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127
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128 <body lang=EN-US style='tab-interval:.5in'>
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129
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130 <div class=WordSection1>
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131
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132 <p class=MsoNoSpacing style='text-align:justify'><b><u><span lang=EN-GB
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133 style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:
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134 EN-GB'>Gene frequencies tab</span></u></b></p>
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135
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136 <p class=MsoNormal style='margin-bottom:0in;margin-bottom:.0001pt;text-align:
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137 justify;line-height:normal'><span lang=EN-GB style='font-size:12.0pt;
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138 font-family:"Times New Roman","serif";mso-ansi-language:EN-GB'>This tab gives
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139 information on the frequency of V, D and J gene usage. <o:p></o:p></span></p>
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140
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141 <p class=MsoNormal style='margin-bottom:0in;margin-bottom:.0001pt;text-align:
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142 justify;line-height:normal'><o:p> </o:p></p>
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143
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144 <p class=MsoNoSpacing style='text-align:justify'><b><span lang=EN-GB
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145 style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:
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146 EN-GB'>Graphs</span></b></p>
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147
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148 <p class=MsoNormal style='margin-bottom:0in;margin-bottom:.0001pt;text-align:
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149 justify;line-height:normal'><u><span lang=EN-GB style='font-size:12.0pt;
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150 font-family:"Times New Roman","serif";mso-ansi-language:EN-GB'>Distribution of
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151 V gene families<o:p></o:p></span></u></p>
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152
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153 <p class=MsoNoSpacing style='text-align:justify'><a name="OLE_LINK121"></a><a
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154 name="OLE_LINK123"></a><a name="OLE_LINK122"></a><span style='mso-bookmark:
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155 OLE_LINK121'><span lang=EN-GB style='font-size:12.0pt;font-family:"Times New Roman","serif";
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156 mso-ansi-language:EN-GB'>Bar graph showing the frequency of V gene family usage
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157 in all uploaded donors. </span></span><span lang=EN-GB style='font-size:12.0pt;
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158 font-family:"Times New Roman","serif";mso-ansi-language:EN-GB'><o:p></o:p></span></p>
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159
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160 <p class=MsoNoSpacing style='text-align:justify'><o:p> </o:p></p>
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161
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162 <p class=MsoNormal style='margin-bottom:0in;margin-bottom:.0001pt;text-align:
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163 justify;line-height:normal'><u><span lang=EN-GB style='font-size:12.0pt;
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164 font-family:"Times New Roman","serif";mso-ansi-language:EN-GB'>Relative
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165 frequency of V gene usage<o:p></o:p></span></u></p>
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166
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167 <p class=MsoNoSpacing style='text-align:justify'><a name="OLE_LINK124"></a><a
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168 name="OLE_LINK126"></a><a name="OLE_LINK125"></a><span style='mso-bookmark:
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169 OLE_LINK124'><span lang=EN-GB style='font-size:12.0pt;font-family:"Times New Roman","serif";
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170 mso-ansi-language:EN-GB'>Bar graph showing the frequency of V genes in all
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171 uploaded donors. The order of the V genes on the x-axis can be altered by
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172 altering the “<span style='color:black;background:white'>Order of V(D)J genes
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173 in graphs” filter on the main page of the Immune repertoire pipeline.</span></span></span><span
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174 lang=EN-GB style='font-size:12.0pt;font-family:"Times New Roman","serif";
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175 color:black;background:white;mso-ansi-language:EN-GB'><o:p></o:p></span></p>
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176
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177 <p class=MsoNoSpacing style='text-align:justify'><o:p> </o:p></p>
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178
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179 <p class=MsoNormal style='margin-bottom:0in;margin-bottom:.0001pt;text-align:
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180 justify;line-height:normal'><u><span lang=EN-GB style='font-size:12.0pt;
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181 font-family:"Times New Roman","serif";mso-ansi-language:EN-GB'>Relative
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182 frequency of D gene usage<o:p></o:p></span></u></p>
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183
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184 <p class=MsoNoSpacing style='text-align:justify'><span lang=EN-GB
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185 style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:
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186 EN-GB'>Bar graph showing the frequency of D genes in all uploaded donors. The
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187 order of the D genes on the x-axis can be altered by altering the “<span
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188 style='color:black;background:white'>Order of V(D)J genes in graphs” filter on
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189 the main page of the Immune repertoire pipeline.<o:p></o:p></span></span></p>
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190
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191 <p class=MsoNoSpacing style='text-align:justify'><o:p> </o:p></p>
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192
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193 <p class=MsoNormal style='margin-bottom:0in;margin-bottom:.0001pt;text-align:
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194 justify;line-height:normal'><u><span lang=EN-GB style='font-size:12.0pt;
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195 font-family:"Times New Roman","serif";mso-ansi-language:EN-GB'>Relative
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196 frequency of J gene usage<o:p></o:p></span></u></p>
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197
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198 <p class=MsoNoSpacing style='text-align:justify'><span lang=EN-GB
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199 style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:
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200 EN-GB'>Bar graph showing the frequency of J genes in all uploaded donors. The
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201 order of the J genes on the x-axis can be altered by altering the “<span
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202 style='color:black;background:white'>Order of V(D)J genes in graphs” filter on
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203 the main page of the Immune repertoire pipeline.<o:p></o:p></span></span></p>
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204
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205 <p class=MsoNoSpacing style='text-align:justify'><o:p> </o:p></p>
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206
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207 <p class=MsoNormal style='margin-bottom:0in;margin-bottom:.0001pt;text-align:
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208 justify;line-height:normal'><u><span style='font-size:12.0pt;font-family:"Times New Roman","serif"'>D
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209 reading frame<o:p></o:p></span></u></p>
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210
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211 <p class=MsoNoSpacing style='text-align:justify'><span lang=EN-GB
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212 style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:
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213 EN-GB'>Bar graph visualizing the frequency by which each D reading frame is
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214 used in each donor.</span></p>
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215
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216 </div>
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