diff lifelines_tool/README.md @ 2:dd5e65893cb8 draft default tip

add survival and collapsed life table outputs suggested by Wolfgang
author fubar
date Thu, 10 Aug 2023 22:52:45 +0000
parents 232b874046a7
children
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--- a/lifelines_tool/README.md	Thu Aug 10 07:15:22 2023 +0000
+++ b/lifelines_tool/README.md	Thu Aug 10 22:52:45 2023 +0000
@@ -1,28 +1,40 @@
 # lifelines_tool - lifelines statistical package wrapped as a Galaxy tool.
 
-## Galaxy tool to run failure time models using lifelines
+A Galaxy tool for right censored failure time data.
+
+Provides Kaplan-Meier plots with confidence intervals, and optional Cox proportional hazards models
 
-## Install to your Galaxy server from the toolshed - search for lifelines_km_cph_tool owned by fubar2
+Uses the [lifelines](https://lifelines.readthedocs.io/en/latest/index.html) package.
+
+### Install to your Galaxy server from the toolshed - search for lifelines_km_cph_tool owned by fubar2
 
-### More at https://lazarus.name/demo/
+More at https://lazarus.name/demo/
+
+#### Using the Rossi sample recidivism data from lifelines:
 
-#### Using the Rossi sample input data from lifelines, tool outputs include:
+Runs Kaplan-Meier and generates a plot. Optional grouping variable.
+
+Plots show confidence intervals
 
 ![KM plot sample](lifelines_rossi_km.png)
-and
-![KM plot sample](lifelines_rossi_schoenfeld.png)
-and
+
+If 2 groups, runs a log-rank test for difference.
+
 ![KM plot sample](lifelines_report.png)
 
-
-Runs Kaplan-Meier and generates a plot. Optional grouping variable.
-If 2 groups, runs a log-rank test for difference.
-Plots show confidence intervals
+If a comma separated list (for example: prio, age, race, mar, fin) of covariate column names is provided,
+a Cox proportional hazards model is run, the assumption of proportionality is tested, and
+recommendations made.
+![KM plot sample](lifelines_rossi_schoenfeld.png)
 
-If a list of covariate column names is provided, these are used in a
-Cox Proportional Hazards model with tests for proportionality.
+Also included are partial plots for each covariate like these from the Rossi recidivism lifelines sample data
+used in the tool test.
 
-Should work with any tabular data with the required columns - time and status for observations.
+![C-PH partial plot samples](agepartialrossi.png)
+
+![C-PH partial plot samples](parolepartialrossi.png)
+
+Uses pandas read_csv with tabular delimiters so should work with any tabular data with the required columns - time and status for observations.
 
 Issues to https://github.com/fubar2/lifelines_tool please.
 Autogenerated so pull requests are possibly meaningless but regeneration of a new version should work.