# HG changeset patch # User galaxy-australia # Date 1730690875 0 # Node ID 1957f881bdf40c2ba5b0c8a422d066d5a664d52a planemo upload for repository https://github.com/usegalaxy-au/tools-au/tree/master/tools/dorado commit 8f48f7ee85162eeaa9c0247c7bb7d699f84d6ca7 diff -r 000000000000 -r 1957f881bdf4 README.md --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/README.md Mon Nov 04 03:27:55 2024 +0000 @@ -0,0 +1,48 @@ + +## Tool versions + +Dorado is distributed on +[DockerHub](https://hub.docker.com/r/nanoporetech/dorado/tags) by nanoporetech. +The containers are identified by sha256 hash, but not tagged with a version. + +We can still use the containers and display the dorado version by hard-coding +both dorado version and container hash into the wrapper (see `macros.xml`). +Unfortunately you have to pull a >6 GB container and run `dorado --version` just +to check the tool version. This also prevents auto-updates of this wrapper. + +You can update the list of models at the same time (see +below). **You must do this when you update the wrapper**. + +## Basecalling models + +The models are bundled in the container at `/models` and made available by the +`dorado_models.loc` file. + +The columns are `value`, `container_hash`, `name` and `path`. + +To update the list, modify `tool-data/dorado_models.loc.sample`. + +Because models can be added and removed, models are listed **per container** in +the loc file. + +Here's some code to update the loc file with models from the container with hash +`1c65eb070a9fc1d88710c4dc09b06541f96fdd28`. + +```bash +export DORADO_HASH="1c65eb070a9fc1d88710c4dc09b06541f96fdd28" + +apptainer exec "docker://nanoporetech/dorado:sha${DORADO_HASH}" \ + ls /models | \ + awk -v hash="${DORADO_HASH}" '{print hash "_" $0 "\t" hash "\t" $0 "\t/models/" $0}' \ + > tool-data/dorado_models.loc.sample +``` + +The loc file doesn't have a header, so you can keep it sorted. + +```bash +cp tool-data/dorado_models.loc.sample \ + tool-data/dorado_models.loc.sample.old && +sort -t$'\t' -k1,1V tool-data/dorado_models.loc.sample.old \ + > tool-data/dorado_models.loc.sample +``` + diff -r 000000000000 -r 1957f881bdf4 dorado_trimming.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/dorado_trimming.xml Mon Nov 04 03:27:55 2024 +0000 @@ -0,0 +1,102 @@ + + for Oxford Nanopore (ONT) DNA reads + + macros.xml + + + + trimmed.bam + +&& + +dorado summary +trimmed.bam +> summary.tsv + + + ]]> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + `__ basecaller. + +This tool scans existing, basecalled datasets for adapter and/or primer +sequences at either end, and trims any such found sequences. + +**If you have raw (un-basecalled) data, you can trim them during +basecalling with the Dorado tool on Galaxy**. + +Note that if you intend to demultiplex the reads later, trimming +adapters and primers may result in some portions of the flanking regions +of the barcodes being removed, which could interfere with correct +demultiplexing. + +The **Don't trim primers** option can be used to prevent the trimming of +primer sequences. In this case only adapter sequences will be trimmed. + +The output of will always be unaligned records, regardless of whether +the input is aligned/sorted or not. + +Custom primer trimming +---------------------- + +The software automatically searches for primer sequences used in Oxford +Nanopore kits. However, you can specify an alternative set of primer +sequences to search by adding a FASTA file of primer sequences in the +**Custom primer sequences** option. The record names of the sequences do +not matter. Note that if you use this option the normal primer sequences +built-in to the dorado software will not be searched for. + +RNA adapter trimming +-------------------- + +Adapters for RNA002 and RNA004 kits are automatically trimmed during +basecalling. However, unlike in DNA, the RNA adapter cannot be trimmed +post-basecalling. + ]]> + + diff -r 000000000000 -r 1957f881bdf4 macros.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/macros.xml Mon Nov 04 03:27:55 2024 +0000 @@ -0,0 +1,27 @@ + + + 0.8.2+6b413c9 + ae1d5e75f94041e4fd7af4a7ed6e6432b0eaea29 + + + nanoporetech/dorado:sha@CONTAINER_HASH@ + + + + + dorado + + + + + + @misc{dorado, + title = {Dorado}, + author = {{Oxford Nanopore}}, + year = {2024}, + url = {https://github.com/nanoporetech/dorado/}, + } + + + + diff -r 000000000000 -r 1957f881bdf4 test-data/FAL00375_473bf0ed_0.ten_reads.0_0.fast5.tar Binary file test-data/FAL00375_473bf0ed_0.ten_reads.0_0.fast5.tar has changed diff -r 000000000000 -r 1957f881bdf4 test-data/FAL00375_473bf0ed_0.ten_reads.bam Binary file test-data/FAL00375_473bf0ed_0.ten_reads.bam has changed diff -r 000000000000 -r 1957f881bdf4 test-data/FAL00375_473bf0ed_0.ten_reads.pod5 Binary file test-data/FAL00375_473bf0ed_0.ten_reads.pod5 has changed diff -r 000000000000 -r 1957f881bdf4 test-data/SQK-RBK114_BC01_BC04_unclassified.pod5 Binary file test-data/SQK-RBK114_BC01_BC04_unclassified.pod5 has changed diff -r 000000000000 -r 1957f881bdf4 test-data/custom_primers.fasta.gz Binary file test-data/custom_primers.fasta.gz has changed diff -r 000000000000 -r 1957f881bdf4 test-data/dorado_models.loc --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/dorado_models.loc Mon Nov 04 03:27:55 2024 +0000 @@ -0,0 +1,80 @@ +ae1d5e75f94041e4fd7af4a7ed6e6432b0eaea29_dna_r9.4.1_e8_fast@v3.4 ae1d5e75f94041e4fd7af4a7ed6e6432b0eaea29 dna_r9.4.1_e8_fast@v3.4 /models/dna_r9.4.1_e8_fast@v3.4 +ae1d5e75f94041e4fd7af4a7ed6e6432b0eaea29_dna_r9.4.1_e8_fast@v3.4_5mCG@v0.1 ae1d5e75f94041e4fd7af4a7ed6e6432b0eaea29 dna_r9.4.1_e8_fast@v3.4_5mCG@v0.1 /models/dna_r9.4.1_e8_fast@v3.4_5mCG@v0.1 +ae1d5e75f94041e4fd7af4a7ed6e6432b0eaea29_dna_r9.4.1_e8_fast@v3.4_5mCG_5hmCG@v0 ae1d5e75f94041e4fd7af4a7ed6e6432b0eaea29 dna_r9.4.1_e8_fast@v3.4_5mCG_5hmCG@v0 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tool_data_table_conf.xml.sample --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_data_table_conf.xml.sample Mon Nov 04 03:27:55 2024 +0000 @@ -0,0 +1,6 @@ + + + value, tool_version, name, path + +
+
\ No newline at end of file diff -r 000000000000 -r 1957f881bdf4 tool_data_table_conf.xml.test --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_data_table_conf.xml.test Mon Nov 04 03:27:55 2024 +0000 @@ -0,0 +1,6 @@ + + + value, tool_version, name, path + +
+
\ No newline at end of file