view test-data/angiogenesis_network.sif @ 11:cc00428a87f2 draft

Uploaded 01.06.2016
author computationaltranscriptomics
date Wed, 01 Jun 2016 10:14:02 -0400
parents f5e05d6382c8
children
line wrap: on
line source

p(HGNC:FGF9)	isA	p(PFH:"FGF Family")
p(HGNC:FGF10)	isA	p(PFH:"FGF Family")
p(HGNC:FGF18)	isA	p(PFH:"FGF Family")
p(HGNC:FGF1)	isA	p(PFH:"FGF Family")
p(HGNC:FGF2)	isA	p(PFH:"FGF Family")
p(HGNC:FGF16)	isA	p(PFH:"FGF Family")
p(HGNC:FGF5)	isA	p(PFH:"FGF Family")
p(HGNC:FGF7)	isA	p(PFH:"FGF Family")
p(HGNC:FGF8)	isA	p(PFH:"FGF Family")
p(PFH:"FGF Family")	increases	kin(p(PFH:"FGFR Family"))
p(HGNC:KNG1)	directlyIncreases	cat(p(HGNC:BDKRB1))
p(HGNC:KNG1)	directlyIncreases	cat(p(HGNC:BDKRB2))
p(HGNC:SIRT1)	actsIn	cat(p(HGNC:SIRT1))
p(HGNC:CXCL12)	directlyIncreases	cat(p(HGNC:CXCR4))
p(HGNC:NRP1)	actsIn	cat(p(HGNC:NRP1))
p(HGNC:NRP1)	increases	kin(p(HGNC:FLT1))
cat(p(HGNC:NRP1))	directlyIncreases	kin(p(HGNC:KDR))
p(HGNC:JAG1)	directlyIncreases	tscript(p(PFH:"NOTCH Family"))
p(HGNC:TGFB1)	isA	p(PFH:"TGFB Family")
p(HGNC:TGFB2)	isA	p(PFH:"TGFB Family")
p(PFH:"TGFB Family")	directlyIncreases	kin(p(HGNC:TGFBR2))
p(HGNC:PDGFRB)	isA	p(PFH:"PDGFR Family")
p(PFH:"PDGFR Family")	actsIn	kin(p(PFH:"PDGFR Family"))
p(HGNC:PDGFRA)	isA	p(PFH:"PDGFR Family")
p(HGNC:PDGFRB)	actsIn	kin(p(HGNC:PDGFRB))
p(HGNC:COL18A1)	decreases	kin(p(PFH:"MAPK p38 Family"))
p(HGNC:COL18A1)	decreases	kin(p(HGNC:MAPK3))
p(HGNC:COL18A1)	decreases	kin(p(HGNC:KDR))
p(HGNC:COL18A1)	decreases	kin(p(HGNC:PTK2))
p(HGNC:COL18A1)	decreases	kin(p(HGNC:MAPK1))
p(HGNC:BCL6B)	actsIn	cat(p(MGI:Bcl6b))
cat(p(MGI:Bcl6b))	increases	deg(p(MGI:Rbpj))
p(HGNC:EGLN2)	actsIn	cat(p(HGNC:EGLN2))
cat(p(HGNC:EGLN2))	increases	deg(p(HGNC:HIF1A))
p(HGNC:PRKAA1)	actsIn	kin(p(HGNC:PRKAA1))
kin(p(HGNC:PRKAA1))	increases	bp(GO:"blood vessel development")
p(HGNC:UNC5B)	actsIn	cat(p(HGNC:UNC5B))
cat(p(HGNC:UNC5B))	decreases	bp(GO:"patterning of blood vessels")
complex(p(HGNC:PDGFA),p(HGNC:PDGFB))	hasComponent	p(HGNC:PDGFA)
complex(p(HGNC:PDGFA),p(HGNC:PDGFB))	hasComponent	p(HGNC:PDGFB)
p(HGNC:TIE1)	actsIn	kin(p(HGNC:TIE1))
kin(p(HGNC:EGFR))	increases	kin(p(HGNC:MAPK3))
kin(p(HGNC:EGFR))	increases	kin(p(HGNC:MAPK1))
p(HGNC:TGFA)	directlyIncreases	kin(p(HGNC:EGFR))
deg(p(MGI:Rbpj))	directlyDecreases	p(HGNC:RBPJ)
a(CHEBI:"angiotensin II")	increases	p(HGNC:VEGFA)
a(CHEBI:"angiotensin II")	directlyIncreases	cat(p(HGNC:AGTR1))
a(CHEBI:"angiotensin II")	increases	tscript(p(HGNC:HIF1A))
a(CHEBI:"angiotensin II")	increases	p(HGNC:HIF1A)
p(HGNC:SHH)	increases	gtp(p(HGNC:RHOA))
p(HGNC:NOS3)	increases	bp(GO:angiogenesis)
p(HGNC:NOS3)	actsIn	cat(p(HGNC:NOS3))
p(HGNC:ANGPT2)	directlyDecreases	kin(p(HGNC:TEK))
p(HGNC:ANGPT2)	decreases	p(HGNC:ANGPT1)
p(HGNC:ANGPT2)	directlyDecreases	kin(p(HGNC:TIE1))
p(HGNC:ROBO4)	actsIn	cat(p(MGI:Robo4))
p(HGNC:OLR1)	increases	bp(GO:"patterning of blood vessels")
cat(p(HGNC:AGTR1))	increases	p(HGNC:OLR1)
p(HGNC:KLF2)	decreases	p(HGNC:HIF1A)
p(HGNC:KLF2)	actsIn	tscript(p(HGNC:KLF2))
kin(p(HGNC:PDGFRB))	increases	kin(p(HGNC:MAPK3))
kin(p(HGNC:PDGFRB))	increases	kin(p(HGNC:SRC))
kin(p(HGNC:PDGFRB))	increases	kin(p(HGNC:MAPK1))
p(HGNC:EPAS1)	actsIn	tscript(p(HGNC:EPAS1))
p(HGNC:BDKRB1)	actsIn	cat(p(HGNC:BDKRB1))
gtp(p(HGNC:RHOA))	directlyIncreases	kin(p(HGNC:ROCK1))
complex(p(HGNC:ECT2),p(HGNC:KLHL20))	hasComponent	p(HGNC:ECT2)
complex(p(HGNC:ECT2),p(HGNC:KLHL20))	increases	gtp(p(HGNC:RHOA))
complex(p(HGNC:ECT2),p(HGNC:KLHL20))	hasComponent	p(HGNC:KLHL20)
p(HGNC:ECT2)	increases	bp(GO:"patterning of blood vessels")
p(HGNC:MMP2)	actsIn	cat(p(HGNC:MMP2))
cat(p(HGNC:MMP2))	increases	p(HGNC:VEGFA)
p(HGNC:RAF1)	actsIn	kin(p(HGNC:RAF1))
kin(p(HGNC:RAF1))	increases	kin(p(HGNC:ROCK2))
p(HGNC:ENG)	increases	kin(p(HGNC:ACVRL1))
p(HGNC:ENG)	decreases	kin(p(HGNC:TGFBR1))
a(CHEBI:"sphingosine 1-phosphate")	increases	bp(GO:"patterning of blood vessels")
p(HGNC:FGFR1)	actsIn	kin(p(HGNC:FGFR1))
p(HGNC:FGFR2)	isA	p(PFH:"FGFR Family")
p(HGNC:FGFR3)	isA	p(PFH:"FGFR Family")
p(HGNC:FGFR1)	isA	p(PFH:"FGFR Family")
p(PFH:"FGFR Family")	actsIn	kin(p(PFH:"FGFR Family"))
p(HGNC:FGFR4)	isA	p(PFH:"FGFR Family")
p(HGNC:FGFR2)	actsIn	kin(p(HGNC:FGFR2))
p(HGNC:MAPK3)	actsIn	kin(p(HGNC:MAPK3))
p(HGNC:EP300)	directlyIncreases	tscript(p(HGNC:EPAS1))
p(HGNC:EP300)	actsIn	tscript(p(HGNC:EP300))
complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1))	hasComponent	p(HGNC:TCEB2)
complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1))	hasComponent	p(HGNC:CUL2)
complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1))	hasComponent	p(HGNC:TCEB1)
complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1))	increases	deg(p(HGNC:HIF1A))
complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1))	hasComponent	p(HGNC:VHL)
complex(p(HGNC:VHL),p(HGNC:TCEB1),p(HGNC:TCEB2),p(HGNC:CUL2),p(HGNC:RBX1))	hasComponent	p(HGNC:RBX1)
p(HGNC:EFNB2)	decreases	bp(GO:"patterning of blood vessels")
p(HGNC:EFNB2)	directlyIncreases	kin(p(HGNC:EPHB4))
p(HGNC:PXN)	increases	bp(GO:"cell migration")
kin(p(HGNC:PTK2))	increases	bp(GO:"cell migration")
p(HGNC:HEY1)	decreases	bp(GO:"patterning of blood vessels")
p(HGNC:SMAD4)	increases	p(HGNC:HEY2)
p(HGNC:SMAD4)	increases	p(HGNC:HEY1)
p(HGNC:SMAD4)	increases	bp(GO:"cell migration")
p(HGNC:SMAD4)	actsIn	tscript(p(HGNC:SMAD4))
p(HGNC:PLXND1)	actsIn	cat(p(MGI:Plxnd1))
p(HGNC:SMAD2)	actsIn	tscript(p(HGNC:SMAD2))
kin(p(PFH:"FGFR Family"))	increases	kin(p(PFH:?PIK3C Class IA Family?))
kin(p(PFH:"FGFR Family"))	increases	cat(p(HGNC:PLCG1))
kin(p(PFH:"FGFR Family"))	increases	kin(p(PFH:"MAPK p38 Family"))
tscript(p(HGNC:SMAD2))	decreases	bp(GO:"cell migration")
tscript(p(HGNC:SMAD2))	decreases	bp(GO:"cell proliferation")
p(HGNC:VTN)	directlyIncreases	cat(complex(p(HGNC:ITGAV),p(HGNC:ITGB3)))
tscript(p(HGNC:FOXO1))	decreases	bp(GO:angiogenesis)
tscript(p(HGNC:FOXO1))	directlyDecreases	p(HGNC:NOS3)
tscript(p(HGNC:FOXO1))	decreases	bp(GO:"cell migration")
tscript(p(HGNC:FOXO1))	increases	p(HGNC:ANGPT2)
p(HGNC:FOXO1)	actsIn	tscript(p(HGNC:FOXO1))
complex(p(HGNC:PDGFA),p(HGNC:PDGFA))	isA	p(PFH:"PDGF Family")
complex(p(HGNC:PDGFC),p(HGNC:PDGFC))	isA	p(PFH:"PDGF Family")
complex(p(HGNC:PDGFB),p(HGNC:PDGFB))	isA	p(PFH:"PDGF Family")
p(PFH:"PDGF Family")	increases	kin(p(PFH:"PDGFR Family"))
complex(p(HGNC:PDGFA),p(HGNC:PDGFA))	hasComponent	p(HGNC:PDGFA)
p(HGNC:NIN)	increases	bp(GO:"blood vessel development")
kin(p(HGNC:MAPK3))	increases	p(HGNC:PXN)
kin(p(HGNC:MAPK3))	increases	bp(GO:"cell proliferation")
p(HGNC:FGFR3)	actsIn	kin(p(HGNC:FGFR3))
p(HGNC:EDN1)	increases	tscript(p(HGNC:HIF1A))
kin(p(HGNC:TIE1))	decreases	bp(MESHPP:Apoptosis)
p(HGNC:ANGPT1)	directlyIncreases	kin(p(HGNC:TEK))
p(HGNC:ANGPT1)	directlyIncreases	kin(p(HGNC:TIE1))
p(HGNC:EGLN3)	actsIn	cat(p(HGNC:EGLN3))
deg(p(HGNC:HIF1A))	directlyDecreases	p(HGNC:HIF1A)
cat(p(HGNC:EGLN3))	increases	deg(p(HGNC:HIF1A))
p(HGNC:NCF1)	increases	bp(GO:"patterning of blood vessels")
cat(p(MGI:Plxnd1))	decreases	tscript(p(PFH:"NOTCH Family"))
p(HGNC:SEMA3E)	increases	cat(p(MGI:Plxnd1))
tscript(p(HGNC:SMAD1))	increases	bp(GO:"cell migration")
tscript(p(HGNC:SMAD1))	increases	bp(GO:"cell proliferation")
p(HGNC:SMAD1)	actsIn	tscript(p(HGNC:SMAD1))
complex(p(HGNC:ITGA2),p(HGNC:ITGB1))	increases	p(HGNC:DLL4)
complex(p(HGNC:ITGA2),p(HGNC:ITGB1))	increases	p(HGNC:FOXC2)
complex(p(HGNC:ITGA2),p(HGNC:ITGB1))	hasComponent	p(HGNC:ITGA2)
complex(p(HGNC:ITGA2),p(HGNC:ITGB1))	hasComponent	p(HGNC:ITGB1)
p(HGNC:IGF1R)	actsIn	kin(p(HGNC:IGF1R))
p(HGNC:PLCG1)	actsIn	cat(p(HGNC:PLCG1))
bp(GO:angiogenesis)	subProcessOf	bp(GO:"blood vessel development")
bp(GO:"patterning of blood vessels")	isA	bp(GO:angiogenesis)
bp(GO:"regulation of vascular permeability")	subProcessOf	bp(GO:angiogenesis)
cat(p(HGNC:NOS3))	increases	bp(GO:angiogenesis)
cat(p(HGNC:NOS3))	increases	bp(GO:"regulation of vascular permeability")
cat(p(HGNC:NOS3))	increases	bp(GO:"cell migration")
kin(p(HGNC:EPHB4))	decreases	bp(GO:"patterning of blood vessels")
p(HGNC:EPHB4)	actsIn	kin(p(HGNC:EPHB4))
p(HGNC:HEY2)	decreases	bp(GO:"patterning of blood vessels")
p(HGNC:KRIT1)	increases	p(HGNC:DLL4)
kin(p(HGNC:IGF1R))	directlyIncreases	kin(p(PFH:?PIK3C Class IA Family?))
kin(p(HGNC:IGF1R))	increases	kin(p(HGNC:SRC))
kin(p(HGNC:IGF1R))	increases	p(HGNC:HIF1A)
p(HGNC:IGF1)	increases	p(HGNC:HIF1A)
p(HGNC:IGF1)	directlyIncreases	kin(p(HGNC:IGF1R))
p(HGNC:TGFBR2)	actsIn	kin(p(HGNC:TGFBR2))
kin(p(HGNC:TGFBR2))	increases	kin(p(HGNC:ACVRL1))
kin(p(HGNC:TGFBR2))	directlyIncreases	kin(p(HGNC:TGFBR1))
p(HGNC:LGALS3)	increases	kin(p(HGNC:KDR))
p(HGNC:LGALS3)	increases	complex(p(HGNC:ITGAV),p(HGNC:ITGB3))
p(HGNC:LGALS3)	increases	bp(GO:"blood vessel development")
bp(GO:"cell proliferation")	subProcessOf	bp(GO:angiogenesis)
bp(GO:"cell migration")	subProcessOf	bp(GO:angiogenesis)
complex(p(HGNC:PDGFC),p(HGNC:PDGFC))	hasComponent	p(HGNC:PDGFC)
p(HGNC:FZD4)	increases	bp(GO:"patterning of blood vessels")
kin(p(HGNC:MET))	increases	kin(p(HGNC:MAPK1))
kin(p(HGNC:MET))	increases	kin(p(HGNC:MAPK3))
p(HGNC:HGF)	directlyIncreases	kin(p(HGNC:MET))
p(HGNC:FOXC2)	actsIn	tscript(p(HGNC:FOXC2))
kin(p(HGNC:TEK))	decreases	bp(MESHPP:Apoptosis)
kin(p(HGNC:TEK))	decreases	tscript(p(HGNC:FOXO3))
kin(p(HGNC:TEK))	increases	bp(GO:"cell migration")
kin(p(HGNC:TEK))	decreases	tscript(p(HGNC:FOXO1))
p(HGNC:TEK)	actsIn	kin(p(HGNC:TEK))
cat(p(HGNC:SIRT1))	increases	bp(GO:angiogenesis)
cat(p(HGNC:SIRT1))	increases	bp(GO:"patterning of blood vessels")
r(HGNC:MIR34A)	decreases	cat(p(HGNC:SIRT1))
p(HGNC:KDR)	actsIn	kin(p(HGNC:KDR))
kin(p(HGNC:PDGFRA))	increases	kin(p(HGNC:MAPK1))
kin(p(HGNC:PDGFRA))	increases	kin(p(HGNC:MAPK3))
p(HGNC:PDGFRA)	actsIn	kin(p(HGNC:PDGFRA))
p(HGNC:FGFR4)	actsIn	kin(p(HGNC:FGFR4))
complex(p(HGNC:PDGFB),p(HGNC:PDGFB))	hasComponent	p(HGNC:PDGFB)
complex(p(HGNC:ITGA6),p(HGNC:ITGB1))	hasComponent	p(HGNC:ITGB1)
complex(p(HGNC:ITGA6),p(HGNC:ITGB1))	increases	p(HGNC:DLL4)
complex(p(HGNC:ITGA6),p(HGNC:ITGB1))	hasComponent	p(HGNC:ITGA6)
tscript(p(HGNC:RBPJ))	directlyIncreases	p(HGNC:HEY2)
p(HGNC:RBPJ)	actsIn	tscript(p(HGNC:RBPJ))
p(HGNC:RBPJ)	directlyIncreases	tscript(p(PFH:"NOTCH Family"))
p(HGNC:VEGFB)	directlyIncreases	kin(p(HGNC:FLT1))
kin(p(HGNC:KDR))	increases	bp(GO:"cell migration")
kin(p(HGNC:KDR))	increases	bp(GO:"regulation of vascular permeability")
kin(p(HGNC:KDR))	increases	bp(GO:"cell proliferation")
kin(p(HGNC:KDR))	decreases	bp(MESHPP:Apoptosis)
p(HGNC:PDGFC)	directlyIncreases	kin(p(HGNC:KDR))
p(PFH:"AKT Family")	actsIn	kin(p(PFH:"AKT Family"))
p(HGNC:CDH5)	increases	kin(p(PFH:"AKT Family"))
tscript(p(HGNC:CREBBP))	increases	tscript(p(HGNC:HIF1A))
p(HGNC:CREBBP)	actsIn	tscript(p(HGNC:CREBBP))
p(HGNC:CREBBP)	directlyIncreases	tscript(p(HGNC:EPAS1))
kin(p(PFH:"MAPK p38 Family"))	increases	bp(GO:"cell migration")
p(PFH:"MAPK p38 Family")	actsIn	kin(p(PFH:"MAPK p38 Family"))
kin(p(HGNC:MAP2K1))	directlyIncreases	kin(p(HGNC:MAPK3))
kin(p(HGNC:MAP2K1))	directlyIncreases	kin(p(HGNC:MAPK1))
p(HGNC:MAP2K1)	actsIn	kin(p(HGNC:MAP2K1))
a(SCHEM:Diacylglycerol)	directlyIncreases	kin(p(PFH:"PRKC Family"))
p(HGNC:F2)	actsIn	cat(p(HGNC:F2))
cat(p(HGNC:F2))	increases	bp(GO:"blood vessel development")
p(HGNC:NR2F2)	actsIn	tscript(p(HGNC:NR2F2))
tscript(p(HGNC:NR2F2))	decreases	tscript(p(PFH:"NOTCH Family"))
kin(p(HGNC:ROCK2))	increases	bp(GO:"patterning of blood vessels")
p(HGNC:ROCK2)	actsIn	kin(p(HGNC:ROCK2))
p(HGNC:DLL4)	increases	tscript(p(PFH:"NOTCH Family"))
tscript(p(HGNC:FOXC2))	increases	p(HGNC:DLL4)
p(HGNC:VEGFA)	increases	bp(GO:"regulation of vascular permeability")
p(HGNC:VEGFA)	directlyIncreases	kin(p(HGNC:FLT1))
p(HGNC:VEGFA)	increases	kin(p(PFH:"MAPK p38 Family"))
p(HGNC:VEGFA)	directlyIncreases	kin(p(HGNC:KDR))
p(HGNC:VEGFA)	increases	p(HGNC:NOS3)
a(SCHEM:"kringle 5")	decreases	p(HGNC:VEGFA)
p(HGNC:GDF2)	directlyIncreases	kin(p(HGNC:ACVRL1))
cat(p(HGNC:HIF1AN))	directlyDecreases	tscript(p(HGNC:HIF1A))
p(HGNC:HIF1AN)	actsIn	cat(p(HGNC:HIF1AN))
p(HGNC:FLT1)	actsIn	kin(p(HGNC:FLT1))
kin(p(HGNC:FLT1))	increases	bp(GO:angiogenesis)
p(HGNC:TNXB)	increases	kin(p(HGNC:FLT1))
complex(p(HGNC:ETV6),p(HGNC:CTBP1))	hasComponent	p(HGNC:CTBP1)
complex(p(HGNC:ETV6),p(HGNC:CTBP1))	increases	bp(GO:"patterning of blood vessels")
complex(p(HGNC:ETV6),p(HGNC:CTBP1))	hasComponent	p(HGNC:ETV6)
kin(p(HGNC:TGFBR1))	directlyIncreases	tscript(p(HGNC:SMAD2))
kin(p(HGNC:TGFBR1))	directlyIncreases	tscript(p(HGNC:SMAD3))
kin(p(HGNC:TGFBR1))	increases	kin(p(PFH:"MAPK p38 Family"))
p(HGNC:TGFBR1)	actsIn	kin(p(HGNC:TGFBR1))
p(HGNC:KLHL20)	increases	bp(GO:"patterning of blood vessels")
p(HGNC:EIF4E)	actsIn	cat(p(HGNC:EIF4E))
p(HGNC:HIF1A)	actsIn	tscript(p(HGNC:HIF1A))
cat(p(HGNC:EIF4E))	increases	p(HGNC:HIF1A)
kin(p(PFH:"AKT Family"))	decreases	bp(MESHPP:Apoptosis)
kin(p(PFH:"AKT Family"))	increases	bp(GO:"patterning of blood vessels")
kin(p(PFH:"AKT Family"))	increases	cat(p(HGNC:NOS3))
kin(p(PFH:"AKT Family"))	increases	p(HGNC:PXN)
p(HGNC:ANXA2)	increases	kin(p(PFH:"AKT Family"))
cat(complex(p(HGNC:ITGAV),p(HGNC:ITGB3)))	increases	kin(p(HGNC:KDR))
complex(p(HGNC:ITGAV),p(HGNC:ITGB3))	actsIn	cat(complex(p(HGNC:ITGAV),p(HGNC:ITGB3)))
kin(p(PFH:"PRKC Family"))	increases	bp(GO:"regulation of vascular permeability")
kin(p(PFH:"PRKC Family"))	increases	kin(p(HGNC:MAPK3))
kin(p(PFH:"PRKC Family"))	increases	kin(p(HGNC:MAPK1))
p(PFH:"PRKC Family")	actsIn	kin(p(PFH:"PRKC Family"))
cat(p(HGNC:BDKRB2))	DefaultEdge	p(HGNC:VEGFA)
p(HGNC:BDKRB2)	actsIn	cat(p(HGNC:BDKRB2))
cat(p(HGNC:PLCG1))	increases	kin(p(PFH:"PRKC Family"))
kin(p(PFH:"PDGFR Family"))	increases	kin(p(PFH:?PIK3C Class IA Family?))
kin(p(PFH:"PDGFR Family"))	increases	kin(p(HGNC:MAPK1))
kin(p(PFH:"PDGFR Family"))	increases	cat(p(HGNC:PLCG1))
kin(p(HGNC:SRC))	directlyIncreases	kin(p(HGNC:PTK2))
kin(p(HGNC:SRC))	increases	cat(p(HGNC:PLCG1))
kin(p(HGNC:SRC))	increases	bp(GO:"regulation of vascular permeability")
p(HGNC:SRC)	actsIn	kin(p(HGNC:SRC))
tscript(p(HGNC:PPARA))	decreases	kin(p(PFH:"AKT Family"))
p(HGNC:PPARA)	actsIn	tscript(p(HGNC:PPARA))
p(HGNC:ITGB1BP1)	decreases	bp(GO:"patterning of blood vessels")
tscript(p(HGNC:SMAD3))	decreases	bp(GO:"cell proliferation")
tscript(p(HGNC:SMAD3))	decreases	bp(GO:"cell migration")
p(HGNC:SMAD3)	actsIn	tscript(p(HGNC:SMAD3))
tscript(p(HGNC:SMAD5))	increases	bp(GO:"cell proliferation")
tscript(p(HGNC:SMAD5))	increases	bp(GO:"cell migration")
p(HGNC:SMAD5)	actsIn	tscript(p(HGNC:SMAD5))
cat(p(HGNC:CXCR4))	increases	bp(GO:"patterning of blood vessels")
p(HGNC:CXCR4)	actsIn	cat(p(HGNC:CXCR4))
kin(p(PFH:?PIK3C Class IA Family?))	increases	kin(p(PFH:"AKT Family"))
complex(NCH:"p85/p110 PI3Kinase Complex")	actsIn	kin(p(PFH:?PIK3C Class IA Family?))
p(PFH:"NOTCH Family")	actsIn	tscript(p(PFH:"NOTCH Family"))
tscript(p(HGNC:EP300))	directlyIncreases	tscript(p(HGNC:HIF1A))
cat(p(HGNC:SHC1))	increases	kin(p(HGNC:MAPK1))
cat(p(HGNC:SHC1))	increases	kin(p(HGNC:MAPK3))
p(HGNC:SHC1)	actsIn	cat(p(HGNC:SHC1))
tscript(p(HGNC:NOTCH4))	increases	tscript(p(HGNC:RBPJ))
tscript(p(HGNC:NOTCH4))	decreases	bp(GO:"patterning of blood vessels")
p(HGNC:NOTCH4)	actsIn	tscript(p(HGNC:NOTCH4))
p(HGNC:S100A11)	increases	bp(GO:"patterning of blood vessels")
kin(p(HGNC:ACVRL1))	increases	tscript(p(HGNC:SMAD5))
kin(p(HGNC:ACVRL1))	increases	tscript(p(HGNC:SMAD1))
p(HGNC:ACVRL1)	actsIn	kin(p(HGNC:ACVRL1))
kin(p(HGNC:ROCK1))	increases	bp(GO:angiogenesis)
p(HGNC:ROCK1)	actsIn	kin(p(HGNC:ROCK1))
p(HGNC:RAP1B)	increases	bp(GO:"patterning of blood vessels")
p(HGNC:ARNT)	actsIn	tscript(p(HGNC:ARNT))
tscript(p(HGNC:HIF1A))	increases	p(HGNC:TGFA)
tscript(p(HGNC:HIF1A))	increases	p(HGNC:VEGFC)
tscript(p(HGNC:HIF1A))	increases	p(HGNC:ANGPT2)
tscript(p(HGNC:HIF1A))	increases	bp(GO:angiogenesis)
tscript(p(HGNC:HIF1A))	directlyIncreases	p(HGNC:VEGFA)
tscript(p(HGNC:HIF1A))	directlyIncreases	p(HGNC:PDGFB)
tscript(p(HGNC:HIF1A))	increases	p(HGNC:MMP2)
tscript(p(HGNC:HIF1A))	increases	p(HGNC:FGF2)
tscript(p(HGNC:HIF1A))	increases	p(HGNC:MMP9)
tscript(p(HGNC:HIF1A))	directlyIncreases	p(HGNC:PTGS2)
tscript(p(HGNC:HIF1A))	increases	p(HGNC:SERPINE1)
tscript(p(HGNC:HIF1A))	increases	p(HGNC:ANGPT1)
tscript(p(HGNC:ARNT))	directlyIncreases	tscript(p(HGNC:HIF1A))
tscript(p(HGNC:ARNT))	directlyIncreases	tscript(p(HGNC:EPAS1))
cat(p(HGNC:EGLN1))	increases	deg(p(HGNC:HIF1A))
p(HGNC:EGLN1)	actsIn	cat(p(HGNC:EGLN1))
p(HGNC:MMP14)	actsIn	cat(p(HGNC:MMP14))
cat(p(HGNC:MMP14))	increases	bp(GO:"blood vessel development")
tscript(p(PFH:"NOTCH Family"))	increases	p(HGNC:HEY2)
tscript(p(PFH:"NOTCH Family"))	increases	p(HGNC:HEY1)
tscript(p(HGNC:NOTCH4))	isA	tscript(p(PFH:"NOTCH Family"))
tscript(p(PFH:"NOTCH Family"))	decreases	bp(GO:"patterning of blood vessels")
p(HGNC:EGFL7)	directlyDecreases	tscript(p(PFH:"NOTCH Family"))
cat(p(MGI:Robo4))	decreases	bp(GO:"blood vessel development")
p(HGNC:SLIT2)	increases	cat(p(MGI:Robo4))
kin(p(HGNC:MAPK1))	increases	p(HGNC:PXN)
kin(p(HGNC:MAPK1))	increases	bp(GO:"cell proliferation")
p(HGNC:MAPK1)	actsIn	kin(p(HGNC:MAPK1))
tscript(p(HGNC:FOXO3))	decreases	bp(GO:"cell migration")
tscript(p(HGNC:FOXO3))	directlyDecreases	p(HGNC:NOS3)
tscript(p(HGNC:FOXO3))	decreases	bp(GO:"cell proliferation")
p(HGNC:FOXO3)	actsIn	tscript(p(HGNC:FOXO3))