| 
18
 | 
     1 <html>
 | 
| 
 | 
     2 
 | 
| 
 | 
     3 <head>
 | 
| 
 | 
     4 <meta http-equiv=Content-Type content="text/html; charset=windows-1252">
 | 
| 
 | 
     5 <meta name=Generator content="Microsoft Word 14 (filtered)">
 | 
| 
 | 
     6 <style>
 | 
| 
 | 
     7 <!--
 | 
| 
 | 
     8  /* Font Definitions */
 | 
| 
 | 
     9  @font-face
 | 
| 
 | 
    10 	{font-family:Calibri;
 | 
| 
 | 
    11 	panose-1:2 15 5 2 2 2 4 3 2 4;}
 | 
| 
 | 
    12  /* Style Definitions */
 | 
| 
 | 
    13  p.MsoNormal, li.MsoNormal, div.MsoNormal
 | 
| 
 | 
    14 	{margin-top:0in;
 | 
| 
 | 
    15 	margin-right:0in;
 | 
| 
 | 
    16 	margin-bottom:10.0pt;
 | 
| 
 | 
    17 	margin-left:0in;
 | 
| 
 | 
    18 	line-height:115%;
 | 
| 
 | 
    19 	font-size:11.0pt;
 | 
| 
 | 
    20 	font-family:"Calibri","sans-serif";}
 | 
| 
 | 
    21 p.MsoNoSpacing, li.MsoNoSpacing, div.MsoNoSpacing
 | 
| 
 | 
    22 	{margin:0in;
 | 
| 
 | 
    23 	margin-bottom:.0001pt;
 | 
| 
 | 
    24 	font-size:11.0pt;
 | 
| 
 | 
    25 	font-family:"Calibri","sans-serif";}
 | 
| 
 | 
    26 .MsoChpDefault
 | 
| 
 | 
    27 	{font-family:"Calibri","sans-serif";}
 | 
| 
 | 
    28 .MsoPapDefault
 | 
| 
 | 
    29 	{margin-bottom:10.0pt;
 | 
| 
 | 
    30 	line-height:115%;}
 | 
| 
 | 
    31 @page WordSection1
 | 
| 
 | 
    32 	{size:8.5in 11.0in;
 | 
| 
 | 
    33 	margin:1.0in 1.0in 1.0in 1.0in;}
 | 
| 
 | 
    34 div.WordSection1
 | 
| 
 | 
    35 	{page:WordSection1;}
 | 
| 
 | 
    36 -->
 | 
| 
 | 
    37 </style>
 | 
| 
 | 
    38 
 | 
| 
 | 
    39 </head>
 | 
| 
 | 
    40 
 | 
| 
 | 
    41 <body lang=EN-US>
 | 
| 
 | 
    42 
 | 
| 
 | 
    43 <div class=WordSection1>
 | 
| 
 | 
    44 
 | 
| 
 | 
    45 <p class=MsoNormal style='margin-bottom:0in;margin-bottom:.0001pt;text-align:
 | 
| 
 | 
    46 justify;line-height:normal'><span lang=EN-GB style='font-size:12.0pt;
 | 
| 
 | 
    47 font-family:"Times New Roman","serif"'>This tab gives information on the
 | 
| 
 | 
    48 frequency of V, D and J gene usage. </span></p>
 | 
| 
 | 
    49 
 | 
| 
 | 
    50 <p class=MsoNoSpacingCxSpMiddle style='text-align:justify'><b><span lang=EN-GB
 | 
| 
 | 
    51 style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Graphs</span></b></p>
 | 
| 
 | 
    52 
 | 
| 
 | 
    53 <p class=MsoNormalCxSpFirst style='margin-bottom:0in;margin-bottom:.0001pt;
 | 
| 
 | 
    54 text-align:justify;line-height:normal'><u><span lang=EN-GB style='font-size:
 | 
| 
 | 
    55 12.0pt;font-family:"Times New Roman","serif"'>Distribution of V gene families</span></u></p>
 | 
| 
 | 
    56 
 | 
| 
 | 
    57 <p class=MsoNormalCxSpMiddle style='margin-bottom:0in;margin-bottom:.0001pt;
 | 
| 
 | 
    58 text-align:justify;line-height:normal'><a name="OLE_LINK123"></a><a
 | 
| 
 | 
    59 name="OLE_LINK122"></a><a name="OLE_LINK121"><span lang=EN-GB style='font-size:
 | 
| 
 | 
    60 12.0pt;font-family:"Times New Roman","serif"'>Bar graph showing the frequency
 | 
| 
 | 
    61 of V gene family usage in all uploaded donors. </span></a></p>
 | 
| 
 | 
    62 
 | 
| 
 | 
    63 <p class=MsoNormalCxSpMiddle style='margin-bottom:0in;margin-bottom:.0001pt;
 | 
| 
 | 
    64 text-align:justify;line-height:normal'><u><span lang=EN-GB style='font-size:
 | 
| 
 | 
    65 12.0pt;font-family:"Times New Roman","serif"'>Relative frequency of V gene
 | 
| 
 | 
    66 usage</span></u></p>
 | 
| 
 | 
    67 
 | 
| 
 | 
    68 <p class=MsoNormalCxSpLast style='margin-bottom:0in;margin-bottom:.0001pt;
 | 
| 
 | 
    69 text-align:justify;line-height:normal'><a name="OLE_LINK126"></a><a
 | 
| 
 | 
    70 name="OLE_LINK125"></a><a name="OLE_LINK124"><span lang=EN-GB style='font-size:
 | 
| 
 | 
    71 12.0pt;font-family:"Times New Roman","serif"'>Bar graph showing the frequency
 | 
| 
 | 
    72 of V genes in all uploaded donors. The order of the V genes on the x-axis can
 | 
| 
 | 
    73 be altered by altering the “<span style='color:black;background:white'>Order of
 | 
| 
 | 
    74 V(D)J genes in graphs” filter on the main page of the Immune repertoire
 | 
| 
 | 
    75 pipeline.</span></span></a></p>
 | 
| 
 | 
    76 
 | 
| 
 | 
    77 <p class=MsoNoSpacingCxSpLast style='text-align:justify'><a name="OLE_LINK129"></a><a
 | 
| 
 | 
    78 name="OLE_LINK128"></a><a name="OLE_LINK127"><u><span lang=EN-GB
 | 
| 
 | 
    79 style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Relative
 | 
| 
 | 
    80 frequency of D gene usage</span></u></a></p>
 | 
| 
 | 
    81 
 | 
| 
 | 
    82 <p class=MsoNormalCxSpFirst style='margin-bottom:0in;margin-bottom:.0001pt;
 | 
| 
 | 
    83 text-align:justify;line-height:normal'><span lang=EN-GB style='font-size:12.0pt;
 | 
| 
 | 
    84 font-family:"Times New Roman","serif"'>Bar graph showing the frequency of D
 | 
| 
 | 
    85 genes in all uploaded donors. The order of the D genes on the x-axis can be
 | 
| 
 | 
    86 altered by altering the “<span style='color:black;background:white'>Order of
 | 
| 
 | 
    87 V(D)J genes in graphs” filter on the main page of the Immune repertoire
 | 
| 
 | 
    88 pipeline.</span></span></p>
 | 
| 
 | 
    89 
 | 
| 
 | 
    90 <p class=MsoNoSpacing style='text-align:justify'><u><span lang=EN-GB
 | 
| 
 | 
    91 style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Relative
 | 
| 
 | 
    92 frequency of J gene usage</span></u></p>
 | 
| 
 | 
    93 
 | 
| 
 | 
    94 <p class=MsoNormalCxSpFirst style='margin-bottom:0in;margin-bottom:.0001pt;
 | 
| 
 | 
    95 text-align:justify;line-height:normal'><span lang=EN-GB style='font-size:12.0pt;
 | 
| 
 | 
    96 font-family:"Times New Roman","serif"'>Bar graph showing the frequency of J
 | 
| 
 | 
    97 genes in all uploaded donors. The order of the J genes on the x-axis can be
 | 
| 
 | 
    98 altered by altering the “<span style='color:black;background:white'>Order of
 | 
| 
 | 
    99 V(D)J genes in graphs” filter on the main page of the Immune repertoire
 | 
| 
 | 
   100 pipeline.</span></span></p>
 | 
| 
 | 
   101 
 | 
| 
 | 
   102 </div>
 | 
| 
 | 
   103 
 | 
| 
 | 
   104 </body>
 | 
| 
 | 
   105 
 | 
| 
 | 
   106 </html>
 |