Mercurial > repos > computationaltranscriptomics > vgx_converter
diff test-data/angiogenesis_network.sif @ 2:f5e05d6382c8 draft
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| author | computationaltranscriptomics |
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| date | Tue, 23 Feb 2016 09:17:36 -0500 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/angiogenesis_network.sif Tue Feb 23 09:17:36 2016 -0500 @@ -0,0 +1,322 @@ +p(HGNC:FGF9) isA p(PFH:"FGF Family") +p(HGNC:FGF10) isA p(PFH:"FGF Family") +p(HGNC:FGF18) isA p(PFH:"FGF Family") +p(HGNC:FGF1) isA p(PFH:"FGF Family") +p(HGNC:FGF2) isA p(PFH:"FGF Family") +p(HGNC:FGF16) isA p(PFH:"FGF Family") +p(HGNC:FGF5) isA p(PFH:"FGF Family") +p(HGNC:FGF7) isA p(PFH:"FGF Family") +p(HGNC:FGF8) isA p(PFH:"FGF Family") +p(PFH:"FGF Family") increases kin(p(PFH:"FGFR Family")) +p(HGNC:KNG1) directlyIncreases cat(p(HGNC:BDKRB1)) +p(HGNC:KNG1) directlyIncreases cat(p(HGNC:BDKRB2)) +p(HGNC:SIRT1) actsIn cat(p(HGNC:SIRT1)) +p(HGNC:CXCL12) directlyIncreases cat(p(HGNC:CXCR4)) +p(HGNC:NRP1) actsIn cat(p(HGNC:NRP1)) +p(HGNC:NRP1) increases kin(p(HGNC:FLT1)) +cat(p(HGNC:NRP1)) directlyIncreases kin(p(HGNC:KDR)) +p(HGNC:JAG1) directlyIncreases tscript(p(PFH:"NOTCH Family")) +p(HGNC:TGFB1) isA p(PFH:"TGFB Family") +p(HGNC:TGFB2) isA p(PFH:"TGFB Family") +p(PFH:"TGFB Family") directlyIncreases kin(p(HGNC:TGFBR2)) +p(HGNC:PDGFRB) isA p(PFH:"PDGFR Family") +p(PFH:"PDGFR Family") actsIn kin(p(PFH:"PDGFR Family")) +p(HGNC:PDGFRA) isA p(PFH:"PDGFR Family") +p(HGNC:PDGFRB) actsIn kin(p(HGNC:PDGFRB)) +p(HGNC:COL18A1) decreases kin(p(PFH:"MAPK p38 Family")) +p(HGNC:COL18A1) decreases kin(p(HGNC:MAPK3)) +p(HGNC:COL18A1) decreases kin(p(HGNC:KDR)) +p(HGNC:COL18A1) decreases kin(p(HGNC:PTK2)) +p(HGNC:COL18A1) decreases kin(p(HGNC:MAPK1)) +p(HGNC:BCL6B) actsIn cat(p(MGI:Bcl6b)) +cat(p(MGI:Bcl6b)) increases deg(p(MGI:Rbpj)) +p(HGNC:EGLN2) actsIn cat(p(HGNC:EGLN2)) +cat(p(HGNC:EGLN2)) increases deg(p(HGNC:HIF1A)) +p(HGNC:PRKAA1) actsIn kin(p(HGNC:PRKAA1)) +kin(p(HGNC:PRKAA1)) increases bp(GO:"blood vessel development") +p(HGNC:UNC5B) actsIn cat(p(HGNC:UNC5B)) +cat(p(HGNC:UNC5B)) decreases bp(GO:"patterning of blood vessels") +complex(p(HGNC:PDGFA),p(HGNC:PDGFB)) hasComponent p(HGNC:PDGFA) +complex(p(HGNC:PDGFA),p(HGNC:PDGFB)) hasComponent p(HGNC:PDGFB) +p(HGNC:TIE1) actsIn kin(p(HGNC:TIE1)) +kin(p(HGNC:EGFR)) increases kin(p(HGNC:MAPK3)) +kin(p(HGNC:EGFR)) increases kin(p(HGNC:MAPK1)) +p(HGNC:TGFA) directlyIncreases kin(p(HGNC:EGFR)) +deg(p(MGI:Rbpj)) directlyDecreases p(HGNC:RBPJ) +a(CHEBI:"angiotensin II") increases p(HGNC:VEGFA) +a(CHEBI:"angiotensin II") directlyIncreases cat(p(HGNC:AGTR1)) +a(CHEBI:"angiotensin II") increases tscript(p(HGNC:HIF1A)) +a(CHEBI:"angiotensin II") increases p(HGNC:HIF1A) +p(HGNC:SHH) increases gtp(p(HGNC:RHOA)) +p(HGNC:NOS3) increases bp(GO:angiogenesis) +p(HGNC:NOS3) actsIn cat(p(HGNC:NOS3)) +p(HGNC:ANGPT2) directlyDecreases kin(p(HGNC:TEK)) +p(HGNC:ANGPT2) decreases p(HGNC:ANGPT1) +p(HGNC:ANGPT2) directlyDecreases kin(p(HGNC:TIE1)) +p(HGNC:ROBO4) actsIn cat(p(MGI:Robo4)) +p(HGNC:OLR1) increases bp(GO:"patterning of blood vessels") +cat(p(HGNC:AGTR1)) increases p(HGNC:OLR1) +p(HGNC:KLF2) decreases p(HGNC:HIF1A) +p(HGNC:KLF2) actsIn tscript(p(HGNC:KLF2)) +kin(p(HGNC:PDGFRB)) increases kin(p(HGNC:MAPK3)) +kin(p(HGNC:PDGFRB)) increases kin(p(HGNC:SRC)) +kin(p(HGNC:PDGFRB)) increases kin(p(HGNC:MAPK1)) +p(HGNC:EPAS1) actsIn tscript(p(HGNC:EPAS1)) +p(HGNC:BDKRB1) actsIn cat(p(HGNC:BDKRB1)) +gtp(p(HGNC:RHOA)) directlyIncreases kin(p(HGNC:ROCK1)) +complex(p(HGNC:ECT2),p(HGNC:KLHL20)) hasComponent p(HGNC:ECT2) +complex(p(HGNC:ECT2),p(HGNC:KLHL20)) increases gtp(p(HGNC:RHOA)) +complex(p(HGNC:ECT2),p(HGNC:KLHL20)) hasComponent p(HGNC:KLHL20) +p(HGNC:ECT2) increases bp(GO:"patterning of blood vessels") +p(HGNC:MMP2) actsIn cat(p(HGNC:MMP2)) +cat(p(HGNC:MMP2)) increases p(HGNC:VEGFA) +p(HGNC:RAF1) actsIn kin(p(HGNC:RAF1)) +kin(p(HGNC:RAF1)) increases kin(p(HGNC:ROCK2)) +p(HGNC:ENG) increases kin(p(HGNC:ACVRL1)) +p(HGNC:ENG) decreases kin(p(HGNC:TGFBR1)) +a(CHEBI:"sphingosine 1-phosphate") increases bp(GO:"patterning of blood vessels") +p(HGNC:FGFR1) actsIn kin(p(HGNC:FGFR1)) +p(HGNC:FGFR2) isA p(PFH:"FGFR Family") +p(HGNC:FGFR3) isA p(PFH:"FGFR Family") +p(HGNC:FGFR1) isA p(PFH:"FGFR Family") +p(PFH:"FGFR Family") actsIn kin(p(PFH:"FGFR Family")) +p(HGNC:FGFR4) isA p(PFH:"FGFR Family") +p(HGNC:FGFR2) actsIn kin(p(HGNC:FGFR2)) +p(HGNC:MAPK3) actsIn kin(p(HGNC:MAPK3)) +p(HGNC:EP300) directlyIncreases tscript(p(HGNC:EPAS1)) +p(HGNC:EP300) actsIn tscript(p(HGNC:EP300)) +complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1)) hasComponent p(HGNC:TCEB2) +complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1)) hasComponent p(HGNC:CUL2) +complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1)) hasComponent p(HGNC:TCEB1) +complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1)) increases deg(p(HGNC:HIF1A)) +complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1)) hasComponent p(HGNC:VHL) +complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1)) hasComponent p(HGNC:RBX1) +p(HGNC:EFNB2) decreases bp(GO:"patterning of blood vessels") +p(HGNC:EFNB2) directlyIncreases kin(p(HGNC:EPHB4)) +p(HGNC:PXN) increases bp(GO:"cell migration") +kin(p(HGNC:PTK2)) increases bp(GO:"cell migration") +p(HGNC:HEY1) decreases bp(GO:"patterning of blood vessels") +p(HGNC:SMAD4) increases p(HGNC:HEY2) +p(HGNC:SMAD4) increases p(HGNC:HEY1) +p(HGNC:SMAD4) increases bp(GO:"cell migration") +p(HGNC:SMAD4) actsIn tscript(p(HGNC:SMAD4)) +p(HGNC:PLXND1) actsIn cat(p(MGI:Plxnd1)) +p(HGNC:SMAD2) actsIn tscript(p(HGNC:SMAD2)) +kin(p(PFH:"FGFR Family")) increases kin(p(PFH:?PIK3C Class IA Family?)) +kin(p(PFH:"FGFR Family")) increases cat(p(HGNC:PLCG1)) +kin(p(PFH:"FGFR Family")) increases kin(p(PFH:"MAPK p38 Family")) +tscript(p(HGNC:SMAD2)) decreases bp(GO:"cell migration") +tscript(p(HGNC:SMAD2)) decreases bp(GO:"cell proliferation") +p(HGNC:VTN) directlyIncreases cat(complex(p(HGNC:ITGAV),p(HGNC:ITGB3))) +tscript(p(HGNC:FOXO1)) decreases bp(GO:angiogenesis) +tscript(p(HGNC:FOXO1)) directlyDecreases p(HGNC:NOS3) +tscript(p(HGNC:FOXO1)) decreases bp(GO:"cell migration") +tscript(p(HGNC:FOXO1)) increases p(HGNC:ANGPT2) +p(HGNC:FOXO1) actsIn tscript(p(HGNC:FOXO1)) +complex(p(HGNC:PDGFA),p(HGNC:PDGFA)) isA p(PFH:"PDGF Family") +complex(p(HGNC:PDGFC),p(HGNC:PDGFC)) isA p(PFH:"PDGF Family") +complex(p(HGNC:PDGFB),p(HGNC:PDGFB)) isA p(PFH:"PDGF Family") +p(PFH:"PDGF Family") increases kin(p(PFH:"PDGFR Family")) +complex(p(HGNC:PDGFA),p(HGNC:PDGFA)) hasComponent p(HGNC:PDGFA) +p(HGNC:NIN) increases bp(GO:"blood vessel development") +kin(p(HGNC:MAPK3)) increases p(HGNC:PXN) +kin(p(HGNC:MAPK3)) increases bp(GO:"cell proliferation") +p(HGNC:FGFR3) actsIn kin(p(HGNC:FGFR3)) +p(HGNC:EDN1) increases tscript(p(HGNC:HIF1A)) +kin(p(HGNC:TIE1)) decreases bp(MESHPP:Apoptosis) +p(HGNC:ANGPT1) directlyIncreases kin(p(HGNC:TEK)) +p(HGNC:ANGPT1) directlyIncreases kin(p(HGNC:TIE1)) +p(HGNC:EGLN3) actsIn cat(p(HGNC:EGLN3)) +deg(p(HGNC:HIF1A)) directlyDecreases p(HGNC:HIF1A) +cat(p(HGNC:EGLN3)) increases deg(p(HGNC:HIF1A)) +p(HGNC:NCF1) increases bp(GO:"patterning of blood vessels") +cat(p(MGI:Plxnd1)) decreases tscript(p(PFH:"NOTCH Family")) +p(HGNC:SEMA3E) increases cat(p(MGI:Plxnd1)) +tscript(p(HGNC:SMAD1)) increases bp(GO:"cell migration") +tscript(p(HGNC:SMAD1)) increases bp(GO:"cell proliferation") +p(HGNC:SMAD1) actsIn tscript(p(HGNC:SMAD1)) +complex(p(HGNC:ITGA2),p(HGNC:ITGB1)) increases p(HGNC:DLL4) +complex(p(HGNC:ITGA2),p(HGNC:ITGB1)) increases p(HGNC:FOXC2) +complex(p(HGNC:ITGA2),p(HGNC:ITGB1)) hasComponent p(HGNC:ITGA2) +complex(p(HGNC:ITGA2),p(HGNC:ITGB1)) hasComponent p(HGNC:ITGB1) +p(HGNC:IGF1R) actsIn kin(p(HGNC:IGF1R)) +p(HGNC:PLCG1) actsIn cat(p(HGNC:PLCG1)) +bp(GO:angiogenesis) subProcessOf bp(GO:"blood vessel development") +bp(GO:"patterning of blood vessels") isA bp(GO:angiogenesis) +bp(GO:"regulation of vascular permeability") subProcessOf bp(GO:angiogenesis) +cat(p(HGNC:NOS3)) increases bp(GO:angiogenesis) +cat(p(HGNC:NOS3)) increases bp(GO:"regulation of vascular permeability") +cat(p(HGNC:NOS3)) increases bp(GO:"cell migration") +kin(p(HGNC:EPHB4)) decreases bp(GO:"patterning of blood vessels") +p(HGNC:EPHB4) actsIn kin(p(HGNC:EPHB4)) +p(HGNC:HEY2) decreases bp(GO:"patterning of blood vessels") +p(HGNC:KRIT1) increases p(HGNC:DLL4) +kin(p(HGNC:IGF1R)) directlyIncreases kin(p(PFH:?PIK3C Class IA Family?)) +kin(p(HGNC:IGF1R)) increases kin(p(HGNC:SRC)) +kin(p(HGNC:IGF1R)) increases p(HGNC:HIF1A) +p(HGNC:IGF1) increases p(HGNC:HIF1A) +p(HGNC:IGF1) directlyIncreases kin(p(HGNC:IGF1R)) +p(HGNC:TGFBR2) actsIn kin(p(HGNC:TGFBR2)) +kin(p(HGNC:TGFBR2)) increases kin(p(HGNC:ACVRL1)) +kin(p(HGNC:TGFBR2)) directlyIncreases kin(p(HGNC:TGFBR1)) +p(HGNC:LGALS3) increases kin(p(HGNC:KDR)) +p(HGNC:LGALS3) increases complex(p(HGNC:ITGAV),p(HGNC:ITGB3)) +p(HGNC:LGALS3) increases bp(GO:"blood vessel development") +bp(GO:"cell proliferation") subProcessOf bp(GO:angiogenesis) +bp(GO:"cell migration") subProcessOf bp(GO:angiogenesis) +complex(p(HGNC:PDGFC),p(HGNC:PDGFC)) hasComponent p(HGNC:PDGFC) +p(HGNC:FZD4) increases bp(GO:"patterning of blood vessels") +kin(p(HGNC:MET)) increases kin(p(HGNC:MAPK1)) +kin(p(HGNC:MET)) increases kin(p(HGNC:MAPK3)) +p(HGNC:HGF) directlyIncreases kin(p(HGNC:MET)) +p(HGNC:FOXC2) actsIn tscript(p(HGNC:FOXC2)) +kin(p(HGNC:TEK)) decreases bp(MESHPP:Apoptosis) +kin(p(HGNC:TEK)) decreases tscript(p(HGNC:FOXO3)) +kin(p(HGNC:TEK)) increases bp(GO:"cell migration") +kin(p(HGNC:TEK)) decreases tscript(p(HGNC:FOXO1)) +p(HGNC:TEK) actsIn kin(p(HGNC:TEK)) +cat(p(HGNC:SIRT1)) increases bp(GO:angiogenesis) +cat(p(HGNC:SIRT1)) increases bp(GO:"patterning of blood vessels") +r(HGNC:MIR34A) decreases cat(p(HGNC:SIRT1)) +p(HGNC:KDR) actsIn kin(p(HGNC:KDR)) +kin(p(HGNC:PDGFRA)) increases kin(p(HGNC:MAPK1)) +kin(p(HGNC:PDGFRA)) increases kin(p(HGNC:MAPK3)) +p(HGNC:PDGFRA) actsIn kin(p(HGNC:PDGFRA)) +p(HGNC:FGFR4) actsIn kin(p(HGNC:FGFR4)) +complex(p(HGNC:PDGFB),p(HGNC:PDGFB)) hasComponent p(HGNC:PDGFB) +complex(p(HGNC:ITGA6),p(HGNC:ITGB1)) hasComponent p(HGNC:ITGB1) +complex(p(HGNC:ITGA6),p(HGNC:ITGB1)) increases p(HGNC:DLL4) +complex(p(HGNC:ITGA6),p(HGNC:ITGB1)) hasComponent p(HGNC:ITGA6) +tscript(p(HGNC:RBPJ)) directlyIncreases p(HGNC:HEY2) +p(HGNC:RBPJ) actsIn tscript(p(HGNC:RBPJ)) +p(HGNC:RBPJ) directlyIncreases tscript(p(PFH:"NOTCH Family")) +p(HGNC:VEGFB) directlyIncreases kin(p(HGNC:FLT1)) +kin(p(HGNC:KDR)) increases bp(GO:"cell migration") +kin(p(HGNC:KDR)) increases bp(GO:"regulation of vascular permeability") +kin(p(HGNC:KDR)) increases bp(GO:"cell proliferation") +kin(p(HGNC:KDR)) decreases bp(MESHPP:Apoptosis) +p(HGNC:PDGFC) directlyIncreases kin(p(HGNC:KDR)) +p(PFH:"AKT Family") actsIn kin(p(PFH:"AKT Family")) +p(HGNC:CDH5) increases kin(p(PFH:"AKT Family")) +tscript(p(HGNC:CREBBP)) increases tscript(p(HGNC:HIF1A)) +p(HGNC:CREBBP) actsIn tscript(p(HGNC:CREBBP)) +p(HGNC:CREBBP) directlyIncreases tscript(p(HGNC:EPAS1)) +kin(p(PFH:"MAPK p38 Family")) increases bp(GO:"cell migration") +p(PFH:"MAPK p38 Family") actsIn kin(p(PFH:"MAPK p38 Family")) +kin(p(HGNC:MAP2K1)) directlyIncreases kin(p(HGNC:MAPK3)) +kin(p(HGNC:MAP2K1)) directlyIncreases kin(p(HGNC:MAPK1)) +p(HGNC:MAP2K1) actsIn kin(p(HGNC:MAP2K1)) +a(SCHEM:Diacylglycerol) directlyIncreases kin(p(PFH:"PRKC Family")) +p(HGNC:F2) actsIn cat(p(HGNC:F2)) +cat(p(HGNC:F2)) increases bp(GO:"blood vessel development") +p(HGNC:NR2F2) actsIn tscript(p(HGNC:NR2F2)) +tscript(p(HGNC:NR2F2)) decreases tscript(p(PFH:"NOTCH Family")) +kin(p(HGNC:ROCK2)) increases bp(GO:"patterning of blood vessels") +p(HGNC:ROCK2) actsIn kin(p(HGNC:ROCK2)) +p(HGNC:DLL4) increases tscript(p(PFH:"NOTCH Family")) +tscript(p(HGNC:FOXC2)) increases p(HGNC:DLL4) +p(HGNC:VEGFA) increases bp(GO:"regulation of vascular permeability") +p(HGNC:VEGFA) directlyIncreases kin(p(HGNC:FLT1)) +p(HGNC:VEGFA) increases kin(p(PFH:"MAPK p38 Family")) +p(HGNC:VEGFA) directlyIncreases kin(p(HGNC:KDR)) +p(HGNC:VEGFA) increases p(HGNC:NOS3) +a(SCHEM:"kringle 5") decreases p(HGNC:VEGFA) +p(HGNC:GDF2) directlyIncreases kin(p(HGNC:ACVRL1)) +cat(p(HGNC:HIF1AN)) directlyDecreases tscript(p(HGNC:HIF1A)) +p(HGNC:HIF1AN) actsIn cat(p(HGNC:HIF1AN)) +p(HGNC:FLT1) actsIn kin(p(HGNC:FLT1)) +kin(p(HGNC:FLT1)) increases bp(GO:angiogenesis) +p(HGNC:TNXB) increases kin(p(HGNC:FLT1)) +complex(p(HGNC:ETV6),p(HGNC:CTBP1)) hasComponent p(HGNC:CTBP1) +complex(p(HGNC:ETV6),p(HGNC:CTBP1)) increases bp(GO:"patterning of blood vessels") +complex(p(HGNC:ETV6),p(HGNC:CTBP1)) hasComponent p(HGNC:ETV6) +kin(p(HGNC:TGFBR1)) directlyIncreases tscript(p(HGNC:SMAD2)) +kin(p(HGNC:TGFBR1)) directlyIncreases tscript(p(HGNC:SMAD3)) +kin(p(HGNC:TGFBR1)) increases kin(p(PFH:"MAPK p38 Family")) +p(HGNC:TGFBR1) actsIn kin(p(HGNC:TGFBR1)) +p(HGNC:KLHL20) increases bp(GO:"patterning of blood vessels") +p(HGNC:EIF4E) actsIn cat(p(HGNC:EIF4E)) +p(HGNC:HIF1A) actsIn tscript(p(HGNC:HIF1A)) +cat(p(HGNC:EIF4E)) increases p(HGNC:HIF1A) +kin(p(PFH:"AKT Family")) decreases bp(MESHPP:Apoptosis) +kin(p(PFH:"AKT Family")) increases bp(GO:"patterning of blood vessels") +kin(p(PFH:"AKT Family")) increases cat(p(HGNC:NOS3)) +kin(p(PFH:"AKT Family")) increases p(HGNC:PXN) +p(HGNC:ANXA2) increases kin(p(PFH:"AKT Family")) +cat(complex(p(HGNC:ITGAV),p(HGNC:ITGB3))) increases kin(p(HGNC:KDR)) +complex(p(HGNC:ITGAV),p(HGNC:ITGB3)) actsIn cat(complex(p(HGNC:ITGAV),p(HGNC:ITGB3))) +kin(p(PFH:"PRKC Family")) increases bp(GO:"regulation of vascular permeability") +kin(p(PFH:"PRKC Family")) increases kin(p(HGNC:MAPK3)) +kin(p(PFH:"PRKC Family")) increases kin(p(HGNC:MAPK1)) +p(PFH:"PRKC Family") actsIn kin(p(PFH:"PRKC Family")) +cat(p(HGNC:BDKRB2)) DefaultEdge p(HGNC:VEGFA) +p(HGNC:BDKRB2) actsIn cat(p(HGNC:BDKRB2)) +cat(p(HGNC:PLCG1)) increases kin(p(PFH:"PRKC Family")) +kin(p(PFH:"PDGFR Family")) increases kin(p(PFH:?PIK3C Class IA Family?)) +kin(p(PFH:"PDGFR Family")) increases kin(p(HGNC:MAPK1)) +kin(p(PFH:"PDGFR Family")) increases cat(p(HGNC:PLCG1)) +kin(p(HGNC:SRC)) directlyIncreases kin(p(HGNC:PTK2)) +kin(p(HGNC:SRC)) increases cat(p(HGNC:PLCG1)) +kin(p(HGNC:SRC)) increases bp(GO:"regulation of vascular permeability") +p(HGNC:SRC) actsIn kin(p(HGNC:SRC)) +tscript(p(HGNC:PPARA)) decreases kin(p(PFH:"AKT Family")) +p(HGNC:PPARA) actsIn tscript(p(HGNC:PPARA)) +p(HGNC:ITGB1BP1) decreases bp(GO:"patterning of blood vessels") +tscript(p(HGNC:SMAD3)) decreases bp(GO:"cell proliferation") +tscript(p(HGNC:SMAD3)) decreases bp(GO:"cell migration") +p(HGNC:SMAD3) actsIn tscript(p(HGNC:SMAD3)) +tscript(p(HGNC:SMAD5)) increases bp(GO:"cell proliferation") +tscript(p(HGNC:SMAD5)) increases bp(GO:"cell migration") +p(HGNC:SMAD5) actsIn tscript(p(HGNC:SMAD5)) +cat(p(HGNC:CXCR4)) increases bp(GO:"patterning of blood vessels") +p(HGNC:CXCR4) actsIn cat(p(HGNC:CXCR4)) +kin(p(PFH:?PIK3C Class IA Family?)) increases kin(p(PFH:"AKT Family")) +complex(NCH:"p85/p110 PI3Kinase Complex") actsIn kin(p(PFH:?PIK3C Class IA Family?)) +p(PFH:"NOTCH Family") actsIn tscript(p(PFH:"NOTCH Family")) +tscript(p(HGNC:EP300)) directlyIncreases tscript(p(HGNC:HIF1A)) +cat(p(HGNC:SHC1)) increases kin(p(HGNC:MAPK1)) +cat(p(HGNC:SHC1)) increases kin(p(HGNC:MAPK3)) +p(HGNC:SHC1) actsIn cat(p(HGNC:SHC1)) +tscript(p(HGNC:NOTCH4)) increases tscript(p(HGNC:RBPJ)) +tscript(p(HGNC:NOTCH4)) decreases bp(GO:"patterning of blood vessels") +p(HGNC:NOTCH4) actsIn tscript(p(HGNC:NOTCH4)) +p(HGNC:S100A11) increases bp(GO:"patterning of blood vessels") +kin(p(HGNC:ACVRL1)) increases tscript(p(HGNC:SMAD5)) +kin(p(HGNC:ACVRL1)) increases tscript(p(HGNC:SMAD1)) +p(HGNC:ACVRL1) actsIn kin(p(HGNC:ACVRL1)) +kin(p(HGNC:ROCK1)) increases bp(GO:angiogenesis) +p(HGNC:ROCK1) actsIn kin(p(HGNC:ROCK1)) +p(HGNC:RAP1B) increases bp(GO:"patterning of blood vessels") +p(HGNC:ARNT) actsIn tscript(p(HGNC:ARNT)) +tscript(p(HGNC:HIF1A)) increases p(HGNC:TGFA) +tscript(p(HGNC:HIF1A)) increases p(HGNC:VEGFC) +tscript(p(HGNC:HIF1A)) increases p(HGNC:ANGPT2) +tscript(p(HGNC:HIF1A)) increases bp(GO:angiogenesis) +tscript(p(HGNC:HIF1A)) directlyIncreases p(HGNC:VEGFA) +tscript(p(HGNC:HIF1A)) directlyIncreases p(HGNC:PDGFB) +tscript(p(HGNC:HIF1A)) increases p(HGNC:MMP2) +tscript(p(HGNC:HIF1A)) increases p(HGNC:FGF2) +tscript(p(HGNC:HIF1A)) increases p(HGNC:MMP9) +tscript(p(HGNC:HIF1A)) directlyIncreases p(HGNC:PTGS2) +tscript(p(HGNC:HIF1A)) increases p(HGNC:SERPINE1) +tscript(p(HGNC:HIF1A)) increases p(HGNC:ANGPT1) +tscript(p(HGNC:ARNT)) directlyIncreases tscript(p(HGNC:HIF1A)) +tscript(p(HGNC:ARNT)) directlyIncreases tscript(p(HGNC:EPAS1)) +cat(p(HGNC:EGLN1)) increases deg(p(HGNC:HIF1A)) +p(HGNC:EGLN1) actsIn cat(p(HGNC:EGLN1)) +p(HGNC:MMP14) actsIn cat(p(HGNC:MMP14)) +cat(p(HGNC:MMP14)) increases bp(GO:"blood vessel development") +tscript(p(PFH:"NOTCH Family")) increases p(HGNC:HEY2) +tscript(p(PFH:"NOTCH Family")) increases p(HGNC:HEY1) +tscript(p(HGNC:NOTCH4)) isA tscript(p(PFH:"NOTCH Family")) +tscript(p(PFH:"NOTCH Family")) decreases bp(GO:"patterning of blood vessels") +p(HGNC:EGFL7) directlyDecreases tscript(p(PFH:"NOTCH Family")) +cat(p(MGI:Robo4)) decreases bp(GO:"blood vessel development") +p(HGNC:SLIT2) increases cat(p(MGI:Robo4)) +kin(p(HGNC:MAPK1)) increases p(HGNC:PXN) +kin(p(HGNC:MAPK1)) increases bp(GO:"cell proliferation") +p(HGNC:MAPK1) actsIn kin(p(HGNC:MAPK1)) +tscript(p(HGNC:FOXO3)) decreases bp(GO:"cell migration") +tscript(p(HGNC:FOXO3)) directlyDecreases p(HGNC:NOS3) +tscript(p(HGNC:FOXO3)) decreases bp(GO:"cell proliferation") +p(HGNC:FOXO3) actsIn tscript(p(HGNC:FOXO3))