Mercurial > repos > bioit_sciensano > phagetermvirome
comparison _modules/utilities.py @ 0:69e8f12c8b31 draft
"planemo upload"
author | bioit_sciensano |
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date | Fri, 11 Mar 2022 15:06:20 +0000 |
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-1:000000000000 | 0:69e8f12c8b31 |
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1 ## @file utilities.py | |
2 # | |
3 # Gather here utility methods for phageterm. Used in both CPU and GPU version. | |
4 #from string import maketrans | |
5 import re | |
6 import random | |
7 import sys | |
8 | |
9 import numpy as np | |
10 import datetime | |
11 | |
12 if sys.version_info < (3,): | |
13 import string | |
14 TRANSTAB = string.maketrans("ACGTN", "TGCAN") | |
15 else: | |
16 TRANSTAB = str.maketrans("ACGTN", "TGCAN") | |
17 | |
18 def checkReportTitle(report_title): | |
19 """Normalise report title (take out any special char)""" | |
20 default_title="Analysis_" | |
21 right_now=datetime.datetime.now() | |
22 default_title+=str(right_now.month) | |
23 default_title+=str(right_now.day) | |
24 default_title+="_" | |
25 default_title+=str(right_now.hour) | |
26 default_title+=str(right_now.minute) | |
27 titleNorm = "" | |
28 charok = list(range(48,58)) + list(range(65,91)) + list(range(97,123)) + [45,95] | |
29 for char in report_title: | |
30 if ord(char) in charok: | |
31 titleNorm += char | |
32 if len(titleNorm) > 1: | |
33 return titleNorm[:20] | |
34 else: | |
35 return default | |
36 | |
37 ### SEQUENCE manipulation function | |
38 def changeCase(seq): | |
39 """Change lower case to UPPER CASE for a sequence string.""" | |
40 return seq.upper() | |
41 | |
42 | |
43 def reverseComplement(seq, transtab=str.maketrans('ATGCN', 'TACGN')): | |
44 """Reverse Complement a sequence.""" | |
45 return changeCase(seq).translate(transtab)[::-1] | |
46 | |
47 def longest_common_substring(read, refseq): | |
48 """Longest common substring between two strings.""" | |
49 m = [[0] * (1 + len(refseq)) for i in range(1 + len(read))] | |
50 longest, x_longest = 0, 0 | |
51 for x in range(1, 1 + len(read)): | |
52 for y in range(1, 1 + len(refseq)): | |
53 if read[x - 1] == refseq[y - 1]: | |
54 m[x][y] = m[x - 1][y - 1] + 1 | |
55 if m[x][y] > longest: | |
56 longest = m[x][y] | |
57 x_longest = x | |
58 else: | |
59 m[x][y] = 0 | |
60 return read[x_longest - longest: x_longest] | |
61 | |
62 def hybridCoverage(read, sequence, hybrid_coverage, start, end): | |
63 """Return hybrid coverage.""" | |
64 aligned_part_only = longest_common_substring(read, sequence[start:end]) | |
65 for i in range(start, min(len(sequence),start+len(aligned_part_only))): | |
66 hybrid_coverage[i]+=1 | |
67 return hybrid_coverage | |
68 | |
69 ## Determines if readPart maps against Sequence. | |
70 # | |
71 # @param readPart A part of a read (seed characters usually) | |
72 # @param sequence (a contig) | |
73 # It choses randomly a mapping position amongst all mappings found. | |
74 # It returns 2 numbers: the start and stop position of the chosen mapping location. | |
75 def applyCoverage(readPart, sequence): | |
76 """Return a random match of a read onto the sequence. """ | |
77 position = [] | |
78 for pos in re.finditer(readPart,sequence): | |
79 position.append(pos) | |
80 if len(position) > 0: | |
81 match = random.choice(position) | |
82 return match.start(), match.end() | |
83 else: | |
84 return -1, -1 | |
85 | |
86 def correctEdge(coverage, edge): | |
87 """Correction of the Edge coverage. """ | |
88 correctCov = np.array([len(coverage[0])*[0], len(coverage[0])*[0]]) | |
89 End = len(coverage[0]) | |
90 covSta = range(edge) | |
91 covEnd = range(End-edge,End) | |
92 for i in range(len(coverage)): | |
93 for j in range(len(coverage[i])): | |
94 correctCov[i][j] = coverage[i][j] | |
95 for k in covSta: | |
96 correctCov[i][k+edge] += coverage[i][k+End-edge] | |
97 for l in covEnd: | |
98 correctCov[i][l-edge] += coverage[i][l-End+edge] | |
99 return correctCov | |
100 | |
101 # utility class for storing results of decisionProcess function | |
102 class DecisionProcessOutput: | |
103 def __init__(self, Redundant, Permuted, P_class, P_type, P_seqcoh, P_concat, | |
104 P_orient, P_left, P_right, Mu_like): | |
105 pass | |
106 |