "warnings": [] + } + ], + "variantsOfInterest": [], + "highlightedVariants": [] + }, + { "geneSymbol": "CACNA1S", "chr": "chr1", "phased": true, @@ -22,9 +102,13 @@ "reference": true }, "gene": "CACNA1S", - "phenotype": "Uncertain Susceptibility", + "phenotypes": [ + "Uncertain Susceptibility" + ], "variant": null, - "lookupKey": "Uncertain Susceptibility", + "lookupKey": [ + "Uncertain Susceptibility" + ], "label": "Reference/Reference" } ], @@ -43,9 +127,13 @@ "reference": true }, "gene": "CACNA1S", - "phenotype": "Uncertain Susceptibility", + "phenotypes": [ + "Uncertain Susceptibility" + ], "variant": null, - "lookupKey": "Uncertain Susceptibility", + "lookupKey": [ + "Uncertain Susceptibility" + ], "label": "Reference/Reference" } ], @@ -61,7 +149,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CACNA1S", @@ -74,7 +163,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -103,9 +193,13 @@ "reference": true }, "gene": "CFTR", - "phenotype": "ivacaftor non-responsive in CF patients", + "phenotypes": [ + "ivacaftor non-responsive in CF patients" + ], "variant": null, - "lookupKey": "ivacaftor non-responsive in CF patients", + "lookupKey": [ + "ivacaftor non-responsive in CF patients" + ], "label": "No CPIC variants found" } ], @@ -124,9 +218,13 @@ "reference": true }, "gene": "CFTR", - "phenotype": "ivacaftor non-responsive in CF patients", + "phenotypes": [ + "ivacaftor non-responsive in CF patients" + ], "variant": null, - "lookupKey": "ivacaftor non-responsive in CF patients", + "lookupKey": [ + "ivacaftor non-responsive in CF patients" + ], "label": "No CPIC variants found" } ], @@ -142,7 +240,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -155,7 +254,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -168,7 +268,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -181,7 +282,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -194,7 +296,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -207,7 +310,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -220,7 +324,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -233,7 +338,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -246,7 +352,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -259,7 +366,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -272,7 +380,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -285,7 +394,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -298,7 +408,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -311,7 +422,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -324,7 +436,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -337,7 +450,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -350,7 +464,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -363,7 +478,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -376,7 +492,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -389,7 +506,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -402,7 +520,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -415,7 +534,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -428,7 +548,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -441,7 +562,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -454,7 +576,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -467,7 +590,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -480,7 +604,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -493,7 +618,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -506,7 +632,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -519,7 +646,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -532,7 +660,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -545,7 +674,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -558,7 +688,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -571,7 +702,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -584,7 +716,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -597,7 +730,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -610,7 +744,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -623,7 +758,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CFTR", @@ -636,7 +772,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -665,9 +802,13 @@ "reference": true }, "gene": "CYP2B6", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*1/*1" } ], @@ -686,9 +827,13 @@ "reference": true }, "gene": "CYP2B6", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*1/*1" } ], @@ -707,7 +852,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -720,7 +866,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -734,7 +881,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -747,7 +895,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -760,7 +909,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -773,7 +923,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -786,7 +937,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -799,7 +951,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -812,7 +965,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -825,7 +979,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -838,7 +993,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -851,7 +1007,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -865,7 +1022,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -878,7 +1036,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -891,7 +1050,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -904,7 +1064,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -917,7 +1078,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -940,7 +1102,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -953,7 +1116,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -967,7 +1131,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -980,7 +1145,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1004,7 +1170,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1017,7 +1184,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1030,7 +1198,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1043,7 +1212,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1056,7 +1226,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1069,7 +1240,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1082,7 +1254,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1095,7 +1268,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1108,7 +1282,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1121,7 +1296,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1134,7 +1310,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1147,7 +1324,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1160,7 +1338,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2B6", @@ -1176,7 +1355,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -1205,9 +1385,13 @@ "reference": true }, "gene": "CYP2C19", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*38/*38" } ], @@ -1226,9 +1410,13 @@ "reference": true }, "gene": "CYP2C19", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*38/*38" } ], @@ -1245,7 +1433,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1258,7 +1447,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1271,7 +1461,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1284,7 +1475,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1297,7 +1489,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1313,7 +1506,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1326,7 +1520,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1339,7 +1534,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1352,7 +1548,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1365,7 +1562,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1378,7 +1576,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1391,7 +1590,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1405,7 +1605,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1418,7 +1619,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1431,7 +1633,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1444,7 +1647,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1457,7 +1661,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1471,7 +1676,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1484,7 +1690,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1497,7 +1704,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1510,7 +1718,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1523,7 +1732,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1536,7 +1746,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1549,7 +1760,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1562,7 +1774,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1575,7 +1788,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1615,7 +1829,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1628,7 +1843,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1641,7 +1857,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1654,7 +1871,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1667,7 +1885,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1680,7 +1899,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1693,7 +1913,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C19", @@ -1706,7 +1927,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -1721,7 +1943,17 @@ "*72", "*73", "*74", - "*75" + "*75", + "*76", + "*77", + "*78", + "*79", + "*80", + "*81", + "*82", + "*83", + "*84", + "*85" ], "messages": [], "relatedDrugs": [], @@ -1740,9 +1972,13 @@ "reference": true }, "gene": "CYP2C9", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "2", + "lookupKey": [ + "2" + ], "label": "*1/*1" } ], @@ -1761,9 +1997,13 @@ "reference": true }, "gene": "CYP2C9", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "2", + "lookupKey": [ + "2" + ], "label": "*1/*1" } ], @@ -1779,7 +2019,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1792,7 +2033,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1805,7 +2047,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1818,7 +2061,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1831,7 +2075,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1844,7 +2089,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1857,7 +2103,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1870,7 +2117,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1883,7 +2131,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1896,7 +2145,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1909,7 +2159,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1922,7 +2173,8 @@ ], "phased": true, "wildtypeAllele": "CAATGGAAAGA", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1935,7 +2187,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1948,7 +2201,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1961,7 +2215,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1974,7 +2229,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -1988,7 +2244,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2002,7 +2259,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2015,7 +2273,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2028,7 +2287,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2043,7 +2303,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2056,7 +2317,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2069,7 +2331,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2083,7 +2346,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2096,7 +2360,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2109,7 +2374,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2122,7 +2388,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2135,7 +2402,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2148,7 +2416,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2161,7 +2430,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2174,7 +2444,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2187,7 +2458,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2200,7 +2472,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2214,7 +2487,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2227,7 +2501,8 @@ ], "phased": true, "wildtypeAllele": "GA", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2240,7 +2515,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2253,7 +2529,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2266,7 +2543,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2279,7 +2557,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2292,7 +2571,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2305,7 +2585,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2318,7 +2599,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2331,7 +2613,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2344,7 +2627,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2357,7 +2641,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2370,7 +2655,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2383,7 +2669,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2396,7 +2683,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2411,7 +2699,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2424,7 +2713,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2437,7 +2727,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2450,7 +2741,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2463,7 +2755,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2476,7 +2769,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2489,7 +2783,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2502,7 +2797,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2515,7 +2811,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2528,7 +2825,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2541,7 +2839,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2554,7 +2853,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2567,7 +2867,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2580,7 +2881,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2593,7 +2895,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2606,7 +2909,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2620,7 +2924,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2633,7 +2938,78 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] + }, + { + "gene": "CYP2C9", + "chromosome": "chr10", + "position": 94938719, + "dbSnpId": null, + "call": null, + "alleles": [ + "*80" + ], + "phased": false, + "wildtypeAllele": "T", + "mismatch": false, + "warnings": [] + }, + { + "gene": "CYP2C9", + "chromosome": "chr10", + "position": 94938788, + "dbSnpId": null, + "call": null, + "alleles": [ + "*83" + ], + "phased": false, + "wildtypeAllele": "C", + "mismatch": false, + "warnings": [] + }, + { + "gene": "CYP2C9", + "chromosome": "chr10", + "position": 94938800, + "dbSnpId": "rs1364419386", + "call": null, + "alleles": [ + "*76" + ], + "phased": false, + "wildtypeAllele": "G", + "mismatch": false, + "warnings": [] + }, + { + "gene": "CYP2C9", + "chromosome": "chr10", + "position": 94941975, + "dbSnpId": null, + "call": null, + "alleles": [ + "*77" + ], + "phased": false, + "wildtypeAllele": "G", + "mismatch": false, + "warnings": [] + }, + { + "gene": "CYP2C9", + "chromosome": "chr10", + "position": 94942243, + "dbSnpId": "rs1375956433", + "call": null, + "alleles": [ + "*78" + ], + "phased": false, + "wildtypeAllele": "T", + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2646,7 +3022,8 @@ ], "phased": false, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2659,7 +3036,8 @@ ], "phased": false, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2672,7 +3050,64 @@ ], "phased": false, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] + }, + { + "gene": "CYP2C9", + "chromosome": "chr10", + "position": 94949145, + "dbSnpId": "rs772782449", + "call": null, + "alleles": [ + "*82" + ], + "phased": false, + "wildtypeAllele": "C", + "mismatch": false, + "warnings": [] + }, + { + "gene": "CYP2C9", + "chromosome": "chr10", + "position": 94949161, + "dbSnpId": null, + "call": null, + "alleles": [ + "*85" + ], + "phased": false, + "wildtypeAllele": "AT", + "mismatch": false, + "warnings": [] + }, + { + "gene": "CYP2C9", + "chromosome": "chr10", + "position": 94972183, + "dbSnpId": null, + "call": null, + "alleles": [ + "*81" + ], + "phased": false, + "wildtypeAllele": "A", + "mismatch": false, + "warnings": [] + }, + { + "gene": "CYP2C9", + "chromosome": "chr10", + "position": 94981258, + "dbSnpId": "rs1297714792", + "call": null, + "alleles": [ + "*79" + ], + "phased": false, + "wildtypeAllele": "C", + "mismatch": false, + "warnings": [] }, { "gene": "CYP2C9", @@ -2685,7 +3120,22 @@ ], "phased": false, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] + }, + { + "gene": "CYP2C9", + "chromosome": "chr10", + "position": 94986174, + "dbSnpId": "rs1441296358", + "call": null, + "alleles": [ + "*84" + ], + "phased": false, + "wildtypeAllele": "G", + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [ @@ -2698,7 +3148,8 @@ "alleles": [], "phased": true, "wildtypeAllele": null, - "mismatch": false + "mismatch": false, + "warnings": [] } ], "highlightedVariants": [] @@ -2709,45 +3160,9 @@ "phased": false, "callSource": "OUTSIDE", "uncalledHaplotypes": [], - "messages": [ - { - "rule_name": "CYP2D6 warning", - "version": "1", - "matches": { - "gene": "CYP2D6", - "hapsCalled": [], - "hapsMissing": [], - "variantsMissing": [], - "variant": "", - "dips": [], - "drugs": [] - }, - "exception_type": "note", - "message": "CYP2D6 genotypes are called by a separate algorithm from other genes in the PharmCAT report. Please refer to \u003ca href\u003d\"https://github.com/PharmGKB/PharmCAT/wiki/Determining-Alleles\"\u003ethe PharmCAT wiki\u003c/a\u003e for more information." - } - ], + "messages": [], "relatedDrugs": [], - "matcherDiplotypes": [ - { - "allele1": { - "gene": "CYP2D6", - "name": "*1", - "function": "Normal function", - "reference": true - }, - "allele2": { - "gene": "CYP2D6", - "name": "*3", - "function": "No function", - "reference": false - }, - "gene": "CYP2D6", - "phenotype": "Intermediate Metabolizer", - "variant": null, - "lookupKey": "1", - "label": "*1/*3" - } - ], + "matcherDiplotypes": [], "diplotypes": [ { "allele1": { @@ -2763,9 +3178,13 @@ "reference": false }, "gene": "CYP2D6", - "phenotype": "Intermediate Metabolizer", + "phenotypes": [ + "Intermediate Metabolizer" + ], "variant": null, - "lookupKey": "1", + "lookupKey": [ + "1" + ], "label": "*1/*3" } ], @@ -2812,9 +3231,13 @@ "reference": true }, "gene": "CYP3A5", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*1/*1" } ], @@ -2833,9 +3256,13 @@ "reference": true }, "gene": "CYP3A5", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*1/*1" } ], @@ -2843,20 +3270,6 @@ { "gene": "CYP3A5", "chromosome": "chr7", - "position": 99652613, - "dbSnpId": "rs28365083", - "call": "G|G", - "alleles": [ - "*2", - "*3" - ], - "phased": true, - "wildtypeAllele": "G", - "mismatch": false - }, - { - "gene": "CYP3A5", - "chromosome": "chr7", "position": 99652770, "dbSnpId": "rs41303343", "call": "T|T", @@ -2865,7 +3278,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP3A5", @@ -2874,12 +3288,12 @@ "dbSnpId": "rs28383479", "call": "C|C", "alleles": [ - "*3", "*9" ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP3A5", @@ -2892,35 +3306,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false - }, - { - "gene": "CYP3A5", - "chromosome": "chr7", - "position": 99665237, - "dbSnpId": "rs56411402", - "call": "T|T", - "alleles": [ - "*3", - "*4" - ], - "phased": true, - "wildtypeAllele": "T", - "mismatch": false - }, - { - "gene": "CYP3A5", - "chromosome": "chr7", - "position": 99666950, - "dbSnpId": "rs55965422", - "call": "A|A", - "alleles": [ - "*3", - "*5" - ], - "phased": true, - "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP3A5", @@ -2933,7 +3320,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP3A5", @@ -2946,7 +3334,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -2975,9 +3364,9 @@ "reference": true }, "gene": "CYP4F2", - "phenotype": null, + "phenotypes": [], "variant": null, - "lookupKey": null, + "lookupKey": [], "label": "*1/*1" } ], @@ -2996,9 +3385,9 @@ "reference": true }, "gene": "CYP4F2", - "phenotype": null, + "phenotypes": [], "variant": null, - "lookupKey": null, + "lookupKey": [], "label": "*1/*1" } ], @@ -3014,7 +3403,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "CYP4F2", @@ -3027,7 +3417,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -3072,9 +3463,13 @@ "reference": true }, "gene": "DPYD", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "2", + "lookupKey": [ + "2" + ], "label": "Reference/Reference" } ], @@ -3093,9 +3488,13 @@ "reference": true }, "gene": "DPYD", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "2", + "lookupKey": [ + "2" + ], "label": "Reference/Reference" } ], @@ -3111,7 +3510,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3124,7 +3524,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3137,7 +3538,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3150,7 +3552,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3163,7 +3566,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3176,7 +3580,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3189,7 +3594,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3202,7 +3608,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3215,7 +3622,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3228,7 +3636,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3241,7 +3650,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3254,7 +3664,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3267,7 +3678,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3280,7 +3692,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3293,7 +3706,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3306,7 +3720,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3319,7 +3734,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3332,7 +3748,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3345,7 +3762,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3358,7 +3776,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3371,7 +3790,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3384,7 +3804,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3397,7 +3818,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3410,7 +3832,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3423,7 +3846,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3436,7 +3860,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3449,7 +3874,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3462,7 +3888,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3475,7 +3902,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3488,7 +3916,8 @@ ], "phased": true, "wildtypeAllele": "TG", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3501,7 +3930,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3514,7 +3944,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3527,7 +3958,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3540,7 +3972,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3553,7 +3986,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3566,7 +4000,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3579,7 +4014,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3592,7 +4028,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3605,7 +4042,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3618,7 +4056,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3631,7 +4070,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3644,7 +4084,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3657,7 +4098,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3670,7 +4112,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3683,7 +4126,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3696,7 +4140,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3709,7 +4154,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3722,7 +4168,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3735,7 +4182,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3748,7 +4196,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3761,7 +4210,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3774,7 +4224,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3787,7 +4238,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3800,7 +4252,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3813,7 +4266,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3826,7 +4280,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3839,7 +4294,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3852,7 +4308,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3865,7 +4322,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3878,7 +4336,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3891,7 +4350,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3904,7 +4364,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3917,7 +4378,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3930,7 +4392,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3943,7 +4406,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3956,7 +4420,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3969,7 +4434,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3982,7 +4448,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -3995,7 +4462,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4008,7 +4476,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4021,7 +4490,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4034,7 +4504,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4047,7 +4518,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4060,7 +4532,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4073,7 +4546,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4086,7 +4560,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4099,7 +4574,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4112,7 +4588,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4125,7 +4602,8 @@ ], "phased": true, "wildtypeAllele": "GATGA", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4138,7 +4616,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4151,7 +4630,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4164,7 +4644,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "DPYD", @@ -4177,7 +4658,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -4191,27 +4673,7 @@ "uncalledHaplotypes": [], "messages": [], "relatedDrugs": [], - "matcherDiplotypes": [ - { - "allele1": { - "gene": "G6PD", - "name": "B (wildtype)", - "function": "Normal function", - "reference": true - }, - "allele2": { - "gene": "G6PD", - "name": "B (wildtype)", - "function": "Normal function", - "reference": true - }, - "gene": "G6PD", - "phenotype": "Normal", - "variant": null, - "lookupKey": "Normal", - "label": "B (wildtype)/B (wildtype)" - } - ], + "matcherDiplotypes": [], "diplotypes": [ { "allele1": { @@ -4227,9 +4689,13 @@ "reference": true }, "gene": "G6PD", - "phenotype": "Normal", + "phenotypes": [ + "Normal" + ], "variant": null, - "lookupKey": "Normal", + "lookupKey": [ + "Normal" + ], "label": "B (wildtype)/B (wildtype)" } ], @@ -4276,9 +4742,9 @@ "reference": true }, "gene": "IFNL3", - "phenotype": null, + "phenotypes": [], "variant": null, - "lookupKey": null, + "lookupKey": [], "label": "rs12979860 reference (C)/rs12979860 reference (C)" } ], @@ -4297,9 +4763,9 @@ "reference": true }, "gene": "IFNL3", - "phenotype": null, + "phenotypes": [], "variant": null, - "lookupKey": null, + "lookupKey": [], "label": "rs12979860 reference (C)/rs12979860 reference (C)" } ], @@ -4315,7 +4781,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -4329,22 +4796,7 @@ "uncalledHaplotypes": [], "messages": [], "relatedDrugs": [], - "matcherDiplotypes": [ - { - "allele1": { - "gene": "MT-RNR1", - "name": "1555A\u003eG", - "function": "increased risk of aminoglycoside-induced hearing loss", - "reference": false - }, - "allele2": null, - "gene": "MT-RNR1", - "phenotype": "increased risk of aminoglycoside-induced hearing loss", - "variant": null, - "lookupKey": "increased risk of aminoglycoside-induced hearing loss", - "label": "1555A\u003eG" - } - ], + "matcherDiplotypes": [], "diplotypes": [ { "allele1": { @@ -4355,9 +4807,13 @@ }, "allele2": null, "gene": "MT-RNR1", - "phenotype": "increased risk of aminoglycoside-induced hearing loss", + "phenotypes": [ + "increased risk of aminoglycoside-induced hearing loss" + ], "variant": null, - "lookupKey": "increased risk of aminoglycoside-induced hearing loss", + "lookupKey": [ + "increased risk of aminoglycoside-induced hearing loss" + ], "label": "1555A\u003eG" } ], @@ -4388,9 +4844,13 @@ "reference": true }, "gene": "NUDT15", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*1/*1" } ], @@ -4409,9 +4869,13 @@ "reference": true }, "gene": "NUDT15", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*1/*1" } ], @@ -4427,7 +4891,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4440,7 +4905,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4455,7 +4921,8 @@ ], "phased": true, "wildtypeAllele": "AGGAGTC", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4468,7 +4935,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4481,7 +4949,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4494,7 +4963,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4507,7 +4977,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4520,7 +4991,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4533,7 +5005,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4546,7 +5019,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4559,7 +5033,8 @@ ], "phased": true, "wildtypeAllele": "GA", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4572,7 +5047,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4585,7 +5061,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4598,7 +5075,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4612,7 +5090,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4625,7 +5104,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "NUDT15", @@ -4638,7 +5118,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -4667,9 +5148,13 @@ "reference": true }, "gene": "RYR1", - "phenotype": "Uncertain Susceptibility", + "phenotypes": [ + "Uncertain Susceptibility" + ], "variant": null, - "lookupKey": "Uncertain Susceptibility", + "lookupKey": [ + "Uncertain Susceptibility" + ], "label": "Reference/Reference" } ], @@ -4688,9 +5173,13 @@ "reference": true }, "gene": "RYR1", - "phenotype": "Uncertain Susceptibility", + "phenotypes": [ + "Uncertain Susceptibility" + ], "variant": null, - "lookupKey": "Uncertain Susceptibility", + "lookupKey": [ + "Uncertain Susceptibility" + ], "label": "Reference/Reference" } ], @@ -4706,7 +5195,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4719,7 +5209,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4732,7 +5223,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4745,7 +5237,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4759,7 +5252,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4772,7 +5266,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4786,7 +5281,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4799,7 +5295,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4812,7 +5309,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4825,7 +5323,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4838,7 +5337,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4851,7 +5351,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4864,7 +5365,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4877,7 +5379,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4890,7 +5393,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4903,7 +5407,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4916,7 +5421,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4929,7 +5435,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4942,7 +5449,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4956,7 +5464,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4969,7 +5478,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4982,7 +5492,8 @@ ], "phased": true, "wildtypeAllele": "TGGA", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -4995,7 +5506,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5008,7 +5520,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5021,7 +5534,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5034,7 +5548,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5047,7 +5562,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5060,7 +5576,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5073,7 +5590,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5086,7 +5604,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5099,7 +5618,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5112,7 +5632,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5125,7 +5646,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5139,7 +5661,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5152,7 +5675,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5165,7 +5689,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5178,7 +5703,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5191,7 +5717,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5204,7 +5731,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5217,7 +5745,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5230,7 +5759,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5243,7 +5773,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5256,7 +5787,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "RYR1", @@ -5269,7 +5801,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -5302,9 +5835,13 @@ "reference": true }, "gene": "SLCO1B1", - "phenotype": "Normal function", + "phenotypes": [ + "Normal Function" + ], "variant": null, - "lookupKey": "Normal function", + "lookupKey": [ + "Normal Function" + ], "label": "*1/*1" } ], @@ -5323,9 +5860,13 @@ "reference": true }, "gene": "SLCO1B1", - "phenotype": "Normal function", + "phenotypes": [ + "Normal Function" + ], "variant": null, - "lookupKey": "Normal function", + "lookupKey": [ + "Normal Function" + ], "label": "*1/*1" } ], @@ -5341,7 +5882,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5354,7 +5896,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5368,7 +5911,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5382,7 +5926,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5413,7 +5958,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5426,7 +5972,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5443,7 +5990,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5457,7 +6005,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5474,7 +6023,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5487,7 +6037,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5506,7 +6057,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5521,7 +6073,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5534,7 +6087,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5547,7 +6101,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5560,7 +6115,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5573,7 +6129,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5586,7 +6143,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5599,7 +6157,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5613,7 +6172,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5628,7 +6188,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5642,7 +6203,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5656,7 +6218,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5669,7 +6232,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5682,7 +6246,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5695,7 +6260,8 @@ ], "phased": false, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5708,7 +6274,8 @@ ], "phased": false, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5721,7 +6288,8 @@ ], "phased": false, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5734,7 +6302,8 @@ ], "phased": false, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5747,7 +6316,8 @@ ], "phased": false, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5761,7 +6331,8 @@ ], "phased": false, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "SLCO1B1", @@ -5775,7 +6346,8 @@ ], "phased": false, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -5822,9 +6394,13 @@ "reference": true }, "gene": "TPMT", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*1/*1" } ], @@ -5843,9 +6419,13 @@ "reference": true }, "gene": "TPMT", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*1/*1" } ], @@ -5863,7 +6443,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -5876,7 +6457,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -5889,7 +6471,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -5902,7 +6485,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -5915,7 +6499,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -5928,7 +6513,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -5941,7 +6527,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -5954,7 +6541,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -5967,7 +6555,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -5980,7 +6569,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -5993,7 +6583,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6006,7 +6597,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6019,7 +6611,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6032,7 +6625,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6045,7 +6639,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6058,7 +6653,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6071,7 +6667,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6085,7 +6682,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6098,7 +6696,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6112,7 +6711,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6125,7 +6725,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6138,7 +6739,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6151,7 +6753,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6164,7 +6767,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6177,7 +6781,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6190,7 +6795,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6203,7 +6809,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6216,7 +6823,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6229,7 +6837,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6242,7 +6851,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6255,7 +6865,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6268,7 +6879,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6281,7 +6893,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6294,7 +6907,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6307,7 +6921,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6320,7 +6935,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6333,7 +6949,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6346,7 +6963,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6359,7 +6977,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6372,7 +6991,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6385,7 +7005,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6398,7 +7019,8 @@ ], "phased": true, "wildtypeAllele": "A", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "TPMT", @@ -6411,7 +7033,8 @@ ], "phased": true, "wildtypeAllele": "T", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -6456,9 +7079,13 @@ "reference": true }, "gene": "UGT1A1", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*1/*1" } ], @@ -6477,9 +7104,13 @@ "reference": true }, "gene": "UGT1A1", - "phenotype": "Normal Metabolizer", + "phenotypes": [ + "Normal Metabolizer" + ], "variant": null, - "lookupKey": "Normal Metabolizer", + "lookupKey": [ + "Normal Metabolizer" + ], "label": "*1/*1" } ], @@ -6497,7 +7128,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "UGT1A1", @@ -6514,7 +7146,8 @@ ], "phased": true, "wildtypeAllele": "CAT", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "UGT1A1", @@ -6527,7 +7160,8 @@ ], "phased": true, "wildtypeAllele": "G", - "mismatch": false + "mismatch": false, + "warnings": [] }, { "gene": "UGT1A1", @@ -6540,7 +7174,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [], @@ -6600,9 +7235,9 @@ "reference": true }, "gene": "VKORC1", - "phenotype": null, + "phenotypes": [], "variant": null, - "lookupKey": null, + "lookupKey": [], "label": "rs9923231 reference (C)/rs9923231 reference (C)" } ], @@ -6621,9 +7256,9 @@ "reference": true }, "gene": "VKORC1", - "phenotype": null, + "phenotypes": [], "variant": null, - "lookupKey": null, + "lookupKey": [], "label": "rs9923231 reference (C)/rs9923231 reference (C)" } ], @@ -6639,7 +7274,8 @@ ], "phased": true, "wildtypeAllele": "C", - "mismatch": false + "mismatch": false, + "warnings": [] } ], "variantsOfInterest": [],