changeset 0:bb199421f731 draft default tip

planemo upload for repository https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/lfq_protein_quant commit 26ff08776f90f96646598a19cfcf57d42aa4a43b
author galaxyp
date Tue, 02 Oct 2018 16:30:33 -0400
parents
children
files lfq_protein_quant.xml quantitation.r test-data/meta.tab test-data/moff.tab test-data/quantitation.tsv test-data/summarised_proteins.tsv
diffstat 6 files changed, 2105 insertions(+), 0 deletions(-) [+]
line wrap: on
line diff
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/lfq_protein_quant.xml	Tue Oct 02 16:30:33 2018 -0400
@@ -0,0 +1,98 @@
+<tool id="lfq_protein_quant" name="Label free protein" version="1.0">
+    <description>
+        summarisation and quantitation
+    </description>
+    <requirements>
+        <requirement type="package" version="2.2.0">bioconductor-msnbase</requirement>
+        <requirement type="package" version="2.12.0">bioconductor-mzr</requirement>
+        <requirement type="package" version="1.2.1">r-tidyverse</requirement>
+        <requirement type="package" version="1.1_18_1">r-lme4</requirement>
+        <requirement type="package" version="0.1.0">r-furrr</requirement>
+        <requirement type="package" version="0.7.5">r-msqrob</requirement>
+    </requirements>
+    <command detect_errors="exit_code">
+    <![CDATA[
+        ln -s '${moff_file}' moff.tsv &&
+        ln -s '${meta_file}' meta.tsv &&
+        Rscript '$__tool_directory__/quantitation.r'
+            moff.tsv
+            meta.tsv
+            $only_summarisation
+            \${GALAXY_SLOTS:-4}
+    ]]>
+    </command>
+    <inputs>
+        <param name="moff_file" type="data" format="tabular"
+               label="Peptide summary output from moFF or other peptide quantitation tools" />
+        <param name="meta_file" type="data" format="tabular" label="Metadata with sample names and condition" />
+        <param name="only_summarisation" type="boolean" truevalue="1" falsevalue="0"
+            label="Only summarisiation" help="This option will deactivate the quantifiation of data." />
+
+    </inputs>
+    <outputs>
+        <data format="tabular" name="quant" from_work_dir="quantitation.tsv" label="${tool.name} on ${on_string}: quantification">
+            <filter>not only_summarisation</filter>
+        </data>
+        <data format="tabular" name="summary" from_work_dir="summarised_proteins.tsv" label="${tool.name} on ${on_string}: summary"/>
+    </outputs>
+    <tests>
+        <test>
+            <param name="moff_file" value="moff.tab"/>
+            <param name="meta_file" value="meta.tab"/>
+            <param name="only_summerisation" value="true"/>
+            <output name="quant" file="quantitation.tsv" />
+            <output name="summary" file="summarised_proteins.tsv" />
+        </test>
+    </tests>
+    <help>
+        <![CDATA[
+**What it does**
+
+Protein summarisation and label free quantitation.
+
+----
+
+    **Inputs** 
+
+    - Quantification input: Tabular file with the summary output from moFF or in case other tools were used for peptide quantitation with the following columns: 'peptides' containing the amino acid sequence; 'prot' with the Uniprot Accession and then one column per sample with the quantitation values.
+
+            ::
+
+                  peptides     prot       sample1    sample2
+                  AAABDEK      B9DM54     1809446    563862
+                  TELATASDR    Q9CFE8     294282     457023
+                  AMGLATK      P85660     194023     428277
+                    ...
+                    ...
+
+
+    - Metadata input: Separate columns with sample names, condition and optionally also lab and machine. Sample names must match exactly the sample names from the peptide quantitation columns in the previous tabular file.
+
+
+            ::
+
+                  sample     condition 
+                  sample1    healthy
+                  sample2    disease
+                    ...
+                    ...
+
+
+    **Options** 
+
+    - Summarisation only: Summarisation is done through robust regression to take also the peptide effect into account. In case only sample column is provided median protein intensity is calculated.
+    - Summarisation and quantification: Relative quantification is performed according to the information provided in the metadata file. 
+
+
+    **Outputs** 
+
+    - Summarised protein output: Uniprot accession and quantitation values per sample and protein
+    - Quantification output: Uniprot accession, comparison between conditions, fold change, p-value, q-value
+
+        ]]>
+    </help>
+    <citations>
+        <citation type="doi">10.1074/mcp.M115.055897</citation>
+        <citation type="doi">10.1093/bioinformatics/btr645</citation>
+    </citations>
+</tool>
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/quantitation.r	Tue Oct 02 16:30:33 2018 -0400
@@ -0,0 +1,452 @@
+#################################
+library(tidyverse)
+library(furrr)
+library(lme4)
+library(MSnbase)
+library(MSqRob)
+
+##Import and preprocess data
+############################
+MSnSet2df = function(msnset){
+  ## Converts Msnset to a tidy dataframe
+  ## Always creates feature and vector column so these shouldn't be defined by user.
+  ## convenient for downstream analysis steps.
+  if(any(c("sample", "feature", "expression") %in% c(colnames(fData(msnset)),colnames(pData(msnset))))){
+    stop("Column names in the \"fData\" or \"pData\" slot of the \"msnset\" object cannot be named
+         \"sample\", \"feature\" or \"expression\". Please rename these columns before running the analysis.")
+  }
+
+  dt <- as.data.frame(Biobase::exprs(msnset)) %>% mutate(feature = rownames(.)) %>%
+    gather(sample, expression, - feature, na.rm=TRUE)
+  dt <- fData(msnset) %>% mutate(feature = rownames(.)) %>% left_join(dt,. , by = 'feature')
+  dt <- pData(msnset) %>% mutate(sample = rownames(.)) %>% left_join(dt,. , by = 'sample')
+  as_data_frame(dt)
+}
+
+## robust summarisation
+do_robust_summaristion = function(msnset, group_var = Proteins, keep_fData_cols = NULL, nIter = 20,
+                                  sum_fun = summarizeRobust){
+  ## TODO use funture_map instead of mutate to speed up
+  ## Uses assumption that featureNames and sampleNames exist in every msnset
+  ## Can also be used for multiple rounds of normalization, e.g. first from PSMs to peptides, then from peptides to proteins
+  system.time({## Time how long it takes
+    group_var <- enquo(group_var) ;#group_var = quo(Proteins)
+  ## Make tidy dataframe from Msnset
+    df <- MSnSet2df(msnset)
+    ## Do summarisision according defined groups
+    dt <- filter(df, !is.na(expression)) %>% group_by(!!group_var) %>%
+      mutate(expression = sum_fun(expression, feature, sample, nIter = nIter)) %>%
+      dplyr::select(!!group_var, sample, expression) %>%
+      ## collapse to one value per group
+      distinct
+    ## Construct an Msnset object from dataframe
+    dt_exprs <- spread(dt, sample, expression) %>% ungroup
+    exprs_data <- dplyr::select(dt_exprs, - !!group_var) %>% as.matrix
+    rownames(exprs_data) <- as.character(pull(dt_exprs, !!group_var))
+
+    fd <- dplyr::select(dt_exprs,!!group_var)
+
+    ##Select the group variable and all variables you want to keep
+    if (!is.null(keep_fData_cols)){
+      fd_ext <- dplyr::select(df, !!group_var, one_of(keep_fData_cols)) %>% distinct
+      if(nrow(fd)!=nrow(fd_ext)){
+        stop("Values in the \"group_var\" column can only correspond to a single value in the \"keep_fData_cols\" column.")
+      }
+      fd <- left_join(fd,fd_ext)
+    }
+
+    fd <- as.data.frame(fd)
+    rownames(fd) <- as.character(pull(fd, !!group_var))
+    out <- MSnSet(exprs_data, fData = AnnotatedDataFrame(fd) , pData = pData(msnset)[colnames(exprs_data),,drop = FALSE])
+  }) %>% print
+  out
+}
+
+summarizeRobust <- function(expression, feature, sample, nIter=100,...) {
+  ## Assumes that intensities mx are already log-transformed
+  ## characters are faster to construct and work with then factors
+  feature <- as.character(feature)
+  ##If there is only one 1 peptide for all samples return expression of that peptide
+  if (length(unique(feature)) == 1L) return(expression)
+  sample <- as.character(sample)
+  ## modelmatrix breaks on factors with 1 level so make vector of ones (will be intercept)
+  if (length(unique(sample)) == 1L) sample = rep(1,length(sample))
+
+  ## sum contrast on peptide level so sample effect will be mean over all peptides instead of reference level
+  X = model.matrix(~ -1 + sample + feature,contrasts.arg = list(feature = 'contr.sum'))
+  ## MasS::rlm breaks on singulare values.
+  ## check with base lm if singular values are present.
+  ## if so, these coefficients will be zero, remove this collumn from model matrix
+  ## rinse and repeat on reduced modelmatrx till no singular values are present
+  repeat {
+    fit = .lm.fit(X,expression)
+    id = fit$coefficients != 0
+    X = X[ , id, drop =FALSE]
+    if (!any(!id)) break
+  }
+  ## Last step is always rlm
+  fit = MASS::rlm(X,expression,maxit = nIter,...)
+  ## Only return the estimated effects effects as summarised values
+  sampleid = seq_along(unique(sample))
+  return(X[,sampleid,drop = FALSE] %*% fit$coefficients[sampleid])
+}
+
+
+
+
+
+
+
+
+## mixed models
+###############
+setGeneric (
+  name= "getBetaB",
+  def=function(model,...){standardGeneric("getBetaB")}
+)
+
+.getBetaBMermod = function(model) {
+  betaB <- c(as.vector(getME(model,"beta")),as.vector(getME(model,"b")))
+  names(betaB) <- c(colnames(getME(model,"X")),rownames(getME(model,"Zt")))
+  betaB
+}
+setMethod("getBetaB", "lmerMod", .getBetaBMermod)
+
+.getBetaBGlm = function(model) 
+  model$coefficients
+
+setGeneric (
+  name= "getVcovBetaBUnscaled",
+  def=function(model,...){standardGeneric("getVcovBetaBUnscaled")}
+)
+
+setMethod("getBetaB", "glm", .getBetaBGlm)
+
+.getVcovBetaBUnscaledMermod = function(model){
+  ## TODO speed up (see code GAM4)
+  p <- ncol(getME(model,"X"))
+  q <- nrow(getME(model,"Zt"))
+  Ct <- rbind2(t(getME(model,"X")),getME(model,"Zt"))
+  Ginv <- solve(tcrossprod(getME(model,"Lambda"))+Diagonal(q,1e-18))
+  vcovInv <- tcrossprod(Ct)
+  vcovInv[((p+1):(q+p)),((p+1):(q+p))] <- vcovInv[((p+1):(q+p)),((p+1):(q+p))]+Ginv
+
+ solve(vcovInv)
+}
+
+setMethod("getVcovBetaBUnscaled", "lmerMod", .getVcovBetaBUnscaledMermod)
+
+.getVcovBetaBUnscaledGlm = function(model)
+  ## cov.scaled is scaled with the dispersion, "cov.scaled" is without the dispersion!
+  ## MSqRob::getSigma is needed because regular "sigma" function can return "NaN" when sigma is very small!
+  ## This might cause contrasts that can be estimated using summary() to be NA with our approach!
+  summary(model)$cov.scaled/MSqRob::getSigma(model)^2
+
+setMethod("getVcovBetaBUnscaled", "glm", .getVcovBetaBUnscaledGlm)
+
+## Estimate pvalues contrasts
+contrast_helper = function(formula, msnset, contrast = NULL){
+  ## Gives back the coefficients you can use to make contrasts with given the formula and dataset
+  ## If a factor variable is specified (that is present in the formula) all the possible contrasts
+  ## within this variable are returned
+  contrast <- enquo(contrast) ;#contrast = quo(condition)
+  df <- MSnSet2df(msnset)
+  all_vars <- formula %>% terms %>% delete.response %>% all.vars
+  names(all_vars) <- all_vars
+  df[,all_vars] <- map2_dfr(all_vars,df[,all_vars],paste0)
+  coefficients <- c("(Intercept)", df %>% dplyr::select(all_vars) %>% unlist %>% unique %>% as.character)
+  if (contrast != ~NULL) {
+    c <- pull(df,!! contrast) %>% unique %>% sort %>% as.factor
+    comp <- combn(c,2,simplify = FALSE)
+    ## condIds = map(comp,~which( coefficients %in% .x))
+    ## L = rep(0,length(coefficients))
+    ## L = sapply(condIds,function(x){L[x]=c(-1,1);L})
+    ## rownames(L) = coefficients
+    ## colnames(L) = map_chr(comp, ~paste(.x,collapse = '-'))
+    condIds <- map(comp, ~which(coefficients %in% .x))
+    L <- rep(0,nlevels(c))
+    L <- sapply(comp,function(x){L[x]=c(-1,1);L})
+    rownames(L) <- levels(c)
+    colnames(L) <- map_chr(comp, ~paste(rev(.x),collapse = '-'))
+    L
+  } else coefficients
+}
+
+setGeneric (
+  name= "getXLevels",
+  def=function(model,...){standardGeneric("getXLevels")}
+)
+
+.getXLevelsGlm = function(model)
+  map2(names(model$xlevels), model$xlevels, paste0) %>% unlist
+
+setMethod("getXLevels", "glm", .getXLevelsGlm)
+
+.getXLevelsMermod = function(model)
+  getME(model,"flist") %>% map(levels) %>% unlist %>% unname
+
+setMethod("getXLevels", "lmerMod", .getXLevelsMermod)
+
+contEst <- function(model, contrasts, var, df, lfc = 0){
+  #TODO only contrast of random effect possible and not between fixed regression terms
+  betaB <- getBetaB(model)
+  vcov <- getVcovBetaBUnscaled(model)
+  coefficients <- names(betaB)
+  id <- coefficients %in% rownames(contrasts)
+
+  coefficients <- coefficients[id]
+  vcov <- vcov[id,id]
+  betaB <- betaB[id]
+
+  xlevels <- getXLevels(model)
+  id <- !apply(contrasts,2,function(x){any(x[!(rownames(contrasts) %in% xlevels)] !=0)})
+  contrasts <- contrasts[coefficients, id, drop = FALSE]
+  ## If no contrasts could be found, terminate
+  if (is.null(colnames(contrasts))) return(new_tibble(list()))
+
+  se <- sqrt(diag(t(contrasts)%*%vcov%*%contrasts)*var)
+  logFC <- (t(contrasts)%*%betaB)[,1]
+  
+  ### Addition to allow testing against another log FC (lfc)
+  ### See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654802/
+  
+  lfc <- abs(lfc)
+  aest <- abs(logFC)
+  
+  Tval <- setNames(rep(0, length(logFC)),names(se))
+  tstat.right <- (aest - lfc)/se
+  tstat.left <- (aest + lfc)/se
+  pval <- pt(tstat.right, df = df, lower.tail = FALSE) +
+    pt(tstat.left, df = df, lower.tail = FALSE)
+  tstat.right <- pmax(tstat.right, 0)
+  fc.up <- (logFC >= lfc)
+  fc.up[is.na(fc.up)] <- FALSE
+  fc.down <- (logFC < -lfc)
+  fc.down[is.na(fc.down)] <- FALSE
+  Tval[fc.up] <- tstat.right[fc.up]
+  Tval[fc.down] <- -tstat.right[fc.down]
+  Tval[is.na(logFC)] <- NA
+  
+  new_tibble(list(contrast = colnames(contrasts),
+                  logFC = logFC,
+                  se = se,
+                  t = Tval,
+                  df = rep(df, length(se)),
+                  pvalue = pval))
+}
+
+do_lmerfit = function(df, form, nIter = 10, tol = 1e-6, control = lmerControl(calc.derivs = FALSE)){
+  fit <- lmer(form, data = df, control = control)
+  ##Initialize SSE
+  res <- resid(fit)
+  ## sseOld=sum(res^2)
+  sseOld <- fit@devcomp$cmp['pwrss']
+  while (nIter > 0){
+    nIter = nIter-1
+    fit@frame$`(weights)` <- MASS::psi.huber(res/(mad(res)))
+    fit <- refit(fit)
+    res <- resid(fit)
+    ## sse=sum(res^2)
+    sse <- fit@devcomp$cmp['pwrss']
+    if(abs(sseOld-sse)/sseOld <= tol) break
+    sseOld <- sse
+  }
+  return(fit)
+}
+
+calculate_df = function(df, model, vars){
+  ## Get all the variables in the formula that are not defined in vars
+  form <- attributes(model@frame)$formula
+  vars_formula <- all.vars(form)
+  vars_drop <- vars_formula[!vars_formula %in% vars]
+  ## Sum of number of columns -1 of Zt mtrix of each random effect that does not involve a variable in vars_drop
+  mq <- getME(model,'q_i')
+  id <- !map_lgl(names(mq),~{any(stringr::str_detect(.x,vars_drop))})
+  p <- sum(mq[id]) - sum(id)
+  ## Sum of fixed effect parameters that do not involve a variable in vars_drop
+  mx <- getME(model,'X')
+  id <- !map_lgl(colnames(mx),~{any(stringr::str_detect(.x,vars_drop))})
+  p <- p + sum(id)
+
+  ## n is number of sample because 1 protein defined per sample
+  n <- n_distinct(df$sample)
+  n-p
+}
+
+do_mm = function(formulas, msnset, group_vars = feature,type_df = 'traceHat'
+                  , contrasts = NULL, lfc = 0, p.adjust.method = "BH", max_iter = 20L
+                  , squeeze_variance = TRUE
+               , control = lmerControl(calc.derivs = FALSE)
+                 ## choose parallel = plan(sequential) if you don't want parallelisation
+               ## , parallel_plan = plan(cluster, workers = makeClusterPSOCK(availableCores()))
+               , parallel = TRUE, cores = availableCores()
+                 ){
+  if(!(type_df %in% c("conservative", "traceHat")))
+    stop("Invalid input `type_df`.")
+                   
+  system.time({## can take a while
+    if (parallel){
+      cl <- makeClusterPSOCK(cores)
+      plan(cluster, workers = cl)   
+    } else {
+    plan(sequential)}
+
+    ## future::plan(parallel_plan,gc = TRUE)
+    formulas <-  map(c(formulas), ~update(.,expression ~ . ))
+    group_vars <- enquo(group_vars) # group_var = quo(protein)
+    df <- MSnSet2df(msnset)
+
+    ## Glm adds variable name to levels in catogorical (eg for contrast) 
+    ## lme4 doesnt do this for random effect, so add beforehand
+    ## Ludger needs this for Hurdle 
+    df = formulas %>% map(lme4:::findbars) %>% unlist %>% map_chr(all.vars) %>% unique %>%
+      purrr::reduce(~{mutate_at(.x,.y,funs(paste0(.y,.)))}, .init=df)
+
+    cat("Fitting mixed models\n")
+    ## select only columns needed for fitting
+    df_prot <- df %>%
+      group_by_at(vars(!!group_vars)) %>% nest %>%
+      mutate(model = furrr::future_map(data,~{
+        for (form in formulas){
+          fit = try(do_lmerfit(.x, form, nIter = max_iter,control = control))
+          if (class(fit) == "lmerMod") return(fit)
+        }
+        fit
+      }))
+
+    ## Return also failed ones afterward
+    df_prot_failed <- filter(df_prot, map_lgl(model,~{class(.x) != "lmerMod"}))
+    df_prot <- filter(df_prot, map_lgl(model, ~{class(.x)=="lmerMod"}))
+
+    if(nrow(df_prot) == 0) {print("No models could be fitted"); return(df_prot_failed)}
+
+    df_prot <-
+      mutate(df_prot
+           , formula = map(model,~{attributes(.@frame)$formula})
+             ## get trace hat df for squeezeVar
+           , df = map_dbl(model, ~getDf(.x))
+           , sigma = map_dbl(model,~{MSqRob::getSigma(.x)})) %>%
+      ## Squeeze variance
+      bind_cols(as_data_frame(MSqRob::squeezeVarRob(.$sigma^2, .$df, robust = TRUE))) %>%
+      ## mutate(var_protein = ifelse(squeeze_variance,var.post,sigma^2),
+      mutate(var_protein = if (squeeze_variance) var.post else sigma^2,
+             df_post = df + df.prior
+           , df_protein =
+               if (type_df == "conservative")
+                 ## Calculate df on protein level, assumption is that there is only one protein value/run,
+                 map2_dbl(data, model,~calculate_df(.x,.y, vars = colnames(pData(msnset))))
+               else if (type_df == "traceHat")
+                 ## Alternative: MSqRob implementation with trace(Hat):
+                 if(squeeze_variance) df_post else df
+             )
+   
+    ## Calculate fold changes and p values for contrast
+    cat("Estimating p-values contrasts\n")
+    df_prot <- df_prot %>%
+      mutate(contrasts =  furrr::future_pmap(list(model = model, contrasts = list(contrasts),
+                                                     var = var_protein,
+                                                     df = df_protein, lfc = lfc), contEst))  %>%
+      ## Calculate qvalues BH
+      select_at(vars(!!group_vars, contrasts)) %>%
+      unnest %>% 
+      group_by(contrast) %>%
+      mutate(qvalue = p.adjust(pvalue, method = p.adjust.method)) %>%
+      group_by_at(vars(!!group_vars)) %>% nest(.key = contrasts) %>%
+      left_join(df_prot,.)
+  }
+  ) %>% print
+  if (parallel) stopCluster(cl)
+  bind_rows(df_prot,df_prot_failed)
+}
+
+read_moff = function(moff,meta){
+  print('START READING MOFF DATA')
+  set = readMSnSet2(moff, ecol = -c(1,2),fnames = 'peptide',
+                    sep = '\t',stringsAsFactors = FALSE)
+  colnames(fData(set)) = c('peptide','protein')
+  pd = read_tsv(meta) %>% column_to_rownames('sample') %>% as.data.frame
+
+  ## fix msnbase bug 1
+  ## if there is only 1 sample. Msnbase doesn't name it 
+  if (length(sampleNames(set) ==1))
+    sampleNames(set) = rownames(pd)
+
+  pData(set) = pd
+  ## fix msnbase bug 2
+  ## bug in msnbase in summarisation (samplenames should be alphabetically)
+  sample_order = order(sampleNames(set))
+  set = MSnSet(exprs(set)[,sample_order,drop = FALSE]
+             , fData =  AnnotatedDataFrame(fData(set))
+             , pData = AnnotatedDataFrame(pData(set)[sample_order,,drop = FALSE]))
+  print('END READING MOFF DATA')
+  set
+}
+
+preprocess = function(set){
+  print('START PREPROCESSING')
+  if (ncol(set) == 1){
+    exprs(set)[0 == (exprs(set))] <- NA
+    set = log(set, base = 2)
+    ## keep smallest unique groups
+    groups2 <- smallestUniqueGroups(fData(set)$protein,split = ',')
+    sel <- fData(set)$protein %in% groups2
+    set <- set[sel,]
+  } else {
+    ## normalisation
+    exprs(set)[0 == (exprs(set))] <- NA
+    set <- normalize(set, 'vsn')
+    ## keep smallest unique groups
+    groups2 <- smallestUniqueGroups(fData(set)$protein,split = ',')
+    sel <- fData(set)$protein %in% groups2
+    set <- set[sel,]
+    ## remove peptides with less then 2 observations
+    sel <- rowSums(!is.na(exprs(set))) >= 2
+    set <- set[sel]
+  }
+  print('END PREPROCESSING')
+  set
+}
+
+summarise = function(set){
+  print('START SUMMARISATION')
+  ## Summarisation
+  if (ncol(set) == 1){
+    set = combineFeatures(set,fun="median", groupBy = fData(set)$protein,cv = FALSE)
+  } else {
+    ## set = combineFeatures(set,fun="robust", groupBy = fData(set)$protein,cv = FALSE)
+    set = do_robust_summaristion(set,protein)
+  }
+  exprs(set) %>% as.data.frame %>% rownames_to_column('protein') %>% write_tsv('summarised_proteins.tsv')
+  print('END SUMMARISATION')
+  set
+}
+
+quantify = function(set, cpu = 0){
+  print('START QUANTITATION')
+  if ((cpu == 0) | is.na(cpu)) cpu = availableCores()
+  print(cpu)
+  form = colnames(pData(set)) %>% paste0('(1|',.,')',collapse='+') %>% paste('~',.) %>% as.formula
+  contrasts <- contrast_helper(form, set, condition)
+  res = do_mm(formulas = form, set, group_vars = c(protein)
+            , contrasts = contrasts,type_df = 'traceHat', parallel = TRUE,cores = cpu) %>%
+    filter(!map_lgl(contrasts, is.null)) %>%
+    transmute(protein, contrasts) %>% unnest %>%
+    transmute(protein
+            , comparison = str_replace_all(contrast, 'condition', '')
+            , logFC,pvalue,qvalue) %>%
+    write_tsv('quantitation.tsv')
+  print('END QUANTITATION')
+}
+
+args = commandArgs(trailingOnly=TRUE)
+moff = args[1]
+meta = args[2]
+summarise_only = args[3]
+cpu = strtoi(args[4])
+
+res = read_moff(moff, meta) %>%
+  preprocess %>%
+  summarise
+if (summarise_only != 1)
+  quantify(res, cpu)
+
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/meta.tab	Tue Oct 02 16:30:33 2018 -0400
@@ -0,0 +1,9 @@
+sample	condition
+sumIntensity_HEK.Ecoli_7.1_replicate1	ecoli_7
+sumIntensity_HEK.Ecoli_3.1_replicate2	ecoli_3
+sumIntensity_HEK.Ecoli_7.1_replicate2	ecoli_7
+sumIntensity_HEK.Ecoli_20.1_replicate2	ecoli_2
+sumIntensity_HEK.Ecoli_20.1_replicate1	ecoli_2
+sumIntensity_HEK.Ecoli_10.1_replicate1	ecoli_1
+sumIntensity_HEK.Ecoli_10.1_replicate2	ecoli_1
+sumIntensity_HEK.Ecoli_3.1_replicate1	ecoli_3
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/moff.tab	Tue Oct 02 16:30:33 2018 -0400
@@ -0,0 +1,226 @@
+peptide	prot	sumIntensity_HEK+Ecoli_7:1_replicate1	sumIntensity_HEK+Ecoli_3:1_replicate2	sumIntensity_HEK+Ecoli_7:1_replicate2	sumIntensity_HEK+Ecoli_20:1_replicate2	sumIntensity_HEK+Ecoli_20:1_replicate1	sumIntensity_HEK+Ecoli_10:1_replicate1	sumIntensity_HEK+Ecoli_10:1_replicate2	sumIntensity_HEK+Ecoli_3:1_replicate1
+AAAAAAALQAK	P36578	16457063.0	18431026.0	19450004.0	11017968.0	17443480.0	19442622.0	17946480.0	17091952.0
+AAAAAWEEPSSGNGTAR	Q9P258	506766.4375	435665.75	384355.5	299177.03125	493421.59375	483558.625	395972.71875	490540.625
+AAAAPGASPSPGGDAAWSEAGPGPRPLAR	P52701	457023.8125	433836.84375	347959.75	303366.21875	322148.6875	409149.28125	408018.96875	349124.15625
+AAADEWDER	P25738	4561047.5	11161413.0	3260742.5	1931902.5	678626.0	3053197.5	1516088.375	10162857.0
+AAAEDVNVTFEDQQK	Q9NQP4	517966.65625	499305.28125	394040.6875	389488.65625	383622.40625	348601.59375	434484.9375	395419.15625
+AAAEIYEEFLAAFEGSDGNKVK	O15042	358118.0625	485612.84375	372646.78125	299831.15625	365937.15625	333926.21875	307738.84375	399245.0
+AAAEVNQDYGLDPK	P07954	1933341.125	1730361.25	1742818.25	1650747.5	1676571.125	1744116.5	1513292.375	2167048.0
+AAAFEEQENETVVVK	Q9Y490	218363.04688	165289.4375	212558.14063	149998.10938	241045.25	210504.34375	181987.15625	190900.28125
+AAAFEGELIPASQIDR	P0A7J3	3454944.0	7286439.0	2284797.25	1726430.25	720417.1875	3044899.25	2287418.0	5598338.0
+AAAFEQLQK	O94826	2098420.0	2196475.75	2033756.875	1661140.625	2205855.75	1884663.625	1983980.375	1796414.625
+AAAGAAATHLEVAR	Q96S52	332332.1875	513240.96875	312199.375	298522.34375	341629.84375	258642.4375	320749.25	413272.65625
+AAAGEFADDPCSSVK	P35221	788848.0625	546523.6875	628515.8125	594441.0	539007.75	622987.75	462828.46875	703339.1875
+AAAGGQGSAVAAEAEPGKEEPPAR	Q9GZT9	274049.40625	204947.25	214794.375	205112.40625	222377.03125	241137.64063	226932.35938	203385.39063
+AAAIGIDLGTTYSCVGVFQHGK	P0DMV8, P0DMV9	2007747.375	3024701.75	1874377.625	1800173.0	2602331.75	2433892.25	1851966.25	2638740.75
+AAALEFLNRFEEAK	P31948	387500.03125	322913.0	275486.875	245810.70313	493922.65625	404116.4375	257749.625	321231.78125
+AAALEFLNRFEEAKR	P31948	364801.9375	361638.4375	504704.21875	257849.95313	301058.125	316057.84375	230942.85938	299150.78125
+AAALEQFK	Q13423	1479661.625	2418792.5	1229556.125	884897.125	1111873.5	1475850.5	1105625.0	1862347.125
+AAAMANNLQK	Q14498	1153741.875	3403271.75	2368509.75	1117940.5	738854.75	815364.3125	518996.40625	2033955.875
+AAANEQLTR	Q9NX63	177701888.0	261647520.0	291490880.0	65584816.0	256114944.0	209830688.0	221604880.0	258008128.0
+AAAPAPEEEMDECEQALAAEPK	P26641	157338.82813	146486.07813	188801.14063	162740.34375	134355.15625	169129.875	135813.92188	159674.34375
+AAAPAPVSEAVCR	P20810	415805.65625	766174.125	402396.40625	324595.8125	416173.71875	402875.78125	355104.34375	464567.75
+AAAPGVEDEPLLR	P31350	389110.0	557407.6875	322029.40625	357629.65625	409953.59375	835641.875	374259.3125	432882.65625
+AAAQLLQSQAQQSGAQQTK	Q9NVA2	681580.0	769884.0	555384.0625	536991.125	584127.875	626285.6875	757610.71875	605575.3125
+AAASTDYYK	P08559	1745518.25	2333747.25	1864745.875	1980362.375	1901938.375	1935263.25	1381518.0	1841983.0
+AAATAEEPDPK	Q99733	2734416.75	1629302.875	3566302.75	596659.75	3531444.75	1277103.875	5087164.5	1580173.5
+AAATLTSKLYSLLFRR	Q9UDW1	274540.5	342699.4375	347168.18751	332315.84376	154670.5625	220738.48438	122541.99219	247966.19530999998
+AAATPESQEPQAK	P49006	9440659.0	8302341.5	7931919.5	3302175.75	6371163.0	7315403.5	10252216.0	11276111.0
+AAAVLPVLDLAQR	P19404	678908.8125	856869.0	446169.90625	539676.875	515150.46875	570107.75	580731.5	755040.875
+AAAYNLVQHGITNLCVIGGDGSLTGANIFR	P17858	150314.71875	183069.79688	158230.60938	119872.25781	152153.07813	170457.64063	140610.73438	133678.5625
+AAAYSAQVQPVDGATR	Q9H7E9	202985.21875	300835.84375	229441.875	188218.34375	303109.3125	251189.4375	195645.32813	210041.0625
+AACDLVR	P55060	872022.1875	1410906.875	1242594.5	651941.4375	1106910.75	1024352.0625	835730.6875	1014368.625
+AADAEAEVASLNR	P06753	1683163.625	1935902.375	1636292.75	1372537.875	1719402.125	1807328.25	1708672.75	1837930.0
+AADAEAEVASLNRR	P06753	1544100.75	1590765.5	1926383.5	1313146.75	1356964.75	1414467.75	1366570.5	1493739.625
+AADALEEQQR	Q14980	613209.25	821710.25	588577.6875	715849.3125	612533.6875	749069.125	560475.75	545005.5625
+AADCEVEQWDSDEPIPAK	Q9UBQ7	453218.9375	550464.0625	439595.875	298535.90625	365147.9375	389253.21875	380356.59375	487347.25
+AADCEVEQWDSDEPIPAKELER	Q9UBQ7	375257.34375	445597.8125	305600.90625	259193.375	324278.28125	366561.875	349832.1875	376775.71875
+AADEEAFEDNSEEYIR	P55060	548687.0	504642.25	516831.03125	336418.03125	392263.21875	473247.1875	373003.40625	419577.6875
+AADEEAFEDNSEEYIRR	P55060	1920555.0	2474152.5	1897146.625	1324775.0	1806935.0	1729345.75	1318125.875	2395517.5
+AADEGLEVK	P15639	115103160.0	161846800.0	131593088.0	113668960.0	129641000.0	159955424.0	127616224.0	135189072.0
+AADFQLHTHVNDGTEFGGSIYQK	Q9Y277	829458.5625	1059759.0	820088.375	595366.625	729816.5625	711710.25	552610.125	712880.9375
+AADLRRAREKCEAALRAPVWAQCASR	Q9Y493	83660.9375	97753.375	55241.859379999994	74407.4375	52179.1875	99087.17188	68461.27344	114737.09375
+AADNKKPVNSWTCEDFLAVDESFQPTAVGFAEALNNK	P0AES9	374782.03125	1073745.375	178165.89063	84842.45313	58227.078129999994	317586.65625	76887.63281	619545.1875
+AADNKSLGQFNLDGINPAPR	P0A6Y8	476727.625	556992.1875	562028.75	409878.6875	531271.5625	610394.0	449127.53125	497186.28125
+AADPPAENSSAPEAEQGGAE	P67809	1216764.75	1382781.875	1327734.625	1299311.875	1230184.75	1210385.125	1277061.375	1260738.25
+AADQFDIYSSQQSK	Q7Z6I8	195096.875	242473.78125	246796.45313	157769.84375	160986.10938	249922.82813	218640.35938	235270.64063
+AADRLEQELLR	Q6PK04	603188.75	642592.0	676531.125	898076.625	503607.09375	661956.5	967021.375	506065.78125
+AADRLPNLSSPSAEGPPGPPSGPAPR	O60784	335420.34375	465945.71875	250621.85938	237410.10938	216500.10938	266107.625	278648.90625	226981.125
+AADSICDGDLVDSQIR	P35251	287150.15625	376486.09375	305919.4375	367230.6875	368645.875	270783.5625	362053.65625	277978.71875
+AADSQNSGEGNTGAAESSFSQEVSR	P12270	277749.46875	209392.14063	171475.15625	234538.29688	233402.35938	286756.96875	244354.20313	201084.59375
+AAEAAAAPAESAAPAAGEEPSKEEGEPK	P80723	485232.1875	392837.21875	370831.9375	423687.6875	275280.9375	342750.40625	296843.59375	373633.46875
+AAEAAPPTQEAQGETEPTEQAPDALEQAADTSR	Q8N163	393298.65625	341137.53125	245102.82813	234163.10938	320082.625	347362.71875	299945.96875	266847.0625
+AAEAAPPTQEAQGETEPTEQAPDALEQAADTSRR	Q8N163	584909.09375	591906.1875	249782.14063	242476.0	426763.0625	465968.17188000004	292524.21875	334111.3125
+AAEAGGAEEQYGFLTTPTK	P46821	174947.92188	317658.8125	288471.59375	151255.29688	232762.8125	195210.5	186932.9375	163187.71875
+AAEAHVDAHYYEQNEQPTGTCAACITGDNR	P55263	161952.59375	0.0	134048.07813	119756.45313	109196.78906	0.0	102006.02344	150840.0
+AAEALHGEADSSGVLAAVDATVNK	Q14554	517044.21875	646613.0625	517864.4375	257536.03125	274241.90625	286140.8125	527209.6875	553829.8125
+AAEAVAAAVGTGATTAAVMAAAGIAAIGPAK	P46821	114578.53906	111104.60938	72352.14063	75247.8125	83151.85938	101303.69531	110662.98438	120537.64844
+AAECNIVVTQPR	Q08211	9500796.0	10092312.0	9372391.0	6439289.0	8899535.0	8570160.0	7164987.0	8305028.5
+AAEDDEDDDVDTK	P06454	9554396.0	5642907.0	7957058.5	118164.16406	4425836.0	988515.375	6951661.5	3304044.25
+AAEDDEDDDVDTKK	P06454	19989763.125	60023823.0	27992851.625	39594335.5	37045608.75	50890653.0	16068953.375	52661879.5
+AAEDDEDDDVDTKKQKTDEDD	P06454	476077.71875	1074214.875	976103.75	260989.10938	800631.1875	465509.875	1540799.625	696100.3125
+AAEEEDEADPK	P20962	173704.20313	227998.82813	253521.95313	286442.8125	258559.98438	388742.96875	161354.89063	203023.375
+AAEEEDEADPKR	P20962	1384687.875	1729901.9375	3380676.64063	1447085.41406	1908058.99219	2555707.75	2258480.75	1847395.9375
+AAEEIGIK	P11586	3172130.25	3303801.5	3345036.75	2043462.75	3432530.75	3058415.75	2810141.5	2918306.0
+AAEEPSKVEEK	P29966	346288.6875	398425.28125	23912.54102	789723.3125	318863.40625	701879.4375	307064.15625	411230.15625
+AAEINGEVDDDDAGGEWRLKYERAVR	Q92614	144679.82813	151713.1875	89769.63281	83473.94531	130713.15625	147805.03125	103667.26563	107035.44531
+AAELFHQLSQALEVLTDAAAR	Q9NVM6	49059.30078	102924.60156	43793.63281	51720.86719	57911.46094	76279.21875	38605.90234	57447.37891
+AAELIANSLATAGDGLIELR	P35232	1467853.34375	3311954.125	1464810.96875	2755653.875	2647830.375	2655157.375	3080132.625	1401254.70313
+AAENNPELAAFIDECR	P07813	6343.87109	243295.3125	4990.64307	12717.686520000001	7795.913570000001	13078.40918	6991.21631	198571.48438
+AAEQYTPK	P49327	443422.90625	440923.53125	414016.59375	292009.875	398195.15625	431767.65625	457349.96875	437038.53125
+AAESLADPTEYENLFPGLK	P35606	380898.53125	457903.5625	314852.46875	321385.5	325512.4375	342994.5	362427.125	341213.0625
+AAESLTAIPEPASPQLLETPIHASQIQK	Q14676	417712.0	518017.21875	408912.75	378693.0625	366977.59375	482182.0	350338.875	703643.4375
+AAEVWMDEFKELYYHRNPR	Q8IXK2	1025027.6875	1269858.125	1012839.125	810524.75	944672.75	988035.375	933829.5625	999890.1875
+AAEWLFPLAFSKEDELLR	Q6SZW1	43075.07031	31860.820310000003	51468.65234	73645.19531	103648.86719	97488.17188	81801.125	41079.30859
+AAEWQLDQPSWSGR	Q9NVZ3	160403.48438	157672.57813	126821.36719	122459.03125	132133.32813	162733.42188	153623.46875	131857.01563
+AAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDK	P27708	274123.59375	256397.67188	216109.26563	149329.64063	231914.5	273052.28125	161647.40625	219148.57813
+AAFAPFGR	P31483	1256650.375	1165121.875	969571.125	837222.875	1191336.625	1197343.5	1086561.0	1044473.625
+AAFDDAIAELDTLSEESYK	P62258	6202557.5625	13592642.0	10899126.5	3598419.60938	10530194.5	11511309.5	9525720.5	10766430.0
+AAFGEEVDAVDTGISR	O00273	794859.625	686799.3125	934208.0625	738494.125	872900.375	1021071.9375	698938.9375	933331.25
+AAFGISDSYVDGSSFDPQRR	Q9UQ35	584056.5625	568692.8125	543462.625	447183.875	482399.90625	532065.875	471091.15625	537847.0
+AAFGLSEAGFNTACVTK	P31040	1306702.25	961031.8125	1367372.75	1182538.625	1375884.75	1269767.25	1075112.625	924780.25
+AAFLNFFR	Q5JTZ9	347756.375	210911.57813	155313.125	145964.75	219090.65625	262970.46875	145387.84375	130521.35156
+AAFQLGSPWRR	P05091	516365.0625	495663.625	547436.0	443698.84375	559692.5625	612528.0625	512100.34375	535705.5
+AAFQPVFLEVVDESYR	P0ABE2	115822.28906	146682.26563	62019.05078	37173.79688	0.0	71428.82813	0.0	142522.21875
+AAFQSLLDAQADEAVLDHPDLK	Q9UBI1	106326.92188	164644.53125	150714.39063	101208.10938	126031.99219	151037.92188	118278.03125	110120.17969
+AAFTAFEEAQLPR	Q96CT7	361588.6875	1259112.59375	1232726.46875	857117.875	904665.1875	936289.4375	940827.3125	1237296.14063
+AAFTVSLDPGPLEQFPHSMEPQLR	Q9UKD2	208784.6875	1172880.625	209576.84375	175708.5625	218716.82813	203022.625	223072.10938	237121.04688
+AAFVLPEFAR	P19623	1183178.5	1219394.5	1259658.5	1018063.5625	1516009.0	1271241.25	1226224.0	1539150.375
+AAGASDVVLYK	Q9NSD9	1375064.125	1330516.0	1272506.75	1077785.25	1224280.75	1281444.125	1162545.75	1219108.5
+AAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE	P0A8T7	77614.39063	181254.48438	18381.50977	31839.6582	42540.87891	65422.58203	15221.41016	173854.70313
+AAGEKPENGVFWESAGEGEYTVADITK	P0A6Z3	118248.45313	182313.78125	87615.14844	0.0	0.0	0.0	0.0	165046.35938
+AAGGIELFVGGIGPDGHIAFNEPGSSLVSR	P46926	273174.59375	339507.46875	141072.25	107084.46875	152116.71875	170351.95313	88205.14063	124617.74219
+AAGIDEQENWHEGKENIR	P28838	1268042.0625	1141498.28125	1218359.70313	874454.125	902928.89063	1159644.53125	1033252.6875	254297.5625
+AAGIEIQK	Q99459	1442119.75	2303356.25	1546983.875	1332364.375	1857631.25	1675623.625	1407504.625	1595244.25
+AAGLATMISTMRPDIDNMDEYVR	O75533	129531.76563	156002.3125	152765.96875	143542.79688	139610.48438	135584.25	134563.5	122802.88281
+AAGLVSDLDADSGLTLSR	Q9BW92	212659.03125	247856.92188	204497.92188	177997.84375	197159.875	199794.96875	166342.04688	213215.32813
+AAGNPGSLAAPIDHKPCSAPLEPK	Q14676	912378.1875	713647.4375	1034114.4375	646169.875	895505.1875	875204.1875	818826.125	600055.9375
+AAGPLLTDECR	Q9BQ69	1104387.75	1081536.125	998458.9375	808628.4375	1026506.3125	1091995.75	958982.5625	853784.75
+AAGPSLSHTSGGTQSK	P27694	3575987.75	4070154.25	5306399.0	1542368.25	3195134.75	2139197.5	4085536.21875	4622196.0
+AAGSPSPLPAPDPAPK	Q9BZE9	139683.90625	186352.4375	175912.79688	103644.70313	164606.95313	157925.0	123462.28906	140471.70313
+AAGSPSSSDQDEKLPGQDESTAGTSEQNDILK	Q9Y520	300375.4375	342935.25	306828.90625	218726.96875	460679.5625	370771.84375	334661.0625	349870.09375
+AAGTCGVLLR	Q5T653	749087.625	724390.875	706781.9375	1178300.25	1026553.5625	797478.4375	1007446.375	867843.9375
+AAGTDGSDFQHR	Q8N5M9	1469103.625	1217041.75	1547335.0	353613.1875	869018.4375	718556.3125	472489.5	1138422.625
+AAGVNVEPFWPGLFAK	P05386	4669496.39063	5185436.9375	4030255.92188	3842251.75	4168020.78125	4271546.53125	4379697.5	3822751.03125
+AAGYELGK	P0A6P9	7163540.5	17434346.0	6790140.5	2699205.75	2847548.0	5858988.5	3711811.25	15878382.0
+AAHLCAEAALR	Q9UQ80	956625.375	861253.0625	757748.25	3475132.25	679888.5625	958009.625	5281153.125	694367.9375
+AAHSEGNTTAGLDMR	P78371	194823.9375	193278.95313	213910.40625	87916.75	143047.60938	146324.57813	194084.125	174745.25
+AAIAYGADEVDVVFPYR	P0A6L0	97584.51563	178866.6875	96728.85938	7255.25	67451.21094	87900.98438	64202.72266	122845.92969
+AAIDWFDGK	P35637, Q92804	5121349.5	5312044.5	5501904.5	4511093.0	4599165.0	4981283.5	4725415.0	4429755.5
+AAIDWFDGKEFHGNIIK	Q92804	1003621.5625	792914.0	736996.6875	683555.875	776416.625	960054.8125	734372.0625	773286.1875
+AAIDWFDGKEFSGNPIK	P35637	1064765.25	1545519.0	1004074.04688	699691.0625	948068.5	865003.3125	948256.9375	1218598.5625
+AAIDWFDGKEFSGNPIKVSFATR	P35637	324202.4375	512002.75	225817.64063	229086.34375	375378.125	395896.71875	267840.0	360976.84375
+AAIDWFDGKEFSGNPIKVSFATRR	P35637	580297.29688	647647.96875	394594.64063000004	174877.65625	384665.25	408326.28125	334656.29688000004	420144.28125
+AAIECEQPQPDLYK	Q8NB49	218861.70313	130997.26563	228506.21875	0.0	113815.08594	103091.69531	132928.6875	173761.40625
+AAIISAEGDSK	P35232	7801684.0	9231531.0	9246344.0	6054634.0	8432891.0	9222132.0	7447091.0	6559744.5
+AAILPTSIFLTNK	O14744	423984.21875	522345.09375	482580.21875	418275.0625	434274.90625	425626.71875	439867.875	379751.09375
+AAILPTSIFLTNKK	O14744	625128.5	643653.375	365402.25	442428.90625	428453.5	494745.6875	427285.65625	601980.0
+AAISQASDVAALDNVR	P08312	333397.40625	1023469.625	790385.4375	199086.64063	241536.25	632406.8125	327662.4375	637685.4375
+AAITAEIR	P02413, P75981	663247.125	1411357.75	599106.9375	440599.28125	591019.9375	688495.8125	552861.375	1358412.375
+AAKPTTTPEVK	P46821	597655.6875	1084973.75	1089056.0	204095.40625	926111.0	521438.625	528026.4375	1050476.375
+AALAAGGEAAK	P76177	385484.75	1195058.125	713882.8125	110224.98438	168155.76563	207413.17188	154176.5	1195812.625
+AALANLCIGDVITAIDGENTSNMTHLEAQNR	O00151	273779.4375	237322.625	177198.78125	215895.39063	181567.95313	235941.07813	166300.9375	232258.26563
+AALANLFSELPSK	P0ADE8	159359.51563	393346.625	59545.30469	71913.36719	63312.11719	74082.35156	41914.84375	277079.125
+AALCGIPTPSLASGLWR	Q6UXF7, Q8NCF0	1941180.0	3981445.0	1159496.625	665633.8125	313715.53125	1491660.0	565038.875	3818637.75
+AALDEAQGVGLDSTGYYDQEIYGGSDSR	O75533	262641.28125	249312.20313	196227.89063	217566.32813	290130.59375	216985.51563	200239.78125	300018.84375
+AALEALGSCLNNK	P34897	4322418.5	5489176.5	6389716.0	4558024.5	4395557.5	6872015.0	4348551.5	3806548.5
+AALEALLPYTER	Q12788	655072.9375	906333.875	792560.375	626749.125	742442.0625	703573.5625	780987.875	683775.6875
+AALEELVK	P12081	2348138.75	2368818.5	2275226.75	1747828.125	2378448.25	2287024.0	2191865.5	2006949.375
+AALEEVYPDLTPEETR	Q9H0D6	692764.375	708531.1875	673618.3125	474416.6875	556246.0625	619913.6875	539989.875	602085.0625
+AALEEVYPDLTPEETRR	Q9H0D6	1211489.125	1504644.375	1281057.125	1205882.0	963158.75	1128693.125	1278474.75	1022331.8125
+AALELAEQR	P0A7V8	3731073.25	8142785.0	2289732.5	1210433.875	608250.0625	2375839.0	1070798.75	6663977.5
+AALESTLAAITESLK	P0ACF0	24043603.0	13105575.75	15771737.0	9224710.75	2732858.3125	15605359.5	7751556.0	36791177.0
+AALETDENLLLCAPTGAGK	O75643	440628.125	469545.3125	318780.46875	271547.09375	450282.34375	430714.96875	317435.875	341934.21875
+AALGPLVTGLYDVQAFK	P11172	239691.32813	140373.0625	210124.70313	190000.15625	169248.41407	168612.48437	227503.375	169537.5625
+AALGVLR	P00961, P22570	990935.4375	1174846.125	928135.375	1347850.0	916877.6875	988464.0	1326013.125	1053958.25
+AALHLYSNTLNFQISEVEPK	P41227	255513.9375	367783.21875	310718.78125	235509.14063	232904.64063	257361.75	275325.75	285266.875
+AALIDCLAPDR	P0A910	13255762.0	17645074.0	9979471.0	9441315.0	9862663.0	12722175.0	10226177.0	13172072.0
+AALLELWELR	Q13813	188631.1875	244107.48438	156031.07813	175344.6875	163521.5	211266.125	155224.98438	166531.54688
+AALLELWELRR	Q13813	184153.35938	383340.1875	186248.29688	214994.3125	245186.17188	282035.53125	219709.57813	280941.0625
+AALLNQHYQVNFK	P07814	1832302.625	2022652.0	2105822.75	1744818.375	2229919.75	2041642.5	2006596.5	1884938.875
+AALMESQGQQQEER	Q14980	279351.09375	279784.90625	268788.84375	169064.17188	264672.96875	280829.96875	191924.53125	195184.04688
+AALNALQPPEFR	Q3ZAQ7	839390.8125	818964.0625	951292.0	660945.6875	862311.1875	801881.5625	770923.375	908567.75
+AALNGADIYAGCCTLK	Q8WVV9	250663.82813	381020.5625	1458328.125	163069.3125	1423089.625	275286.4375	249480.75	705733.0625
+AALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESNFAR	O75390	131756.51563	211718.125	47709.47266	16242.18652	75513.69531	156406.14063	18517.95508	80693.10156
+AALQEEEQASK	O00139	2002426.875	4818946.5	1148327.0	1085537.25	378663.71875	1432699.0	648731.875	3835177.75
+AALQELLSK	P62851	676653.1875	908379.125	582021.0625	441705.40625	635442.3125	579118.875	518931.5	581147.375
+AALRPLVKPK	P62910	14300628.0	14053010.0	14299115.0	7060798.5	12172450.0	13335538.0	10203519.0	11596694.0
+AALSASEGEEVPQDK	O95831	763878.3125	1105662.125	697007.375	885170.3125	720328.625	820067.4375	778948.375	734812.75
+AALSASEGEEVPQDKAPSHVPFLLIGGGTAAFAAAR	O95831	693677.375	703225.125	539571.3125	365880.4375	565751.6875	581676.1875	527478.6875	595952.0
+AALSEEELEK	Q04637	3795494.5	3793492.0	3522114.5	2862942.0	3878220.75	3676267.75	3446547.5	3995276.0
+AALSLPAK	Q14978	2936206.75	2462671.25	2887397.75	2513020.25	2948848.5	2900837.75	2367291.75	2793692.0
+AALTGLLHR	P55084	850884.6875	591027.0625	857093.4375	561125.0	940613.0	927020.875	693871.875	682764.125
+AALVDHDNIK	P0AFH8	8947789.5	22207897.0	7547923.875	3073040.9375	1898858.15625	7392246.125	2802845.75	18122558.0
+AAMDNSEIAGEKK	Q16891	119404.5625	144653.84375	73145.03125	320810.4375	39021.0	123004.38281	99947.88281	98398.91406
+AAMEALVVEVTK	Q08211	436194.375	626586.0	347930.0	270864.71875	328265.1875	351827.28125	337660.71875	401312.71875
+AAMEALVVEVTKQPAIISQLDPVNER	Q08211	472466.96875	353919.60938000004	283896.76563	310880.41407	189122.375	161755.54688	354237.32813000004	349402.85938000004
+AANDDLLNSFWLLDSEK	P68066	16827173.0	5337574.375	7304464.625	4716622.5	1045996.25	10427364.75	4180498.78125	31400458.5
+AANDDLLNSFWLLDSEKGEAR	P68066	7685030.25	1364759.96875	4006690.75	3326748.38354	643351.54468	165379.45313	2252557.75	362244.82813000004
+AANGVVLATEKK	P25787	1680917.25	1465688.875	1730097.375	1477618.0	2058496.875	2011640.625	1531829.5	1718817.0
+AANIIGIQIEFAK	P02413	214227.70313	357106.15625	90620.01563	91168.23438	4882.55029	136230.90625	54517.05469	252177.29688
+AANKFPAIIYGGK	P68919	2215884.5	4982129.0	1605986.375	946958.5	358732.40625	1455951.375	744919.75	4208973.0
+AANNGALPPDLSYIVR	P08574	407361.96875	493226.15625	386954.65625	376689.9375	310397.09375	266972.5625	376921.40625	278980.84375
+AANSLEAFIFETQDK	Q9Y4L1	269493.96875	850941.5625	581885.15625	217460.67188	330248.59375	262135.76563	185038.875	282498.28125
+AAPAPAAAAPK	P69797	1109316.875	3096612.0	706772.125	292695.4375	152983.09375	639140.8125	331854.53125	1819221.5
+AAPATPAAPAQPGLLSR	P21513	409903.59375	201135.5	281988.15625	337116.28125	374257.1875	424250.25	450403.28125	251163.79688
+AAPCIYWLPLTDSQIVQK	Q9UKV3	327136.125	808966.96875	254954.85938	242602.48438	615534.9375	341145.03125	334661.125	397033.9375
+AAPDEDREPESAR	Q99856	431261.0	360969.15625	434003.625	89810.55469	376815.8125	203621.98438	395812.84375	664373.8125
+AAPDILIATPGR	Q96GQ7	1105000.75	1257239.125	1251074.375	880168.0625	1131456.625	1049179.625	1029255.75	1148296.625
+AAPDVQLLMNDSQNDQSK	P0AEE5	151512.1875	281879.5625	107820.57813	137424.79688	124220.39063	35971.01953	201627.09375	253344.42188
+AAPEEPQQRPPEAVAAAPAGTTSSR	Q96JP5	320053.40625	266149.46875	306922.03125	313679.375	236602.29688	384658.25	271009.28125	286426.46875
+AAPFSLEYR	Q15181	4102598.5	5215086.0	4304278.0	3733301.0	4087060.75	4127228.25	4050282.25	4298434.5
+AAPGAEFAPNK	Q15233	14382504.0	14811979.0	12693170.0	12167287.0	15397708.0	15076291.0	15510196.0	13160847.0
+AAPGAEFAPNKR	Q15233	14723716.875	14975034.0	17364607.75	11938107.0625	1774052.0	13810585.0	16457068.875	13324748.375
+AAPLAGFGYGLPISR	Q15120	230245.59375	544393.1875	196838.8125	171844.71875	216407.42188	151602.4375	184503.09375	428014.4375
+AAPLDSIHSLAAYYIDCIR	P49327	363866.65625	636304.375	593693.625	333754.84375	497249.125	558048.0	391743.59375	412834.84375
+AAPRPAPVAQPPAAAPPSAVGSSAAAPR	Q5T1J5, Q9Y6H1	1942448.25	1501632.375	1738653.375	1077041.5	1444507.875	1437091.25	1203017.875	1621369.25
+AAPSYEELSNSQELLETGIK	P0ABB4	739256.875	840175.1875	627793.5	455730.90625	554522.1875	660437.9375	549268.1875	868215.75
+AAPTAASDQPDSAATTEK	Q9BRP8	351295.25	500154.78125	470438.90625	466281.25	416278.03125	424837.375	400243.625	715331.3125
+AAPTPTPAPVPVPVPLPAPAPAPHGEAR	Q96T58	294953.65625	239035.82813	226893.79688	232195.21875	183525.48438	190278.3125	221212.28125	296480.09375
+AAQAGPTQPGPPR	Q9BUL5	145509.75	224699.84375	173154.4375	98017.83594	139799.85938	156054.15625	147445.92188	163769.70313
+AAQAPSSFQLLYDLK	P11586	1337199.875	1737023.0	985316.625	1104542.5	1483559.375	1176894.875	1245059.375	1389066.125
+AAQDLCEEALR	O94906	1025615.8125	1665136.625	918830.8125	705914.3125	777196.375	975519.1875	708376.0625	1298601.125
+AAQDRDQIYR	P62995	8423862.0	10446902.375	7589230.5	16331922.0	8208110.5	6994738.0	9705573.0	8196938.0
+AAQEEEFSLELR	P0ABS1	1019868.125	2825327.75	770933.0625	721486.0625	731734.875	903161.5	752966.875	1660735.125
+AAQEEYVK	P04075	843185.5625	791107.75	1795085.625	408560.15625	1492480.25	898337.25	811546.375	1251913.625
+AAQEEYVKR	P04075	8811726.25	11551333.5	27064740.5	4649580.3125	18564343.5	9248207.25	12678117.125	20363443.0
+AAQEFLESLNFDEIDECVRNIER	Q9HD67	169189.14063	512143.71875	515558.8125	532130.5625	130190.08594	165989.25	418496.3125	495984.75
+AAQELQEGQR	P0DN79, P35520	2502464.0	4255015.5	4808693.5	644340.4375	3002025.0	1687013.625	2157380.5	4736799.0
+AAQLAIR	P62910	20362028.0	47268032.0	15944895.0	6969807.0	8318394.5	16588878.0	7996014.5	43820748.0
+AAQPPAQPCQLCGR	Q96B54	310749.71875	283989.71875	223823.1875	207503.84375	262824.84375	265540.9375	238472.35938	258411.03125
+AAQQQQPSASPR	Q86U86	48489.09766	60418.30469	84443.5625	49943.30469	50419.42578	71356.11719	64746.06641	59020.58984
+AAQVPVVVAVNK	P0A705	690914.4375	1266495.0	320707.15625	212252.75	172041.42188	386872.25	192951.64063	933956.625
+AAQYQVNQAAAAQAAATAAAMTQSAVK	Q9NR56	412374.96875	150320.26563	1812041.375	156913.98438	165427.3125	192793.14063	152438.75	168492.40625
+AAQYVASHPGEVCPAK	P0AE08	15864123.0	51993361.5	12056009.5	6261370.3125	2155603.75	12391275.875	5883448.5625	27818716.5
+AASADSTTEGTPADGFTVLSTK	O75367	1116173.21875	2907101.0	1226918.10938	871459.53125	895058.5625	998934.90625	977392.84375	973814.9375
+AASAGQEPLHNEELAGAGR	Q96HY6	889178.5625	921382.5	883829.1875	797695.9375	1001295.3125	1120548.625	802324.5	935400.125
+AASAYAVGDVK	P13861	1485589.125	1330503.5	1178909.375	1040358.4375	1372300.125	1191166.875	1083942.875	1228998.125
+AASDIWKPVLSIDTEPR	Q96JM3	281060.625	452834.5	279770.71875	321321.59375	328187.25	368099.65625	438101.65625	369116.59375
+AASEEYNWDLNYGEIAK	P00350	283509.875	564879.5625	128560.86719	86421.16406	6532.9013700000005	182205.84375	137571.23438	422277.28125
+AASIFGGAKPVDTAAR	P23588	2394175.5	3604647.0	2289038.75	1917155.5	1449951.875	1644326.75	2111056.0	3053623.0
+AASITSEVFNKFFKER	Q9Y5B9	117960.92188	126077.96875	97117.28125	119717.07813	114889.77344	109439.32813	116697.32031	154608.9375
+AATAAADFTAK	Q9Y3F4	3917802.25	4149708.5	3546833.0	1937551.625	3462372.75	3132683.25	2292475.25	2413771.5
+AATALKDVVK	Q15084	1268887.5	1370430.0	1455083.75	949831.4375	1407677.875	1693036.125	1029028.125	1127469.5
+AATAPLLEAVDNLSAFASNPEFSSIPAQISPEGR	Q9Y490	418117.23438000004	437334.35938000004	116392.84375	91101.60547	67913.22656	156233.71875	124191.64452999999	118919.4375
+AATFGLILDDVSLTHLTFGK	P35232	368993.15625	536513.0	308890.78125	152407.85938	330637.28125	335566.875	150468.8125	288719.875
+AATGEEVSAEDLGGADLHCR	Q9HCC0	713096.3125	1157865.125	886318.4375	660403.0	727666.875	790421.5625	848064.9375	906844.25
+AATILAEQLEAFVDLR	P0A7Z4	463321.625	771793.875	182596.30469	211887.52344000002	104940.16406	98192.11719	112944.75391	340720.84375
+AATITATSPGALWGLDR	P31323	166537.35938	190122.20313	102650.57813	117641.97656	143498.53125	144261.40625	164546.8125	240236.23438
+AATITPFR	Q13423	1266772.5	1144386.625	1263772.75	868970.5625	1182768.5	1272546.75	1157362.625	926989.5
+AATIVATSEGSLWGLDR	P13861	373940.25	315889.96875	255084.46875	216083.85938	231952.28125	307028.03125	198671.39063	329004.09375
+AATLILEPAGR	P49753, Q86TX2	1246324.375	1315777.5	1111768.375	1300046.0	1103887.0	844185.4375	1114889.375	1102775.5
+AATLPHEQR	Q6PD74	327455.625	598046.1875	478179.40625	140029.4375	547710.9375	386615.125	209003.15625	461980.125
+AATQFWR	P13667	2370100.5	2073749.125	1958417.875	1201990.75	1731749.875	1916142.25	1592493.625	2070763.875
+AATSEGVQVK	P51608	258779.26563	818176.1875	803724.625	186500.6875	409854.65625	299316.5	348250.875	941427.9375
+AATTEPTEVEEVVPALEPTETLLSEK	Q9BXK5	254085.875	323606.21875	201949.5625	193788.5	152049.17188	159238.85938	243993.04688	186718.1875
+AAVAFAPGKPLEIVEIDVAPPK	P25437	121347.04688	374993.5625	70694.5625	85127.13281	47131.46484	89174.42969	25806.17578	234406.40625
+AAVATFLQSVQVPEFTPK	P22314	1215883.875	5004095.375	3042419.125	2534024.625	1290454.875	1068574.125	1085994.25	1496532.875
+AAVAWEAGKPLSIEEIEVAPPK	P11766	880564.9375	711888.4375	774589.9375	521704.3125	647899.25	754981.8125	647790.6875	579748.125
+AAVDAGFVPNDMQVGQTGK	P13804	703540.5625	1105543.75	584439.625	434465.15625	492411.6875	521865.0	486507.09375	628963.25
+AAVEEGIVLGGGCALLR	P10809	14604331.75	19574214.5	12754827.5	12971932.75	15320584.25	16180003.5	12196336.0	14062687.75
+AAVEEGVVAGGGVALIR	P0A6F5	996091.4375	4659981.25	975535.3125	1879227.90625	923931.0625	1720385.4375	1201319.78125	2827220.875
+AAVENLPTFLVELSR	Q14974	2339959.1875	2179483.4375	2203616.25	1467668.0	1950778.8125	1955095.75	1355188.625	1972279.5625
+AAVESLGFILFR	Q99460	109935.35938	108358.625	96774.625	104065.46094	111914.89844	107003.10156	94293.25	88740.69531
+AAVETLGVPCFLGGMAR	A1L0T0	122606.89844	189491.1875	177914.67188	113754.82813	156852.95313	180123.42188	144989.23438	142232.23438
+AAVEWFDGK	Q01844	1129111.625	1152426.75	1042474.3125	852575.75	1232521.125	1052781.375	934250.1875	905730.875
+AAVEWFDGKDFQGSK	Q01844	3742938.34375	3327645.75	3208572.09375	3384849.8125	4812751.75	4015413.9375	3720032.5	3545558.53125
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/quantitation.tsv	Tue Oct 02 16:30:33 2018 -0400
@@ -0,0 +1,1130 @@
+protein	comparison	logFC	pvalue	qvalue
+A1L0T0	ecoli_2-ecoli_1	-9.39530454360043e-18	0.9999999967240936	1
+A1L0T0	ecoli_3-ecoli_1	-3.5591253620981224e-17	0.9999999875902251	1
+A1L0T0	ecoli_7-ecoli_1	-2.3165346387522672e-17	0.9999999919228264	1
+A1L0T0	ecoli_3-ecoli_2	-2.6195949077380796e-17	0.9999999908661314	1
+A1L0T0	ecoli_7-ecoli_2	-1.3770041843922244e-17	0.9999999951987328	1
+A1L0T0	ecoli_7-ecoli_3	1.242590723345855e-17	0.9999999956673987	1
+O00139	ecoli_2-ecoli_1	0.0018448291421766516	0.9958340324121795	1
+O00139	ecoli_3-ecoli_1	1.2321715267791753	0.009783597971314853	0.1081950834474819
+O00139	ecoli_7-ecoli_1	0.29765360883577596	0.41270893111828805	1
+O00139	ecoli_3-ecoli_2	1.2303266976369986	0.00985050554661475	0.07870172578796708
+O00139	ecoli_7-ecoli_2	0.2958087796935993	0.41545686820524286	1
+O00139	ecoli_7-ecoli_3	-0.9345179179433993	0.031050234425502816	0.3346874803222741
+O00151	ecoli_2-ecoli_1	0	1	1
+O00151	ecoli_3-ecoli_1	0	1	1
+O00151	ecoli_7-ecoli_1	0	1	1
+O00151	ecoli_3-ecoli_2	0	1	1
+O00151	ecoli_7-ecoli_2	0	1	1
+O00151	ecoli_7-ecoli_3	0	1	1
+O00273	ecoli_2-ecoli_1	5.871639230477629e-20	0.9999999998722429	1
+O00273	ecoli_3-ecoli_1	-1.1315125448089434e-19	0.9999999997538016	1
+O00273	ecoli_7-ecoli_1	-5.478461975713279e-20	0.9999999998807978	1
+O00273	ecoli_3-ecoli_2	-1.718676467856706e-19	0.9999999996260445	1
+O00273	ecoli_7-ecoli_2	-1.1350101206190906e-19	0.9999999997530407	1
+O00273	ecoli_7-ecoli_3	5.836663472376154e-20	0.9999999998730038	1
+O14744	ecoli_2-ecoli_1	0.02828200890204465	0.7153702716813223	1
+O14744	ecoli_3-ecoli_1	-0.04121721312113948	0.5969001328985126	1
+O14744	ecoli_7-ecoli_1	-0.022311914287492247	0.7732304112816045	1
+O14744	ecoli_3-ecoli_2	-0.06949922202318413	0.3803013399754621	0.8826747150047763
+O14744	ecoli_7-ecoli_2	-0.0505939231895369	0.5181380333258057	1
+O14744	ecoli_7-ecoli_3	0.018905298833647236	0.8069642650302242	1
+O15042	ecoli_2-ecoli_1	0.17911599032933245	0.11832659488452864	1
+O15042	ecoli_3-ecoli_1	0.06805502716489177	0.518346003187115	1
+O15042	ecoli_7-ecoli_1	0.044799515505470136	0.6677495724863654	1
+O15042	ecoli_3-ecoli_2	-0.1110609631644407	0.3045359469198265	0.7340097182170177
+O15042	ecoli_7-ecoli_2	-0.13431647482386233	0.22265140329154973	0.9285716951999126
+O15042	ecoli_7-ecoli_3	-0.023255511659421635	0.8227313126557558	1
+O60784	ecoli_2-ecoli_1	-2.3427915799696938e-17	0.9999999954352896	1
+O60784	ecoli_3-ecoli_1	-1.873971440104913e-17	0.9999999963487418	1
+O60784	ecoli_7-ecoli_1	-1.1635183334801913e-17	0.9999999977329933	1
+O60784	ecoli_3-ecoli_2	4.688201398647808e-18	0.9999999990865478	1
+O60784	ecoli_7-ecoli_2	1.1792732464895028e-17	0.9999999977022964	1
+O60784	ecoli_7-ecoli_3	7.10453106624722e-18	0.9999999986157486	1
+O75367	ecoli_2-ecoli_1	0	1	1
+O75367	ecoli_3-ecoli_1	0	1	1
+O75367	ecoli_7-ecoli_1	0	1	1
+O75367	ecoli_3-ecoli_2	0	1	1
+O75367	ecoli_7-ecoli_2	0	1	1
+O75367	ecoli_7-ecoli_3	0	1	1
+O75390	ecoli_2-ecoli_1	0	1	1
+O75390	ecoli_3-ecoli_1	0	1	1
+O75390	ecoli_7-ecoli_1	0	1	1
+O75390	ecoli_3-ecoli_2	0	1	1
+O75390	ecoli_7-ecoli_2	0	1	1
+O75390	ecoli_7-ecoli_3	0	1	1
+O75533	ecoli_2-ecoli_1	0.3169426749019405	0.03935896775592092	1
+O75533	ecoli_3-ecoli_1	-0.11935706151634232	0.36406826123496344	0.9125977748289751
+O75533	ecoli_7-ecoli_1	-0.03610533570198816	0.7767379504279389	1
+O75533	ecoli_3-ecoli_2	-0.4362997364182828	0.010969442439346803	0.07931750686912303
+O75533	ecoli_7-ecoli_2	-0.35304801060392865	0.026376452972486385	0.3541980827733886
+O75533	ecoli_7-ecoli_3	0.08325172581435417	0.5192725751641845	1
+O75643	ecoli_2-ecoli_1	5.317609740520191e-19	0.9999999993619537	1
+O75643	ecoli_3-ecoli_1	-1.6961687453489036e-18	0.9999999979648111	1
+O75643	ecoli_7-ecoli_1	-7.42652156227463e-19	0.9999999991089109	1
+O75643	ecoli_3-ecoli_2	-2.227929719400923e-18	0.9999999973267648	1
+O75643	ecoli_7-ecoli_2	-1.2744131302794821e-18	0.9999999984708647	1
+O75643	ecoli_7-ecoli_3	9.535165891214406e-19	0.9999999988559001	1
+O94826	ecoli_2-ecoli_1	0.17434957181919067	0.17737706443743412	1
+O94826	ecoli_3-ecoli_1	-0.22939359524001673	0.09054145615373821	0.35597409673867186
+O94826	ecoli_7-ecoli_1	0.041563698630037116	0.729030659100311	1
+O94826	ecoli_3-ecoli_2	-0.40374316705920743	0.011708495616390742	0.07990512966638055
+O94826	ecoli_7-ecoli_2	-0.13278587318915355	0.28933832290881495	1
+O94826	ecoli_7-ecoli_3	0.27095729387005385	0.05444355013372875	0.38966496981959714
+O94906	ecoli_2-ecoli_1	-0.002877957436813919	0.9818280610439835	1
+O94906	ecoli_3-ecoli_1	0.3888779382145671	0.017600220557025887	0.13901624882226976
+O94906	ecoli_7-ecoli_1	0.0656978954068384	0.6071911635424636	1
+O94906	ecoli_3-ecoli_2	0.391755895651381	0.017070352801343478	0.09941469785383684
+O94906	ecoli_7-ecoli_2	0.06857585284365232	0.5919086753149504	1
+O94906	ecoli_7-ecoli_3	-0.3231800428077287	0.036116823402158556	0.3346874803222741
+O95831	ecoli_2-ecoli_1	0.0245985326669663	0.7997674961092389	1
+O95831	ecoli_3-ecoli_1	-0.09820206747941315	0.3275525920663132	0.8797126758352412
+O95831	ecoli_7-ecoli_1	-0.07227801164675313	0.4640316114219951	1
+O95831	ecoli_3-ecoli_2	-0.12280060014637945	0.22946339401310026	0.5829610550603087
+O95831	ecoli_7-ecoli_2	-0.09687654431371943	0.3336825703627786	1
+O95831	ecoli_7-ecoli_3	0.025924055832660012	0.7892801024896633	1
+P00350	ecoli_2-ecoli_1	-0.4777664147983703	0.44958084528097886	1
+P00350	ecoli_3-ecoli_1	0.581930291766587	0.36157573562441137	0.9125977748289751
+P00350	ecoli_7-ecoli_1	0.06452981264404109	0.9170206378854528	1
+P00350	ecoli_3-ecoli_2	1.0596967065649572	0.11745233416704542	0.3619842430066318
+P00350	ecoli_7-ecoli_2	0.5422962274424113	0.3934251191950704	1
+P00350	ecoli_7-ecoli_3	-0.5174004791225458	0.41445902597928685	1
+P00961, P22570	ecoli_2-ecoli_1	5.400092721761121e-21	0.9999999999848024	1
+P00961, P22570	ecoli_3-ecoli_1	-2.3704757498732066e-20	0.9999999999332867	1
+P00961, P22570	ecoli_7-ecoli_1	-2.1306213703114063e-20	0.9999999999400371	1
+P00961, P22570	ecoli_3-ecoli_2	-2.910485022049319e-20	0.9999999999180891	1
+P00961, P22570	ecoli_7-ecoli_2	-2.6706306424875185e-20	0.9999999999248393	1
+P00961, P22570	ecoli_7-ecoli_3	2.3985437956180052e-21	0.9999999999932496	1
+P02413	ecoli_2-ecoli_1	-1.5127435505183047e-19	0.9999999999314704	1
+P02413	ecoli_3-ecoli_1	5.796905849079552e-19	0.9999999997373914	1
+P02413	ecoli_7-ecoli_1	2.2797391996958357e-19	0.9999999998967244	1
+P02413	ecoli_3-ecoli_2	7.309649399597857e-19	0.9999999996688618	1
+P02413	ecoli_7-ecoli_2	3.7924827502141405e-19	0.9999999998281948	1
+P02413	ecoli_7-ecoli_3	-3.517166649383716e-19	0.999999999840667	1
+P04075	ecoli_2-ecoli_1	0	1	1
+P04075	ecoli_3-ecoli_1	0	1	1
+P04075	ecoli_7-ecoli_1	0	1	1
+P04075	ecoli_3-ecoli_2	0	1	1
+P04075	ecoli_7-ecoli_2	0	1	1
+P04075	ecoli_7-ecoli_3	0	1	1
+P05091	ecoli_2-ecoli_1	0.011413176435064246	0.9289917033015069	1
+P05091	ecoli_3-ecoli_1	-0.27617246190930644	0.06225431955625532	0.29259530191440003
+P05091	ecoli_7-ecoli_1	-0.1619662609443243	0.23269346676877603	1
+P05091	ecoli_3-ecoli_2	-0.2875856383443707	0.0545002690555956	0.2276900129433772
+P05091	ecoli_7-ecoli_2	-0.17337943737938852	0.20485876002125494	0.8905353073693035
+P05091	ecoli_7-ecoli_3	0.11420620096498216	0.38686158529993253	1
+P05386	ecoli_2-ecoli_1	0.053736872116817186	0.6783047673791209	1
+P05386	ecoli_3-ecoli_1	-0.2492280590698629	0.08645250278874242	0.35332762009312124
+P05386	ecoli_7-ecoli_1	-0.09602235244720372	0.4651356999042514	1
+P05386	ecoli_3-ecoli_2	-0.3029649311866801	0.04630366297677119	0.20244392185192983
+P05386	ecoli_7-ecoli_2	-0.1497592245640209	0.2681548586881306	1
+P05386	ecoli_7-ecoli_3	0.15320570662265917	0.25831146002216976	0.827472304138815
+P06454	ecoli_2-ecoli_1	-1.1228321841946492e-16	0.9999999901218006	1
+P06454	ecoli_3-ecoli_1	-1.683631100604687e-17	0.999999998518813	1
+P06454	ecoli_7-ecoli_1	-5.3384998556761025e-17	0.9999999953034151	1
+P06454	ecoli_3-ecoli_2	9.544690741341806e-17	0.9999999916029876	1
+P06454	ecoli_7-ecoli_2	5.88982198627039e-17	0.9999999948183854	1
+P06454	ecoli_7-ecoli_3	-3.6548687550714154e-17	0.999999996784602	1
+P06753	ecoli_2-ecoli_1	0.030764238397642828	0.7692670590403783	1
+P06753	ecoli_3-ecoli_1	-0.11951301496792001	0.273952041176718	0.8112564488214594
+P06753	ecoli_7-ecoli_1	-0.009085565242102123	0.9307696365821019	1
+P06753	ecoli_3-ecoli_2	-0.15027725336556283	0.17877869255211773	0.4894184628313271
+P06753	ecoli_7-ecoli_2	-0.039849803639744955	0.7045624992700769	1
+P06753	ecoli_7-ecoli_3	0.11042744972581789	0.3091735785494371	0.9579312515712068
+P07813	ecoli_2-ecoli_1	0.2372026226229671	0.5357974877426259	1
+P07813	ecoli_3-ecoli_1	4.079746187782321	3.544612141574623e-5	0.006663870826160292
+P07813	ecoli_7-ecoli_1	-0.8802967437092978	0.051682618005187614	1
+P07813	ecoli_3-ecoli_2	3.842543565159354	4.9510118300063056e-5	0.004653951120205928
+P07813	ecoli_7-ecoli_2	-1.117499366332265	0.022031646374075873	0.3541980827733886
+P07813	ecoli_7-ecoli_3	-4.9600429314916195	1.180266732530396e-5	0.0022307041244824482
+P07814	ecoli_2-ecoli_1	0.12053228429934824	0.427736966073307	1
+P07814	ecoli_3-ecoli_1	-0.3491030605145049	0.04702260889408572	0.23919768442343972
+P07814	ecoli_7-ecoli_1	-0.14395223428589754	0.3486345091227212	1
+P07814	ecoli_3-ecoli_2	-0.46963534481385316	0.014873632432230164	0.09642216887100934
+P07814	ecoli_7-ecoli_2	-0.2644845185852458	0.10938724514552361	0.6426500652299513
+P07814	ecoli_7-ecoli_3	0.20515082622860736	0.19658463485981414	0.7010282261982052
+P07954	ecoli_2-ecoli_1	1.3578020624933786e-22	0.9999999999994804	1
+P07954	ecoli_3-ecoli_1	5.550525730112217e-23	0.9999999999997876	1
+P07954	ecoli_7-ecoli_1	4.0178476379979607e-23	0.9999999999998462	1
+P07954	ecoli_3-ecoli_2	-8.02749489482157e-23	0.9999999999996928	1
+P07954	ecoli_7-ecoli_2	-9.560172986935827e-23	0.9999999999996342	1
+P07954	ecoli_7-ecoli_3	-1.532678092114256e-23	0.9999999999999414	1
+P08312	ecoli_2-ecoli_1	-0.4394716448398446	0.2474016902991572	1
+P08312	ecoli_3-ecoli_1	0.23073988934796155	0.5293527509484754	1
+P08312	ecoli_7-ecoli_1	0.021428843678297428	0.9527442129239073	1
+P08312	ecoli_3-ecoli_2	0.6702115341878061	0.09512026362106919	0.3083208544958794
+P08312	ecoli_7-ecoli_2	0.460900488518142	0.22720371265529773	0.9285716951999126
+P08312	ecoli_7-ecoli_3	-0.20931104566966413	0.5673092352486693	1
+P08559	ecoli_2-ecoli_1	0.27819571954397754	0.07909668879162723	1
+P08559	ecoli_3-ecoli_1	-0.020082641712841312	0.885837186923053	1
+P08559	ecoli_7-ecoli_1	0.00793522705323247	0.95472943746152	1
+P08559	ecoli_3-ecoli_2	-0.29827836125681884	0.0636576342002103	0.2546305368008412
+P08559	ecoli_7-ecoli_2	-0.2702604924907451	0.08618450641372631	0.63197938142333
+P08559	ecoli_7-ecoli_3	0.028017868766073782	0.8413624823038703	1
+P08574	ecoli_2-ecoli_1	0	1	1
+P08574	ecoli_3-ecoli_1	0	1	1
+P08574	ecoli_7-ecoli_1	0	1	1
+P08574	ecoli_3-ecoli_2	0	1	1
+P08574	ecoli_7-ecoli_2	0	1	1
+P08574	ecoli_7-ecoli_3	0	1	1
+P0A6F5	ecoli_2-ecoli_1	0.07172120898327407	0.8127981238931172	1
+P0A6F5	ecoli_3-ecoli_1	0.7976298281343743	0.03162563888936624	0.19179419713551138
+P0A6F5	ecoli_7-ecoli_1	-0.5816336487388689	0.08955762368298222	1
+P0A6F5	ecoli_3-ecoli_2	0.7259086191511003	0.04447339730466057	0.19907139745895686
+P0A6F5	ecoli_7-ecoli_2	-0.653354857722143	0.06313705332691727	0.5652269535933546
+P0A6F5	ecoli_7-ecoli_3	-1.3792634768732432	0.002723153307611922	0.07352513930552189
+P0A6L0	ecoli_2-ecoli_1	-1.128890324624692e-15	0.9999999756545496	1
+P0A6L0	ecoli_3-ecoli_1	2.808339883481543e-15	0.9999999394358354	1
+P0A6L0	ecoli_7-ecoli_1	1.177954948735006e-15	0.9999999745964305	1
+P0A6L0	ecoli_3-ecoli_2	3.9372302081062355e-15	0.9999999150903849	1
+P0A6L0	ecoli_7-ecoli_2	2.306845273359698e-15	0.99999995025098	1
+P0A6L0	ecoli_7-ecoli_3	-1.6303849347465372e-15	0.9999999648394049	1
+P0A6P9	ecoli_2-ecoli_1	-0.6397452813193203	0.006480010453258999	1
+P0A6P9	ecoli_3-ecoli_1	1.3632149179429331	1.2994478866425288e-4	0.012214810134439771
+P0A6P9	ecoli_7-ecoli_1	0.3628009789777882	0.059507214278955806	1
+P0A6P9	ecoli_3-ecoli_2	2.0029601992622537	1.4556306532762226e-5	0.0027365856281592986
+P0A6P9	ecoli_7-ecoli_2	1.0025462602971085	6.937222217360124e-4	0.13041977768637034
+P0A6P9	ecoli_7-ecoli_3	-1.000413938965145	7.0159005728607e-4	0.04420017360902241
+P0A6Y8	ecoli_2-ecoli_1	0.010446266892863362	0.9370492737982021	1
+P0A6Y8	ecoli_3-ecoli_1	-0.22449565088625906	0.12168429848431493	0.46687036969492257
+P0A6Y8	ecoli_7-ecoli_1	-0.0911472986060722	0.49812407843205864	1
+P0A6Y8	ecoli_3-ecoli_2	-0.2349419177791224	0.10791395604879575	0.33813039561956004
+P0A6Y8	ecoli_7-ecoli_2	-0.10159356549893556	0.4520315302896627	1
+P0A6Y8	ecoli_7-ecoli_3	0.13334835228018685	0.33063708072376463	1
+P0A705	ecoli_2-ecoli_1	-0.2776073627249899	0.5066907187774404	1
+P0A705	ecoli_3-ecoli_1	1.353603982580575	0.013025514846200445	0.12243983955428418
+P0A705	ecoli_7-ecoli_1	0.5455205883564509	0.2137914521544211	1
+P0A705	ecoli_3-ecoli_2	1.631211345305565	0.005566068896419054	0.05680098562596089
+P0A705	ecoli_7-ecoli_2	0.8231279510814408	0.079931954835758	0.6261336462134377
+P0A705	ecoli_7-ecoli_3	-0.8080833942241241	0.08434802243138385	0.43897455293348076
+P0A7J3	ecoli_2-ecoli_1	-0.40260181357523495	0.21522525216564958	1
+P0A7J3	ecoli_3-ecoli_1	0.7343489507252339	0.04351036921904897	0.23919768442343972
+P0A7J3	ecoli_7-ecoli_1	-0.032962376897683235	0.9138082908809273	1
+P0A7J3	ecoli_3-ecoli_2	1.1369507643004688	0.007145522013016109	0.06396943516414422
+P0A7J3	ecoli_7-ecoli_2	0.3696394366775517	0.2507489039862672	0.9662502439995886
+P0A7J3	ecoli_7-ecoli_3	-0.7673113276229171	0.03718749781358601	0.3346874803222741
+P0A7V8	ecoli_2-ecoli_1	-0.4551390189734907	0.2565303162295177	1
+P0A7V8	ecoli_3-ecoli_1	1.4562823736775312	0.006728592940907021	0.08025252987765204
+P0A7V8	ecoli_7-ecoli_1	0.47742012063006417	0.23638743057182635	1
+P0A7V8	ecoli_3-ecoli_2	1.9114213926510217	0.0017638342835875273	0.027371442899113155
+P0A7V8	ecoli_7-ecoli_2	0.9325591396035549	0.04178221531229738	0.4620621458065828
+P0A7V8	ecoli_7-ecoli_3	-0.978862253047467	0.035148296318077	0.3346874803222741
+P0A7Z4	ecoli_2-ecoli_1	0.4268318387095561	0.4162693984035334	1
+P0A7Z4	ecoli_3-ecoli_1	1.192574893096724	0.0469060955460424	0.23919768442343972
+P0A7Z4	ecoli_7-ecoli_1	0.8319672096439363	0.13643857368154097	1
+P0A7Z4	ecoli_3-ecoli_2	0.7657430543871678	0.165433018844041	0.4712334476163592
+P0A7Z4	ecoli_7-ecoli_2	0.40513537093438023	0.43923933816339766	1
+P0A7Z4	ecoli_7-ecoli_3	-0.3606076834527876	0.48913043083678	1
+P0A8T7	ecoli_2-ecoli_1	0.014062646577311932	0.9795720057246751	1
+P0A8T7	ecoli_3-ecoli_1	1.0370554306929216	0.09088700342263963	0.35597409673867186
+P0A8T7	ecoli_7-ecoli_1	0.07755360254357391	0.8877837234304259	1
+P0A8T7	ecoli_3-ecoli_2	1.0229927841156097	0.09452309054247585	0.3083208544958794
+P0A8T7	ecoli_7-ecoli_2	0.06349095596626197	0.9080088350192859	1
+P0A8T7	ecoli_7-ecoli_3	-0.9595018281493477	0.11277792641579794	0.4810629649021967
+P0A910	ecoli_2-ecoli_1	0	1	1
+P0A910	ecoli_3-ecoli_1	0	1	1
+P0A910	ecoli_7-ecoli_1	0	1	1
+P0A910	ecoli_3-ecoli_2	0	1	1
+P0A910	ecoli_7-ecoli_2	0	1	1
+P0A910	ecoli_7-ecoli_3	0	1	1
+P0ABB4	ecoli_2-ecoli_1	-2.0067131029240672e-15	0.9999999202780272	1
+P0ABB4	ecoli_3-ecoli_1	5.810536287888249e-16	0.9999999769161114	1
+P0ABB4	ecoli_7-ecoli_1	5.628256791736849e-16	0.9999999776402648	1
+P0ABB4	ecoli_3-ecoli_2	2.587766731712892e-15	0.9999998971941386	1
+P0ABB4	ecoli_7-ecoli_2	2.569538782097752e-15	0.999999897918292	1
+P0ABB4	ecoli_7-ecoli_3	-1.8227949615139985e-17	0.9999999992758466	1
+P0ABE2	ecoli_2-ecoli_1	-0.24793495189851011	0.5054677884151821	1
+P0ABE2	ecoli_3-ecoli_1	0.44717395264957727	0.22008112149189282	0.7388437650084974
+P0ABE2	ecoli_7-ecoli_1	0.11265796863678174	0.7390590760608566	1
+P0ABE2	ecoli_3-ecoli_2	0.6951089045480874	0.08069730188903677	0.27583805009343476
+P0ABE2	ecoli_7-ecoli_2	0.36059292053529185	0.31015422294783923	1
+P0ABE2	ecoli_7-ecoli_3	-0.33451598401279553	0.2947172242219663	0.9283592562991938
+P0ABS1	ecoli_2-ecoli_1	3.3604649899848793e-4	0.9985955339814282	1
+P0ABS1	ecoli_3-ecoli_1	0.8358588691835234	0.0036001095537593554	0.0564017163422299
+P0ABS1	ecoli_7-ecoli_1	-0.023911487566855155	0.9003927016357729	1
+P0ABS1	ecoli_3-ecoli_2	0.8355228226845249	0.0036072384713708213	0.048440059472693885
+P0ABS1	ecoli_7-ecoli_2	-0.024247534065853643	0.8990022205713011	1
+P0ABS1	ecoli_7-ecoli_3	-0.8597703567503785	0.0031312515045948297	0.07397581679605285
+P0ACF0	ecoli_2-ecoli_1	-4.089644028783471e-20	0.999999999971146	1
+P0ACF0	ecoli_3-ecoli_1	4.9328245049565106e-20	0.999999999965197	1
+P0ACF0	ecoli_7-ecoli_1	6.678473832433215e-20	0.9999999999528808	1
+P0ACF0	ecoli_3-ecoli_2	9.022468533739981e-20	0.9999999999363429	1
+P0ACF0	ecoli_7-ecoli_2	1.0768117861216685e-19	0.9999999999240268	1
+P0ACF0	ecoli_7-ecoli_3	1.745649327476704e-20	0.9999999999876837	1
+P0ADE8	ecoli_2-ecoli_1	0.39365087405649857	0.3703018663623666	1
+P0ADE8	ecoli_3-ecoli_1	1.8832216944827607	0.003319174213002223	0.0564017163422299
+P0ADE8	ecoli_7-ecoli_1	0.6772549203132548	0.14605600562537666	1
+P0ADE8	ecoli_3-ecoli_2	1.489570820426262	0.010047028823995798	0.07870172578796708
+P0ADE8	ecoli_7-ecoli_2	0.2836040462567562	0.5117891910441578	1
+P0ADE8	ecoli_7-ecoli_3	-1.205966774169506	0.0243508673003319	0.32873670855448067
+P0AE08	ecoli_2-ecoli_1	-0.41004515870387526	0.37380141381569126	1
+P0AE08	ecoli_3-ecoli_1	1.3385455875682537	0.0189856292163143	0.14277193170668354
+P0AE08	ecoli_7-ecoli_1	0.4087329433487947	0.3752358667117934	1
+P0AE08	ecoli_3-ecoli_2	1.748590746272129	0.005740525143049239	0.05680098562596089
+P0AE08	ecoli_7-ecoli_2	0.81877810205267	0.10195310450223499	0.6389061215473393
+P0AE08	ecoli_7-ecoli_3	-0.929812644219459	0.07058687125223888	0.40210624801165656
+P0AEE5	ecoli_2-ecoli_1	2.2378089574830433e-20	0.9999999999802648	1
+P0AEE5	ecoli_3-ecoli_1	7.954963159990891e-20	0.9999999999298452	1
+P0AEE5	ecoli_7-ecoli_1	-1.8889096014495172e-20	0.9999999999833418	1
+P0AEE5	ecoli_3-ecoli_2	5.717154202507848e-20	0.9999999999495806	1
+P0AEE5	ecoli_7-ecoli_2	-4.12671855893256e-20	0.9999999999636064	1
+P0AEE5	ecoli_7-ecoli_3	-9.843872761440408e-20	0.999999999913187	1
+P0AES9	ecoli_2-ecoli_1	-0.7684364129453012	0.2556416380753555	1
+P0AES9	ecoli_3-ecoli_1	1.5956232750590744	0.03883310715168509	0.22814450451614987
+P0AES9	ecoli_7-ecoli_1	0.47131342585573555	0.47113149233491536	1
+P0AES9	ecoli_3-ecoli_2	2.3640596880043754	0.007591577300200818	0.06487347874717062
+P0AES9	ecoli_7-ecoli_2	1.2397498388010368	0.08774395648780897	0.63197938142333
+P0AES9	ecoli_7-ecoli_3	-1.1243098492033388	0.11453880116718969	0.4810629649021967
+P0AFH8	ecoli_2-ecoli_1	-0.7985202767891957	0.01163997211998907	1
+P0AFH8	ecoli_3-ecoli_1	1.235049478976554	0.001453235262992271	0.045534704907091154
+P0AFH8	ecoli_7-ecoli_1	0.22794725632821536	0.3469215454709561	1
+P0AFH8	ecoli_3-ecoli_2	2.0335697557657495	9.605006497199952e-5	0.006019137404911969
+P0AFH8	ecoli_7-ecoli_2	1.0264675331174111	0.0036708420831749536	0.17252957790922283
+P0AFH8	ecoli_7-ecoli_3	-1.0071022226483386	0.0040247129596145065	0.08451897215190464
+P0DMV8, P0DMV9	ecoli_2-ecoli_1	0.11203390195656374	0.3547656064135441	1
+P0DMV8, P0DMV9	ecoli_3-ecoli_1	0.07032663121477964	0.5528827312682907	1
+P0DMV8, P0DMV9	ecoli_7-ecoli_1	-0.19302763263276362	0.13346561207899982	1
+P0DMV8, P0DMV9	ecoli_3-ecoli_2	-0.0417072707417841	0.7223641032784058	1
+P0DMV8, P0DMV9	ecoli_7-ecoli_2	-0.3050615345893274	0.032730292754420784	0.3845809398644442
+P0DMV8, P0DMV9	ecoli_7-ecoli_3	-0.26335426384754324	0.0549199163371715	0.38966496981959714
+P0DN79, P35520	ecoli_2-ecoli_1	1.3185100439131234e-18	0.9999999994995394	1
+P0DN79, P35520	ecoli_3-ecoli_1	7.759966952577495e-18	0.9999999970545864	1
+P0DN79, P35520	ecoli_7-ecoli_1	6.570068969119878e-18	0.9999999975062304	1
+P0DN79, P35520	ecoli_3-ecoli_2	6.441456908664371e-18	0.999999997555047	1
+P0DN79, P35520	ecoli_7-ecoli_2	5.251558925206755e-18	0.9999999980066909	1
+P0DN79, P35520	ecoli_7-ecoli_3	-1.1898979834576164e-18	0.9999999995483562	1
+P10809	ecoli_2-ecoli_1	0.14892003195701303	0.2477175359502992	1
+P10809	ecoli_3-ecoli_1	-0.09484185918155355	0.44738107650928416	1
+P10809	ecoli_7-ecoli_1	-0.13657941040612798	0.28517105485353955	1
+P10809	ecoli_3-ecoli_2	-0.24376189113856658	0.07917650933327834	0.2756515510121542
+P10809	ecoli_7-ecoli_2	-0.285499442363141	0.04760532353913416	0.4710421487030117
+P10809	ecoli_7-ecoli_3	-0.04173755122457441	0.7332944099341776	1
+P11172	ecoli_2-ecoli_1	0.028476722979062417	0.8969691643859677	1
+P11172	ecoli_3-ecoli_1	-0.31172923224499083	0.18366383000950393	0.6640153854189758
+P11172	ecoli_7-ecoli_1	0.03343932189768808	0.8791691158474961	1
+P11172	ecoli_3-ecoli_2	-0.3402059552240533	0.15121890617078557	0.4512564184144077
+P11172	ecoli_7-ecoli_2	0.00496259891862566	0.9819857965390291	1
+P11172	ecoli_7-ecoli_3	0.3451685541426789	0.1461344015717775	0.575404206188874
+P11586	ecoli_2-ecoli_1	2.67673276024919e-18	0.9999999983246232	1
+P11586	ecoli_3-ecoli_1	-1.1243681839330962e-17	0.9999999929625384	1
+P11586	ecoli_7-ecoli_1	-6.7310593227027505e-18	0.9999999957870054	1
+P11586	ecoli_3-ecoli_2	-1.3920414599580154e-17	0.9999999912871615	1
+P11586	ecoli_7-ecoli_2	-9.40779208295194e-18	0.9999999941116284	1
+P11586	ecoli_7-ecoli_3	4.512622516628212e-18	0.9999999971755331	1
+P11766	ecoli_2-ecoli_1	-0.0820489957612866	0.4852515047680793	1
+P11766	ecoli_3-ecoli_1	-0.48445346392023664	0.004676672387222024	0.0676318775998262
+P11766	ecoli_7-ecoli_1	0.10717009038676212	0.36901511967639195	1
+P11766	ecoli_3-ecoli_2	-0.40240446815895003	0.010848086806296018	0.07931750686912303
+P11766	ecoli_7-ecoli_2	0.18921908614804872	0.1374038805229043	0.7380551296658859
+P11766	ecoli_7-ecoli_3	0.5916235543069988	0.0017564217643907544	0.06238772174233911
+P12081	ecoli_2-ecoli_1	0.012539228141992848	0.9177234726165111	1
+P12081	ecoli_3-ecoli_1	-0.3591866791327055	0.020676289594730498	0.14396823865960495
+P12081	ecoli_7-ecoli_1	-0.06435825747437338	0.6001425715213731	1
+P12081	ecoli_3-ecoli_2	-0.37172590727469834	0.01797925386718326	0.09941469785383684
+P12081	ecoli_7-ecoli_2	-0.07689748561636622	0.5331214408455948	1
+P12081	ecoli_7-ecoli_3	0.2948284216583321	0.04339950319814907	0.35775398836114275
+P12270	ecoli_2-ecoli_1	0.004021322454170667	0.9833949672083815	1
+P12270	ecoli_3-ecoli_1	-0.6021084470042722	0.015985107909955228	0.13901624882226976
+P12270	ecoli_7-ecoli_1	-0.26209589778552933	0.2048986198494553	1
+P12270	ecoli_3-ecoli_2	-0.6061297694584429	0.01553711245703894	0.09706914037958324
+P12270	ecoli_7-ecoli_2	-0.26611722023969997	0.19887536978914291	0.8905353073693035
+P12270	ecoli_7-ecoli_3	0.34001254921874297	0.11368691601418646	0.4810629649021967
+P13667	ecoli_2-ecoli_1	-3.43636957610988e-23	0.9999999999998552	1
+P13667	ecoli_3-ecoli_1	-8.561234812787174e-23	0.9999999999996393	1
+P13667	ecoli_7-ecoli_1	2.04911594396969e-22	0.9999999999991367	1
+P13667	ecoli_3-ecoli_2	-5.1248652366772943e-23	0.9999999999997841	1
+P13667	ecoli_7-ecoli_2	2.3927529015806777e-22	0.9999999999989919	1
+P13667	ecoli_7-ecoli_3	2.905239425248407e-22	0.9999999999987759	1
+P13804	ecoli_2-ecoli_1	3.402848055486131e-20	0.9999999998871689	1
+P13804	ecoli_3-ecoli_1	1.326483693082478e-19	0.9999999995601665	1
+P13804	ecoli_7-ecoli_1	1.5726412288418334e-19	0.9999999994785459	1
+P13804	ecoli_3-ecoli_2	9.861988875338652e-20	0.9999999996729976	1
+P13804	ecoli_7-ecoli_2	1.2323564232932205e-19	0.9999999995913771	1
+P13804	ecoli_7-ecoli_3	2.461575357593553e-20	0.9999999999183795	1
+P13861	ecoli_2-ecoli_1	7.898156688176108e-15	0.9999998305798139	1
+P13861	ecoli_3-ecoli_1	-3.255392822691321e-15	0.9999999301698763	1
+P13861	ecoli_7-ecoli_1	5.594803178204473e-15	0.9999998799881247	1
+P13861	ecoli_3-ecoli_2	-1.1153549510867428e-14	0.9999997607496902	1
+P13861	ecoli_7-ecoli_2	-2.3033535099716338e-15	0.9999999505916892	1
+P13861	ecoli_7-ecoli_3	8.850196000895795e-15	0.9999998101580011	1
+P15639	ecoli_2-ecoli_1	-0.031479277614269024	0.783611645488742	1
+P15639	ecoli_3-ecoli_1	-0.2723511049861437	0.046058914464484756	0.23919768442343972
+P15639	ecoli_7-ecoli_1	-0.20949970260314466	0.10289644559377321	1
+P15639	ecoli_3-ecoli_2	-0.24087182737187465	0.06876479384099564	0.2693287758772329
+P15639	ecoli_7-ecoli_2	-0.17802042498887563	0.15395088652984723	0.80396574076698
+P15639	ecoli_7-ecoli_3	0.06285140238299902	0.5870076883219976	1
+P17858	ecoli_2-ecoli_1	-0.011553741218472635	0.9236488350094014	1
+P17858	ecoli_3-ecoli_1	-0.2839105905814028	0.04707614001950676	0.23919768442343972
+P17858	ecoli_7-ecoli_1	-0.1122855810961231	0.3677178012449065	1
+P17858	ecoli_3-ecoli_2	-0.27235684936293014	0.054193578178274394	0.2276900129433772
+P17858	ecoli_7-ecoli_2	-0.10073183987765047	0.41610895234339174	1
+P17858	ecoli_7-ecoli_3	0.1716250094852797	0.18591242554612428	0.6889695770238724
+P19404	ecoli_2-ecoli_1	1.157404916204588e-15	0.9999999638355357	1
+P19404	ecoli_3-ecoli_1	2.291017654815219e-15	0.9999999284144856	1
+P19404	ecoli_7-ecoli_1	-1.3920871609645525e-15	0.9999999565026156	1
+P19404	ecoli_3-ecoli_2	1.1336127386106311e-15	0.9999999645789499	1
+P19404	ecoli_7-ecoli_2	-2.5494920771691407e-15	0.9999999203381512	1
+P19404	ecoli_7-ecoli_3	-3.683104815779772e-15	0.9999998849171011	1
+P19623	ecoli_2-ecoli_1	1.3744010007220052e-15	0.9999999555067309	1
+P19623	ecoli_3-ecoli_1	-1.4979638792872723e-15	0.9999999515066491	1
+P19623	ecoli_7-ecoli_1	-2.42505871548916e-15	0.9999999214939526	1
+P19623	ecoli_3-ecoli_2	-2.8723648800092777e-15	0.99999990701338	1
+P19623	ecoli_7-ecoli_2	-3.7994597162111654e-15	0.9999998770006835	1
+P19623	ecoli_7-ecoli_3	-9.270948362018873e-16	0.9999999699873036	1
+P20810	ecoli_2-ecoli_1	4.979846226055637e-4	0.954237347022246	1
+P20810	ecoli_3-ecoli_1	4.7716814172843957e-4	0.9561479758031447	1
+P20810	ecoli_7-ecoli_1	-8.031402784064562e-5	0.9926148424990402	1
+P20810	ecoli_3-ecoli_2	-2.0816480877124143e-5	0.998085821329951	1
+P20810	ecoli_7-ecoli_2	-5.782986504462094e-4	0.9468687840426371	1
+P20810	ecoli_7-ecoli_3	-5.574821695690851e-4	0.9487781483607627	1
+P20962	ecoli_2-ecoli_1	-0.005005308087043678	0.9775431473629096	1
+P20962	ecoli_3-ecoli_1	-0.15070876795749993	0.4072277440518852	0.9942703361266808
+P20962	ecoli_7-ecoli_1	-0.07261825473266076	0.6845792416709587	1
+P20962	ecoli_3-ecoli_2	-0.14570345987045624	0.42232641313336594	0.9413246740343568
+P20962	ecoli_7-ecoli_2	-0.06761294664561708	0.70506599029704	1
+P20962	ecoli_7-ecoli_3	0.07809051322483916	0.6624946902265256	1
+P21513	ecoli_2-ecoli_1	-0.10295150042926621	0.6737426846147434	1
+P21513	ecoli_3-ecoli_1	-1.1005463981889403	0.002943283185072629	0.0564017163422299
+P21513	ecoli_7-ecoli_1	-0.4364219948226654	0.10858903615120001	1
+P21513	ecoli_3-ecoli_2	-0.997594897759674	0.004777983287653589	0.05680098562596089
+P21513	ecoli_7-ecoli_2	-0.3334704943933992	0.20082944834076663	0.8905353073693035
+P21513	ecoli_7-ecoli_3	0.6641244033662748	0.028045565734693367	0.3346874803222741
+P22314	ecoli_2-ecoli_1	1.0326868135778826e-19	0.9999999999086999	1
+P22314	ecoli_3-ecoli_1	9.724538620919886e-20	0.9999999999140251	1
+P22314	ecoli_7-ecoli_1	8.129529451799141e-20	0.9999999999281266	1
+P22314	ecoli_3-ecoli_2	-6.0232951485894066e-21	0.9999999999946748	1
+P22314	ecoli_7-ecoli_2	-2.197338683979687e-20	0.9999999999805733	1
+P22314	ecoli_7-ecoli_3	-1.5950091691207464e-20	0.9999999999858985	1
+P23588	ecoli_2-ecoli_1	5.415145841585816e-16	0.9999999881918258	1
+P23588	ecoli_3-ecoli_1	8.021266652033984e-15	0.9999998250896347	1
+P23588	ecoli_7-ecoli_1	1.8571873432759332e-15	0.9999999595024912	1
+P23588	ecoli_3-ecoli_2	7.479752067875402e-15	0.9999998368978089	1
+P23588	ecoli_7-ecoli_2	1.3156727591173517e-15	0.9999999713106653	1
+P23588	ecoli_7-ecoli_3	-6.1640793087580504e-15	0.9999998655871435	1
+P25437	ecoli_2-ecoli_1	0.1954841184544952	0.6829978949801261	1
+P25437	ecoli_3-ecoli_1	1.3580752495238593	0.02230287831747605	0.14974789727448207
+P25437	ecoli_7-ecoli_1	0.29933969747176825	0.5353446960763781	1
+P25437	ecoli_3-ecoli_2	1.1625911310693642	0.04053425104632415	0.18586437065143757
+P25437	ecoli_7-ecoli_2	0.10385557901727302	0.827427562773139	1
+P25437	ecoli_7-ecoli_3	-1.0587355520520911	0.056058426442105645	0.38966496981959714
+P25738	ecoli_2-ecoli_1	-0.20953035444183737	0.555348529280068	1
+P25738	ecoli_3-ecoli_1	1.5575600018452576	0.003345513074363498	0.0564017163422299
+P25738	ecoli_7-ecoli_1	0.4571594785089802	0.22146592745628435	1
+P25738	ecoli_3-ecoli_2	1.767090356287095	0.001768200232054382	0.027371442899113155
+P25738	ecoli_7-ecoli_2	0.6666898329508175	0.09336663043804111	0.63197938142333
+P25738	ecoli_7-ecoli_3	-1.1004005233362772	0.016360716732688612	0.2576812885398456
+P25787	ecoli_2-ecoli_1	0.07331136275137992	0.6062346905813001	1
+P25787	ecoli_3-ecoli_1	-0.21494487006096255	0.15755479550948384	0.5807902265839796
+P25787	ecoli_7-ecoli_1	-0.11593565147039078	0.42171912469484985	1
+P25787	ecoli_3-ecoli_2	-0.28825623281234247	0.07142742001113836	0.26964859225496696
+P25787	ecoli_7-ecoli_2	-0.1892470142217707	0.20620760645029193	0.8905353073693035
+P25787	ecoli_7-ecoli_3	0.09900921859057177	0.489834136993045	1
+P26641	ecoli_2-ecoli_1	1.2113764684270086e-21	0.9999999999966709	1
+P26641	ecoli_3-ecoli_1	-6.90683979018106e-21	0.999999999981019	1
+P26641	ecoli_7-ecoli_1	9.210457525185482e-22	0.9999999999974688	1
+P26641	ecoli_3-ecoli_2	-8.118216258608069e-21	0.9999999999776898	1
+P26641	ecoli_7-ecoli_2	-2.903307159084603e-22	0.9999999999992022	1
+P26641	ecoli_7-ecoli_3	7.827885542699609e-21	0.9999999999784879	1
+P27694	ecoli_2-ecoli_1	-1.1344807385957294e-21	0.999999999998636	1
+P27694	ecoli_3-ecoli_1	9.980665353838532e-22	0.9999999999988001	1
+P27694	ecoli_7-ecoli_1	2.3411926943546556e-21	0.9999999999971851	1
+P27694	ecoli_3-ecoli_2	2.1325472739795826e-21	0.999999999997436	1
+P27694	ecoli_7-ecoli_2	3.4756734329503854e-21	0.9999999999958211	1
+P27694	ecoli_7-ecoli_3	1.3431261589708024e-21	0.9999999999983851	1
+P27708	ecoli_2-ecoli_1	2.723582318697985e-23	0.9999999999999301	1
+P27708	ecoli_3-ecoli_1	-2.1343461608153435e-22	0.9999999999994515	1
+P27708	ecoli_7-ecoli_1	1.1359917653900819e-22	0.999999999999708	1
+P27708	ecoli_3-ecoli_2	-2.406704392685142e-22	0.9999999999993815	1
+P27708	ecoli_7-ecoli_2	8.636335335202834e-23	0.9999999999997781	1
+P27708	ecoli_7-ecoli_3	3.270337926205426e-22	0.9999999999991596	1
+P28838	ecoli_2-ecoli_1	0	1	1
+P28838	ecoli_3-ecoli_1	0	1	1
+P28838	ecoli_7-ecoli_1	0	1	1
+P28838	ecoli_3-ecoli_2	0	1	1
+P28838	ecoli_7-ecoli_2	0	1	1
+P28838	ecoli_7-ecoli_3	0	1	1
+P29966	ecoli_2-ecoli_1	0	1	1
+P29966	ecoli_3-ecoli_1	0	1	1
+P29966	ecoli_7-ecoli_1	0	1	1
+P29966	ecoli_3-ecoli_2	0	1	1
+P29966	ecoli_7-ecoli_2	0	1	1
+P29966	ecoli_7-ecoli_3	0	1	1
+P31040	ecoli_2-ecoli_1	0.30652184491353485	0.03458989437332217	1
+P31040	ecoli_3-ecoli_1	-0.5900214521260381	0.001967924762142547	0.05285283646897126
+P31040	ecoli_7-ecoli_1	0.024695122479118883	0.8334324315128347	1
+P31040	ecoli_3-ecoli_2	-0.896543297039573	2.1515953301765237e-4	0.00808999844146373
+P31040	ecoli_7-ecoli_2	-0.281826722434416	0.046371631335227724	0.4710421487030117
+P31040	ecoli_7-ecoli_3	0.614716574605157	0.001599563517135337	0.06238772174233911
+P31323	ecoli_2-ecoli_1	0	1	1
+P31323	ecoli_3-ecoli_1	0	1	1
+P31323	ecoli_7-ecoli_1	0	1	1
+P31323	ecoli_3-ecoli_2	0	1	1
+P31323	ecoli_7-ecoli_2	0	1	1
+P31323	ecoli_7-ecoli_3	0	1	1
+P31350	ecoli_2-ecoli_1	0.006997813659817692	0.9571315278885192	1
+P31350	ecoli_3-ecoli_1	-0.07527068595727882	0.5674391434484088	1
+P31350	ecoli_7-ecoli_1	-0.14907644322385022	0.27195179537571224	1
+P31350	ecoli_3-ecoli_2	-0.08226849961709651	0.5328492108125976	1
+P31350	ecoli_7-ecoli_2	-0.15607425688366788	0.2518418189147864	0.9662502439995886
+P31350	ecoli_7-ecoli_3	-0.07380575726657138	0.5748417625536993	1
+P31483	ecoli_2-ecoli_1	-0.006035003268598502	0.9656613538940931	1
+P31483	ecoli_3-ecoli_1	-0.2916175635892251	0.06884181534178724	0.30814907819657145
+P31483	ecoli_7-ecoli_1	-0.12415018789418719	0.38961550604564904	1
+P31483	ecoli_3-ecoli_2	-0.28558256032062657	0.07348231253354942	0.26964859225496696
+P31483	ecoli_7-ecoli_2	-0.11811518462558868	0.41184149396929715	1
+P31483	ecoli_7-ecoli_3	0.1674673756950379	0.2562244024041614	0.827472304138815
+P31948	ecoli_2-ecoli_1	0.16701596506971808	0.30461891471646624	1
+P31948	ecoli_3-ecoli_1	-0.14746886033121517	0.3606263350464176	0.9125977748289751
+P31948	ecoli_7-ecoli_1	0.13570300363942578	0.3979950629027627	1
+P31948	ecoli_3-ecoli_2	-0.31448482540093325	0.07558873593511939	0.26964859225496696
+P31948	ecoli_7-ecoli_2	-0.0313129614302923	0.8413609149536049	1
+P31948	ecoli_7-ecoli_3	0.283171863970641	0.102594068757977	0.4729336340306744
+P34897	ecoli_2-ecoli_1	-0.04035346887726391	0.8231708226600056	1
+P34897	ecoli_3-ecoli_1	-0.24064218166173612	0.20661586959499137	0.7329015751671392
+P34897	ecoli_7-ecoli_1	-0.07188301248915703	0.6916537732347244	1
+P34897	ecoli_3-ecoli_2	-0.20028871278447222	0.2854881458938326	0.6970359925719549
+P34897	ecoli_7-ecoli_2	-0.03152954361189312	0.8612999983358035	1
+P34897	ecoli_7-ecoli_3	0.1687591691725791	0.36291907834879844	1
+P35221	ecoli_2-ecoli_1	3.749052402035959e-18	0.9999999968933682	1
+P35221	ecoli_3-ecoli_1	9.378744493126319e-20	0.9999999999222835	1
+P35221	ecoli_7-ecoli_1	4.1149971569883414e-18	0.99999999659013	1
+P35221	ecoli_3-ecoli_2	-3.6552649571046955e-18	0.9999999969710845	1
+P35221	ecoli_7-ecoli_2	3.659447549523827e-19	0.9999999996967619	1
+P35221	ecoli_7-ecoli_3	4.0212097120570786e-18	0.9999999966678464	1
+P35232	ecoli_2-ecoli_1	-9.35174991389635e-17	0.9999999975112249	1
+P35232	ecoli_3-ecoli_1	-4.256797976875846e-15	0.9999998867141138	1
+P35232	ecoli_7-ecoli_1	-5.478574751823724e-15	0.9999998541990485	1
+P35232	ecoli_3-ecoli_2	-4.163280477736883e-15	0.999999889202889	1
+P35232	ecoli_7-ecoli_2	-5.385057252684761e-15	0.9999998566878234	1
+P35232	ecoli_7-ecoli_3	-1.221776774947878e-15	0.9999999674849346	1
+P35251	ecoli_2-ecoli_1	0.2910600277389265	0.18409674878359403	1
+P35251	ecoli_3-ecoli_1	-0.22632609314316182	0.28911798973956265	0.8112564488214594
+P35251	ecoli_7-ecoli_1	-0.14707478503536597	0.4800001734433751	1
+P35251	ecoli_3-ecoli_2	-0.5173861208820882	0.03499106299174633	0.1731136800644292
+P35251	ecoli_7-ecoli_2	-0.43813481277429245	0.06257682895843478	0.5652269535933546
+P35251	ecoli_7-ecoli_3	0.07925130810779585	0.6995755301924689	1
+P35606	ecoli_2-ecoli_1	0.01472604400022089	0.8596674396867304	1
+P35606	ecoli_3-ecoli_1	-0.05166440017519662	0.5396220379286534	1
+P35606	ecoli_7-ecoli_1	-0.03942033072719498	0.638087082108397	1
+P35606	ecoli_3-ecoli_2	-0.0663904441754175	0.43409865433662387	0.9413246740343568
+P35606	ecoli_7-ecoli_2	-0.054146374727415875	0.5208086692896048	1
+P35606	ecoli_7-ecoli_3	0.012244069448001636	0.8830963642048718	1
+P35637	ecoli_2-ecoli_1	0	1	1
+P35637	ecoli_3-ecoli_1	0	1	1
+P35637	ecoli_7-ecoli_1	0	1	1
+P35637	ecoli_3-ecoli_2	0	1	1
+P35637	ecoli_7-ecoli_2	0	1	1
+P35637	ecoli_7-ecoli_3	0	1	1
+P36578	ecoli_2-ecoli_1	-0.09077461839667414	0.4767538947723877	1
+P36578	ecoli_3-ecoli_1	-0.1631164155750385	0.21709672423562876	0.7388437650084974
+P36578	ecoli_7-ecoli_1	-0.07092681823964987	0.5757231910385889	1
+P36578	ecoli_3-ecoli_2	-0.07234179717836436	0.5682933313236462	1
+P36578	ecoli_7-ecoli_2	0.019847800157024274	0.8743372743211806	1
+P36578	ecoli_7-ecoli_3	0.09218959733538863	0.4701445210054903	1
+P41227	ecoli_2-ecoli_1	0	1	1
+P41227	ecoli_3-ecoli_1	0	1	1
+P41227	ecoli_7-ecoli_1	0	1	1
+P41227	ecoli_3-ecoli_2	0	1	1
+P41227	ecoli_7-ecoli_2	0	1	1
+P41227	ecoli_7-ecoli_3	0	1	1
+P46821	ecoli_2-ecoli_1	3.0556154346516407e-18	0.9999999988008597	1
+P46821	ecoli_3-ecoli_1	8.703459609208835e-18	0.9999999965844297	1
+P46821	ecoli_7-ecoli_1	1.0143300275579541e-17	0.9999999960193813	1
+P46821	ecoli_3-ecoli_2	5.647844174557194e-18	0.9999999977835701	1
+P46821	ecoli_7-ecoli_2	7.0876848409279e-18	0.9999999972185216	1
+P46821	ecoli_7-ecoli_3	1.4398406663707072e-18	0.9999999994349515	1
+P46926	ecoli_2-ecoli_1	0	1	1
+P46926	ecoli_3-ecoli_1	0	1	1
+P46926	ecoli_7-ecoli_1	0	1	1
+P46926	ecoli_3-ecoli_2	0	1	1
+P46926	ecoli_7-ecoli_2	0	1	1
+P46926	ecoli_7-ecoli_3	0	1	1
+P49006	ecoli_2-ecoli_1	-3.687524038971791e-17	0.9999999906329878	1
+P49006	ecoli_3-ecoli_1	-1.2323938771352439e-17	0.9999999968694853	1
+P49006	ecoli_7-ecoli_1	-6.8557369663220705e-18	0.9999999982585124	1
+P49006	ecoli_3-ecoli_2	2.4551301618365468e-17	0.9999999937635026	1
+P49006	ecoli_7-ecoli_2	3.0019503423395835e-17	0.9999999923744753	1
+P49006	ecoli_7-ecoli_3	5.468201805030369e-18	0.9999999986109728	1
+P49327	ecoli_2-ecoli_1	-0.014398550551420511	0.8267441743604874	1
+P49327	ecoli_3-ecoli_1	-0.04196567627482231	0.5280032786342832	1
+P49327	ecoli_7-ecoli_1	-0.02165289739889706	0.7424986310663149	1
+P49327	ecoli_3-ecoli_2	-0.0275671257234018	0.6763652037966709	1
+P49327	ecoli_7-ecoli_2	-0.007254346847476547	0.9120934717626965	1
+P49327	ecoli_7-ecoli_3	0.020312778875925253	0.7578275455770984	1
+P49753, Q86TX2	ecoli_2-ecoli_1	0.0427885695868406	0.6330223765543774	1
+P49753, Q86TX2	ecoli_3-ecoli_1	-0.01258992201393702	0.8875571728728282	1
+P49753, Q86TX2	ecoli_7-ecoli_1	0.013432015508694257	0.8801014988690407	1
+P49753, Q86TX2	ecoli_3-ecoli_2	-0.055378491600777624	0.5384915397622221	1
+P49753, Q86TX2	ecoli_7-ecoli_2	-0.029356554078146344	0.7423029209489327	1
+P49753, Q86TX2	ecoli_7-ecoli_3	0.026021937522631277	0.7705439079706088	1
+P51608	ecoli_2-ecoli_1	-4.2913625582656663e-4	0.9950359256339368	1
+P51608	ecoli_3-ecoli_1	0.01129368462986329	0.8700432034917664	1
+P51608	ecoli_7-ecoli_1	0.0038695445155937044	0.955266026191522	1
+P51608	ecoli_3-ecoli_2	0.011722820885689857	0.8651598401453061	1
+P51608	ecoli_7-ecoli_2	0.0042986807714202714	0.9503121802081855	1
+P51608	ecoli_7-ecoli_3	-0.007424140114269585	0.9143151131043261	1
+P52701	ecoli_2-ecoli_1	-0.12446952652427262	0.35020772156357943	1
+P52701	ecoli_3-ecoli_1	-0.2933974741263691	0.05096510333525755	0.2521431428165374
+P52701	ecoli_7-ecoli_1	-0.11824739391947423	0.37329974035066665	1
+P52701	ecoli_3-ecoli_2	-0.16892794760209645	0.21676724140744885	0.5582498819808271
+P52701	ecoli_7-ecoli_2	0.006222132604798399	0.9614583571498048	1
+P52701	ecoli_7-ecoli_3	0.17515008020689485	0.20215067430909486	0.707527360081832
+P55060	ecoli_2-ecoli_1	1.512516680200544e-19	0.9999999995410115	1
+P55060	ecoli_3-ecoli_1	3.0920357569401238e-21	0.9999999999906168	1
+P55060	ecoli_7-ecoli_1	2.6473797407304766e-19	0.9999999991966257	1
+P55060	ecoli_3-ecoli_2	-1.481596322631143e-19	0.9999999995503945	1
+P55060	ecoli_7-ecoli_2	1.1348630605299326e-19	0.9999999996556144	1
+P55060	ecoli_7-ecoli_3	2.6164593831610755e-19	0.9999999992060089	1
+P55084	ecoli_2-ecoli_1	-0.020985354197746733	0.9083145035324178	1
+P55084	ecoli_3-ecoli_1	-0.36587850015795176	0.07587790499714307	0.3317452590572767
+P55084	ecoli_7-ecoli_1	-0.026413185118933327	0.8847822841459074	1
+P55084	ecoli_3-ecoli_2	-0.344893145960205	0.09049549633425168	0.30380630912213064
+P55084	ecoli_7-ecoli_2	-0.005427830921186594	0.976225634489364	1
+P55084	ecoli_7-ecoli_3	0.3394653150390184	0.09470744770391253	0.44749269040098666
+P62258	ecoli_2-ecoli_1	-1.6365900961718313e-17	0.999999995585274	1
+P62258	ecoli_3-ecoli_1	-2.0529806879056454e-17	0.9999999944620541	1
+P62258	ecoli_7-ecoli_1	-2.341593016684689e-17	0.9999999936835181	1
+P62258	ecoli_3-ecoli_2	-4.163905917338142e-18	0.9999999988767803	1
+P62258	ecoli_7-ecoli_2	-7.05002920512858e-18	0.9999999980982441	1
+P62258	ecoli_7-ecoli_3	-2.8861232877904373e-18	0.999999999221464	1
+P62851	ecoli_2-ecoli_1	0	1	1
+P62851	ecoli_3-ecoli_1	0	1	1
+P62851	ecoli_7-ecoli_1	0	1	1
+P62851	ecoli_3-ecoli_2	0	1	1
+P62851	ecoli_7-ecoli_2	0	1	1
+P62851	ecoli_7-ecoli_3	0	1	1
+P62910	ecoli_2-ecoli_1	-0.32638921108910657	0.07861623447039474	1
+P62910	ecoli_3-ecoli_1	0.4992296707502156	0.017387178417865128	0.13901624882226976
+P62910	ecoli_7-ecoli_1	0.1799351621258511	0.288942595922993	1
+P62910	ecoli_3-ecoli_2	0.8256188818393222	0.001617941997466919	0.027371442899113155
+P62910	ecoli_7-ecoli_2	0.5063243732149577	0.016396966912835098	0.3431241521774416
+P62910	ecoli_7-ecoli_3	-0.3192945086243646	0.08382596512244189	0.43897455293348076
+P62995	ecoli_2-ecoli_1	0	1	1
+P62995	ecoli_3-ecoli_1	0	1	1
+P62995	ecoli_7-ecoli_1	0	1	1
+P62995	ecoli_3-ecoli_2	0	1	1
+P62995	ecoli_7-ecoli_2	0	1	1
+P62995	ecoli_7-ecoli_3	0	1	1
+P67809	ecoli_2-ecoli_1	0.11162058472393903	0.44123896597830237	1
+P67809	ecoli_3-ecoli_1	-0.17473353206867628	0.24190138148853318	0.757957661997404
+P67809	ecoli_7-ecoli_1	-0.06101471008539844	0.6689954100723253	1
+P67809	ecoli_3-ecoli_2	-0.2863541167926153	0.07421964427265682	0.26964859225496696
+P67809	ecoli_7-ecoli_2	-0.17263529480933745	0.24706082528234066	0.9662502439995886
+P67809	ecoli_7-ecoli_3	0.11371882198327783	0.43307568030557997	1
+P68066	ecoli_2-ecoli_1	0.015501866027911499	0.9535892188616891	1
+P68066	ecoli_3-ecoli_1	0.01614008238092068	0.9516811862229217	1
+P68066	ecoli_7-ecoli_1	0.12238909567653394	0.6479526692671542	1
+P68066	ecoli_3-ecoli_2	6.382163530091814e-4	0.9980879792638377	1
+P68066	ecoli_7-ecoli_2	0.10688722964862245	0.6896161281566102	1
+P68066	ecoli_7-ecoli_3	0.10624901329561327	0.691356841755611	1
+P68919	ecoli_2-ecoli_1	-0.18070306430647548	0.5498653830802418	1
+P68919	ecoli_3-ecoli_1	1.3872571664132127	0.002564358299636018	0.0564017163422299
+P68919	ecoli_7-ecoli_1	0.4317988975824582	0.17993668013721403	1
+P68919	ecoli_3-ecoli_2	1.5679602307196883	0.0013590005070912748	0.027371442899113155
+P68919	ecoli_7-ecoli_2	0.6125019618889337	0.07423082194146557	0.6067562836954578
+P68919	ecoli_7-ecoli_3	-0.9554582688307546	0.014724693500875035	0.2529970065150347
+P69797	ecoli_2-ecoli_1	-0.6912228250747892	0.15171453873553425	1
+P69797	ecoli_3-ecoli_1	1.8080750766328495	0.005044011436849354	0.06773386786626275
+P69797	ecoli_7-ecoli_1	0.7360124736141069	0.13096046483287052	1
+P69797	ecoli_3-ecoli_2	2.4992979017076387	9.924710669857034e-4	0.02332307007416403
+P69797	ecoli_7-ecoli_2	1.427235298688896	0.0145427295776082	0.3431241521774416
+P69797	ecoli_7-ecoli_3	-1.0720626030187426	0.04353619964183219	0.35775398836114275
+P76177	ecoli_2-ecoli_1	-0.20190865619375953	0.5204452847470222	1
+P76177	ecoli_3-ecoli_1	2.274678495929805	2.5451201172613534e-4	0.015949419401504482
+P76177	ecoli_7-ecoli_1	1.2230008790566853	0.006132734159795274	0.3383231185087619
+P76177	ecoli_3-ecoli_2	2.4765871521235647	1.587994387975473e-4	0.007463573623484723
+P76177	ecoli_7-ecoli_2	1.4249095352504448	0.0029584092057748346	0.17252957790922283
+P76177	ecoli_7-ecoli_3	-1.0516776168731197	0.012021703045107211	0.22721018755252628
+P78371	ecoli_2-ecoli_1	-0.0677599211194803	0.5932791721964055	1
+P78371	ecoli_3-ecoli_1	-0.04713222596767819	0.7089680640101175	1
+P78371	ecoli_7-ecoli_1	0.03969343076576584	0.7529597095017062	1
+P78371	ecoli_3-ecoli_2	0.020627695151802114	0.8697785015747068	1
+P78371	ecoli_7-ecoli_2	0.10745335188524614	0.4032944051057167	1
+P78371	ecoli_7-ecoli_3	0.08682565673344403	0.49620875586420343	1
+P80723	ecoli_2-ecoli_1	4.242284898585835e-19	0.9999999994421869	1
+P80723	ecoli_3-ecoli_1	-5.022198086628369e-19	0.9999999993396369	1
+P80723	ecoli_7-ecoli_1	1.0603894457316567e-18	0.999999998605706	1
+P80723	ecoli_3-ecoli_2	-9.264482985214203e-19	0.9999999987818238	1
+P80723	ecoli_7-ecoli_2	6.361609558730732e-19	0.9999999991635192	1
+P80723	ecoli_7-ecoli_3	1.5626092543944935e-18	0.9999999979453429	1
+Q01844	ecoli_2-ecoli_1	0.1472277962746012	0.287677669182952	1
+Q01844	ecoli_3-ecoli_1	-0.3913459576346946	0.020517185896244242	0.14396823865960495
+Q01844	ecoli_7-ecoli_1	-0.13302630802719442	0.33260466970257985	1
+Q01844	ecoli_3-ecoli_2	-0.5385737539092958	0.004994778826467312	0.05680098562596089
+Q01844	ecoli_7-ecoli_2	-0.28025410430179565	0.06742247776741404	0.5761557191033564
+Q01844	ecoli_7-ecoli_3	0.2583196496075002	0.08593681724094597	0.43897455293348076
+Q04637	ecoli_2-ecoli_1	1.0633028226236153e-15	0.9999999696250227	1
+Q04637	ecoli_3-ecoli_1	-4.330286036902505e-15	0.9999998762983251	1
+Q04637	ecoli_7-ecoli_1	-3.9484415270793794e-15	0.9999998872063356	1
+Q04637	ecoli_3-ecoli_2	-5.3935888595261206e-15	0.9999998459233479	1
+Q04637	ecoli_7-ecoli_2	-5.011744349702994e-15	0.9999998568313584	1
+Q04637	ecoli_7-ecoli_3	3.8184450982312544e-16	0.9999999890919895	1
+Q08211	ecoli_2-ecoli_1	0	1	1
+Q08211	ecoli_3-ecoli_1	0	1	1
+Q08211	ecoli_7-ecoli_1	0	1	1
+Q08211	ecoli_3-ecoli_2	0	1	1
+Q08211	ecoli_7-ecoli_2	0	1	1
+Q08211	ecoli_7-ecoli_3	0	1	1
+Q12788	ecoli_2-ecoli_1	0.021523852468640966	0.8380992852416475	1
+Q12788	ecoli_3-ecoli_1	-0.08347075382437336	0.43672551453403974	1
+Q12788	ecoli_7-ecoli_1	-0.04960902837798663	0.6396510658409729	1
+Q12788	ecoli_3-ecoli_2	-0.10499460629301433	0.33329214400401946	0.7832365384094457
+Q12788	ecoli_7-ecoli_2	-0.0711328808466276	0.5051970510221664	1
+Q12788	ecoli_7-ecoli_3	0.03386172544638673	0.7483613103793575	1
+Q13423	ecoli_2-ecoli_1	-0.009293665034315068	0.8091022857841039	1
+Q13423	ecoli_3-ecoli_1	-0.012671612972870193	0.7422396207447655	1
+Q13423	ecoli_7-ecoli_1	-0.0059809234803922876	0.8763213913670214	1
+Q13423	ecoli_3-ecoli_2	-0.003377947938555125	0.9299206920719505	1
+Q13423	ecoli_7-ecoli_2	0.003312741553922781	0.9312694660848045	1
+Q13423	ecoli_7-ecoli_3	0.006690689492477906	0.8618096129943021	1
+Q13813	ecoli_2-ecoli_1	0.056437694196225796	0.669430264680854	1
+Q13813	ecoli_3-ecoli_1	-0.08004683639051711	0.5478127007320519	1
+Q13813	ecoli_7-ecoli_1	-0.31070158174990337	0.046211525981118086	1
+Q13813	ecoli_3-ecoli_2	-0.1364845305867429	0.31833453061094324	0.7575555918336371
+Q13813	ecoli_7-ecoli_2	-0.36713927594612916	0.024859293669378453	0.3541980827733886
+Q13813	ecoli_7-ecoli_3	-0.23065474535938624	0.11395676855219242	0.4810629649021967
+Q14498	ecoli_2-ecoli_1	0.4735857611037756	0.2756371328898704	1
+Q14498	ecoli_3-ecoli_1	1.171068310415349	0.02319165864439281	0.15034592500502925
+Q14498	ecoli_7-ecoli_1	0.8643848746130394	0.06895042732929872	1
+Q14498	ecoli_3-ecoli_2	0.6974825493115734	0.12604874552255316	0.3822123251329031
+Q14498	ecoli_7-ecoli_2	0.3907991135092638	0.3613208561003868	1
+Q14498	ecoli_7-ecoli_3	-0.3066834358023096	0.46820223995086263	1
+Q14554	ecoli_2-ecoli_1	-0.33191409809396827	0.0969750466296197	1
+Q14554	ecoli_3-ecoli_1	0.1540032576775984	0.4020523760463079	0.9942703361266808
+Q14554	ecoli_7-ecoli_1	0.17784251153444	0.3374475705133541	1
+Q14554	ecoli_3-ecoli_2	0.48591735577156664	0.026798847702499747	0.13766030061862333
+Q14554	ecoli_7-ecoli_2	0.5097566096284083	0.022089827884421397	0.3541980827733886
+Q14554	ecoli_7-ecoli_3	0.023839253856841602	0.893957550060682	1
+Q14676	ecoli_2-ecoli_1	1.0786499693906202e-15	0.999999960569669	1
+Q14676	ecoli_3-ecoli_1	-3.1683433847600785e-15	0.9999998841803812	1
+Q14676	ecoli_7-ecoli_1	-8.432043490624875e-16	0.9999999691764451	1
+Q14676	ecoli_3-ecoli_2	-4.246993354150698e-15	0.9999998447500502	1
+Q14676	ecoli_7-ecoli_2	-1.921854318453108e-15	0.9999999297461142	1
+Q14676	ecoli_7-ecoli_3	2.325139035697591e-15	0.999999915003936	1
+Q14974	ecoli_2-ecoli_1	0.13132829843155394	0.3184441894804006	1
+Q14974	ecoli_3-ecoli_1	-0.06428728240742473	0.6148384561371222	1
+Q14974	ecoli_7-ecoli_1	0.2143454939548933	0.12389494305020687	1
+Q14974	ecoli_3-ecoli_2	-0.19561558083897868	0.15438348380695663	0.45216079987951757
+Q14974	ecoli_7-ecoli_2	0.08301719552333936	0.5185736085706267	1
+Q14974	ecoli_7-ecoli_3	0.27863277636231804	0.05772814367697735	0.38966496981959714
+Q14978	ecoli_2-ecoli_1	0.2133015824760371	0.10570506922586277	1
+Q14978	ecoli_3-ecoli_1	-0.14648774196610614	0.24025013179064786	0.757957661997404
+Q14978	ecoli_7-ecoli_1	0.018911579853216964	0.8722823123121851	1
+Q14978	ecoli_3-ecoli_2	-0.35978932444214323	0.017807030699448844	0.09941469785383684
+Q14978	ecoli_7-ecoli_2	-0.19439000262282013	0.133814154258856	0.7380551296658859
+Q14978	ecoli_7-ecoli_3	0.1653993218193231	0.1912717150302932	0.6951991180908733
+Q14980	ecoli_2-ecoli_1	0.16229009224115606	0.1876132175110573	1
+Q14980	ecoli_3-ecoli_1	-0.1512822900588161	0.21534333738626213	0.7388437650084974
+Q14980	ecoli_7-ecoli_1	-0.01176481356517526	0.9181518259539676	1
+Q14980	ecoli_3-ecoli_2	-0.3135723822999722	0.027092718738771615	0.13766030061862333
+Q14980	ecoli_7-ecoli_2	-0.17405490580633132	0.16163022467626148	0.8212562767334366
+Q14980	ecoli_7-ecoli_3	0.13951747649364085	0.24898759523967362	0.8255904473736546
+Q15084	ecoli_2-ecoli_1	0.024387217433196183	0.8547469833132166	1
+Q15084	ecoli_3-ecoli_1	-0.16476305887429635	0.23858935764354405	0.757957661997404
+Q15084	ecoli_7-ecoli_1	0.007286043744137778	0.9563360597046059	1
+Q15084	ecoli_3-ecoli_2	-0.18915027630749254	0.18223027871379202	0.4894184628313271
+Q15084	ecoli_7-ecoli_2	-0.017101173689058405	0.8977942205435446	1
+Q15084	ecoli_7-ecoli_3	0.17204910261843412	0.22034744915295118	0.7436726408912102
+Q15120	ecoli_2-ecoli_1	0.20449047795300865	0.19869462630983062	1
+Q15120	ecoli_3-ecoli_1	0.9476924984202942	5.281232447973197e-4	0.02016545530288657
+Q15120	ecoli_7-ecoli_1	0.03925830721847262	0.7909222453570472	1
+Q15120	ecoli_3-ecoli_2	0.7432020204672856	0.001892706157917399	0.027371442899113155
+Q15120	ecoli_7-ecoli_2	-0.16523217073453603	0.28745868009804365	1
+Q15120	ecoli_7-ecoli_3	-0.9084341912018217	6.631282764408766e-4	0.04420017360902241
+Q15181	ecoli_2-ecoli_1	0.08232489810629717	0.4575361567140638	1
+Q15181	ecoli_3-ecoli_1	-0.11156345466488857	0.3222784834451747	0.8797126758352412
+Q15181	ecoli_7-ecoli_1	-0.06418846939768084	0.5591659723003437	1
+Q15181	ecoli_3-ecoli_2	-0.19388835277118574	0.10724816636676099	0.33813039561956004
+Q15181	ecoli_7-ecoli_2	-0.14651336750397803	0.20498743053879417	0.8905353073693035
+Q15181	ecoli_7-ecoli_3	0.04737498526720772	0.6645162460710475	1
+Q15233	ecoli_2-ecoli_1	-1.9343373243961214e-19	0.9999999997058784	1
+Q15233	ecoli_3-ecoli_1	-2.7870969255168805e-19	0.9999999995762138	1
+Q15233	ecoli_7-ecoli_1	-9.294651428479756e-20	0.9999999998586722	1
+Q15233	ecoli_3-ecoli_2	-8.527596011207594e-20	0.9999999998703355	1
+Q15233	ecoli_7-ecoli_2	1.0048721815481455e-19	0.9999999998472062	1
+Q15233	ecoli_7-ecoli_3	1.857631782668905e-19	0.9999999997175417	1
+Q16891	ecoli_2-ecoli_1	0	1	1
+Q16891	ecoli_3-ecoli_1	0	1	1
+Q16891	ecoli_7-ecoli_1	0	1	1
+Q16891	ecoli_3-ecoli_2	0	1	1
+Q16891	ecoli_7-ecoli_2	0	1	1
+Q16891	ecoli_7-ecoli_3	0	1	1
+Q3ZAQ7	ecoli_2-ecoli_1	1.3685994348410747e-21	0.9999999999953806	1
+Q3ZAQ7	ecoli_3-ecoli_1	-1.0181032694406608e-21	0.9999999999965636	1
+Q3ZAQ7	ecoli_7-ecoli_1	6.055199382090307e-22	0.9999999999979562	1
+Q3ZAQ7	ecoli_3-ecoli_2	-2.3867027042817355e-21	0.9999999999919442	1
+Q3ZAQ7	ecoli_7-ecoli_2	-7.6307949663204405e-22	0.9999999999974244	1
+Q3ZAQ7	ecoli_7-ecoli_3	1.6236232076496913e-21	0.9999999999945198	1
+Q5JTZ9	ecoli_2-ecoli_1	5.9904686183013606e-18	0.9999999989600005	1
+Q5JTZ9	ecoli_3-ecoli_1	-6.486772661405592e-17	0.9999999887383763	1
+Q5JTZ9	ecoli_7-ecoli_1	6.384256759841226e-18	0.9999999988916353	1
+Q5JTZ9	ecoli_3-ecoli_2	-7.085819523235728e-17	0.9999999876983767	1
+Q5JTZ9	ecoli_7-ecoli_2	3.9378814153986556e-19	0.9999999999316348	1
+Q5JTZ9	ecoli_7-ecoli_3	7.125198337389714e-17	0.9999999876300115	1
+Q5T1J5, Q9Y6H1	ecoli_2-ecoli_1	0.07669443544313348	0.5641706771130001	1
+Q5T1J5, Q9Y6H1	ecoli_3-ecoli_1	-0.028125483450498312	0.8306554530142143	1
+Q5T1J5, Q9Y6H1	ecoli_7-ecoli_1	0.25254759170648966	0.08733407465960519	1
+Q5T1J5, Q9Y6H1	ecoli_3-ecoli_2	-0.10481991889363179	0.43561301404781405	0.9413246740343568
+Q5T1J5, Q9Y6H1	ecoli_7-ecoli_2	0.17585315626335618	0.20842315704387956	0.8905353073693035
+Q5T1J5, Q9Y6H1	ecoli_7-ecoli_3	0.28067307515698797	0.06314151869256265	0.3977915677631447
+Q5T653	ecoli_2-ecoli_1	0.3718207912028474	0.1793950114788033	1
+Q5T653	ecoli_3-ecoli_1	-0.42564346112307816	0.13193316862976073	0.4960687140479003
+Q5T653	ecoli_7-ecoli_1	-0.3357355696064147	0.219587101107439	1
+Q5T653	ecoli_3-ecoli_2	-0.7974642523259254	0.016006081658335534	0.09706914037958324
+Q5T653	ecoli_7-ecoli_2	-0.7075563608092621	0.026174530943808998	0.3541980827733886
+Q5T653	ecoli_7-ecoli_3	0.08990789151666345	0.7276517713955419	1
+Q6PD74	ecoli_2-ecoli_1	0	1	1
+Q6PD74	ecoli_3-ecoli_1	0	1	1
+Q6PD74	ecoli_7-ecoli_1	0	1	1
+Q6PD74	ecoli_3-ecoli_2	0	1	1
+Q6PD74	ecoli_7-ecoli_2	0	1	1
+Q6PD74	ecoli_7-ecoli_3	0	1	1
+Q6PK04	ecoli_2-ecoli_1	-0.03238231890975527	0.8576445049580141	1
+Q6PK04	ecoli_3-ecoli_1	-0.17588716464086154	0.3436569479317015	0.8973264751549983
+Q6PK04	ecoli_7-ecoli_1	-0.06975759276494618	0.7002791575386312	1
+Q6PK04	ecoli_3-ecoli_2	-0.14350484573110628	0.43537573581372324	0.9413246740343568
+Q6PK04	ecoli_7-ecoli_2	-0.03737527385519092	0.8360421416302029	1
+Q6PK04	ecoli_7-ecoli_3	0.10612957187591536	0.5605582822688204	1
+Q6SZW1	ecoli_2-ecoli_1	0.14470360302319318	0.5450386653707164	1
+Q6SZW1	ecoli_3-ecoli_1	-1.5096626457362943	5.363153006086853e-4	0.02016545530288657
+Q6SZW1	ecoli_7-ecoli_1	-1.0073764235363194	0.004243428956855771	0.3383231185087619
+Q6SZW1	ecoli_3-ecoli_2	-1.6543662487594872	3.2609235726867525e-4	0.010217560527751824
+Q6SZW1	ecoli_7-ecoli_2	-1.1520800265595126	0.0021965702723490597	0.17252957790922283
+Q6SZW1	ecoli_7-ecoli_3	0.5022862221999749	0.0675697420221545	0.40210624801165656
+Q6UXF7, Q8NCF0	ecoli_2-ecoli_1	-0.5322348962386825	0.2649449274574432	1
+Q6UXF7, Q8NCF0	ecoli_3-ecoli_1	1.260816750248338	0.02572000339741912	0.1611786879571598
+Q6UXF7, Q8NCF0	ecoli_7-ecoli_1	0.32390361000065493	0.4835357271135141	1
+Q6UXF7, Q8NCF0	ecoli_3-ecoli_2	1.7930516464870205	0.005489404174745028	0.05680098562596089
+Q6UXF7, Q8NCF0	ecoli_7-ecoli_2	0.8561385062393374	0.09412458872262361	0.63197938142333
+Q6UXF7, Q8NCF0	ecoli_7-ecoli_3	-0.9369131402476831	0.07233657371638266	0.40210624801165656
+Q7Z6I8	ecoli_2-ecoli_1	-0.14746333311104282	0.24092000300819788	1
+Q7Z6I8	ecoli_3-ecoli_1	-0.13539359882738633	0.27823526190855563	0.8112564488214594
+Q7Z6I8	ecoli_7-ecoli_1	-0.08863607211239362	0.4677940056249612	1
+Q7Z6I8	ecoli_3-ecoli_2	0.012069734283656479	0.9198306943541812	1
+Q7Z6I8	ecoli_7-ecoli_2	0.058827260998649177	0.6264399311192593	1
+Q7Z6I8	ecoli_7-ecoli_3	0.0467575267149927	0.6979955208485962	1
+Q86U86	ecoli_2-ecoli_1	-2.3214573172901237e-15	0.999999938074702	1
+Q86U86	ecoli_3-ecoli_1	-5.0775870621797184e-15	0.9999998645544375	1
+Q86U86	ecoli_7-ecoli_1	-1.9864235530109142e-15	0.9999999470117888	1
+Q86U86	ecoli_3-ecoli_2	-2.7561297448895943e-15	0.9999999264797356	1
+Q86U86	ecoli_7-ecoli_2	3.3503376427920966e-16	0.9999999910629132	1
+Q86U86	ecoli_7-ecoli_3	3.0911635091688038e-15	0.9999999175426486	1
+Q8IXK2	ecoli_2-ecoli_1	0.04310786918685115	0.6622039890539471	1
+Q8IXK2	ecoli_3-ecoli_1	-0.09822150471347692	0.3340225468789516	0.8844540677921535
+Q8IXK2	ecoli_7-ecoli_1	-0.02755355115494281	0.7791001268882691	1
+Q8IXK2	ecoli_3-ecoli_2	-0.14132937390032807	0.1798015651985339	0.4894184628313271
+Q8IXK2	ecoli_7-ecoli_2	-0.07066142034179397	0.4793955484292157	1
+Q8IXK2	ecoli_7-ecoli_3	0.0706679535585341	0.47935649349747933	1
+Q8N163	ecoli_2-ecoli_1	0	1	1
+Q8N163	ecoli_3-ecoli_1	0	1	1
+Q8N163	ecoli_7-ecoli_1	0	1	1
+Q8N163	ecoli_3-ecoli_2	0	1	1
+Q8N163	ecoli_7-ecoli_2	0	1	1
+Q8N163	ecoli_7-ecoli_3	0	1	1
+Q8N5M9	ecoli_2-ecoli_1	0.32094647326296943	0.24347795515999016	1
+Q8N5M9	ecoli_3-ecoli_1	0.5171523625104631	0.08084628441993025	0.33775781046548636
+Q8N5M9	ecoli_7-ecoli_1	1.0107446003305482	0.005843579044401133	0.3383231185087619
+Q8N5M9	ecoli_3-ecoli_2	0.1962058892474937	0.4604627263218879	0.9837158244149422
+Q8N5M9	ecoli_7-ecoli_2	0.6897981270675788	0.03057553520215804	0.3832133745337141
+Q8N5M9	ecoli_7-ecoli_3	0.4935922378200851	0.09248474609921227	0.44749269040098666
+Q8NB49	ecoli_2-ecoli_1	0.014303447247493717	0.9570640651710736	1
+Q8NB49	ecoli_3-ecoli_1	0.021884477966020652	0.9263887138385551	1
+Q8NB49	ecoli_7-ecoli_1	0.4777721908693271	0.07942263458342554	1
+Q8NB49	ecoli_3-ecoli_2	0.007581030718526935	0.9772333657807589	1
+Q8NB49	ecoli_7-ecoli_2	0.4634687436218334	0.1181462936467644	0.6730758547149003
+Q8NB49	ecoli_7-ecoli_3	0.45588771290330643	0.09084426459416452	0.44749269040098666
+Q8WVV9	ecoli_2-ecoli_1	0	1	1
+Q8WVV9	ecoli_3-ecoli_1	0	1	1
+Q8WVV9	ecoli_7-ecoli_1	0	1	1
+Q8WVV9	ecoli_3-ecoli_2	0	1	1
+Q8WVV9	ecoli_7-ecoli_2	0	1	1
+Q8WVV9	ecoli_7-ecoli_3	0	1	1
+Q92614	ecoli_2-ecoli_1	-4.766712880949208e-18	0.9999999983271044	1
+Q92614	ecoli_3-ecoli_1	-2.5292317747859303e-17	0.9999999911235671	1
+Q92614	ecoli_7-ecoli_1	-1.925791304007478e-17	0.9999999932413639	1
+Q92614	ecoli_3-ecoli_2	-2.0525604866910094e-17	0.9999999927964627	1
+Q92614	ecoli_7-ecoli_2	-1.449120015912557e-17	0.9999999949142595	1
+Q92614	ecoli_7-ecoli_3	6.034404707784525e-18	0.9999999978822032	1
+Q92804	ecoli_2-ecoli_1	-0.01526906600720486	0.9149761987978576	1
+Q92804	ecoli_3-ecoli_1	-0.30309803381081823	0.06463876699439873	0.29639239499870634
+Q92804	ecoli_7-ecoli_1	-0.08041312717687135	0.578345567444148	1
+Q92804	ecoli_3-ecoli_2	-0.28782896780361333	0.07601795419953855	0.26964859225496696
+Q92804	ecoli_7-ecoli_2	-0.06514406116966648	0.651195878114172	1
+Q92804	ecoli_7-ecoli_3	0.22268490663394688	0.15114605988822408	0.58299194528315
+Q96B54	ecoli_2-ecoli_1	0.036267496559309775	0.7505417888448755	1
+Q96B54	ecoli_3-ecoli_1	-0.12726710127420035	0.2826618191800578	0.8112564488214594
+Q96B54	ecoli_7-ecoli_1	-0.030329266970251643	0.7901203327455304	1
+Q96B54	ecoli_3-ecoli_2	-0.16353459783351013	0.17778809523185052	0.4894184628313271
+Q96B54	ecoli_7-ecoli_2	-0.06659676352956141	0.5626119835301209	1
+Q96B54	ecoli_7-ecoli_3	0.09693783430394871	0.40537464358149444	1
+Q96CT7	ecoli_2-ecoli_1	0	1	1
+Q96CT7	ecoli_3-ecoli_1	0	1	1
+Q96CT7	ecoli_7-ecoli_1	0	1	1
+Q96CT7	ecoli_3-ecoli_2	0	1	1
+Q96CT7	ecoli_7-ecoli_2	0	1	1
+Q96CT7	ecoli_7-ecoli_3	0	1	1
+Q96GQ7	ecoli_2-ecoli_1	0.04657318769054635	0.6217660325428782	1
+Q96GQ7	ecoli_3-ecoli_1	-0.06017836867565262	0.5260585861802811	1
+Q96GQ7	ecoli_7-ecoli_1	0.01766746887464316	0.8505037743061767	1
+Q96GQ7	ecoli_3-ecoli_2	-0.10675155636619897	0.2737995824550741	0.6863242866873858
+Q96GQ7	ecoli_7-ecoli_2	-0.028905718815903193	0.7582746886754799	1
+Q96GQ7	ecoli_7-ecoli_3	0.07784583755029578	0.4162495693926358	1
+Q96HY6	ecoli_2-ecoli_1	0.07578678885530973	0.5957599295443268	1
+Q96HY6	ecoli_3-ecoli_1	-0.2803497871241131	0.08061066125717388	0.33775781046548636
+Q96HY6	ecoli_7-ecoli_1	-0.17688658725905881	0.23695216453157233	1
+Q96HY6	ecoli_3-ecoli_2	-0.35613657597942283	0.03631528972949722	0.1750583197216789
+Q96HY6	ecoli_7-ecoli_2	-0.2526733761143686	0.10807275160664583	0.6426500652299513
+Q96HY6	ecoli_7-ecoli_3	0.10346319986505431	0.4731219104137059	1
+Q96JM3	ecoli_2-ecoli_1	0.013839312371340909	0.9043642067070025	1
+Q96JM3	ecoli_3-ecoli_1	-0.11780820022055583	0.32669598086650625	0.8797126758352412
+Q96JM3	ecoli_7-ecoli_1	-0.3783408228481236	0.013658862308271347	0.5135732227910027
+Q96JM3	ecoli_3-ecoli_2	-0.13164751259189675	0.2777397813356862	0.6870405117251186
+Q96JM3	ecoli_7-ecoli_2	-0.3921801352194645	0.011702353405716	0.3431241521774416
+Q96JM3	ecoli_7-ecoli_3	-0.26053262262756777	0.055672052941647024	0.38966496981959714
+Q96JP5	ecoli_2-ecoli_1	-0.037951836240909184	0.7892633724694473	1
+Q96JP5	ecoli_3-ecoli_1	-0.1585139887195795	0.2817007393442287	0.8112564488214594
+Q96JP5	ecoli_7-ecoli_1	-0.05450056764126529	0.7018261228243217	1
+Q96JP5	ecoli_3-ecoli_2	-0.12056215247867032	0.4055692589222988	0.9298417155779533
+Q96JP5	ecoli_7-ecoli_2	-0.016548731400356113	0.9070477798200682	1
+Q96JP5	ecoli_7-ecoli_3	0.10401342107831421	0.47050486707414163	1
+Q96S52	ecoli_2-ecoli_1	0.10656756870040335	0.3739294680618427	1
+Q96S52	ecoli_3-ecoli_1	0.08870581652012047	0.4551272074178879	1
+Q96S52	ecoli_7-ecoli_1	-0.10702961883576737	0.3719830190329845	1
+Q96S52	ecoli_3-ecoli_2	-0.01786175218028288	0.8779652389740011	1
+Q96S52	ecoli_7-ecoli_2	-0.2135971875361707	0.09913204572054622	0.6389061215473393
+Q96S52	ecoli_7-ecoli_3	-0.19573543535588783	0.12502669843312172	0.5136966522578262
+Q96T58	ecoli_2-ecoli_1	0	1	1
+Q96T58	ecoli_3-ecoli_1	0	1	1
+Q96T58	ecoli_7-ecoli_1	0	1	1
+Q96T58	ecoli_3-ecoli_2	0	1	1
+Q96T58	ecoli_7-ecoli_2	0	1	1
+Q96T58	ecoli_7-ecoli_3	0	1	1
+Q99459	ecoli_2-ecoli_1	0.04718969167866106	0.6013072208263484	1
+Q99459	ecoli_3-ecoli_1	-0.013467415044696188	0.880473029079966	1
+Q99459	ecoli_7-ecoli_1	-0.0475752048330083	0.5983929024100254	1
+Q99459	ecoli_3-ecoli_2	-0.060657106723357244	0.5042781218636153	1
+Q99459	ecoli_7-ecoli_2	-0.09476489651166936	0.3065876324705529	1
+Q99459	ecoli_7-ecoli_3	-0.03410778978831211	0.7044672451480738	1
+Q99460	ecoli_2-ecoli_1	0.2809479191352017	0.046898470370267856	1
+Q99460	ecoli_3-ecoli_1	-0.397261184341352	0.012453381536566308	0.12243983955428418
+Q99460	ecoli_7-ecoli_1	-0.09087276418237754	0.45021985211326854	1
+Q99460	ecoli_3-ecoli_2	-0.6782091034765536	9.583364292467345e-4	0.02332307007416403
+Q99460	ecoli_7-ecoli_2	-0.3718206833175792	0.0164261562212605	0.3431241521774416
+Q99460	ecoli_7-ecoli_3	0.30638842015897444	0.03466163000784896	0.3346874803222741
+Q99733	ecoli_2-ecoli_1	-2.3961539609348188e-20	0.9999999999856952	1
+Q99733	ecoli_3-ecoli_1	-3.9532175854660226e-20	0.9999999999763997	1
+Q99733	ecoli_7-ecoli_1	6.170881674363096e-21	0.9999999999963161	1
+Q99733	ecoli_3-ecoli_2	-1.5570636245312038e-20	0.9999999999907045	1
+Q99733	ecoli_7-ecoli_2	3.013242128371128e-20	0.9999999999820113	1
+Q99733	ecoli_7-ecoli_3	4.5703057529023325e-20	0.9999999999727157	1
+Q99856	ecoli_2-ecoli_1	-1.0786651660314103e-17	0.9999999989304491	1
+Q99856	ecoli_3-ecoli_1	5.888598285797183e-17	0.9999999941611577	1
+Q99856	ecoli_7-ecoli_1	7.968072046729572e-17	0.9999999920992546	1
+Q99856	ecoli_3-ecoli_2	6.967263451828593e-17	0.9999999930916068	1
+Q99856	ecoli_7-ecoli_2	9.046737212760983e-17	0.9999999910297037	1
+Q99856	ecoli_7-ecoli_3	2.07947376093239e-17	0.9999999979380969	1
+Q9BQ69	ecoli_2-ecoli_1	0.011576254428301874	0.9202804682908505	1
+Q9BQ69	ecoli_3-ecoli_1	-0.4476998826308458	0.006830002542778897	0.08025252987765204
+Q9BQ69	ecoli_7-ecoli_1	-0.09093236635065632	0.4436674271857003	1
+Q9BQ69	ecoli_3-ecoli_2	-0.4592761370591477	0.006072863743445153	0.05708491918838444
+Q9BQ69	ecoli_7-ecoli_2	-0.1025086207789582	0.3910504365065559	1
+Q9BQ69	ecoli_7-ecoli_3	0.3567675162801895	0.018215632268894905	0.2648272691400875
+Q9BRP8	ecoli_2-ecoli_1	7.361111938507455e-20	0.9999999998707391	1
+Q9BRP8	ecoli_3-ecoli_1	3.796347616021037e-20	0.9999999999333362	1
+Q9BRP8	ecoli_7-ecoli_1	-3.614187359809819e-20	0.999999999936535	1
+Q9BRP8	ecoli_3-ecoli_2	-3.564764322486419e-20	0.9999999999374029	1
+Q9BRP8	ecoli_7-ecoli_2	-1.0975299298317273e-19	0.999999999807274	1
+Q9BRP8	ecoli_7-ecoli_3	-7.410534975830855e-20	0.9999999998698712	1
+Q9BUL5	ecoli_2-ecoli_1	0	1	1
+Q9BUL5	ecoli_3-ecoli_1	0	1	1
+Q9BUL5	ecoli_7-ecoli_1	0	1	1
+Q9BUL5	ecoli_3-ecoli_2	0	1	1
+Q9BUL5	ecoli_7-ecoli_2	0	1	1
+Q9BUL5	ecoli_7-ecoli_3	0	1	1
+Q9BW92	ecoli_2-ecoli_1	0.20954310359944583	0.09112954528858998	1
+Q9BW92	ecoli_3-ecoli_1	-0.03380596646903464	0.7571671051365705	1
+Q9BW92	ecoli_7-ecoli_1	0.05945079402573421	0.5898202668483452	1
+Q9BW92	ecoli_3-ecoli_2	-0.24334907006848047	0.05817566938135035	0.23776143138464928
+Q9BW92	ecoli_7-ecoli_2	-0.15009230957371164	0.2003158378195754	0.8905353073693035
+Q9BW92	ecoli_7-ecoli_3	0.093256760494768845	0.40612359012693444	1
+Q9BXK5	ecoli_2-ecoli_1	0	1	1
+Q9BXK5	ecoli_3-ecoli_1	0	1	1
+Q9BXK5	ecoli_7-ecoli_1	0	1	1
+Q9BXK5	ecoli_3-ecoli_2	0	1	1
+Q9BXK5	ecoli_7-ecoli_2	0	1	1
+Q9BXK5	ecoli_7-ecoli_3	0	1	1
+Q9BZE9	ecoli_2-ecoli_1	0	1	1
+Q9BZE9	ecoli_3-ecoli_1	0	1	1
+Q9BZE9	ecoli_7-ecoli_1	0	1	1
+Q9BZE9	ecoli_3-ecoli_2	0	1	1
+Q9BZE9	ecoli_7-ecoli_2	0	1	1
+Q9BZE9	ecoli_7-ecoli_3	0	1	1
+Q9GZT9	ecoli_2-ecoli_1	0.044494796306091905	0.7663080819839475	1
+Q9GZT9	ecoli_3-ecoli_1	-0.4556170380241716	0.017746755168800397	0.13901624882226976
+Q9GZT9	ecoli_7-ecoli_1	-0.06741959568284087	0.6540064321376597	1
+Q9GZT9	ecoli_3-ecoli_2	-0.5001118343302635	0.011900763992865188	0.07990512966638055
+Q9GZT9	ecoli_7-ecoli_2	-0.11191439198893277	0.463289888501626	1
+Q9GZT9	ecoli_7-ecoli_3	0.3881974423413307	0.0333568769684855	0.3346874803222741
+Q9H0D6	ecoli_2-ecoli_1	0.009900462784225343	0.9285665345978457	1
+Q9H0D6	ecoli_3-ecoli_1	-0.13586254875506865	0.24180996334632068	0.757957661997404
+Q9H0D6	ecoli_7-ecoli_1	0.007930131149996862	0.9427494245820525	1
+Q9H0D6	ecoli_3-ecoli_2	-0.145763011539294	0.21234568120421343	0.5544581675887795
+Q9H0D6	ecoli_7-ecoli_2	-0.001970331634228481	0.9857614887502557	1
+Q9H0D6	ecoli_7-ecoli_3	0.1437926799050655	0.21794743303820216	0.7436726408912102
+Q9H7E9	ecoli_2-ecoli_1	1.6475586018183628e-23	0.9999999999999544	1
+Q9H7E9	ecoli_3-ecoli_1	-2.5112835266640802e-23	0.9999999999999304	1
+Q9H7E9	ecoli_7-ecoli_1	-2.3138943292019925e-23	0.9999999999999358	1
+Q9H7E9	ecoli_3-ecoli_2	-4.158842128482443e-23	0.9999999999998848	1
+Q9H7E9	ecoli_7-ecoli_2	-3.961452931020355e-23	0.9999999999998902	1
+Q9H7E9	ecoli_7-ecoli_3	1.973891974620877e-24	0.9999999999999944	1
+Q9HCC0	ecoli_2-ecoli_1	0	1	1
+Q9HCC0	ecoli_3-ecoli_1	0	1	1
+Q9HCC0	ecoli_7-ecoli_1	0	1	1
+Q9HCC0	ecoli_3-ecoli_2	0	1	1
+Q9HCC0	ecoli_7-ecoli_2	0	1	1
+Q9HCC0	ecoli_7-ecoli_3	0	1	1
+Q9HD67	ecoli_2-ecoli_1	0	1	1
+Q9HD67	ecoli_3-ecoli_1	0	1	1
+Q9HD67	ecoli_7-ecoli_1	0	1	1
+Q9HD67	ecoli_3-ecoli_2	0	1	1
+Q9HD67	ecoli_7-ecoli_2	0	1	1
+Q9HD67	ecoli_7-ecoli_3	0	1	1
+Q9NQP4	ecoli_2-ecoli_1	1.4268949940329925e-14	0.999999823092748	1
+Q9NQP4	ecoli_3-ecoli_1	-1.4765341427576412e-14	0.9999998169384583	1
+Q9NQP4	ecoli_7-ecoli_1	6.940679654714957e-15	0.9999999139490594	1
+Q9NQP4	ecoli_3-ecoli_2	-2.903429136790634e-14	0.9999996400312063	1
+Q9NQP4	ecoli_7-ecoli_2	-7.32827028561497e-15	0.9999999091436886	1
+Q9NQP4	ecoli_7-ecoli_3	2.170602108229137e-14	0.9999997308875176	1
+Q9NR56	ecoli_2-ecoli_1	0.08314282834204861	0.7583027720061695	1
+Q9NR56	ecoli_3-ecoli_1	-0.301507575947418	0.28605503723407877	0.8112564488214594
+Q9NR56	ecoli_7-ecoli_1	1.0110219387117363	0.007198364223590679	0.3383231185087619
+Q9NR56	ecoli_3-ecoli_2	-0.3846504042894666	0.18531563185072433	0.49069491250614333
+Q9NR56	ecoli_7-ecoli_2	0.9278791103696875	0.010647707125995809	0.3431241521774416
+Q9NR56	ecoli_7-ecoli_3	1.3125295146591542	0.0019805625949948923	0.06238772174233911
+Q9NSD9	ecoli_2-ecoli_1	0.090586857262866	0.4325433275045123	1
+Q9NSD9	ecoli_3-ecoli_1	-0.2526096846778653	0.05701800275655787	0.27485601328802256
+Q9NSD9	ecoli_7-ecoli_1	-0.014093533207053158	0.9002073673140102	1
+Q9NSD9	ecoli_3-ecoli_2	-0.34319654194073135	0.018638942852989296	0.10011775018177106
+Q9NSD9	ecoli_7-ecoli_2	-0.10468039046991917	0.36856531573446605	1
+Q9NSD9	ecoli_7-ecoli_3	0.23851615147081215	0.06830420329686401	0.40210624801165656
+Q9NVA2	ecoli_2-ecoli_1	0.0011073920216477379	0.9904644891117107	1
+Q9NVA2	ecoli_3-ecoli_1	-0.07528114554920282	0.42613631085152326	1
+Q9NVA2	ecoli_7-ecoli_1	-0.0498050430493217	0.5943298515771955	1
+Q9NVA2	ecoli_3-ecoli_2	-0.07638853757085055	0.41963805865338843	0.9413246740343568
+Q9NVA2	ecoli_7-ecoli_2	-0.05091243507096944	0.586309911396484	1
+Q9NVA2	ecoli_7-ecoli_3	0.025476102499881116	0.7838730957133901	1
+Q9NVM6	ecoli_2-ecoli_1	0.013137939630128258	0.8744949217483792	1
+Q9NVM6	ecoli_3-ecoli_1	0.008908146835419573	0.914676039775353	1
+Q9NVM6	ecoli_7-ecoli_1	-0.024112210847154845	0.7722946174881385	1
+Q9NVM6	ecoli_3-ecoli_2	-0.004229792794708686	0.959415292234907	1
+Q9NVM6	ecoli_7-ecoli_2	-0.037250150477283105	0.6559640535230882	1
+Q9NVM6	ecoli_7-ecoli_3	-0.033020357682574414	0.6925393431488356	1
+Q9NVZ3	ecoli_2-ecoli_1	-0.115555974170219	0.39012960500907073	1
+Q9NVZ3	ecoli_3-ecoli_1	-0.44476265430685413	0.011172950170951655	0.11669525734105061
+Q9NVZ3	ecoli_7-ecoli_1	-0.22954445971975124	0.11428647586639432	1
+Q9NVZ3	ecoli_3-ecoli_2	-0.3292066801366351	0.03749766954984198	0.17623904688425732
+Q9NVZ3	ecoli_7-ecoli_2	-0.11398848554953224	0.39620751621823186	1
+Q9NVZ3	ecoli_7-ecoli_3	0.21521819458710287	0.13424620718482863	0.5398411310198428
+Q9NX63	ecoli_2-ecoli_1	0	1	1
+Q9NX63	ecoli_3-ecoli_1	0	1	1
+Q9NX63	ecoli_7-ecoli_1	0	1	1
+Q9NX63	ecoli_3-ecoli_2	0	1	1
+Q9NX63	ecoli_7-ecoli_2	0	1	1
+Q9NX63	ecoli_7-ecoli_3	0	1	1
+Q9P258	ecoli_2-ecoli_1	0	1	1
+Q9P258	ecoli_3-ecoli_1	0	1	1
+Q9P258	ecoli_7-ecoli_1	0	1	1
+Q9P258	ecoli_3-ecoli_2	0	1	1
+Q9P258	ecoli_7-ecoli_2	0	1	1
+Q9P258	ecoli_7-ecoli_3	0	1	1
+Q9UBI1	ecoli_2-ecoli_1	-9.167888951733185e-19	0.9999999991735218	1
+Q9UBI1	ecoli_3-ecoli_1	-4.693072895498515e-18	0.9999999957692307	1
+Q9UBI1	ecoli_7-ecoli_1	-2.4636321723053215e-18	0.9999999977790545	1
+Q9UBI1	ecoli_3-ecoli_2	-3.776284000325197e-18	0.9999999965957089	1
+Q9UBI1	ecoli_7-ecoli_2	-1.5468432771320028e-18	0.9999999986055326	1
+Q9UBI1	ecoli_7-ecoli_3	2.2294407231931937e-18	0.9999999979901762	1
+Q9UBQ7	ecoli_2-ecoli_1	0	1	1
+Q9UBQ7	ecoli_3-ecoli_1	0	1	1
+Q9UBQ7	ecoli_7-ecoli_1	0	1	1
+Q9UBQ7	ecoli_3-ecoli_2	0	1	1
+Q9UBQ7	ecoli_7-ecoli_2	0	1	1
+Q9UBQ7	ecoli_7-ecoli_3	0	1	1
+Q9UDW1	ecoli_2-ecoli_1	1.5538094198099911e-18	0.999999998800712	1
+Q9UDW1	ecoli_3-ecoli_1	1.3027577138548095e-18	0.9999999989944831	1
+Q9UDW1	ecoli_7-ecoli_1	2.4317805807991386e-18	0.9999999981230612	1
+Q9UDW1	ecoli_3-ecoli_2	-2.5105170595518166e-19	0.999999999806229	1
+Q9UDW1	ecoli_7-ecoli_2	8.779711609891475e-19	0.9999999993223492	1
+Q9UDW1	ecoli_7-ecoli_3	1.1290228669443292e-18	0.9999999991285782	1
+Q9UKD2	ecoli_2-ecoli_1	0	1	1
+Q9UKD2	ecoli_3-ecoli_1	0	1	1
+Q9UKD2	ecoli_7-ecoli_1	0	1	1
+Q9UKD2	ecoli_3-ecoli_2	0	1	1
+Q9UKD2	ecoli_7-ecoli_2	0	1	1
+Q9UKD2	ecoli_7-ecoli_3	0	1	1
+Q9UKV3	ecoli_2-ecoli_1	3.2473138333975647e-18	0.9999999989449679	1
+Q9UKV3	ecoli_3-ecoli_1	8.606137536109472e-18	0.9999999972039195	1
+Q9UKV3	ecoli_7-ecoli_1	-1.6020066369825004e-17	0.9999999947951801	1
+Q9UKV3	ecoli_3-ecoli_2	5.358823702711908e-18	0.9999999982589516	1
+Q9UKV3	ecoli_7-ecoli_2	-1.926738020322257e-17	0.9999999937401481	1
+Q9UKV3	ecoli_7-ecoli_3	-2.462620390593448e-17	0.9999999919990996	1
+Q9UQ35	ecoli_2-ecoli_1	0.03819431904921688	0.7123672677261248	1
+Q9UQ35	ecoli_3-ecoli_1	-0.12065597948972538	0.2658920142592635	0.8112564488214594
+Q9UQ35	ecoli_7-ecoli_1	0.03281456595612789	0.7510862166038631	1
+Q9UQ35	ecoli_3-ecoli_2	-0.15885029853894225	0.15633219144770555	0.45216079987951757
+Q9UQ35	ecoli_7-ecoli_2	-0.005379753093088989	0.9583592296279654	1
+Q9UQ35	ecoli_7-ecoli_3	0.15347054544585326	0.16873380848021388	0.6378137960552085
+Q9UQ80	ecoli_2-ecoli_1	-3.245058062541264e-22	0.9999999999997151	1
+Q9UQ80	ecoli_3-ecoli_1	-1.622432239348533e-21	0.999999999998576	1
+Q9UQ80	ecoli_7-ecoli_1	-8.406052653030093e-22	0.9999999999992621	1
+Q9UQ80	ecoli_3-ecoli_2	-1.2979264330944066e-21	0.9999999999988609	1
+Q9UQ80	ecoli_7-ecoli_2	-5.160994590488828e-22	0.999999999999547	1
+Q9UQ80	ecoli_7-ecoli_3	7.818269740455238e-22	0.9999999999993139	1
+Q9Y277	ecoli_2-ecoli_1	0.14640703140398026	0.19920733163596366	1
+Q9Y277	ecoli_3-ecoli_1	0.07161681540455944	0.5109170330942586	1
+Q9Y277	ecoli_7-ecoli_1	0.15187186079560547	0.18479820718899417	1
+Q9Y277	ecoli_3-ecoli_2	-0.0747902159994208	0.49297996527288	1
+Q9Y277	ecoli_7-ecoli_2	0.005464829391625216	0.959351638113686	1
+Q9Y277	ecoli_7-ecoli_3	0.08025504539104603	0.463070159649712	1
+Q9Y3F4	ecoli_2-ecoli_1	9.718799360682765e-19	0.9999999990893496	1
+Q9Y3F4	ecoli_3-ecoli_1	-9.470784099794427e-19	0.9999999991125886	1
+Q9Y3F4	ecoli_7-ecoli_1	2.5065978572661926e-18	0.9999999976513207	1
+Q9Y3F4	ecoli_3-ecoli_2	-1.9189583460477194e-18	0.9999999982019383	1
+Q9Y3F4	ecoli_7-ecoli_2	1.5347179211979163e-18	0.9999999985619711	1
+Q9Y3F4	ecoli_7-ecoli_3	3.4536762672456357e-18	0.9999999967639094	1
+Q9Y490	ecoli_2-ecoli_1	0	1	1
+Q9Y490	ecoli_3-ecoli_1	0	1	1
+Q9Y490	ecoli_7-ecoli_1	0	1	1
+Q9Y490	ecoli_3-ecoli_2	0	1	1
+Q9Y490	ecoli_7-ecoli_2	0	1	1
+Q9Y490	ecoli_7-ecoli_3	0	1	1
+Q9Y493	ecoli_2-ecoli_1	-5.621190015446885e-20	0.999999999907367	1
+Q9Y493	ecoli_3-ecoli_1	-1.977877357361006e-21	0.9999999999967406	1
+Q9Y493	ecoli_7-ecoli_1	-1.0440841581793848e-19	0.9999999998279429	1
+Q9Y493	ecoli_3-ecoli_2	5.423402279710784e-20	0.9999999999106264	1
+Q9Y493	ecoli_7-ecoli_2	-4.819651566346965e-20	0.9999999999205758	1
+Q9Y493	ecoli_7-ecoli_3	-1.0243053846057748e-19	0.9999999998312022	1
+Q9Y4L1	ecoli_2-ecoli_1	5.731449628343196e-22	0.999999999999222	1
+Q9Y4L1	ecoli_3-ecoli_1	5.650050391201009e-22	0.9999999999992331	1
+Q9Y4L1	ecoli_7-ecoli_1	5.596504597081475e-22	0.9999999999992403	1
+Q9Y4L1	ecoli_3-ecoli_2	-8.139923714218677e-24	0.9999999999999889	1
+Q9Y4L1	ecoli_7-ecoli_2	-1.349450312617206e-23	0.9999999999999817	1
+Q9Y4L1	ecoli_7-ecoli_3	-5.354579411953383e-24	0.9999999999999927	1
+Q9Y520	ecoli_2-ecoli_1	-7.0287718444195046e-15	0.9999999121040615	1
+Q9Y520	ecoli_3-ecoli_1	-2.290970576610039e-14	0.999999713510392	1
+Q9Y520	ecoli_7-ecoli_1	-2.0051157417078776e-14	0.9999997492570054	1
+Q9Y520	ecoli_3-ecoli_2	-1.5880933921680886e-14	0.9999998014063305	1
+Q9Y520	ecoli_7-ecoli_2	-1.3022385572659273e-14	0.9999998371529439	1
+Q9Y520	ecoli_7-ecoli_3	2.8585483490216146e-15	0.9999999642533866	1
+Q9Y5B9	ecoli_2-ecoli_1	0.005615071799879606	0.8853387834778575	1
+Q9Y5B9	ecoli_3-ecoli_1	-0.0015531492547019557	0.968164582586059	1
+Q9Y5B9	ecoli_7-ecoli_1	-0.004969573956498814	0.8984304177816331	1
+Q9Y5B9	ecoli_3-ecoli_2	-0.007168221054581562	0.8539972324244992	1
+Q9Y5B9	ecoli_7-ecoli_2	-0.01058464575637842	0.7860801787908229	1
+Q9Y5B9	ecoli_7-ecoli_3	-0.0034164247017968584	0.9300563795409404	1
+P55263	ecoli_2-ecoli_1	0	1	1
+P55263	ecoli_3-ecoli_1	0	1	1
+P55263	ecoli_7-ecoli_1	0	1	1
+P55263	ecoli_3-ecoli_2	0	1	1
+P55263	ecoli_7-ecoli_2	0	1	1
+P55263	ecoli_7-ecoli_3	0	1	1
+P0A6Z3	ecoli_7-ecoli_3	-0.40906290318649974	0.062027760478629304	0.3977915677631447
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/summarised_proteins.tsv	Tue Oct 02 16:30:33 2018 -0400
@@ -0,0 +1,190 @@
+protein	sumIntensity_HEK.Ecoli_10.1_replicate1	sumIntensity_HEK.Ecoli_10.1_replicate2	sumIntensity_HEK.Ecoli_20.1_replicate1	sumIntensity_HEK.Ecoli_20.1_replicate2	sumIntensity_HEK.Ecoli_3.1_replicate1	sumIntensity_HEK.Ecoli_3.1_replicate2	sumIntensity_HEK.Ecoli_7.1_replicate1	sumIntensity_HEK.Ecoli_7.1_replicate2
+A1L0T0	17.429399406156225	17.33398240348946	17.410541528940552	17.169264537725507	16.96506289630559	17.102898046807514	16.810637234848606	17.4312146548945
+O00139	20.421077251892928	19.4956589466802	18.682046032353977	20.423674084830257	21.718035972736907	21.77141317029518	20.840274733873557	20.12149078546466
+O00151	17.81884023410664	17.531832922589587	17.62163842515729	18.09366919995733	17.67254437376755	17.427616936505473	17.96961117579886	17.425397847613464
+O00273	19.93242622242833	19.603203040939114	19.886945840734857	19.867923201248434	19.67920363460759	18.960655886217342	19.507297177954843	19.82377306133697
+O14744	18.77855154110734	18.914172184222327	18.870002449107787	19.08828557498425	18.714199271576717	18.716410902401307	18.88067875222483	18.670156314253507
+O15042	18.319942988998132	18.41974317713256	18.632724745212094	18.567487062998904	18.454088773488962	18.46057387031008	18.357032366321995	18.49783796402044
+O60784	17.992423465315497	18.276485111155022	17.87549658995278	18.230718126797623	17.639386766223552	18.40092918614786	18.262567273424093	17.92554141877697
+O75367	19.90080428618561	20.086975161741446	19.92311091280165	20.106770427549396	19.74046206407978	21.042276581142772	19.99708611108673	20.216996219641395
+O75390	17.22571077073124	14.365033325121281	16.355939065329956	14.361154531483919	16.14733168134587	17.262912073475782	16.914471388538047	15.532376815271153
+O75533	17.358807786199613	17.513044498868947	17.770183697285013	17.804804873091328	17.397513206265078	17.16052774872587	17.399796896788956	17.391955819380776
+O75643	18.687147078461912	18.464501804013604	18.9319587430068	18.424539180514156	18.230533239881822	18.412031679936355	18.656158664410608	18.27259240580123
+O94826	20.816648764635488	21.108362470061817	21.22439537837221	21.037439062994718	20.623862901050362	20.637885957511678	20.907828637962673	20.946104482850195
+O94906	19.86658386516669	19.6225520815111	19.71940800574136	19.80282982980582	20.155700892782455	20.23833594168983	19.875015585018765	19.799828402785874
+O95831	19.368393014683498	19.478356880357524	19.435540943580897	19.49200043099873	19.183100831156857	19.321179939342525	19.380400911298256	19.21652294914462
+P00350	17.445982845969972	17.258215460666293	12.824996608706163	16.7727933274694	18.53500506497499	18.678710595548726	18.01999606718685	16.96248073253443
+P00961, P22570	19.88560203941723	20.527059770503584	19.9578581232248	20.73592480250902	19.854560247709266	19.73516719869701	19.8253881444894	19.814364413056104
+P02413	17.02646765548614	15.922816149814825	12.40490769011839	16.84993989951507	17.791252831461684	18.01712029617799	17.615742136509862	16.457930812458546
+P04075	21.42959310601676	21.801471734933052	22.479144044407132	20.76812531247228	22.114764844510486	21.09866219240143	21.285198547812787	22.72315491597091
+P05091	19.195189557247424	19.154463147845252	19.245763410709632	19.132917551110648	18.87825454159627	18.490128679444485	18.884988470666933	19.052719476482864
+P05386	21.997100208746417	22.25079594317805	22.142419398724616	22.247216901747038	21.713353771644787	21.877160945091283	22.061792137230167	21.932828712958653
+P06454	21.4672010494068	23.130489978942894	22.42852037776938	21.035271651440013	22.0798375570313	22.338423546312274	21.49770599429962	22.555068233536815
+P06753	20.579400629669824	20.731682716674335	20.694202047604044	20.730201909002567	20.507247785171845	20.314059076011112	20.52749633539301	20.750120172458146
+P07813	13.64567258657814	12.959723924937771	13.079990828517749	14.008244926074855	17.44647289469832	17.463475815571833	12.538104361898071	12.275398751832446
+P07814	20.9320719770523	21.124715254002215	21.24004871972877	21.108341720637082	20.69326026886387	20.518943509564615	20.712182975011824	20.996341267837337
+P07954	20.704838120143577	20.717655464797573	20.828570615962096	21.02838431322646	20.894473637888417	20.293768648760704	20.789621388704383	20.723379385706135
+P08312	19.241266524638537	18.51024691548065	18.033368562206096	17.97673317259409	19.129659369036588	19.53616367196932	18.253839960793275	19.582585531448043
+P08559	20.854871537204875	20.586219074407115	21.01052743015398	21.291029297013253	20.660002275073232	20.725343708377753	20.642180615740248	20.82093629538854
+P08574	17.99710509545761	18.71230035180527	18.39524388478352	18.896714252726408	17.936980496139274	18.48301660029015	18.542908376992457	18.552193685378857
+P0A6F5	20.685073535062127	20.38458495055097	19.968914045170944	21.21540489460105	21.278127125776468	21.723019535978064	19.832875262473465	19.88622326179894
+P0A6L0	16.394364842504114	16.15874300680371	16.193045092153486	13.198505913430028	16.753664490374064	17.019652012910928	16.481321230192208	16.552047459439613
+P0A6P9	22.452993328793266	22.012088064561866	21.59277708914616	21.737799804206457	23.767734533376583	23.626555727355115	22.679197974537825	22.68539868659942
+P0A6Y8	19.190154396618073	18.96516178155595	19.170578325628334	19.01853373351607	18.77060092252364	18.65842438317569	18.769762308025875	19.090673097327045
+P0A6Z3	NA	NA	NA	NA	17.179685749122267	17.047190911012443	16.758418391803968	16.409281402621563
+P0A705	18.53227086491931	17.74627593169815	17.54388479691192	18.06912000365964	19.680169983135876	19.84353676737952	19.305104139128982	18.281285712135976
+P0A7J3	21.508736203410145	21.3136847411963	19.609961434937887	21.093056900818077	22.263741120834133	22.36790930444772	21.627187501520325	21.114023408023733
+P0A7V8	21.150778785008775	20.2186520750384	19.36579339747476	20.5807891204694	22.515126058144205	22.52821769622513	21.738115858892186	21.117136324039826
+P0A7Z4	16.554092731105072	16.97365388292919	16.83069579007368	18.06663539792935	18.225404641164886	19.12898288566021	18.728611100219723	17.4686867352536
+P0A8T7	15.968274219972045	14.08221055581862	15.528050594508379	15.332233515077242	17.25469652891128	17.03878397998891	16.15099315632072	14.15635635101027
+P0A910	23.571615142224886	23.47415971211679	23.385034166600985	23.54425266635269	23.498152926380747	23.64388896134665	23.567072874831652	23.240920601925698
+P0ABB4	19.303836610943552	19.255547356626117	19.232374020725846	19.17151897046923	19.574868027830806	19.251457471063716	19.4026728353785	19.250319257106504
+P0ABE2	16.09499197315448	NA	NA	15.555694716493285	16.968001281659163	16.733461745947032	16.728509995785714	15.910812519252847
+P0ABS1	19.755397603831412	19.71062301858138	19.632449854233656	19.83430828273979	20.51056452091128	21.00111362192207	19.866907790159384	19.546634766569106
+P0ACF0	23.86631139839325	23.074450652209297	21.533467592049984	23.510768526861618	24.980030454218362	23.214804215914217	24.42610637379569	23.9012269130233
+P0ADE8	16.14761541475553	15.543569780043683	16.10168238979931	16.507668626577626	17.927112456499852	18.156568496049385	17.188882248037864	15.852088826300271
+P0AE08	23.533594548518263	22.67662674853849	21.191148929770616	22.95174328032391	24.576726481733026	25.20295091288843	23.826221038164483	23.513637813660136
+P0AEE5	15.105320571048892	17.809726135573168	17.07403084817374	17.441979105189077	17.797914497534656	17.675846171025253	17.116030928004644	16.708661717614223
+P0AES9	18.247563912992234	16.418860089908048	15.980890975195209	16.746194999365645	19.08802394498787	19.605347303117753	18.42264886551989	17.433250329642032
+P0AFH8	22.788354502678516	21.60685706520547	21.008189069102198	21.924931838062857	23.95845722962044	23.97569626267418	23.000056491719434	22.838037132540254
+P0DMV8, P0DMV9	21.185607010971903	21.009022522367573	21.462861819262173	21.15340041109471	21.1785921447574	21.0994882787414	20.84410292835595	20.828368897544465
+P0DN79, P35520	20.656813336014213	21.22924536394912	21.668992919408375	19.67115989564083	22.022654982792666	21.59185977325765	21.161874489733446	22.187602233526043
+P10809	23.918481725295827	23.728340611028223	24.02045633819527	24.002586396608894	23.592542981165938	23.79357789513555	23.706849616052203	23.594928742427363
+P11172	17.33412497557539	17.983924568469778	17.520271152208633	17.909337362896014	17.21841938365014	16.670033400937346	17.777774794552897	17.671274947323173
+P11586	20.826226707344283	21.02339337536054	21.25722458424309	20.892497290160474	20.788365750672465	20.76306731888615	20.88085874268038	20.78229794290496
+P11766	19.496855506017738	19.49356434868958	19.456898321760235	19.366569116458507	18.992240682522958	19.012418460218324	19.655026479975806	19.55346192510628
+P12081	21.09581321601022	21.252123987562506	21.33307756376225	21.11082817466208	20.783746753873256	20.74686304877554	21.070042833762056	21.107967592018774
+P12270	18.100242162593744	18.087010541210322	17.983947980693507	18.213160272026382	17.464616986144843	17.24697458386249	17.990381232478068	17.37802873666793
+P13667	20.840546377973777	20.79125231219585	20.875287497917025	20.570690645951647	20.828905583833244	20.55493675839115	21.083473410279105	20.891645891063835
+P13804	18.96409026340988	19.080497461423302	19.060993839249488	19.102577236239686	19.109790157195643	19.647451504405865	19.3312306842602	19.147083161567558
+P13861	19.17675062190914	19.01233709868792	19.25730491796606	19.228636796114706	19.12557260599531	18.87742855336962	19.414482591099503	19.05520715328834
+P15639	27.22386781461154	27.11563265699235	27.101435171797743	27.13395938786404	26.857577254444323	26.84118041689666	26.68530880584831	26.96189716235831
+P17858	17.349826884219848	17.289743356655954	17.36665235803583	17.244834570943276	16.87558255808105	17.05316108385032	17.10458336481529	17.262057879660414
+P19404	19.091648229145534	19.335907911040906	19.126122720575825	19.4154326270275	19.373369182063456	19.27984194988117	19.279814892281077	18.757622373940123
+P19623	20.248579554549103	20.41418726193059	20.68333524657205	20.33109249070303	20.40087671834245	19.78886032987731	20.081192916929872	20.25498992463903
+P20810	18.59074869658884	18.626279628442045	18.818314696767803	18.681981145913834	18.672703440185103	19.118439595370692	18.572506463650235	18.60864658626877
+P20962	19.89764738913706	19.391795629667847	19.573395278110794	19.669999413455415	19.07134795179531	18.83158967234426	18.81065786563648	19.810704567661887
+P21513	18.665329125564412	18.969253958069377	18.66515885786529	18.736583062509805	17.785442960508334	17.18893502781344	18.55188171876094	18.095663735285225
+P22314	19.99802869909462	20.23898117962172	20.45093662209151	21.64669539644452	20.36036649998107	21.825804672597222	20.12053062330203	21.527176173014084
+P23588	20.619838721111883	21.19792956458913	20.619061945191635	21.244232210558334	21.389264486626224	21.35255337043574	21.0980540847613	21.116699145750037
+P25437	16.415115604731543	14.843824895013615	15.675891273544227	16.751027703333314	17.68582643215425	18.087633120160643	16.795736080017566	16.099700327375697
+P25738	21.512662625703374	20.72031856779607	19.52374553861298	21.25528713769584	23.123976655444675	22.983143160246097	22.027890369754545	21.627157776277308
+P25787	20.91071430454846	20.735220442332626	21.124648186664565	20.86853819831193	20.560158479783574	20.05427427786227	20.587773878675762	20.712810499309374
+P26641	17.33854513466603	17.239667994660497	17.18718052789289	17.68590870119181	17.131946954562498	16.731530850053094	17.170471824031093	17.516896646945685
+P27694	20.999411395079207	22.150490156719744	21.758933703984518	20.93041211097332	21.987320965759277	21.527778856479088	21.676866969259162	22.32969041903156
+P27708	18.029590825681584	17.490886979520628	17.97472186039772	17.56183731437009	17.588723751928352	17.539150453196868	17.97142358621467	17.71179009481566
+P28838	20.11602435073906	20.167157831266003	19.935741207699934	20.111719457844604	17.803332067018893	19.693624073240937	20.181127777136474	20.206897391109823
+P29966	19.391636854369924	18.41657673617238	18.434067374047398	19.964684036493697	18.4967604973764	18.175076484563895	18.308572338816383	14.535868523689217
+P31040	20.246905783895595	20.224452514446185	20.543416557107506	20.547152158983835	19.665925020935077	19.44535147956696	20.22445561567296	20.37336383969914
+P31323	17.109099007892766	17.516534700673233	17.28216480831214	17.217739687303073	17.721268199915983	17.107694315754337	17.25244293437952	16.637770920102213
+P31350	19.64329840503016	18.702074835007995	18.796589442260956	18.821803133792258	18.570790432646792	18.6595001905779	18.47677513777618	18.287221600396308
+P31483	20.162178809915616	20.239733885388713	20.33563804823483	20.04894848750568	19.841518590463274	19.723176258638578	20.16810849419155	19.87737589948683
+P31948	18.417893442596764	18.08478975475376	18.708292434937388	18.315376516961827	18.089058165735644	17.953614065357716	18.42725198948384	18.498740031763234
+P34897	22.68307489610648	22.240499635071313	22.219103085719045	22.493673531440574	21.707225988476438	21.959285114688164	21.950363936702104	22.59770906988199
+P35221	19.21961741103082	19.008514228251368	19.191434850803034	19.554870382833823	19.271035034827673	18.631051317765596	19.49634453419406	19.251978206484495
+P35232	20.91519834531592	20.829288882495153	21.04444336906156	20.715950012772062	20.248109584293854	20.84800793743211	20.572092183090437	20.649824263984524
+P35251	18.017553780625313	18.654240140612092	18.64336444868581	18.860023379658085	17.931788872095158	18.09336386814886	18.038402427037994	18.213180941501623
+P35606	18.358599058265657	18.655727554978554	18.46384150341285	18.667641597812136	18.227487311249238	18.37581108029003	18.446003805062595	18.254705145286568
+P35637	18.97417886762393	18.93447982531782	19.12677529633085	18.704399989343052	18.966795159723226	19.181227587225262	18.987370585754554	18.84143798657685
+P36578	24.183492596991787	24.28559371324522	24.207672911366128	23.767051124940384	23.873987793943677	23.706759864549436	23.879160158746327	24.203655806685862
+P41227	17.944211266764942	18.259176165718465	17.98086822146374	18.2191198128853	17.96912666535406	18.059622944844953	17.869999068216533	18.235638612882795
+P46821	17.702485251878702	17.94780451917632	18.14908421446911	17.57023371990325	17.913143807627314	17.93376227335901	17.710789398869036	18.16864353596875
+P46926	17.348932104026925	16.616971265890307	17.366307562082774	17.082086009015075	16.77432391702534	17.944210603375844	17.966420394181885	17.096463393301697
+P49006	22.773279152695903	23.477828589495516	22.75461367579288	22.028681758256	23.273940208102765	22.556213661446634	23.077412744482412	22.909627295827146
+P49327	18.87573581291637	18.879640737774345	18.91485108660645	18.625739723987643	18.543477043925186	18.585890048024986	18.522643655773766	18.909732772338664
+P49753, Q86TX2	19.657973558169683	20.276865280775002	20.22564942584914	20.683827523767192	19.91988164940513	19.898610933685493	20.15620477561999	20.074813509444564
+P51608	18.16208542609288	18.598163598159665	18.796241222683673	17.88251770664299	19.691665100173473	19.21317884015729	17.888319108119454	19.606730450029445
+P52701	18.61304093320748	18.82667284487932	18.448855552012123	18.584397201329395	18.26055461537768	18.297919870642033	18.70886641673636	18.398949598672125
+P55060	19.817542983599438	19.692251006763325	19.966382756204283	19.710894376371016	19.737907693258116	19.774992085119862	19.824885435345426	20.016941046030105
+P55084	19.79301544202344	19.592705910783586	19.994730105163757	19.471658948594566	19.228201689286685	18.74399148242607	19.605560710159974	19.699481656037914
+P55263	NA	16.826690967122488	16.88805927358242	17.243440156644837	17.04983348899187	NA	17.212168654329854	17.02277970209948
+P62258	23.427321765912776	23.371792933283434	23.479517106962007	22.15262828027584	23.207210574740238	23.26744938063684	22.47138839388624	23.368097871016108
+P62851	19.11427313446003	19.173580732846773	19.428889992692017	19.12642124785857	18.995718501178683	19.364061843630264	19.275013662968504	19.141100528528305
+P62910	23.797015976009824	23.295102704614138	23.41398331583223	23.115739878679666	24.273334468054724	24.190495467041025	23.931433149738687	23.838395582671737
+P62995	22.708611730327213	23.39877810459618	23.120107080965944	24.33488752949338	22.813827614175246	22.88769871111117	22.91300697712595	22.845910872806805
+P67809	20.177807873363374	20.47279257704518	20.381931925160693	20.68301261595079	20.11301130800468	19.97026898445637	20.121575438436082	20.330924083358703
+P68066	20.295419012393157	21.737584303099084	19.79733536123554	22.291198297573185	21.53261788707271	20.935111137373635	23.345911102271018	22.357552108756114
+P68919	20.44430388462419	19.695121633058104	18.604036912533036	20.226637959021932	21.852210783502862	21.819457763054377	20.986407859688697	20.605416913278535
+P69797	19.256547429641817	18.52858759389033	17.374501066113453	18.532737015040937	20.642063738043014	21.13338601314679	19.988196703356305	19.421274306639138
+P76177	17.63292113177894	17.422619503525958	17.51092708306688	17.12378803092641	20.03673387606634	19.759776175365776	18.46327086761735	19.435716433278206
+P78371	17.12958573483462	17.75471873927074	17.277624225220944	16.79754671930365	17.262067673609277	17.131451836630667	17.478768028865005	17.69703583413003
+P80723	18.357571991628173	18.367739598856836	18.222033545897233	19.066337961660704	18.358438125823394	18.154698913052027	18.79527233383513	18.49079466550688
+Q01844	20.94221900558612	21.018562754406823	21.367294119502624	21.06976072631083	20.62032615632638	20.472283841368345	20.878204876229475	20.7929288772643
+Q04637	21.780583555405013	21.905116613529472	22.038451852605498	21.822763295398918	21.7770376987464	21.42622188120698	21.762813035792686	21.738399070277435
+Q08211	19.682512380679697	20.045764214592438	19.840418849632556	20.01092399483187	19.85199160310837	19.890116336425653	20.161650787529783	19.884865408701675
+Q12788	19.39511488874021	19.763336770642557	19.65340728145332	19.63122483435345	19.230337560419823	19.360809898797406	19.228252629054218	19.586550005145842
+Q13423	20.356974333274422	20.297816266861993	20.280637121322084	20.115745280892884	20.17261598157001	20.237126161996418	20.291737547911477	20.23989458694693
+Q13813	17.86788280912524	17.68301589647312	17.762807811954833	17.940582866022055	17.569845935903988	17.793838181126922	17.414835050721454	17.369559489180894
+Q14498	19.607858428871833	19.17376116912667	19.646419609537105	20.46610825808022	20.803030909934606	21.269617740516345	20.044845662931905	21.165936870782136
+Q14554	18.09713890076189	19.196413500504537	18.21657787819388	18.348111048159666	18.926257149208123	18.87366994328469	18.886884748381057	18.972603655370747
+Q14676	19.280012333942327	19.21919072891658	19.28032571916831	19.289807999677944	19.15678520460767	18.784873076350788	19.142667353043972	19.30108765965258
+Q14974	20.869580975209093	20.558458385385684	21.047107136567845	20.85879050639627	20.758606590768633	20.626681626235737	21.065008542078434	21.061830266823623
+Q14978	21.438811315362074	21.36320223279786	21.643208632477894	21.634687148708114	21.260915503218754	20.802919436577287	21.392478732526254	21.451727117941665
+Q14980	18.777811495360023	18.511632159605423	18.770628859293875	18.781950200472856	18.162367481220766	18.442241239815104	18.565826544461498	18.59188222130262
+Q15084	20.66195446748928	20.16124712904124	20.576374161925077	20.231008264632703	19.951830935081894	19.95732402476918	20.182089339926197	20.46305945251104
+Q15120	17.18070656530167	17.681681628463785	17.874878814614195	17.764442272482924	18.554473895018056	18.625416304204535	17.71977062784287	17.577043884254607
+Q15181	21.947514937138067	22.13798716285061	22.114120615701673	22.205716683766788	21.882553851021687	21.88538642982214	21.875063146931666	22.027728520045773
+Q15233	23.75329779483852	24.117854970665874	22.468902932813283	23.896483755162343	23.505850938249544	23.399285324729615	23.701681662090206	23.81398647262613
+Q16891	16.87912333722505	16.79728453340341	15.40345150645998	18.665057837965584	16.43352873233142	16.713371950132753	16.772455044415707	16.148860938673323
+Q3ZAQ7	19.583802782752286	19.744624092576718	19.86933743117599	19.70786848211074	19.64040853080259	19.214567436452693	19.58593975244597	19.849917410946322
+Q5JTZ9	17.97531441142971	17.337943267934218	17.892656793854126	17.52895676325362	16.841100265220266	17.257405586006346	18.31467404243229	17.235208918823535
+Q5T1J5, Q9Y6H1	20.425493381079512	20.38662279397354	20.613634997339737	20.412338692352677	20.475955215557565	20.08922704587549	20.796401338275313	20.71992759978258
+Q5T653	19.575859126976365	20.130667763191447	20.12086583342371	20.54197206031	19.574250062835745	19.037535664119904	19.421731568801057	19.421294336216302
+Q6PD74	18.531311694833157	17.8615613500081	19.214543524711154	17.4690669058386	18.664645219856258	18.76102420005303	18.227896493977834	18.857581164342072
+Q6PK04	19.307150030130646	20.071584399532913	19.09342743913647	20.150175300095196	18.79613936019587	18.86467031101727	19.10920660143733	19.358185474788538
+Q6SZW1	16.543712709757553	16.508229211454427	16.81283318847917	16.542000069516536	15.173298237689117	14.53062260782242	15.301522138636393	15.641795082191187
+Q6UXF7, Q8NCF0	20.47926044439826	19.296386749507057	18.410585790209414	19.718065477985782	21.711800595591523	21.495987514197676	20.79545907607471	20.13545588075622
+Q7Z6I8	17.901896299877617	17.926596357063602	17.4480650485878	17.641158231911543	17.691135731681545	17.458596047774474	17.48078774994311	17.903350826709932
+Q86U86	16.09352263447319	16.17090107323122	15.773180439388028	15.981699950849432	15.69610467704312	15.453824899272114	15.472329393748268	16.35608851727099
+Q8IXK2	19.88497631175	20.021195881310742	20.000943476523922	20.002192997605512	19.77858409381743	19.84736270672145	19.874188054495658	19.940362300990365
+Q8N163	18.588750784298558	18.364665978348917	18.647068673719467	18.236014640840086	18.034985413965472	18.348628303094337	18.778515918356565	17.90705789553958
+Q8N5M9	19.425514839262807	19.038318889453212	19.880515619982425	18.805508836580405	19.96577876783866	19.786074045760483	20.393461336624906	20.55174283595144
+Q8NB49	16.624341734734568	17.20868910912399	16.94782063538518	NA	17.253922117451495	16.57030398897301	17.64661661125378	17.792262594515186
+Q8WVV9	18.04134715026137	18.116965121771727	20.592083452764385	17.6888220693879	19.27593703316569	18.110636148633922	17.842350904417565	20.466272623774422
+Q92614	17.144108994945515	16.849997036654138	17.147533193593198	16.722734623923778	16.554903064566787	16.782113786682903	17.049460869898038	16.444328566721914
+Q92804	19.843530391774326	19.67454779602865	19.71795984387364	19.756396028367618	19.40781687731223	19.16793168975971	19.843740546984392	19.48168730032511
+Q96B54	17.98934790896758	18.05185867811008	18.155230489687323	18.036474818688802	17.82648209171516	17.686605991958043	18.152350165799206	17.76238866957935
+Q96CT7	19.807368198354865	20.03196656286514	19.938512789752846	20.082830381761468	20.085933371943316	19.83510268502541	18.37094662317126	20.223809973879458
+Q96GQ7	19.971603406497067	20.16156622347129	20.261238207603363	20.121115780874657	19.978237891859564	19.832954460233015	19.982572523745688	20.24512481876126
+Q96HY6	20.06654696495705	19.802222472698638	20.08492446017291	19.979175687972774	19.68239805512427	19.38456748785797	19.669070246430646	19.743796740582532
+Q96JM3	18.460510018110195	18.92930228919158	18.475648026603835	18.667354695018837	18.340891029364442	18.359751167673778	18.007478434771453	18.084274141491083
+Q96JP5	18.52399086668668	18.23637888097176	18.003592914945518	18.63262743006775	17.974979252113258	17.59300397757935	18.194909743185892	18.217901373765237
+Q96S52	17.95137262453612	18.479482512412684	18.53356284489412	18.561175675787016	18.50390834600535	18.54040362719686	18.24922310994655	18.242496814913533
+Q96T58	17.508524751426492	17.943468103968492	17.637109246554644	18.198675023028084	18.02474967617525	17.43799416525012	18.07708537322329	17.782046333316167
+Q99459	20.647039840903904	20.61310437799519	20.976521075448716	20.7192535368043	20.45251986236501	20.706432949639893	20.366716142227784	20.551415418953507
+Q99460	16.678066230348705	16.713263025721623	16.92353094400643	17.040828079779132	16.28448219551921	16.296581282872037	16.653252567183046	16.552729884713195
+Q99733	20.25521758395315	22.466826461325248	21.903315453507382	19.56024521501972	20.43882550070749	20.206950200758417	21.289758314429182	21.756386441141448
+Q99856	17.606306948376606	18.782855047651122	18.674988341480738	16.82829366672183	19.188809641538988	18.03264285937012	18.62515833565983	18.717736258325544
+Q9BQ69	20.029308951915898	20.059541202685285	20.120799427819577	19.99881369796741	19.55068682748217	19.615777240315005	19.981771965507328	19.919732262020723
+Q9BRP8	18.667324308242755	18.798915044389243	18.81867625796836	19.204537175007218	19.29542602817347	18.50314192109646	18.329281149674127	18.83403654441184
+Q9BUL5	17.22246039723171	17.358222541345693	17.244491747429787	16.954452958630675	17.168482921122266	17.34876641231786	17.057712905947966	17.392088526933982
+Q9BW92	17.578933869173984	17.53218951089423	17.740494807885195	17.815196522578848	17.54912559117438	17.49027484041151	17.60513920535436	17.632115348660516
+Q9BXK5	17.251606058241894	18.08487665625192	17.365666796377784	17.937819717273882	17.35767689521971	17.87500662337109	17.861913256452663	17.61402418680151
+Q9BZE9	17.239653187833376	17.102107066336135	17.480154114774205	17.034983146399156	16.9470939740401	17.07880098071914	16.99876289014337	17.414889602691552
+Q9GZT9	17.850270483131986	17.980298965225508	17.914136619545793	18.01975151391226	17.481030486185848	17.21601992290004	17.97103308927676	17.70298537887075
+Q9H0D6	19.644737988370718	19.852678679684917	19.632877246170615	19.90242255403838	19.428693903446064	19.548858289447775	19.712134225824826	19.815626297149134
+Q9H7E9	17.90918941590644	17.766277280931128	18.36096701228016	17.895743997822297	17.527485832178726	17.769743761360832	17.537971755556658	17.798157884953607
+Q9HCC0	19.563035919477528	19.88221135839258	19.624406971425472	19.706683431387454	19.637669223526814	19.71416259537343	19.350694023769943	19.747854290299138
+Q9HD67	17.311503426624515	18.863251531206338	17.141748428756816	19.395117023421104	18.76711019642094	18.537316009920808	17.27523405286614	18.96616617823518
+Q9NQP4	18.381992780894073	18.917342783690636	18.700815821100313	18.9449180683599	18.440197198267427	18.5006894574546	18.88945630852811	18.578373771486596
+Q9NR56	17.527467338588085	17.406266304205605	17.48732628416503	17.633310690969264	17.209498005764317	16.768806812235862	18.560553843645334	20.779573157350768
+Q9NSD9	20.260112284508004	20.33725220720365	20.374991360751938	20.41333460024103	20.064569059225516	19.914681245402434	20.29802407402645	20.26963056914974
+Q9NVA2	19.227234525084985	19.71949336258945	19.307413066976924	19.408235002054344	19.055120825704527	19.125408379408963	19.2854800824329	19.07351494308126
+Q9NVM6	16.189775588344876	15.42492996262315	15.973049642323907	16.032155129525865	15.657127408253032	16.222355154686813	15.489195659005436	15.408822206173735
+Q9NVZ3	17.282924195015518	17.41743525153856	17.163123243151933	17.27563593366205	16.855788767145903	16.837699064396688	17.198302561764745	16.942827001822593
+Q9NX63	27.61542358963342	27.911810556297343	28.083704552515947	26.340554792065955	27.790015233690823	27.53417616029855	27.311840374025447	28.109264195566265
+Q9P258	18.854104423391533	18.783437657094034	19.063949688427243	18.564336176957124	18.751187054309867	18.30398899082033	18.85791805991519	18.542470478717966
+Q9UBI1	17.17532443562314	17.04021875625573	17.094918834959667	17.000661650271816	16.595893302506965	16.900121883887536	16.605104013053506	17.19184634264942
+Q9UBQ7	18.497796471827527	18.66504444587331	18.54398557657811	18.459303410008992	18.556142482175055	18.488962555856503	18.560641305258766	18.473942500808484
+Q9UDW1	17.72275179207305	17.091312832053486	17.39032748100914	18.715891835385587	17.766957888034064	17.957711114874975	17.973616070475458	18.395663919273247
+Q9UKD2	17.602054127060505	17.955546765962904	17.8901930620816	17.796521255379435	17.702438155687524	19.73275157024674	17.57861298734829	17.66750848772918
+Q9UKV3	18.350798819361223	18.54073759450185	19.38296957984295	18.26193108227035	18.44607676424905	19.19684808765253	18.226488162442728	17.950271001595933
+Q9UQ35	18.992018492308727	19.034042869048083	19.031358461228336	19.144204924503008	18.884010264820045	18.68841686175156	19.062705172656287	19.04220998710539
+Q9UQ80	19.840453766271562	22.5208176873743	19.526427133983372	22.102332734379736	19.25251476631551	19.287204498902398	19.77455114014043	19.521747780454486
+Q9Y277	19.41170362936939	19.264298615973612	19.628662725779577	19.557115106835187	19.290475577244873	19.58643160446498	19.568766989916277	19.63580855221468
+Q9Y3F4	21.54974061472226	21.316870873301298	21.874817977862882	21.259499602890912	21.05003163812364	21.555705382555267	21.80856975466665	21.748488663591274
+Q9Y490	17.439191543962504	17.38623899591387	17.116663080479213	17.208583108608906	17.048216319660234	17.607632907934455	18.111915202152897	17.253459102498674
+Q9Y493	16.567183814603716	16.25139665530373	15.82267523092488	16.5568554992602	16.655146313944623	16.147985709342695	16.259223151054282	15.743862954426387
+Q9Y4L1	17.970727823088914	17.685865020656987	18.484681253289267	18.10409126860764	17.955056523539668	19.269827350823732	17.946850066265174	19.140763609160445
+Q9Y520	18.470945306148195	18.540737325069752	18.964892430347312	18.11246787159243	18.263633784457113	17.9587034962231	18.103363924927663	18.217463570844114
+Q9Y5B9	16.710544893958957	17.020808054506446	16.961379225581133	17.24296573162254	17.085438153147674	16.515083487716716	16.754906083174312	16.557829107222858