Mercurial > repos > ebi-gxa > score_genes_aucell

--- a/decoupler_pathway_inference.py	Wed Oct 30 14:01:13 2024 +0000
+++ b/decoupler_pathway_inference.py	Fri Nov 29 11:34:02 2024 +0000
@@ -10,9 +10,13 @@

 # add AnnData input file option
 parser.add_argument(
-    "-i", "--input_anndata", help="AnnData input file", required=True
+    "-i", "--input",
+    help=(
+        "AnnData or table input file. Table input is meant for a single "
+        "comparison, not gene x cells"
+    ),
+    required=True
 )
-
 # add network input file option
 parser.add_argument(
     "-n", "--input_network", help="Network input file", required=True
@@ -34,6 +38,28 @@
     default=None,
 )

+# Column for stat to use when providing a table
+parser.add_argument(
+    "--stat",
+    help="Stat to use when providing a table. Default is 'log2FC'.",
+    default="log2FC",
+)
+# Optional column for p-value or FDR in the table
+parser.add_argument(
+    "--p_value_column",
+    required=False,
+    help="Column name in the table with p-values or FDRs.",
+    default=None,
+)
+# Optional column for FDR threshold when given a table
+parser.add_argument(
+    "--p_value_threshold",
+    required=False,
+    type=float,
+    help="Column name in the table with FDRs.",
+    default=0.05
+)
+
 # Column name in net with source nodes
 parser.add_argument(
     "-s",
@@ -93,8 +119,15 @@
 if args.output is None:
     raise ValueError("Please specify either -o or --output")

-# read in the AnnData input file
-adata = ad.read_h5ad(args.input_anndata)
+# detect based on input file extension if the input file is AnnData or matrix
+if args.input.endswith(".h5ad"):
+    input_type = "AnnData"
+elif args.input.endswith(".tsv") or args.input.endswith(".csv"):
+    input_type = "matrix"
+else:
+    raise ValueError(
+        "Invalid input file. Please provide a valid AnnData or matrix file."
+    )

 # read in the input file network input file
 network = pd.read_csv(args.input_network, sep="\t")
@@ -108,17 +141,32 @@
         "Source, target, and weight columns are not present in the network"
     )

-
 print(type(args.min_n))

-if args.var_gene_symbols_field and args.var_gene_symbols_field in adata.var.columns:
-    # Storing index in a column called 'index_bak'
-    adata.var['index_bak'] = adata.var.index
-    adata.var.set_index(args.var_gene_symbols_field, inplace=True)
+if input_type == "AnnData":
+    # read in the AnnData input file
+    adata = ad.read_h5ad(args.input)

+    if args.var_gene_symbols_field and args.var_gene_symbols_field in adata.var.columns:
+        # Storing index in a column called 'index_bak'
+        adata.var['index_bak'] = adata.var.index
+        adata.var.set_index(args.var_gene_symbols_field, inplace=True)
+else:
+    # read in the matrix input file, genes in rows and columns for stats
+    adata = pd.read_csv(args.input, sep="\t", index_col=0)
+    if args.stat not in adata.columns:
+        raise ValueError(f"Stat column {args.stat} not found in input table header.")
+    if args.p_value_column and args.p_value_column not in adata.columns:
+        raise ValueError(
+            f"P-value column {args.p_value_column} not found in input table header."
+        )
+    if args.p_value_column and args.p_value_threshold is not None:
+        adata = adata[adata[args.p_value_column] <= args.p_value_threshold]
+
+    adata = adata[[args.stat]].T

 if args.method == "mlm":
-    dc.run_mlm(
+    res = dc.run_mlm(
         mat=adata,
         net=network,
         source=args.source,
@@ -129,24 +177,19 @@
         use_raw=args.use_raw,
     )

-    if args.output is not None:
-        # write adata.obsm[mlm_key] and adata.obsm[mlm_pvals_key] to the
-        # output network files
-        combined_df = pd.concat(
-            [adata.obsm["mlm_estimate"], adata.obsm["mlm_pvals"]], axis=1
-        )
-
-        # Save the combined dataframe to a file
-        combined_df.to_csv(args.output + ".tsv", sep="\t")
-
-    # if args.activities_path is specified, generate the activities AnnData
-    # and save the AnnData object to the specified path
-    if args.activities_path is not None:
-        acts = dc.get_acts(adata, obsm_key="mlm_estimate")
-        acts.write_h5ad(args.activities_path)
-
 elif args.method == "ulm":
-    dc.run_ulm(
+    res = dc.run_ulm(
+        mat=adata,
+        net=network,
+        source=args.source,
+        target=args.target,
+        weight=args.weight,
+        verbose=True,
+        min_n=args.min_n,
+        use_raw=args.use_raw,
+    )
+elif args.method == "consensus":
+    res = dc.run_consensus(
         mat=adata,
         net=network,
         source=args.source,
@@ -157,18 +200,31 @@
         use_raw=args.use_raw,
     )

-    if args.output is not None:
-        # write adata.obsm[mlm_key] and adata.obsm[mlm_pvals_key] to the
-        # output network files
+if args.output is not None:
+    # write adata.obsm[mlm_key] and adata.obsm[mlm_pvals_key] to the
+    # output network files
+    if input_type == "AnnData":
         combined_df = pd.concat(
-            [adata.obsm["ulm_estimate"], adata.obsm["ulm_pvals"]], axis=1
+            [adata.obsm[f"{args.method}_estimate"],
+             adata.obsm[f"{args.method}_pvals"]], axis=1
         )
+    else:
+        tf_est, tf_pvals = res
+        combined_df = pd.DataFrame(
+            {
+                # index is written, so no need for the set names
+                f"{args.method}_estimate": tf_est.iloc[0],
+                f"{args.method}_pvals": tf_pvals.iloc[0],
+            }
+        )
+        # sort ascending on the p-values
+        combined_df.sort_values(by=f"{args.method}_pvals", inplace=True)

-        # Save the combined dataframe to a file
-        combined_df.to_csv(args.output + ".tsv", sep="\t")
+    # Save the combined dataframe to a file
+    combined_df.to_csv(args.output + ".tsv", sep="\t")

-    # if args.activities_path is specified, generate the activities AnnData
-    # and save the AnnData object to the specified path
-    if args.activities_path is not None:
-        acts = dc.get_acts(adata, obsm_key="ulm_estimate")
-        acts.write_h5ad(args.activities_path)
+# if args.activities_path is specified, generate the activities AnnData
+# and save the AnnData object to the specified path
+if args.activities_path is not None and input_type == "AnnData":
+    acts = dc.get_acts(adata, obsm_key=f"{args.method}_estimate")
+    acts.write_h5ad(args.activities_path)
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/diff_exp_result.tab	Fri Nov 29 11:34:02 2024 +0000
@@ -0,0 +1,16407 @@
+Gene	log2FoldChange	pvalue	padj
+DOK6	0.51	1.861e-08	0.0003053
+TBX5	-2.129	5.655e-08	0.0004191
+SLC32A1	0.9003	7.664e-08	0.0004191
+IFITM1	-1.687	3.735e-06	0.006809
+NUP93	0.3659	3.373e-06	0.006809
+EMILIN2	1.534	2.976e-06	0.006809
+TPX2	-0.9974	2.097e-06	0.006809
+LAMA2	-1.425	2.39e-06	0.006809
+CAV2	-1.052	3.213e-06	0.006809
+TNN	-1.658	8.973e-06	0.01472
+POU3F4	1.181	1.062e-05	0.01584
+COL13A1	-1.647	1.394e-05	0.01592
+IFITM3	-1.61	1.202e-05	0.01592
+SHISA3	-1.477	1.31e-05	0.01592
+LOC285954	1.05	1.456e-05	0.01592
+VEPH1	1.137	2.211e-05	0.02267
+ARHGAP29	-1.526	3.675e-05	0.03547
+KIAA1755	-1.562	3.972e-05	0.0362
+LAMC3	-1.563	4.29e-05	0.03704
+ITM2A	-1.398	4.972e-05	0.04078
+DTHD1	1.54	5.594e-05	0.04371
+RBMS1	-0.9139	6.688e-05	0.04988
+CEBPD	-1.202	7.859e-05	0.05606
+DMBX1	-1.425	9.529e-05	0.06486
+PAPLN	-1.253	9.883e-05	0.06486
+ADM	-1.357	0.0001089	0.06872
+COL2A1	-1.187	0.0001424	0.07794
+HS3ST3A1	-1.004	0.0001388	0.07794
+DYSF	-1.03	0.0001425	0.07794
+PI16	1.495	0.0001297	0.07794
+CDC42EP5	-1.355	0.0001581	0.08146
+SLC12A8	-0.9425	0.0001589	0.08146
+ZNF391	-1.024	0.0001913	0.09512
+GALNTL2	1.075	0.0002298	0.1109
+C4orf45	1.288	0.0002472	0.1159
+KIF18B	-0.8849	0.0002551	0.1162
+KIF20A	-0.9505	0.0002972	0.1318
+PDE1B	1.053	0.0003356	0.1449
+BCAN	1.117	0.0003698	0.1477
+APLNR	-1.365	0.000378	0.1477
+CILP	-1.11	0.0003582	0.1477
+TEC	-1.373	0.0003701	0.1477
+KLF5	-0.8177	0.0004159	0.1578
+ACSS2	-0.5578	0.0004232	0.1578
+RAPGEF2	0.3371	0.0004513	0.1645
+C1orf51	-0.6451	0.0005237	0.1665
+IGF2-AS1	-1.235	0.0005835	0.1665
+RPLP0P2	-1.096	0.0005689	0.1665
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+CFLAR	-0.9694	0.0005598	0.1665
+BHLHE40	-1.127	0.0004785	0.1665
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+BHLHB9	0.4738	0.002441	0.3337
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+CSDA	-0.7633	0.002833	0.35
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+COL8A1	-1.171	0.002841	0.35
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+A2M	-1.048	0.00719	0.4935
+C12orf34	0.596	0.007283	0.4935
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+LOC150622	0.9708	0.007286	0.4935
+LOC100130451	0.9622	0.007342	0.4935
+SNAI1	-1.023	0.00725	0.4935
+BCL2L13	0.1979	0.007251	0.4935
+DSP	-0.9805	0.007197	0.4935
+CERS2	-0.484	0.007538	0.4946
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+UGGT2	-0.5188	0.008106	0.5161
+HSDL1	0.2664	0.008179	0.5161
+RBPMS	-0.7992	0.008079	0.5161
+CD164	-0.757	0.00828	0.5205
+L1TD1	-1.033	0.008321	0.5206
+PRDX6	-0.5123	0.008346	0.5206
+FAM46C	-0.9537	0.008391	0.5215
+ADAM33	-0.9939	0.008549	0.5293
+TLK1	-0.2367	0.00876	0.5403
+KCNK2	0.6097	0.008794	0.5404
+POLR3A	0.2868	0.009062	0.5426
+GANAB	-0.3036	0.009048	0.5426
+CPOX	-0.3403	0.009023	0.5426
+MICA	-0.859	0.008998	0.5426
+POU3F2	0.4784	0.008894	0.5426
+AUTS2	0.39	0.009006	0.5426
+SYPL1	-0.4891	0.008937	0.5426
+MSN	-0.3958	0.009132	0.5448
+ZCCHC24	-0.9672	0.009169	0.545
+GSTO1	-0.4109	0.009215	0.5458
+XDH	0.954	0.00933	0.5486
+PABPC1L2B	0.8795	0.009309	0.5486
+POGK	0.2803	0.009736	0.5624
+EFEMP2	-0.9948	0.009655	0.5624
+MYADM	-0.7661	0.009726	0.5624
+ORC4	0.3291	0.009609	0.5624
+INSM1	0.5511	0.009701	0.5624
+C14orf149	-0.5111	0.01024	0.5647
+MFGE8	-0.6672	0.01011	0.5647
+CEACAM1	-0.981	0.01007	0.5647
+PLEKHA4	-0.8802	0.01021	0.5647
+MERTK	-0.7662	0.009946	0.5647
+MARCH4	0.6728	0.0103	0.5647
+GBX2	0.8828	0.01022	0.5647
+SDC4	-0.6983	0.009882	0.5647
+ITGA9	-0.944	0.01008	0.5647
+SCN5A	-0.9351	0.01019	0.5647
+MFI2	-0.8345	0.01026	0.5647
+RAB11FIP1	-0.7027	0.01033	0.5647
+TPD52	-0.7816	0.01023	0.5647
+KIAA2022	0.5636	0.01014	0.5647
+TCEAL6	0.8956	0.01016	0.5647
+MORC4	-0.9271	0.0103	0.5647
+POC1B	-0.3673	0.01042	0.5659
+MRC2	-0.6332	0.01039	0.5659
+KCTD6	-0.3616	0.01053	0.57
+MEX3A	0.3088	0.01065	0.5708
+ACTN1	-0.7487	0.01061	0.5708
+TICAM1	-0.8589	0.01061	0.5708
+NPC2	-0.6069	0.01078	0.5721
+COL6A6	-0.969	0.01076	0.5721
+ZC3HAV1	-0.6569	0.01073	0.5721
+OAF	-0.7698	0.01096	0.5782
+RNASE4	-0.9059	0.01096	0.5782
+CYBASC3	-0.4846	0.011	0.5784
+CSRNP1	-0.5808	0.01106	0.5795
+HLA-B	-0.868	0.01116	0.5831
+ZNF689	0.2551	0.01125	0.5858
+SP9	0.9371	0.01128	0.5858
+WASF2	-0.6745	0.0114	0.5886
+SLFN12	-0.9886	0.01141	0.5886
+FLNA	-0.614	0.01146	0.5896
+FREM2	-0.9473	0.01154	0.5914
+PDIA3P	-0.3457	0.01185	0.5983
+GAS2L2	0.9302	0.01185	0.5983
+FERMT1	-0.9868	0.01187	0.5983
+SEC14L6	-0.9848	0.01193	0.5983
+CSPG5	0.6937	0.01186	0.5983
+C7orf41	0.3768	0.0119	0.5983
+MYBL1	-0.5962	0.01188	0.5983
+HJURP	-0.8059	0.01202	0.6014
+SH3BP5L	0.2129	0.01241	0.6059
+DDN	0.7147	0.01244	0.6059
+RAB35	0.2403	0.0124	0.6059
+RBPMS2	-0.6679	0.01232	0.6059
+MYLK3	0.8447	0.01234	0.6059
+ZFYVE20	0.2118	0.01226	0.6059
+ACSL6	0.6116	0.01224	0.6059
+PCDHGB1	-0.8347	0.01224	0.6059
+SYNPO	-0.9788	0.01241	0.6059
+ARHGAP17	-0.3736	0.01264	0.6065
+ETFB	0.505	0.01264	0.6065
+CRYBA4	-0.9657	0.01264	0.6065
+F2RL2	-0.9768	0.01251	0.6065
+STOM	-0.743	0.01264	0.6065
+C15orf59	0.6647	0.01277	0.6072
+NCAN	0.5804	0.01274	0.6072
+GPC4	-0.7703	0.01277	0.6072
+DES	-0.9714	0.01286	0.6096
+LEPREL2	-0.7969	0.01293	0.6112
+GRIN2A	0.6614	0.01302	0.6122
+FAM84B	0.6649	0.01301	0.6122
+CCND1	-0.5753	0.01313	0.6154
+SEPN1	-0.3657	0.01325	0.6177
+CGN	-0.7533	0.01333	0.6177
+BAG5	0.2349	0.01328	0.6177
+WWC2	-0.4373	0.01333	0.6177
+ANO6	-0.5992	0.01349	0.6233
+FZD4	-0.8521	0.01357	0.6255
+DIAPH3	-0.7778	0.01367	0.6284
+RUNX1	-0.9599	0.01374	0.6298
+NTS	0.8462	0.01385	0.631
+TBC1D8B	-0.9647	0.01381	0.631
+GP5	-0.9553	0.01392	0.6324
+ZNF547	0.5118	0.01398	0.6336
+B2M	-0.7496	0.01412	0.6364
+GPANK1	0.3544	0.01412	0.6364
+MYCL1	0.564	0.01419	0.6377
+C15orf42	-0.7478	0.01427	0.6397
+PTP4A3	-0.6072	0.01435	0.6417
+TGFB1I1	-0.8773	0.01443	0.6434
+PTGDR2	-0.9554	0.0147	0.6467
+RARG	-0.9358	0.01459	0.6467
+RAB34	-0.8674	0.01459	0.6467
+DSC2	-0.6871	0.0147	0.6467
+FZD5	-0.654	0.01478	0.6467
+KLHL18	0.249	0.01466	0.6467
+PCDHGB5	-0.956	0.01477	0.6467
+EFNA1	-0.7949	0.01488	0.6476
+KIAA0087	0.9528	0.01488	0.6476
+AURKA	-0.652	0.01506	0.6535
+GAL3ST3	0.4134	0.01511	0.654
+WNT7A	0.7548	0.01515	0.6543
+C10orf105	0.8882	0.01528	0.6553
+TUBA1C	-0.6215	0.01531	0.6553
+ADAMTS9	-0.8947	0.01534	0.6553
+PNMA2	0.4278	0.01524	0.6553
+MAN1C1	-0.5596	0.01579	0.6597
+CDC20	-0.7767	0.01562	0.6597
+PACSIN3	-0.8907	0.01553	0.6597
+PTHLH	-0.9265	0.01572	0.6597
+DAZL	-0.9135	0.01572	0.6597
+SRA1	0.3041	0.01559	0.6597
+ARPC1B	-0.6737	0.0158	0.6597
+IMMP2L	-0.4426	0.01559	0.6597
+ROR2	-0.9148	0.01578	0.6597
+PIEZO1	-0.7733	0.0159	0.6621
+SOCS3	-0.9404	0.01601	0.6634
+LOC150568	0.8026	0.01601	0.6634
+RASL12	-0.8837	0.01609	0.665
+SATL1	0.8447	0.01618	0.6671
+C1orf27	-0.3158	0.01624	0.6679
+TMEM198	0.4547	0.01647	0.6739
+MYOT	-0.928	0.01645	0.6739
+PLAU	-0.8276	0.01655	0.6749
+GPC6	-0.5345	0.01662	0.6749
+COPZ2	-0.9194	0.01661	0.6749
+MTHFR	0.2998	0.01729	0.6753
+PARD3	-0.3704	0.01726	0.6753
+PDIA3	-0.3509	0.01708	0.6753
+TPM1	-0.7177	0.01711	0.6753
+PRC1	-0.5474	0.01718	0.6753
+PLK1	-0.6854	0.01672	0.6753
+PIEZO2	-0.8503	0.01699	0.6753
+ZNF90	-0.7327	0.0169	0.6753
+GALP	0.8155	0.01693	0.6753
+LOC440905	-0.8935	0.01671	0.6753
+RFTN1	-0.8999	0.01677	0.6753
+TMEM196	0.7006	0.01701	0.6753
+NOD1	-0.5152	0.01707	0.6753
+GLI3	-0.8242	0.01696	0.6753
+WBSCR27	-0.9343	0.01718	0.6753
+C7orf34	0.9318	0.01721	0.6753
+FRRS1	-0.8998	0.01774	0.676
+FAM19A3	-0.8923	0.01788	0.676
+CNIH3	-0.4817	0.01784	0.676
+MDK	-0.7156	0.01749	0.676
+GXYLT1	-0.6944	0.01783	0.676
+CTDSP2	-0.5123	0.01765	0.676
+SIX4	-0.8657	0.01784	0.676
+SLCO3A1	0.4415	0.01784	0.676
+PTBP1	-0.4376	0.0178	0.676
+ZNF324	0.3139	0.01754	0.676
+COLEC11	-0.9194	0.01776	0.676
+APOBEC3B	-0.9292	0.01771	0.676
+MAGEF1	0.3826	0.01768	0.676
+SHROOM2	0.5668	0.01763	0.676
+KIAA1217	-0.7442	0.01871	0.69
+ST8SIA1	0.3806	0.01869	0.69
+LOC338758	0.6997	0.01834	0.69
+LOC283731	-0.4064	0.01872	0.69
+LYSMD4	0.4181	0.01859	0.69
+CYP1B1	-0.9248	0.01834	0.69
+PDGFRB	-0.9184	0.01853	0.69
+FKBP5	-0.7347	0.01841	0.69
+AGBL3	0.5843	0.01861	0.69
+MNX1	0.921	0.01864	0.69
+PHKA2	-0.4551	0.01855	0.69
+CCBL2	-0.3365	0.01892	0.6925
+CLIC5	-0.9123	0.01883	0.6925
+WDR67	-0.3832	0.01887	0.6925
+SLC38A5	-0.7194	0.01895	0.6925
+KLF4	-0.8767	0.01907	0.6951
+HSD17B11	-0.6032	0.0192	0.6985
+SLC2A3	-0.5111	0.0193	0.7005
+CSDAP1	-0.7114	0.01946	0.7046
+SBNO2	-0.3452	0.01955	0.7064
+LRRC4C	0.5704	0.01962	0.7074
+ATL3	-0.5278	0.01975	0.7074
+C1S	-0.9056	0.01966	0.7074
+PLAUR	-0.8162	0.01974	0.7074
+LOC256021	0.6774	0.01988	0.709
+EID2B	0.4332	0.01987	0.709
+MTA3	-0.4227	0.02009	0.7151
+BSG	-0.2869	0.02023	0.7167
+LAMP2	-0.2974	0.02022	0.7167
+ATHL1	-0.9069	0.02033	0.7179
+AHNAK	-0.7987	0.02044	0.7179
+IGFBP5	-0.9055	0.02035	0.7179
+MBOAT1	-0.7067	0.02044	0.7179
+EGFR	-0.6912	0.02048	0.7179
+FRAT1	0.4904	0.02073	0.7201
+TBX10	-0.9015	0.02084	0.7201
+KCNA6	0.4245	0.02068	0.7201
+MATN3	-0.8883	0.02079	0.7201
+LTBP1	-0.8212	0.02081	0.7201
+SCARF2	-0.7426	0.02064	0.7201
+BAI3	0.3512	0.02085	0.7201
+LOC654433	0.828	0.02096	0.7226
+GTSE1	-0.5797	0.02106	0.7229
+SCRG1	-0.9048	0.02106	0.7229
+AHCY	-0.5073	0.02111	0.7231
+LRRTM3	0.609	0.02122	0.7239
+MYO1C	-0.7078	0.02121	0.7239
+AKR1E2	0.7441	0.02134	0.7264
+PCDHGB4	-0.8844	0.02142	0.7277
+P2RX4	-0.3807	0.02159	0.7309
+LINC00574	0.7267	0.02161	0.7309
+BPI	-0.8613	0.02171	0.7313
+ATP2B2	0.751	0.02167	0.7313
+CDCA2	-0.6352	0.0218	0.7328
+FGF8	-0.8835	0.02191	0.7338
+FAM198A	-0.8977	0.02192	0.7338
+FMO2	-0.8029	0.0222	0.7401
+LOC642852	0.5471	0.02215	0.7401
+IGF2R	-0.5322	0.02227	0.741
+TIGD3	0.6643	0.02236	0.7426
+GFPT2	-0.6006	0.02241	0.7429
+BCAS2	0.3073	0.02266	0.7431
+IQGAP3	-0.7145	0.02274	0.7431
+ZDHHC20	-0.3828	0.02266	0.7431
+ARID4A	0.2039	0.02278	0.7431
+SPHK1	-0.8455	0.02253	0.7431
+FAM110C	-0.7952	0.02259	0.7431
+PXDN	-0.7352	0.02275	0.7431
+THSD7B	-0.5467	0.02268	0.7431
+PRUNE	0.2438	0.02292	0.7459
+ECE1	-0.7102	0.02311	0.7477
+CECR7	0.8781	0.02308	0.7477
+HTRA3	-0.8843	0.02303	0.7477
+WDR47	0.4054	0.0234	0.7537
+SLITRK5	0.4093	0.02345	0.7537
+AURKB	-0.6811	0.02349	0.7537
+IGFBP4	-0.8858	0.02352	0.7537
+CDC25C	-0.6363	0.02348	0.7537
+GPM6A	0.649	0.02357	0.7538
+BTBD19	-0.7584	0.02376	0.755
+GPR26	0.7615	0.02388	0.755
+SIAH3	0.7351	0.02393	0.755
+PLCB2	-0.8363	0.02385	0.755
+DNM1P35	0.6404	0.02389	0.755
+RRBP1	-0.8115	0.0238	0.755
+ACOT8	0.3293	0.02375	0.755
+OLFML2B	-0.8708	0.02414	0.7572
+TROAP	-0.7143	0.02411	0.7572
+WIPI1	-0.6362	0.02411	0.7572
+VOPP1	0.2574	0.02422	0.7584
+HES1	-0.5633	0.02436	0.7611
+FIBIN	-0.8826	0.02444	0.7624
+KDELC2	-0.8298	0.02449	0.7625
+ERRFI1	-0.5181	0.02486	0.767
+ZNF26	0.2525	0.0249	0.767
+RAB20	-0.7225	0.02495	0.767
+CEP112	-0.5528	0.02496	0.767
+PDYN	0.8461	0.02487	0.767
+SEL1L3	-0.794	0.0249	0.767
+CENPE	-0.581	0.02474	0.767
+LOC100505695	-0.8418	0.02506	0.7684
+ST3GAL6	0.3335	0.02515	0.7698
+PPPDE1	-0.3884	0.02552	0.7705
+CYFIP1	-0.4708	0.02549	0.7705
+SPAG5	-0.6341	0.02525	0.7705
+FSTL3	-0.3936	0.02544	0.7705
+DKKL1	-0.5961	0.02555	0.7705
+PLA2R1	-0.8383	0.02533	0.7705
+SH3RF2	-0.8594	0.02543	0.7705
+NEDD9	-0.5615	0.02537	0.7705
+LOC400940	0.7406	0.02573	0.7737
+NPR2	-0.6064	0.02575	0.7737
+CKS1B	-0.6537	0.02617	0.778
+RNASEL	0.8586	0.02631	0.778
+KIAA1462	-0.8624	0.02641	0.778
+C10orf2	0.3805	0.02618	0.778
+PRKCDBP	-0.8186	0.02624	0.778
+ZNF564	0.3025	0.02598	0.778
+LOC100506421	0.6526	0.02601	0.778
+SNED1	-0.8004	0.02611	0.778
+SGMS2	-0.8683	0.02638	0.778
+TMEM151B	0.4716	0.02635	0.778
+LOC100507341	0.6623	0.02622	0.778
+KIF2C	-0.6374	0.02666	0.7837
+PRX	-0.6445	0.02676	0.7854
+LOXL4	-0.8597	0.02686	0.7864
+STXBP6	0.6668	0.02689	0.7864
+FAM13A	-0.4611	0.02712	0.7917
+IFITM10	0.6685	0.02744	0.7925
+CBFB	-0.3576	0.02735	0.7925
+DKFZp566F0947	-0.8205	0.02736	0.7925
+MAGI2	0.4314	0.02741	0.7925
+NIPAL2	-0.7441	0.0274	0.7925
+GPRASP2	0.4453	0.02732	0.7925
+DPH3P1	-0.5664	0.02774	0.7999
+C1orf54	-0.5484	0.02801	0.8025
+LIG4	0.3168	0.02811	0.8025
+GREM1	-0.8574	0.02807	0.8025
+TPM4	-0.6659	0.028	0.8025
+OSBPL10	-0.7943	0.02789	0.8025
+HPS3	-0.3542	0.02812	0.8025
+ANP32B	-0.4906	0.02825	0.8047
+FAM176B	-0.6818	0.02966	0.8067
+HPCAL4	0.5034	0.02927	0.8067
+LEPRE1	-0.7027	0.03137	0.8067
+MCOLN3	-0.7816	0.02861	0.8067
+GBP3	-0.8426	0.03082	0.8067
+SELENBP1	-0.7428	0.03013	0.8067
+LMNA	-0.499	0.03161	0.8067
+KCNJ9	0.7358	0.02904	0.8067
+CENPL	-0.3831	0.02874	0.8067
+KIF14	-0.6281	0.0329	0.8067
+EIF2D	-0.4348	0.02953	0.8067
+CAPN2	-0.3726	0.02973	0.8067
+RGR	0.8449	0.03118	0.8067
+EFCAB4A	-0.6655	0.03031	0.8067
+TPP1	-0.3513	0.03121	0.8067
+MICAL2	-0.85	0.02966	0.8067
+C11orf94	0.8245	0.03271	0.8067
+NADSYN1	-0.3401	0.03253	0.8067
+FOXM1	-0.5518	0.02937	0.8067
+SLC38A1	0.3146	0.03036	0.8067
+ANKS1B	0.6226	0.03231	0.8067
+GJB6	-0.7271	0.03074	0.8067
+ANG	-0.7201	0.02984	0.8067
+DLGAP5	-0.6065	0.03271	0.8067
+FAM161B	0.3957	0.02968	0.8067
+SERPINA5	-0.831	0.03008	0.8067
+RASGRP1	-0.4108	0.02946	0.8067
+THBS1	-0.85	0.0302	0.8067
+ST8SIA2	0.4492	0.03147	0.8067
+RPS2	-0.4238	0.03074	0.8067
+ITPRIPL2	-0.854	0.02869	0.8067
+NFATC3	-0.4057	0.02928	0.8067
+PLD2	-0.669	0.03252	0.8067
+SMCR7	0.3445	0.02996	0.8067
+SMARCD2	-0.6611	0.03159	0.8067
+TUBB6	-0.7194	0.0311	0.8067
+DSG2	-0.6812	0.03226	0.8067
+ACAA2	-0.446	0.0318	0.8067
+GADD45B	-0.8334	0.0328	0.8067
+CELF5	0.4393	0.03193	0.8067
+TMEM221	-0.7671	0.03202	0.8067
+WDR62	-0.5769	0.02965	0.8067
+ZNF570	0.2708	0.02949	0.8067
+SPRED3	0.6054	0.03154	0.8067
+RPL13A	-0.6422	0.03157	0.8067
+BCL2L12	-0.4817	0.02883	0.8067
+CENPA	-0.6156	0.03213	0.8067
+MTHFD2	-0.7685	0.03077	0.8067
+FAM176A	-0.8313	0.03045	0.8067
+GCFC2	-0.344	0.02982	0.8067
+CAPG	-0.8383	0.0296	0.8067
+EDAR	-0.846	0.03099	0.8067
+BUB1	-0.5945	0.02946	0.8067
+ZRANB3	-0.5034	0.03047	0.8067
+SLC4A10	0.725	0.03287	0.8067
+WIPF1	-0.555	0.02846	0.8067
+CCDC141	-0.8347	0.02951	0.8067
+CCDC150	-0.5535	0.03183	0.8067
+ASXL1	-0.4027	0.03086	0.8067
+SS18L1	0.3675	0.03085	0.8067
+C22orf29	0.2474	0.03243	0.8067
+SMCR7L	0.1929	0.03016	0.8067
+GRIP2	0.8047	0.03072	0.8067
+GPR62	0.808	0.03283	0.8067
+MITF	-0.7604	0.03019	0.8067
+FDCSP	-0.8326	0.03137	0.8067
+ANXA2P1	-0.6149	0.0322	0.8067
+LHFPL2	-0.7202	0.03111	0.8067
+ERAP1	-0.4938	0.03164	0.8067
+MXD3	-0.6781	0.02998	0.8067
+TEAD3	-0.7435	0.02893	0.8067
+SP4	0.3326	0.03284	0.8067
+TRIL	-0.7788	0.0308	0.8067
+STK17A	-0.3401	0.02899	0.8067
+RARRES2	-0.844	0.02997	0.8067
+CHMP7	0.283	0.03105	0.8067
+ZNF703	-0.6856	0.03162	0.8067
+ST18	0.5283	0.03123	0.8067
+LOC100132891	-0.7824	0.03111	0.8067
+C8orf84	-0.7652	0.03183	0.8067
+ZFHX4	0.4288	0.03044	0.8067
+GDF6	-0.8041	0.03241	0.8067
+RANBP6	0.3012	0.03171	0.8067
+FAM189A2	-0.8114	0.0328	0.8067
+TNC	-0.8197	0.03225	0.8067
+ZBTB6	0.3295	0.02968	0.8067
+RPL12	-0.5342	0.02943	0.8067
+GBGT1	-0.8343	0.03067	0.8067
+ARHGAP6	-0.8167	0.03244	0.8067
+SHROOM4	-0.645	0.03263	0.8067
+HDX	0.4208	0.03269	0.8067
+COL4A5	-0.7708	0.03259	0.8067
+GAB3	-0.7788	0.03107	0.8067
+B3GALNT2	-0.5213	0.03322	0.809
+ZNF142	0.2381	0.03314	0.809
+HEXB	-0.4081	0.03323	0.809
+PPP1R3G	-0.8344	0.03314	0.809
+MDFIC	-0.6575	0.03324	0.809
+RXFP3	0.832	0.03336	0.8098
+PTTG3P	-0.6051	0.03333	0.8098
+C1orf133	-0.7152	0.03375	0.8176
+TP53I13	-0.422	0.03379	0.8176
+SLC44A3	-0.7081	0.03438	0.8264
+C1orf115	-0.6315	0.03446	0.8264
+ANO4	-0.7486	0.03437	0.8264
+FNIP2	0.2913	0.03444	0.8264
+CRHBP	-0.8231	0.03437	0.8264
+KIAA0368	-0.3228	0.0344	0.8264
+PLCE1	-0.7467	0.03491	0.8277
+PARPBP	-0.5436	0.0348	0.8277
+FRMD6	-0.7527	0.03488	0.8277
+LIN7B	0.5171	0.03464	0.8277
+COL4A3BP	-0.5851	0.03462	0.8277
+SCML4	0.7487	0.03473	0.8277
+ZNF815	0.3814	0.03489	0.8277
+DIRAS2	0.4271	0.03474	0.8277
+SULT1A1	-0.7929	0.03504	0.8292
+ADAMTS9-AS2	-0.7074	0.03508	0.8292
+CHTOP	0.2474	0.03521	0.8311
+DKK2	-0.8042	0.03534	0.8331
+HIST1H1D	-0.8219	0.03541	0.8335
+CDK1	-0.5524	0.03609	0.8345
+SHISA2	-0.8216	0.03606	0.8345
+GJD2	0.6358	0.03608	0.8345
+CCNB2	-0.6054	0.0358	0.8345
+OMG	0.805	0.03565	0.8345
+MYL4	-0.7755	0.03625	0.8345
+LOC100131096	-0.7581	0.03632	0.8345
+HSPB6	-0.8208	0.03557	0.8345
+STEAP3	-0.5503	0.0359	0.8345
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+APOL4	-0.8187	0.03588	0.8345
+BAP1	0.1786	0.03614	0.8345
+PHLDB2	-0.8077	0.03626	0.8345
+NAP1L5	0.4839	0.03554	0.8345
+CFI	-0.7104	0.0361	0.8345
+SORBS3	-0.6631	0.03587	0.8345
+TOP1MT	-0.4407	0.03585	0.8345
+OPLAH	-0.4763	0.03653	0.8383
+ASAP3	-0.2714	0.03787	0.8394
+TSG101	0.2283	0.03752	0.8394
+CPT1A	-0.3581	0.0378	0.8394
+GALNT6	-0.7937	0.03784	0.8394
+KCNK10	0.5243	0.03782	0.8394
+ISL2	0.8166	0.03724	0.8394
+GOLGA6L10	0.8026	0.03693	0.8394
+TMEM100	-0.8097	0.03759	0.8394
+TBC1D16	0.2885	0.03692	0.8394
+JUNB	-0.5495	0.03735	0.8394
+ZNF614	0.2666	0.03762	0.8394
+ZNF600	-0.742	0.0372	0.8394
+TCF7L1	-0.5031	0.03767	0.8394
+ACOX2	-0.7993	0.03678	0.8394
+FAM107A	0.8057	0.03704	0.8394
+FGFBP2	-0.7944	0.03791	0.8394
+LOC644100	0.8085	0.03748	0.8394
+CPEB4	0.477	0.03704	0.8394
+GUCA1A	0.4614	0.03744	0.8394
+CALD1	-0.7359	0.03704	0.8394
+EPHB6	0.6366	0.03748	0.8394
+PENK	-0.8034	0.03669	0.8394
+TMEM74	0.5734	0.03704	0.8394
+RPS6	-0.5392	0.03785	0.8394
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+GRIP1	0.4312	0.03808	0.8408
+PDE1A	0.6831	0.03824	0.8421
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+C14orf39	-0.7682	0.03839	0.8434
+SCPEP1	-0.6581	0.0384	0.8434
+CTNNA3	-0.8021	0.03904	0.8447
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+HAUS4	-0.5229	0.03918	0.8447
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+RND1	0.5434	0.0393	0.8462
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+TMEM121	0.7264	0.03957	0.8475
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+LAYN	-0.8004	0.04001	0.8493
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+BK250D10.8	0.3937	0.05558	0.9136
+BMP8A	-0.7009	0.05622	0.9151
+PGAP2	-0.3165	0.05633	0.9151
+SWAP70	-0.4554	0.0566	0.9151
+ADAMTS15	-0.6933	0.05643	0.9151
+ZNF764	0.3128	0.0558	0.9151
+ZNF232	0.2936	0.05621	0.9151
+KIF19	0.5423	0.05632	0.9151
+DAPK3	0.1446	0.05616	0.9151
+RAB11FIP5	-0.5362	0.05662	0.9151
+PIGT	-0.211	0.05644	0.9151
+APOL3	-0.7264	0.05642	0.9151
+EDEM1	-0.4362	0.05601	0.9151
+FAM19A1	0.7263	0.05646	0.9151
+CHST2	-0.7082	0.05652	0.9151
+PCDHB6	0.7317	0.05617	0.9151
+STL	-0.5892	0.05589	0.9151
+COL27A1	-0.6396	0.05586	0.9151
+KBTBD6	0.2566	0.05675	0.9163
+MTRF1L	0.3595	0.05681	0.9165
+MTMR11	-0.7208	0.05693	0.9174
+HEPHL1	-0.7323	0.05731	0.9174
+ORAI1	-0.5665	0.05732	0.9174
+ZCCHC14	0.2114	0.05708	0.9174
+PROS1	-0.5312	0.05722	0.9174
+SPRY1	-0.6335	0.05712	0.9174
+GNE	0.2803	0.05701	0.9174
+COL4A6	-0.6533	0.05724	0.9174
+NFIC	-0.6436	0.05747	0.9176
+ZNF791	0.2921	0.05742	0.9176
+SNORA51	-0.7026	0.0575	0.9176
+MYOZ3	-0.6044	0.05764	0.918
+POLA1	-0.5954	0.05762	0.918
+HADHA	-0.3	0.05792	0.9207
+DOCK3	0.4706	0.05788	0.9207
+LMO3	0.5316	0.05797	0.9207
+NACAD	0.4385	0.05805	0.9211
+CCNB1	-0.5201	0.05812	0.9213
+SERPIND1	-0.734	0.05823	0.9221
+STK24	-0.2142	0.05842	0.9242
+PHF13	-0.298	0.06011	0.9248
+H6PD	-0.6251	0.05921	0.9248
+NBPF3	-0.3613	0.06067	0.9248
+CITED4	0.5124	0.05994	0.9248
+KIAA0494	-0.2546	0.06016	0.9248
+CYP2J2	-0.7292	0.0595	0.9248
+CCDC18	-0.3993	0.0611	0.9248
+DPYD	-0.6279	0.05986	0.9248
+ZNF124	0.4382	0.06107	0.9248
+NUDT9P1	-0.736	0.06061	0.9248
+NOLC1	0.1861	0.06088	0.9248
+TMEM151A	0.6092	0.05888	0.9248
+LOC283440	0.7396	0.05886	0.9248
+ANKRD13A	-0.2697	0.05956	0.9248
+ANGEL1	0.4337	0.05894	0.9248
+GOLGA8A	-0.5509	0.05949	0.9248
+CEP152	-0.5326	0.06011	0.9248
+CSK	0.1848	0.06088	0.9248
+NARFL	0.1938	0.05898	0.9248
+CLEC19A	-0.6688	0.05939	0.9248
+LPCAT2	-0.6738	0.0593	0.9248
+PRSS54	-0.6714	0.06105	0.9248
+CDRT15P1	-0.7006	0.06078	0.9248
+USP22	0.2237	0.06035	0.9248
+GFAP	-0.714	0.0604	0.9248
+TWSG1	-0.4535	0.06073	0.9248
+FAHD2B	-0.458	0.05948	0.9248
+STAC	-0.42	0.0604	0.9248
+POC1A	-0.4775	0.06046	0.9248
+PLCXD2	0.4898	0.05945	0.9248
+PLXND1	-0.6599	0.05919	0.9248
+CCNA2	-0.5693	0.06073	0.9248
+LOC728613	0.6618	0.06083	0.9248
+CMBL	-0.3903	0.06015	0.9248
+CDH6	-0.4624	0.05947	0.9248
+KIF3A	0.3681	0.05868	0.9248
+SEPT8	-0.3378	0.05929	0.9248
+CYSTM1	-0.2853	0.05914	0.9248
+PCDHB8	0.7297	0.06054	0.9248
+NPM1	-0.4934	0.06014	0.9248
+NKX2-5	-0.6424	0.06051	0.9248
+KLHL31	-0.6516	0.0607	0.9248
+TTK	-0.5141	0.06104	0.9248
+FUCA2	-0.3714	0.05959	0.9248
+ADAM22	0.2472	0.06023	0.9248
+TMEM176B	-0.7388	0.05944	0.9248
+PEBP4	0.7109	0.06087	0.9248
+TAS1R3	0.5557	0.06516	0.9251
+LOC388588	-0.626	0.06494	0.9251
+AGBL4	0.6518	0.06785	0.9251
+LMO4	-0.4769	0.0639	0.9251
+SLC25A24	-0.592	0.06454	0.9251
+PSRC1	-0.5136	0.06296	0.9251
+MOV10	-0.5781	0.06249	0.9251
+NBPF16	-0.6464	0.06794	0.9251
+NR1I3	0.644	0.06458	0.9251
+MYOC	0.6636	0.06405	0.9251
+LEMD1	0.4305	0.06631	0.9251
+NEK2	-0.6711	0.06807	0.9251
+MAP1LC3C	-0.706	0.06706	0.9251
+ITGB1	-0.4866	0.06647	0.9251
+ZNF25	0.2887	0.06377	0.9251
+REEP3	-0.4063	0.06811	0.9251
+LOC100288974	-0.7105	0.06576	0.9251
+ANXA11	-0.7142	0.0656	0.9251
+BLNK	-0.7268	0.063	0.9251
+PKD2L1	0.6622	0.06545	0.9251
+C10orf82	0.5933	0.0636	0.9251
+ZRANB1	0.277	0.06565	0.9251
+RHOG	-0.4954	0.06342	0.9251
+C12orf60	0.5324	0.06702	0.9251
+FMNL3	-0.4149	0.067	0.9251
+LOC100507250	0.5542	0.06792	0.9251
+PPFIA2	0.4545	0.0657	0.9251
+BTG1	0.3694	0.06776	0.9251
+ACTR6	0.2759	0.06305	0.9251
+ELF1	-0.4009	0.06604	0.9251
+ABCC4	-0.6553	0.06527	0.9251
+MBNL2	-0.3685	0.06499	0.9251
+GRTP1	-0.4961	0.06196	0.9251
+NKX2-1	0.7098	0.06567	0.9251
+FBLN5	-0.6834	0.06507	0.9251
+SLC24A4	0.7237	0.06347	0.9251
+RIN3	-0.7138	0.06356	0.9251
+GSC	-0.677	0.06558	0.9251
+WHAMMP3	-0.6576	0.06473	0.9251
+SHC4	0.5361	0.06739	0.9251
+FLJ10038	0.3791	0.06352	0.9251
+PPIB	-0.3257	0.06689	0.9251
+SKOR1	0.7045	0.06272	0.9251
+SEC11A	-0.3392	0.06784	0.9251
+MESP2	-0.6863	0.06485	0.9251
+TTC23	-0.3564	0.06667	0.9251
+IRX5	-0.7205	0.06582	0.9251
+PARD6A	0.4626	0.06806	0.9251
+LOC100506083	0.4945	0.06473	0.9251
+AP1G1	0.1424	0.06301	0.9251
+SLC43A2	0.3494	0.06221	0.9251
+CALCOCO2	-0.3496	0.06389	0.9251
+SEPT9	-0.4146	0.06707	0.9251
+NARF	0.2003	0.06722	0.9251
+SLC14A2	0.7223	0.0623	0.9251
+SGTA	0.2295	0.06681	0.9251
+STAP2	-0.4388	0.06778	0.9251
+CACNA1A	0.6005	0.0633	0.9251
+PBX4	-0.5926	0.06672	0.9251
+ZNF30	0.2213	0.06755	0.9251
+SAMD4B	-0.1824	0.06461	0.9251
+TGFB1	-0.6255	0.06443	0.9251
+SLC8A2	0.5135	0.06325	0.9251
+FLT3LG	-0.692	0.0649	0.9251
+TMEM214	-0.496	0.06786	0.9251
+PLB1	-0.7173	0.06319	0.9251
+EML4	-0.4048	0.06662	0.9251
+TEKT4	0.701	0.06517	0.9251
+FAHD2A	-0.2582	0.06363	0.9251
+LIMS1	-0.5014	0.06794	0.9251
+POTEF	-0.7024	0.06758	0.9251
+NCKAP5	-0.3493	0.06549	0.9251
+SERPINE2	-0.3999	0.06232	0.9251
+NYAP2	0.6993	0.06519	0.9251
+ZNF217	-0.5587	0.06492	0.9251
+CBLN4	0.5841	0.06282	0.9251
+USP25	-0.3405	0.06659	0.9251
+LHFPL4	0.5292	0.06225	0.9251
+VGLL4	-0.3355	0.06504	0.9251
+RBMS3	-0.6397	0.06258	0.9251
+ZNF167	0.4354	0.06685	0.9251
+SEMA3B	-0.6083	0.0665	0.9251
+ROBO2	0.3634	0.06146	0.9251
+NIT2	-0.5819	0.06183	0.9251
+ABI3BP	-0.7291	0.06193	0.9251
+DZIP3	0.3206	0.06691	0.9251
+PVRL3-AS1	0.6451	0.06801	0.9251
+TAGLN3	0.4329	0.06554	0.9251
+BOC	-0.6256	0.06355	0.9251
+GYG1	-0.3685	0.06421	0.9251
+NAALADL2	-0.6888	0.0651	0.9251
+LEPREL1	-0.7291	0.0615	0.9251
+PRKG2	-0.6991	0.06468	0.9251
+CYP4V2	0.5012	0.06519	0.9251
+C6	-0.6988	0.06235	0.9251
+ISOC1	-0.5486	0.0642	0.9251
+PCDHB10	0.3254	0.06221	0.9251
+ANXA6	-0.6452	0.06552	0.9251
+KIF4B	-0.5101	0.06523	0.9251
+PRR7	0.1904	0.06493	0.9251
+LOC729678	0.6278	0.06551	0.9251
+HIST1H3J	-0.6119	0.06763	0.9251
+ZBTB22	0.2669	0.06404	0.9251
+KIFC1	-0.549	0.06264	0.9251
+TBP	0.2407	0.0661	0.9251
+PMS2CL	0.3408	0.06648	0.9251
+FKBP14	-0.6002	0.06604	0.9251
+FKBP9	-0.4174	0.06186	0.9251
+GRM3	0.6129	0.06304	0.9251
+EPHB4	-0.6453	0.06787	0.9251
+LRRN3	0.5473	0.068	0.9251
+KIAA1147	0.257	0.06708	0.9251
+FAM115A	0.2185	0.06468	0.9251
+PDIA4	-0.4169	0.06375	0.9251
+ZNF775	0.2417	0.06198	0.9251
+FAM110B	0.2576	0.0615	0.9251
+DMRT3	0.7178	0.06674	0.9251
+CDKN2B	-0.7039	0.06592	0.9251
+TSTD2	0.2954	0.06597	0.9251
+PTGES	-0.7016	0.06267	0.9251
+FIBCD1	-0.6829	0.06516	0.9251
+STARD8	-0.7074	0.06244	0.9251
+KLHL4	-0.6903	0.0657	0.9251
+SH2D1A	-0.6782	0.06569	0.9251
+HLX	-0.6728	0.06837	0.927
+FOSB	-0.6318	0.06832	0.927
+AKR1C3	-0.7137	0.06854	0.9278
+NFE2L2	-0.3512	0.06853	0.9278
+TRIP10	-0.5324	0.06872	0.9279
+ZNF14	0.3806	0.06869	0.9279
+DAB2	-0.5142	0.06862	0.9279
+CCNE1	-0.4662	0.06905	0.9309
+CRTAP	-0.5294	0.06906	0.9309
+MYBPHL	-0.6574	0.06967	0.9317
+RAB13	-0.5093	0.07021	0.9317
+IFITM2	-0.7098	0.06986	0.9317
+WEE1	-0.349	0.07071	0.9317
+LIN7C	0.3113	0.07001	0.9317
+NEAT1	-0.5604	0.06935	0.9317
+PRICKLE1	-0.6021	0.06958	0.9317
+TNFRSF12A	-0.525	0.07083	0.9317
+ROGDI	0.3456	0.06977	0.9317
+CLEC16A	0.197	0.06923	0.9317
+TRADD	-0.6894	0.0708	0.9317
+ATXN7L3	0.2479	0.07036	0.9317
+COIL	0.2361	0.06995	0.9317
+SPAST	0.3323	0.07065	0.9317
+RQCD1	0.2386	0.07059	0.9317
+HDLBP	-0.3856	0.07093	0.9317
+ZNF502	0.7101	0.06932	0.9317
+LRRC58	-0.3642	0.07076	0.9317
+C4orf48	0.2925	0.07013	0.9317
+HMX1	-0.702	0.07093	0.9317
+SLC39A8	-0.3564	0.06976	0.9317
+PARP8	0.26	0.07093	0.9317
+AGXT2L2	-0.4154	0.07086	0.9317
+HIST1H4K	-0.6587	0.07053	0.9317
+MDFI	-0.4686	0.0692	0.9317
+TFEB	-0.5835	0.07031	0.9317
+SOBP	0.2902	0.0707	0.9317
+EPM2A	0.3081	0.0706	0.9317
+RASEF	-0.7099	0.07028	0.9317
+TOR2A	0.1958	0.07037	0.9317
+EFNB1	-0.4579	0.07022	0.9317
+IRS4	-0.6417	0.07016	0.9317
+FMNL1	0.5174	0.07107	0.9322
+CABLES2	0.1954	0.07108	0.9322
+PALMD	-0.7062	0.07154	0.933
+ARHGAP30	0.4733	0.07142	0.933
+SLC6A12	-0.6354	0.0716	0.933
+FBXL8	-0.669	0.0716	0.933
+MPP4	-0.6609	0.07149	0.933
+FAM169A	0.2892	0.07155	0.933
+POPDC3	-0.6543	0.07148	0.933
+PRKDC	-0.3408	0.07144	0.933
+MTCP1NB	-0.3672	0.07166	0.9331
+KLHL35	0.547	0.07195	0.9361
+LOC388630	-0.6851	0.07216	0.9373
+TERF2	0.2403	0.07216	0.9373
+PDIK1L	0.3225	0.07438	0.9393
+CDKN2C	-0.5881	0.07417	0.9393
+STAM	0.2146	0.07258	0.9393
+CEP55	-0.5626	0.07374	0.9393
+OAT	-0.3282	0.07472	0.9393
+DPYSL4	0.3403	0.07368	0.9393
+INCENP	-0.4533	0.07294	0.9393
+FLJ39051	0.4429	0.07465	0.9393
+TNFRSF1A	-0.5017	0.07441	0.9393
+EMP1	-0.6983	0.07371	0.9393
+LRRK2	-0.638	0.07436	0.9393
+HMGA2	-0.6418	0.07437	0.9393
+PAWR	-0.4633	0.07481	0.9393
+KDELC1	-0.4797	0.07463	0.9393
+STOML1	0.44	0.073	0.9393
+CPLX3	0.5793	0.07442	0.9393
+IQGAP1	-0.5202	0.07443	0.9393
+UNC45A	-0.399	0.07369	0.9393
+QPRT	-0.459	0.07395	0.9393
+FHOD1	-0.5817	0.07342	0.9393
+PMFBP1	-0.6728	0.07513	0.9393
+VPS53	0.2412	0.07388	0.9393
+GSG2	-0.5565	0.07526	0.9393
+DNAH2	0.5147	0.0737	0.9393
+MRM1	0.4208	0.07515	0.9393
+MPP2	0.354	0.07332	0.9393
+ITGB4	-0.6953	0.07405	0.9393
+CCDC68	-0.696	0.07529	0.9393
+SALL3	0.49	0.07403	0.9393
+TMC4	-0.5552	0.0751	0.9393
+ZNF329	0.2676	0.07305	0.9393
+ZNF324B	0.4072	0.07329	0.9393
+MAT2A	0.3537	0.0727	0.9393
+RND3	0.4659	0.07447	0.9393
+IL5RA	0.6958	0.07526	0.9393
+TUSC2	0.3129	0.07499	0.9393
+TACC3	-0.4554	0.07503	0.9393
+RGS12	0.2794	0.07467	0.9393
+KLHL8	0.2803	0.07494	0.9393
+CXXC4	0.3722	0.07323	0.9393
+RAB33B	-0.3195	0.07345	0.9393
+LRP2BP	0.5095	0.0735	0.9393
+RIOK1	0.2755	0.07471	0.9393
+GUSB	-0.289	0.07272	0.9393
+WNT16	-0.6902	0.07499	0.9393
+MTMR9	0.4022	0.07321	0.9393
+RB1CC1	0.1851	0.07324	0.9393
+LOC100130301	-0.6884	0.07526	0.9393
+ZHX2	-0.1906	0.07262	0.9393
+C8orf31	0.662	0.07311	0.9393
+PTPLAD2	-0.6807	0.07516	0.9393
+ANGPTL2	-0.6812	0.0727	0.9393
+XKR9	0.6838	0.07538	0.9397
+NPM3	-0.43	0.07558	0.9414
+NGF	-0.6824	0.07589	0.9417
+WDR37	0.2218	0.076	0.9417
+NPFFR1	0.6156	0.07579	0.9417
+GIPC3	-0.696	0.07581	0.9417
+ERBB4	0.5386	0.07567	0.9417
+GHR	-0.6939	0.07599	0.9417
+VWDE	-0.6838	0.07595	0.9417
+RPS4X	-0.5797	0.0761	0.9423
+CDK2AP2	-0.3551	0.07631	0.9432
+LOC146336	0.693	0.07658	0.9432
+UBE2C	-0.6278	0.07624	0.9432
+C22orf39	0.2448	0.07654	0.9432
+MFSD7	-0.6817	0.07645	0.9432
+CANX	-0.2312	0.07664	0.9432
+VIPR2	0.6908	0.07663	0.9432
+PPP1R3B	-0.5682	0.07643	0.9432
+TMEM229B	0.5479	0.0767	0.9433
+PCDH17	0.2916	0.07683	0.9434
+HOXA10	-0.6931	0.0768	0.9434
+SYT12	0.5719	0.077	0.9434
+FLJ44054	-0.6519	0.07698	0.9434
+BASP1	0.4201	0.07695	0.9434
+NCAPH2	0.2371	0.07719	0.9445
+PLA1A	-0.5791	0.07721	0.9445
+EGFLAM	-0.6643	0.07726	0.9445
+CD151	-0.3897	0.0774	0.9449
+STX11	-0.677	0.07738	0.9449
+APRT	-0.3698	0.07756	0.9456
+PTPN2	-0.342	0.07763	0.9456
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+ARRDC2	-0.5913	0.0778	0.9469
+POLD4	-0.613	0.07788	0.9471
+LDLRAP1	-0.6823	0.07828	0.9475
+SYDE2	-0.558	0.07807	0.9475
+TP53BP2	-0.3194	0.07848	0.9475
+ADAM12	-0.5572	0.07815	0.9475
+GAL3ST2	0.6873	0.07821	0.9475
+CTNND2	0.2648	0.07819	0.9475
+TSPAN13	0.4076	0.0783	0.9475
+RPS2P32	0.6489	0.0784	0.9475
+SLC26A7	-0.6902	0.07843	0.9475
+C9orf7	0.2083	0.07848	0.9475
+CDCA8	-0.5135	0.0788	0.9479
+MKNK1	-0.2483	0.07956	0.9479
+TOMM40L	0.3821	0.0791	0.9479
+PTGS2	-0.6878	0.07897	0.9479
+DNAJC1	-0.4755	0.07904	0.9479
+TLL2	0.5684	0.07932	0.9479
+PSD	0.5206	0.07953	0.9479
+LIMA1	-0.4947	0.07919	0.9479
+RBMS2	-0.4759	0.07932	0.9479
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+EEF1DP3	0.6545	0.07897	0.9479
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+BTN1A1	-0.2202	0.5705	0.9994
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+ABT1	0.123	0.5001	0.9994
+ZNF322	0.157	0.3812	0.9994
+GUSBP2	-0.2328	0.5528	0.9994
+LINC00240	-0.1788	0.6388	0.9994
+LOC100270746	-0.05033	0.8828	0.9994
+HIST1H2AG	-0.5393	0.1081	0.9994
+HIST1H2BK	-0.03837	0.8604	0.9994
+HIST1H2AH	-0.2761	0.4764	0.9994
+ZNF204P	-0.2542	0.4213	0.9994
+ZNF184	-0.1138	0.4413	0.9994
+LOC100507173	-0.1493	0.6236	0.9994
+HIST1H2BL	-0.04932	0.8964	0.9994
+HIST1H2AI	0.2051	0.6003	0.9994
+HIST1H3H	-0.3543	0.3615	0.9994
+HIST1H2BM	-0.4948	0.185	0.9994
+HIST1H2BN	0.155	0.6876	0.9994
+HIST1H2AL	-0.548	0.1572	0.9994
+HIST1H1B	-0.4754	0.189	0.9994
+HIST1H3I	-0.1796	0.6463	0.9994
+HIST1H2BO	-0.5505	0.143	0.9994
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+ZSCAN16	0.3326	0.165	0.9994
+ZNF192	-0.04322	0.8754	0.9994
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+ZNF193	0.09803	0.6999	0.9994
+ZKSCAN4	0.1753	0.3942	0.9994
+ZNF187	0.1084	0.5508	0.9994
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+ZNF323	0.1397	0.6054	0.9994
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+LOC401242	0.01635	0.9664	0.9994
+TRIM27	0.0423	0.714	0.9994
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+HLA-F	-0.507	0.1877	0.9994
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+HLA-G	-0.5746	0.1427	0.9994
+HLA-H	-0.5919	0.1214	0.9994
+HCG4B	-0.3472	0.3251	0.9994
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+TRIM26	0.08034	0.7298	0.9994
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+APOM	0.06867	0.7999	0.9994
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+SNORD48	-0.2153	0.576	0.9994
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+ANAPC16	-0.0007184	0.996	0.9996
+CHCHD1	-0.0003005	0.9983	0.9996
+GHITM	0.001448	0.9937	0.9996
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+TAF5	0.002798	0.9922	0.9996
+SORCS1	0.0009783	0.997	0.9996
+TCERG1L	0.001615	0.9952	0.9996
+NKX6-2	-0.0008079	0.9984	0.9996
+HBBP1	-0.002008	0.9939	0.9996
+TRIM66	-0.001007	0.9977	0.9996
+DAK	0.001217	0.9964	0.9996
+PDE2A	0.003856	0.9917	0.9996
+USP35	-0.001857	0.9946	0.9996
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+ENDOD1	0.002419	0.9942	0.9996
+LOC100507424	-0.00107	0.9977	0.9996
+NTF3	-0.001251	0.9974	0.9996
+HTR7P1	0.0009986	0.998	0.9996
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+MCRS1	-0.001476	0.993	0.9996
+LOC100240734	0.002675	0.9945	0.9996
+TSPAN31	0.0008547	0.9961	0.9996
+MED13L	0.00217	0.9934	0.9996
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+RAB2B	0.001374	0.995	0.9996
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+EFCAB11	0.0008383	0.9982	0.9996
+SLC25A47	0.002553	0.9946	0.9996
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+MGA	0.001088	0.9956	0.9996
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+COG7	-0.0007377	0.9961	0.9996
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+TMPRSS15	-0.001422	0.9971	0.9996
+SH3BGR	-0.0006994	0.9974	0.9996
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+MTFP1	-0.0007746	0.9976	0.9996
+EP300	-0.0003846	0.9982	0.9996
+PACSIN2	-0.001144	0.9917	0.9996
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+SENP5	-0.0003959	0.9986	0.9996
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+LRRC66	-0.0006605	0.9985	0.9996
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+TIGD6	0.002251	0.9943	0.9996
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+LOC100507194	-0.004099	0.9916	0.9996
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+CCM2	-0.000938	0.9955	0.9996
+WBSCR16	0.001843	0.9928	0.9996
+LOC155060	-0.003811	0.9916	0.9996
+C8orf42	0.001161	0.9975	0.9996
+CSGALNACT1	-0.001458	0.9967	0.9996
+PPAPDC1B	0.0008906	0.9974	0.9996
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+ISCU	0.0001513	0.9992	0.9998
+CUEDC1	-0.0002373	0.999	0.9998
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+ZNF346	0.0001664	0.999	0.9998
+LOC100128750	-0.0004801	0.999	0.9998
+USP11	-0.0003655	0.9991	0.9998
+N4BP1	-0.0001139	0.9994	0.9998
+CIRBP-AS1	0.0002081	0.9995	0.9998
+PKLR	-0.0001906	0.9996	0.9999
+OBFC1	-4.637e-05	0.9998	0.9999
+FKBP8	-5.51e-05	0.9997	0.9999
+LRMP	-3.651e-05	0.9999	1
+OXSM	8.828e-06	1	1
\ No newline at end of file