Mercurial > repos > galaxyp > metaquantome_db
view test-data/func_full_test_out.tab @ 6:e63db1aa82ee draft default tip
planemo upload for repository https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/metaquantome commit ec66b5b0627e7cf15b6e67e90d82ba8e0743b761
| author | galaxyp |
|---|---|
| date | Mon, 18 Mar 2024 12:34:24 +0000 |
| parents | 7c45aa1c9464 |
| children |
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id name namespace NS_mean WS_mean X730NS X730WS X733NS X733WS X734NS X734WS X737NS X737WS X760NS X760WS X769NS X769WS X781NS X781WS X795NS X795WS X852NS X852WS X861NS X861WS X866NS X866WS X867NS X867WS X730NS_n_peptide X730WS_n_peptide X733NS_n_peptide X733WS_n_peptide X734NS_n_peptide X734WS_n_peptide X737NS_n_peptide X737WS_n_peptide X760NS_n_peptide X760WS_n_peptide X769NS_n_peptide X769WS_n_peptide X781NS_n_peptide X781WS_n_peptide X795NS_n_peptide X795WS_n_peptide X852NS_n_peptide X852WS_n_peptide X861NS_n_peptide X861WS_n_peptide X866NS_n_peptide X866WS_n_peptide X867NS_n_peptide X867WS_n_peptide X730NS_n_samp_children X730WS_n_samp_children X733NS_n_samp_children X733WS_n_samp_children X734NS_n_samp_children X734WS_n_samp_children X737NS_n_samp_children X737WS_n_samp_children X760NS_n_samp_children X760WS_n_samp_children X769NS_n_samp_children X769WS_n_samp_children X781NS_n_samp_children X781WS_n_samp_children X795NS_n_samp_children X795WS_n_samp_children X852NS_n_samp_children X852WS_n_samp_children X861NS_n_samp_children X861WS_n_samp_children X866NS_n_samp_children X866WS_n_samp_children X867NS_n_samp_children X867WS_n_samp_children log2fc_NS_over_WS p_NS_over_WS corrected_p_NS_over_WS GO:0000015 phosphopyruvate hydratase complex cellular_component 25.886058501686048 27.75998767351391 26.063085341729952 26.75868414835451 26.872321573535828 27.714535507520914 25.66138683343686 26.91922948200433 24.56792307320876 27.02361179346473 26.027647781700306 28.016086841596714 26.02628222102915 27.691319718917903 26.16224176931668 28.14922479286621 25.58935659144236 28.605803973702113 24.96556438729523 27.182932679501942 26.61887047167179 28.06289719214795 23.98035185379387 28.471187733625282 25.803186314724893 26.966628159317192 9.0 12.0 9.0 21.0 7.0 12.0 12.0 15.0 9.0 16.0 6.0 10.0 20.0 15.0 12.0 16.0 9.0 13.0 9.0 19.0 13.0 12.0 11.0 16.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.8739291718278608 4.146041132679973e-05 0.0005099643033035255 GO:0000027 ribosomal large subunit assembly biological_process 24.93071577771554 25.59199706393845 24.79502406577661 24.90569362782595 24.98653026336489 25.54103884489353 23.235856648559913 25.931788552669854 25.039623407494012 25.45976392090486 24.544491045410794 25.52182426968223 25.141851834365106 25.289466690231773 25.900937208609022 25.935471942444728 24.03595672520859 26.011397107654144 24.664753825097794 25.84980444944989 24.843398416694487 25.350436246047447 25.80464628461343 25.501822202499124 24.28178647007801 25.41548110918182 14.0 6.0 12.0 32.0 12.0 12.0 20.0 11.0 24.0 15.0 21.0 13.0 25.0 15.0 17.0 16.0 26.0 17.0 19.0 11.0 26.0 12.0 15.0 15.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6612812862229092 0.00268017172806849 0.006910856026093958 GO:0000036 acyl carrier activity molecular_function 25.95712476206603 26.279571177686467 26.5301700656991 25.713248274935196 23.51705029509677 23.162225189828625 25.71677865632887 27.34753252356737 24.76249594346933 27.104656358315633 25.695589715923877 27.215607058954525 25.964407715885855 25.376217309281692 24.710785124891835 24.76949157731373 26.583389308611466 26.855652944530483 27.299615071207107 26.21417524637679 25.987672484095224 25.62275900338784 25.498246974021807 25.479528439599648 25.891370301559785 26.106957744939113 8.0 5.0 4.0 6.0 9.0 8.0 9.0 6.0 7.0 8.0 8.0 5.0 5.0 5.0 11.0 6.0 9.0 8.0 8.0 7.0 9.0 6.0 8.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.32244641562043697 0.6033317722918665 0.6716842567531217 GO:0000049 tRNA binding molecular_function 29.33438467030648 29.866410348871714 29.34869846467857 29.421655277196997 29.2837931122148 29.981729378140212 28.84739681956653 29.861138275832506 29.511822916465768 29.5789021928085 29.26397852161527 29.849840976877704 29.19847063527141 29.680573984412536 29.78160947364881 30.14265486546316 28.83697494656853 29.77400766267598 29.84406783531248 29.98304230286376 29.04660382106465 29.921153355794505 29.468392401488643 30.22790968805213 29.19134574545442 29.780293851199517 249.0 200.0 202.0 317.0 265.0 303.0 358.0 279.0 347.0 312.0 313.0 210.0 384.0 318.0 274.0 292.0 407.0 369.0 265.0 267.0 339.0 295.0 301.0 312.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5320256785652333 0.0005320055051392492 0.0019244720881558927 GO:0000096 sulfur amino acid metabolic process biological_process 25.641959534489395 25.02519905424221 22.959333969267963 23.56617038671472 23.2811176590562 24.9233842298084 26.658059206677017 24.71600470247653 26.719294793011407 24.32032110610373 26.110935955574764 25.50979902501469 25.68957971560552 25.75618941024313 25.57953594946143 25.12564077833513 26.01574198154432 24.60018760892095 24.59250284691585 24.578890808316242 23.604724502619945 24.807705716945176 25.63748385358932 26.17432881676495 25.808312526691452 24.27889106591759 24.0 23.0 37.0 49.0 45.0 67.0 43.0 39.0 51.0 74.0 72.0 69.0 42.0 42.0 33.0 60.0 59.0 44.0 47.0 42.0 70.0 64.0 46.0 62.0 3.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 0.6167604802471836 0.24821307898992373 0.31935043564889154 GO:0000097 sulfur amino acid biosynthetic process biological_process 24.48919762883691 23.855859618980237 21.94449841091107 22.111110105590935 22.185119630614334 23.8716549776372 25.53932931633112 23.62775341263033 25.380265043354694 23.198728272477197 24.88000008620307 24.403050057551308 24.61040906623584 24.435282855898226 24.300300177460045 23.883442861177183 25.013762891394286 23.48275460911573 23.50973838248063 23.47123854707627 22.56413974250645 23.73944221283695 24.482137502279482 24.968620240779714 24.77690153202385 23.130282930302826 11.0 7.0 17.0 21.0 21.0 28.0 20.0 16.0 24.0 30.0 34.0 25.0 20.0 17.0 16.0 25.0 28.0 18.0 22.0 18.0 31.0 24.0 21.0 27.0 2.0 2.0 1.0 2.0 3.0 2.0 2.0 1.0 3.0 2.0 3.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 0.6333380098566721 0.16585666034291002 0.2267131567447445 GO:0000105 histidine biosynthetic process biological_process 20.255069716984945 21.32070278544089 NA 17.522825967863508 20.22054942031172 22.03364873556927 18.58090432156576 21.38780893999375 19.553081126362184 21.416920955914016 18.9103548465036 21.739519693658035 19.440818951600505 20.18967588936324 17.480047411265602 22.618204731739173 18.159611833312656 19.993924848826595 22.721207278556427 20.90766700362468 17.31087076754614 21.51794839167449 18.424948105304484 21.42346941671312 21.11603468305396 20.460524498176614 NA 1.0 6.0 14.0 2.0 7.0 5.0 14.0 4.0 6.0 3.0 3.0 1.0 10.0 2.0 7.0 9.0 8.0 1.0 8.0 4.0 8.0 3.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.065633068455945 0.013823023820376656 0.02725297587334924 GO:0000155 phosphorelay sensor kinase activity molecular_function 19.781085235855574 21.24045677343729 NA 19.32140204426424 19.24819361821376 20.250106571485023 18.45760031912512 21.555908461586746 19.63067972700698 21.83751162227165 19.21477237554313 19.61768545599882 18.521276423702467 22.75145827363407 16.9435189378526 21.969271984873643 19.759345147109293 19.631766440086203 21.57824014064527 20.53065018218418 NA 21.305083131111367 20.04051976825436 21.500796605895943 19.942049871736966 20.120947495869586 NA 4.0 3.0 6.0 2.0 9.0 3.0 9.0 4.0 4.0 2.0 14.0 1.0 10.0 3.0 5.0 11.0 9.0 NA 4.0 2.0 8.0 3.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.459371537581717 0.008351423441556883 0.017785966646865173 GO:0000160 phosphorelay signal transduction system biological_process 23.99825739893877 21.753314196806027 21.31249302217822 20.75052444014234 20.557123709666573 20.422972640522726 24.02477603749795 21.167188818481605 25.150858175130075 21.274387436553376 24.621610903698247 20.27560358020376 24.430865460056964 23.30283890392484 24.771501177406375 21.49356089995331 22.682588202103467 21.142727024155985 23.86256912626821 23.071204155134048 19.915200942392246 18.47494073802112 23.609477278868862 22.46948269874056 24.827565204219948 21.24764744135088 9.0 7.0 5.0 8.0 19.0 11.0 28.0 7.0 27.0 9.0 25.0 14.0 33.0 18.0 14.0 9.0 34.0 20.0 5.0 4.0 25.0 15.0 25.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.244943202132742 0.007911788680711459 0.016907384030013527 GO:0000166 nucleotide binding molecular_function 33.03800820500537 33.094578586630924 32.629780591701525 32.49195850934575 32.65250713672666 33.182475663111056 32.81384183414382 33.259447236699124 33.029944185990104 33.055977639849445 33.24975956388671 33.122295254800036 33.07266353330599 32.74976744600976 33.13217598002622 33.221312521823144 32.653140649011995 33.088237551918084 33.62769911695573 33.32607650623971 33.24793219003643 33.18095804138817 32.98030720946472 33.041168005837704 33.02696291019515 33.219313447563835 2677.0 2747.0 2518.0 3603.0 3874.0 4392.0 4612.0 4133.0 4719.0 4216.0 4598.0 3428.0 4824.0 4200.0 3591.0 4270.0 5953.0 5254.0 3338.0 3407.0 4400.0 4106.0 4404.0 4312.0 6.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 6.0 6.0 6.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 6.0 6.0 -0.056570381625554944 0.27265646879500405 0.34545713000625894 GO:0000270 peptidoglycan metabolic process biological_process 23.01324767927422 24.358561549083465 23.32460388467092 23.912639313898982 23.198211598693987 23.47661030115901 22.08935159549552 25.068044319114872 23.194814012008546 24.166017556336364 22.823993951347042 25.09090393654459 23.370164946227746 25.00864640896668 23.07214575567697 24.109813022773853 23.040171174773842 23.489031378117765 23.33906857006095 24.24681925510624 22.231710454509287 23.74237946272693 22.68080814438131 24.776704604162997 23.168440591659042 23.80080035466043 18.0 24.0 18.0 21.0 16.0 40.0 16.0 34.0 22.0 35.0 27.0 30.0 16.0 32.0 19.0 26.0 32.0 33.0 19.0 26.0 20.0 28.0 27.0 29.0 2.0 3.0 2.0 2.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 1.0 2.0 3.0 -1.345313869809246 3.225641456243767e-05 0.0005099643033035255 GO:0000272 polysaccharide catabolic process biological_process 21.615611609608717 20.906131137910013 22.39240835591338 18.819407963120465 20.953387818454964 NA 18.123208428888493 22.833767984022174 18.722907500820106 18.625790201803127 18.287613179765614 18.530838967640687 19.687166574972178 20.89527132252889 22.242966405629343 21.587564292538566 18.19056277079027 16.938603895306276 21.575454227049807 18.422146138935414 22.834840460642877 21.437451432224226 23.37598626470165 20.24506724851401 21.186097510484807 21.624319429635047 3.0 2.0 2.0 NA 1.0 3.0 2.0 2.0 4.0 3.0 5.0 4.0 4.0 5.0 1.0 2.0 5.0 1.0 6.0 2.0 4.0 4.0 4.0 4.0 2.0 2.0 1.0 NA 1.0 2.0 2.0 2.0 2.0 1.0 3.0 1.0 2.0 2.0 1.0 1.0 3.0 1.0 3.0 2.0 2.0 2.0 3.0 4.0 0.7094804716987042 0.5382526579885007 0.6140213136834085 GO:0000287 magnesium ion binding molecular_function 28.802590795254048 29.08938746033646 28.208658674084724 28.188227098254586 28.157650415632443 28.961868169546186 28.611257201100017 29.225415340003533 28.995333768149944 29.059039766839323 29.29054289236381 29.00011927709475 29.098557232927842 29.083549031871943 28.963635082592894 29.338415730633372 28.246245316349892 29.37742728168916 28.873294056650906 29.08014100838264 28.541004995287004 28.74186667015148 29.051305573061967 29.398042583025852 29.039407753842145 29.23687058045016 316.0 317.0 308.0 418.0 406.0 480.0 446.0 511.0 476.0 545.0 487.0 361.0 475.0 527.0 349.0 562.0 587.0 604.0 410.0 437.0 506.0 499.0 477.0 541.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.28679666508241297 0.03766692222862868 0.06276144050911694 GO:0000453 enzyme-directed rRNA 2'-O-methylation biological_process 19.185076632222163 19.671117989695283 17.907227744393424 16.300106932898014 NA 19.793798663797702 18.83528003668958 19.423618731431308 18.64189406923416 18.693120145849733 20.577099081282828 19.10907184480968 19.472870509626308 19.807233036923357 19.434724918799066 20.692741836823107 19.274606254234964 14.881118420013385 NA NA 18.364813382678822 NA 18.041701063306586 21.391742521383385 19.18424877994717 18.05462550942302 1.0 2.0 NA 4.0 4.0 4.0 2.0 3.0 6.0 4.0 4.0 3.0 4.0 5.0 4.0 1.0 NA NA 2.0 NA 3.0 5.0 4.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4860413574731197 0.6501474440948545 0.7123652416421232 GO:0000721 (R,R)-butanediol dehydrogenase activity molecular_function 20.73686238988459 20.81388879153064 21.079656262117805 21.693561651735678 22.183889495180694 NA 20.533841282471386 21.578268974280572 19.65024599977336 19.81233168987293 18.04215446780693 NA 20.969353118888648 20.98516252964611 20.716594096870857 18.896127700217008 20.16465122709429 17.07227584641224 NA NA 18.296094492037355 NA NA NA 21.315655541943787 21.395447640990554 5.0 4.0 13.0 NA 2.0 9.0 4.0 5.0 1.0 NA 3.0 3.0 5.0 2.0 1.0 1.0 NA NA 3.0 NA NA NA 5.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.07702640164605157 0.6962703401140228 0.7516828585314017 GO:0000902 cell morphogenesis biological_process 21.909652061141614 23.913713601328613 24.120277761482306 23.27006162641892 22.717889293649158 24.280569795290003 20.369533953493388 23.63699700773745 18.48233745582464 23.54219220203269 20.813279348637987 23.89239460384843 21.720535372916626 24.50803310825817 21.433083521900148 24.0910195475024 20.551278986011027 23.279740918015968 21.83712273002397 23.641300198653962 21.72227249378581 24.049599742736397 20.201356016428512 24.73605771316496 21.15970743592041 22.93290583352778 10.0 9.0 7.0 17.0 4.0 15.0 1.0 14.0 6.0 15.0 9.0 13.0 7.0 17.0 5.0 15.0 8.0 11.0 5.0 15.0 5.0 15.0 8.0 19.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.0040615401869992 0.0002755038114342687 0.0011655212090507369 GO:0000967 rRNA 5'-end processing biological_process 19.332111383579672 23.00184309820375 20.71957469872902 21.898220870297546 19.969766520048246 21.276964660641234 16.723456970047888 23.056123805269397 NA 22.73431670028919 18.227775609456067 23.083675505479555 19.855699898422767 24.48194549238309 17.523421069103442 21.822011963183183 NA 23.101591550646273 18.469209636083168 23.037374891987408 NA 22.233762818656025 NA 23.97088338116146 19.22139542182732 21.792074635965506 7.0 7.0 3.0 8.0 1.0 5.0 NA 8.0 3.0 10.0 4.0 9.0 1.0 8.0 NA 11.0 2.0 11.0 NA 5.0 NA 8.0 3.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.6697317146240778 0.00021282941901437674 0.0009941074345388681 GO:0000976 transcription regulatory region sequence-specific DNA binding molecular_function 21.09257803700318 20.990262401985987 20.596012052525577 21.067840585265962 23.040069036615968 NA 18.071702324456734 19.65051868970745 19.217473234379305 22.12969197992931 18.804941792888773 NA 19.65205804861992 15.854362070072984 20.907646547289595 NA NA NA 19.468217270905896 21.416917320251642 22.616364466416954 21.057473019796234 NA NA 19.717859457201268 20.880096910508442 5.0 6.0 7.0 NA 2.0 4.0 4.0 7.0 1.0 NA 3.0 1.0 3.0 NA NA NA 3.0 6.0 7.0 6.0 NA NA 5.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.10231563501719165 0.4349671606144283 0.5194631736333076 GO:0001123 transcription initiation from bacterial-type RNA polymerase promoter biological_process 22.51097752343185 23.26731791815145 22.12822805530665 22.35202834118245 22.773753698938087 23.56504073236461 22.088756008807724 23.10872452726752 22.773285887433254 23.198475380513806 21.684864979759634 23.10197951666181 22.3514236320996 22.71535852018115 22.874787081192807 24.433988766185927 21.805891630845046 23.555787540662852 22.958754982033795 22.93905469741283 22.84611224678575 23.191127631354572 22.798977743185826 23.247910239472972 22.329199526227704 22.576448544543386 6.0 9.0 15.0 14.0 9.0 15.0 12.0 13.0 11.0 19.0 13.0 10.0 12.0 14.0 6.0 15.0 16.0 13.0 16.0 14.0 15.0 14.0 12.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7563403947195972 0.0022136919545913893 0.006045268182341475 GO:0001217 bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding molecular_function 21.09257803700318 20.990262401985987 20.596012052525577 21.067840585265962 23.040069036615968 NA 18.071702324456734 19.65051868970745 19.217473234379305 22.12969197992931 18.804941792888773 NA 19.65205804861992 15.854362070072984 20.907646547289595 NA NA NA 19.468217270905896 21.416917320251642 22.616364466416954 21.057473019796234 NA NA 19.717859457201268 20.880096910508442 5.0 6.0 7.0 NA 2.0 4.0 4.0 7.0 1.0 NA 3.0 1.0 3.0 NA NA NA 3.0 6.0 7.0 6.0 NA NA 5.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.10231563501719165 0.4349671606144283 0.5194631736333076 GO:0001510 RNA methylation biological_process 22.11131863508894 22.99006999626487 23.753812358543282 21.53415720850437 22.643982040848627 23.62178325906221 19.57662061936412 23.053937003909965 19.478375359903268 21.886079741459064 21.86764508639241 23.39943636152789 22.132784379288573 22.254964576545962 23.241707876069192 24.25577818039425 20.77862212323861 22.671960524795505 21.341706816862136 22.59853726121048 22.562655379283857 22.734441635305682 18.51830648488816 23.21672008838359 21.410034974629546 22.412464059853395 10.0 16.0 14.0 34.0 7.0 24.0 3.0 18.0 15.0 27.0 14.0 14.0 13.0 43.0 8.0 27.0 13.0 16.0 13.0 15.0 5.0 33.0 15.0 15.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 -0.878751361175933 0.02092133533779403 0.038284203081476474 GO:0001533 cornified envelope cellular_component 22.388904800996933 22.251394660128547 20.179028747167767 17.545763377115296 20.689852080035696 21.945123801554324 NA 20.97920577412264 21.529605941585626 22.512239852054233 24.08429902864781 23.46478779426319 24.236345445983552 23.55524644239912 21.938548182741226 21.501866145155166 22.824291684778203 22.027920769310807 20.12762330519268 20.332641749963862 21.076586739822105 17.277566491780313 20.83150917443016 23.808739013959322 18.129467111308625 18.247252566958586 5.0 2.0 7.0 8.0 NA 9.0 7.0 4.0 14.0 13.0 15.0 12.0 7.0 11.0 9.0 13.0 5.0 5.0 8.0 2.0 9.0 8.0 2.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.1375101408683861 1.0 1.0 GO:0001882 nucleoside binding molecular_function 31.116884152032718 30.094703243173925 30.180059220896435 28.85069936000325 29.924150573189486 30.34190341605751 30.817118347044172 29.843260421803908 31.279744571675728 30.20377232592904 31.310111530444388 30.40244691788544 31.18769730918569 29.647642149635626 31.14682424675253 29.740609339424573 30.59077702072109 29.780212856021546 31.731191358558426 30.335300599296023 31.65851814797008 30.57651461417325 31.43052032315677 30.09199952427768 31.07287365254164 30.515217014485344 395.0 222.0 239.0 328.0 453.0 412.0 592.0 444.0 540.0 451.0 452.0 273.0 623.0 373.0 455.0 410.0 662.0 582.0 453.0 330.0 558.0 356.0 521.0 441.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0221809088587932 0.0006583371695572323 0.0022696264851033866 GO:0002161 aminoacyl-tRNA editing activity molecular_function 25.879189552827054 26.657648694314442 25.45062253593915 26.15808597854889 25.276688964658014 26.843289528835488 25.722874351512022 26.54358318074268 26.415356985788478 26.186652076581268 26.20185835029179 26.66038115740809 26.198209494818364 26.74972181875981 26.63240427478189 27.46546516813941 24.900409948409656 26.277396277700237 25.803457769758353 26.47896027967261 24.876615815571977 26.290763805544408 25.936007900659696 27.136423837145877 25.979148861830197 26.457945286578212 61.0 73.0 69.0 103.0 101.0 107.0 111.0 101.0 110.0 103.0 123.0 91.0 104.0 115.0 82.0 114.0 132.0 112.0 78.0 96.0 111.0 113.0 119.0 112.0 NA 1.0 1.0 NA 2.0 NA 2.0 NA 2.0 NA NA 1.0 2.0 NA 2.0 NA NA NA NA NA 2.0 2.0 2.0 NA -0.7784591414873887 0.0009986863791802587 0.0031633517797384847 GO:0002949 tRNA threonylcarbamoyladenosine modification biological_process 19.42142077148372 20.48238681991573 18.2139724845997 18.955344846288085 17.18510121272384 20.398821783568234 19.888125920968864 20.62338804601965 19.66711092666897 19.895264402667607 20.31771481653455 20.490300074278288 19.06483976084689 20.64781851946788 18.266177362329408 19.32981329527091 18.85427939387311 19.946936067512073 19.306288503677198 19.994044171541574 NA 19.019563233973397 18.73244512804336 22.329805287079346 20.730190849603726 NA 1.0 2.0 1.0 1.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 5.0 2.0 1.0 2.0 3.0 5.0 2.0 NA 1.0 4.0 4.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.060966048432011 0.023485516000298128 0.04253980256657774 GO:0003674 molecular_function molecular_function 36.294894533838246 36.26814564164379 35.80941330869881 35.568001856399945 35.718623348401884 36.221169612166904 36.035306128584686 36.35718400508416 36.36617333438527 36.29223312938254 36.49180705386549 36.3704616395266 36.3919869038483 35.968288310700935 36.478131810874416 36.40246181355366 35.957571693237774 36.293521330345314 36.81611259964689 36.48939383004162 36.435632788868475 36.25896542972465 36.367996978893366 36.300545539709155 36.29007448991863 36.4732538738152 28032.0 26662.0 24958.0 34813.0 35579.0 42071.0 43013.0 40414.0 43957.0 41758.0 43435.0 33532.0 46363.0 42320.0 33619.0 41821.0 54120.0 49702.0 33929.0 33691.0 41609.0 40253.0 42013.0 42578.0 9.0 9.0 9.0 9.0 9.0 9.0 11.0 9.0 10.0 9.0 9.0 9.0 10.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 10.0 9.0 0.026748892194454754 0.6861059569955559 0.7413508522341591 GO:0003676 nucleic acid binding molecular_function 32.08484593659842 32.309544225610374 31.904889205962835 31.736881855599126 31.761776533519228 32.316054532886824 31.577203986139413 32.28792731735519 32.09172174623473 32.19397198864653 32.04017604620143 32.45230814620207 32.126377608754396 32.150636615924306 32.380930831179015 32.532797946090106 31.66370958534565 32.26031651784528 32.630453125027174 32.46090928746193 32.159752098964766 32.28204109218175 32.396122988160144 32.54996070002552 31.90477639136101 32.32154042634459 1453.0 1173.0 1195.0 1733.0 1475.0 1714.0 1946.0 1593.0 1898.0 1803.0 1762.0 1462.0 2172.0 1833.0 1466.0 1679.0 2318.0 2074.0 1640.0 1441.0 1836.0 1709.0 1747.0 1794.0 4.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 2.0 4.0 4.0 3.0 3.0 3.0 2.0 3.0 4.0 -0.224698289011954 0.03766692222862868 0.06276144050911694 GO:0003677 DNA binding molecular_function 28.58915792941645 28.651603499877762 28.3141027062641 28.653803788416987 28.21235127413404 28.36231488079505 27.986691252611447 28.504540801619267 28.58093439189705 28.62068592100733 28.69686254725995 28.783654465599884 28.89980154178469 28.550841228079303 28.74987505091331 28.89356402985361 28.31040547739803 28.58377507799904 28.77539186600565 29.14102710885622 28.762142898615647 28.312048981338982 28.70519223954863 28.846155202573662 28.78027619402109 28.320055726090107 258.0 273.0 243.0 268.0 268.0 334.0 325.0 302.0 359.0 358.0 371.0 390.0 350.0 356.0 237.0 300.0 464.0 429.0 291.0 244.0 337.0 359.0 397.0 342.0 4.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 4.0 4.0 6.0 5.0 5.0 5.0 4.0 4.0 5.0 5.0 -0.062445570461310496 0.6861059569955559 0.7413508522341591 GO:0003678 DNA helicase activity molecular_function 21.37042323374512 21.15884447924653 20.732561193891197 21.419467000815846 22.604966262901353 21.900359528302463 20.682157523370854 19.016924150166066 19.4188620869316 18.30949710128917 21.840304838834324 21.564269876044808 22.06344237297992 21.731374814558983 21.166543351122197 21.080772005170587 22.6039215243302 18.108770009298247 19.483822079003048 19.364380961865514 20.930453550014683 20.953451571222985 19.168308204204553 22.12244245763239 20.811870786976787 21.99017126169573 5.0 9.0 5.0 5.0 8.0 2.0 5.0 3.0 16.0 10.0 16.0 18.0 5.0 9.0 6.0 3.0 3.0 8.0 5.0 3.0 6.0 10.0 10.0 14.0 1.0 2.0 1.0 2.0 1.0 1.0 2.0 1.0 2.0 3.0 2.0 3.0 1.0 2.0 2.0 1.0 2.0 3.0 1.0 1.0 2.0 3.0 2.0 3.0 0.21157875449859276 0.7728299926844475 0.8146045868836069 GO:0003684 damaged DNA binding molecular_function 19.397655499806632 21.85895399296762 NA 20.297217779851717 20.11863078925049 20.967538850144773 17.434547657967233 20.015572100527763 19.027558617567767 19.035797429587408 19.55274522933994 20.879065334715204 20.29853090316332 22.55932138054907 15.934826795709824 24.53810144210852 17.491607888749662 18.837248606166565 21.269808719320267 19.34952551328244 16.698841904578938 18.425063039256308 16.466220970811644 22.521340214080357 19.450629972198733 19.47439181085655 NA 15.0 7.0 12.0 4.0 12.0 3.0 4.0 7.0 13.0 7.0 31.0 1.0 15.0 4.0 4.0 13.0 9.0 1.0 5.0 2.0 20.0 7.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.4612984931609887 0.042254020654422304 0.06966052546462224 GO:0003690 double-stranded DNA binding molecular_function 21.895802325508946 21.340311067974845 20.596012052525577 21.39212813130395 23.05749333397735 19.58399801254411 21.097352421130648 20.64069313719213 22.54896074093923 22.12969197992931 21.357004624253786 16.19150343483952 21.62191860506433 21.21562274685005 22.311996725926267 21.00945562290422 20.832047320342923 20.654379713923575 19.71612392899535 22.54185043822108 22.64618687578453 21.160125433431546 21.535057566927925 21.77455528088708 22.157747921301237 21.853961840558068 5.0 12.0 9.0 4.0 10.0 9.0 25.0 7.0 12.0 2.0 14.0 12.0 16.0 7.0 8.0 8.0 4.0 12.0 8.0 7.0 15.0 13.0 25.0 7.0 1.0 2.0 1.0 1.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 0.5554912575341007 0.2040238704744366 0.2705863871967023 GO:0003697 single-stranded DNA binding molecular_function 22.87616743980422 22.72893543317178 21.51825885986436 23.23928589436656 21.255885709692713 22.71694392912933 21.85716206865531 22.671237256685377 21.415413894844196 22.096165805859613 22.758358765440434 21.6844357799792 22.53167089437514 21.034400335927472 23.56156804740587 23.202858068436623 21.81898288339911 22.952479323726077 23.24059006060249 22.911378701960825 24.573804462921014 23.044816254312835 23.30279612036561 23.600227478175892 22.470307936261573 21.47404807517341 7.0 6.0 3.0 6.0 3.0 6.0 3.0 5.0 5.0 7.0 3.0 5.0 11.0 6.0 5.0 10.0 7.0 8.0 6.0 6.0 7.0 9.0 5.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.1472320066324393 0.8624902301359216 0.8917877441670506 GO:0003723 RNA binding molecular_function 31.886002319492803 32.08876548655776 31.685887788960123 31.44582529145089 31.528873226816692 32.110355229476205 31.395213594685725 32.083815089821336 31.899143347832307 31.970230123522306 31.814127570016822 32.22497672001275 31.9018286090268 31.93653670173592 32.196717677133 32.2965036177158 31.42433286518117 32.0275108651037 32.480102948482035 32.212508831405394 31.962497526059856 32.098735301899026 32.23861925918207 32.32386613243623 31.665484272361503 32.146953050499434 1073.0 770.0 829.0 1302.0 1072.0 1217.0 1453.0 1129.0 1344.0 1258.0 1205.0 921.0 1632.0 1299.0 1091.0 1191.0 1668.0 1449.0 1213.0 1035.0 1332.0 1162.0 1186.0 1283.0 8.0 5.0 5.0 7.0 8.0 5.0 5.0 6.0 6.0 8.0 8.0 6.0 6.0 7.0 7.0 6.0 7.0 8.0 6.0 6.0 8.0 7.0 5.0 8.0 -0.20276316706495834 0.04964722965745621 0.07872902492059129 GO:0003729 mRNA binding molecular_function 27.381573218274866 27.7105818150177 27.251727948204607 26.87263230672945 27.47597941539404 28.09455092055631 26.539711157817912 27.811711930900703 27.24591982003757 27.607780301547407 27.508094399229602 27.87717476705237 27.365011828180503 26.877625214973744 28.077155109033594 28.01864708033556 26.64340427569977 27.914545812224073 27.486933977069558 27.80685168077828 27.54701475727128 27.76983146620782 27.711864641716108 27.64916795754829 27.05321554429646 27.694415563432784 37.0 21.0 45.0 65.0 44.0 38.0 52.0 37.0 48.0 39.0 47.0 30.0 75.0 50.0 44.0 37.0 56.0 44.0 55.0 41.0 48.0 36.0 42.0 46.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA -0.32900859674283467 0.02092133533779403 0.038284203081476474 GO:0003735 structural constituent of ribosome molecular_function 30.72219944187911 30.000755576375308 29.833028427199498 29.31886267066309 29.491762199756412 30.00717137217177 30.159709367118946 29.88042070785069 30.87237671825537 29.45182949085245 30.86217109265323 30.31160360444253 30.809019294098977 29.919462387754912 31.11136617352413 30.28115111649974 30.295933569294128 29.763343829630475 31.57258410182537 30.41064985218218 30.527839099294084 29.887514734232692 31.257019932081903 30.2960022881412 30.575976660398666 30.057423582814298 373.0 127.0 164.0 357.0 392.0 245.0 603.0 235.0 539.0 332.0 443.0 152.0 729.0 229.0 419.0 196.0 631.0 499.0 436.0 147.0 531.0 174.0 407.0 292.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.7214438655038009 0.007911788680711459 0.016907384030013527 GO:0003743 translation initiation factor activity molecular_function 22.76895147662001 23.348432636018266 20.726238414991073 23.11012682630434 22.664236041434666 23.23489841674846 22.24502279243155 23.63048797093256 23.651014188144607 22.94564133341849 22.674413429737932 22.48079351885869 22.541533481532532 24.42306370924429 23.768869623855508 21.94850786334102 21.80802698040161 23.168540008489032 23.395500599384075 22.844414945467246 22.168972158217525 23.451885839854288 22.686796436254745 24.35585286066957 22.510864225674602 22.485621774912886 2.0 5.0 4.0 2.0 5.0 6.0 7.0 5.0 8.0 5.0 8.0 5.0 10.0 3.0 3.0 6.0 14.0 5.0 7.0 4.0 7.0 5.0 4.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5794811593982558 0.11903289845700783 0.16804644488048165 GO:0003746 translation elongation factor activity molecular_function 29.69618070900621 29.103556193071512 29.414559716753164 28.363510338523774 28.83355383458385 29.112739702234748 29.542335871077377 28.92455256934504 29.610355524087176 29.532247756664557 29.480631401870816 29.53272141045073 29.620106524961127 28.462672727678385 29.611277539371308 28.88561835475482 29.17828596346428 28.97548660838737 30.46710660139401 29.37058812378784 30.115382924653183 29.042636264253893 30.153649992069894 28.65738446269821 29.57354975997324 29.69521223132832 117.0 93.0 84.0 139.0 100.0 140.0 141.0 159.0 130.0 143.0 104.0 112.0 135.0 141.0 104.0 147.0 150.0 159.0 135.0 139.0 123.0 132.0 129.0 155.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.5926245159346983 0.005583616806378765 0.012692811975156102 GO:0003755 peptidyl-prolyl cis-trans isomerase activity molecular_function 25.757469951660642 26.38600066637219 26.003220346128536 25.685579670757107 24.94199632186448 26.525176965063448 24.430025272991447 26.59800685875988 26.524689910331922 26.494116821403583 25.53834812094856 26.592994760743213 25.72087294561661 26.38588178691061 25.71842333727312 26.300649902663718 25.220484373064675 25.94373028066175 26.64649685278986 26.40440811995659 25.358087641642488 25.94630290636085 26.03138819037018 26.89082605508634 25.48841736511568 26.450059777709516 25.0 23.0 17.0 26.0 26.0 46.0 59.0 38.0 44.0 34.0 37.0 31.0 56.0 34.0 28.0 33.0 73.0 51.0 34.0 35.0 37.0 39.0 36.0 39.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6285307147115482 0.009374768459434895 0.01937038251220985 GO:0003824 catalytic activity molecular_function 33.853598032242076 33.853868186316255 33.48854038528642 33.00639540227571 33.35738995027741 33.572887243661924 33.56241696332786 33.95215166067422 33.94200641402591 34.030714699830625 34.03210729573873 33.98864016281359 34.03064512837497 33.50063324757614 34.139528354160014 34.01600119765193 33.56148231073437 34.05874919747386 34.19406282442654 34.091134258557055 33.89544534514628 33.63935709325293 33.86139496728601 33.84226651483007 33.9031861184379 34.15889183837082 6875.0 6609.0 6413.0 8375.0 7597.0 10224.0 9034.0 9812.0 9575.0 10053.0 10016.0 8280.0 10023.0 10805.0 7052.0 10631.0 11622.0 11290.0 8026.0 8228.0 9134.0 10005.0 9557.0 10181.0 10.0 11.0 11.0 11.0 11.0 11.0 10.0 12.0 11.0 12.0 12.0 12.0 11.0 12.0 11.0 11.0 11.0 11.0 12.0 11.0 11.0 12.0 12.0 12.0 -0.00027015407417962933 0.7290344895388041 0.7743276961229171 GO:0003872 6-phosphofructokinase activity molecular_function 22.473731006761366 24.078620903368158 22.93462309534664 23.91876337594105 20.674540893738182 23.994388149577865 21.585362773254147 24.86379434679395 22.87225925187775 23.761329222549247 21.882996004321264 23.923015075123335 23.075240763007315 24.19549198304746 22.859083124145993 24.136830580652266 22.99770465031829 23.69978844205981 22.154747281695386 24.10937619806438 20.70977838111284 23.602873194176677 23.12531325703287 23.788024585933773 22.298331800841733 24.440560568564482 2.0 3.0 3.0 3.0 7.0 4.0 11.0 3.0 9.0 3.0 6.0 4.0 10.0 5.0 7.0 4.0 7.0 7.0 5.0 4.0 9.0 4.0 6.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.6048898966067924 3.225641456243767e-05 0.0005099643033035255 GO:0003887 DNA-directed DNA polymerase activity molecular_function 20.654382754790394 21.313316902835048 18.943952507630407 20.595919978411672 20.966365110452106 21.57487444770798 19.44086868120105 20.214679653503364 19.22819562653952 20.649337800200207 21.60236281284411 21.325758950067684 21.488927201596603 21.72770078124816 18.068321952537442 20.775102976237587 21.09103956008433 20.272242489554838 20.26384447969137 19.67421906731264 21.22438307962953 22.078773198087937 17.47060761026688 22.572980879306673 21.69688891500636 21.53190943696116 3.0 6.0 2.0 7.0 5.0 4.0 5.0 7.0 11.0 14.0 12.0 13.0 4.0 9.0 8.0 6.0 3.0 4.0 4.0 5.0 2.0 15.0 13.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6589341480446542 0.11903289845700783 0.16804644488048165 GO:0003899 DNA-directed 5'-3' RNA polymerase activity molecular_function 22.538941865497023 25.243514676032486 22.46902159130663 23.675823132325917 22.01488926794369 26.582226768625496 22.516326986426414 22.039311008681263 22.73799929837482 24.306262425572005 22.82192954049109 24.39634655879271 23.77986051483173 23.64247139123004 22.651484457125807 25.78704098280348 22.151738946496078 26.176183148171074 20.587841404811503 25.38074532860707 22.022620895936733 23.55059671436232 22.176062101619898 26.26059043913945 22.62051645619723 24.95354004683369 9.0 24.0 7.0 41.0 2.0 10.0 7.0 28.0 6.0 16.0 7.0 14.0 6.0 42.0 3.0 47.0 4.0 36.0 7.0 21.0 6.0 35.0 4.0 34.0 NA NA NA NA NA 1.0 NA NA NA NA NA 1.0 NA 1.0 NA NA NA NA NA NA NA 1.0 NA NA -2.7045728105354634 0.0005320055051392492 0.0019244720881558927 GO:0003911 DNA ligase (NAD+) activity molecular_function 21.28942571682166 18.373486592544005 NA 19.053609015587668 NA NA 21.1217857275678 17.561040459302404 22.33816922613481 18.32807642942723 22.004757621793413 16.85893524793492 20.235061724759813 19.5861430502731 20.522927397584397 18.761995562751355 20.16316787724515 17.1769060628175 18.08837984475331 19.387155395274863 NA 16.34736235600107 20.803053039319355 17.997729718925875 22.324417462746744 17.090863305004614 NA 2.0 NA NA 8.0 1.0 16.0 3.0 14.0 1.0 7.0 3.0 8.0 3.0 6.0 2.0 3.0 5.0 NA 1.0 10.0 3.0 13.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.9159391242776564 0.0007226712449063695 0.0024777299825361238 GO:0003916 DNA topoisomerase activity molecular_function 24.019631091653753 22.99607617440823 22.215814797535767 23.17415552980196 21.38745477107417 22.259602457980566 23.77901474674633 22.89422982862845 23.66934734725266 22.52884168579589 23.510643576343107 23.168500921535344 24.08019315248508 23.85034443618671 22.019375503780786 22.840940816984844 22.698902504429785 21.898623380987125 23.5985434500428 23.35495141700488 26.513636874172374 20.506177031662034 23.0097626454724 23.610352945065546 23.395347411870734 23.39859402516093 11.0 16.0 9.0 8.0 29.0 15.0 22.0 15.0 33.0 18.0 38.0 20.0 16.0 9.0 16.0 12.0 38.0 23.0 16.0 8.0 25.0 13.0 33.0 30.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.023554917245523 0.29869755599497017 0.3712893923124729 GO:0003917 DNA topoisomerase type I activity molecular_function 23.272974436176877 20.514814925549928 20.732132361020145 21.317725226454915 20.164704779245863 20.682958801577154 20.82402316689357 18.113962951284574 22.31871510585765 20.8005260416712 22.21917817013107 20.509663517240632 22.092082790146108 21.100406955101487 19.628012085479213 19.086408442568413 21.16974576167431 19.5136904695618 19.51455307116248 21.1299099845221 26.45837064250545 18.59692033168061 21.082160225246245 20.670033408640965 21.905380958035554 21.046159919258766 4.0 3.0 4.0 3.0 7.0 1.0 7.0 4.0 12.0 4.0 9.0 4.0 6.0 1.0 3.0 2.0 6.0 6.0 4.0 2.0 10.0 4.0 13.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.7581595106269496 0.043308142810791976 0.0706517153305469 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity molecular_function 22.71211861238255 22.71137605416118 21.57741485885245 22.70790077902477 20.58036796873832 21.670462477683703 23.579823718946823 22.840749314352788 22.95120540206879 22.01054545612337 22.753006204295676 22.919798165083453 23.66117056590385 23.618156280458173 21.71429635890028 22.72988109059957 22.085206182339462 21.59202576042271 23.51086330213309 23.00774972780345 21.77986765342321 20.05957749506884 22.56976212330749 23.40897691926905 22.760433347380534 23.084192698208017 7.0 13.0 5.0 5.0 22.0 14.0 15.0 11.0 21.0 14.0 29.0 16.0 10.0 8.0 13.0 10.0 32.0 17.0 12.0 6.0 15.0 9.0 20.0 25.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.0007425582213684834 0.9080725552559752 0.9266349541778063 GO:0003922 GMP synthase (glutamine-hydrolyzing) activity molecular_function 21.34443073064234 22.69392663193882 21.893053429923505 21.114510933686944 21.523425222976517 23.045498412667023 20.029289069268998 22.83138808045701 20.194062998848626 22.67358449686257 20.70354365803971 23.302733409249967 22.617573308249888 20.779045508304762 19.34911746160552 23.21514314166924 21.90560137404089 22.904064500662784 20.364067420834342 21.943418213577967 21.882053807578586 22.901314910711807 20.610913606709737 23.02046281754549 21.617625443960492 22.570998489880004 7.0 6.0 9.0 9.0 4.0 16.0 5.0 14.0 5.0 8.0 9.0 4.0 4.0 15.0 8.0 18.0 5.0 8.0 10.0 10.0 5.0 9.0 6.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.3494959012964785 0.0008121171348941295 0.002709952364566507 GO:0003924 GTPase activity molecular_function 30.515338792760524 30.029806258707342 30.08086812836457 28.98897299698357 29.90230170536045 30.06511227210424 30.166819720152034 29.93602221996624 30.646514691187434 30.238216638354373 30.63785187731521 30.28078347088437 30.525339414566 29.39442493455057 30.628406840931483 30.045889792430746 29.986558077278985 30.113285527978004 30.94907482311941 30.083395465780736 31.032371945260444 30.366755020453443 30.6863645578812 29.822565775291725 30.437983388520216 30.435820452944533 281.0 171.0 197.0 298.0 287.0 310.0 372.0 314.0 336.0 318.0 292.0 218.0 382.0 296.0 281.0 305.0 379.0 357.0 305.0 275.0 336.0 268.0 322.0 342.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.4855325340531813 0.009374768459434895 0.01937038251220985 GO:0003938 IMP dehydrogenase activity molecular_function 24.747605071474275 25.92513096354925 24.841680509530665 25.916716869476552 25.482488080517157 25.92846060687248 24.199802917984762 25.92586300891892 23.92241428836415 25.39253036479219 24.45562870042344 25.45805917901135 25.103735717159964 26.02650362772553 24.53788732149409 25.93261773178741 24.315079484869624 25.8322172630863 24.210054257761694 26.55560388070415 25.37187044452633 25.777474746563172 24.79653256899873 25.908461328066235 24.821543085879306 26.105704331823567 24.0 24.0 39.0 46.0 19.0 38.0 27.0 35.0 24.0 35.0 27.0 28.0 31.0 38.0 18.0 36.0 27.0 32.0 35.0 43.0 25.0 33.0 26.0 44.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.177525892074975 5.312128159411724e-05 0.0005099643033035255 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity molecular_function 21.797628251026 23.53192552677495 24.214080303663177 23.089245003438624 22.104808194720007 23.932965390662137 19.66955058283881 23.473324055410146 18.540267759445427 23.45535567193373 20.90284007140296 23.60114112084657 21.62195547306797 23.51958310320806 21.42628044380263 23.626391724383012 20.551278986011027 22.80259070975454 19.729160826062735 23.973844171469537 22.035137193483838 23.56539641156923 19.935819271053788 23.748095310580677 21.440200989549826 23.17395967412629 11.0 8.0 10.0 15.0 3.0 12.0 2.0 13.0 7.0 11.0 8.0 9.0 8.0 11.0 5.0 11.0 6.0 13.0 7.0 12.0 4.0 10.0 9.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.734297275748947 0.0005320055051392492 0.0019244720881558927 GO:0003978 UDP-glucose 4-epimerase activity molecular_function 22.508893424713698 22.308290864415106 20.79355155909452 21.29595119537933 18.910761093744 18.458943564431515 22.817573327501048 23.746062155390987 22.88652013093918 22.782725002427288 23.416975379765606 22.73119843144516 23.09041772616003 22.129336765718346 20.63163937126723 21.587326931482853 21.71168201601072 21.909659293621253 22.131476893103766 22.150885277134986 22.9932953819728 20.464082967183185 23.13229957396112 23.23235662736697 22.70442741269461 21.740494632792686 7.0 9.0 3.0 2.0 8.0 8.0 10.0 11.0 11.0 11.0 8.0 11.0 3.0 6.0 5.0 11.0 11.0 16.0 2.0 6.0 11.0 12.0 7.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.20060256029859147 0.4529203011037244 0.5347630423627702 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity molecular_function 21.747587085099525 22.28720705904892 21.595522056473442 20.89683595289654 20.666710322213962 20.909459085986363 20.759744784768454 22.64030629974761 21.18288959389216 21.411243283256393 21.212548462042705 22.570786576658982 21.369348202099214 22.991102175137573 22.333975731951107 22.737123329032816 21.911812449609428 21.989575374122232 22.585191241150714 22.468197545852647 21.860742045094966 21.188364570803444 22.468526828393067 23.66380424139871 21.51053680716775 19.881848834026226 8.0 3.0 3.0 3.0 3.0 6.0 6.0 5.0 6.0 5.0 4.0 6.0 6.0 8.0 3.0 6.0 7.0 8.0 6.0 4.0 5.0 7.0 4.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5396199739493959 0.29869755599497017 0.3712893923124729 GO:0003986 acetyl-CoA hydrolase activity molecular_function 25.103202642847762 25.072250088218244 24.557694657334533 NA NA NA 25.147023673821288 24.428523345421947 24.54193883057193 26.175041464950667 24.74448804571405 25.503742351785675 25.40661456441193 24.126130314009718 24.39640785020921 22.721633325041733 23.53936946018917 24.26426040951231 25.904521167307315 25.179900544565033 25.41935875485752 23.762049743734845 25.586691796204352 23.98564633766046 25.43161255068728 26.46497689592628 9.0 NA NA NA 8.0 10.0 10.0 15.0 10.0 11.0 13.0 8.0 12.0 10.0 6.0 8.0 10.0 10.0 13.0 10.0 10.0 9.0 10.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.030952554629518403 0.3981027163512083 0.4809604937137541 GO:0003993 acid phosphatase activity molecular_function 21.46981252246836 24.455613827966513 19.24162739848617 22.945834393854287 23.68450673231607 25.92585649942425 NA 24.43144225124341 16.777437713902454 23.00633026908465 NA 20.652308571323065 21.79547816934112 21.640307872036686 21.04477756320053 25.98084525763891 18.685600434252947 22.95980643439305 19.716192574476747 24.04061500226363 22.07396920937382 25.70378228084314 NA 22.778591330431105 18.695699265532703 23.820309722443124 3.0 9.0 15.0 19.0 NA 18.0 1.0 9.0 NA 3.0 6.0 8.0 5.0 24.0 1.0 12.0 3.0 12.0 8.0 22.0 NA 9.0 2.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.9858013054981534 0.0022440334130290284 0.006114746068690453 GO:0003999 adenine phosphoribosyltransferase activity molecular_function 21.879745538839074 23.70970161139081 22.95750402263576 23.77994722797257 22.225690778478125 24.851920089325496 20.835624886529754 23.520948925222626 21.657749762852887 22.515558405604033 21.75846026763464 23.19504139048109 23.31681924196948 24.082189067869486 21.79698518983621 24.17063884698329 19.79669355171966 22.89327286512566 20.671228459533726 23.736989274603037 21.796887449149946 23.71844311808145 21.05397237753961 24.17579383931073 20.95704967480445 20.121319009817928 4.0 8.0 4.0 9.0 3.0 9.0 4.0 6.0 5.0 7.0 7.0 7.0 5.0 9.0 2.0 8.0 4.0 6.0 4.0 8.0 2.0 6.0 3.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.8299560725517345 0.0012242832644312096 0.0037265988146589013 GO:0004003 ATP-dependent DNA helicase activity molecular_function 19.784505405234675 19.50116341890169 19.42503938003768 20.07601839644373 NA 19.486579422429646 19.748245732317905 16.77011023487087 17.952487919804554 16.59041466897012 20.133471333364906 19.371180189646747 20.768036287539875 20.56978642316396 17.415429768018846 19.918877968239183 21.688161636001805 NA 15.458381958310422 18.97532424198165 16.85036078983989 16.041988893851872 18.492748864587874 19.489576874127692 20.03453436189395 20.580028296242237 3.0 5.0 NA 2.0 7.0 1.0 3.0 1.0 7.0 6.0 9.0 13.0 2.0 6.0 3.0 NA 1.0 4.0 1.0 1.0 3.0 4.0 6.0 8.0 NA 1.0 NA NA NA NA NA NA NA 1.0 NA 1.0 NA NA 1.0 NA NA 1.0 NA NA NA 1.0 NA 1.0 0.28334198633298513 0.869603200016942 0.8983980079645228 GO:0004004 ATP-dependent RNA helicase activity molecular_function 21.45483151569506 24.21534425516764 22.863408857417003 23.942477276681704 20.267583941869802 24.49783990650068 20.54153425081164 24.380782713844205 NA 22.985505869337874 20.462847528255153 24.099358669696656 20.677157687863744 24.74447637607964 20.59678005514517 24.235079291160588 22.188397399325765 23.88859763814845 22.472301364759165 23.897298838115677 18.890999577693282 23.37941463459487 20.069352291794203 25.41845999749287 22.038206618152326 23.395486660077648 19.0 32.0 7.0 49.0 4.0 32.0 NA 19.0 11.0 30.0 10.0 35.0 10.0 31.0 3.0 34.0 18.0 31.0 3.0 24.0 5.0 37.0 8.0 25.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.7605127394725812 4.865007418510381e-05 0.0005099643033035255 GO:0004008 copper-exporting ATPase activity molecular_function 21.252580454088054 22.351890772060298 21.32234898868284 19.910286693337152 18.515167906031333 18.81900823931398 NA 21.34522633322445 20.25834402153 22.732767046935223 16.063723418962983 22.83676232966331 22.824187844500127 21.931869728794204 20.87882005412482 22.267561530605725 20.012550850726683 22.61607537656733 20.70447049808121 21.840516300338113 22.4656999694386 21.86359553966021 22.10296586679244 22.57465358025887 19.507463980919987 23.964127417382517 6.0 4.0 2.0 3.0 NA 10.0 3.0 23.0 1.0 14.0 6.0 9.0 5.0 12.0 4.0 14.0 4.0 12.0 8.0 12.0 7.0 14.0 3.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0993103179722432 0.04889984922191003 0.07872902492059129 GO:0004017 adenylate kinase activity molecular_function 25.18851668005917 24.247644392616163 23.04593517378571 21.266201233272806 18.293197875964914 19.693995048654717 26.407249903090328 24.88464703266509 25.197999858105 25.405846446492404 25.982908152850275 24.607844775371213 26.156696047365 23.37629994284956 23.946843354359245 23.689542872222372 25.1893084675453 24.611409272254697 25.62964395269961 24.282846742382503 23.96774351865279 23.393119221071945 24.64001486270964 23.61250539059448 24.948122307137965 25.26632976374534 15.0 5.0 3.0 3.0 25.0 13.0 22.0 12.0 21.0 16.0 26.0 8.0 20.0 11.0 22.0 14.0 21.0 22.0 14.0 9.0 25.0 12.0 22.0 19.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.9408722874430069 0.0940685547103812 0.1379524750629327 GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity molecular_function 23.52248185576339 24.228518788048834 24.021568149732968 23.988556713805885 23.766860076763486 23.00129315881112 22.354839231712933 23.93360165127553 23.225447256040805 23.88565646138693 22.52275731321619 24.48673308960885 24.87959196104095 24.80323897242056 23.198432735962644 24.57579738657721 23.468420929033947 24.195880353129066 22.396247084523267 24.39219383180472 23.05066713986897 24.624809505892266 23.483245447726468 24.21438370891364 23.745081907985398 23.834141425973076 15.0 14.0 15.0 9.0 14.0 20.0 12.0 27.0 13.0 22.0 25.0 17.0 12.0 19.0 21.0 21.0 14.0 25.0 17.0 19.0 20.0 17.0 21.0 25.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7060369322854427 0.005583616806378765 0.012692811975156102 GO:0004019 adenylosuccinate synthase activity molecular_function 20.449692954986343 21.57260176889046 19.72123825615536 19.80282254572929 NA 21.658597270103744 19.47041794712697 21.57544666754752 19.948236560756055 21.76736112758032 19.593568978882708 21.202231976653213 20.090909246581926 21.16926560935649 20.565033342866702 22.240312257976928 20.631145510383906 21.214567971280196 21.263319683397263 22.469503997111293 20.215087632650945 20.768716318698708 20.993472228378987 20.781042978225575 21.09860172832497 22.239597154876385 2.0 2.0 NA 2.0 3.0 3.0 2.0 4.0 2.0 2.0 1.0 3.0 4.0 4.0 3.0 5.0 3.0 5.0 2.0 2.0 3.0 3.0 2.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1229088139041181 0.002563516808869637 0.006910856026093958 GO:0004022 alcohol dehydrogenase (NAD) activity molecular_function 26.933444092220515 26.49016999892572 27.47335819518495 26.12889172846489 28.061894095384076 26.766963892521574 26.24694886129837 26.28900747868564 26.18812379523843 26.44012597443573 26.548197550441685 26.453495755780672 26.67611334783801 25.385464402862528 26.73243188950192 26.94015092158776 26.324448220960768 25.721828309608025 27.373615593703565 27.42859741536972 27.078026879222055 26.43500572547267 26.646162507221398 26.267906354488744 26.484311655107607 26.55383329729531 83.0 54.0 111.0 93.0 47.0 71.0 49.0 58.0 45.0 56.0 62.0 50.0 76.0 86.0 49.0 63.0 99.0 91.0 103.0 75.0 68.0 64.0 62.0 67.0 NA NA NA NA 1.0 NA 1.0 NA 1.0 1.0 1.0 1.0 NA NA 1.0 NA NA NA 1.0 NA 1.0 NA NA NA 0.4432740932947965 0.10596880912720232 0.15148805703407617 GO:0004029 aldehyde dehydrogenase (NAD) activity molecular_function 23.347599397000035 21.06331656093374 22.93096853450295 22.053248123012366 22.70618361849193 20.768758261583802 22.45388617964651 19.652327121019173 24.349419633066177 21.58454809038354 24.194557359258948 21.21229004125725 23.34105455255849 22.502874227579245 23.45999596434065 14.126657746996276 22.851787401409364 15.88259467192715 23.704934297381566 21.72458825710236 21.6549079440736 NA 22.477185009745607 17.818358033846327 23.77759905374981 20.817788081688413 11.0 2.0 7.0 5.0 14.0 5.0 22.0 9.0 20.0 8.0 20.0 9.0 16.0 1.0 8.0 1.0 17.0 8.0 9.0 NA 18.0 1.0 18.0 6.0 2.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 2.0 1.0 NA 1.0 NA 2.0 2.0 2.0 NA 2.0 NA 3.0 2.0 2.2842828360662963 0.00017383318364122836 0.0008236168584623857 GO:0004044 amidophosphoribosyltransferase activity molecular_function 21.527199645583387 19.207744201131533 NA 18.047965042045924 NA 18.197277895649925 22.669747841892338 20.44201823873977 21.015235238361875 17.63721229795548 22.47667899448828 18.465793756926708 20.169719310875067 16.459797659336196 20.59028258318129 19.786251340088047 21.333114687857343 20.012216706343025 19.37166180798161 19.39056752985454 16.01641029842051 19.769028471901173 18.593173325247733 NA 23.11018053443395 18.82960797653795 NA 4.0 NA 2.0 5.0 5.0 4.0 1.0 5.0 3.0 3.0 1.0 5.0 3.0 4.0 2.0 3.0 5.0 1.0 3.0 3.0 NA 7.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.3194554444518545 0.024235695350693053 0.04309296851045225 GO:0004060 arylamine N-acetyltransferase activity molecular_function 23.16594568960949 23.696472585255165 25.046199189855066 21.711649886418556 23.355967379749885 22.882155147496114 18.88915163312424 24.172562869950728 21.307472019736398 24.556843852709346 21.97394437319701 23.560108650110692 22.34527293842906 21.7840787728289 24.841234514978897 24.148579134541567 22.874222956478963 23.779318239836826 21.715996817663626 23.22171954675124 22.54236519284221 24.77373099970122 19.85468863653211 21.998914804016415 22.69201051819471 23.99710244562149 7.0 2.0 11.0 8.0 1.0 9.0 5.0 8.0 3.0 4.0 4.0 4.0 13.0 9.0 3.0 8.0 3.0 5.0 9.0 9.0 3.0 7.0 5.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.530526895645675 0.10596880912720232 0.15148805703407617 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity molecular_function 19.62829727215856 20.64485930619064 NA NA NA NA 18.719071960417367 17.81693253685203 20.845018270377235 20.98939969582741 17.040453053917783 21.45527930583751 18.56552835171008 20.624267279365828 20.814878041732324 21.183841004217047 NA 21.075667667938465 18.306392488035733 19.883214743550912 19.64156741129089 18.69301606999452 19.506281949131814 20.19686273223429 19.466687818183026 21.198283012437827 NA NA NA NA 2.0 3.0 4.0 8.0 2.0 11.0 2.0 7.0 4.0 4.0 NA 3.0 3.0 7.0 4.0 4.0 4.0 3.0 4.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0165620340320807 0.041226833337163676 0.06823751724771919 GO:0004070 aspartate carbamoyltransferase activity molecular_function 26.07909679723847 24.52158815204871 25.605144626267897 NA NA NA 25.014647220987392 22.762762185848004 25.54588118789824 25.245565345827732 26.45858115406547 26.72625310509407 26.79715045999116 24.06679246148025 25.884730841673232 20.92682409815848 25.151891224584066 22.552977778353345 26.489023816383074 24.46515891654709 26.450980068439204 23.769619096404906 26.85846109736238 16.57072910900034 24.848488174932793 24.22778795649372 13.0 NA NA NA 12.0 10.0 22.0 16.0 16.0 17.0 19.0 11.0 27.0 7.0 17.0 11.0 20.0 11.0 25.0 13.0 24.0 1.0 17.0 21.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.5575086451897597 0.0024620350685983132 0.006679608186110206 GO:0004072 aspartate kinase activity molecular_function 22.295784841430873 22.67436847606741 21.484768877797027 21.63939059116184 20.87066258727645 21.126892876453585 21.89612537832703 22.97645129643252 19.266913453478654 23.030188977035642 20.439030167513945 22.73882859769093 22.39432879871953 22.778549526603108 24.87556257567512 22.305861942720046 19.96022542832561 22.445990045705848 21.87520441644741 23.16654142936143 21.76313207761708 21.844403904080053 22.06741666109345 23.10935531964473 20.82857453951185 23.34110099613157 6.0 7.0 3.0 6.0 7.0 15.0 3.0 13.0 7.0 16.0 12.0 11.0 5.0 11.0 6.0 13.0 13.0 14.0 12.0 7.0 14.0 11.0 10.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.3785836346365379 0.011074437676156606 0.022291771322328135 GO:0004073 aspartate-semialdehyde dehydrogenase activity molecular_function 21.207037425698296 22.750412860009856 20.995294589147484 20.873070949520333 NA 21.671214115431496 19.85243420004245 21.934986787138527 20.66292514812389 23.052646387078518 21.12865544275407 23.624266892761263 22.368826529508578 23.499478345676327 20.25240705457813 22.675556797644237 21.49866754741949 22.251709462509236 22.125819435296997 22.775514431112114 19.756019436082834 21.40813060185476 21.60424742778346 23.586803864734375 20.375545490467367 22.868467723928557 6.0 2.0 NA 4.0 3.0 6.0 5.0 8.0 4.0 6.0 5.0 7.0 6.0 9.0 4.0 6.0 6.0 7.0 4.0 5.0 5.0 5.0 4.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.5433754343115602 0.0016962207449685985 0.0049575725754585735 GO:0004084 branched-chain-amino-acid transaminase activity molecular_function 21.64254677697177 24.275106948411192 20.857386200255398 21.070637652721718 20.599954184763018 21.870017459782968 20.776167188466736 24.28585984299353 20.383875883121988 25.281885615700922 21.769385516595978 24.38041231726949 22.68223912034738 23.80105179241968 20.86907738768701 23.62004460775324 22.1359474864647 24.243716791786188 21.11605519217158 24.244577243461585 22.338344550337315 23.382380600523657 21.98087982226945 24.987588968184166 21.963361995858488 25.359414651542696 10.0 3.0 6.0 3.0 7.0 21.0 4.0 26.0 16.0 22.0 15.0 11.0 9.0 15.0 13.0 26.0 16.0 16.0 14.0 18.0 10.0 16.0 12.0 20.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -2.6325601714394224 0.0005320055051392492 0.0019244720881558927 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity molecular_function 22.012068309788155 23.06071345086803 18.012081035394626 21.2118077861278 16.656484777451478 20.819907420650686 22.25203677947117 22.619039532036137 21.922332698769026 22.48962568875202 22.76696468718896 22.72768652315773 21.81629995395608 23.38627347891443 22.269985016777916 24.166991470658818 23.04736805349425 23.98213768934228 20.41961936006771 21.23292357508747 20.011797738991007 21.07279812417553 19.68492977783856 24.53838587123104 23.692692245908304 22.52276941476121 1.0 11.0 1.0 6.0 5.0 23.0 7.0 17.0 8.0 12.0 10.0 13.0 12.0 19.0 9.0 25.0 7.0 10.0 3.0 11.0 2.0 20.0 8.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0486451410798736 0.0734883472918226 0.11239394291690516 GO:0004124 cysteine synthase activity molecular_function 21.781823120858466 22.385365284797782 NA 23.574255840877573 NA 19.63613718720489 21.89693646781361 23.13120980461772 19.300817901246354 20.130022005271147 20.492018382830306 22.514823784597827 21.00561954882139 22.703553317164197 24.055792485860373 22.028226870463328 21.19968654882986 22.77643680691472 21.754194966945402 21.176846893904237 20.086099462685638 21.768296776163808 20.825994944143407 22.335150223378445 20.58138017923027 22.650644369441338 NA 3.0 NA 1.0 3.0 4.0 2.0 3.0 2.0 3.0 4.0 5.0 4.0 5.0 2.0 3.0 5.0 5.0 1.0 4.0 3.0 4.0 3.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6035421639393164 0.0558501136757434 0.08834086421714546 GO:0004148 dihydrolipoyl dehydrogenase activity molecular_function 23.95887198075017 24.398370818366512 23.468442252929467 23.85179571825325 22.81391323803237 25.550704064942646 24.350462963390946 24.86284948064613 21.943847968975398 23.502890504042124 23.38549872443954 23.866724762386408 24.43537815126463 24.26908990734005 22.393805404331363 24.23545620349257 23.10745233168633 23.91061206792435 24.95586132809696 24.23008013236456 24.94640986224432 23.008767463236907 24.542253004306588 25.074960090992022 23.71441697534704 24.52654972415983 13.0 13.0 8.0 26.0 13.0 17.0 14.0 20.0 19.0 24.0 23.0 12.0 11.0 16.0 13.0 13.0 28.0 25.0 22.0 16.0 23.0 18.0 15.0 24.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4394988376163411 0.2040238704744366 0.2705863871967023 GO:0004151 dihydroorotase activity molecular_function 20.13646175681958 21.283127452492927 20.8699758074241 21.02443411085388 NA 15.473956809449325 19.565923515197845 20.634766941804934 16.59244261054773 22.417313441180735 18.26660882577001 22.36798435064303 21.46457564197565 20.77532646670165 17.330862315959372 18.695954360761327 20.78557827243827 19.913238457338952 20.69941488116709 19.473965678137752 19.211645523761607 19.2688020303852 19.48414029412153 21.082200210743906 20.664875805537907 23.103898685630288 4.0 2.0 NA 1.0 2.0 3.0 1.0 11.0 2.0 9.0 5.0 6.0 1.0 1.0 5.0 4.0 4.0 3.0 2.0 1.0 3.0 5.0 6.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1466656956733488 0.26793808403417974 0.34296074756375006 GO:0004155 6,7-dihydropteridine reductase activity molecular_function 21.489636387146163 23.58195761642974 23.12453896349801 23.21037467436421 23.649175712500845 23.38272749905434 15.547760569190768 24.42466811070344 20.862262201502983 23.79129949978477 20.688167179091128 22.80387080510097 20.840850655332943 22.554409349011912 19.206825146752788 23.47393375642745 19.655387114483702 23.064725304153658 20.851843561672663 23.58547435233091 21.058964824550763 22.948497936223607 17.675928791092808 24.605031010464863 20.775924262689763 23.62026597983213 2.0 5.0 3.0 13.0 1.0 14.0 3.0 15.0 3.0 7.0 4.0 3.0 2.0 10.0 3.0 10.0 5.0 10.0 3.0 5.0 2.0 7.0 3.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.092321229283577 0.0006583371695572323 0.0022696264851033866 GO:0004160 dihydroxy-acid dehydratase activity molecular_function 21.297484024045954 24.235165209083465 23.711195657824607 21.539582027015786 19.272105653565507 23.61125034067416 17.963391574204646 23.53519743994131 NA 23.244166228082804 21.840776993242354 25.570899710735326 20.710487910023307 21.744038277202762 21.688376482358027 25.153912240933447 20.5606344150988 25.17647082917445 18.87832214686837 22.81555735586898 19.47881281412633 22.87181288396455 20.61922845819533 24.95606410610734 18.954648403813373 24.442641722067556 6.0 6.0 3.0 10.0 2.0 14.0 NA 14.0 7.0 12.0 6.0 7.0 4.0 22.0 4.0 27.0 3.0 6.0 2.0 10.0 7.0 18.0 4.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.937681185037512 0.0005677687997916827 0.00204200421366 GO:0004170 dUTP diphosphatase activity molecular_function 21.020768686558405 22.405928322273507 17.31867182816356 22.189102220522546 22.485228952314134 22.830087076714285 20.625647451781823 23.03725786080119 21.565747118825 21.426105267840658 21.366800243075627 21.269923713595396 21.742977680868808 22.747332658259 21.070484429316085 21.898604984196762 21.05241622745523 21.722189620180373 19.39712659678102 22.446816815218224 19.055060571376764 21.8440647354619 19.567677315597013 23.834344286970076 21.04985705805861 20.64936516509291 3.0 7.0 10.0 7.0 4.0 6.0 4.0 5.0 3.0 3.0 3.0 6.0 7.0 7.0 5.0 8.0 3.0 9.0 3.0 7.0 4.0 10.0 4.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.3851596357151017 0.00268017172806849 0.006910856026093958 GO:0004175 endopeptidase activity molecular_function 26.339719184560426 26.321178166813716 27.506341453721266 26.189905602807606 26.51168254725237 25.663895140454553 25.207900627720303 26.393263711862488 26.481035982955042 26.199510615376052 26.332460993584363 26.612711869536657 25.893568072299967 26.17736355789075 26.45888669302445 25.90905256261617 25.552491396527497 26.423499172022467 27.033759223224425 26.81658810263491 25.631149226377936 26.051516039906172 25.167603471833647 26.89046370366745 26.34152768337397 26.00902989504065 54.0 53.0 66.0 63.0 46.0 82.0 63.0 77.0 57.0 63.0 66.0 84.0 96.0 80.0 50.0 114.0 115.0 100.0 43.0 63.0 61.0 115.0 56.0 93.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 5.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 0.018541017746709798 0.7290344895388041 0.7743276961229171 GO:0004177 aminopeptidase activity molecular_function 25.025822651304512 26.56077606285747 25.982293240562896 25.941185255217324 25.693360285250925 26.41176623124704 24.92228164726137 26.51820160149512 25.163292731859478 26.162617039512824 25.3806270019997 26.94602860404485 25.09752890867432 26.040420990375534 24.60225360152709 26.882604981049038 24.60144321565269 26.87304507971391 24.09241672034289 26.60899364935964 23.21232424896604 26.114918837357425 24.240002189809108 27.405962402687784 25.326488043788398 25.95701312172396 37.0 58.0 35.0 97.0 42.0 80.0 53.0 86.0 59.0 78.0 47.0 45.0 49.0 115.0 32.0 110.0 42.0 90.0 30.0 91.0 44.0 99.0 55.0 84.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 3.0 1.0 1.0 2.0 2.0 3.0 2.0 -1.5349534115529586 5.312128159411724e-05 0.0005099643033035255 GO:0004180 carboxypeptidase activity molecular_function 22.11501595728244 25.48736972582294 24.392888900536327 24.30705669308508 23.06123895303815 23.68982213070868 18.515722510126164 23.083688218913213 22.344019711545787 22.692729866953467 20.193550814530198 24.32919985692562 21.024818244012785 25.080394585379683 20.218077472182767 26.77072544683444 21.511436735550195 27.79570621507273 22.57154272428607 21.125165555548232 21.26885608955368 23.668008790361142 19.734263625581182 26.36489627957989 19.70533416907589 23.00814111588157 24.0 25.0 14.0 32.0 3.0 21.0 8.0 12.0 7.0 25.0 8.0 22.0 4.0 35.0 8.0 32.0 14.0 6.0 7.0 12.0 2.0 31.0 5.0 20.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 -3.372353768540499 0.0009986863791802587 0.0031633517797384847 GO:0004181 metallocarboxypeptidase activity molecular_function 21.66214851610627 20.503382871428162 24.20031258912257 20.880162482375894 22.889515304702112 21.792211974468227 17.815597619465393 16.089285219144667 22.26643518779952 16.448500123956865 19.52705666925651 21.218577159093325 20.46160674558418 20.08149430074861 17.32804780596965 20.626033140764086 20.434345678208608 NA 20.147672296245734 NA 20.88768102982177 19.23150094097109 16.145075986340327 19.0097993506571 19.059148969755725 21.433217533829733 16.0 4.0 9.0 4.0 2.0 1.0 7.0 1.0 5.0 7.0 4.0 3.0 2.0 5.0 4.0 NA 3.0 NA 4.0 2.0 1.0 2.0 3.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA 1.0 NA NA 1.158765644678109 0.7919708776587341 0.8333723906560709 GO:0004197 cysteine-type endopeptidase activity molecular_function 25.13901511923553 25.27445418046279 27.298277684519487 25.510126629306985 25.656189004977 23.854600932387985 23.664041666548147 25.59488458847757 24.450901810402087 25.543312878927974 25.317343161142663 26.126803688130387 23.964711166530357 24.51123052092256 24.80520637105926 24.23864304378769 24.52739191508913 25.053553066314567 24.909497360250782 25.62879660754694 24.78664454298469 25.46199587495905 22.2856056515577 25.41111879731 23.51498704179749 24.836662886240077 11.0 13.0 10.0 15.0 4.0 17.0 9.0 17.0 8.0 15.0 6.0 14.0 12.0 19.0 7.0 20.0 7.0 15.0 9.0 16.0 6.0 18.0 6.0 16.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 NA NA -0.13543906122725957 0.10596880912720232 0.15148805703407617 GO:0004222 metalloendopeptidase activity molecular_function 22.82712004894525 24.31143291624793 22.273559717583872 24.232444620658736 23.47271418119297 24.083917162031952 22.215046348498863 24.530809085027233 23.024196564510003 23.866644901474714 22.697662743367466 23.502379520378362 23.17570606948275 25.021970317234878 23.385014247926602 24.156508557397355 22.72594450850989 23.83869248103539 23.136741395097154 25.10595665667632 21.568308405284867 23.8424955723597 21.593182683660558 24.490472743894315 23.182526746575576 24.135470514465656 15.0 26.0 18.0 22.0 15.0 39.0 23.0 28.0 14.0 14.0 22.0 38.0 27.0 34.0 18.0 35.0 34.0 33.0 9.0 31.0 14.0 33.0 18.0 30.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.4843128673026804 3.225641456243767e-05 0.0005099643033035255 GO:0004252 serine-type endopeptidase activity molecular_function 25.267476884367696 24.419419390183243 24.291541258629852 23.10991396135403 24.89309854294981 24.268659255012803 24.295804657019 23.656271166306485 25.89049777515219 23.61710297480559 25.076466496510896 24.05763957742949 25.1209724390628 24.09397417194775 25.6311466167574 24.547109190296155 24.10891302521873 25.25993922949207 26.5074063238416 24.84797961350989 24.247551930604352 22.982427363284025 24.80989219954589 25.744483652451525 25.92085158072056 24.18998184227648 28.0 14.0 38.0 26.0 27.0 26.0 31.0 32.0 34.0 34.0 38.0 32.0 57.0 27.0 25.0 59.0 71.0 52.0 25.0 16.0 41.0 64.0 32.0 47.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.8480574941844523 0.013042519940568903 0.025877686622941164 GO:0004300 enoyl-CoA hydratase activity molecular_function 21.083400671114894 21.983481738449 23.818793571824628 20.269868949495386 21.454194091901176 21.948734881807667 18.524031987707648 NA 16.099386048960213 20.127641623870076 19.55524163966037 23.4088087064608 19.928190605721266 20.50684647385815 21.314106482863075 23.226809004136143 21.20840761547664 22.795396413155714 17.338179665764752 17.675858074809835 19.88777686352337 20.216068367670747 16.725684789362905 22.33471778963172 18.94224572576648 21.37235483916815 8.0 2.0 4.0 7.0 1.0 NA 1.0 5.0 3.0 14.0 2.0 5.0 4.0 5.0 4.0 5.0 1.0 1.0 3.0 3.0 1.0 4.0 2.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9000810673341064 0.036388866200708525 0.0618709877636025 GO:0004308 exo-alpha-sialidase activity molecular_function 20.41725169029957 21.394231540604892 20.654889842477818 19.15234145690533 19.774047326158907 NA NA 21.89331523192368 NA 22.185418970356327 15.841625450440304 21.136179101162988 NA 19.459237614672446 22.040587136497816 22.053579819634024 19.307121242128364 22.25724309370009 21.692871667902264 16.032800505292634 19.384554318515434 21.681992582608924 19.638179104487094 15.94527816203512 17.124325807074214 22.30563674270239 12.0 2.0 2.0 NA NA 20.0 NA 17.0 3.0 8.0 NA 4.0 13.0 21.0 4.0 21.0 12.0 3.0 6.0 15.0 8.0 1.0 3.0 1.0 3.0 2.0 2.0 NA NA 3.0 NA 3.0 3.0 3.0 NA 2.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 NA 3.0 NA -0.9769798503053231 0.20999967175560952 0.2779210926309657 GO:0004312 fatty acid synthase activity molecular_function 25.38753888757465 24.617013442273173 23.7627836675246 23.127139189569675 23.574698184001388 23.99678777660212 25.016361524033734 24.63224556217948 26.06232892866727 25.51338461252636 25.646096661934305 25.293352881913872 26.004717560659746 24.420354697827893 25.508639836864553 24.33120037252327 25.126219123053122 24.77954637526107 25.61309634205768 25.04458524436385 24.48587304440523 22.81415366106009 25.93689696813387 23.561487736617302 25.65251257315217 25.293750979767466 25.0 8.0 14.0 12.0 32.0 32.0 49.0 41.0 41.0 40.0 45.0 26.0 47.0 27.0 43.0 35.0 62.0 45.0 32.0 19.0 51.0 23.0 45.0 31.0 4.0 2.0 4.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 5.0 4.0 4.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 4.0 0.7705254453014767 0.02092133533779403 0.038284203081476474 GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity molecular_function 23.59229369429153 23.37377102861195 21.81113965743314 NA 21.627000454949545 17.944837876861587 23.322892931077927 23.799755087480396 23.59242275860486 24.903408633910626 23.63867196640862 24.157311979102808 24.253132351234626 22.76621981602518 23.63207597782558 21.51870384965805 23.24320255492914 23.618200767928954 24.04305404944493 23.339437976470517 23.534211432057706 21.449777690513155 24.230536872308537 21.13511356848423 23.98490531731312 23.91535564236037 8.0 NA 3.0 2.0 11.0 14.0 17.0 18.0 13.0 15.0 19.0 11.0 15.0 7.0 16.0 14.0 22.0 17.0 13.0 7.0 20.0 9.0 19.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.21852266567957912 0.3247557654026184 0.4012639356708831 GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity molecular_function 24.00812425674852 23.128247177771183 21.584303134382786 22.97527355628008 22.70011635076511 23.91805944734332 23.800583527433858 23.022518126977843 24.87350945643356 22.42184865310628 23.986679547078882 22.9691927550344 24.612246309750176 23.160652146600732 24.04660669210713 23.09869598852959 23.8762921487992 23.4015298900954 24.18571927355392 23.973110800294947 22.68697209427154 20.09643935178468 24.57606875244679 22.172798076694583 24.34531688096332 23.49440441752266 5.0 6.0 7.0 8.0 13.0 8.0 14.0 9.0 10.0 9.0 12.0 9.0 15.0 7.0 12.0 8.0 19.0 14.0 6.0 4.0 14.0 5.0 11.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.8798770789773371 0.024343383653741054 0.04309296851045225 GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity molecular_function 23.667300263841767 22.592354608210268 22.76944946092145 19.803973363552448 21.13194087136376 19.280286060501254 23.074478372753678 21.458024621493767 24.617416824775173 23.37717726996241 24.05218844795024 23.75928629521237 24.36308207294817 22.50246716479247 23.985607300321327 23.008243671977144 23.42597379843491 22.130652298342085 23.34092771852345 22.84352407599289 22.07833264374336 21.69254970425487 24.212510176406283 22.350778219727573 23.789255700743624 23.40711462860434 10.0 2.0 2.0 2.0 8.0 10.0 16.0 14.0 15.0 16.0 13.0 6.0 14.0 10.0 14.0 12.0 14.0 14.0 12.0 8.0 16.0 9.0 14.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.074945655631499 0.01531382171343201 0.02967647437634029 GO:0004329 formate-tetrahydrofolate ligase activity molecular_function 25.921864406991528 22.886878959559716 23.11938665379716 22.31606724550499 23.44824602553237 21.824067896258093 25.801210619644714 22.72235037983958 26.556993657176704 22.548615194971017 26.769842602828806 22.980751554158047 25.672539896931138 20.408736507742187 26.270172252318662 21.639313184808262 26.115886189221698 22.950277986036085 26.05731697702932 25.061957969156275 23.067924678194665 21.882983649189953 26.587153596122853 19.012469751870498 26.325513167633535 23.340128098453608 5.0 4.0 8.0 5.0 19.0 4.0 22.0 4.0 20.0 4.0 21.0 2.0 30.0 3.0 15.0 5.0 18.0 17.0 13.0 3.0 18.0 2.0 22.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.0349854474318114 0.00010962068302139599 0.000648372570666835 GO:0004332 fructose-bisphosphate aldolase activity molecular_function 26.661414462931017 27.824032109253373 27.04070818005352 26.30326133629341 25.958363339178966 27.423216513243045 25.957484247250232 28.0770539821325 25.62986045416533 27.237397159619068 27.09768657231166 27.952223774336723 26.26614172772337 27.05158159340091 28.299350399813147 28.765782272483808 26.340218567881394 28.90858516037059 26.955648299988408 27.47707054298641 25.749929771596406 27.51340686675725 26.04074467656034 27.85528337029632 25.79272735972185 27.313834571877212 15.0 19.0 12.0 24.0 24.0 34.0 27.0 38.0 28.0 29.0 19.0 25.0 36.0 29.0 25.0 34.0 37.0 21.0 23.0 27.0 24.0 24.0 22.0 30.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1626176463223565 0.0009986863791802587 0.0031633517797384847 GO:0004333 fumarate hydratase activity molecular_function 26.073088076141982 26.606877251501174 25.402579038504072 NA 18.52550393905205 NA 25.418836097048263 27.37218003798629 25.1330607376543 27.55872570767585 24.804403600037016 26.384524183022044 25.90358259238805 24.129864605561426 25.95218808260721 25.837232453450106 27.161776059714818 26.975913287850624 26.45929446935793 25.830903234972137 27.157989216120487 26.00535550618405 26.697914935985487 23.43716786236578 25.90322894579002 27.675142075564818 8.0 NA 2.0 NA 9.0 8.0 7.0 8.0 9.0 8.0 6.0 6.0 8.0 6.0 9.0 7.0 26.0 7.0 10.0 7.0 9.0 6.0 7.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5337891753591926 0.35593807492841845 0.43337630976650365 GO:0004340 glucokinase activity molecular_function 23.259195132321896 24.69135135102785 24.952654409328407 23.986665927541136 25.07448580171551 25.46622931827293 21.15373136155889 24.14111338899725 19.9983472301852 24.211615415010552 22.515607326031702 24.738163180834068 22.838593710674786 24.92045583189791 23.592786951510462 25.25906085314449 21.31931603236168 24.91153775884497 21.967695496920232 24.17386399846133 23.54820294070045 24.868277677588853 19.44304543057472 24.8732853906355 21.716357959683556 23.57030021833093 13.0 22.0 21.0 18.0 7.0 24.0 5.0 26.0 11.0 20.0 10.0 21.0 20.0 25.0 7.0 25.0 17.0 19.0 17.0 25.0 4.0 21.0 10.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.4321562187059556 0.0032349119169146935 0.007931571851295751 GO:0004347 glucose-6-phosphate isomerase activity molecular_function 24.268403746858073 24.902271198394647 25.10922113064069 20.45596113534043 25.08269568022706 25.689769210006904 23.647876119892373 25.265839415220103 23.48999971707397 24.971695526647874 24.16732479328061 25.83420746992541 23.15203954151234 24.94981978579633 21.60441405562393 25.11727538343611 24.049902977700324 23.45383551256597 25.164168276113553 25.29729313458346 24.53590276952352 25.06234057737537 23.25375077280133 24.436176112070278 24.586822166192732 22.999648889650025 7.0 2.0 4.0 4.0 11.0 14.0 14.0 7.0 13.0 7.0 7.0 3.0 9.0 6.0 4.0 7.0 25.0 13.0 8.0 5.0 12.0 5.0 9.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6338674515365739 0.14891467317876572 0.20512749682902828 GO:0004355 glutamate synthase (NADPH) activity molecular_function 23.90774579545162 23.01047085537374 23.988378358538927 NA NA NA 22.536741259880586 22.70488893562592 23.321236680137467 24.22576696888717 22.92837970891036 24.606970623059567 24.209022033677826 20.876011756468774 24.07754735352837 20.206040617014533 21.99468183651207 21.56627947231576 23.7768487886203 22.85551445844025 24.87040409258141 22.199298207002336 25.083154643396483 19.711761305096267 23.262414453207178 23.63041370186685 7.0 NA NA NA 5.0 15.0 9.0 14.0 6.0 14.0 9.0 7.0 13.0 6.0 7.0 10.0 11.0 9.0 12.0 8.0 13.0 5.0 9.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.8972749400778817 0.05726498942466171 0.08978229497735907 GO:0004356 glutamate-ammonia ligase activity molecular_function 20.816871579504745 22.106286179143012 20.589570465993045 NA 18.951320643545355 NA 19.835022504442726 21.28384064297124 19.07517576179307 22.061937293200174 22.13838925917103 22.362709283257395 21.395883869771204 22.385609565868755 19.687719247976172 21.345730793630953 17.870889476764752 22.36570582186728 19.31481965823432 20.956189419365998 22.470516322482734 21.347198638281537 21.638330511406338 22.9372288789957 18.628608605994287 22.64141608169493 7.0 NA 2.0 NA 2.0 6.0 3.0 8.0 3.0 6.0 4.0 6.0 3.0 4.0 3.0 6.0 2.0 5.0 7.0 4.0 8.0 9.0 2.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.2894145996382669 0.010123449840655436 0.020813946295120237 GO:0004370 glycerol kinase activity molecular_function 25.188925156696826 22.34286129554204 22.198743037006697 21.729977553507663 20.42044685976462 20.645154327840128 24.605035800004515 20.123171915573057 25.262303248553337 17.23855670669803 25.44831162180107 25.23217449598191 25.94720484930362 20.603892960581945 24.78105665246161 18.23426718385396 22.01891302912467 20.643957086041514 27.122107994509445 23.322730859002036 25.991074924933177 18.988652635878328 23.912464522900944 16.886367989739707 23.82810672284186 21.668204934798737 6.0 6.0 3.0 4.0 14.0 6.0 20.0 2.0 16.0 17.0 22.0 7.0 24.0 1.0 9.0 4.0 22.0 19.0 17.0 2.0 15.0 1.0 14.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.8460638611547857 0.0009986863791802587 0.0031633517797384847 GO:0004371 glycerone kinase activity molecular_function 23.515980377276115 24.44160348614676 23.63825758337921 23.778978193214368 23.756577672964703 23.972770543597804 23.270502129449405 24.479562350205263 24.612614403939233 24.373287955262604 23.147466939094205 24.063555930817515 23.132453300507628 25.29987067378742 24.276420502810375 24.799861525662322 23.22746571278431 23.89611673399219 23.675557996116204 24.40991773606421 21.761696554670173 24.53097305695477 21.113970891699182 24.938413537312 23.64229833919745 23.84795571961093 9.0 11.0 7.0 11.0 14.0 12.0 17.0 10.0 19.0 8.0 12.0 6.0 25.0 14.0 13.0 15.0 20.0 16.0 4.0 15.0 8.0 12.0 17.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9256231088706457 0.0008121171348941295 0.002709952364566507 GO:0004372 glycine hydroxymethyltransferase activity molecular_function 23.72924010653247 23.25198148579598 22.497870442452136 22.097410575440605 21.40931797755942 22.033168333086792 23.952893215398927 22.61893922483452 21.920788620517982 23.29525771139891 23.65706746172714 23.933001995436488 23.79790323926485 23.69827688866157 23.0202843372497 23.529220351510354 22.459031033568625 23.069144701697606 25.11938541269609 23.552209126144827 24.53120915258101 22.481428856086374 24.47999992826569 23.679981061561225 23.48985287966033 23.54399349413672 12.0 6.0 5.0 8.0 15.0 11.0 11.0 16.0 13.0 18.0 14.0 9.0 15.0 11.0 13.0 12.0 22.0 16.0 20.0 8.0 13.0 9.0 16.0 16.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.47725862073648884 0.5253727863737021 0.6008633207515945 GO:0004373 glycogen (starch) synthase activity molecular_function 21.549353311969 21.46962350676246 23.32158957710733 20.348145031523096 22.389839637093683 20.764195176532265 19.773076221367763 21.94253825077991 20.626478537811142 21.200511041236748 21.466093434982085 21.596070965016647 22.09345984106373 21.493749720787697 21.009185579896574 22.257484347723487 19.38552725426497 20.864061965159216 20.70475423204227 20.681728317680246 21.92599550447714 22.228158225099783 18.71477556456907 21.023767046921407 20.96264521353116 21.747101303235006 4.0 4.0 5.0 3.0 5.0 5.0 2.0 4.0 6.0 4.0 6.0 5.0 6.0 7.0 4.0 7.0 9.0 4.0 5.0 6.0 3.0 4.0 7.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.07972980520654005 0.4884223166225936 0.5675521891480417 GO:0004386 helicase activity molecular_function 24.55489707504239 26.507342679046374 25.835614269829012 26.080760928995794 25.60414579035505 26.73342460904827 23.357886285390233 26.541156804713758 23.11215036788158 25.65383867199481 23.92470417518412 26.509226547931352 24.634477885809392 27.203413191220264 24.51788804788558 26.577440058541807 24.590549215125236 26.074187547005142 24.66469279654091 26.271536322539877 24.173316752285018 26.24495436139456 23.060444330647375 27.312437212645012 24.219970918640204 25.9234728216161 92.0 131.0 64.0 180.0 41.0 130.0 39.0 104.0 85.0 129.0 78.0 167.0 60.0 159.0 42.0 141.0 74.0 131.0 42.0 112.0 34.0 157.0 63.0 138.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.9524456040039837 4.146041132679973e-05 0.0005099643033035255 GO:0004396 hexokinase activity molecular_function 23.380913536558946 24.775137165217892 25.005795905989434 24.2195576837034 25.142862207041397 25.46622931827293 21.38929716173486 24.39320618610209 20.249221007958134 24.264271825861353 22.689562278283137 24.89569568330224 22.908610207276663 24.97354457654213 23.604222585422498 25.270106915805112 21.737205310831925 24.953256352747182 22.06639857883184 24.51224658348917 23.743943323298826 24.9128611707163 20.931303449967466 24.8778747369062 22.260451119789014 23.63342193498632 18.0 26.0 27.0 18.0 9.0 29.0 7.0 29.0 14.0 23.0 12.0 23.0 21.0 26.0 8.0 29.0 19.0 27.0 21.0 28.0 8.0 22.0 17.0 23.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.3942236286589456 0.0032349119169146935 0.007931571851295751 GO:0004397 histidine ammonia-lyase activity molecular_function 26.523984611302037 23.56937454399061 24.50538228297247 23.43448333609713 23.99313757069817 20.256088996836095 26.353174880231446 23.347925688068127 27.02324367337423 22.298629956562152 26.973195317739002 23.868151011177588 26.621490612327214 22.158635069682273 27.00703702047905 20.178784189982764 25.98735798894625 17.651331381192605 26.239650728195173 25.87940251632585 23.76372962789841 23.878382990238872 27.73393856773876 NA 27.08373985208221 23.24856085485495 4.0 4.0 4.0 1.0 19.0 4.0 30.0 4.0 29.0 5.0 28.0 4.0 33.0 3.0 17.0 1.0 21.0 24.0 10.0 3.0 24.0 NA 27.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.954610067311428 0.00017383318364122836 0.0008236168584623857 GO:0004412 homoserine dehydrogenase activity molecular_function 20.20776778508629 20.115070643135358 15.193625643009305 NA NA NA 21.74273235959301 18.798765412333665 16.53962819622708 19.827469603629755 18.4076332522336 21.509129329560146 21.471152098083955 20.266766078338406 18.75266852968221 19.130334960184406 18.103806825180733 18.47185295461399 19.705994588244668 20.384800532469423 20.095177347946095 20.19919686448285 21.641756794162546 19.9504378244265 18.790445858973648 20.19489215778917 1.0 NA NA NA 5.0 2.0 2.0 3.0 3.0 7.0 10.0 4.0 4.0 2.0 5.0 2.0 7.0 3.0 7.0 3.0 14.0 5.0 4.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.09269714195093215 0.2598752364812036 0.333666970296854 GO:0004415 hyalurononglucosaminidase activity molecular_function 20.40986523374811 19.184798620403217 21.97458165959981 NA NA NA 16.063801682702564 17.34622722154791 NA 19.22967434967636 17.885819277681858 17.812683721761648 NA NA 19.45189779418337 19.4366524795938 18.19437159532563 20.610992459443352 21.531216073793736 16.602785697001224 21.055043677264145 19.85342898376959 17.479181652854958 NA 20.69449293129689 18.60230301934646 11.0 NA NA NA 1.0 2.0 NA 3.0 1.0 3.0 NA NA 3.0 3.0 1.0 6.0 10.0 1.0 7.0 4.0 2.0 NA 4.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.225066613344893 0.3359238131517357 0.41263082560370684 GO:0004422 hypoxanthine phosphoribosyltransferase activity molecular_function 21.055096423895183 23.64490880958573 22.72922183250599 23.927992197724123 20.689964873986497 21.473697648467173 20.40429756655107 24.06255122523581 19.74695626488849 23.514752712114657 20.07554207853569 23.01678787089239 20.67080348749221 24.21761125167693 21.99474658662712 23.21606436831802 20.650469268544363 22.970604207392487 21.3456049674809 23.70127655724945 20.68324536984974 23.083285608081752 20.010169419096844 24.813868847012877 20.22952445478365 23.396821195849213 6.0 11.0 2.0 4.0 4.0 11.0 4.0 12.0 4.0 11.0 3.0 10.0 7.0 10.0 5.0 11.0 10.0 13.0 4.0 8.0 4.0 12.0 3.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.5898123856905464 5.312128159411724e-05 0.0005099643033035255 GO:0004427 inorganic diphosphatase activity molecular_function 23.991787913799786 26.073820324370324 25.78094717499661 25.733563888332554 25.12865001307993 26.37088309094287 23.01256803260763 26.07663212692305 22.540071817252173 25.744853446595684 23.26144493682272 26.4905642644975 23.82702949032566 25.260852825213384 23.47740251026967 26.556566978591643 23.13107223551444 25.497402940253878 23.774250637607146 26.064480136322715 24.20356003644034 25.992607983311657 20.989531866218602 26.68796620772654 23.21446304228489 25.642903594956607 13.0 11.0 10.0 15.0 9.0 14.0 8.0 22.0 9.0 14.0 8.0 9.0 8.0 14.0 9.0 16.0 8.0 10.0 8.0 10.0 8.0 11.0 8.0 16.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.0820324105705375 0.00010962068302139599 0.000648372570666835 GO:0004455 ketol-acid reductoisomerase activity molecular_function 20.638768528268265 24.401444696131357 20.26155006336335 22.81673633523675 20.84369996918182 24.97304221420511 18.47274996619061 23.081089978509755 19.73632943870173 24.294885477182607 21.082158855303085 24.411449469834622 20.626221175806645 23.98206871814661 20.827993584301232 25.159793291800646 20.780359784352893 25.19383206098073 21.91049199235446 23.498521241911767 19.91977810254404 23.684728831653302 20.599132700102192 25.039869962388806 20.18535222393738 24.36209325284504 3.0 3.0 2.0 7.0 2.0 9.0 3.0 9.0 6.0 8.0 4.0 5.0 6.0 8.0 6.0 8.0 12.0 6.0 4.0 7.0 5.0 6.0 4.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.7626761678630913 3.225641456243767e-05 0.0005099643033035255 GO:0004459 L-lactate dehydrogenase activity molecular_function 24.251421000632373 27.239574185544843 25.35803746857941 26.37033181524193 25.8319318473797 27.185650281344518 22.84787860407711 27.609706509209534 23.070004543857664 27.58925264358023 23.1755943018929 26.15350132687863 22.46915175114296 26.08377559098751 25.463245543732906 27.662469289712305 22.437800134057774 28.124749617126582 23.304691233661107 26.70927193756545 24.588819478258923 27.252761392341558 23.1995645310769 27.311272186730452 22.952354230276903 27.32703174319669 9.0 16.0 15.0 20.0 9.0 22.0 9.0 24.0 7.0 13.0 10.0 14.0 16.0 22.0 8.0 25.0 10.0 13.0 12.0 23.0 9.0 20.0 11.0 22.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.98815318491247 3.225641456243767e-05 0.0005099643033035255 GO:0004462 lactoylglutathione lyase activity molecular_function 21.543786469200832 22.645134795713467 23.05723874066303 23.34916384117343 22.92763950142568 20.394561629877032 21.46085842997305 21.37401770377017 19.037809705764786 22.023554661974824 21.77169174422232 23.297940426728765 21.5218264815283 22.25719274001122 19.748076194712674 22.934135999469515 19.49801650036013 23.119027812475768 20.79984583381421 23.121326676504182 21.4334521623982 21.959368837071036 20.591620428887172 22.924811095703078 21.005653101521442 22.529163561612616 8.0 6.0 7.0 2.0 3.0 2.0 2.0 4.0 5.0 7.0 5.0 3.0 3.0 5.0 2.0 4.0 4.0 7.0 5.0 5.0 4.0 6.0 3.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1013483265126354 0.007911788680711459 0.016907384030013527 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity molecular_function 22.873679495224337 22.97437200416431 20.871330936052228 22.861182263927226 22.37028776402336 22.463392661183935 22.108579770783944 22.295489588722834 21.809336114627037 23.71493812722753 22.465801469989863 23.01657920836941 23.212040575695468 21.91325195866672 23.915301339529556 22.308047509189482 23.107315417313533 23.279004194155522 23.280184218541113 22.1643193617218 22.89415408798249 20.882169557615686 23.56290788725433 24.662099159619626 22.503687948691354 22.41308926390911 6.0 8.0 9.0 9.0 6.0 10.0 8.0 14.0 9.0 8.0 5.0 3.0 10.0 5.0 10.0 11.0 17.0 11.0 11.0 7.0 11.0 15.0 7.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.1006925089399715 0.6861059569955559 0.7413508522341591 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity molecular_function 20.794675329304958 21.89542745291846 22.50971644553514 20.993163072761032 19.849293579217893 22.04668482410543 19.453714367208345 22.44640433268046 19.553081126362184 21.58135188971601 20.046397572074106 22.44295257886155 21.57599947762937 21.710623497146305 20.324510605849863 22.618204731739173 19.075726123142342 19.01142800078554 19.699569925889186 22.775316143734607 22.221346740516143 21.75652755418593 17.281615931378287 21.357833189700987 20.466168455884414 20.953239353376784 2.0 3.0 5.0 12.0 4.0 10.0 5.0 14.0 5.0 7.0 7.0 7.0 4.0 10.0 4.0 3.0 4.0 10.0 6.0 10.0 2.0 7.0 5.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1007521236135034 0.01531382171343201 0.02967647437634029 GO:0004478 methionine adenosyltransferase activity molecular_function 22.8986885713993 22.5768177842803 20.739342480761987 19.46149873348234 20.15203708012116 16.832641985291207 23.117480880834986 22.604573720048588 23.48501628890396 22.85130425718293 23.193030940564192 22.60304348655572 23.0680695257834 22.51175412069913 22.800514591589714 20.816750063894556 22.94552255391903 23.078016607228626 24.05775517622605 23.65371880714843 20.825175707313587 21.72448135945281 22.760248664934448 23.52824505532646 23.23742060767233 23.015019764270672 6.0 2.0 3.0 1.0 11.0 8.0 15.0 7.0 12.0 6.0 14.0 6.0 12.0 6.0 9.0 9.0 14.0 14.0 5.0 5.0 9.0 6.0 10.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.32187078711899986 0.29869755599497017 0.3712893923124729 GO:0004493 methylmalonyl-CoA epimerase activity molecular_function 25.500403581478643 26.4248440031645 23.310330622764106 NA NA NA 24.400972028651484 26.965815928573804 25.071961325256137 27.521626657162447 24.691994149017766 26.482061708275445 25.802692352866444 24.120307552746173 25.13832950070557 25.83485498496129 25.661919284651642 27.05090496484807 25.687661359982584 25.337746741060013 26.28911287578111 25.63233589789472 26.334633747067013 24.98307939316424 25.78899549892113 27.047339324665646 7.0 NA NA NA 12.0 7.0 7.0 7.0 12.0 8.0 5.0 5.0 9.0 9.0 7.0 7.0 5.0 5.0 10.0 9.0 8.0 7.0 6.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9244404216858584 0.10531581841575224 0.15148805703407617 GO:0004494 methylmalonyl-CoA mutase activity molecular_function 27.91206416203769 28.037462885588063 27.16200378073017 NA NA NA 27.704607718340487 27.99365270765141 27.331548509865137 28.986925501020018 27.221705053934464 28.12489768126157 28.344244922064235 27.02858896193032 27.410489191639385 26.889448298242392 27.94386249707791 28.02109060833329 28.27507493248043 27.679443512896977 28.35408842953352 27.23223306516878 28.570792021994 27.337599146493968 27.83766198455205 29.129160100058463 22.0 NA NA NA 23.0 25.0 22.0 30.0 22.0 22.0 24.0 19.0 25.0 24.0 20.0 23.0 21.0 20.0 30.0 26.0 24.0 20.0 23.0 30.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.12539872355037218 0.8326893587096577 0.8696203511879939 GO:0004497 monooxygenase activity molecular_function 22.97118831510684 23.921389703467703 22.284049765926703 22.70314049559548 23.115316459120816 24.37948054743416 22.352523031120853 24.06133448418853 23.016368227572237 24.032119829227728 23.45980826871605 23.77129270701623 23.420347124773283 23.0837321056522 23.71758910944364 24.752272858069485 21.34359991741396 24.21402554760458 23.150760382720474 24.16588421420963 22.737852979512123 23.76960624520948 22.778006083203223 22.934027957092727 22.91724920884164 23.864344143555044 8.0 5.0 12.0 7.0 11.0 13.0 14.0 9.0 15.0 12.0 13.0 9.0 19.0 12.0 7.0 12.0 13.0 12.0 15.0 8.0 14.0 9.0 11.0 13.0 1.0 1.0 1.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 1.0 2.0 2.0 -0.9502013883608633 0.00268017172806849 0.006910856026093958 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity molecular_function 22.64118505848838 22.81286121315329 22.218546516398806 23.035732356052765 23.5308978655824 22.6736772481107 22.896643507364512 22.605844851740326 21.40177104048967 22.55575415702506 23.1405256782518 23.185715072270433 23.27183860727449 23.61742014048901 22.055635428421606 22.42354455660345 22.474341449170016 22.30259431604305 21.64705733926064 22.955936530070304 21.9439226992 22.036439835726934 21.412313986877717 22.798407687982717 23.423110262254163 22.864739799666637 5.0 10.0 12.0 4.0 12.0 10.0 8.0 10.0 10.0 8.0 15.0 11.0 10.0 7.0 8.0 7.0 11.0 13.0 8.0 6.0 10.0 8.0 15.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.1716761546649117 0.3556110610952391 0.43337630976650365 GO:0004516 nicotinate phosphoribosyltransferase activity molecular_function 22.545091218931447 23.573795644816784 22.59955651840518 22.84229286403796 22.889578909420234 23.365191368974337 22.78040575727777 23.52453860434657 21.644427317158627 23.25090479078509 23.12625392863788 23.640894053770786 23.06381635724485 23.510471154569736 22.52823117166987 24.27736814929756 22.498556823562687 23.363378919919235 21.52634292053457 23.28538936227003 21.410374913029173 22.97123224678812 21.317513728264483 24.457553730838896 23.325515062235322 23.494319718740343 10.0 10.0 10.0 9.0 10.0 12.0 11.0 14.0 10.0 11.0 16.0 14.0 13.0 17.0 9.0 11.0 11.0 14.0 8.0 11.0 10.0 15.0 14.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.028704425885337 0.0002755038114342687 0.0011655212090507369 GO:0004518 nuclease activity molecular_function 27.340314104401497 28.26955466934553 27.532934121471005 27.452667136173762 26.985242553752308 27.528878291177012 26.281643763951074 27.863096213375286 27.83416596391031 28.131727879044124 26.978078859839755 27.914248245891073 26.810015929325623 28.196868754661736 26.593516271563114 28.098482887990066 26.53864602062945 27.847738625288024 29.0656659635243 30.109375208303753 28.009945806869716 27.499606156873533 25.063381587164702 28.359368727844128 26.167213534529186 27.46604217079441 212.0 319.0 227.0 315.0 129.0 349.0 116.0 323.0 198.0 343.0 263.0 369.0 190.0 434.0 112.0 394.0 216.0 335.0 197.0 299.0 112.0 449.0 224.0 301.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.9292405649440347 0.007911788680711459 0.016907384030013527 GO:0004519 endonuclease activity molecular_function 25.991332099700905 26.416263170350586 25.77925455212229 25.104108726586198 24.906334131323 25.159825307315298 25.06365738643225 25.584383115664625 26.787953201001248 26.459059819660787 25.72822060704004 25.52317627644147 25.20246358002664 25.778985331447426 24.56287708669063 25.634455373876705 25.322810114863486 25.548397187031213 27.92915287315599 28.93079492492276 26.69312000970236 24.737242725575186 23.541941412179252 26.15898357187488 24.472393481438466 25.13956509675272 42.0 67.0 51.0 70.0 31.0 81.0 34.0 68.0 44.0 78.0 73.0 85.0 36.0 108.0 27.0 96.0 32.0 89.0 35.0 66.0 30.0 112.0 54.0 62.0 3.0 4.0 3.0 4.0 3.0 4.0 2.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 2.0 4.0 3.0 4.0 4.0 4.0 3.0 4.0 3.0 3.0 -0.4249310706496807 0.4884223166225936 0.5675521891480417 GO:0004527 exonuclease activity molecular_function 24.66032024143932 26.743500416668592 25.936667484673627 26.4316127651416 25.74685121963584 26.48512555585618 22.953673759215995 26.71940364654149 22.800642103087878 26.29856411598223 23.500140606768287 26.815421131157603 24.67632094041924 27.044235091534205 25.16993015355553 27.11287054340016 23.33117008262116 26.820396224585892 25.083953688184447 26.68805818453741 25.02999764548853 26.58329080006525 22.69875432263784 27.190951125848606 24.14949684483175 26.40358283622292 105.0 161.0 106.0 149.0 48.0 164.0 35.0 152.0 72.0 153.0 94.0 182.0 86.0 193.0 44.0 183.0 110.0 137.0 84.0 137.0 38.0 207.0 84.0 135.0 5.0 5.0 5.0 5.0 5.0 5.0 4.0 5.0 6.0 5.0 5.0 5.0 5.0 5.0 5.0 4.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 -2.0831801752292733 3.225641456243767e-05 0.0005099643033035255 GO:0004534 5'-3' exoribonuclease activity molecular_function 22.587688497875448 24.9026018790958 24.175636339643997 24.51592596306101 23.80414550301267 24.62391422148469 19.77900392870308 24.968732023928407 20.61321170759752 24.49282493803579 21.144699304418737 24.99452001281898 22.43115020330577 25.158277324527308 23.481590528187656 25.371959369705376 21.220261838168426 25.006154374336447 21.14948861634928 24.839845487532482 23.11354732075921 24.83539256317978 20.393096614720413 25.201854517669982 22.14314118719023 24.487782097477282 27.0 34.0 24.0 34.0 8.0 39.0 7.0 37.0 13.0 33.0 16.0 33.0 22.0 44.0 8.0 44.0 12.0 29.0 21.0 39.0 7.0 42.0 19.0 30.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.3149133812203537 3.225641456243767e-05 0.0005099643033035255 GO:0004536 deoxyribonuclease activity molecular_function 19.986841654834087 21.74913705076272 20.82552241068332 21.284191578486496 20.713032750793072 20.114879535792642 18.922098850891174 22.662632433211517 NA 21.729908863108964 19.937618289626727 21.71518074992758 21.431323409160864 21.644815694500817 17.64528811435411 21.70851950590577 17.521184687074086 21.254007690241693 17.707379642378505 22.25494542601192 20.47823182215007 20.930323665676987 19.07548777985512 22.77907645248418 19.784872369692078 20.646048333667398 3.0 7.0 4.0 7.0 4.0 12.0 NA 10.0 6.0 6.0 11.0 7.0 4.0 11.0 1.0 5.0 1.0 8.0 4.0 6.0 4.0 13.0 5.0 8.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.762295395928632 0.0005677687997916827 0.00204200421366 GO:0004540 ribonuclease activity molecular_function 26.14344517939293 26.7207122006393 26.05617510574356 25.642910671506343 25.363762007799558 25.825747705410272 25.135503353414396 26.020467397897647 26.77700011732393 26.69389714917159 25.84221231143808 26.161834297254725 25.46163402340877 26.3707788171912 25.15432643633457 26.3241766187288 25.35737957466721 25.953023638417463 28.00965402313921 28.97239235698745 26.908053956674728 25.703843763811054 23.79067500957788 26.472948050835576 24.70319509241356 25.668380882687522 59.0 80.0 65.0 85.0 38.0 88.0 39.0 83.0 60.0 96.0 71.0 89.0 58.0 117.0 30.0 104.0 72.0 94.0 72.0 86.0 37.0 110.0 59.0 82.0 4.0 3.0 2.0 3.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 -0.5772670212463709 0.0940685547103812 0.1379524750629327 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds molecular_function 24.639707228040557 25.78544074605546 26.13638059265177 24.625762234114752 24.679317020213624 25.8521104766825 21.944039194296604 25.13858652798007 23.233781689534478 24.59247420308839 23.106421104928856 26.47362349340846 22.929978262789955 24.814554321975585 25.72704173753939 26.282789407555214 22.701895280442013 26.84589714066823 25.451845242336642 24.173269304400037 25.517756057931013 25.87002660135121 23.723553283705296 26.041146666627395 23.512718144684143 26.08287330749227 154.0 120.0 77.0 101.0 11.0 136.0 6.0 106.0 39.0 174.0 29.0 115.0 129.0 239.0 35.0 188.0 99.0 78.0 52.0 107.0 32.0 133.0 39.0 71.0 18.0 16.0 11.0 10.0 5.0 18.0 2.0 17.0 11.0 18.0 6.0 17.0 13.0 17.0 10.0 16.0 11.0 14.0 9.0 14.0 8.0 12.0 6.0 16.0 -1.1457335180149038 0.009374768459434895 0.01937038251220985 GO:0004563 beta-N-acetylhexosaminidase activity molecular_function 20.490110226960763 20.76854802193872 20.029564199774924 13.884608684743526 18.91651353154885 20.959787350726334 NA 20.633217785063586 NA 21.432361203255066 19.54821713489587 17.569111980175062 19.80219605009552 18.869115447249328 23.09750805750809 21.708954660677136 18.30710303856161 21.887288062297444 18.71486869147918 15.052211993630367 20.120425841339745 22.042170073576642 18.20932848217684 NA 18.237775618388525 19.61915080426376 4.0 1.0 2.0 11.0 NA 7.0 NA 10.0 3.0 3.0 1.0 3.0 16.0 16.0 2.0 14.0 3.0 1.0 6.0 19.0 2.0 NA 2.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.2784377949779575 0.5262368666518372 0.6008633207515945 GO:0004585 ornithine carbamoyltransferase activity molecular_function 27.49793240101657 26.788259152364912 27.68413488802528 25.460838523600067 28.04051373614471 26.349528658130307 25.93167125194643 26.631699844126334 26.59277421167354 26.77783072328311 27.74041179678305 28.637347932362925 28.30935201929588 26.932631521909236 27.017128385771777 26.62580428074061 26.937661145129447 26.329734397251894 27.320266382815717 26.54748624006309 28.66379048158445 26.774602981135235 25.4653546514708 24.532089775692945 27.22750082699956 26.047369131184336 29.0 11.0 14.0 18.0 27.0 33.0 30.0 26.0 25.0 24.0 27.0 13.0 34.0 14.0 21.0 20.0 24.0 20.0 34.0 24.0 25.0 8.0 29.0 27.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.7096732486516579 0.02824036873330045 0.04901805310036017 GO:0004586 ornithine decarboxylase activity molecular_function 26.22392891649343 24.489447831847077 25.4922104378231 NA NA 20.292348757572967 25.279226833788172 25.38261569773097 25.668447510631342 25.129200886899614 25.933226198650285 24.997999053446986 27.278173872621828 21.134725097375288 24.36044368478323 22.881180825193823 26.572008426889248 26.135178234218262 26.161230238526226 20.561249741521927 27.48131606108712 22.385182783098813 24.741916114867024 NA 26.294251196013395 24.816539684520997 12.0 NA NA 1.0 15.0 14.0 16.0 23.0 13.0 8.0 15.0 5.0 15.0 8.0 20.0 16.0 6.0 7.0 24.0 10.0 16.0 NA 12.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.7344810846463545 0.004851753319766388 0.011381556659903107 GO:0004588 orotate phosphoribosyltransferase activity molecular_function 22.156639658465767 21.113479755272973 20.99946877211925 NA 16.926044374913847 17.838171159208766 21.829570754029827 20.835150302370952 21.970593725441603 21.35051504853542 22.84203715197061 22.360951684034166 22.97101682000062 22.033156012206344 23.126689459483906 22.26067394455216 22.10349040204392 20.355552112179815 18.740336757749468 19.007138889636213 17.493288744361482 17.776801669351443 21.91855172076457 21.36935542317963 23.52310898055356 19.358175159184423 3.0 NA 1.0 1.0 6.0 7.0 7.0 6.0 10.0 2.0 7.0 4.0 6.0 3.0 6.0 5.0 4.0 2.0 2.0 1.0 9.0 4.0 10.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0431599031927945 0.24225492790512393 0.31691210694506783 GO:0004601 peroxidase activity molecular_function 26.543134230993296 26.420267434909128 25.790380830701146 23.81276952105393 NA 22.666600005305057 26.519845682030123 25.872449293496214 25.96346300696916 27.770542886096287 26.58909397043693 27.26384636659806 26.79900305050373 26.519490190684124 25.772779241776405 25.539557678239888 24.98073266782933 25.07715726039097 27.17580635719953 26.505845992997287 26.79451386777906 25.36393001698584 27.60155545484869 26.67108655709494 26.182296223436445 27.415432288512807 20.0 8.0 NA 8.0 23.0 44.0 45.0 40.0 37.0 35.0 29.0 21.0 30.0 29.0 24.0 30.0 44.0 23.0 35.0 24.0 35.0 27.0 21.0 32.0 2.0 3.0 NA 2.0 3.0 4.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 4.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 0.12286679608416762 0.46018093544712035 0.5412872831649446 GO:0004602 glutathione peroxidase activity molecular_function 20.976857962452485 21.44143428425611 NA 22.541808282368894 NA 20.355577837780274 19.78675044208641 19.734313489159728 21.229354124627076 18.833782640631608 21.870819828260398 20.048924302154752 21.44846877837991 22.540819966058866 21.35956686209736 21.34209442978941 21.497830322651076 20.13611207914612 18.33092034566839 21.029374054907986 16.94993519411291 17.461797225356555 20.466533097855613 23.40626217880502 21.52642505706553 19.8603143314301 NA 2.0 NA 1.0 2.0 2.0 4.0 2.0 4.0 3.0 7.0 5.0 3.0 2.0 3.0 3.0 2.0 4.0 1.0 1.0 5.0 4.0 3.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4645763218036265 0.7919708776587341 0.8333723906560709 GO:0004611 phosphoenolpyruvate carboxykinase activity molecular_function 25.41647479537005 22.402437709132816 23.11669250952445 19.515369330998684 NA NA 25.24580995316989 19.957066778812944 25.002762973066503 22.688408476197072 25.722264849466487 24.583362972598987 24.93303018895463 21.140619356626736 25.87735334352176 14.67918239467548 24.16577279774116 19.744722661854674 25.69838012047296 22.425736118622225 26.837218054452162 NA 25.3704929293369 21.220021950167826 24.54907308324077 23.32115671677488 9.0 2.0 NA NA 21.0 4.0 32.0 12.0 27.0 21.0 27.0 7.0 32.0 1.0 25.0 3.0 27.0 18.0 20.0 NA 27.0 5.0 21.0 15.0 1.0 2.0 NA NA 1.0 2.0 3.0 1.0 2.0 3.0 2.0 2.0 1.0 1.0 4.0 2.0 1.0 1.0 1.0 NA 1.0 2.0 1.0 1.0 3.0140370862372343 0.0003290176868092065 0.0013732912145079923 GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity molecular_function 25.40432962863784 22.176174473182396 23.11669250952445 17.627080466195476 NA NA 25.24580995316989 19.477463970398475 24.962664895308265 22.688408476197072 25.69786087478279 24.307857418443675 24.9221757744282 20.54780551710505 25.87735334352176 14.67918239467548 24.00029045664093 18.539623774198827 25.69838012047296 22.425736118622225 26.837218054452162 NA 25.3704929293369 19.742062515228163 24.54907308324077 23.32115671677488 9.0 1.0 NA NA 21.0 3.0 30.0 12.0 26.0 19.0 26.0 6.0 32.0 1.0 20.0 2.0 27.0 18.0 20.0 NA 27.0 3.0 21.0 15.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.2281551554554433 0.00025051809382168244 0.001120597064836773 GO:0004614 phosphoglucomutase activity molecular_function 22.540970746876827 23.30834145302267 24.25774361125186 21.591646313712662 22.598263460711014 22.88976364088665 19.83431815363324 22.9751676901512 22.13984228418105 23.192517201103765 19.68403416799676 23.738059790426256 19.862621035339124 21.105529382771802 23.750782213688932 23.835905897127127 20.97181876976308 24.29511795525752 23.367921010886178 23.793003285861285 22.332598274335236 23.55320548693273 20.4303922358032 22.820542931997863 22.461957042118726 23.228510666895843 20.0 5.0 8.0 3.0 5.0 7.0 10.0 6.0 3.0 18.0 6.0 5.0 20.0 6.0 4.0 9.0 16.0 13.0 13.0 7.0 7.0 11.0 12.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7673707061458437 0.03266344168491133 0.055917661485280296 GO:0004618 phosphoglycerate kinase activity molecular_function 24.28678500209056 21.87986779557037 25.268929868722363 17.5123205580492 24.78489395679715 22.657490926970873 23.51951140495121 21.47619068251143 22.0197462056182 21.10566700696671 23.445204141581875 20.85365700025773 23.43174939696839 NA 23.34063981374797 20.75459336489341 22.74559905774041 19.839472303177462 26.108791240659947 23.752025473032585 21.888520477388703 22.040406244688587 24.56726266782281 21.068199155977585 24.140281750146407 22.31909419441861 8.0 1.0 6.0 5.0 13.0 10.0 11.0 7.0 12.0 4.0 7.0 NA 13.0 7.0 13.0 4.0 22.0 21.0 7.0 3.0 16.0 4.0 13.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.406917206520191 0.0011065860751634238 0.003496251700769501 GO:0004619 phosphoglycerate mutase activity molecular_function 26.707371363584013 27.795098073677178 27.68392429388608 27.2023321574426 27.580449895270235 27.70110081103787 26.382457189024787 28.007494540459266 25.81025349853141 27.59906981412116 26.22575471746988 28.279863841069265 26.327937097941646 27.263909205079546 26.5504939965043 28.193341305203795 25.99829546956093 28.06950570305443 26.613048109933448 27.9172220754702 27.42655496693761 28.206007240308885 26.158658706461605 26.966735572806787 25.98282914200381 27.415543333310428 38.0 22.0 45.0 54.0 32.0 33.0 42.0 29.0 37.0 37.0 39.0 22.0 50.0 42.0 29.0 36.0 51.0 34.0 47.0 40.0 45.0 36.0 31.0 39.0 2.0 1.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.0877267100931647 0.0006583371695572323 0.0022696264851033866 GO:0004642 phosphoribosylformylglycinamidine synthase activity molecular_function 20.817384002446715 23.171946434116894 17.057942604351563 NA 20.491483338351205 23.2124337724528 20.09238636689795 23.78972117012733 19.855036666834323 22.2555269194758 21.907547996138504 23.28404212776597 22.095481523641304 22.647568677837683 20.12686129451323 24.31954133828029 20.94255647179189 23.93975517948323 19.27600441701755 21.885743526985387 20.644205455922478 23.089032591009783 19.903717355308185 21.75846111672119 21.806103641868916 22.123380736378227 1.0 NA 4.0 17.0 2.0 35.0 2.0 22.0 4.0 19.0 9.0 11.0 3.0 30.0 5.0 33.0 2.0 14.0 7.0 16.0 3.0 11.0 8.0 17.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.3545624316701783 0.00017383318364122836 0.0008236168584623857 GO:0004645 phosphorylase activity molecular_function 22.676822038524065 23.932092366372377 22.321133334330806 23.334363998329984 24.856995783393106 22.78288907470453 20.78918866950812 24.03994798741057 19.61652898032833 24.60749338561867 21.170335894627016 24.00410869783873 21.344841268935077 22.401150003525714 23.46959936934096 23.86670493212076 21.67485900907149 24.16826054769502 22.139290954939845 24.321459686294023 22.027837422501698 22.7644742027314 23.32653058598525 25.004194115145978 21.424743942388425 23.655280245594266 11.0 11.0 13.0 13.0 4.0 16.0 3.0 14.0 6.0 10.0 10.0 6.0 6.0 11.0 5.0 16.0 14.0 9.0 10.0 7.0 14.0 17.0 7.0 9.0 2.0 1.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 1.0 1.0 1.0 2.0 1.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 -1.2552703278483115 0.0018227351663913985 0.005134928866041682 GO:0004654 polyribonucleotide nucleotidyltransferase activity molecular_function 24.250080474212066 22.759778132265357 21.956333620675593 21.53883310803803 23.02786457203418 23.67005680347213 24.162186872796806 22.057720990720874 24.869180592428695 21.699165461694992 24.96442242012916 22.28114502167177 24.75069648667595 23.284766498752607 24.238666351993746 23.12312110516332 23.343145081770416 23.07943859851272 24.85905297469297 22.98031097671501 23.025229428729844 22.252049948457504 24.460463835602315 23.532319740772408 24.51265825260354 21.15890564023705 9.0 7.0 7.0 14.0 23.0 9.0 39.0 8.0 28.0 16.0 18.0 6.0 28.0 17.0 15.0 25.0 43.0 19.0 7.0 8.0 34.0 19.0 24.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.490302341946709 0.0032349119169146935 0.007931571851295751 GO:0004659 prenyltransferase activity molecular_function 24.298025580386724 22.85879596734277 24.225807262236646 20.290997803194692 20.255664029030914 18.733671977668763 16.36433510968338 20.551162714360455 24.591477488605538 18.690164147090304 24.14442189900487 21.13355340808614 25.47846753950523 21.209370385951413 24.5656154224596 22.56235029620121 21.020803454662968 21.8312371394213 18.155871994879 24.763051752147465 24.84683366101282 22.16568113724514 26.202600030467696 23.451892326156106 20.35568938288327 24.754202615736517 2.0 4.0 3.0 2.0 1.0 7.0 6.0 3.0 3.0 8.0 4.0 7.0 1.0 11.0 2.0 12.0 2.0 4.0 3.0 2.0 4.0 9.0 4.0 3.0 NA 1.0 1.0 NA NA 2.0 NA 1.0 1.0 2.0 NA NA NA NA 1.0 1.0 1.0 1.0 NA NA NA 2.0 1.0 NA 1.4392296130439561 0.4529203011037244 0.5347630423627702 GO:0004672 protein kinase activity molecular_function 22.906456383055428 24.36134278540211 22.83824392870028 24.17939225509966 24.12289523149279 24.12431087686621 22.242476425032134 24.589665521579803 22.240367606627746 23.93123086014521 22.45615658042851 24.487387993780608 23.38561421913004 25.312348684687496 22.44512466775191 24.37627963063785 22.634913923932448 23.473904034476327 22.102311541492934 24.336065644751372 22.442683605340076 24.102776000178146 23.40733559929032 24.43391305682909 23.00092887622538 24.22637072146225 15.0 33.0 26.0 29.0 15.0 55.0 16.0 44.0 24.0 41.0 39.0 55.0 19.0 53.0 17.0 47.0 20.0 44.0 15.0 34.0 18.0 47.0 21.0 47.0 3.0 4.0 4.0 3.0 2.0 4.0 4.0 4.0 4.0 5.0 4.0 4.0 4.0 4.0 2.0 4.0 2.0 4.0 2.0 3.0 2.0 4.0 2.0 4.0 -1.4548864023466805 6.784570247173055e-05 0.0005498145239267514 GO:0004674 protein serine/threonine kinase activity molecular_function 22.268912118605403 23.54059296253944 22.63331843459061 23.921818546556235 23.39843504479208 22.512108479168358 22.081233164794284 23.494498933859216 21.614437360467434 22.66030143995704 22.05055818060294 23.487482308711282 22.44065680058849 24.78949900011477 22.28544032074513 23.33145871505008 22.423583372497024 22.456033587803827 20.125957759126305 23.863510280950145 21.95253328141569 23.20276930899197 21.145336749546075 23.58626473849688 22.767010838671368 23.457757022834137 11.0 23.0 17.0 14.0 11.0 27.0 9.0 18.0 16.0 23.0 22.0 27.0 15.0 32.0 14.0 21.0 6.0 23.0 10.0 22.0 10.0 26.0 16.0 22.0 NA 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA NA -1.2716808439340355 0.00034415785384659113 0.0013990521224773477 GO:0004736 pyruvate carboxylase activity molecular_function 23.43171540573509 25.216189989869324 21.937358521642647 NA 21.048697528491388 17.206468051198996 23.28980736497393 25.405768983016948 23.406176841214275 26.48080533938351 23.69635168014544 24.67596447656185 24.285226086207786 24.36977977951397 23.432149209045054 24.83158151723027 24.094670048899122 25.982790632746983 23.251238864616045 24.041525449530983 24.32495069593897 24.64893831020835 23.116772002701612 23.961533564631715 22.211103257119245 26.356970420383345 9.0 NA 4.0 1.0 16.0 32.0 15.0 46.0 14.0 22.0 15.0 15.0 12.0 28.0 12.0 35.0 14.0 19.0 20.0 25.0 20.0 20.0 15.0 33.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.7844745841342338 0.0031348505814530626 0.007931571851295751 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity molecular_function 23.937653651451463 21.750078807263183 22.86368165588077 16.137602048274925 23.79974701423856 22.44327910515069 24.052918559483523 21.02077624806545 21.203049503895343 20.992499398593953 23.60517874145875 22.503048870963944 24.12131768566041 19.155231572897 22.10657054250258 21.79842299889952 21.970449315095767 18.714861436725574 26.153184253359104 22.919589442663817 23.993382535842514 17.024143842810304 22.836420378612036 23.08118551383286 23.553011873746296 22.19162882572607 8.0 1.0 6.0 6.0 20.0 8.0 10.0 4.0 12.0 14.0 12.0 2.0 7.0 9.0 6.0 2.0 34.0 16.0 12.0 1.0 11.0 8.0 11.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.18757484418828 0.00268017172806849 0.006910856026093958 GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity molecular_function 23.99323055486009 20.551739796788773 20.830278972846312 17.04802299911574 NA 19.434693053046544 23.448676761342696 19.18582488525445 21.6210880637988 20.45987994684464 23.63597234176449 22.543325616568108 25.627076536954018 17.759900062132274 25.68015632695702 NA 22.13135786201301 19.376512177150346 22.514637214130374 NA 23.59255635442197 NA 23.53455156519068 20.354924880642393 23.647183754834032 21.30711681697357 4.0 1.0 NA 3.0 4.0 5.0 4.0 4.0 7.0 7.0 6.0 1.0 3.0 NA 3.0 2.0 6.0 NA 6.0 NA 6.0 1.0 5.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.4414907580713177 0.0007226712449063695 0.0024777299825361238 GO:0004743 pyruvate kinase activity molecular_function 23.153795233120128 23.906052275422173 17.64983393362734 21.395548620126874 19.670958700056502 21.328886303618397 21.13627222183549 25.05946197786552 21.66805494137597 23.915152421024146 23.07009262460131 23.709870111752164 22.914407498007414 24.12145346342425 22.899260996279306 23.422050136438244 22.83763925999166 23.650599788189588 25.56881442962174 23.443172172359468 23.894157567010197 21.11687981936751 22.214656279074305 25.669511302798142 21.540552160504255 23.105932120058338 3.0 1.0 2.0 2.0 4.0 3.0 4.0 6.0 5.0 6.0 6.0 2.0 5.0 2.0 4.0 4.0 16.0 10.0 4.0 2.0 5.0 2.0 4.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7522570423020447 0.0734883472918226 0.11239394291690516 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor molecular_function 22.98069357109241 24.384870855649915 22.593695666328593 23.875840742043405 22.52379822836101 24.590653343002273 21.770205578509866 24.6729098504478 21.806200748409317 24.32073554399039 23.49539496453197 24.183755414792962 23.74981264264241 23.72413100807826 21.590673982759824 24.34497339892242 22.647047603141694 24.54105706044093 22.696212352799314 24.560826425629678 23.77876595388718 24.171376836992522 23.844417146830743 25.00957557095817 22.897565977885762 24.13838800116945 14.0 15.0 13.0 23.0 14.0 24.0 13.0 25.0 26.0 31.0 20.0 17.0 13.0 19.0 15.0 26.0 19.0 28.0 26.0 18.0 22.0 28.0 21.0 20.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.4041772845575053 6.784570247173055e-05 0.0005498145239267514 GO:0004765 shikimate kinase activity molecular_function 20.20124941288012 20.664358947636927 17.154141312292992 NA NA NA 19.854482689850308 21.613303900987557 17.827325243433744 21.726855605163454 19.60168023254128 21.493359119370524 20.709775178157564 18.485874906716198 19.049886390772134 17.714356313182652 20.305814247875677 20.583208467421716 21.72740162944253 20.37153535912482 19.47241724117927 17.614425750128852 20.969706212778007 16.45404270240833 20.345072855410148 21.60385012413279 1.0 NA NA NA 4.0 6.0 2.0 9.0 2.0 11.0 8.0 5.0 2.0 1.0 4.0 6.0 11.0 6.0 3.0 2.0 10.0 2.0 5.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.46310953475680705 0.72477122130619 0.7743276961229171 GO:0004775 succinate-CoA ligase (ADP-forming) activity molecular_function 23.140423808038612 21.024932226183893 18.564558393349085 NA 24.6714792461206 24.025584977657875 20.625898456917888 19.486639439662472 21.508436503136405 NA 22.891705635114626 18.620784676902627 21.59480509657629 16.54746113620611 20.2525058398697 20.023132838477878 18.848773254747968 18.91423083289784 24.68060310733821 15.866468028083654 23.7460026645818 18.378956927769046 24.511307224654328 19.595958159997817 20.697517381329238 18.061467457247268 3.0 NA 24.0 20.0 5.0 5.0 13.0 NA 16.0 2.0 14.0 2.0 4.0 1.0 2.0 4.0 41.0 1.0 25.0 2.0 26.0 6.0 8.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.1154915818547195 0.005615998772030996 0.012720084333021204 GO:0004794 L-threonine ammonia-lyase activity molecular_function 23.799092534724625 21.71859960238447 23.185262694957533 20.59446847769782 NA 19.328251166193105 22.38081787802773 20.39505756871264 22.26927905954475 22.013052666533696 24.358572268902197 23.943404148600226 24.047749154508885 21.55296112213189 22.66231455221388 20.948775011634353 21.071895711687226 18.616361633356306 26.049130127847853 22.641813481365126 23.088158361962357 20.158113911537093 23.277477093557817 21.21598785097968 22.032780570611454 20.759467481647025 3.0 4.0 NA 1.0 9.0 4.0 8.0 6.0 16.0 9.0 9.0 8.0 8.0 3.0 4.0 2.0 12.0 12.0 6.0 4.0 8.0 7.0 9.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.0804929323401566 0.0016962207449685985 0.0049575725754585735 GO:0004802 transketolase activity molecular_function 24.91056824701624 23.893948146394038 22.96306694505341 23.367111101755114 23.45040053531819 23.353391263977837 24.716217036498772 22.4811732137632 24.92992393788672 23.08237206218483 25.6353282080674 24.47915281336072 25.43289460109573 24.621944975758552 24.204527634389034 23.77353338410932 24.2003759970504 23.41827105076529 24.97508521246872 24.079432604655644 25.47989653309793 23.3431912118082 25.38790793981525 25.214660810209107 25.23818242863597 23.056609178634723 11.0 9.0 11.0 16.0 19.0 14.0 25.0 10.0 27.0 19.0 21.0 8.0 23.0 13.0 19.0 12.0 18.0 23.0 25.0 12.0 25.0 15.0 26.0 15.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0166201006222018 0.006656727227605034 0.01478219854101616 GO:0004807 triose-phosphate isomerase activity molecular_function 23.84867828737607 21.874774162425197 23.169677537281064 19.05941279865511 23.75077603416505 20.966030159558347 23.793317379281632 20.801594324605254 23.22290605397645 NA 23.00716222436689 22.05211387323773 23.13703456899301 19.553105401680227 23.85569116926548 20.02639863227804 23.426585247024803 20.669211381659178 25.241517558152466 22.71666289380785 24.29396693970089 20.061990957804912 23.541519287140915 23.91489840156857 24.005621665179444 22.56901326985455 7.0 1.0 7.0 2.0 6.0 8.0 3.0 NA 5.0 8.0 7.0 2.0 10.0 4.0 7.0 3.0 10.0 8.0 10.0 3.0 6.0 4.0 7.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.9739041249508738 0.00045130665609211163 0.0017224180636176002 GO:0004812 aminoacyl-tRNA ligase activity molecular_function 28.139474151607104 27.809486527337622 26.399716267990595 27.06823088877112 26.48231936891595 27.885548924043665 28.05376794281832 27.601340090479212 28.973621372408573 27.4806008999867 28.789009547672748 27.862764805439035 28.479990138883576 27.627306178142586 28.341466614990978 28.116739967546746 27.855443038070348 27.71664569454989 28.331876664821536 28.239406678447622 27.12710021105267 27.608971829275237 28.239178699964427 28.20309942340321 28.33102433706509 27.89457400624983 149.0 137.0 141.0 186.0 366.0 258.0 490.0 295.0 479.0 276.0 458.0 203.0 427.0 243.0 317.0 261.0 582.0 411.0 223.0 216.0 472.0 231.0 414.0 304.0 21.0 17.0 19.0 19.0 21.0 21.0 21.0 20.0 21.0 20.0 21.0 20.0 21.0 19.0 21.0 20.0 21.0 21.0 21.0 21.0 21.0 21.0 21.0 21.0 0.32998762426948147 0.11903289845700783 0.16804644488048165 GO:0004813 alanine-tRNA ligase activity molecular_function 23.974360803660588 24.75896155305695 24.409632989316826 24.62109447807106 23.57326857424989 25.56140091289537 23.63414719239693 24.08450888767695 24.2682446513649 23.74627585002871 24.49639150628332 25.17818240553823 24.149702235773873 25.122386899673423 23.537828176379122 24.656672598281197 23.489910875417127 23.619414925005774 24.50784709673655 25.10807971230539 22.839979789407767 24.90915422705124 23.265845488031587 25.121384509250003 24.397564231606523 23.88772324704365 17.0 13.0 7.0 16.0 18.0 16.0 27.0 15.0 29.0 14.0 24.0 13.0 17.0 15.0 20.0 16.0 34.0 27.0 10.0 15.0 16.0 15.0 27.0 17.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7846007493963612 0.006656727227605034 0.01478219854101616 GO:0004814 arginine-tRNA ligase activity molecular_function 24.53209709328184 24.06354033344304 22.763408448630877 23.04075979531702 22.681673317227396 24.235130860656852 24.525956638020137 23.40549361584677 25.68595500982861 23.38669368625925 25.228565951890545 24.228383203851706 24.712931636653646 23.327531161352766 24.09077214862786 24.366872556397468 23.64507779236681 24.734757714363926 24.40966404120559 24.610204419427642 24.48318129007962 23.800516755715904 24.64543706903968 23.374472129140248 24.807210917833 24.794827352278126 18.0 15.0 18.0 19.0 50.0 25.0 56.0 37.0 56.0 33.0 54.0 18.0 47.0 25.0 28.0 25.0 54.0 31.0 33.0 28.0 50.0 19.0 48.0 48.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.4685567598388012 0.2040238704744366 0.2705863871967023 GO:0004815 aspartate-tRNA ligase activity molecular_function 24.45700257345189 24.66391742120676 22.958459991346512 23.866043231671235 23.011453590496906 24.19153818826128 23.830585283103872 25.09238555603407 24.89533397257225 24.55366898135652 24.97894040573162 24.458040479995407 25.186914617581703 24.760957957230488 24.12628786485979 24.70883908826971 24.540380833057466 24.290913475050612 24.50553519760407 25.222899888521233 24.695065094024425 24.65705447961527 24.443785692180608 24.808296853186153 24.623792054633714 24.82440987967452 16.0 16.0 17.0 27.0 24.0 33.0 41.0 35.0 35.0 29.0 40.0 30.0 36.0 29.0 29.0 27.0 42.0 44.0 27.0 30.0 38.0 30.0 35.0 29.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.20691484775487012 0.29869755599497017 0.3712893923124729 GO:0004816 asparagine-tRNA ligase activity molecular_function 24.278854716681266 22.468416532045325 21.175832198742665 21.1751756750915 22.29042039464266 22.85096596388281 24.45683941269625 22.423297379911613 25.159484868604427 22.040751649389247 24.83718151464008 22.930316755925087 24.32897267805463 20.979585844313828 24.570904637402958 22.98327952667076 24.18375030148173 22.365080651807066 24.444280502784142 23.579827274732214 23.014397812628555 22.119038849847172 24.667773115977262 22.34560795260461 24.472264798473606 21.774953744179243 6.0 2.0 4.0 3.0 24.0 3.0 28.0 4.0 27.0 9.0 25.0 2.0 30.0 6.0 21.0 6.0 26.0 21.0 9.0 4.0 27.0 5.0 26.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.8104381846359416 0.0018227351663913985 0.005134928866041682 GO:0004818 glutamate-tRNA ligase activity molecular_function 23.919467812966147 23.66563995302188 22.208091659250393 22.81954641500793 23.340910178066544 23.199388190434927 23.71871174716083 23.111763262492172 24.937065177272874 23.173293151480856 24.3513400978868 23.987161340117154 24.583326278733665 23.69514866326389 23.984268175909854 24.202661527578144 23.404984679011324 23.77912709382976 23.796345740814672 23.526016262037 22.809360431047697 23.852661005356087 23.86776321776021 24.30456058434068 24.063285094607053 23.547471960317463 9.0 4.0 10.0 7.0 17.0 15.0 30.0 16.0 29.0 18.0 27.0 11.0 27.0 15.0 19.0 15.0 30.0 23.0 15.0 14.0 29.0 13.0 25.0 19.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.25382785994426627 0.3864762307712327 0.4687291895068012 GO:0004819 glutamine-tRNA ligase activity molecular_function 20.78874002112407 20.500419752353142 18.666247761473237 NA NA NA 19.95121959171539 13.595834209388432 18.104277619309983 21.364217915766076 21.34787144167828 21.342061787420885 20.79093555182931 20.623187579595076 19.836763964489613 NA 19.121772049965557 NA 22.517438227051915 20.749314251632175 20.647231773333658 16.236168152934756 21.70786195701716 18.840267589323197 20.137248263347235 21.29467211924024 2.0 NA NA NA 5.0 1.0 2.0 10.0 4.0 5.0 3.0 3.0 4.0 NA 4.0 NA 15.0 5.0 3.0 1.0 5.0 2.0 4.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.28832026877092787 0.7411815058736042 0.7865599654168861 GO:0004820 glycine-tRNA ligase activity molecular_function 24.288048627755746 22.023577948224936 18.62265544615126 18.749307786218367 17.70078458460587 19.936111341931127 24.31635871289061 20.18769278800088 25.882771205028742 19.85984897845375 25.28776902029002 21.380842784379155 23.839261717432446 20.587838084390032 24.39932745992513 22.51071279616217 23.532921242601805 21.50663675054802 24.23116274929191 24.314555487335898 23.14404668705063 20.132581622838188 24.103924082534828 23.467299957901268 24.587577058345666 19.41244170911771 2.0 1.0 1.0 4.0 27.0 2.0 41.0 2.0 34.0 4.0 26.0 2.0 31.0 3.0 13.0 2.0 43.0 21.0 5.0 3.0 33.0 6.0 26.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.2644706795308096 0.01531382171343201 0.02967647437634029 GO:0004821 histidine-tRNA ligase activity molecular_function 23.284413451235316 22.520761944851213 21.31142336881207 20.722101135678905 23.03785261695022 21.73971540016738 23.2638932221811 19.576934768528865 23.074935851948656 21.43101432108108 23.367201563687235 22.55314977703139 24.121843638816102 23.553790724938736 24.081337644797248 23.8925707599555 22.97411749382656 21.581265144659234 23.065324822685625 23.498766834365266 23.326702560935416 22.82223721351389 23.344348131346113 22.124622560930238 22.831517833328036 21.163760550901454 2.0 2.0 7.0 4.0 9.0 2.0 8.0 6.0 11.0 9.0 13.0 4.0 10.0 6.0 8.0 7.0 16.0 9.0 9.0 4.0 12.0 6.0 9.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.7636515063841038 0.03766692222862868 0.06276144050911694 GO:0004822 isoleucine-tRNA ligase activity molecular_function 24.74034884630905 25.266791425815292 21.914816646601118 25.01705868273325 23.87640746193883 26.05916348655526 24.611073566419613 25.09494625822121 25.800297490661173 24.593712963218035 25.26865063771277 24.42931731546367 24.90809802818913 25.29703411836475 25.43260002752746 25.63638960843965 24.016560155958786 24.12020266971283 24.34067076920772 25.268766760202197 22.682755868216315 25.299963831815518 25.215866419581708 26.22102506641136 24.922825171516944 24.58983430908473 11.0 26.0 19.0 41.0 29.0 40.0 36.0 39.0 29.0 26.0 31.0 22.0 37.0 36.0 18.0 43.0 45.0 38.0 16.0 30.0 47.0 29.0 29.0 41.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5264425795062415 0.10596880912720232 0.15148805703407617 GO:0004823 leucine-tRNA ligase activity molecular_function 22.791842634745173 22.363846189347104 19.923243027306608 21.61528680728048 20.349355653020712 21.589902561631323 22.508916830853053 21.90267618224609 23.495850565661517 22.041728449019065 23.90459169019726 22.87717415549545 22.90935706513154 22.035336657123384 22.19677389194871 22.76391758417513 21.979682605144838 21.85884527112279 23.514883239599943 22.143906655631145 22.0385798866587 22.686705973245143 22.860404106945968 23.05756237031566 23.33444797085497 22.763191960097018 3.0 3.0 4.0 4.0 12.0 6.0 20.0 2.0 21.0 5.0 12.0 5.0 10.0 6.0 11.0 3.0 23.0 6.0 7.0 3.0 15.0 6.0 18.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.4279964453980689 0.24821307898992373 0.31935043564889154 GO:0004824 lysine-tRNA ligase activity molecular_function 25.11820339173644 24.799133688883906 23.35950283933311 23.121794773068515 23.200702187617626 24.07643606287117 24.89874043218268 25.175645194472562 25.72244923297973 25.195174136202308 25.846901775868968 24.646673358068853 25.45537661742404 23.704723771748448 25.471227469943447 24.94356535649184 25.55446466119853 25.54432411757757 25.348249753298017 24.813572357402762 23.832105397201147 24.45696685381093 25.096408014453587 24.54715862681168 25.03202722111731 25.54681703319166 17.0 12.0 15.0 18.0 31.0 34.0 38.0 28.0 41.0 27.0 39.0 22.0 43.0 32.0 34.0 30.0 42.0 34.0 27.0 28.0 40.0 19.0 31.0 28.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.3190697028525342 0.2253456937016668 0.2954111614912607 GO:0004825 methionine-tRNA ligase activity molecular_function 22.88185684370804 22.33713494001575 21.65131712282637 21.845415864087435 21.515000781078843 19.47174413289898 22.28547773442254 22.16064769565299 23.348675056135484 22.677611327235713 23.610760278422237 22.837349441503072 23.90113942917457 22.489404045504603 23.336604579535003 20.21309729262543 22.720329360033286 21.309732083963734 22.79392935837688 23.56095642536376 20.313361826177747 20.3978755113905 22.345577769913945 21.271599068484388 23.361838187561307 23.759713166377807 4.0 4.0 6.0 3.0 10.0 9.0 15.0 15.0 15.0 14.0 22.0 11.0 14.0 5.0 10.0 8.0 19.0 16.0 6.0 7.0 15.0 10.0 16.0 21.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.5447219036922881 0.14891467317876572 0.20512749682902828 GO:0004826 phenylalanine-tRNA ligase activity molecular_function 23.81812914956636 23.4545385131128 21.647135186692825 23.282735149940525 20.662371372747806 22.19270141280311 24.2634892615598 23.102258570204228 24.8029093622448 22.9208858618067 24.158080667315435 23.98999291599677 24.25348696406148 22.16686572100749 23.845387522928252 23.90056796854494 23.471537141175343 23.115989329134425 24.40318318954115 24.44295461637254 21.659369225228186 22.736807434454136 23.634433738676357 24.47125329108284 24.193426313172523 22.702124733573235 7.0 8.0 4.0 7.0 22.0 14.0 22.0 19.0 24.0 16.0 27.0 10.0 19.0 11.0 18.0 11.0 37.0 34.0 11.0 12.0 22.0 18.0 20.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.3635906364535586 0.4189234409463829 0.5022252202700153 GO:0004827 proline-tRNA ligase activity molecular_function 22.81122050188932 22.263445084717755 22.014736933599554 21.662319445360946 21.64216632734921 23.38972987329009 22.189809945015426 21.68999116481156 23.592337485934852 22.126781595830174 23.436637384426252 23.07969670775617 23.134321350210648 22.39742325526037 22.444142286020867 22.094027414476155 21.991521931843838 21.38923644349377 23.929940880311538 22.40020391608828 19.122241528080302 21.56265348525627 22.965541757114625 20.15663579216436 22.96629442858009 22.681855009785515 9.0 3.0 6.0 7.0 13.0 7.0 18.0 11.0 14.0 11.0 15.0 5.0 12.0 4.0 11.0 9.0 26.0 18.0 5.0 7.0 20.0 4.0 14.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.5477754171715645 0.16585666034291002 0.2267131567447445 GO:0004828 serine-tRNA ligase activity molecular_function 24.353513870958857 23.651786996489342 21.92688504975872 22.09363262994563 20.103673481662334 23.95360814557907 24.549738103221593 22.9785147685096 25.46929330005225 22.277190632412683 25.349558330860233 24.04902725358488 24.357617560745076 22.4169120456153 24.288762329884428 24.156755339355698 23.62755270230474 24.53058568410441 24.53857842044181 23.71146892065769 22.517907161322913 22.89235140343929 24.751433002439192 24.620481274048103 24.562527842501307 23.37449570345817 6.0 7.0 4.0 8.0 16.0 9.0 32.0 12.0 25.0 17.0 13.0 7.0 22.0 12.0 15.0 14.0 20.0 20.0 9.0 8.0 24.0 14.0 15.0 17.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.7017268744695144 0.13332693177434943 0.18549833985996442 GO:0004829 threonine-tRNA ligase activity molecular_function 23.53538311903129 22.12650354016345 19.19914559738916 NA 19.467372072185334 17.706289664186748 22.96417370046905 20.99902030504919 24.426934861275658 21.705910567380425 23.787687160497303 19.86627962689327 23.57136375288651 21.545084273027754 24.54212165514152 23.414788423360033 23.832383915692574 22.687081473501483 23.96147112099688 22.757843102345234 21.40630494059528 21.323936915991602 23.942562342831412 21.955009917680716 23.549819130519253 23.08547781344493 3.0 NA 2.0 1.0 9.0 3.0 14.0 3.0 13.0 5.0 18.0 3.0 21.0 6.0 13.0 3.0 24.0 16.0 8.0 4.0 22.0 3.0 12.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.4088795788678397 0.022774727854040278 0.04131229703756143 GO:0004830 tryptophan-tRNA ligase activity molecular_function 21.483835471435896 21.28531610193625 19.166298707702246 20.611814537137533 NA NA 20.724393887808887 21.153110979255267 21.259882088464924 21.72273313391219 22.069702909863313 21.574771347858285 23.034673594916896 21.191903404142508 20.68033245781926 20.96623273602314 20.78521633408784 21.300248365826832 22.090047423802186 21.15690000056982 20.979540832721824 19.486993441596198 21.315592291584004 22.57948433471905 20.78326672915211 20.22714127948785 3.0 5.0 NA NA 5.0 10.0 9.0 10.0 8.0 8.0 9.0 8.0 5.0 4.0 5.0 9.0 9.0 7.0 5.0 3.0 5.0 5.0 5.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.1985193694996461 0.9215372441867455 0.9380738015865078 GO:0004832 valine-tRNA ligase activity molecular_function 23.64879279302003 23.36547237566851 22.464534595388322 23.05208446633339 21.600222459921586 23.655196732056552 24.351303250544014 23.044793763510484 23.94854184005379 23.29716875892757 23.92863815692139 23.29147697050525 24.054793167081694 23.05308041649529 23.739969579398426 23.818535486369424 23.544304465859383 23.21835580697373 23.78108842660743 23.528734493205803 20.84035713445889 22.784837880739783 23.924846562626534 23.285280186867066 24.21033993302461 23.90814437515904 7.0 14.0 10.0 12.0 27.0 18.0 26.0 19.0 27.0 15.0 34.0 16.0 21.0 14.0 25.0 19.0 37.0 27.0 7.0 8.0 24.0 16.0 32.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.28332041735151847 0.0940685547103812 0.1379524750629327 GO:0004845 uracil phosphoribosyltransferase activity molecular_function 24.341389922586806 24.564845653453574 24.02777670212247 23.70696956465752 22.335062750130927 23.810097119633078 24.14654772814273 24.058571645435723 24.465279374020014 24.187885174123807 25.203104536647498 25.331318390177174 24.847447000872684 25.178343151493607 23.204149601870398 23.58313585316506 24.36996903654771 24.276367121193857 24.16131230083109 24.587717058357267 24.734038721898013 24.17680338168838 24.263705722848787 25.80601248716413 24.515288341892727 24.011067528764194 10.0 10.0 4.0 10.0 17.0 19.0 24.0 21.0 20.0 22.0 24.0 15.0 20.0 15.0 20.0 20.0 23.0 24.0 16.0 9.0 21.0 23.0 22.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.2234557308667675 0.9539596927720386 0.9577970205788449 GO:0004849 uridine kinase activity molecular_function 20.520541915828684 20.4908352228905 22.0883017682046 20.035727228961804 22.057624423516394 21.269796998499924 18.170389447554122 19.927545018479787 16.375003804514847 18.388374377896575 18.386000946322447 20.70242105740529 19.33222723704318 20.50978290154092 20.278315925299214 20.94182055378099 NA 19.60496790857906 19.7538779863368 20.234694702779038 21.619019742908392 20.05315743805814 19.351285269795152 21.689092348606334 18.16322906980897 19.966843583917235 3.0 1.0 3.0 4.0 2.0 1.0 1.0 1.0 2.0 3.0 3.0 1.0 1.0 3.0 NA 3.0 3.0 1.0 4.0 1.0 2.0 5.0 1.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.029706692938184176 0.21835469056590173 0.2883668294457623 GO:0004851 uroporphyrin-III C-methyltransferase activity molecular_function 22.91219796381031 21.227040281165337 17.856981015095318 NA 24.326144783110948 18.871532802235123 22.859171754863052 20.52409874719955 21.00143308482556 22.69508809959413 22.972001530653163 22.24681707347944 24.18033609895739 20.240849470180237 17.21620562138326 19.17056428130296 21.50347597238595 20.674164639726808 21.301835426827296 21.17613040867666 23.44713245366036 19.282826263703576 22.939178730088358 20.009505290888754 23.431612732326485 22.437511960504327 2.0 NA 1.0 1.0 10.0 3.0 9.0 9.0 7.0 13.0 17.0 5.0 2.0 1.0 9.0 2.0 9.0 10.0 11.0 2.0 16.0 5.0 15.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.6851576826449737 0.036388866200708525 0.0618709877636025 GO:0004888 transmembrane signaling receptor activity molecular_function 21.892441252962414 23.322141965266013 19.262099925838925 23.66553146175148 21.580457805770525 22.15717207661529 22.123850588981686 23.00476205422985 20.93608203309884 22.247598380700712 22.62501622334616 23.14899606387205 23.44586247148552 23.753930365816398 19.434196492835245 24.291137657590603 20.34437384450316 22.737604912742878 19.236430534573763 22.82879585556263 21.790396644434857 21.511195266375523 22.496906778392443 24.547485913254718 22.58145187134979 23.025777737435583 3.0 15.0 3.0 8.0 7.0 14.0 5.0 14.0 8.0 13.0 7.0 17.0 4.0 13.0 4.0 14.0 4.0 13.0 2.0 9.0 5.0 19.0 8.0 16.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 1.0 3.0 1.0 2.0 1.0 2.0 1.0 3.0 1.0 2.0 -1.4297007123035996 0.00268017172806849 0.006910856026093958 GO:0004970 ionotropic glutamate receptor activity molecular_function 21.73208382752203 22.831843971492724 18.79217006619826 23.60576789982731 18.96913902434685 21.385583837823475 22.123850588981686 22.63453745770861 20.74790084914752 22.020697380576426 22.55498842631577 22.349891181753698 23.318880281897147 23.499019251225857 18.950346776166604 23.098095820898795 20.34437384450316 22.018259824941783 17.728898713716852 22.530808747657428 21.790396644434857 21.229408086805595 22.496906778392443 23.971760247964745 22.58145187134979 22.91688959186273 2.0 14.0 2.0 7.0 7.0 11.0 4.0 11.0 7.0 11.0 6.0 12.0 3.0 11.0 4.0 10.0 2.0 10.0 2.0 8.0 5.0 14.0 8.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0997601439706948 0.02092133533779403 0.038284203081476474 GO:0005198 structural molecule activity molecular_function 30.826810357528394 30.04166464119346 29.879060037556965 29.330719628898184 29.61828554557143 30.03047674301384 30.252766688906732 29.905865814464825 30.90952691489171 29.491857102752448 31.01525152080452 30.415113595022344 31.01531175593 30.044213283924922 31.19087317747219 30.31272593323561 30.41631253092598 29.795738971097737 31.61940681789997 30.432201739070482 30.730915258507967 29.890222993704963 31.3201420022674 30.33911472140676 30.712797770964205 30.06476683188514 411.0 148.0 232.0 394.0 411.0 282.0 638.0 254.0 611.0 397.0 521.0 219.0 776.0 276.0 466.0 252.0 666.0 530.0 473.0 154.0 576.0 213.0 433.0 304.0 4.0 2.0 4.0 4.0 1.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 4.0 2.0 3.0 3.0 2.0 1.0 0.7851457163349345 0.005583616806378765 0.012692811975156102 GO:0005200 structural constituent of cytoskeleton molecular_function 20.822452504105442 20.0614659439034 19.151519743716268 19.65686904590007 21.998153869755892 20.90710279719563 NA 19.940603404863968 19.27125512533839 NA 22.66373899163034 19.62429781255448 20.61034575963044 20.30371049874706 19.726208762053695 20.64308412774261 21.01400486748545 18.963166185639288 19.014510884390265 19.60781951431197 18.00603587084595 NA 21.41360493522225 19.92960630029664 17.43245593157638 NA 2.0 3.0 3.0 3.0 NA 3.0 3.0 NA 6.0 3.0 3.0 2.0 2.0 5.0 4.0 3.0 2.0 2.0 1.0 NA 3.0 2.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.760986560202042 0.9696981596093224 0.9728161601225356 GO:0005215 transporter activity molecular_function 31.19129329834149 32.12754425608194 31.01543797620516 31.56667019642407 30.75813060064733 31.83990444297281 30.784340006101484 32.113440546444394 30.993336964158352 32.036948219795214 31.36776827986051 32.21064149142199 31.36514523268804 31.95824341327188 31.094885691213108 32.520809480465886 30.99323188344279 32.274363644692286 31.629509072248673 32.16289524878715 31.584010047976466 31.86914565731956 31.124033168467705 32.456322442215125 31.276196065813746 32.2487434381564 1829.0 2220.0 1672.0 2531.0 1659.0 2976.0 2185.0 2924.0 2122.0 3029.0 2358.0 2551.0 2328.0 3375.0 1773.0 2785.0 2188.0 3107.0 2035.0 2762.0 2039.0 2998.0 2226.0 3320.0 4.0 2.0 3.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 -0.9362509577404516 5.312128159411724e-05 0.0005099643033035255 GO:0005342 organic acid transmembrane transporter activity molecular_function 23.57131237640079 26.63616601039716 23.018965244291124 26.16633989585484 22.175423888906625 25.512184659178 23.01580583901021 26.681645037924053 23.57133692642639 26.28074583493534 24.83579232072389 27.006223641812028 24.468005623455035 27.24852326638691 24.143262977887105 27.003463251640248 23.04374436245043 26.61355449161952 22.899503230250488 26.2774226615906 22.0091938569585 25.40252335991735 22.94562178963097 27.70655036491237 23.8327921740344 25.910775892071616 32.0 132.0 23.0 112.0 21.0 192.0 28.0 133.0 41.0 159.0 62.0 151.0 49.0 224.0 35.0 166.0 16.0 139.0 13.0 149.0 31.0 214.0 36.0 129.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 4.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 -3.0648536339963712 3.225641456243767e-05 0.0005099643033035255 GO:0005351 carbohydrate:proton symporter activity molecular_function 20.501036593480706 23.728706852133993 22.100380247797798 22.674448632162303 21.96373226270362 24.43681471360301 NA 23.457347784897145 NA 23.574173848616372 NA 23.63717445346889 20.09761022500427 23.204005773650326 19.667536539851948 24.58429312882122 16.278678352834515 23.15904661410544 16.796448851792558 23.71599810822632 20.126252838762888 22.54418046217545 18.250283126652374 24.07663721192677 20.15158040755004 24.1477099618221 9.0 10.0 11.0 17.0 NA 21.0 NA 20.0 NA 14.0 4.0 14.0 5.0 35.0 1.0 18.0 1.0 13.0 4.0 17.0 2.0 24.0 3.0 24.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.227670258653287 0.00012423612343122087 0.0007006959432226783 GO:0005354 galactose transmembrane transporter activity molecular_function 23.66933425816081 20.882607206535283 20.989802794646238 NA 21.23997658348418 NA 24.305001485414838 19.25932257296694 24.224389754316558 18.250229574480837 24.645676897079444 21.31057151629368 24.106766761711878 NA 23.79636005854949 21.221192011333546 23.55078160800669 NA 23.20811447676383 21.5825925107308 23.362326320249363 17.459009620235655 23.359267642721864 22.188423952827 23.609344514732264 20.397323739388217 4.0 NA 4.0 NA 27.0 2.0 27.0 2.0 29.0 9.0 25.0 NA 19.0 3.0 20.0 NA 24.0 8.0 19.0 1.0 30.0 4.0 24.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.786727051625526 0.001560350789113223 0.004603588143766672 GO:0005488 binding molecular_function 35.90232433845293 35.83061695461789 35.383445238353474 35.156864495360864 35.318864201155435 35.8558901850496 35.66338131938589 35.92990385314322 35.98032597000682 35.826874859533184 36.10529744779989 35.91904910296082 35.97222304912137 35.528834257868894 36.066089239512216 35.93471210172646 35.550374807775405 35.796854373923594 36.45620591114113 36.05905970462333 36.061949956000454 35.89239390141067 35.9794121011765 35.839295304708834 35.88410092243981 36.018756622990715 18837.0 17553.0 16585.0 23352.0 25821.0 28424.0 31044.0 27244.0 31543.0 28104.0 30428.0 22361.0 33141.0 27617.0 24245.0 27867.0 39484.0 34571.0 23295.0 22409.0 29752.0 26765.0 29680.0 28591.0 16.0 16.0 16.0 16.0 17.0 16.0 16.0 16.0 17.0 16.0 16.0 16.0 16.0 16.0 17.0 17.0 16.0 16.0 15.0 15.0 15.0 16.0 16.0 16.0 0.07170738383504016 0.29869755599497017 0.3712893923124729 GO:0005509 calcium ion binding molecular_function 23.902537562577248 22.62514827006916 26.424456350025054 20.09216517063561 17.555919751985176 NA 23.299156193148857 22.148174156639442 21.80789571617301 18.43061677358713 22.61264925782791 25.23140067103402 23.449101616855216 19.996055102134854 24.325176596496835 21.952734888097787 21.73861297666883 18.678971959192427 21.342820444388565 20.17589340307865 23.279964369441434 23.363064932111 22.16818731543611 20.911761066704727 24.51554809101449 22.558916190158754 24.0 6.0 3.0 NA 14.0 4.0 7.0 2.0 13.0 29.0 11.0 8.0 15.0 6.0 11.0 3.0 5.0 4.0 8.0 4.0 5.0 9.0 9.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.2773892925080865 0.08483774479657043 0.12710384814660253 GO:0005515 protein binding molecular_function 29.20155158135513 30.43760881888664 28.909754946713754 29.668910894639147 28.20977418951541 29.8599182411825 29.03790327928484 30.63164439206793 28.53540366814249 30.74977789812662 29.116598183491522 30.43370035239811 29.35525569553792 30.17263316753385 29.07271267369807 30.544392904947664 28.921334000964432 30.40313797270568 30.6536064580577 30.92655265269877 28.86211461180284 30.21287583829281 28.93874892861613 30.253964077051428 29.20766111670683 30.854574724810305 214.0 142.0 169.0 260.0 231.0 249.0 273.0 277.0 276.0 271.0 274.0 213.0 306.0 260.0 238.0 276.0 364.0 338.0 248.0 254.0 278.0 261.0 261.0 313.0 9.0 8.0 7.0 8.0 11.0 8.0 8.0 8.0 12.0 8.0 11.0 9.0 10.0 8.0 9.0 11.0 9.0 8.0 8.0 8.0 9.0 8.0 10.0 8.0 -1.2360572375315115 0.0002755038114342687 0.0011655212090507369 GO:0005524 ATP binding molecular_function 30.026233179612323 30.439629604444853 29.45279685434732 29.950460166295013 29.55856423367574 30.51316805433061 29.839372061238237 30.69664908932692 30.184077260860995 30.2885250466081 30.476475680561713 30.47439860752167 30.196871499361038 30.23792390471748 30.108112015296804 30.644859497106747 29.715723206101146 30.45827655913568 30.59861415066485 30.676351570032754 29.69639831868217 30.29734934115888 29.834197114089985 30.484514244837953 30.158703280514807 30.386599585462665 595.0 718.0 620.0 904.0 941.0 1104.0 1112.0 1005.0 1158.0 1021.0 1156.0 888.0 1153.0 1062.0 848.0 1066.0 1483.0 1295.0 748.0 841.0 1056.0 1048.0 1081.0 1050.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4133964248325306 0.00268017172806849 0.006910856026093958 GO:0005525 GTP binding molecular_function 30.09283771973838 29.05896123803901 29.14402280576984 27.811071290533057 28.880096712916174 29.32632017120475 29.798740521958862 28.79086315865789 30.26239377818592 29.158719469683625 30.284846992140352 29.363862374038554 30.164702383675014 28.596515014410485 30.125604828689074 28.700450667160982 29.56631981539227 28.7243913075442 30.703904035376397 29.292144362145372 30.64529090999373 29.56345946560789 30.39875727472937 29.053936852539266 30.048000557737225 29.490497782560226 181.0 105.0 106.0 157.0 210.0 187.0 273.0 203.0 245.0 206.0 206.0 125.0 288.0 174.0 205.0 184.0 295.0 270.0 206.0 153.0 250.0 165.0 235.0 201.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0338764816993695 0.0006583371695572323 0.0022696264851033866 GO:0005575 cellular_component cellular_component 34.353807296626336 34.51896516774268 34.14075603080311 33.9885195034381 34.08673960694232 34.45700232866195 33.99263526991929 34.51876202172823 34.39907539392107 34.438746744663355 34.469902416095316 34.642392498041694 34.48916705701386 34.39900662374497 34.65787369366089 34.697593362893016 33.90632117530974 34.569445039368034 34.62899068272721 34.69166170124386 34.388867761464205 34.41472450009541 34.57946941947132 34.73915826527649 34.267163832840254 34.52562682014707 7638.0 6509.0 6586.0 8967.0 7934.0 9773.0 9614.0 9434.0 9844.0 10108.0 10016.0 7705.0 11016.0 10203.0 7677.0 10042.0 11544.0 11364.0 8968.0 8004.0 9709.0 9706.0 9611.0 10364.0 12.0 12.0 12.0 12.0 12.0 12.0 14.0 12.0 12.0 12.0 14.0 12.0 13.0 12.0 12.0 12.0 12.0 12.0 11.0 12.0 12.0 12.0 12.0 11.0 -0.1651578711163424 0.0832645166635504 0.12534875367444018 GO:0005576 extracellular region cellular_component 29.272702685182853 30.396692694675625 29.87055149101369 29.69678044403717 30.27941668997428 30.447867433444614 28.77285635424139 30.05879004846256 28.34685611642881 30.41963793446444 29.266069684677426 30.3918859337718 29.051622370012232 29.77257516983601 29.631082772133666 30.616243015142945 28.77461462169583 31.14236914590881 29.075158469455115 30.56368671313617 29.41274553125934 30.34292147009285 28.219992078012663 30.395412964311102 29.189958690208307 30.35154991730677 246.0 311.0 259.0 324.0 111.0 269.0 148.0 383.0 148.0 305.0 174.0 235.0 260.0 540.0 131.0 624.0 234.0 351.0 165.0 272.0 132.0 434.0 160.0 297.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.123990009492772 0.00010962068302139599 0.000648372570666835 GO:0005615 extracellular space cellular_component 22.667702364750532 23.15383025094169 22.8663913425894 23.242091398909484 18.377665523718203 20.03553157746874 22.86108648859168 23.17586810230551 22.129920047541308 23.425353132497314 23.94980903725284 24.21433870454516 23.03033967392982 23.489927523069948 19.77519378416396 21.77105497163681 23.22390653448127 23.52414506646257 23.18754746814625 24.017309089774447 17.883033456088405 18.36696111623289 18.74323614484179 22.647233215349946 23.745107787854295 23.176210463279162 6.0 13.0 2.0 5.0 4.0 13.0 5.0 10.0 10.0 15.0 6.0 11.0 4.0 14.0 8.0 20.0 8.0 15.0 2.0 3.0 2.0 12.0 7.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4861278861911593 0.2040238704744366 0.2705863871967023 GO:0005622 intracellular cellular_component 28.94375136459311 28.226875243388253 28.500765023792482 27.472637073237323 27.87434212504598 27.59947290151729 28.94538683399665 28.045486534858746 29.211454150998726 28.93901559966618 29.1994528118423 28.404395779327842 29.177798247308974 27.494042898801226 28.908280754234497 28.02886430758784 28.53572313580621 28.26943275113309 28.991480381025198 28.272895819811488 28.95915190256636 28.41818086259253 29.45917358880536 27.967357396681823 28.957619879483623 28.901143063649393 102.0 64.0 47.0 62.0 158.0 155.0 185.0 157.0 180.0 129.0 186.0 114.0 199.0 138.0 149.0 150.0 194.0 158.0 131.0 106.0 166.0 111.0 180.0 150.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.7168761212048551 0.0008121171348941295 0.002709952364566507 GO:0005623 cell cellular_component 27.33768789195191 27.90663761177353 26.5670876664286 28.24614493276876 27.167913285936947 27.81323632505575 27.69698328315343 28.47938425298344 27.094250613830532 27.826793321545786 27.40785474959149 26.88260936711936 27.96872226534295 28.28387633956109 27.229869603085252 27.977053245981512 26.669889479084052 27.64412049567645 28.06028986163283 28.386289666772146 26.998836396411853 27.63122889650785 27.268001646490717 27.67208706499555 27.099269727215425 27.2147267614681 71.0 75.0 59.0 101.0 87.0 137.0 83.0 104.0 91.0 104.0 91.0 87.0 103.0 109.0 78.0 116.0 109.0 129.0 73.0 85.0 97.0 119.0 87.0 98.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5689497198216209 0.01531382171343201 0.02967647437634029 GO:0005694 chromosome cellular_component 24.51567338779108 25.118310272525694 23.907197212254683 24.873411058987056 23.70456724252601 25.338845096771607 24.96782537586603 24.859478414377712 24.272591542177683 24.811969457271072 24.98854347575867 24.797022291709148 25.001999899847426 25.53290334760516 24.274087023307985 25.663103230010535 23.907826732714003 24.40721118455141 25.008058202583594 25.15351006627701 24.36520951936637 24.522055141594404 24.651384114780306 25.625804420195628 24.304866935975053 25.16907742331605 37.0 55.0 36.0 67.0 55.0 67.0 55.0 65.0 68.0 54.0 79.0 56.0 61.0 84.0 40.0 64.0 82.0 72.0 61.0 60.0 66.0 78.0 62.0 71.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6026368847346149 0.007911788680711459 0.016907384030013527 GO:0005737 cytoplasm cellular_component 32.216384988326425 32.37091900004493 32.26200090283773 31.812253271483563 32.157424995695465 32.38674585774144 31.849027086649627 32.43632397269121 32.07064726581668 32.353348591326736 32.241590462702014 32.514843511118286 32.20055097304021 32.084166635866474 32.334767900785515 32.49930314814111 31.6033886422194 32.375238219028034 32.7907855631509 32.537171685304024 32.546166637425216 32.38755831300394 32.130588219909896 32.45582099559558 32.055687720727136 32.45592323958924 2022.0 1841.0 1827.0 2466.0 2249.0 2932.0 2524.0 2798.0 2749.0 2884.0 2739.0 2214.0 2846.0 2903.0 2038.0 2879.0 3446.0 3286.0 2438.0 2431.0 2659.0 2812.0 2613.0 2956.0 NA NA NA NA NA NA NA NA NA NA 1.0 NA 1.0 NA 1.0 NA NA NA NA NA 1.0 NA 1.0 NA -0.15453401171850345 0.05674681648938142 0.08919398863822169 GO:0005739 mitochondrion cellular_component 24.62001748088745 24.193883444915713 24.44225130145676 NA 19.596278235832926 20.516906068987343 25.195258278093355 24.431548100498137 25.233229283232788 25.372201046244804 20.682211632877475 25.47683622859849 25.228541871344 23.846888768308787 21.56878427771776 22.99670797136377 25.33983101113357 24.398321660239873 25.15825733718696 24.75160936749124 23.957911418673984 23.792995169071013 25.362739276482657 19.830542683034924 24.54686322584525 22.849164984422426 4.0 NA 4.0 1.0 3.0 2.0 5.0 4.0 6.0 4.0 4.0 3.0 3.0 1.0 3.0 5.0 4.0 4.0 7.0 1.0 5.0 4.0 4.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.4261340359717387 0.38888541180776515 0.4711931979962048 GO:0005829 cytosol cellular_component 24.932520103231784 21.112112749169704 21.352210566894946 20.1640454798574 21.520427671167315 19.263833535107104 24.772304159933555 22.135571569302392 26.38097596347504 16.862465810666865 25.590301454141784 21.068676912350465 24.87670349656637 18.47447428755361 25.798472575551877 20.865052710720235 23.500782758583327 19.865779050954945 24.835040457689747 23.23445343588817 23.08361838169421 18.81987760902706 25.473819392208252 21.912180313817935 24.60684563556805 19.87456538411978 8.0 2.0 3.0 4.0 25.0 9.0 31.0 1.0 30.0 6.0 28.0 2.0 22.0 2.0 14.0 4.0 30.0 13.0 17.0 2.0 27.0 5.0 20.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.8204073540620804 0.0001748865925420931 0.0008236168584623857 GO:0005840 ribosome cellular_component 30.14653031580698 29.988629779677787 29.62543407385973 29.471810621682014 28.93779091865883 29.69389275594184 29.88648616236381 30.15705236783009 30.54935117702617 30.047251655021405 30.42721065584933 30.300583297415947 30.332622027165485 29.92641678875169 30.467008746609558 30.126387443321022 29.83520775915589 29.75142835133802 30.18961880642992 30.18702888275441 30.020046719229452 29.67749595230379 30.674348196829072 30.297814566824762 30.02331744127955 29.96001940651623 259.0 142.0 187.0 285.0 328.0 276.0 376.0 246.0 354.0 282.0 351.0 178.0 476.0 225.0 300.0 215.0 355.0 329.0 350.0 198.0 384.0 200.0 355.0 292.0 NA NA NA 1.0 1.0 1.0 1.0 NA NA NA NA NA NA NA NA NA NA NA 2.0 NA 1.0 NA 1.0 NA 0.15790053612919408 0.27265646879500405 0.34545713000625894 GO:0005887 integral component of plasma membrane cellular_component 24.95007249011662 22.950110937241725 20.575212037585946 22.185694086174998 19.574570775890557 21.780089771842427 24.67758625133296 22.56052562401836 25.776756505981787 22.452734590233913 25.68615547438155 22.827602399861807 25.44789056703742 22.656125587903656 25.208907810330555 22.977114540344523 24.519855218599442 23.57258871121183 25.00526337726257 23.852959159978447 22.77080256960763 20.8449956006872 25.45840861675888 24.239241141562772 25.65285239198213 22.343005171706587 5.0 12.0 4.0 11.0 18.0 16.0 22.0 11.0 20.0 21.0 27.0 19.0 18.0 25.0 17.0 22.0 39.0 24.0 13.0 10.0 24.0 37.0 27.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.9999615528748969 0.013042519940568903 0.025877686622941164 GO:0005971 ribonucleoside-diphosphate reductase complex cellular_component 20.748062316010575 24.109625421917237 22.101603439229738 23.59305030330469 21.70615890256277 24.500166292022254 19.998092106718946 24.47876394049233 19.24616606422591 24.02490991248452 18.095628327987253 23.27496225222891 20.527670336630205 23.37486234179656 21.044659402868163 24.006899897985345 20.00930388233304 24.280568224422765 21.374344136923774 24.146688833583113 20.16157911540232 24.088220645517712 16.716912612633053 24.787239512267984 21.27269858764245 23.99878597686861 7.0 12.0 10.0 18.0 3.0 14.0 3.0 13.0 2.0 11.0 4.0 9.0 6.0 11.0 4.0 19.0 7.0 14.0 5.0 12.0 1.0 15.0 7.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.3615631059066615 3.225641456243767e-05 0.0005099643033035255 GO:0005975 carbohydrate metabolic process biological_process 31.61540208942009 32.003032993919675 32.044709640478445 31.43116418392665 31.886797538544336 31.981177636302128 31.30677107929555 32.28115296667977 30.80212842712749 31.94598320281265 31.388301091642795 32.20308159909815 31.46599415669044 31.5737979419928 31.88778686809727 32.36510407276198 31.02603767643216 32.06203614437849 32.4234200949678 32.141313783526876 31.90746097335061 32.111264164455726 30.98039881035601 31.71839706362368 31.33331897699432 31.92993321990221 1510.0 1160.0 1463.0 1263.0 1604.0 1874.0 1574.0 1706.0 1867.0 1852.0 1982.0 1180.0 2271.0 1952.0 1617.0 1657.0 2889.0 1977.0 1583.0 1416.0 1541.0 1434.0 1771.0 1693.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 7.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 -0.38763090449958426 0.011074437676156606 0.022291771322328135 GO:0005976 polysaccharide metabolic process biological_process 27.431683345938644 26.75973769532986 28.337564651795567 26.43697284490141 27.498889199104013 26.017133031845606 26.81039122905803 27.46564148377997 26.385664485396905 26.364828729064765 27.586113491608447 27.1373255952143 27.657652646560532 27.149218617625984 27.67476717978836 27.24687189482304 27.04963584049461 25.89089603071663 27.40977102956897 26.695673962997628 26.87209710846412 27.08985363971467 26.329351872222038 25.88309004736445 28.093100946769802 26.59881859365559 114.0 126.0 118.0 73.0 180.0 174.0 183.0 133.0 277.0 152.0 257.0 113.0 240.0 161.0 214.0 147.0 350.0 151.0 142.0 127.0 128.0 91.0 260.0 117.0 5.0 5.0 5.0 3.0 5.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 0.6719456506087838 0.024343383653741054 0.04309296851045225 GO:0005978 glycogen biosynthetic process biological_process 24.30884945433273 23.587927205548212 25.619276955409518 23.356647368837013 24.595393262985173 22.958974553050197 23.683723281326863 24.424206815013523 23.5352956868538 23.16234604231266 24.17732300025496 24.00171993820719 24.503064642641483 23.94567427224483 24.676925210179995 24.03086563941453 24.071624114365548 22.903974349107283 23.525192510809628 23.17594657303714 23.71088649458229 24.07613146665789 22.33080937930397 22.409751850341877 24.768713046220533 23.229221128531407 16.0 15.0 17.0 8.0 23.0 23.0 23.0 16.0 33.0 19.0 28.0 14.0 31.0 17.0 24.0 19.0 32.0 16.0 15.0 16.0 14.0 10.0 31.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.7209222487845182 0.03266344168491133 0.055917661485280296 GO:0005984 disaccharide metabolic process biological_process 25.113620214210574 26.418873347962442 26.503348995187174 26.3155967303054 26.324188071516428 26.540973639075705 24.714261917130624 27.035767314878758 20.801872474524533 26.011827801285683 22.845277445313076 26.537837485547442 24.83169933328277 26.385741636601946 26.443703225009184 27.25364866844139 23.592025392254623 26.127981969394487 25.938793590756067 25.553132674676448 23.482973925550066 26.15261387528208 21.56148564628996 26.381573093469747 22.67446056659817 25.849882104002038 109.0 101.0 98.0 84.0 39.0 127.0 6.0 109.0 28.0 111.0 43.0 80.0 90.0 171.0 35.0 118.0 76.0 84.0 35.0 90.0 13.0 105.0 29.0 94.0 4.0 4.0 3.0 3.0 2.0 4.0 2.0 4.0 3.0 4.0 3.0 3.0 3.0 4.0 2.0 3.0 3.0 4.0 4.0 3.0 3.0 3.0 2.0 4.0 -1.3052531337518687 0.005583616806378765 0.012692811975156102 GO:0005996 monosaccharide metabolic process biological_process 30.498107003411235 31.0219011106208 30.932012164299717 30.435977969677786 30.87047639775968 30.91425884811096 30.39922294228063 31.279796923931354 29.656627213904986 31.102927327276763 30.23440863021585 31.24315631236525 30.118382952704806 30.46631121078979 30.617280025273715 31.29567687813671 30.119452232455515 31.03189060401484 31.156140701387855 31.2392917960539 30.966055220403252 31.211820816368032 29.90738719780764 30.61868919253944 30.141367972269922 31.06542153500525 370.0 166.0 317.0 236.0 484.0 418.0 493.0 453.0 507.0 471.0 527.0 249.0 599.0 403.0 470.0 352.0 777.0 553.0 466.0 316.0 509.0 372.0 453.0 490.0 5.0 3.0 3.0 3.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 4.0 5.0 5.0 4.0 4.0 6.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 -0.5237941072095644 0.00268017172806849 0.006910856026093958 GO:0006002 fructose 6-phosphate metabolic process biological_process 23.404442611406086 25.174308569417292 24.43905536491978 24.990942109442692 23.234160796843373 24.29006854359615 22.432844157105 25.8405885982239 23.14656046852305 24.67478888036421 22.757372330058953 25.57928555041667 23.640982748461642 25.478422848380603 23.874733790820926 25.01367278270439 23.48881426313707 24.84934441043824 22.73755508490003 25.393523399360074 23.267226537238816 25.042196678947395 23.582219528289162 25.320698853869075 23.053150209057737 24.936776692985145 8.0 9.0 7.0 9.0 14.0 10.0 15.0 9.0 15.0 12.0 11.0 8.0 17.0 12.0 13.0 10.0 11.0 12.0 12.0 8.0 13.0 11.0 13.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.7698659580112057 4.146041132679973e-05 0.0005099643033035255 GO:0006004 fucose metabolic process biological_process 24.128678339588014 23.163663460689783 24.062849091242718 19.792587555152682 24.90298186591092 21.09251732740204 24.042433959791666 20.89352706097764 22.80950109595901 21.53121560453136 24.354406825447864 22.39854882664904 23.550571684321817 NA 24.689219990993987 24.21232511383565 24.3663634091639 NA 25.40106732700841 24.25156814427125 22.73617136013173 22.680841353745915 22.394733321477513 24.403353658112678 22.81117740308895 23.51507244341936 27.0 8.0 32.0 8.0 24.0 10.0 16.0 14.0 26.0 16.0 35.0 NA 54.0 28.0 42.0 NA 28.0 24.0 22.0 16.0 16.0 22.0 14.0 20.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.9650148788982307 0.0409456971929358 0.06795243363934027 GO:0006011 UDP-glucose metabolic process biological_process 22.1406855356188 22.09180216901465 21.595522056473442 20.853559468164264 20.666710322213962 20.843985753549205 20.759744784768454 22.284645387506586 21.18288959389216 21.053651369463143 22.97970295772748 22.49450872431416 21.369348202099214 22.978351944972292 22.333975731951107 22.68095356027023 21.911812449609428 21.732608222078767 22.632088042083545 22.42727858535285 21.860742045094966 20.998116628326603 22.841525504444398 23.220109270912644 23.01223432450283 19.392677597707802 8.0 2.0 3.0 2.0 3.0 5.0 6.0 4.0 7.0 4.0 4.0 5.0 6.0 7.0 3.0 5.0 8.0 6.0 6.0 3.0 6.0 4.0 5.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.04888336660415149 0.7728299926844475 0.8146045868836069 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process biological_process 24.457606950203534 25.49415540592048 24.510848029334625 24.6467805411957 25.21860050805814 25.598866537268037 24.096446253696776 26.458086804053 23.421804301780014 25.254950680917663 23.691858874047803 24.685986665656923 24.61407483491589 24.827359708726416 24.84033670993564 25.86442176996417 23.625686534916788 25.74114488920048 25.16395958297865 25.699145722755322 25.01583770642343 25.313615585213785 23.9101412470862 25.287866856769924 23.824573209110685 25.478124507067427 19.0 22.0 20.0 25.0 21.0 35.0 13.0 35.0 19.0 28.0 12.0 23.0 26.0 32.0 17.0 33.0 33.0 41.0 22.0 25.0 12.0 25.0 16.0 32.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0365484557169466 0.0005320055051392492 0.0019244720881558927 GO:0006022 aminoglycan metabolic process biological_process 24.4885655525498 25.91260816989316 24.90956638539207 25.49228912755233 24.78317409941515 25.061572801880164 23.6086417733886 26.635619013732924 24.46943115672157 25.70518874436675 24.270647855348273 26.658409116319586 24.757219071372727 26.5732743550413 24.64671634708971 25.659044564661865 24.57979897236217 25.042997805882894 24.826863483323002 25.747198367281108 23.660597196846194 25.327341963448077 23.905454943359494 26.361667104884162 24.7072066348015 25.21000085649385 54.0 70.0 54.0 63.0 46.0 118.0 42.0 100.0 58.0 101.0 71.0 88.0 46.0 94.0 51.0 76.0 90.0 95.0 53.0 78.0 52.0 84.0 75.0 81.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 3.0 -1.4240426173433605 3.225641456243767e-05 0.0005099643033035255 GO:0006040 amino sugar metabolic process biological_process 24.26894706713271 24.421011791171363 24.33306034587791 23.36134385755384 24.269188928701958 24.679922784055425 23.79495983734598 25.335665164784608 22.46236134367495 24.091087510771853 24.596511556147284 23.813801531747533 24.297480795094003 24.152630684656266 24.643985524261804 24.35028172732425 24.135447294683523 24.409094711884798 25.29951313187507 24.66178904787743 24.023309085131768 24.848941397245113 23.54512130902888 24.224485039497385 24.230102036491804 24.121918689507734 45.0 29.0 46.0 47.0 46.0 56.0 24.0 39.0 43.0 45.0 39.0 34.0 57.0 53.0 46.0 48.0 74.0 53.0 36.0 46.0 33.0 48.0 47.0 45.0 7.0 7.0 7.0 7.0 8.0 6.0 6.0 6.0 7.0 6.0 7.0 6.0 7.0 7.0 6.0 6.0 7.0 6.0 7.0 6.0 8.0 6.0 7.0 6.0 -0.15206472403865234 0.4529203011037244 0.5347630423627702 GO:0006044 N-acetylglucosamine metabolic process biological_process 22.007355322783656 23.18882693802178 21.804286667681364 22.58853187637217 22.019766050581726 23.980152201990403 21.71021588372784 24.18859796078682 21.06160635088899 22.219283734364762 21.58997610722804 22.376284078372255 21.647396278392787 22.83828791642472 22.214483953964216 23.093519997913212 22.577922219025503 22.91481305296425 23.521070250451878 23.381965352998854 20.58688188185186 23.636481284638467 20.640085138740037 22.899599077952857 22.015285702832976 22.58323404359929 11.0 10.0 11.0 22.0 9.0 20.0 7.0 13.0 10.0 15.0 9.0 14.0 14.0 17.0 16.0 14.0 17.0 17.0 6.0 20.0 5.0 12.0 13.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1814716152381237 0.00042856814449695465 0.0016457016748683058 GO:0006048 UDP-N-acetylglucosamine biosynthetic process biological_process 20.1330709261395 21.014949644711663 21.596281530626026 20.159270400420326 20.39964755526209 21.61285620782175 19.747217667887785 19.082454420011675 13.87309519278063 21.419302423355084 16.848534969926213 19.022990939876944 19.66212113443317 20.253965360385497 19.659807474799045 20.42845967424607 NA 18.68519178489442 20.99355259261264 22.33922052254009 20.77415981317265 21.464444395740962 18.733144860181447 20.771610878024152 20.07855184666708 21.961772438742386 3.0 2.0 4.0 3.0 3.0 3.0 1.0 4.0 1.0 2.0 3.0 2.0 3.0 1.0 NA 1.0 4.0 5.0 4.0 4.0 2.0 4.0 3.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8818787185721639 0.12389131916687696 0.17411752963993518 GO:0006066 alcohol metabolic process biological_process 28.53323072756727 28.30053495914948 27.968235185787286 27.83893131202964 28.69658331573645 27.90260454906411 27.944751733420443 27.486083118472013 27.968818163388715 27.936504494246996 28.350792208523817 28.370906714082352 28.632767218960648 27.65465609893552 27.78945620853853 28.27429027252748 26.509367124972712 27.87509174721349 30.399175481282604 29.990757354371535 29.16498098315267 27.957676582221776 27.48045538474895 28.094206025498533 27.177058528774577 28.10178353253817 137.0 110.0 160.0 159.0 180.0 140.0 188.0 109.0 186.0 192.0 210.0 111.0 199.0 157.0 124.0 141.0 375.0 253.0 222.0 140.0 183.0 115.0 174.0 142.0 3.0 3.0 5.0 3.0 5.0 3.0 5.0 6.0 5.0 5.0 5.0 4.0 3.0 4.0 5.0 4.0 6.0 5.0 5.0 3.0 5.0 4.0 5.0 5.0 0.23269576841778772 0.7728299926844475 0.8146045868836069 GO:0006073 cellular glucan metabolic process biological_process 25.450246612942518 24.691872175751964 26.619276955409518 24.4174645069906 25.595393262985173 23.958974553050197 24.683723281326863 25.619660945570306 24.54807526197597 24.31053541382029 25.72927999180764 25.014755518137644 25.507677233834077 24.953726593059354 25.781678742371398 25.234026924709053 25.071624114365548 23.96562569911152 24.918770730514336 24.183988550842557 24.714971394934672 25.206006489382162 23.90310844403101 23.484787651708256 26.13414472430877 24.41683972879609 32.0 34.0 34.0 16.0 46.0 48.0 47.0 35.0 71.0 39.0 58.0 30.0 65.0 41.0 48.0 40.0 83.0 33.0 32.0 36.0 31.0 22.0 66.0 30.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 2.0 3.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 3.0 3.0 2.0 3.0 3.0 0.7583744371905539 0.03766692222862868 0.06276144050911694 GO:0006081 cellular aldehyde metabolic process biological_process 26.65424273171589 27.126079495262488 26.09066956087841 25.874032623177985 25.78048136297069 27.56908842415913 26.02179135327205 27.20325781414168 27.074938937602482 27.725770062748857 26.487953690922524 27.30833214557456 26.819539862656285 26.538360679872678 26.83229222182302 27.142561274260203 26.22804603884323 26.682009668018164 27.443294267327328 27.288163882398877 26.922364264652728 26.94310974640235 26.93590201136005 26.78941741462767 26.254756700193035 27.517967126342306 45.0 36.0 34.0 33.0 58.0 70.0 88.0 79.0 74.0 80.0 90.0 57.0 83.0 62.0 66.0 72.0 127.0 91.0 73.0 52.0 86.0 73.0 71.0 68.0 1.0 5.0 6.0 6.0 3.0 5.0 4.0 3.0 6.0 6.0 3.0 3.0 4.0 6.0 4.0 6.0 6.0 4.0 6.0 3.0 4.0 6.0 4.0 5.0 -0.4718367635465981 0.03266344168491133 0.055917661485280296 GO:0006082 organic acid metabolic process biological_process 33.23504281962214 33.269590967611045 32.84119414469689 32.44184996890897 32.595238237441485 33.07573928920356 32.93833949167961 33.23921403662509 33.09941322215278 33.077011205208876 33.49925165284942 33.497348602254625 33.388097423480026 32.8996590853486 33.618538854579285 33.606936551520924 32.744112011186836 33.724733741203146 33.837760641410796 33.54558534904365 32.79474949007937 33.01428272799069 33.515261867153534 33.51357902665245 33.337792780442015 33.111222136432126 3921.0 4340.0 4631.0 5833.0 4611.0 7231.0 5295.0 7036.0 6191.0 7336.0 6544.0 5543.0 6412.0 7349.0 4469.0 7932.0 7765.0 7612.0 5730.0 5993.0 6337.0 7024.0 5737.0 7098.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 -0.034548147988907374 0.6861059569955559 0.7413508522341591 GO:0006084 acetyl-CoA metabolic process biological_process 27.633767692894 26.25788909123856 25.900890260575014 23.518808586189714 25.45610979140469 23.61235842946867 27.46711927735373 26.296619645381288 28.096922211874343 27.405231281871785 28.141899185007485 26.51291364539645 28.00725491897707 25.50856946063196 27.980668523110623 25.677884630221854 27.341232628458535 26.32189039046497 27.657725296554 26.686908739360927 27.265308407295986 25.878025123533536 27.860443480692073 25.59880515927528 28.161020938829733 27.393732352918573 51.0 14.0 31.0 13.0 81.0 53.0 93.0 41.0 80.0 53.0 80.0 36.0 84.0 45.0 65.0 39.0 105.0 83.0 64.0 34.0 90.0 48.0 83.0 41.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 3.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 3.0 2.0 2.0 2.0 1.0 2.0 1.0 1.3758786016554403 0.00268017172806849 0.006910856026093958 GO:0006085 acetyl-CoA biosynthetic process biological_process 26.905076338188127 24.99081336552803 24.95724017162632 23.49429624524351 24.126767803609447 23.44099318876204 26.79141705542053 25.320900920893077 27.567055169736854 25.68387988498505 27.698575492529308 25.325606742794037 27.28457028979421 24.604580684972486 27.488151654351352 24.518862544433517 26.282600102240878 25.231522766686698 26.82806716474011 25.59874876900699 26.03084983926933 24.67803270749764 27.08924017489245 24.190855175045236 27.257905021236052 25.666916682114426 30.0 13.0 16.0 8.0 51.0 37.0 54.0 25.0 46.0 34.0 45.0 22.0 50.0 28.0 37.0 27.0 74.0 56.0 37.0 20.0 47.0 30.0 51.0 26.0 NA NA NA NA NA NA NA NA NA 1.0 NA NA NA 1.0 NA NA NA NA NA NA NA 1.0 NA NA 1.9142629726600973 0.0012242832644312096 0.0037265988146589013 GO:0006090 pyruvate metabolic process biological_process 28.74983446731285 29.69444712438939 29.14641376421565 28.88151000846227 28.65458682605389 29.65186022179433 28.259976918420826 29.905730647374906 28.10032467603891 29.76419127396823 28.835590843952733 29.575127323981533 28.599556219929518 29.023045464678287 29.479433194150854 30.023559936082247 28.328681328917607 30.278293374450143 29.40298140489693 29.89393755327536 28.49859630090268 29.57504270873887 28.298296074952965 29.61737825471084 28.576116178019376 29.593123011153306 129.0 93.0 127.0 139.0 162.0 218.0 214.0 217.0 217.0 193.0 189.0 130.0 231.0 174.0 183.0 197.0 273.0 212.0 186.0 170.0 207.0 166.0 176.0 197.0 2.0 1.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 2.0 -0.9446126570765401 0.0001386794054294884 0.0007006959432226783 GO:0006091 generation of precursor metabolites and energy biological_process 29.620553192124767 29.850706163746533 29.356179667305078 28.91265907331935 28.7361549686437 29.661903681529875 29.331008487654554 30.05325475747281 29.446739273008014 29.94328418856297 29.897163036543105 29.75688307701923 29.93018863961639 29.092251149862772 30.237001669644798 30.12418198168341 29.587599689867982 30.381832382472876 29.836559721487642 30.050732688066372 29.650406658912612 29.74927408453313 29.224942628490314 29.604778302214278 29.645194673223767 30.204238948399038 167.0 109.0 141.0 148.0 272.0 241.0 304.0 221.0 311.0 228.0 284.0 142.0 363.0 209.0 251.0 220.0 423.0 259.0 278.0 207.0 287.0 164.0 285.0 241.0 3.0 3.0 2.0 2.0 3.0 3.0 4.0 3.0 3.0 3.0 4.0 4.0 4.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.2301529716217665 0.11903289845700783 0.16804644488048165 GO:0006094 gluconeogenesis biological_process 27.49557867818193 27.91874706196195 27.83888210519432 27.08320887271524 27.417701758136424 27.49379923248075 27.325191104721327 28.118415612378982 26.74838913555105 28.066871371754818 27.36500134329369 28.64386002343551 27.25904828907053 27.473807866646986 27.369129514519585 28.22122472703531 26.951575260164994 27.993765538044162 28.076743901295018 28.03267570847373 28.357916784578038 28.163495766824703 27.271736469489163 27.342997399164428 27.109118497294283 27.642825586254965 63.0 23.0 50.0 37.0 95.0 83.0 106.0 97.0 103.0 98.0 100.0 50.0 107.0 69.0 84.0 73.0 167.0 108.0 103.0 57.0 113.0 68.0 97.0 104.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4231683837800233 0.02824036873330045 0.04901805310036017 GO:0006096 glycolytic process biological_process 28.363931975813827 29.53780276552257 29.031302068453822 28.88151000846227 28.64851955054902 29.64693607295549 27.70537282949156 29.76751902053936 27.148406031846843 29.371779983024112 28.20138105499236 29.301279692038456 28.00184600940581 28.84014311112464 29.214507588574637 29.94769524398561 27.782683313560373 30.1492008229564 29.16270559016053 29.75627546528489 28.162150263730013 29.462312242059394 27.589292681683173 29.490646698966852 28.029170921560826 29.253193264118988 98.0 93.0 119.0 136.0 100.0 162.0 116.0 136.0 119.0 130.0 101.0 88.0 153.0 129.0 104.0 137.0 181.0 143.0 131.0 127.0 117.0 116.0 102.0 128.0 NA NA NA 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA -1.1738707897087437 0.0001386794054294884 0.0007006959432226783 GO:0006098 pentose-phosphate shunt biological_process 24.70167841886849 25.77828864116108 24.76813539001111 25.807013089359703 25.072583493716305 25.627213614946065 23.98239952807497 26.146356658230147 23.69070592249135 25.6696527054435 23.652648119770646 25.669866130673928 24.438328672402353 25.74663500886777 24.737002382858392 25.556842747345023 24.092381006026176 24.813427005972517 26.296909418407363 26.193235529826538 24.95913422537656 25.761431266467525 24.341322364939103 25.7497720532094 23.874331629094662 26.138067611695785 21.0 32.0 19.0 19.0 20.0 34.0 21.0 36.0 19.0 37.0 30.0 32.0 38.0 31.0 20.0 25.0 52.0 43.0 25.0 26.0 25.0 34.0 20.0 28.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0766102222925902 0.0008121171348941295 0.002709952364566507 GO:0006099 tricarboxylic acid cycle biological_process 27.651748393604546 25.672293991607777 25.961469703714823 20.714337831087263 24.57040812358334 24.23558889073343 27.24122257153273 25.16724600876681 26.44581996493217 26.326995135194 27.661136358262482 26.98461026407337 28.15657482794137 24.52758206218749 26.760947502319212 24.78810681874409 26.469145143339734 25.31907942076648 29.201554097169605 26.09948099514773 28.53499051982772 24.697042967452298 28.054665120202056 24.83707732432127 27.4776535927196 27.075790668637037 43.0 6.0 24.0 26.0 57.0 26.0 72.0 41.0 75.0 64.0 74.0 16.0 53.0 17.0 46.0 33.0 104.0 55.0 86.0 17.0 89.0 27.0 60.0 46.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.9794544019967688 0.0022136919545913893 0.006045268182341475 GO:0006107 oxaloacetate metabolic process biological_process 22.376120338435683 25.419443455271985 22.93968673196653 24.63003565933396 23.973919587407106 25.05091969828096 21.11963913383804 24.753847450639075 21.66757874116848 24.019506629536252 21.123052963865053 25.38678404643379 22.8901693720638 25.84089121183173 22.48114641471352 26.364254576423477 20.58158264960056 26.163930769900322 21.477124612077308 25.04592520730937 22.608931275743586 24.90367893840459 19.372467914453832 26.14106070429623 22.879281526592607 24.68227890835784 18.0 49.0 37.0 51.0 7.0 46.0 5.0 47.0 10.0 47.0 20.0 46.0 17.0 69.0 8.0 58.0 18.0 46.0 23.0 59.0 2.0 62.0 28.0 50.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.0433231168363015 3.225641456243767e-05 0.0005099643033035255 GO:0006139 nucleobase-containing compound metabolic process biological_process 34.92618248896371 35.752416375104154 35.119872183305944 35.13332373885157 34.78353400171482 35.70010139918462 34.542142020472305 35.923017837498676 34.446243809748744 35.65583118623832 35.06751350419659 35.642044373113606 35.04158462717141 35.30877599576352 35.32865623352167 36.120470741148274 34.47453463955261 36.18323156534585 35.486140367064365 35.928570545013805 34.90370657546538 35.62368398926572 34.61939851672025 35.850456552036064 34.8684535918214 35.61430341117101 16735.0 17055.0 16501.0 20730.0 18380.0 26806.0 20562.0 24768.0 21452.0 24913.0 23126.0 19280.0 22913.0 25293.0 18149.0 25931.0 28565.0 27407.0 21175.0 21388.0 21783.0 23585.0 22187.0 25320.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.826233886140443 8.637667594722788e-05 0.0006159890947550879 GO:0006144 purine nucleobase metabolic process biological_process 24.23400518416767 25.829511443665762 25.2653885889947 25.91228362120071 24.679664856715803 26.625860725858328 23.72183782545207 25.47265369412096 23.034578402676463 25.522571322852468 24.44285807074738 25.4585609712974 25.154013227907214 25.8686813159526 24.07336075382121 26.19992315944532 23.290037631482853 25.32298106173394 22.920497159561318 26.056688997813698 24.01125785528329 25.895636942791004 23.903723829720867 26.18737804190684 24.145485456852683 24.179449198244185 24.0 37.0 18.0 33.0 18.0 36.0 19.0 39.0 21.0 34.0 27.0 30.0 27.0 46.0 12.0 36.0 23.0 43.0 21.0 36.0 14.0 25.0 14.0 30.0 4.0 2.0 2.0 2.0 4.0 2.0 4.0 4.0 4.0 4.0 4.0 2.0 4.0 2.0 2.0 2.0 4.0 4.0 4.0 2.0 4.0 2.0 2.0 5.0 -1.5955062594980909 8.637667594722788e-05 0.0006159890947550879 GO:0006163 purine nucleotide metabolic process biological_process 31.650330000032486 32.44625009915746 31.832985949854606 31.794400358511144 31.466692649244624 32.406120935682566 31.31262769834055 32.632694059431245 31.245842852501998 32.35714816792748 31.808787549713397 32.2997387276345 31.732860734842486 31.90978860420381 32.137883423168674 32.853755091968786 31.205372044052762 32.947284568250424 32.19413711804338 32.624343768628684 31.50126476586636 32.34225894780096 31.32879307034264 32.45676831083243 31.60078184296417 32.30897426175865 1420.0 1345.0 1492.0 1716.0 1611.0 2225.0 1793.0 1962.0 1826.0 1941.0 1873.0 1424.0 1981.0 2082.0 1547.0 2050.0 2389.0 2267.0 1798.0 1828.0 1789.0 1730.0 1816.0 2005.0 2.0 2.0 2.0 2.0 4.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.7959200991249737 0.0001386794054294884 0.0007006959432226783 GO:0006164 purine nucleotide biosynthetic process biological_process 29.670939280447968 30.43514182785337 29.780246234833065 29.82000113728764 29.400934841841607 30.34868791515908 29.46950523694907 30.608216299728014 29.32757911526955 30.356410277407075 29.88626955209933 30.316414784934906 29.86231647702364 29.960385585660127 30.02055812369978 30.846300800837327 29.24691863507373 30.889334996446962 30.167253605002628 30.58977968871329 29.53985635365123 30.31710707715272 29.389762344836026 30.485197975575126 29.619573436348237 30.315949202011648 413.0 400.0 419.0 494.0 464.0 636.0 509.0 582.0 526.0 571.0 552.0 423.0 550.0 615.0 446.0 602.0 667.0 666.0 508.0 532.0 509.0 507.0 528.0 602.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.7642025474054037 0.0001386794054294884 0.0007006959432226783 GO:0006166 purine ribonucleoside salvage biological_process 23.08364600842668 24.998233186953765 24.296386034387805 25.202944800937924 23.344261084754592 25.15213884276711 22.220525575560327 25.01835786971194 21.784989515699472 24.89446553737893 22.83659991049699 24.532612946227502 23.92360909477625 25.254339760652503 23.06314204652435 25.059392911359076 21.892631823210696 24.390527597075817 23.29129375765464 25.12353084443161 23.3299007036969 24.811105672175998 22.114381936180234 25.715560498876 22.393446481411843 24.159531189924607 14.0 24.0 8.0 14.0 13.0 22.0 11.0 26.0 14.0 22.0 14.0 20.0 14.0 24.0 11.0 22.0 21.0 26.0 12.0 19.0 8.0 21.0 10.0 24.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.9145871785270856 4.146041132679973e-05 0.0005099643033035255 GO:0006167 AMP biosynthetic process biological_process 26.165776220060195 26.77494687114128 26.221928450711307 26.28114037874309 25.767071964020356 26.31506609618368 26.679868057912664 26.77329982997629 25.795585751197834 26.849397851305607 26.49689144364427 26.77124291712241 27.049015840819955 26.803116114362005 25.54931289934585 27.267789340324445 25.77392907616485 26.926415575117787 26.30245273052153 26.81818670115847 25.68235751250499 26.603106621337822 25.92411263938449 27.02535335496388 25.88414004602209 26.571114072637343 73.0 62.0 61.0 69.0 60.0 83.0 52.0 89.0 72.0 92.0 88.0 74.0 69.0 99.0 64.0 94.0 77.0 105.0 69.0 81.0 68.0 86.0 76.0 95.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.6091706510810866 0.0018227351663913985 0.005134928866041682 GO:0006168 adenine salvage biological_process 22.19978246988749 24.191307066268376 23.63384511765479 24.305885827220074 23.094702355994645 25.03481318347837 20.910744135655868 23.826666546593962 21.016220711882802 23.83732870481532 21.79148455711656 23.72787418579436 23.46157815828225 24.26827192660029 22.048733028257903 24.570179418489452 19.949270338379762 23.67480819339753 20.684506909767485 24.348431064044448 22.307118032987297 24.283607607637812 20.819547709121345 24.59795582260665 21.24388683039904 22.342746334888425 6.0 10.0 6.0 10.0 4.0 10.0 4.0 9.0 5.0 8.0 8.0 9.0 6.0 13.0 3.0 10.0 4.0 10.0 5.0 10.0 1.0 8.0 4.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.9915245963808843 6.784570247173055e-05 0.0005498145239267514 GO:0006177 GMP biosynthetic process biological_process 24.917914141460475 25.987554706222976 25.165919366239446 26.00216106880107 25.60333944974535 25.97597436968152 24.33181697539865 25.949829079622802 24.13033892193661 25.506036064237215 24.553193120717047 25.670093161559137 25.353181434613127 26.041725241752356 24.576191740359093 26.001410850016466 24.53580775895032 25.874135555905852 24.40439703896241 26.561805739726672 25.533813280013856 25.789504485933875 24.952171740941896 25.941151036667506 24.94159517413875 26.25495726602384 31.0 27.0 45.0 53.0 23.0 47.0 34.0 43.0 28.0 41.0 38.0 30.0 34.0 46.0 24.0 48.0 36.0 36.0 47.0 46.0 34.0 39.0 30.0 53.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0696405647625014 5.312128159411724e-05 0.0005099643033035255 GO:0006188 IMP biosynthetic process biological_process 24.929413672934718 25.791575610790137 24.673495517178768 25.4532267707199 24.290545700984808 24.594905695511518 24.8231775512642 26.221959561954346 24.76703431713805 25.601408185805173 25.639596898161024 25.545778851814465 25.779098529659525 25.949857084715482 24.454237827682682 26.492731689333425 25.15343012388985 25.958701183856643 24.18064425575356 25.729616751200943 23.767381791891466 25.771593821154145 24.373936623381514 25.96542015411314 25.651762469331945 25.411646231846237 27.0 57.0 34.0 42.0 54.0 92.0 45.0 80.0 63.0 67.0 73.0 56.0 46.0 97.0 66.0 90.0 64.0 78.0 40.0 67.0 50.0 58.0 74.0 72.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.8621619378554186 0.0032349119169146935 0.007931571851295751 GO:0006189 'de novo' IMP biosynthetic process biological_process 24.817292907124155 25.399740055163086 24.210944525325665 24.74182033026864 24.15882040283277 24.41877375744225 24.73592429610796 25.818214951818447 24.71243386608553 25.12461835409148 25.600633163319696 25.271284763163628 25.736656414581013 25.43325642079565 24.16474445957937 26.3302946395684 25.08469545290389 25.764347628689386 23.90919293584423 25.27250781051021 23.586365443634023 25.52836899135879 24.302104845199203 25.10255392922885 25.602818207061237 24.969505025975128 20.0 43.0 31.0 38.0 48.0 80.0 40.0 66.0 57.0 56.0 70.0 46.0 39.0 86.0 60.0 79.0 52.0 63.0 36.0 59.0 46.0 46.0 70.0 58.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5824471480389306 0.02092133533779403 0.038284203081476474 GO:0006206 pyrimidine nucleobase metabolic process biological_process 27.130691982154797 27.13687651450941 26.88067323267003 25.90191390239555 25.972509193027967 26.419853178634074 26.640377188590346 26.99698004790935 26.89893889385756 27.59507509329061 27.72830631745779 28.0759044279873 27.69323130697009 27.12844779717163 26.74683988571844 26.6452163095574 26.79038067261056 26.758170916579576 27.255591793387577 27.02688095788852 27.572624336111478 26.97644094635041 27.53965586116707 27.61170255382041 26.85253569781775 27.25130337492887 65.0 50.0 38.0 63.0 85.0 88.0 119.0 105.0 87.0 102.0 101.0 71.0 113.0 64.0 98.0 91.0 119.0 105.0 86.0 65.0 113.0 90.0 103.0 87.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 -0.006184532354613026 0.9539596927720386 0.9577970205788449 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process biological_process 26.07392149050803 24.466173130505506 25.605144626267897 21.02865519180053 17.789742004959546 18.335906308938643 25.43857766240068 23.617060888734738 25.61950554145176 25.33972292187776 26.612573917512783 26.75097587675684 26.86307873892716 24.70643965594461 25.9910450752068 22.34394101391004 25.559858602989202 22.90706657434892 26.511524604011804 24.618292632412235 26.454827502454943 23.855294804716806 26.87820007558616 21.70302189829507 25.502037141665763 24.42162450256536 13.0 6.0 2.0 3.0 19.0 25.0 30.0 27.0 25.0 23.0 28.0 24.0 39.0 16.0 25.0 18.0 26.0 17.0 27.0 19.0 29.0 11.0 29.0 30.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.6077483600025246 0.0032349119169146935 0.007931571851295751 GO:0006213 pyrimidine nucleoside metabolic process biological_process 23.38028711135786 21.28983450569623 20.455003290695114 19.173269044132315 25.261919534232593 23.673480951312694 21.535037104464326 20.72100308342545 17.15968672646526 18.22771577290958 20.241209718887387 21.644623963498958 21.863110447490786 19.563903776419394 22.39971930089748 19.699849696821662 NA 17.101942562683504 24.99672664922606 22.556146430733786 23.25350499920861 20.059337207127854 24.214638652446684 20.246773066279303 20.708740529669736 20.206382774619392 5.0 2.0 21.0 22.0 5.0 8.0 1.0 2.0 1.0 2.0 15.0 4.0 4.0 5.0 NA 3.0 16.0 12.0 17.0 6.0 21.0 8.0 3.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 1.0 NA NA NA NA NA NA 2.0904526056616284 0.036388866200708525 0.0618709877636025 GO:0006220 pyrimidine nucleotide metabolic process biological_process 28.451346099296398 28.83515295777543 28.1171666781686 28.03987466355739 27.528779292178093 28.31203616872766 27.90867585480915 28.784182727836466 27.897528826473426 28.972045685957042 28.801548603578482 29.17177561569878 28.900986600468357 28.889289136963672 27.846507148649 28.81767875722457 28.162960535922107 28.658265515570807 29.024915969372483 28.750993201019163 29.16497639733154 28.515731319967376 28.308137681253623 29.590465751650015 28.66677449498429 28.914791011081768 333.0 355.0 213.0 359.0 366.0 535.0 394.0 573.0 432.0 612.0 572.0 481.0 443.0 494.0 419.0 604.0 605.0 582.0 441.0 371.0 537.0 632.0 559.0 597.0 3.0 4.0 4.0 3.0 5.0 3.0 5.0 4.0 4.0 4.0 4.0 4.0 5.0 3.0 3.0 3.0 4.0 4.0 4.0 3.0 4.0 3.0 4.0 4.0 -0.3838068584790335 0.0734883472918226 0.11239394291690516 GO:0006221 pyrimidine nucleotide biosynthetic process biological_process 27.253137944504928 27.597501186460928 26.95205494386739 26.75395828375288 26.32919215057075 27.092848139133768 26.727583474813752 27.526345746269026 26.675832544572515 27.76368159699746 27.62052611874922 27.964958461154666 27.63694863442948 27.61388949140117 26.51628130428329 27.527026718527328 26.93364182973641 27.39774176003119 27.882530891343325 27.524402249646787 28.082821046052718 27.33584271357623 27.06266843510964 28.34451579700963 27.39019773032584 27.70368482887879 137.0 136.0 86.0 144.0 151.0 196.0 162.0 215.0 176.0 241.0 227.0 174.0 175.0 185.0 171.0 230.0 246.0 229.0 181.0 143.0 220.0 246.0 225.0 232.0 3.0 4.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 3.0 3.0 4.0 4.0 4.0 3.0 4.0 3.0 4.0 4.0 -0.34436324195599965 0.0940685547103812 0.1379524750629327 GO:0006222 UMP biosynthetic process biological_process 25.639979576503826 26.11796581464353 25.414754041146068 25.227873148593755 24.49356057030096 25.330718979781185 25.224309662032336 26.018669066370958 25.105034994958682 26.257363837574268 26.036640272862293 26.491023183638138 25.927528682012404 26.27515468994195 25.22278852254475 26.14699761536352 25.50422417026763 26.081765706802123 26.074816176232122 25.94868522754935 26.375753917593823 25.74546629859023 25.08380427744277 26.837735432466435 26.083256136558386 26.296376099235648 42.0 52.0 23.0 45.0 50.0 95.0 56.0 95.0 55.0 92.0 71.0 82.0 73.0 74.0 65.0 101.0 67.0 80.0 50.0 57.0 62.0 97.0 79.0 91.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.4779862381397031 0.024343383653741054 0.04309296851045225 GO:0006223 uracil salvage biological_process 24.49607247662366 25.28599044916409 24.49206697498928 24.251510663322826 23.612931587881395 24.747098520285192 24.18637898673121 25.2427610021698 24.534757768638944 25.64992905794559 25.22984593693209 25.728179537370696 24.844674300254358 25.212986393990544 23.607682426922484 24.985158004724546 24.400468846094657 25.057581917084608 24.29379193305467 25.137659954034056 25.0452109403264 25.213534395035357 24.287171420673623 25.984903107588725 24.519834320652517 25.44280262342195 16.0 14.0 9.0 17.0 21.0 18.0 28.0 24.0 20.0 26.0 21.0 14.0 24.0 16.0 24.0 23.0 29.0 29.0 17.0 15.0 24.0 24.0 24.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7899179725404295 0.0018227351663913985 0.005134928866041682 GO:0006235 dTTP biosynthetic process biological_process 20.998607609339174 21.659201110192576 20.513115815480667 22.006389878084608 20.59374528802953 20.746910490735775 19.60112413997934 20.79507190616565 19.64749936672032 21.131580530058624 21.50542959340311 21.44762529976339 22.66443928190364 22.150473784456054 16.357758211824393 22.086028441528764 19.638139093831164 21.75792611586859 20.500283870251657 22.277049223897553 20.675873174265195 20.38980463000753 22.072668860905274 22.062400115581607 21.16545407512552 21.655257995180907 8.0 13.0 6.0 9.0 4.0 7.0 4.0 9.0 7.0 16.0 14.0 15.0 2.0 13.0 2.0 14.0 9.0 14.0 6.0 6.0 9.0 12.0 11.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6605935008534018 0.02824036873330045 0.04901805310036017 GO:0006241 CTP biosynthetic process biological_process 24.3748616313955 25.02417631139236 23.62545299909129 24.448365062563525 23.358607914178904 24.888425117617444 23.501847819665517 25.09076792537257 23.828822556303912 25.106849288188428 24.55416899718145 25.18291986451677 25.08959091448504 24.908723750600466 24.35737121403022 25.162734447570877 24.12930690907227 24.668249268540567 25.10562927363682 24.887350044733097 24.39413031009704 24.64729078297276 24.67702433653304 25.89477438349473 24.600057320009345 24.84476239767354 24.0 27.0 15.0 31.0 22.0 43.0 27.0 50.0 32.0 44.0 43.0 34.0 33.0 44.0 26.0 44.0 56.0 48.0 42.0 33.0 45.0 52.0 36.0 50.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.6493146799968592 0.00268017172806849 0.006910856026093958 GO:0006259 DNA metabolic process biological_process 26.988970792316326 27.54792287162505 26.355104422993932 27.363757080060005 26.0311149995136 27.52569673203972 26.984521997682833 27.558167568165736 26.45524059804223 27.072083322885398 27.428161026312605 27.38204734222293 27.26586732248487 27.80748609846518 26.317102848753148 27.728080608225042 26.628830736784266 27.28272856209545 26.974115972861377 27.789699981942416 27.967416721805602 27.10954846055398 27.108337381888884 28.11236187077457 27.168452368624806 27.48320325472791 179.0 265.0 166.0 284.0 245.0 310.0 250.0 256.0 336.0 296.0 342.0 407.0 222.0 360.0 198.0 300.0 253.0 337.0 197.0 196.0 235.0 379.0 339.0 304.0 8.0 9.0 8.0 7.0 10.0 7.0 9.0 7.0 12.0 9.0 12.0 10.0 9.0 9.0 10.0 8.0 9.0 11.0 11.0 7.0 10.0 10.0 10.0 8.0 -0.5589520793087246 0.0032349119169146935 0.007931571851295751 GO:0006261 DNA-dependent DNA replication biological_process 24.71742601803152 25.279151572605052 23.92936470402384 24.936340707631267 23.87709752294389 25.71371912985073 25.32736751185779 25.038449361797024 24.65394094620613 24.868851671652266 24.96629424777299 25.107939968607532 25.29539702760448 25.65032018994868 24.54245607032908 25.680891167450863 24.281248157500137 24.480178003954386 24.89296293779035 25.42281045232842 24.667616529815263 24.73833783864609 24.825273513629732 25.61393446023039 24.565820541711226 25.456191877491346 44.0 62.0 44.0 74.0 67.0 78.0 65.0 70.0 70.0 74.0 86.0 72.0 64.0 93.0 54.0 75.0 69.0 82.0 70.0 65.0 67.0 90.0 71.0 88.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5617255545735311 0.006656727227605034 0.01478219854101616 GO:0006265 DNA topological change biological_process 22.943827160883234 22.33426191158937 22.053424155635856 22.56936988084907 20.533306904410324 21.66310346807064 23.68058742322669 22.035180727168804 23.127030922092622 21.793944218642764 23.39465871515061 22.372097713570586 23.66789639776539 23.100540483021287 21.81654155297362 22.534805836317787 22.056327465038986 21.343207372151653 23.812380224384324 22.295411698346573 21.96551518577983 20.573690994956184 22.912220692611193 23.34542096200128 23.135255283034287 22.378070170508266 7.0 9.0 6.0 8.0 24.0 8.0 20.0 10.0 31.0 9.0 31.0 11.0 13.0 6.0 11.0 7.0 41.0 15.0 14.0 8.0 22.0 7.0 28.0 17.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.6095652492938655 0.13332693177434943 0.18549833985996442 GO:0006269 DNA replication, synthesis of RNA primer biological_process 20.68787196621764 21.52224337993729 20.99954503481394 21.31725484443333 21.276390670831336 22.65467563937553 20.493954721259943 20.78281017409428 19.717243849686625 20.82980221437668 21.327316504955867 22.390097574621702 21.801103096631266 21.978871788848128 21.315122445408573 20.607771360413686 15.532618974349509 19.985683723648904 18.880528620956973 21.143235082328328 20.90257050583245 21.15609232590446 19.09061495813206 22.2589976962158 20.36639628911957 20.3333311985342 5.0 8.0 3.0 11.0 3.0 7.0 5.0 11.0 8.0 9.0 8.0 10.0 6.0 11.0 2.0 5.0 5.0 12.0 5.0 4.0 3.0 11.0 8.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8343714137196514 0.10596880912720232 0.15148805703407617 GO:0006281 DNA repair biological_process 24.87622794583509 24.79308510340623 24.168881674259854 24.52801754151904 23.599142477318672 24.836731246219987 24.20936548875721 24.39191673584936 24.594949764354038 23.94738476503214 24.821849804114308 24.573955959463678 24.660687798415022 25.23410242708752 23.879051312415395 25.104332617437606 24.2526324483354 24.637645351905128 24.36924845508038 24.753260178818888 26.92013977740307 24.359080824017248 24.397924772594266 25.66003107347661 24.880245502686574 24.69052682722436 41.0 56.0 44.0 64.0 49.0 55.0 77.0 47.0 90.0 59.0 76.0 121.0 53.0 83.0 48.0 67.0 45.0 68.0 31.0 37.0 55.0 102.0 94.0 54.0 4.0 5.0 3.0 4.0 5.0 5.0 3.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 3.0 4.0 6.0 3.0 3.0 3.0 3.0 5.0 4.0 0.08314284242885961 0.16585666034291002 0.2267131567447445 GO:0006289 nucleotide-excision repair biological_process 20.585689725129715 21.208186823052962 21.51053586751598 19.975798287784688 20.940754330929348 21.50219233074285 22.11441383142952 20.53294174996003 19.505035086542453 19.59014567197336 20.9129845648158 21.78042889288569 20.918839602381038 21.89664693973113 17.237365273395017 21.511360336970306 19.21239689948567 20.510189137088684 20.00967386775765 20.82996511414353 17.686721148562576 19.4999168238156 17.596878960198953 22.5710905266035 21.203820754995014 20.886676735036755 8.0 4.0 11.0 10.0 2.0 8.0 7.0 6.0 10.0 12.0 5.0 12.0 2.0 11.0 4.0 11.0 7.0 8.0 3.0 4.0 3.0 20.0 11.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6224970979232474 0.2253456937016668 0.2954111614912607 GO:0006298 mismatch repair biological_process 21.22827219469906 19.945101659797245 NA 18.03462078234055 NA 19.94116258919583 20.609115686339205 18.51655992787191 22.349911159778728 19.295909282703555 20.735527537328867 16.268392387487115 21.08225319594188 21.1479608156108 21.611212889867268 18.2370835946985 20.832047320342923 NA 17.05304768262557 17.676300024329166 NA NA 21.43828670234348 21.8838932473728 21.587459191472067 NA NA 2.0 NA 3.0 7.0 2.0 20.0 3.0 9.0 1.0 9.0 8.0 12.0 2.0 8.0 NA 1.0 3.0 NA NA 14.0 6.0 17.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.2831705349018137 0.05763072439476858 0.09024233882643813 GO:0006304 DNA modification biological_process 24.009242715650053 21.594178572974702 21.99224599922459 22.58270148433315 19.153823918500176 21.749431754660424 24.49822823835497 22.254553219241767 20.160969737469717 20.06383226395612 25.56721953002877 18.631399885579526 21.80318472187521 23.18192367829675 20.89217881480815 21.525240316640183 24.34701223548189 20.76966507773384 22.75763664729229 21.389067331534807 NA 20.472064399324093 25.176135150718608 19.55247514730099 25.037846011958948 21.186248174044604 15.0 19.0 5.0 19.0 29.0 27.0 7.0 4.0 27.0 5.0 29.0 34.0 8.0 27.0 14.0 12.0 4.0 7.0 NA 6.0 10.0 5.0 45.0 12.0 2.0 4.0 3.0 4.0 3.0 3.0 4.0 4.0 4.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 2.0 3.0 NA 2.0 2.0 3.0 3.0 3.0 2.4150641426753516 0.04889984922191003 0.07872902492059129 GO:0006306 DNA methylation biological_process 22.95830177703745 20.213064733716358 20.971711058220013 21.180740317888386 18.001212309895386 19.56153109762818 23.47051188068396 20.976757560023998 16.59470552957062 15.317406712657885 24.530455121072425 14.926970037753096 20.09303317717432 22.177122057883714 19.60097209895803 19.707106656067875 23.319845848459085 19.27043140973939 21.75763664729229 20.00455699128732 NA 19.472064399324093 24.16661639937965 18.112529198983665 23.985632896336337 19.940203374409574 7.0 8.0 2.0 5.0 13.0 13.0 1.0 1.0 10.0 1.0 9.0 16.0 3.0 9.0 5.0 5.0 2.0 3.0 NA 3.0 4.0 2.0 19.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.74523704332109 0.042254020654422304 0.06966052546462224 GO:0006310 DNA recombination biological_process 24.376611651526602 24.586883614599422 24.17135328565033 24.628429620122628 24.207693154230014 24.50437792747991 23.66307439936389 24.30798584739809 23.350719252419978 23.66428325455035 24.34581315106212 24.10448938409441 24.72696554085813 24.902937463156015 23.690392345009734 24.70682287818836 23.772925620771762 24.626588833698072 24.60918687390293 24.953576285458432 25.67996937346053 24.30249344397685 24.378719131413774 24.98931786524857 24.32440042731941 24.809774022317672 26.0 27.0 28.0 35.0 22.0 28.0 23.0 23.0 39.0 28.0 35.0 52.0 24.0 35.0 20.0 37.0 31.0 36.0 32.0 18.0 30.0 46.0 31.0 32.0 1.0 1.0 2.0 1.0 1.0 2.0 NA 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 1.0 1.0 1.0 1.0 1.0 1.0 2.0 1.0 2.0 -0.21027196307282026 0.0940685547103812 0.1379524750629327 GO:0006351 transcription, DNA-templated biological_process 27.605853104269208 28.102752529297558 27.429879093170833 27.532002073665854 27.00190554347583 27.57417311665068 27.08172290009697 28.368634384330456 27.4156315551657 28.406894469460987 27.694014678750683 28.405443641793237 27.89317845372291 27.786187709742823 27.557558099945894 28.197646438310734 27.075848507292616 28.11214967724247 28.31933210423861 28.547715291810288 27.559542278881235 27.590238837107982 28.06169895399289 27.986649440999628 27.550349472469982 28.240966437306188 192.0 165.0 151.0 173.0 181.0 251.0 210.0 224.0 229.0 250.0 217.0 231.0 266.0 236.0 172.0 237.0 377.0 299.0 196.0 172.0 245.0 236.0 222.0 241.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.0 NA NA NA NA NA NA NA NA -0.4968994250283494 0.004669131805023211 0.010994483948432015 GO:0006353 DNA-templated transcription, termination biological_process 24.034022901344663 25.62435343247055 24.81933670213256 25.369600051583102 25.240069298763512 24.927800359925545 23.095319649041553 25.99478351356367 22.124573739598212 25.612704553892414 23.470751009652343 25.84063987756702 24.536132044472108 25.955017505552878 23.891304845881034 25.57503957785177 23.159757704458546 25.523902232922488 24.734849897030465 25.70762892634503 24.03503502117962 25.09039671690948 22.40188899072141 26.29925033835964 23.495451179930626 24.87555459659542 26.0 33.0 21.0 27.0 15.0 56.0 15.0 52.0 26.0 45.0 25.0 42.0 25.0 44.0 24.0 50.0 40.0 47.0 20.0 32.0 17.0 50.0 25.0 43.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.5903305311258862 6.784570247173055e-05 0.0005498145239267514 GO:0006355 regulation of transcription, DNA-templated biological_process 26.033439031930524 27.56794452148754 26.57482374506132 27.20924822385836 26.71416751833899 26.99591226813231 25.10955271876924 27.891619910162216 25.16534061097537 27.93748802318273 25.823471207233286 27.726537668135386 26.14702420030795 27.32279878345085 25.608931410472703 27.576109288742558 24.98684983767446 27.55262591851593 26.871083011450573 28.033025549691626 26.35947765092229 27.179505877553424 25.276209130210663 27.35908253080883 26.11576716580459 27.623683132408853 85.0 110.0 77.0 108.0 80.0 150.0 77.0 147.0 109.0 132.0 111.0 137.0 92.0 132.0 77.0 137.0 176.0 152.0 96.0 99.0 74.0 141.0 110.0 144.0 4.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 5.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.5345054895570165 3.225641456243767e-05 0.0005099643033035255 GO:0006364 rRNA processing biological_process 24.52419747437078 25.728526470234517 24.95857354339549 25.22630494143984 24.463987845963093 25.233554634413533 23.49512580956151 25.88038220998467 24.68375653272217 25.372705938753864 24.888666057786626 25.74741884670287 24.894034482276158 26.25625478224929 25.184459145158677 26.035715152063073 22.99727454527789 25.80859315256764 24.496382516233677 25.67720728008132 24.46009537412305 25.37370882772982 24.380152905981213 26.30605036282679 24.076385658744712 25.22109819954114 51.0 68.0 46.0 77.0 34.0 78.0 29.0 72.0 54.0 82.0 57.0 72.0 51.0 95.0 28.0 90.0 53.0 62.0 51.0 63.0 33.0 93.0 54.0 67.0 4.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 4.0 4.0 3.0 3.0 3.0 3.0 4.0 3.0 -1.2043289958637367 3.225641456243767e-05 0.0005099643033035255 GO:0006396 RNA processing biological_process 26.05999201440291 27.040427850169483 25.988316808747463 26.545271005340123 25.966591518842677 26.985186134680234 25.44463170480282 27.099326787242408 26.059386663797607 26.71528919349041 26.425220203288298 26.914438038106127 26.551749245673776 27.54633518706799 26.265084311906786 27.168223340780845 24.991037060436078 27.07076898678362 26.347682704613728 27.10950145269407 25.80266884691111 26.613611945546285 26.13671330130262 27.62891027314362 26.093081639908533 26.608583768860587 121.0 186.0 118.0 209.0 112.0 218.0 117.0 202.0 177.0 231.0 168.0 191.0 122.0 264.0 84.0 262.0 194.0 211.0 122.0 182.0 123.0 264.0 152.0 200.0 4.0 4.0 4.0 3.0 5.0 4.0 3.0 5.0 4.0 5.0 5.0 4.0 2.0 5.0 3.0 5.0 5.0 4.0 2.0 3.0 3.0 5.0 4.0 5.0 -0.9804358357665741 4.146041132679973e-05 0.0005099643033035255 GO:0006399 tRNA metabolic process biological_process 28.583412734040238 29.167647270209603 27.860579147498303 28.6813607222605 27.91643429933936 29.313751518377853 28.40461918118763 29.047601271015953 29.172072574806066 28.6709093126202 29.10594081763948 29.189076325232445 28.88038713185372 29.11882453318313 28.80313542019693 29.57395221723648 28.12998186631202 29.00985179890038 28.70665400467384 29.421056685152017 27.91756930868664 29.0128320487118 28.59355210767639 29.61510604744653 28.708505074198193 29.005061402623372 313.0 396.0 323.0 501.0 511.0 563.0 625.0 570.0 663.0 591.0 649.0 444.0 615.0 597.0 439.0 614.0 769.0 681.0 413.0 532.0 615.0 612.0 596.0 606.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.5842345361693653 0.0032349119169146935 0.007931571851295751 GO:0006400 tRNA modification biological_process 22.57279894652552 24.869074785961022 23.45988350146756 24.61412720289134 22.89421006733377 25.204002093971624 22.163250364451905 25.07036435135264 21.93760408192965 24.34331160114501 23.06357696888967 24.220725653352666 22.56344775011245 24.626744889207693 22.115183360391764 24.96194182807171 21.666648226545547 24.952668580273237 23.00520010930018 25.195844440959142 21.948792867522265 24.571047423489148 22.32673385930183 25.652460805632376 22.576005847240072 24.26542976213036 16.0 52.0 23.0 60.0 20.0 65.0 19.0 48.0 38.0 48.0 31.0 41.0 14.0 68.0 13.0 64.0 42.0 52.0 15.0 57.0 16.0 70.0 20.0 44.0 5.0 6.0 3.0 6.0 4.0 6.0 3.0 6.0 6.0 5.0 4.0 6.0 5.0 6.0 3.0 6.0 6.0 6.0 3.0 6.0 3.0 6.0 3.0 5.0 -2.296275839435502 3.225641456243767e-05 0.0005099643033035255 GO:0006401 RNA catabolic process biological_process 24.870855925922605 24.85487758946693 23.78769520750573 24.394608524663855 23.22647862458941 25.199159991164308 24.839835202267622 24.720825510591602 25.183040594789663 23.764769802563766 25.389167731357503 24.750158117817502 25.395970308426524 25.280539267455286 24.783736935883088 25.05410019096601 24.28485867159323 24.761033980918242 25.490461782116665 24.7970468859685 24.33161977786045 23.942786464503694 25.024035812374397 25.968710927351303 25.100178282011434 24.137109644713398 34.0 48.0 14.0 66.0 50.0 49.0 57.0 35.0 61.0 66.0 53.0 55.0 52.0 68.0 34.0 71.0 88.0 61.0 29.0 33.0 63.0 72.0 53.0 43.0 2.0 3.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 1.0 2.0 2.0 2.0 2.0 0.01597833645567448 0.6033317722918665 0.6716842567531217 GO:0006402 mRNA catabolic process biological_process 24.665998016701163 23.05627667397799 22.702874151213194 22.15861552528296 23.02786457203418 23.86623806436061 24.499479522913138 22.210612071537465 25.10588233113545 22.17041250410251 25.23583003342503 22.99947147698755 25.27436311545557 23.1691555127458 24.676411153932065 23.371516694374204 23.70902530720624 23.034382907973967 25.31474694813983 23.518698363053108 24.23515902250396 22.22180099900193 24.93181803697368 23.765412881914912 24.844298756572837 22.673697013526755 14.0 7.0 7.0 23.0 38.0 10.0 52.0 11.0 45.0 28.0 39.0 8.0 40.0 21.0 25.0 23.0 72.0 25.0 25.0 8.0 52.0 22.0 41.0 16.0 1.0 1.0 NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA 1.0 1.0 NA NA NA NA NA NA 1.609721342723173 0.0009986863791802587 0.0031633517797384847 GO:0006412 translation biological_process 30.88420661366301 30.18493151690301 29.949738425925652 29.46559945242517 29.543439689922234 30.189773237602 30.378184170187765 30.17685085867581 31.06026772848164 29.78242167095573 31.04439735365448 30.452597139010035 31.009565693546786 30.13424233916492 31.29310104248341 30.44042118744543 30.492798635467967 29.93217792405049 31.6242211646444 30.550270727325987 30.67834516869741 29.98190211853517 31.47141163816415 30.457081026133032 30.748436036742497 30.28445881510372 472.0 214.0 264.0 481.0 485.0 374.0 715.0 378.0 640.0 465.0 577.0 272.0 851.0 362.0 518.0 331.0 747.0 649.0 546.0 250.0 689.0 329.0 519.0 430.0 NA NA 2.0 1.0 1.0 NA 2.0 NA 2.0 NA 2.0 NA 2.0 NA 2.0 NA 1.0 2.0 NA NA 1.0 1.0 2.0 NA 0.699275096760001 0.006656727227605034 0.01478219854101616 GO:0006414 translational elongation biological_process 24.503702158127346 24.10815221431806 24.405424474278444 NA 13.618575139861846 16.924458936006953 25.18831300359457 24.429760165528464 25.100797440417146 25.308008040795045 19.90492455097895 25.21949878624359 24.94206681580937 23.75989233826765 20.751825380977408 23.080444244271412 25.30175956034833 24.34799142178377 25.07847189723709 24.720518630484968 23.87806035043211 23.79920158665989 25.21212609005189 19.96067541402171 24.451516624231076 22.91206909240305 2.0 NA 1.0 1.0 4.0 2.0 4.0 2.0 5.0 2.0 3.0 4.0 3.0 3.0 1.0 2.0 7.0 3.0 3.0 3.0 3.0 3.0 6.0 5.0 1.0 NA 1.0 1.0 3.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 1.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 0.39554994380928576 0.42365593666732415 0.5069248408061559 GO:0006415 translational termination biological_process 25.367692438038787 25.649274461384906 25.23842285771953 25.580868924924594 25.09440896262424 24.433442187173267 25.469193906694702 26.13431044462201 25.125110263112425 25.46924442096678 25.52390939331046 25.645575018709675 25.62704423188634 26.140706819410052 25.44087259207157 25.593060424958487 25.115091110105823 25.37123598529094 25.065832035402387 25.764607531769794 25.621492300117463 25.066274873566122 25.3139167344134 26.25214522500581 25.59478465694244 25.4552572175162 24.0 17.0 30.0 29.0 28.0 29.0 26.0 25.0 24.0 27.0 29.0 30.0 34.0 35.0 29.0 26.0 31.0 32.0 29.0 33.0 33.0 27.0 32.0 39.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.28158202334611815 0.10596880912720232 0.15148805703407617 GO:0006417 regulation of translation biological_process 27.623388551982885 27.95432011918929 27.719154934894398 27.55336509387248 27.65405440463396 28.187211482910968 27.36970435925057 28.233524742598345 27.441885883242417 27.89650555196897 27.532498177196665 28.0774552700655 27.54439403994711 27.88128675628786 27.72735755741179 27.83812880933517 27.232911638977928 27.804329089877964 28.048965987617397 28.24571692534078 27.725387039857672 27.81638816273253 27.650227093704828 27.750025476279287 27.66734565274923 27.99554979280959 68.0 56.0 64.0 77.0 67.0 85.0 79.0 82.0 86.0 95.0 79.0 63.0 78.0 88.0 63.0 84.0 108.0 94.0 82.0 64.0 74.0 77.0 78.0 93.0 2.0 4.0 4.0 2.0 5.0 2.0 5.0 2.0 5.0 4.0 5.0 4.0 2.0 2.0 4.0 2.0 6.0 2.0 3.0 3.0 5.0 3.0 3.0 3.0 -0.33093156720640593 0.0008121171348941295 0.002709952364566507 GO:0006418 tRNA aminoacylation for protein translation biological_process 28.428556555233964 28.93084430001965 27.62111015857245 28.45161837570244 27.752959169896393 29.05939730725564 28.25700970697805 28.783029394976808 29.034108334250774 28.434613085444468 28.938077683194656 28.97113357839273 28.740666430211807 28.90141143746509 28.690948133065795 29.33895839215861 28.01761989936925 28.711888400999985 28.505609305604143 29.18564777511131 27.745423557359878 28.79022521256572 28.43382812390521 29.368683249010125 28.55955485003589 28.824173468652692 273.0 312.0 275.0 400.0 454.0 456.0 553.0 480.0 571.0 490.0 576.0 371.0 559.0 482.0 395.0 498.0 671.0 582.0 357.0 439.0 548.0 484.0 531.0 515.0 20.0 19.0 18.0 19.0 20.0 20.0 20.0 20.0 20.0 20.0 20.0 20.0 20.0 19.0 20.0 20.0 20.0 20.0 20.0 20.0 20.0 20.0 20.0 20.0 -0.5022877447856864 0.005583616806378765 0.012692811975156102 GO:0006419 alanyl-tRNA aminoacylation biological_process 24.518364115180212 25.918026044816948 25.50998793371345 25.797836618897637 25.179499688202554 26.312229896983943 23.66165057513515 25.19651036830664 24.384274351855783 24.95274869541241 24.655553388063588 26.524008032935292 24.496317882647556 26.36980531458005 24.473772152057446 25.82496793937822 23.967846520459922 24.588693834898038 24.71329282554939 26.229347227920538 24.04862818540593 26.228286198007392 23.160712115309373 26.206637248096037 24.478701005902533 25.443315460732308 29.0 28.0 24.0 38.0 18.0 31.0 32.0 28.0 33.0 27.0 28.0 27.0 27.0 31.0 22.0 30.0 40.0 39.0 19.0 31.0 16.0 30.0 32.0 29.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.3996619296367356 0.00021985068263840352 0.0009941074345388681 GO:0006420 arginyl-tRNA aminoacylation biological_process 24.612693512840114 24.710693147936148 23.26444208906641 23.949833577697344 23.364214067302818 24.988928579512237 24.525956638020137 24.486013309497928 25.68595500982861 24.230147170849897 25.29370262748013 25.084687849547855 24.75044305479056 24.348242211551884 24.27582156565164 25.006807593024718 23.771431364974948 25.062425279065447 24.450913560677805 24.978023667897162 24.615556861684023 24.352713095304583 24.64543706903968 24.321924444770413 24.837082217343106 25.088465612398647 25.0 27.0 21.0 26.0 50.0 38.0 56.0 49.0 59.0 43.0 55.0 30.0 54.0 37.0 32.0 37.0 56.0 40.0 37.0 37.0 50.0 31.0 49.0 58.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.09799963509603415 0.5253727863737021 0.6008633207515945 GO:0006421 asparaginyl-tRNA aminoacylation biological_process 24.74849640045705 24.613214040029483 23.88842187591555 24.01147907622848 24.39204717477371 25.007725299786678 24.802551971533145 24.342211771137148 25.19633644360383 23.955498034504146 25.045726712641386 25.179854298757352 24.83805187809363 23.815206559949555 24.86091044470284 25.222955715620536 24.428808972444664 24.65157784685893 24.66818827240758 25.221420462884485 24.39339593073707 24.410184345783573 25.121873481455538 24.441844658248172 24.84294681047493 24.043354785072108 21.0 14.0 21.0 24.0 35.0 18.0 33.0 16.0 36.0 28.0 34.0 12.0 44.0 24.0 29.0 25.0 32.0 34.0 25.0 26.0 35.0 22.0 37.0 21.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.13528236042756703 0.4529203011037244 0.5347630423627702 GO:0006422 aspartyl-tRNA aminoacylation biological_process 24.713107728711897 25.002425189823352 23.17192379012657 23.979929573848644 23.47089944411405 24.33185556613036 24.402249594032607 25.212326778890628 24.970915073009557 24.736447062805556 25.276589371647052 24.91161367898929 25.377167637471754 24.876812264917465 24.215502381000015 25.155379448886183 24.628925989045843 25.214999507122844 24.685293729485263 25.278306438381552 24.95847941219701 24.86707096224205 24.91724760016895 25.710820977104486 24.975635619064608 25.0165813631886 20.0 21.0 24.0 33.0 33.0 38.0 47.0 41.0 51.0 46.0 52.0 35.0 41.0 43.0 35.0 43.0 51.0 49.0 37.0 38.0 50.0 46.0 46.0 41.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.2893174611114553 0.24821307898992373 0.31935043564889154 GO:0006423 cysteinyl-tRNA aminoacylation biological_process 22.194371246447506 20.756368531704165 20.228509398465004 19.942992560694986 20.5862098402954 20.91997906002905 22.26334948153843 21.31970190146822 21.753701057905907 21.235175411136986 23.370179950772012 20.176815891911087 23.614192796469634 19.947915518925804 22.56143060802591 21.14556129380813 21.6058710252884 20.904383910357947 21.80752371807549 20.815582086095024 21.19885197580754 20.604432505300387 21.683938108843797 21.353192782154586 21.82177591718992 19.145501436881045 5.0 4.0 8.0 4.0 9.0 7.0 9.0 7.0 16.0 6.0 13.0 5.0 5.0 7.0 7.0 7.0 11.0 6.0 11.0 6.0 11.0 7.0 8.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.438002714743341 0.0022136919545913893 0.006045268182341475 GO:0006424 glutamyl-tRNA aminoacylation biological_process 24.52687607925229 25.483226241941324 22.985456689524003 25.395708951126622 24.600898191988737 25.392155674322954 24.340458051852703 25.17749191218157 25.013830073589443 24.73468349883776 24.89201035418704 25.544328762951608 25.236231616207505 25.52002584239129 24.333772365668807 25.66107690403539 23.78489605071621 25.022524153393807 24.52959633884953 25.564394299894207 24.25411186065405 25.78690977625915 24.548351941736325 26.22593356198709 24.64218368632929 25.20287610186202 22.0 16.0 21.0 26.0 34.0 32.0 37.0 39.0 49.0 38.0 51.0 29.0 43.0 31.0 31.0 31.0 52.0 43.0 35.0 30.0 48.0 32.0 48.0 44.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9563501626890343 0.0001386794054294884 0.0007006959432226783 GO:0006425 glutaminyl-tRNA aminoacylation biological_process 21.283570841669405 20.417775674400648 18.666247761473237 NA NA NA 21.146952597450298 13.595834209388432 18.923756781297282 21.364217915766076 21.762120757911358 21.39437862085678 21.78785411960189 20.623187579595076 20.61539312456152 NA 19.74298822867097 19.198282469978352 22.57067907747731 20.749314251632175 21.178555033599764 16.236168152934756 21.934566456781678 18.959344961918163 21.29410148156536 21.29467211924024 2.0 NA NA NA 8.0 1.0 3.0 10.0 7.0 6.0 8.0 3.0 7.0 NA 5.0 1.0 16.0 5.0 5.0 1.0 8.0 3.0 8.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.8657951672687574 0.20999967175560952 0.2779210926309657 GO:0006426 glycyl-tRNA aminoacylation biological_process 24.29370653825772 22.88322053554639 19.380827142101623 22.010290705975923 18.03672663817661 21.187134921053485 24.31635871289061 22.290659448763293 25.882771205028742 22.531230479758808 25.28776902029002 22.502986846848785 23.839261717432446 22.41780240038818 24.414927584697708 22.85966172490425 23.57860297316645 22.53463416179077 24.23116274929191 24.51528657282681 23.14404668705063 20.92271503008153 24.103924082534828 23.976417021942893 24.587577058345666 22.804622017510773 5.0 7.0 2.0 8.0 27.0 9.0 41.0 7.0 34.0 11.0 26.0 9.0 32.0 7.0 15.0 8.0 43.0 26.0 5.0 7.0 33.0 13.0 26.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.4104860027113304 0.02824036873330045 0.04901805310036017 GO:0006427 histidyl-tRNA aminoacylation biological_process 23.950547190263357 24.732670957408377 23.861239840303355 24.419781860535288 24.7407115238836 25.231953583037306 23.623398571017823 24.25471663455307 23.31579814114098 24.09419527408471 23.625622639836322 23.856303249679236 24.486419368322483 25.23912063396451 24.61197353924048 25.205468447924968 23.280769555616132 23.687081294562287 23.444864725976053 25.465367908992754 24.111416431529065 24.77519394838603 23.475324994803838 24.890232164553556 23.78167884391391 24.367704813091674 10.0 12.0 14.0 14.0 15.0 15.0 12.0 18.0 16.0 21.0 19.0 14.0 18.0 19.0 14.0 22.0 19.0 21.0 18.0 16.0 14.0 24.0 17.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7821237671450199 0.005583616806378765 0.012692811975156102 GO:0006428 isoleucyl-tRNA aminoacylation biological_process 24.941282221493825 25.91666154458588 23.660870140934215 25.91361144304284 24.16412661502091 26.60572761817173 24.757714845287104 25.91762753780645 25.945684527938546 25.16871671770891 25.388069089839355 25.3729397026473 25.156477811512648 25.963367328929728 25.584028799263464 26.248207047124076 24.11516698146781 24.75014292022133 24.439621166437373 25.97374692428605 23.531278745131264 25.72626900271081 25.331693357930927 26.56124481050502 25.046414130589305 25.75012057420733 20.0 37.0 26.0 51.0 39.0 50.0 51.0 48.0 38.0 42.0 46.0 33.0 51.0 50.0 24.0 53.0 50.0 45.0 28.0 45.0 56.0 44.0 39.0 60.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9753793230920564 0.0018227351663913985 0.005134928866041682 GO:0006429 leucyl-tRNA aminoacylation biological_process 23.42424993332272 24.01808340276193 22.32665526963274 22.882804132120146 20.760143389501046 23.06935033495667 22.822843235475148 23.737083334694468 23.600268133866305 23.22617005994089 23.931772066835407 24.032323097609833 23.11525959839496 23.73962626256257 25.17954926404973 25.950639932059993 22.11444662529852 23.14784632206677 23.560046105397447 23.22752248506089 22.90746811584281 23.155086827858852 22.93081327306653 24.71451642718848 23.52179499205153 23.459327664190425 7.0 10.0 6.0 11.0 14.0 16.0 21.0 10.0 22.0 11.0 16.0 14.0 13.0 16.0 13.0 12.0 25.0 16.0 9.0 10.0 16.0 18.0 21.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5938334694392111 0.11903289845700783 0.16804644488048165 GO:0006430 lysyl-tRNA aminoacylation biological_process 25.29584271709529 25.21236416540565 24.233376877508977 24.139732918491678 24.15876347317252 24.7994097991364 25.039384074081287 25.474740210249767 25.75046166325339 25.39164136343692 25.97367853258667 25.100600686175103 25.638708928567446 24.053736242612533 25.55885154140468 25.455019294621916 25.63238029056224 25.89378201269929 25.3901089521147 25.17589150317984 24.30976750543863 24.908515652892326 25.28401863092561 25.296900266312186 25.242984143395162 25.734366986960698 25.0 22.0 27.0 26.0 36.0 46.0 42.0 38.0 47.0 42.0 47.0 29.0 55.0 48.0 40.0 41.0 47.0 45.0 37.0 43.0 45.0 36.0 39.0 40.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.08347855168964102 0.5637028616507731 0.6360770084449954 GO:0006431 methionyl-tRNA aminoacylation biological_process 23.49323642512893 24.189752199051 23.066731798603396 23.808309156876 23.029915404837237 24.185802284615704 23.08277852736835 23.986960733416552 23.837871058899626 23.989012922159503 24.083004143669967 24.06582652837078 24.208818775473482 23.36029647212616 23.915098966268463 24.73507236095523 23.128808221010104 24.48384915639576 23.386699241690717 24.80652236444239 22.25256765395369 23.603161915529533 22.700484538162087 23.913367445778853 23.888949567092318 24.5740138632504 13.0 15.0 18.0 18.0 16.0 23.0 21.0 25.0 21.0 26.0 28.0 18.0 24.0 28.0 17.0 29.0 35.0 29.0 12.0 27.0 19.0 31.0 23.0 37.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6965157739220693 0.007911788680711459 0.016907384030013527 GO:0006432 phenylalanyl-tRNA aminoacylation biological_process 23.94771974532488 25.001139551948608 21.89883330903761 24.0887051735188 22.04770025664668 24.604399267149105 24.297433382192068 24.755426885090102 24.828401620451412 24.49994602781528 24.2859229658003 24.932926316316344 24.534911192053798 24.70212225969009 23.992851062087478 25.428348328976487 23.510595366184287 25.1681450870871 24.410128451512023 25.470136598641513 21.97716501176545 24.533242663385593 23.858263130379683 25.84644524186585 24.286950553065253 25.031727990970698 9.0 26.0 10.0 39.0 23.0 30.0 24.0 36.0 25.0 36.0 33.0 25.0 25.0 36.0 19.0 37.0 38.0 47.0 15.0 35.0 29.0 39.0 26.0 32.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0534198066237295 0.0006583371695572323 0.0022696264851033866 GO:0006433 prolyl-tRNA aminoacylation biological_process 23.29771794955893 24.47343895753479 23.499898148153143 24.063903823831215 23.484355800411734 24.61206886579595 22.346617883188248 24.92009064365202 23.72772987003844 24.225456522889747 23.501035981011572 24.72562543746325 23.527040850657805 24.87154676407733 23.176779312887625 24.6981208536964 22.359839076685724 24.30119182891077 24.150486184534802 24.01049587842571 20.490467924907023 23.75127017140579 23.45857382634705 24.80931449084823 23.31916367803284 24.120019614155183 21.0 15.0 15.0 18.0 17.0 24.0 21.0 27.0 17.0 26.0 21.0 22.0 22.0 23.0 15.0 29.0 36.0 29.0 8.0 19.0 22.0 25.0 19.0 24.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1757210079758593 8.637667594722788e-05 0.0006159890947550879 GO:0006434 seryl-tRNA aminoacylation biological_process 24.614210745859285 25.228817417231216 23.91453971470353 24.30439609217024 22.781599512754678 25.637167177683807 24.6224370903254 25.123661626614517 25.49374626999957 24.67227075413209 25.40139931397837 25.340136861038342 24.5661737293901 25.16759045821596 24.58713472497571 25.567084367793807 23.81591564295579 25.167114561516897 25.113524667029928 25.534918707080287 23.31808473867123 25.033268029828385 24.769478453324947 25.669597754221744 24.71753664946463 24.92184171466917 10.0 15.0 11.0 19.0 19.0 20.0 35.0 21.0 29.0 22.0 15.0 14.0 28.0 23.0 19.0 23.0 25.0 30.0 16.0 20.0 26.0 26.0 19.0 29.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6146066713719307 0.009374768459434895 0.01937038251220985 GO:0006435 threonyl-tRNA aminoacylation biological_process 23.561754022692504 22.10782297820421 19.416492852232274 15.758360393357394 19.467372072185334 18.81120125550494 23.037868476718913 21.32934393246065 24.432367688475708 22.186910257883373 23.84243284113253 20.3145524447099 23.589661459226022 21.545084273027754 24.588296770838127 23.431286573140106 23.832383915692574 22.787308421778835 23.962388939821874 22.757843102345234 21.467799985564767 21.55807459229031 23.95317939248348 22.021904991832393 23.58638985153048 23.095040710654654 4.0 1.0 2.0 2.0 10.0 5.0 15.0 5.0 14.0 7.0 19.0 3.0 22.0 7.0 13.0 5.0 25.0 16.0 9.0 5.0 23.0 5.0 13.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.453931044488293 0.01531382171343201 0.02967647437634029 GO:0006436 tryptophanyl-tRNA aminoacylation biological_process 21.62466686232405 21.487930283878175 19.166298707702246 20.611814537137533 NA 21.09761602275949 21.04083810397725 21.153110979255267 21.259882088464924 21.72273313391219 22.260844351724852 21.916538364072718 23.034673594916896 21.531459218879306 20.68033245781926 21.132520711496237 21.024036525758408 21.658466959356552 22.090047423802186 21.701202672427453 21.328761384172548 20.095732674290364 21.635904910526524 22.701316405049113 21.267109673919023 20.70148967372511 3.0 5.0 NA 2.0 7.0 10.0 9.0 10.0 9.0 10.0 9.0 9.0 5.0 6.0 6.0 10.0 9.0 8.0 6.0 5.0 6.0 6.0 6.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.13673657844587694 0.950924583799356 0.9577970205788449 GO:0006437 tyrosyl-tRNA aminoacylation biological_process 22.93576058235476 23.130879420663508 22.581440932405272 22.841381762096447 22.73426249150721 23.11814779326808 22.108215232493357 23.9546835110585 23.399504400382266 22.52403605585898 23.72117290705639 23.08827162688961 22.68342200745209 23.983898749195586 23.95855729762097 23.045780930884035 22.146668100362096 22.356696514077843 23.042755537509127 22.717213192706442 21.649691405746626 23.19397191494328 22.205620664060262 23.481377989195682 23.12724137679995 21.768230300436088 8.0 9.0 8.0 14.0 10.0 11.0 16.0 15.0 15.0 12.0 12.0 13.0 20.0 15.0 8.0 14.0 22.0 13.0 9.0 16.0 10.0 14.0 14.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.19511883830874766 0.3556110610952391 0.43337630976650365 GO:0006438 valyl-tRNA aminoacylation biological_process 23.90450055273272 24.576958558125078 23.46086073395765 24.093937369208522 23.19093606031765 24.620723742426662 24.47274532406628 23.84538682459009 23.96225976933784 24.00480467553601 24.094990619028817 24.25349827739287 24.342740078196865 24.62313189958289 23.80943323612957 25.41879915368918 23.654884779410033 24.42943348908899 23.844867460573177 24.46561913873123 22.090348642753096 24.59775015476627 24.15630927715468 25.186875291443076 24.41375671184361 24.55609195171497 14.0 28.0 17.0 27.0 34.0 31.0 28.0 30.0 33.0 30.0 44.0 27.0 23.0 31.0 30.0 41.0 39.0 41.0 16.0 22.0 30.0 31.0 41.0 34.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6724580053923574 0.0032349119169146935 0.007931571851295751 GO:0006449 regulation of translational termination biological_process 21.07515959165531 23.24457276888099 22.338503526065324 22.88498836717773 22.275962749492408 23.23527510379333 19.295430370430385 22.711253158905638 19.084144233145995 22.86402430453281 19.472778049629785 23.034036420152574 20.67168237622478 23.101712236994466 20.41948368563009 23.80734430320005 20.087801552482297 23.397620514952386 21.63760749558443 23.32748930621928 21.271369264921912 22.683819323065034 19.88408358259384 23.899041593054072 21.633946851066312 23.379224081112863 14.0 16.0 15.0 18.0 4.0 18.0 4.0 17.0 5.0 19.0 8.0 18.0 10.0 28.0 5.0 27.0 10.0 22.0 14.0 20.0 5.0 23.0 11.0 25.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.169413177225678 3.225641456243767e-05 0.0005099643033035255 GO:0006457 protein folding biological_process 28.95203607402452 30.32999277526034 28.75572271283248 29.622302717691827 28.114326514561977 29.566974295876175 28.76080468034689 30.55677942349689 28.094330911307697 30.658690768705444 28.63469339166237 30.249812483317648 29.031192318058128 30.140278083163942 28.65771416616927 30.454340131735893 28.62845332755728 30.27538229713161 30.61268439174895 30.783663138815125 28.7601292914368 30.138410739015928 28.58986190978849 30.138744287222572 28.720103084826988 30.790193509595266 201.0 151.0 181.0 222.0 216.0 250.0 256.0 263.0 236.0 259.0 260.0 195.0 283.0 240.0 214.0 235.0 356.0 352.0 231.0 257.0 240.0 234.0 234.0 323.0 2.0 2.0 2.0 1.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 -1.3779567012358207 0.0002755038114342687 0.0011655212090507369 GO:0006464 cellular protein modification process biological_process 23.861355264413977 24.930567515323208 23.820294832233714 24.84954174769123 25.297634151437588 25.851050223188683 23.06551030328176 24.62374194918574 23.726773897431368 24.759831600269518 23.05040975289162 24.188552199589022 24.244817358532586 25.173225363279304 22.3229033776365 25.07401173459917 21.438170427351906 24.375437144683445 23.95917417533427 24.94516936346043 24.55830222143092 24.65262460238681 23.866270613033038 25.21483088111888 23.41734223289357 24.689506459553648 39.0 38.0 40.0 48.0 33.0 58.0 26.0 59.0 40.0 55.0 52.0 51.0 30.0 53.0 15.0 47.0 59.0 63.0 42.0 51.0 36.0 33.0 44.0 55.0 5.0 5.0 4.0 4.0 7.0 6.0 9.0 6.0 7.0 8.0 9.0 7.0 5.0 6.0 5.0 6.0 9.0 7.0 6.0 4.0 8.0 6.0 7.0 5.0 -1.0692122509092314 0.0008121171348941295 0.002709952364566507 GO:0006470 protein dephosphorylation biological_process 22.45116688339358 22.869395908922467 22.24240021452139 24.078371561957287 24.147484158379974 16.427723962664167 22.047488185363694 23.41492641583398 23.147325211067123 22.824225997983266 19.668455124867968 22.544605869755074 22.55225429814681 22.977129758287944 20.25026650024588 19.31513358264958 21.12810595029858 21.016022304068965 21.923327567166638 23.96797373520289 23.02632905163079 22.90347594471773 21.948201558008147 19.25515695355895 22.117838959549008 23.68760156659452 14.0 12.0 16.0 1.0 12.0 24.0 10.0 24.0 6.0 10.0 14.0 12.0 10.0 3.0 8.0 10.0 16.0 19.0 21.0 19.0 11.0 2.0 15.0 20.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.41822902552888763 0.6033317722918665 0.6716842567531217 GO:0006508 proteolysis biological_process 24.69214967927356 22.841771229606238 18.059705850063974 NA 21.38214967883007 19.08812422341253 25.097938174432944 22.826673431783615 24.87854299734521 23.376113044805752 25.178648346379628 22.807000708293923 25.146312993432158 21.428351876761702 24.686132596774073 21.334663231037734 24.55700864293873 23.53365202176729 25.702592265541877 23.79525689747475 22.8905379985524 20.330218606360663 24.146107584321733 21.906547381767005 25.50988372802508 24.183361794801026 1.0 NA 14.0 4.0 39.0 15.0 54.0 36.0 45.0 25.0 63.0 11.0 42.0 12.0 37.0 23.0 78.0 38.0 24.0 9.0 42.0 12.0 47.0 41.0 1.0 NA 1.0 NA 2.0 1.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 1.0 2.0 1.0 3.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 1.8503784496673212 0.009740122405271898 0.020058865943530246 GO:0006515 protein quality control for misfolded or incompletely synthesized proteins biological_process 23.15392057295197 20.026832683367328 18.059705850063974 NA 17.72789785715386 NA 23.104199177402034 15.630534966084895 23.825233827457925 19.785149225957145 23.56258213341184 20.48262290086885 23.766167072166308 18.119534580875133 22.82179842810725 16.366763952322493 22.59236485187344 19.091198541015167 24.451352673561434 21.076993925426205 22.45778393563581 16.198123492391108 23.073589998305525 20.546774580268615 23.21025105903825 21.745653540077466 1.0 NA 1.0 NA 17.0 1.0 25.0 7.0 23.0 10.0 28.0 1.0 16.0 1.0 15.0 4.0 42.0 15.0 13.0 1.0 23.0 5.0 22.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.1270878895846437 0.0024201512716478463 0.0065802805817353205 GO:0006518 peptide metabolic process biological_process 30.89985028752289 30.278630526111172 29.97328332212586 29.629880253239694 29.59521822291159 30.231018758999664 30.402518106570916 30.36542026346228 31.07332012688581 29.91077447827621 31.05807579244699 30.484849507337195 31.02274418112165 30.260017707545284 31.307351975936562 30.494205836351558 30.521274732583503 30.031454678375827 31.63177334034901 30.64574030873089 30.68602777074157 30.08095400029938 31.475510349596853 30.55440998560305 30.77800144019765 30.336284365158768 502.0 260.0 294.0 513.0 520.0 415.0 744.0 420.0 667.0 502.0 604.0 310.0 884.0 401.0 555.0 377.0 784.0 703.0 578.0 285.0 713.0 366.0 561.0 466.0 4.0 4.0 3.0 3.0 5.0 4.0 4.0 4.0 4.0 4.0 3.0 3.0 4.0 4.0 5.0 4.0 5.0 4.0 4.0 3.0 4.0 4.0 5.0 3.0 0.6212197614117194 0.011074437676156606 0.022291771322328135 GO:0006520 cellular amino acid metabolic process biological_process 32.111588138352204 31.923010231865398 31.57323344575209 31.069672559883127 31.379795385586267 31.655170514389162 31.940392315424447 31.72123072103915 32.15741646860706 31.599859049260512 32.490293651527466 32.301679025941446 32.3599127987882 31.65849097818699 32.41486477216762 32.28812420180364 31.66802300108082 32.28836181983334 32.305760355811515 32.199267295134256 31.61943959324879 31.64602794422241 32.50422154926454 32.32196119960657 32.33046343059518 31.744190877243422 1933.0 2219.0 2301.0 3001.0 2329.0 3637.0 2686.0 3594.0 3219.0 3784.0 3412.0 2871.0 3244.0 3832.0 2219.0 4121.0 3783.0 3861.0 2901.0 3132.0 3269.0 3670.0 2920.0 3666.0 9.0 8.0 8.0 8.0 9.0 8.0 9.0 8.0 9.0 8.0 9.0 8.0 9.0 8.0 9.0 8.0 9.0 8.0 8.0 8.0 9.0 8.0 9.0 8.0 0.18857790648680606 0.2040238704744366 0.2705863871967023 GO:0006522 alanine metabolic process biological_process 21.135464135658697 21.52007376280237 22.291686539866767 20.823307156455027 20.16352319172333 20.211636587298386 21.54051119358411 21.72456443656785 21.261584584738046 22.252526847052998 22.301369099170717 22.46794168331253 21.355932878776585 21.580853931858922 19.12306832312999 20.04825893991933 21.354615956320924 18.28604540682558 19.693305187426237 21.97681686321895 19.484260899587355 20.028087305192408 19.31652436961346 21.697855781063577 21.213228119837847 22.421244603513976 11.0 5.0 3.0 3.0 6.0 7.0 12.0 11.0 17.0 14.0 9.0 11.0 3.0 9.0 12.0 3.0 6.0 14.0 3.0 6.0 3.0 8.0 6.0 14.0 4.0 4.0 2.0 2.0 2.0 4.0 2.0 4.0 4.0 4.0 2.0 4.0 2.0 2.0 2.0 2.0 2.0 4.0 2.0 2.0 2.0 4.0 2.0 4.0 -0.3846096271436714 0.24821307898992373 0.31935043564889154 GO:0006525 arginine metabolic process biological_process 27.08006476333575 26.35752643764627 28.256415899241425 25.60473707564593 27.75472128611576 26.305365359032386 26.321353095254 26.63008364333773 26.271001288350764 26.16103466106243 27.004778371952096 27.24773522760455 27.359145632632874 26.472644709991307 27.37386643572433 26.204927043893857 26.091189562656986 26.314498519617324 27.050025608183805 25.98267524637097 27.304821563147893 27.063274167900854 25.52760901072596 25.334435647887826 26.344895393916488 25.759046923385863 33.0 36.0 26.0 36.0 37.0 94.0 48.0 57.0 47.0 57.0 40.0 54.0 61.0 62.0 32.0 81.0 52.0 45.0 25.0 47.0 30.0 55.0 38.0 46.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.7225383256894773 0.043308142810791976 0.0706517153305469 GO:0006526 arginine biosynthetic process biological_process 24.30964038858137 24.16067686891587 22.40219284442372 21.994704648111483 17.120252778895008 21.643602415252087 24.689618841003647 24.214095247203346 23.264119538681502 24.274738158121448 24.44262870812645 24.75267934071267 25.25752721859581 24.174705625125483 24.865228080352157 24.91394917753261 24.702442490203968 24.666416488208288 24.066506515576123 23.35592943248432 24.09791180500121 22.7462144719496 23.91927620543735 25.15735944126828 25.041804953222734 24.03549718433113 6.0 21.0 2.0 12.0 17.0 53.0 15.0 37.0 15.0 34.0 24.0 38.0 29.0 46.0 19.0 54.0 16.0 27.0 8.0 26.0 12.0 47.0 19.0 25.0 NA NA NA NA 1.0 1.0 NA NA 1.0 1.0 1.0 NA NA NA NA 1.0 1.0 NA 1.0 NA 1.0 NA 1.0 1.0 0.14896351966550014 0.7290344895388041 0.7743276961229171 GO:0006527 arginine catabolic process biological_process 26.011970025523855 25.42458836077368 27.344752049954963 24.48053137690885 26.8623887946802 25.95854492174891 24.847505221703052 25.75321403895604 25.37392281706285 25.182111302212192 25.69493158965287 26.23078456632494 25.244629556647958 24.894692276854762 26.445789130932976 25.23452411608283 24.978307007204165 25.497746610484533 26.30639432704136 25.00110616194653 26.5050452908787 26.600904348852747 23.447359775838965 21.63889939301935 25.1677819479028 24.375644955917654 11.0 5.0 9.0 14.0 11.0 12.0 10.0 8.0 14.0 10.0 6.0 7.0 12.0 9.0 5.0 15.0 17.0 7.0 8.0 12.0 10.0 6.0 11.0 8.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 1.0 2.0 2.0 1.0 2.0 1.0 0.5873816647501755 0.24821307898992373 0.31935043564889154 GO:0006528 asparagine metabolic process biological_process 24.46387154035343 24.51787178867021 21.638613760859084 22.333005801971094 20.08951189492431 24.295694924279534 23.359944641075874 23.567430939384607 23.06922728311915 22.83743291827079 24.371087337606397 23.712995948753644 24.00709817257141 21.415968852874574 23.265350149085695 25.94244823463009 23.31948858434061 25.74792844397909 26.65672480181147 22.85838831258288 25.64611560680673 24.22181565527814 23.92274235599564 25.918442858161374 24.282814142477797 23.788675342833038 12.0 18.0 6.0 28.0 20.0 25.0 22.0 24.0 23.0 23.0 27.0 12.0 19.0 31.0 15.0 43.0 17.0 22.0 16.0 22.0 23.0 36.0 27.0 32.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.054000248316778965 0.8624902301359216 0.8917877441670506 GO:0006536 glutamate metabolic process biological_process 27.895700209987396 25.403409614555983 26.645020203421826 25.365290937927675 27.2745840467802 25.42408130279551 27.57591445932709 25.58478652310503 28.200055998233854 24.50661162634816 28.288459219902386 25.922985897280512 27.986535034622825 24.47717517711781 28.145372837079744 22.72222727360119 27.26672776686707 20.83814689283105 27.994580487288875 27.450947498010077 26.09349314848707 25.666036974743534 28.91729757046647 19.42571554036329 28.26555303424251 25.140067140980644 28.0 23.0 97.0 62.0 59.0 36.0 102.0 25.0 105.0 30.0 98.0 26.0 97.0 16.0 60.0 12.0 93.0 84.0 83.0 29.0 97.0 4.0 83.0 32.0 4.0 3.0 4.0 4.0 3.0 4.0 5.0 2.0 5.0 3.0 5.0 5.0 2.0 2.0 2.0 4.0 4.0 3.0 4.0 4.0 5.0 2.0 2.0 3.0 2.492290595431413 8.637667594722788e-05 0.0006159890947550879 GO:0006542 glutamine biosynthetic process biological_process 22.40484668618409 25.20547269370139 22.9509924798874 23.805516141278982 21.81484263316546 25.558983083592555 22.022316160378583 25.164562169781064 19.93171606098784 25.205883935380417 20.44091786129031 24.591397597757712 22.115583281021046 24.28145560217501 22.623447005558237 25.51472478680677 21.141626245571675 25.92031083668076 23.91977559305865 23.95555102546945 23.429218260806604 24.974369974166002 22.36334724578059 26.414912689072555 21.11803963083531 24.742285574813014 11.0 14.0 12.0 20.0 5.0 19.0 5.0 18.0 4.0 18.0 8.0 9.0 9.0 24.0 4.0 25.0 15.0 14.0 16.0 23.0 11.0 28.0 8.0 20.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.8006260075173017 4.146041132679973e-05 0.0005099643033035255 GO:0006544 glycine metabolic process biological_process 24.88451957384861 24.806278206420874 24.737402002821852 24.71201368685081 25.69885709500853 24.71243398336048 24.421214892434936 24.25319770545342 23.025512293206514 24.65463478117548 24.75185080609693 25.275963874049097 24.57198452320351 25.251474344659623 24.29911973152545 24.54290321891461 22.83351201854952 23.96273175092772 26.321657221203285 25.570812048924218 25.318650221001995 24.531684253652987 24.951722727288235 24.376106488648844 24.161215292632214 24.995371640635053 25.0 21.0 55.0 51.0 32.0 33.0 25.0 33.0 35.0 32.0 35.0 25.0 32.0 27.0 21.0 27.0 76.0 38.0 62.0 25.0 31.0 22.0 29.0 32.0 2.0 1.0 2.0 2.0 3.0 1.0 2.0 1.0 3.0 2.0 2.0 2.0 1.0 2.0 3.0 2.0 3.0 3.0 2.0 2.0 2.0 2.0 1.0 2.0 0.07824136742773646 0.9080725552559752 0.9266349541778063 GO:0006547 histidine metabolic process biological_process 27.804025495082012 25.36368489208928 26.640992235882496 25.33479728278729 26.20515586563589 23.262219687859663 27.577862285554648 25.653030038264074 28.193265349446012 24.66684195214639 28.27653933609455 25.99889333137792 27.98079085278516 24.461845673558308 28.146260929154 23.67115334092987 27.2693415286234 20.99626690869468 27.507470181158425 27.458351679570608 25.76663804271009 25.740815060751647 28.90048022298134 21.42346941671312 28.275678851420608 25.156829498334986 26.0 23.0 39.0 28.0 60.0 39.0 98.0 39.0 100.0 35.0 93.0 24.0 98.0 26.0 62.0 12.0 76.0 91.0 48.0 35.0 73.0 8.0 86.0 34.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.4403406029927304 0.00010962068302139599 0.000648372570666835 GO:0006548 histidine catabolic process biological_process 27.795991528138927 25.39892682013365 26.640992235882496 25.328362928730105 26.182190117868128 22.459481361136927 27.575035807095517 25.575982229674462 28.189644881218534 24.50661162634816 28.27435156785643 25.92152406028293 27.97690960929625 24.385178084308553 28.145372837079744 22.72222727360119 27.26672776686707 19.9986051726425 27.454215622314592 27.442879601150068 25.762523191345178 25.66140743280765 28.894123268961767 NA 28.26555303424251 25.10008033451541 26.0 22.0 33.0 14.0 58.0 32.0 93.0 25.0 96.0 29.0 90.0 21.0 97.0 16.0 60.0 5.0 67.0 83.0 47.0 27.0 68.0 NA 83.0 26.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.397064708005278 0.00017383318364122836 0.0008236168584623857 GO:0006553 lysine metabolic process biological_process 26.545645032607926 25.35699258899914 24.02503474268171 24.737934747971984 23.833894733339573 24.60391957997965 27.008226302476547 25.38785333482377 26.899155634738307 24.78911346843997 27.301809729627124 25.327372469230017 27.103178566340603 25.44316575706059 26.98420900177728 25.453511482270983 26.83052670263607 25.3988663163041 25.88875759919652 26.42269145153957 25.00423275563819 24.209746359081432 26.40834026731719 25.83420661529129 27.027041323866445 25.33188073002495 33.0 39.0 33.0 47.0 47.0 60.0 30.0 49.0 41.0 64.0 57.0 47.0 40.0 55.0 35.0 54.0 69.0 62.0 68.0 42.0 58.0 57.0 50.0 51.0 3.0 3.0 3.0 3.0 3.0 1.0 3.0 1.0 3.0 3.0 3.0 1.0 3.0 1.0 3.0 1.0 3.0 3.0 3.0 3.0 3.0 1.0 3.0 1.0 1.1886524436087846 0.02824036873330045 0.04901805310036017 GO:0006556 S-adenosylmethionine biosynthetic process biological_process 23.172350948677725 23.258143624417247 22.07194188657111 21.0416528014078 20.73747051569613 22.061691934704765 23.39078943546485 23.499536226799325 23.51740816863532 23.44228472306021 23.441994106406803 23.621339138537845 23.10560841582989 23.03042641212793 23.024284591256386 22.402551371761927 23.069703559051906 23.524039618054857 24.458851954598302 24.16981529060177 21.323989772433084 22.471301155059706 23.11236442811757 23.979450251407727 23.488011647528914 23.294369116835288 9.0 4.0 6.0 5.0 14.0 12.0 17.0 10.0 16.0 10.0 15.0 10.0 17.0 11.0 12.0 14.0 20.0 23.0 7.0 9.0 12.0 10.0 13.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.08579267573952265 0.5253727863737021 0.6008633207515945 GO:0006560 proline metabolic process biological_process 22.9505479041455 21.56812301816813 18.276908395037765 18.95377187854764 25.57145019160265 24.36184679205357 19.44272893314809 20.416637347499915 21.905634090507785 18.93022909447416 21.805098807672085 21.225581876541817 21.461898823484923 21.911575813187294 NA 20.536922857009472 18.431159657804024 19.716721807332245 23.338271119255058 19.99833758355766 23.099928595956825 19.431512150246817 22.86496433074578 20.93980075268066 17.63227060095765 19.60588823269657 2.0 2.0 43.0 33.0 5.0 9.0 14.0 3.0 14.0 10.0 12.0 12.0 NA 7.0 3.0 6.0 30.0 7.0 26.0 3.0 28.0 12.0 3.0 6.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 NA 1.0 1.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 1.3824248859773682 0.46018093544712035 0.5412872831649446 GO:0006563 L-serine metabolic process biological_process 25.19891687008117 24.760497516484065 24.7674450150852 24.71483891559768 24.47296922543516 23.335408915937123 25.8511250217872 24.200424739393807 25.11121898552569 24.65463478117548 25.316627551120373 25.309448752048894 25.162710063897986 25.23319870696701 24.81508919551456 24.62996731217571 25.16570832646089 24.22895012685101 25.552023700578214 25.576364865784413 25.032195197957005 24.523448150592948 25.29035328773973 24.53546974736931 25.3414262881209 24.937829095834232 26.0 22.0 22.0 21.0 32.0 32.0 26.0 33.0 37.0 35.0 37.0 22.0 40.0 28.0 27.0 32.0 47.0 35.0 39.0 23.0 29.0 23.0 37.0 32.0 3.0 2.0 1.0 3.0 3.0 2.0 2.0 1.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 2.0 1.0 3.0 2.0 3.0 2.0 0.43841935359710504 0.02824036873330045 0.04901805310036017 GO:0006566 threonine metabolic process biological_process 24.332108381940497 24.910337362551182 23.26451122277198 24.220544826370894 23.146999104279285 23.90634073091445 23.347314053529463 25.03496779932591 21.73929678507596 24.44379234717853 24.375113002138466 24.86509962534749 24.16147310149449 25.313850036280297 25.432254467637865 25.29894352237231 22.34378174236864 24.847575367948146 26.554331670505398 24.879338208557034 23.199442487405747 24.180069870585257 23.72430847866405 25.91216481833089 22.68438594496835 24.7979168101296 22.0 28.0 27.0 27.0 28.0 51.0 13.0 45.0 34.0 46.0 41.0 40.0 28.0 42.0 21.0 44.0 62.0 54.0 37.0 32.0 41.0 47.0 30.0 47.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 2.0 1.0 2.0 2.0 -0.5782289806106853 0.009374768459434895 0.01937038251220985 GO:0006575 cellular modified amino acid metabolic process biological_process 27.39923314261138 25.71416408103895 25.485245372397703 25.688091495887328 25.33806323189332 24.52756265216485 26.5017849519026 25.51038341713645 26.771958558260827 25.64552189458466 27.37812046511018 26.085428598735383 26.48508379435235 25.96748246562069 28.54020087270401 25.389804955436453 26.60825898805901 25.05446414699473 29.433416874207968 26.76749007050672 25.4893455975486 25.031209036326576 27.243829509926645 25.64867104334105 26.98709975303339 25.96009260719193 57.0 49.0 41.0 58.0 69.0 97.0 77.0 94.0 82.0 85.0 80.0 66.0 100.0 83.0 56.0 69.0 114.0 113.0 76.0 44.0 76.0 84.0 93.0 90.0 3.0 3.0 2.0 2.0 4.0 3.0 3.0 5.0 3.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 5.0 5.0 3.0 3.0 3.0 4.0 5.0 4.0 1.685069061572431 0.011074437676156606 0.022291771322328135 GO:0006576 cellular biogenic amine metabolic process biological_process 25.37825588401461 25.98453422474291 24.49982462099736 24.650295156833696 17.665711003977197 22.407153901896095 25.47615252001417 25.573797114800712 24.70654902076044 24.97270821979437 25.56015866375728 25.245844810585137 23.335897546092983 18.711778537110863 21.64963782669577 26.47074237614585 24.039123082242842 24.581237758932442 27.96108296389845 28.57319143907637 25.8307415183187 19.094183276675306 23.77186264129168 26.80657252548368 23.177472592257534 22.59132648772624 9.0 5.0 2.0 12.0 17.0 15.0 26.0 21.0 18.0 17.0 14.0 6.0 12.0 21.0 12.0 15.0 93.0 53.0 21.0 3.0 12.0 15.0 14.0 6.0 3.0 3.0 2.0 3.0 4.0 3.0 5.0 4.0 4.0 5.0 5.0 2.0 3.0 3.0 4.0 3.0 4.0 5.0 4.0 2.0 4.0 3.0 4.0 3.0 -0.6062783407282986 0.6441672226837103 0.7073013587238495 GO:0006605 protein targeting biological_process 23.48103597471401 23.223305950220002 23.032573410905773 23.644267485138197 22.384414037702445 21.914499855345856 24.438370344951274 22.166316322449564 21.745406580692144 23.118042440576573 24.071287846399738 23.553070239114682 24.256271611948552 23.33814058918413 23.691133703198552 23.16439925276926 22.128641574282007 22.75136799942874 22.10211174532469 24.35819824971561 22.064425482905687 22.29668356671873 22.81215728680868 23.045677345845302 24.746527053751286 23.51059561739523 11.0 13.0 9.0 8.0 17.0 12.0 9.0 19.0 18.0 28.0 19.0 14.0 9.0 17.0 18.0 12.0 17.0 25.0 13.0 16.0 12.0 12.0 24.0 28.0 NA NA 2.0 NA 3.0 2.0 NA 2.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 3.0 2.0 0.25773002449400906 0.9539596927720386 0.9577970205788449 GO:0006629 lipid metabolic process biological_process 29.90040293587908 29.774570052565174 29.23459512647517 27.087819506131034 27.39679332001189 28.18226790596045 29.485034051565822 29.780523655536882 30.352859973132787 30.79044084147975 29.9077259400958 30.399020256462173 30.36957274103765 29.458390986031326 30.14070347864205 29.222533250932738 29.641010252952576 29.87181198101553 30.38821852393837 29.99548161792884 29.94490147159345 29.290837781271826 30.36345632525725 29.797150673844705 29.677689932487784 30.35357321676853 393.0 184.0 202.0 391.0 590.0 534.0 839.0 612.0 703.0 574.0 769.0 443.0 663.0 497.0 605.0 636.0 940.0 752.0 525.0 477.0 770.0 512.0 705.0 580.0 3.0 3.0 3.0 4.0 5.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 5.0 5.0 4.0 4.0 3.0 3.0 4.0 4.0 5.0 5.0 0.12583288331390463 0.5253727863737021 0.6008633207515945 GO:0006631 fatty acid metabolic process biological_process 27.26898386308865 26.66385276351731 26.36145206782345 25.37257703398356 25.7755178974493 25.86963853382031 26.89952716033631 26.68494928141909 27.230166615194047 27.130725178661017 27.454956510924426 27.30404397235331 27.69301539181387 26.68036107006158 27.124334797959968 26.31049361930901 26.981649278566326 26.729071592792195 28.270640838930568 26.99525814781375 27.356421406388034 26.172309213473028 27.422935540331732 26.741721184469128 27.245064427749053 26.91954211712736 44.0 33.0 60.0 64.0 79.0 65.0 84.0 63.0 80.0 64.0 72.0 42.0 82.0 61.0 66.0 66.0 119.0 83.0 56.0 53.0 79.0 51.0 74.0 65.0 1.0 1.0 2.0 4.0 4.0 2.0 3.0 2.0 4.0 4.0 4.0 2.0 4.0 1.0 3.0 4.0 4.0 4.0 2.0 1.0 5.0 3.0 3.0 4.0 0.6051310995713415 0.01531382171343201 0.02967647437634029 GO:0006633 fatty acid biosynthetic process biological_process 27.103340487368307 26.636958463194713 26.36145206782345 25.37257703398356 25.7089725152629 25.760813144242157 26.743960648704864 26.64584859957344 26.935561159870915 27.126141352443717 27.36061794910541 27.29890603912325 27.594898845617703 26.68018177763315 26.58926218210815 26.295615391517728 26.948715626449513 26.725012371534024 27.877244381817235 26.89999831589517 27.3522208752634 26.172309213473028 27.362729655553068 26.68841575558184 27.1832945216314 26.90387701929448 44.0 33.0 54.0 54.0 67.0 57.0 73.0 61.0 69.0 60.0 65.0 41.0 63.0 59.0 59.0 63.0 104.0 71.0 53.0 53.0 64.0 49.0 68.0 61.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.4663820241735941 0.03766692222862868 0.06276144050911694 GO:0006637 acyl-CoA metabolic process biological_process 28.456951789905805 27.010999968859164 26.616519403375055 24.96605144092502 26.16150204685564 25.580837939499155 28.31569634905726 27.130443351168772 29.021117208629608 27.852237193006506 29.101367926370074 27.14472028589622 28.825408777187 26.450754916399994 28.83716051987162 26.846180774614677 28.12661091245107 27.16243765210537 28.41284714094337 27.39091887305428 27.910529491155323 26.761710578214487 28.630708200139622 26.712942856315365 28.940563563309244 27.83859909485662 95.0 49.0 79.0 51.0 174.0 132.0 193.0 88.0 174.0 117.0 173.0 74.0 178.0 121.0 128.0 104.0 229.0 185.0 133.0 94.0 173.0 110.0 180.0 93.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 1.4459518210466413 0.0022136919545913893 0.006045268182341475 GO:0006643 membrane lipid metabolic process biological_process 23.952897374114517 24.688484972893125 23.895292726690982 22.93240514705508 24.08839362561232 25.574016312240342 22.746747533271407 24.538180667173403 24.285039855015693 24.487178673616253 23.659596788573083 24.427925779598866 24.04675897494958 24.6663880158058 24.25716980995194 25.339632798369497 23.5462399299022 25.01845519023161 24.558531975980745 23.62810727682468 22.95290670945353 24.73101255293929 24.45667427596245 25.247426238001164 23.858052960849943 23.55590873372843 18.0 15.0 15.0 66.0 24.0 24.0 39.0 24.0 30.0 24.0 42.0 18.0 30.0 39.0 24.0 24.0 51.0 36.0 12.0 30.0 39.0 24.0 30.0 27.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.7355875987786078 0.024343383653741054 0.04309296851045225 GO:0006644 phospholipid metabolic process biological_process 28.05163469349923 28.105346152087908 27.513526912416395 23.700605339522923 23.770136416771752 25.483232697590214 27.595064504768928 28.137286371081416 28.655833344048705 29.3271045742128 27.963492320145697 28.78753307279387 28.540011918301534 27.549863643058142 28.437712658655826 27.35740927227345 27.78688310818023 28.2093919343606 28.28997702769464 28.329178704140467 28.143968831960173 27.58860488984065 28.65609826450857 28.03200182843183 27.659751324974607 28.83932081675109 121.0 32.0 22.0 62.0 157.0 158.0 248.0 187.0 201.0 176.0 227.0 134.0 181.0 129.0 171.0 190.0 255.0 213.0 163.0 131.0 227.0 154.0 200.0 168.0 5.0 3.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 -0.05371145858867621 0.8624902301359216 0.8917877441670506 GO:0006650 glycerophospholipid metabolic process biological_process 22.394088063670416 22.73898533809584 22.60753681362927 22.34148625535209 20.256418717533762 22.421228653553992 22.264545988816653 23.10332437317017 18.385059794716085 22.213594252831665 22.38157851931557 22.65324609098325 24.104019511509204 23.306350308276386 21.078072658570548 22.737595751991698 20.59326280592427 23.268370750458818 23.24674797987473 22.331741053037707 22.1723176882601 20.5457733633004 22.61194270461523 23.669011511428728 22.175238174762868 22.24881947192104 10.0 12.0 6.0 10.0 18.0 8.0 4.0 13.0 17.0 18.0 21.0 21.0 11.0 15.0 7.0 41.0 46.0 19.0 13.0 7.0 15.0 16.0 19.0 13.0 2.0 3.0 2.0 2.0 4.0 NA 3.0 3.0 4.0 4.0 3.0 3.0 3.0 2.0 3.0 2.0 5.0 3.0 3.0 2.0 3.0 2.0 5.0 3.0 -0.34489727442542417 0.11903289845700783 0.16804644488048165 GO:0006664 glycolipid metabolic process biological_process 23.367934873393363 24.10352247217197 23.310330225969828 22.347442646333928 23.50343112489116 24.989053811519195 22.161785032550245 23.953218166452245 23.700077354294528 23.902216172895088 23.074634287851925 23.842963278877697 23.46179647422842 24.08142551508465 23.67220730923078 24.754670297648342 22.961277429181038 24.43349268951045 23.973569475259584 23.043144776103524 22.367944208732386 24.146050052218126 23.871711775241288 24.66246373728001 23.27309046012879 22.97094623300727 12.0 10.0 10.0 44.0 16.0 16.0 26.0 16.0 20.0 16.0 28.0 12.0 20.0 26.0 16.0 16.0 34.0 24.0 8.0 20.0 26.0 16.0 20.0 18.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 -0.7355875987786078 0.024343383653741054 0.04309296851045225 GO:0006720 isoprenoid metabolic process biological_process 27.04322289583615 27.00296687395083 26.38903034845914 22.068205404414734 21.184083086033766 22.007520679798613 26.661185044852648 26.988447318793483 27.822617762399588 28.28735068725107 26.953048172467717 27.713719363904467 27.456825730623976 26.56199804155126 27.506232662766905 26.033628689561947 26.78269571850204 27.044121631739202 27.13786822808884 27.3169256040909 27.05517256764032 26.465036305178728 27.657485274330917 26.875299787823266 26.670022877244712 27.8103482337617 46.0 7.0 4.0 12.0 64.0 65.0 120.0 80.0 76.0 64.0 84.0 51.0 90.0 46.0 71.0 66.0 73.0 90.0 64.0 58.0 90.0 57.0 76.0 68.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.040256021885319626 0.7290344895388041 0.7743276961229171 GO:0006725 cellular aromatic compound metabolic process biological_process 35.43402906485904 36.18582596390641 35.566805224901664 35.575916775905235 35.22903775505063 36.12445894576221 35.074108273479446 36.35748393758036 35.02029002454319 36.094125902237955 35.60072402300309 36.07716634132942 35.561381765732925 35.741987022217934 35.83330241965027 36.55014257888251 34.98172159286749 36.60679590157481 35.97334725723924 36.37714425667643 35.35484357060842 36.05598750786577 35.216697484484165 36.277585586340244 35.40731196738601 36.05214736880117 22917.0 23133.0 22650.0 28090.0 25553.0 36648.0 28755.0 33819.0 29827.0 33940.0 32128.0 26127.0 31787.0 34518.0 25058.0 35122.0 39474.0 37995.0 29124.0 29156.0 30114.0 31794.0 30765.0 34533.0 12.0 13.0 10.0 13.0 11.0 12.0 11.0 11.0 12.0 13.0 13.0 13.0 11.0 13.0 11.0 13.0 12.0 12.0 11.0 11.0 12.0 13.0 12.0 13.0 -0.7517968990473705 0.00010962068302139599 0.000648372570666835 GO:0006732 coenzyme metabolic process biological_process 30.907113766706075 31.389745673046193 30.86353337847093 30.729917527985894 30.56595699741486 31.39582158698865 30.457542624944573 31.604015408320212 30.45714262924267 31.292473500222894 31.10625574011011 31.232066849738846 30.814427599241913 30.841289811484003 31.589853585590767 31.73329637488905 30.33114734115009 31.88580464056157 31.709551039122843 31.648280576886762 30.843484268823012 31.26347271739529 30.511474391750635 31.39346389142561 30.83791334598745 31.227159924069447 650.0 633.0 690.0 740.0 848.0 1049.0 955.0 871.0 906.0 930.0 904.0 759.0 1096.0 962.0 735.0 844.0 1328.0 1130.0 864.0 770.0 898.0 932.0 932.0 854.0 9.0 10.0 8.0 12.0 9.0 10.0 13.0 12.0 11.0 14.0 12.0 14.0 13.0 12.0 13.0 10.0 11.0 11.0 8.0 10.0 12.0 13.0 14.0 15.0 -0.4826319063401172 0.007911788680711459 0.016907384030013527 GO:0006753 nucleoside phosphate metabolic process biological_process 34.53238584378891 35.35745736382264 34.73446384908185 34.707782214010116 34.37736816197928 35.30383748988265 34.15105952525875 35.53541893670345 34.036537632017414 35.26646120848326 34.671912674481675 35.238426940173674 34.624124075344 34.86795524285751 34.9728602412687 35.74342382362278 34.093110574982575 35.825537063273366 35.10723527673555 35.52290379097893 34.4893237681836 35.23946218143342 34.188222122213986 35.43365865619964 34.481011567054736 35.2191808795778 11705.0 11621.0 11625.0 14146.0 12952.0 18693.0 14391.0 17170.0 14852.0 17158.0 16078.0 13051.0 16222.0 17408.0 12973.0 17848.0 19860.0 19075.0 14936.0 14919.0 15269.0 15949.0 15606.0 17525.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 -0.8250715200337311 0.00010962068302139599 0.000648372570666835 GO:0006754 ATP biosynthetic process biological_process 28.931727827169013 30.017313292307172 29.35412622445281 29.320781574424768 28.972594594421267 30.040547906274252 28.380664954343768 30.19811893029263 28.114103237477927 29.891265444886564 28.86165918579904 29.888712901016692 28.74748883474229 29.370908565986962 29.493616666705627 30.45132586759711 28.458976211281318 30.57209013032108 29.69743146433301 30.16137400144254 29.01099497676991 29.922723967649198 28.49087699421257 30.024706424927462 28.71135981176432 29.85993376327197 202.0 187.0 215.0 259.0 203.0 296.0 242.0 270.0 235.0 261.0 221.0 184.0 279.0 258.0 193.0 267.0 317.0 295.0 254.0 250.0 236.0 219.0 221.0 273.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.0855854651381591 0.00010962068302139599 0.000648372570666835 GO:0006760 folic acid-containing compound metabolic process biological_process 27.375047457782568 25.56070860523421 25.44638555011619 25.36830322511715 25.32994828790939 24.457000253929944 26.486499326522022 25.243918577025948 26.74595145730657 25.361000654043607 27.359919285247607 25.975698648037554 26.434165030660377 25.86594272434525 28.534243200076 25.28989063291607 26.590434895725412 24.834745580455042 29.40614688584912 26.684471173811563 25.443130993660198 24.9675211638979 27.199534929076442 25.494588773455728 26.95859984231832 25.807271578572745 51.0 45.0 39.0 57.0 65.0 84.0 67.0 75.0 75.0 72.0 71.0 56.0 95.0 72.0 49.0 56.0 91.0 100.0 71.0 39.0 67.0 75.0 80.0 76.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 1.0 3.0 3.0 3.0 3.0 1.8143388525483566 0.00268017172806849 0.006910856026093958 GO:0006766 vitamin metabolic process biological_process 27.276178934341587 26.431090740149077 23.08819176925959 25.187310005956512 26.16463474321808 25.644307121407145 25.96285999312786 26.976296399908534 27.12472514693962 27.122134611217803 27.33636376683054 26.49235788884989 26.98629434777728 25.67793769768775 28.167852172880202 26.948844688259076 26.30179305248977 26.74887333650032 28.998834409357553 26.31979655951225 25.486038860779143 25.56273647039712 27.826377529128973 26.45696083035761 27.125595158174487 26.59197692508893 45.0 87.0 40.0 116.0 173.0 241.0 217.0 211.0 203.0 190.0 245.0 140.0 196.0 230.0 181.0 223.0 299.0 221.0 133.0 115.0 257.0 256.0 307.0 182.0 2.0 2.0 2.0 3.0 2.0 2.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 2.0 3.0 3.0 2.0 3.0 3.0 0.8450881941925097 0.16585666034291002 0.2267131567447445 GO:0006767 water-soluble vitamin metabolic process biological_process 26.71420899478241 25.895213821736625 22.564319727913237 24.70296102461081 25.59753481597733 25.149596922086634 25.41162776057081 26.42132833669777 26.597896410564772 26.554578363928233 26.791824405302183 25.95059257614573 26.430761001873737 25.150976079733766 27.58841734263636 26.435133561996487 25.742905113563122 26.224642641756876 28.42102926643543 25.765665832957392 24.95905906967432 25.02255988173869 27.257291357696747 25.96331413692041 26.58903677794152 26.02141869412177 31.0 62.0 28.0 83.0 119.0 165.0 147.0 143.0 140.0 132.0 167.0 98.0 132.0 163.0 123.0 155.0 207.0 151.0 92.0 79.0 176.0 181.0 210.0 124.0 5.0 6.0 6.0 7.0 8.0 6.0 9.0 8.0 7.0 9.0 9.0 9.0 8.0 8.0 9.0 6.0 8.0 8.0 6.0 7.0 9.0 8.0 9.0 9.0 0.818995173045785 0.18420928818665294 0.2488021554728819 GO:0006778 porphyrin-containing compound metabolic process biological_process 23.889472288447266 23.84246145615146 20.769330824514423 22.058936281929864 22.83619228563505 20.752707539951626 23.32183541406972 23.200700881267203 23.21785773181646 25.194275070074386 23.88810926704909 24.469020705400663 25.190589139815998 24.27395891164134 22.577354935286245 22.338984756070342 23.25633800766674 23.01209012124127 24.888944035191297 24.042572812373642 23.717259272183 22.434767165789427 23.869984129992794 23.26312221505929 24.668947195925533 25.103233770101518 9.0 2.0 21.0 10.0 33.0 30.0 39.0 66.0 40.0 48.0 80.0 35.0 14.0 17.0 32.0 22.0 79.0 59.0 45.0 12.0 71.0 31.0 73.0 56.0 3.0 2.0 5.0 2.0 5.0 3.0 5.0 5.0 3.0 3.0 5.0 5.0 3.0 3.0 3.0 3.0 5.0 5.0 5.0 3.0 3.0 3.0 5.0 3.0 0.04701083229580405 0.6441672226837103 0.7073013587238495 GO:0006779 porphyrin-containing compound biosynthetic process biological_process 22.86831539083921 22.98410761531672 20.3269990057745 NA 21.72471154202482 19.946287761053906 22.35511213133641 22.339347850313054 22.160993069469185 24.124529302046195 23.012398270079647 23.706512907136982 24.18393892906633 23.25392005602129 21.74289019697752 21.323926898355435 22.188967919959726 22.35003368345186 23.92406147422941 22.80500231755895 22.64615455581648 21.567426977319336 22.75741418350965 22.7901078342216 23.475649507099792 24.044737905756694 4.0 NA 12.0 6.0 15.0 15.0 19.0 30.0 21.0 24.0 36.0 16.0 8.0 10.0 14.0 12.0 39.0 26.0 21.0 6.0 32.0 17.0 31.0 27.0 2.0 NA 2.0 1.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 -0.11579222447750936 0.8535135775742164 0.8883944493850059 GO:0006782 protoporphyrinogen IX biosynthetic process biological_process 22.12263878754928 21.103036276403085 16.811719292074706 NA 21.13321575727557 19.52906731741765 21.976985319005003 20.453134109640544 21.142469571621163 21.862723182261924 22.66351285793037 21.721334714791478 23.140922136772808 21.505025656205568 21.28775045377861 19.06934215359692 21.713574631926733 20.220731984908703 23.286364773617894 20.84941747995923 22.017095637337622 20.73682063129472 21.7641782564322 20.35437377165572 22.519166244766673 22.413835350049567 1.0 NA 6.0 4.0 10.0 5.0 7.0 13.0 12.0 10.0 19.0 7.0 4.0 3.0 6.0 4.0 23.0 11.0 13.0 2.0 15.0 6.0 15.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0196025111461964 0.026715698447179453 0.047158686933635015 GO:0006790 sulfur compound metabolic process biological_process 29.501128530787557 28.261956718672113 27.59300313489167 26.78762264949173 27.083643566589128 27.351593796150368 29.54089625840377 28.39892083173521 30.148418441424926 28.75094135021684 30.17171438655453 28.472658551090216 29.836665182709947 28.077814375970828 29.8722100139003 28.199407463565198 29.21083038126309 28.348010457366147 29.431500074874357 28.56638169827248 28.71531982882 27.97151529747481 29.662597433435 28.477248046557694 29.91931993338284 28.678829633949604 249.0 180.0 217.0 229.0 436.0 440.0 478.0 303.0 461.0 418.0 477.0 317.0 432.0 395.0 316.0 374.0 621.0 518.0 343.0 285.0 470.0 407.0 466.0 335.0 12.0 8.0 7.0 10.0 11.0 11.0 9.0 11.0 13.0 13.0 11.0 11.0 9.0 12.0 11.0 10.0 15.0 11.0 11.0 12.0 11.0 13.0 13.0 11.0 1.239171812115444 0.003892417122778628 0.009377869824763952 GO:0006793 phosphorus metabolic process biological_process 35.94994284211026 36.7582544950141 36.13386988100285 36.100290408280614 35.76659203500812 36.68980933951809 35.569350196854685 36.93715911282439 35.480396386011044 36.68247369195536 36.09056834349351 36.65270467110429 36.05145624437716 36.27333158951828 36.38132493544697 37.137002480130704 35.5100939437846 37.21863875055981 36.52071747511681 36.923554570267314 35.93138736781668 36.63780401361614 35.62516420495996 36.8340983376532 35.89266972925188 36.63218743624448 31393.0 30982.0 30764.0 37564.0 34882.0 49999.0 38903.0 46134.0 39954.0 46168.0 43341.0 35049.0 43589.0 46524.0 34941.0 47874.0 53535.0 51296.0 40135.0 39868.0 41159.0 42779.0 42006.0 47025.0 6.0 5.0 5.0 5.0 7.0 7.0 6.0 6.0 7.0 6.0 7.0 7.0 7.0 6.0 6.0 7.0 7.0 7.0 7.0 6.0 7.0 6.0 7.0 7.0 -0.8083116529038392 0.00010962068302139599 0.000648372570666835 GO:0006796 phosphate-containing compound metabolic process biological_process 34.8278136004943 35.64247414090629 35.020413321225966 34.984981421524246 34.65307428256897 35.57822567700993 34.44197914206745 35.82196110493128 34.351999503554694 35.56408536366383 34.963795997919156 35.53367335440033 34.92241569708513 35.15289052846564 35.26911551693768 36.02246030260964 34.386704518053776 36.10689340746951 35.40200368834782 35.80927679435779 34.800782381200264 35.523484155033 34.497475066319154 35.71457401399741 34.769244610798275 35.513774466882154 14300.0 14114.0 14067.0 17137.0 15889.0 22803.0 17727.0 21008.0 18203.0 21000.0 19710.0 15938.0 19904.0 21179.0 15909.0 21792.0 24410.0 23349.0 18295.0 18176.0 18746.0 19451.0 19107.0 21383.0 14.0 16.0 14.0 15.0 19.0 15.0 16.0 16.0 19.0 17.0 17.0 17.0 16.0 16.0 18.0 16.0 19.0 16.0 17.0 14.0 18.0 16.0 19.0 17.0 -0.8146605404119853 0.00010962068302139599 0.000648372570666835 GO:0006807 nitrogen compound metabolic process biological_process 36.197377129995935 36.72128358435467 36.14416949520335 36.0954619869039 35.808322137521095 36.64867475041761 35.82327975534974 36.859829173440716 35.92792978732957 36.608190962868534 36.3893507415563 36.67832614817461 36.33877487485443 36.329900146209866 36.58031864594636 37.06092689420342 35.7461834073438 37.08426589596952 36.76951786142253 36.946413539037344 36.09736761599725 36.57439478677221 36.185580810096134 36.857495122605435 36.16677050217077 36.600915741554495 35536.0 34514.0 34064.0 43610.0 39794.0 54959.0 46075.0 51663.0 47180.0 52607.0 50504.0 39832.0 51417.0 52383.0 39185.0 53378.0 61973.0 59131.0 45669.0 43602.0 48423.0 49060.0 47811.0 52791.0 5.0 4.0 5.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 6.0 6.0 5.0 6.0 5.0 6.0 5.0 -0.5239064543587375 0.0018227351663913985 0.005134928866041682 GO:0006810 transport biological_process 30.76988039214489 31.39942404314518 30.5096085761868 30.999431750225714 30.44142837297059 31.04288809520985 30.458921859934645 31.363692714892732 30.586687114253483 31.31077175082804 30.921304886962808 31.48769407376293 31.03379456232532 31.201524609149352 30.678170402188748 31.754257576682114 30.47429534714088 31.538275031757703 31.126532176988512 31.567234207434076 30.992031127655487 31.229637434846648 30.788584927057986 31.498243539880107 30.98064430915607 31.59748997769471 1366.0 1339.0 1287.0 1457.0 1381.0 1621.0 1566.0 1784.0 1653.0 1848.0 1797.0 1461.0 1705.0 1690.0 1261.0 1691.0 1818.0 2045.0 1590.0 1559.0 1641.0 1586.0 1780.0 2177.0 10.0 10.0 7.0 9.0 11.0 8.0 9.0 11.0 11.0 11.0 12.0 11.0 13.0 9.0 8.0 9.0 9.0 10.0 9.0 8.0 10.0 10.0 11.0 11.0 -0.6295436510002901 6.784570247173055e-05 0.0005498145239267514 GO:0006811 ion transport biological_process 29.60040401468256 30.332128065891556 29.14053439621026 29.53700758874157 28.812159538576587 30.11116171561897 29.30247829783674 30.38634033937979 29.45935720258135 30.34695843351891 29.75537263489745 30.4464794535991 29.838252285897397 29.851115150949017 29.39080084417614 30.759415241230112 29.46326089513277 30.69337625565165 30.13637941581767 30.332996938020848 30.0626828772189 30.184449137484325 29.64937508512013 30.42768634110807 29.66353338692013 30.49189262586926 467.0 446.0 434.0 561.0 507.0 627.0 615.0 628.0 577.0 647.0 610.0 501.0 632.0 621.0 445.0 607.0 632.0 737.0 590.0 565.0 599.0 511.0 605.0 702.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.731724051208996 0.0002755038114342687 0.0011655212090507369 GO:0006812 cation transport biological_process 28.67481363785455 29.39082528189983 28.203401509687037 28.536916775974873 27.893034526061488 29.10603480517336 28.377202694577175 29.46028800072748 28.61683283685727 29.464799842192978 28.80310475195041 29.504418396338345 28.868054398508395 28.910435199285807 28.48011400266889 29.79512176095389 28.6698022294582 29.76449721276704 29.17681062471952 29.399019669333573 29.035088213455964 29.229625149596227 28.768626069630017 29.45318304753369 28.744161962168466 29.60740593900568 241.0 227.0 222.0 280.0 279.0 325.0 332.0 333.0 315.0 339.0 332.0 267.0 333.0 319.0 241.0 316.0 317.0 391.0 305.0 287.0 323.0 265.0 330.0 378.0 4.0 8.0 5.0 7.0 7.0 7.0 8.0 5.0 9.0 10.0 10.0 7.0 5.0 7.0 8.0 7.0 5.0 7.0 6.0 5.0 9.0 9.0 7.0 8.0 -0.7160116440452775 0.00042856814449695465 0.0016457016748683058 GO:0006817 phosphate ion transport biological_process 20.148077773459715 22.02249196994083 19.941932709855934 23.228121433042787 21.923419507655396 23.287161144877075 NA 21.870519531222413 18.37220365875397 20.35485873983652 NA 20.963972946010628 18.803612522068786 22.281958609368925 20.621887206439247 21.89863211603065 NA 19.89976953447046 19.991576429499847 21.735454701622366 20.58165736160936 22.222268545052923 18.285627548037528 21.938659703010263 16.99712987953713 20.46591566231953 5.0 11.0 8.0 9.0 NA 12.0 1.0 7.0 NA 7.0 3.0 11.0 7.0 12.0 NA 7.0 3.0 10.0 6.0 10.0 1.0 8.0 1.0 6.0 NA NA NA 1.0 NA NA NA NA NA NA NA 1.0 NA 1.0 NA NA 1.0 NA NA NA 1.0 NA NA NA -1.8744141964811156 0.005577994003398269 0.012692811975156102 GO:0006820 anion transport biological_process 23.44530011054234 23.490457226986685 21.13180941892698 23.936971787622237 21.95464169815144 23.565120073391284 21.70000634869468 23.67801237088428 23.73316777791388 22.608659936758965 23.76717124272941 22.995556856944322 22.938705914553278 24.009535444109 24.52786062362823 23.48904643142836 23.473045138631267 22.364051838766006 23.844810424408365 23.72863609179905 23.366089422105087 22.891063040628467 22.6300769663819 24.08884449651851 24.4444856717289 23.41544303148097 10.0 24.0 9.0 15.0 8.0 30.0 16.0 18.0 8.0 30.0 21.0 32.0 21.0 33.0 13.0 22.0 21.0 29.0 19.0 22.0 17.0 33.0 18.0 21.0 3.0 2.0 2.0 3.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 -0.045157116444343615 0.6861059569955559 0.7413508522341591 GO:0006865 amino acid transport biological_process 21.747341638441558 22.680469049073015 19.35811654454444 22.53909900305485 16.409007952038213 19.94382458232368 21.63061450821379 23.11451381131857 21.101368131921124 22.269185304149648 20.68792233652892 22.54825468775289 22.54715884543925 23.373094474311646 23.19244842742556 22.48174127859486 21.79176548566232 22.07562094047244 22.0721708474198 23.06193462931404 22.178278687285342 21.30088507460752 21.59214615592475 23.40023899303604 21.33156597895976 23.21544124139294 3.0 12.0 1.0 2.0 5.0 17.0 7.0 11.0 5.0 22.0 12.0 18.0 7.0 14.0 8.0 15.0 7.0 15.0 8.0 11.0 8.0 22.0 9.0 15.0 1.0 1.0 1.0 1.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 2.0 2.0 1.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 -0.9331274106314567 0.01531382171343201 0.02967647437634029 GO:0006879 cellular iron ion homeostasis biological_process 25.96041406265681 26.134966822063546 24.46348717405848 27.029141037508268 26.290722119021783 26.489562666456198 27.305465680533064 24.818248311626462 25.283929736338525 25.543977585875503 23.296115684737305 22.116409803784013 27.052600115130854 26.69016117441853 25.07818154273459 26.506441878330932 24.8261663607268 25.18754635236632 25.45007287090927 27.235110306787696 24.868103504447564 26.67502803276578 27.04169634822499 23.35623585979761 25.333435338074803 25.642232211123385 2.0 2.0 2.0 5.0 8.0 6.0 3.0 4.0 3.0 1.0 3.0 5.0 1.0 1.0 4.0 3.0 3.0 4.0 3.0 4.0 5.0 2.0 4.0 5.0 NA 1.0 NA 1.0 NA NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA 1.0 NA NA NA NA -0.17455275940673687 0.6441672226837103 0.7073013587238495 GO:0006886 intracellular protein transport biological_process 25.761494862768828 26.341828698114988 26.06924940663034 26.622588779468483 26.22764339451668 25.40795124887583 25.613437430095075 25.85232881614518 25.510959138371 26.017822466220537 25.810987413190446 26.38021219485721 26.078472405424037 26.65412772966436 25.80465682196452 26.36434948463507 24.893764691155823 25.73810369847168 25.53043213789208 26.895999650212627 25.21474176365873 26.256307043394266 25.60376891649227 26.5800616428268 26.189910335274696 26.626161776629424 85.0 81.0 80.0 76.0 76.0 72.0 70.0 105.0 92.0 108.0 101.0 86.0 85.0 93.0 68.0 96.0 106.0 116.0 73.0 93.0 81.0 98.0 100.0 139.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 -0.5803338353461598 0.005583616806378765 0.012692811975156102 GO:0006950 response to stress biological_process 27.39882235272913 27.86068478349736 26.20844108140814 27.962673329645572 27.05902472824731 28.042384039965192 27.46706713031359 27.27558662068121 26.89810360433782 27.32581809075377 27.243350902698346 27.29020257956425 28.189649208102022 27.970201305940666 27.273614682430424 27.95887743843221 27.013917020695292 27.883745130584607 28.335409529544506 28.593150379752565 27.896720527230354 27.603684520458607 26.727420694506005 28.126322209564506 26.98726941571257 27.70294900426993 129.0 159.0 125.0 230.0 184.0 196.0 231.0 183.0 268.0 230.0 290.0 246.0 210.0 259.0 174.0 251.0 300.0 320.0 143.0 126.0 190.0 303.0 266.0 218.0 7.0 7.0 7.0 7.0 6.0 7.0 7.0 7.0 6.0 7.0 6.0 6.0 6.0 7.0 6.0 7.0 5.0 7.0 6.0 6.0 5.0 7.0 6.0 7.0 -0.4618624307682282 0.017926339076638688 0.03379466943753034 GO:0006952 defense response biological_process 19.468582811487007 20.288310131189526 16.5973256134569 20.468667809368664 15.83736094084413 21.009524130821323 20.063456638508548 NA 16.98888198283622 19.135077784899664 19.370007652720247 19.92493427020617 21.405138701774227 21.215727576037928 20.25204806952362 20.647152288934983 17.824360339383357 17.905197275163157 NA 19.181044495080226 17.296092461171643 NA NA 21.182837841367785 19.56368087320517 18.513200314275295 2.0 4.0 1.0 9.0 6.0 NA 1.0 1.0 5.0 3.0 15.0 5.0 7.0 12.0 3.0 1.0 NA 3.0 2.0 NA NA 7.0 4.0 2.0 1.0 2.0 1.0 2.0 2.0 NA 1.0 1.0 2.0 1.0 3.0 2.0 2.0 3.0 2.0 1.0 NA 2.0 1.0 NA NA 3.0 1.0 1.0 -0.819727319702519 0.09630369202868826 0.1410645629715997 GO:0006974 cellular response to DNA damage stimulus biological_process 25.608777014976212 25.871866638651053 25.48591663623905 25.80023398871918 25.328144551365625 26.15211077859596 25.1198758919458 25.50292137211264 25.183488881973663 25.23907362707696 25.479741635912728 25.99720767971265 25.575999697073755 26.041346325355374 24.815948892059367 25.88429596902409 24.819332766613787 25.684449827404947 25.566067412052988 25.98665863435899 27.234792558674226 25.43851186354198 25.15271992284677 26.35920387428565 25.560350310325504 25.992622803371873 77.0 88.0 82.0 113.0 70.0 94.0 110.0 82.0 134.0 114.0 127.0 171.0 77.0 137.0 66.0 112.0 86.0 116.0 66.0 65.0 87.0 161.0 144.0 99.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.26308962367484057 0.007911788680711459 0.016907384030013527 GO:0006996 organelle organization biological_process 28.485449954598582 28.69871793709596 28.33810630005485 27.8900050627419 27.747946985052447 28.08051581463388 28.399596056067313 28.449532128992672 27.789465423139852 28.86813255167103 28.120658360220823 28.97601486074905 28.49213536443594 28.656749545122885 29.393994792776088 29.28465275505773 27.729367070382715 28.567366597149853 27.99150125114245 28.572915260145887 29.560755379492946 28.845636204697875 28.702629438644447 28.939748410445965 27.986482264856118 28.711477092239512 46.0 48.0 48.0 54.0 54.0 50.0 48.0 44.0 75.0 69.0 74.0 96.0 52.0 87.0 39.0 55.0 76.0 73.0 59.0 42.0 65.0 89.0 73.0 80.0 4.0 2.0 4.0 3.0 5.0 2.0 2.0 2.0 4.0 2.0 4.0 4.0 5.0 3.0 3.0 3.0 2.0 4.0 3.0 3.0 4.0 3.0 6.0 2.0 -0.21326798249737777 0.0734883472918226 0.11239394291690516 GO:0007049 cell cycle biological_process 27.248614992680462 27.65855320621485 27.111826373648864 26.960675195958565 25.64293842918831 27.442908774384858 27.031264637226247 27.763220709538725 26.637826138429194 27.606077750137874 27.14522542568377 27.93508606102221 27.64093256598805 27.718045026558233 26.608793241622486 27.704352164427647 27.609965234438896 27.600609810978586 26.86095604432096 27.4942404460374 27.282609879236684 27.060985894881373 28.39323958804369 28.35367062034643 27.35701643588811 27.74849888082493 77.0 103.0 63.0 119.0 94.0 175.0 101.0 168.0 119.0 178.0 121.0 153.0 133.0 206.0 108.0 200.0 126.0 163.0 117.0 132.0 117.0 220.0 116.0 177.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.40993821353438875 0.024343383653741054 0.04309296851045225 GO:0007059 chromosome segregation biological_process 21.904885666643768 22.91983406901884 20.991691152833127 22.236822730242185 21.224014338811315 23.552827738135914 22.921181471289525 23.454929660571825 20.0065487994453 21.911176517136788 22.172382518473192 22.164895886591157 22.74831302063416 22.95441838612707 21.81425327922725 22.961372644047433 18.961319368135133 22.031485248960433 21.98141472005125 21.994352735421707 21.145743805549863 23.060262200260983 22.398888608121887 23.69622301646184 22.42436389628984 23.355418159834127 10.0 20.0 12.0 34.0 16.0 32.0 5.0 16.0 16.0 18.0 20.0 23.0 5.0 35.0 5.0 20.0 18.0 16.0 11.0 27.0 15.0 36.0 20.0 33.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0149484023750723 0.006656727227605034 0.01478219854101616 GO:0007155 cell adhesion biological_process 22.930668572607473 23.187297703529982 23.059139719061136 22.968456452372106 24.23262214811449 21.55511070637351 20.587252828341825 23.515060010409684 21.972968264181684 23.14384517947019 21.04222325767885 22.140976856783148 24.29931512682729 23.91510377678693 22.671295234867834 22.081929935890283 21.97098226989614 22.25579878697043 21.442733805928665 22.960229786158408 24.024005036164823 22.47087317602211 21.72222570539189 24.196703393068447 22.204228146038083 24.17809154892044 8.0 12.0 5.0 10.0 5.0 24.0 5.0 12.0 5.0 8.0 11.0 28.0 11.0 8.0 6.0 9.0 8.0 14.0 6.0 7.0 5.0 16.0 9.0 20.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.2566291309225086 0.24821307898992373 0.31935043564889154 GO:0008026 ATP-dependent helicase activity molecular_function 21.72735949125997 24.264866573559946 22.99070671007577 24.038147132451176 20.267583941869802 24.54189408723194 21.19874188569053 24.38814521198192 17.952487919804554 23.002546781001225 21.30753891436284 24.152788546721638 21.723312450301627 24.8222284931287 20.747644683098574 24.3057418385704 22.959853050797285 23.88859763814845 22.483421232671905 23.94412042587501 19.204890978557888 23.38830767114129 20.592745496871466 25.44194889591401 22.359401009200358 23.58712129346332 22.0 37.0 7.0 51.0 11.0 33.0 3.0 20.0 18.0 36.0 19.0 48.0 12.0 37.0 6.0 34.0 19.0 35.0 4.0 25.0 9.0 41.0 14.0 33.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -2.5375070822999746 3.225641456243767e-05 0.0005099643033035255 GO:0008033 tRNA processing biological_process 23.383986306718125 25.06962579793468 23.703656772342555 24.816327725463296 23.150531467720505 25.396598548831424 22.742271188437552 25.248648813612853 22.65853672340838 24.584769242056588 23.794648136533194 24.51192347079727 23.95327039984846 24.87208481630787 22.690510144006552 25.206380420727417 22.46344891553882 25.165117410275954 24.01136463203452 25.321182955053832 23.542300899455427 24.701016683295432 23.343989585842728 25.79362681551516 23.471378534474386 24.603499880292944 24.0 60.0 29.0 76.0 32.0 76.0 31.0 57.0 57.0 66.0 48.0 53.0 24.0 81.0 24.0 76.0 64.0 60.0 31.0 65.0 32.0 88.0 38.0 58.0 1.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 1.0 3.0 2.0 2.0 -1.6856394912165555 3.225641456243767e-05 0.0005099643033035255 GO:0008080 N-acetyltransferase activity molecular_function 23.743167487287455 24.804347630416693 25.814405390196747 24.230797043994716 24.099774906446747 24.680894256415485 21.27288444466624 24.972830589705357 21.505197465038208 25.19089345586486 22.535592662774402 24.71909440107645 23.13155589422114 24.255768737530733 24.99338850596583 24.97002232264904 23.13708809938392 24.568754564800486 22.21068997505307 24.983262527473308 23.357456464794392 25.381133773604606 21.215437781796943 24.322239407800808 23.263135493342947 24.863829185734865 18.0 12.0 24.0 26.0 7.0 24.0 7.0 21.0 10.0 17.0 13.0 15.0 22.0 21.0 8.0 21.0 9.0 19.0 17.0 24.0 8.0 18.0 16.0 27.0 3.0 3.0 3.0 3.0 4.0 4.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.0611801431292385 0.003892417122778628 0.009377869824763952 GO:0008094 DNA-dependent ATPase activity molecular_function 23.26005691219944 23.1077253445326 22.378465685664047 23.201738001878013 20.689955753808068 22.07342847149589 23.90332265106232 22.906601644466253 23.3738603996949 22.197134898292756 23.36900441326309 23.274104987364364 23.980483364245114 23.88419156653553 23.01147286202169 23.290666890803603 23.027279178432483 22.13059813822391 23.80815528650034 23.420099648144692 22.36112589005661 21.131764728263388 23.36091412225861 23.98570013856085 23.468227731392798 23.40693759913395 14.0 19.0 6.0 8.0 31.0 16.0 21.0 14.0 30.0 22.0 39.0 30.0 14.0 16.0 17.0 11.0 35.0 23.0 15.0 9.0 20.0 17.0 30.0 34.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.1523315676668382 0.4884223166225936 0.5675521891480417 GO:0008104 protein localization biological_process 27.469029286263947 27.99415371262947 27.52370328547684 28.42664137579516 27.35341511941204 26.436484205868613 27.259326919916553 27.716866029779354 27.15922285494016 27.741229053486858 27.642853924574442 28.136724972579398 27.8574270372908 28.347579175060787 27.410950713518066 27.788510760068196 26.80075073808225 27.085361543392853 27.41125144626439 28.72852631219713 27.00992345541005 27.722552311464106 27.57192199777048 27.90045272827033 28.127156472736722 28.516183839531326 192.0 174.0 181.0 155.0 187.0 166.0 184.0 247.0 238.0 271.0 257.0 196.0 212.0 205.0 178.0 208.0 290.0 262.0 189.0 204.0 207.0 209.0 254.0 325.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.5251244263655224 0.017926339076638688 0.03379466943753034 GO:0008134 transcription factor binding molecular_function 22.083101121456558 26.394957898665037 23.89022591857016 25.6476957897693 21.224888982569773 25.951602119641922 21.11544236700037 26.726414398471327 21.358052027408746 27.04608022579397 21.79199342826909 26.56345454842292 21.49835199914461 25.345706940061984 21.722860449402965 26.54944085384355 22.663950121746936 26.646466019525146 21.88995660894146 27.111527631514445 21.349368640335253 25.706878365364695 19.994393179823792 24.441736190190554 22.529540554006314 26.88799502720563 9.0 14.0 6.0 20.0 6.0 15.0 5.0 16.0 7.0 12.0 5.0 10.0 7.0 15.0 6.0 15.0 13.0 13.0 6.0 16.0 5.0 10.0 8.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -4.3118567772084795 3.225641456243767e-05 0.0005099643033035255 GO:0008135 translation factor activity, RNA binding molecular_function 29.728496261875826 29.22504325104476 29.459107354334485 28.539081068579158 28.93590527078325 29.215224582460753 29.562713414525994 29.07214716052712 29.642488998188945 29.589105416339997 29.523288727969184 29.619855102397786 29.656555974456055 28.74089689091465 29.65304569529012 29.02340570499135 29.20302168399308 29.08681836885973 30.484660353173524 29.46121453823833 30.138390567680297 29.16984461254133 30.169082236125888 28.927220117680093 29.611594624438034 29.748112927637482 153.0 144.0 130.0 189.0 118.0 202.0 164.0 207.0 163.0 204.0 144.0 169.0 170.0 205.0 124.0 211.0 189.0 219.0 178.0 189.0 145.0 190.0 166.0 219.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 0.5034530108310662 0.013042519940568903 0.025877686622941164 GO:0008144 drug binding molecular_function 30.317275407720427 30.54457699523365 29.600909335913148 30.0262216866848 29.62433416590441 30.556846040425693 30.22617097989623 30.772253227382627 30.552714928763447 30.42176238121669 30.74493980661027 30.593753146437827 30.481317891099142 30.370713022651127 30.469861707146336 30.73262173574779 30.06819575556567 30.549316437394282 30.90974743282639 30.821853183728532 29.85892259572759 30.38166408907372 30.240311736952826 30.588534487696833 30.393896384890127 30.55068089261005 659.0 782.0 667.0 965.0 1055.0 1219.0 1225.0 1119.0 1299.0 1150.0 1291.0 1002.0 1293.0 1180.0 954.0 1167.0 1665.0 1441.0 848.0 922.0 1178.0 1162.0 1218.0 1163.0 6.0 5.0 5.0 5.0 6.0 7.0 5.0 8.0 5.0 9.0 6.0 7.0 6.0 8.0 6.0 8.0 8.0 7.0 7.0 6.0 6.0 6.0 6.0 7.0 -0.2273015875132245 0.0832645166635504 0.12534875367444018 GO:0008150 biological_process biological_process 39.77537158533924 40.406255684873145 39.81594910141711 39.77479699747451 39.48349645232658 40.33038984054722 39.40799114974646 40.56203285151072 39.4290844148845 40.31716408831252 39.94177000274839 40.34777690006187 39.905613907962454 39.987721846159204 40.162433034200575 40.75519362129461 39.321391777628 40.80004014410794 40.35123906910293 40.60873712056458 39.70623710051723 40.266226796434786 39.6587599337032 40.513272031902154 39.73472861739595 40.286704356160335 444045.0 439118.0 432136.0 541742.0 495846.0 698554.0 563625.0 652019.0 585010.0 661749.0 627834.0 506212.0 629902.0 662980.0 488690.0 677520.0 776772.0 738560.0 567152.0 553497.0 594854.0 618690.0 598174.0 666667.0 16.0 14.0 15.0 17.0 16.0 15.0 15.0 15.0 16.0 14.0 18.0 15.0 15.0 17.0 15.0 16.0 15.0 16.0 17.0 14.0 14.0 17.0 14.0 15.0 -0.6308840995339011 0.0005320055051392492 0.0019244720881558927 GO:0008152 metabolic process biological_process 39.263832835514066 39.87391361109789 39.29092714819619 39.23688561743999 38.95755099143268 39.79833793479904 38.893962144568256 40.02695413432093 38.928758102462176 39.78106364061283 39.43363766822122 39.822271177693146 39.39461532850853 39.45573616606842 39.65004236243361 40.22327272680708 38.8101575716296 40.26615477252667 39.84258402155573 40.077484069332115 39.18931612222863 39.73354562109503 39.16429221290691 39.98557789377548 39.22323009910407 39.75280852816051 308415.0 304241.0 300195.0 377367.0 345021.0 485632.0 392760.0 453448.0 407513.0 460966.0 437533.0 351379.0 440460.0 461412.0 340521.0 471720.0 541575.0 513760.0 395071.0 385078.0 415585.0 429973.0 415580.0 462966.0 11.0 12.0 12.0 12.0 12.0 12.0 12.0 12.0 12.0 12.0 12.0 12.0 11.0 12.0 12.0 12.0 12.0 12.0 12.0 12.0 12.0 12.0 12.0 12.0 -0.6100807755838247 0.0005320055051392492 0.0019244720881558927 GO:0008168 methyltransferase activity molecular_function 26.75145008941892 27.06963675770832 26.68621957772727 26.64015400217431 26.80125913103464 26.95537133058195 26.0853269028034 27.039981888622155 26.21984546733773 27.12037036172423 27.18244634174401 27.21051028825956 27.20670906006421 27.228713226120053 26.90349921466771 27.186515438775093 25.39182326411705 26.77314983885035 26.95655375449945 27.455381737062467 26.984933693751874 26.43816063551257 27.07132434275291 27.405235051859627 26.583996180106396 27.049968144622717 134.0 213.0 110.0 248.0 153.0 276.0 176.0 251.0 232.0 271.0 273.0 242.0 157.0 329.0 136.0 309.0 240.0 261.0 167.0 180.0 156.0 360.0 284.0 238.0 8.0 9.0 9.0 11.0 11.0 10.0 14.0 9.0 14.0 9.0 14.0 13.0 11.0 12.0 11.0 12.0 12.0 10.0 10.0 12.0 10.0 11.0 12.0 13.0 -0.3181866682893997 0.04964722965745621 0.07872902492059129 GO:0008169 C-methyltransferase activity molecular_function 23.417530920345392 22.556444576466077 23.372796875397498 20.2235471462838 24.662633611271215 22.327061589352983 22.86909850003559 22.489718074200407 21.00143308482556 23.04432005062212 23.168231377235635 23.57148230038998 24.432249700793143 21.604390588710675 22.926671822884717 23.251036679244052 21.873209716975488 22.06993456431056 22.522488802247338 22.588881006034704 24.01046750642525 22.364231291531034 22.94735263892655 21.437081674788498 23.561394034066318 23.00324078852642 9.0 4.0 11.0 15.0 11.0 12.0 9.0 15.0 10.0 25.0 24.0 9.0 8.0 16.0 11.0 9.0 21.0 19.0 19.0 8.0 17.0 12.0 20.0 11.0 2.0 1.0 3.0 3.0 2.0 2.0 1.0 2.0 2.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 0.8610863438793146 0.0734883472918226 0.11239394291690516 GO:0008170 N-methyltransferase activity molecular_function 21.256218816874327 23.287736081183766 21.596801194227687 22.5017411317166 20.319171131086424 22.94686205483604 21.63298541925145 23.285963491490055 20.825027070205365 22.7577374848124 21.88355968793911 22.114718554564533 21.50125051547164 23.94728568781342 19.77705461318097 23.179428233169364 19.59230871761428 22.601923586675486 21.89221695252205 24.00193391997605 20.4881897376794 22.07309107956384 20.182564386741426 24.55088676142867 22.361156196753345 23.127858787726673 9.0 23.0 3.0 25.0 16.0 29.0 6.0 19.0 18.0 23.0 21.0 25.0 5.0 29.0 7.0 30.0 20.0 25.0 10.0 14.0 10.0 44.0 23.0 21.0 6.0 6.0 2.0 6.0 4.0 5.0 4.0 5.0 5.0 8.0 6.0 6.0 2.0 6.0 1.0 5.0 6.0 6.0 4.0 5.0 6.0 7.0 5.0 5.0 -2.0315172643094392 5.312128159411724e-05 0.0005099643033035255 GO:0008171 O-methyltransferase activity molecular_function 20.186488180299694 21.71897608575677 20.71567286239343 21.52116802549753 20.979724721121574 21.422980430751227 19.242285914059735 22.18751595931708 20.307748514302187 21.61463476354054 21.153138744255546 20.99791431196079 20.116797082607835 22.50133474894887 19.594251096040896 21.53378259549067 19.785087012136994 21.16646605172745 20.0173181758051 21.85313916269045 19.061621859336146 20.185708126748207 19.262073541074216 22.707108653164788 20.2067706868356 21.17348269075388 5.0 8.0 6.0 11.0 5.0 11.0 3.0 11.0 10.0 10.0 8.0 9.0 5.0 11.0 7.0 8.0 5.0 8.0 5.0 6.0 5.0 15.0 7.0 7.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 4.0 2.0 3.0 2.0 2.0 2.0 4.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 3.0 2.0 -1.5324879054570744 0.0001386794054294884 0.0007006959432226783 GO:0008173 RNA methyltransferase activity molecular_function 22.980217340180136 24.64463687485892 24.0296610807873 24.088305005030502 23.18972780403159 24.47672218828939 21.57037920487509 24.91171182076043 22.661352235734785 24.283858608913608 23.367548316837173 24.1152242598377 23.49273129080298 25.100352168946877 23.170987545629288 24.989137769461237 21.72511953963936 24.365371858376907 22.989567598528968 24.957238547238582 22.760802933413657 23.833498875139824 20.522921355112146 25.496064458070826 23.306261544896213 24.074489845782022 25.0 54.0 26.0 66.0 18.0 78.0 21.0 60.0 42.0 59.0 44.0 67.0 18.0 87.0 16.0 79.0 41.0 63.0 24.0 42.0 15.0 106.0 44.0 46.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.6644195346787853 4.146041132679973e-05 0.0005099643033035255 GO:0008175 tRNA methyltransferase activity molecular_function 20.62077767143863 23.10653982438048 21.843966462905588 22.96917127731967 20.92095382759953 22.46270511914328 19.58437572405579 23.73956189124673 21.613917458151374 23.160019001409964 21.58664022543365 21.8867141197544 20.074477824883047 23.896589700730985 19.22738138100141 23.19637168966264 19.407390775855472 23.254747687088408 18.687487965807065 23.29389158903715 17.630534149095595 21.959757499000073 16.713110045277855 23.641887889318024 21.657661618773126 22.08250169291032 8.0 14.0 8.0 16.0 4.0 25.0 11.0 23.0 11.0 12.0 9.0 27.0 4.0 24.0 4.0 27.0 3.0 20.0 2.0 15.0 1.0 35.0 11.0 12.0 3.0 3.0 4.0 3.0 2.0 4.0 3.0 3.0 4.0 3.0 4.0 4.0 4.0 3.0 1.0 3.0 1.0 3.0 NA 3.0 NA 4.0 3.0 3.0 -2.4857621529418488 3.225641456243767e-05 0.0005099643033035255 GO:0008177 succinate dehydrogenase (ubiquinone) activity molecular_function 25.21719190955493 23.669168722761984 23.986596936435784 15.679442987093699 NA NA 25.295073095110606 22.073312234229803 23.196404165080942 23.769641797183503 25.56239688683363 24.989978426003557 26.09814815393296 23.25978887064621 24.138547629992857 23.319577732313128 23.94374512306441 23.751572013407717 25.9224445287113 23.33785104829925 25.70710330152155 23.98540164165875 25.676440846796023 22.71281895318338 25.0050965292169 24.6276579636745 6.0 1.0 NA NA 11.0 3.0 9.0 3.0 13.0 6.0 7.0 1.0 3.0 3.0 4.0 3.0 20.0 7.0 6.0 2.0 7.0 1.0 6.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.5480231867929461 0.002810319919875129 0.007231503628874559 GO:0008184 glycogen phosphorylase activity molecular_function 21.035262754768876 23.850028513922624 22.07107798429237 23.244134416639284 21.435701065383665 20.898494561305593 18.669589196925493 23.893228483386217 19.326446317062093 24.578484285947194 20.05175023942901 24.002813585037607 19.64268085394421 22.19257906806337 22.61645960202477 23.84752058986389 21.67485900907149 24.16403707389443 20.984877444450497 24.304406256212662 20.390865531650075 22.722257602295908 19.882750513690453 24.957536856641077 20.38666441936727 23.655280245594266 7.0 9.0 2.0 2.0 2.0 9.0 2.0 12.0 4.0 9.0 2.0 3.0 5.0 10.0 5.0 15.0 6.0 8.0 3.0 5.0 2.0 10.0 3.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.8147657591537474 0.0001386794054294884 0.0007006959432226783 GO:0008194 UDP-glycosyltransferase activity molecular_function 22.268233614446387 22.74504213914657 23.435291281760225 21.804309042518906 22.454029283928627 22.41019778267932 21.40227531857402 22.284244132396708 23.04185274809164 22.340799553559574 22.346741741054807 22.433510471824714 22.321226776859547 22.491346493252244 21.009185579896574 24.071520760389234 20.793809022517824 23.20001888376054 21.626539836543003 21.614810643968248 22.24829884471282 22.73368501348689 22.241671648708927 23.252061726253988 22.081769847678128 22.442180837925054 8.0 15.0 9.0 28.0 12.0 12.0 19.0 13.0 13.0 12.0 10.0 12.0 6.0 38.0 10.0 31.0 16.0 14.0 12.0 17.0 12.0 32.0 16.0 12.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 1.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 2.0 2.0 2.0 3.0 -0.4768085247001821 0.0734883472918226 0.11239394291690516 GO:0008199 ferric iron binding molecular_function 25.235201049655394 26.116845327984862 22.644776457783546 27.025523466351363 26.290722119021783 26.440561181126327 26.022732718033794 24.67152644828649 24.545046169963488 25.54237168747551 22.23244357369638 22.116409803784013 26.95889136983129 26.673201268883357 25.07818154273459 26.506441878330932 24.286422598787656 25.18754635236632 25.45007287090927 27.235110306787696 24.819634563971128 26.667451721602106 24.28785768115971 23.35623585979761 22.37967668103304 25.562765217436628 1.0 1.0 2.0 1.0 4.0 3.0 2.0 3.0 2.0 1.0 2.0 2.0 1.0 1.0 3.0 3.0 3.0 4.0 1.0 3.0 3.0 2.0 3.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8816442783294676 0.0734883472918226 0.11239394291690516 GO:0008235 metalloexopeptidase activity molecular_function 23.717557748871297 22.99383087719565 24.253691861254683 21.993198442742358 23.22215348327909 23.818165070094285 23.461469175133434 22.695832335597405 24.743336650199257 22.048050266228266 24.60236357494825 22.877000417120037 23.918399880456835 21.93839726889112 22.376147778226656 23.877338896502103 23.161783530751638 23.49511112613481 23.462680095253024 23.244966802293373 22.15039689197952 22.497537943855885 23.416915889340626 22.95835534468861 23.57976565536513 22.773727603885533 19.0 10.0 13.0 15.0 16.0 16.0 26.0 12.0 24.0 20.0 23.0 10.0 14.0 23.0 16.0 14.0 25.0 19.0 13.0 14.0 21.0 13.0 17.0 20.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 0.7237268716756482 0.043308142810791976 0.0706517153305469 GO:0008236 serine-type peptidase activity molecular_function 25.46782097750868 24.72994113569069 24.435013827159253 23.46452520310586 24.944819930361557 24.434206890791483 24.55221271037825 23.91125852840105 25.9473103914657 23.693165853816733 25.39636917991236 24.25222997712372 25.48259631283161 24.59934943332907 25.834101450264196 25.306283785788132 24.73957736608901 25.779369607202376 26.62939706362082 25.116931184959768 24.25910863051493 23.05809650332897 24.94225978651163 25.859147211279225 26.20935347406944 24.243418443683574 33.0 20.0 41.0 38.0 30.0 32.0 38.0 35.0 41.0 39.0 49.0 44.0 61.0 38.0 31.0 73.0 90.0 61.0 27.0 19.0 47.0 74.0 39.0 50.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 0.737879841817989 0.024343383653741054 0.04309296851045225 GO:0008237 metallopeptidase activity molecular_function 26.10823319590664 26.790503686045927 26.191849178542466 26.00760337684489 25.267538137795373 26.663777149197283 25.518034174271307 27.20363120942171 26.49308594491543 26.63263894570441 26.19933905509933 26.92438138866323 25.98799199661233 27.064920860192103 25.95529789578298 26.865608742671036 25.44211002265947 26.40547499835113 26.358022559411047 26.9657969993894 26.165628730179915 26.698278234859963 27.007080218946122 26.954502426508807 25.79160818277005 26.733671689020074 72.0 82.0 72.0 104.0 71.0 139.0 89.0 128.0 86.0 111.0 85.0 100.0 98.0 141.0 68.0 136.0 106.0 136.0 70.0 130.0 77.0 109.0 84.0 131.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.6822704901392882 0.0012242832644312096 0.0037265988146589013 GO:0008238 exopeptidase activity molecular_function 26.15967161203156 27.50460993172028 26.981481624984887 26.88356361803547 26.54531581406071 27.184223230460137 25.879715883505373 27.11796760855216 26.192299422534195 26.87036202923539 26.509731723855857 27.537584848721593 26.449139511480322 27.02149180438797 25.717869579520954 28.09926665324678 25.87976139940628 28.609678529564835 26.211299254974648 27.33188920490708 24.443790373458878 26.827093717952305 25.1957669049762 28.192295138781546 26.38527648375896 26.80772250809185 102.0 117.0 111.0 196.0 77.0 153.0 101.0 146.0 110.0 161.0 113.0 100.0 85.0 209.0 71.0 198.0 134.0 156.0 72.0 139.0 85.0 180.0 111.0 158.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 7.0 6.0 5.0 5.0 6.0 5.0 6.0 4.0 -1.3449383196887226 8.637667594722788e-05 0.0006159890947550879 GO:0008253 5'-nucleotidase activity molecular_function 20.864269653243326 20.90142021803754 21.82909588074341 19.682920149986405 15.89415578986072 NA 18.587549360775547 17.49778214500195 19.973826716296987 20.465976473463908 21.746278019510328 22.72168372568517 21.60447112694442 21.287832702097003 19.65118014808456 16.82382980728827 17.57126215676443 15.298803269981216 21.51267921370816 21.071690943169767 21.611304849528032 16.108987284243323 21.470868598882493 NA 19.729129971762873 22.310975321316448 12.0 2.0 1.0 NA 1.0 2.0 4.0 3.0 5.0 8.0 7.0 6.0 4.0 1.0 1.0 1.0 8.0 5.0 8.0 1.0 6.0 NA 5.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.037150564794213636 0.46825664615340634 0.5502676971746244 GO:0008270 zinc ion binding molecular_function 27.6750163419416 28.522550278365873 27.95819439275989 27.852981007011465 28.863306791660108 28.63351017674263 26.99124370822728 28.4827600668605 26.730982453877306 27.97853990450139 27.348185417928505 28.70729007192865 27.504694352223506 28.522069660809173 28.41713766268332 29.041443259009643 26.694454726384958 28.690248316758126 27.023885528662078 28.363408231621516 28.043932707521343 28.418246940594358 27.363513568259343 28.82796906749222 27.28416176221458 28.336014457640122 208.0 210.0 238.0 274.0 158.0 295.0 175.0 287.0 219.0 276.0 258.0 262.0 205.0 318.0 152.0 311.0 247.0 298.0 228.0 266.0 194.0 279.0 230.0 291.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8475339364242735 0.0018227351663913985 0.005134928866041682 GO:0008276 protein methyltransferase activity molecular_function 20.04147941566547 21.468984046980392 19.745675183381266 20.342122587065283 20.16645258700982 21.405310321131747 20.26143143446525 21.604670964123148 19.850389806794414 21.15436508427677 19.628914066538588 20.14868146541996 20.08219447039513 20.718129722171575 20.796836523811105 22.15304105074311 19.657669868751977 20.725840420171 20.45348248792696 23.3540668785834 20.25165243836398 21.261973199722913 19.763581947706076 20.338779378846453 19.063625360345565 20.370085800533182 3.0 4.0 3.0 7.0 5.0 9.0 5.0 7.0 6.0 6.0 7.0 6.0 4.0 9.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 7.0 5.0 6.0 NA NA NA NA 1.0 NA 1.0 NA 1.0 1.0 1.0 1.0 NA NA 1.0 NA 1.0 1.0 NA NA 2.0 NA NA NA -1.4275046313149211 0.0006583371695572323 0.0022696264851033866 GO:0008289 lipid binding molecular_function 23.799998809498877 22.367224766661955 NA 22.79579879854928 20.167825768762697 22.08229537430088 23.728979107719113 22.3417057781783 24.471034348427377 22.02017778008944 23.5847256093334 21.498006099920907 23.361426444938733 22.65928659082541 23.09036073480531 21.447219987372264 24.040457445827556 21.301294231299188 22.78941550788857 23.900823156194736 NA 22.219247549699023 22.72062926521924 22.38306781855352 25.391438379287486 21.302384476187864 NA 3.0 1.0 5.0 19.0 3.0 14.0 2.0 22.0 1.0 21.0 4.0 15.0 4.0 24.0 5.0 10.0 13.0 NA 2.0 22.0 3.0 30.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA NA 1.4327740428369218 0.008351423441556883 0.017785966646865173 GO:0008312 7S RNA binding molecular_function 21.49956808915745 23.46367378003324 21.530034332999097 22.784948900459685 21.687730119088855 23.33933692288361 20.809127724657888 23.688643739716092 21.213743377802825 22.783305200969853 21.2961495474887 22.88659807411636 22.631026891906576 23.963807432354173 20.931528813068198 23.840157221980945 20.491029106162355 22.985916225891447 21.093662140801122 23.609596259118014 21.14845646997046 23.29876121651011 22.005910909897953 23.99248756512537 21.773798083484802 23.63103577177643 7.0 5.0 10.0 16.0 8.0 17.0 6.0 16.0 9.0 15.0 16.0 13.0 7.0 17.0 7.0 18.0 10.0 17.0 9.0 10.0 10.0 14.0 10.0 21.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.9641056908757903 3.225641456243767e-05 0.0005099643033035255 GO:0008324 cation transmembrane transporter activity molecular_function 28.63452247318111 29.606307221717557 28.41071628449821 28.98980320219421 28.126630665868984 29.425913155633697 28.24674131230885 29.546644834160514 28.512206342729613 29.50842177980477 28.719269765129066 29.653715863284532 28.785445053761787 29.33403806642614 28.411878980441198 30.035576070460557 28.490349764050695 29.76176712415381 29.10517205843817 29.673842094018077 29.08455816025884 29.426398757701346 28.67008405542252 29.848193720679106 28.70215504652645 29.79081095833289 305.0 327.0 286.0 404.0 278.0 442.0 409.0 468.0 362.0 479.0 400.0 377.0 400.0 501.0 301.0 397.0 357.0 493.0 362.0 439.0 368.0 412.0 380.0 553.0 3.0 3.0 3.0 3.0 3.0 3.0 5.0 3.0 5.0 3.0 7.0 4.0 4.0 3.0 6.0 3.0 5.0 4.0 5.0 3.0 5.0 3.0 6.0 5.0 -0.9717847485364466 5.312128159411724e-05 0.0005099643033035255 GO:0008360 regulation of cell shape biological_process 24.687884577215556 26.15261662920623 25.38774215165689 25.65914226803532 24.34462893685153 25.23753172098709 24.27687743897656 26.434919134319593 24.752791519149017 26.012076943380777 24.9338554872076 26.393856434749107 24.962788631062303 26.545217349191297 24.399496944876148 26.38484172548525 24.550416046091343 26.0695546336282 24.446457524401346 26.09688943556377 23.862297956104808 25.56884839982635 24.703474030449968 26.974539970005864 25.00347442513554 25.475718757803932 52.0 84.0 49.0 82.0 57.0 133.0 54.0 139.0 74.0 137.0 87.0 114.0 63.0 131.0 60.0 140.0 86.0 139.0 55.0 96.0 74.0 156.0 78.0 109.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.4647320519906728 4.146041132679973e-05 0.0005099643033035255 GO:0008374 O-acyltransferase activity molecular_function 21.260498686087367 20.268610370485725 18.095654382436077 NA 20.77159425173552 22.23614319800464 20.566504881537746 20.94854819167113 18.428561493403357 17.14374738182182 21.63786798275328 18.47415324871892 23.391733332139346 21.00771808076613 17.87922011571349 19.89365257003697 19.491098628102755 19.442345735396007 20.89907960953821 NA 21.482416525347112 19.655039886241614 21.940455376945 17.823783170933872 20.94105732293963 18.22479562135427 2.0 NA 5.0 6.0 6.0 13.0 3.0 2.0 9.0 4.0 14.0 8.0 2.0 2.0 4.0 3.0 12.0 NA 6.0 3.0 9.0 3.0 8.0 4.0 2.0 NA 2.0 1.0 3.0 2.0 3.0 2.0 5.0 4.0 5.0 3.0 1.0 1.0 3.0 3.0 4.0 NA 2.0 2.0 4.0 2.0 5.0 4.0 0.991888315601642 0.26231050622385277 0.33644759688321507 GO:0008375 acetylglucosaminyltransferase activity molecular_function 20.982290946777663 21.511796886802177 NA 21.094474714194746 17.931771518517298 21.68127851026649 20.81715252943116 19.823855753818787 22.738669011401612 20.94220592809853 21.121322598562426 19.11476550669465 18.33331697951265 21.404808324959973 NA 23.23209191644937 19.982631571454547 21.5236015840284 20.445524955018282 20.54463745952318 19.425493731618033 20.938646584471297 21.79528516265424 22.635761449104194 21.069318323310128 20.028263615590085 NA 10.0 4.0 20.0 6.0 6.0 16.0 8.0 6.0 4.0 2.0 6.0 NA 24.0 4.0 12.0 6.0 10.0 6.0 10.0 8.0 22.0 8.0 6.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.5295059400245137 0.29142131954205963 0.36699677778858775 GO:0008408 3'-5' exonuclease activity molecular_function 21.45728729240454 22.88190128250407 21.6569626275302 22.68137578088511 22.28606825480403 23.047782449838124 20.625406677416954 22.034222813893066 20.301472342839748 21.980947107871653 20.566805376543588 22.767055889559717 21.967482098078605 23.571826434939126 19.328151991592428 22.54722627444643 20.705926430643267 22.687063666434675 23.201078574023185 22.573054963581377 21.326307735155357 22.346983564726425 20.10701393069925 23.967240250531145 20.776634041472573 23.011554439724712 12.0 21.0 12.0 22.0 7.0 19.0 7.0 11.0 10.0 24.0 20.0 41.0 8.0 26.0 9.0 21.0 26.0 20.0 7.0 7.0 7.0 36.0 9.0 21.0 1.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 NA 1.0 1.0 2.0 2.0 -1.4246139900995303 0.0005320055051392492 0.0019244720881558927 GO:0008443 phosphofructokinase activity molecular_function 22.948960319782163 24.90723289493052 23.37968464176853 24.523372489694772 23.02557842984536 24.32044642453115 22.463874601432945 25.42438988888701 23.036689557702946 24.983318610242485 22.933400867621607 25.270734886850015 23.33118968702765 24.879241937290892 22.888457491426376 24.83656670822496 23.33046597919581 24.7395709926384 22.720369950451712 24.887819155547408 21.37409254044939 24.343808341337944 23.160136965482938 25.216332135932582 22.82766810519829 25.00542470389764 7.0 13.0 9.0 13.0 11.0 19.0 15.0 17.0 16.0 18.0 12.0 11.0 11.0 16.0 14.0 21.0 11.0 20.0 8.0 16.0 11.0 17.0 10.0 19.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 -1.9582725751483565 3.225641456243767e-05 0.0005099643033035255 GO:0008448 N-acetylglucosamine-6-phosphate deacetylase activity molecular_function 21.1579984833457 22.794076256769465 20.411370417368158 22.293687480806803 21.654565459325575 23.569299876802702 21.056727719153 23.999478455863844 19.697583813409945 21.896105599815264 20.031659358091083 21.29779219808021 20.57563470105077 22.50965777115955 21.996570149232696 22.349831682017207 21.76410244488369 22.4722399512075 22.766033287701802 22.798692649075168 18.98967541903296 23.13911018464603 18.57324875271564 22.882256138609947 20.878122705872592 22.262920617527968 5.0 7.0 7.0 13.0 5.0 16.0 3.0 9.0 4.0 10.0 5.0 9.0 10.0 10.0 7.0 11.0 9.0 9.0 2.0 14.0 1.0 11.0 6.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.6360777734237644 0.00042856814449695465 0.0016457016748683058 GO:0008483 transaminase activity molecular_function 25.840987878127322 26.034795129059855 24.036139132970728 24.721211785886922 24.502556425420288 26.04744000817293 25.11759858063456 26.26981467797775 26.864672384696345 26.374364705507865 25.72737074502566 25.998344124819784 25.63634539769381 25.71453666189385 27.26561043410005 26.1064265419612 25.416509699950836 26.075917141197014 25.709060417475385 26.07395714680869 25.319706483775484 25.554198504290767 25.48366803704977 26.43209746390191 25.9359146725508 26.332912239563427 46.0 46.0 46.0 58.0 69.0 105.0 78.0 102.0 99.0 105.0 97.0 73.0 104.0 108.0 70.0 120.0 117.0 114.0 83.0 88.0 97.0 100.0 101.0 104.0 5.0 3.0 7.0 6.0 8.0 7.0 6.0 7.0 10.0 10.0 8.0 5.0 6.0 10.0 6.0 7.0 11.0 6.0 9.0 6.0 9.0 6.0 10.0 6.0 -0.19380725093253304 0.04964722965745621 0.07872902492059129 GO:0008509 anion transmembrane transporter activity molecular_function 23.454976318739103 26.267485916043853 23.331093925333057 25.83698981351241 23.00628961914976 25.547145026360266 22.63050740208695 26.346182922647696 23.310869095917273 25.850345520210475 24.18278124702725 26.460450234332967 24.234009606876306 26.8290285422335 23.82293690565185 26.59143122075798 23.007638368646337 26.214299660791912 23.630025933356503 26.043379827066914 22.47010518911262 25.202725437688688 22.656930672048716 27.301925001223392 23.80493550897476 25.59876157155221 42.0 120.0 30.0 109.0 17.0 160.0 23.0 106.0 30.0 136.0 55.0 151.0 41.0 187.0 33.0 146.0 38.0 129.0 20.0 117.0 25.0 177.0 37.0 107.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 -2.81250959730475 3.225641456243767e-05 0.0005099643033035255 GO:0008514 organic anion transmembrane transporter activity molecular_function 23.246173744775074 26.0720104683752 22.674787904104747 25.600578830552703 21.769613224481454 24.979165945750562 22.63050740208695 26.117292510895496 23.270635366607 25.7341816904424 24.18278124702725 26.37423977872653 24.166207470196053 26.67180671128726 23.656549909214768 26.45404655840176 22.880521712150607 26.0847144294821 23.050520505502767 25.701334696446036 22.25230944960649 24.859130599631968 22.656930672048716 27.13392652543156 23.67552196254076 25.41387112457363 25.0 91.0 16.0 77.0 17.0 132.0 20.0 92.0 30.0 110.0 47.0 103.0 35.0 153.0 27.0 120.0 15.0 99.0 13.0 103.0 25.0 147.0 29.0 91.0 2.0 3.0 1.0 1.0 2.0 1.0 1.0 1.0 3.0 3.0 1.0 2.0 2.0 2.0 1.0 2.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 -2.8258367236001263 3.225641456243767e-05 0.0005099643033035255 GO:0008519 ammonium transmembrane transporter activity molecular_function 22.964650170689488 21.80973021374007 22.028300891928872 21.20241230460964 22.727021729737267 22.398109061738683 22.003061385593373 21.24974847367595 23.802051151399976 21.04018907226588 22.574263493082427 22.58950217864696 23.453043744863553 22.07988061170795 22.60401579977872 22.423175871851967 23.359563219054323 19.889390551612788 22.704836861638487 21.91416185764761 23.124054135374546 21.703749945255915 22.951546191578327 22.093898561176925 23.13651848438777 21.157433706457226 9.0 6.0 10.0 10.0 8.0 8.0 25.0 8.0 16.0 14.0 19.0 14.0 17.0 5.0 15.0 2.0 12.0 13.0 10.0 8.0 22.0 8.0 16.0 6.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.154919956949417 0.00042856814449695465 0.0016457016748683058 GO:0008544 epidermis development biological_process 20.528158809528843 20.004410656906053 19.151519743716268 19.65686904590007 19.086236046215614 20.69542264506213 NA 19.940603404863968 19.27125512533839 NA 22.634889640015068 19.62429781255448 20.61034575963044 20.30371049874706 19.726208762053695 20.539439978645113 21.01400486748545 18.963166185639288 19.014510884390265 19.60781951431197 18.00603587084595 NA 21.41360493522225 19.92960630029664 17.43245593157638 NA 2.0 3.0 2.0 2.0 NA 3.0 3.0 NA 5.0 3.0 3.0 2.0 2.0 4.0 4.0 3.0 2.0 2.0 1.0 NA 3.0 2.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.5237481526227903 0.6214268342178599 0.6911306926646184 GO:0008565 protein transporter activity molecular_function 21.549264171721397 20.51401315212119 20.022196575267728 NA 16.47524409615321 21.429909813477718 21.197298730194884 15.19266807537262 20.02654087392661 19.157932928507066 21.771485738704847 21.037246978088746 22.78224344485632 NA 20.487347495417296 20.367464025193605 21.339456179850878 19.75058203029133 21.88928717959756 17.804261347597848 21.812812202071363 NA 21.818567058997253 21.72126299235984 22.51986924534936 20.899282720512485 6.0 NA 1.0 11.0 5.0 2.0 6.0 4.0 6.0 5.0 9.0 NA 7.0 8.0 7.0 10.0 7.0 3.0 5.0 NA 6.0 5.0 8.0 5.0 1.0 NA 1.0 1.0 2.0 1.0 1.0 1.0 2.0 1.0 2.0 NA 2.0 1.0 2.0 1.0 2.0 2.0 1.0 NA 2.0 2.0 2.0 1.0 1.0352510196002065 0.04660488845237353 0.07593067988062946 GO:0008610 lipid biosynthetic process biological_process 28.43936838530369 28.294314159311018 27.79036010684073 25.769280611625145 26.07121010714981 26.56563734501865 28.0230504286977 28.30679547408395 28.803076617880553 29.29628221458463 28.49783419242028 28.947650069286762 28.92058930030832 28.022965067420074 28.5298829702022 27.708469932459032 28.222165709766955 28.378613049764052 28.93347089489157 28.532187237177816 28.56637446643278 27.812365970103308 28.90547491027433 28.277825951881127 28.268674485733555 28.880661455667486 138.0 64.0 75.0 115.0 196.0 185.0 281.0 212.0 233.0 195.0 253.0 150.0 215.0 165.0 206.0 205.0 309.0 250.0 184.0 166.0 250.0 171.0 235.0 200.0 6.0 6.0 6.0 6.0 7.0 6.0 6.0 7.0 6.0 6.0 6.0 6.0 6.0 7.0 8.0 7.0 6.0 6.0 6.0 7.0 6.0 6.0 8.0 7.0 0.14505422599267348 0.5253727863737021 0.6008633207515945 GO:0008615 pyridoxine biosynthetic process biological_process 20.51952249728312 20.76912302112726 19.006307529898237 17.215113136515008 NA 20.007467572097344 20.09686683899632 NA NA 17.18588019631241 20.463840874585323 20.17708590864501 21.37368643106037 NA 18.53334418928031 22.40385225804892 19.414532653229667 22.52774163573607 21.413480302797247 15.307756453769901 20.699585291479554 19.812397036392483 20.806625665765665 21.05998194658375 20.78863866262633 19.16036122767382 1.0 1.0 NA 4.0 4.0 NA NA 1.0 7.0 3.0 6.0 NA 2.0 9.0 4.0 8.0 10.0 1.0 6.0 3.0 6.0 9.0 7.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.24960052384414055 0.4496917979688909 0.5347630423627702 GO:0008616 queuosine biosynthetic process biological_process 20.53703136956376 22.10829487857742 21.623259348451377 22.052143350329004 20.745945278934933 22.455922898958544 20.049329772285322 22.173363786627068 18.64147429853807 21.017841952007533 20.910705757090376 21.641172383284935 20.153867831371244 22.40717768102937 18.73177488353053 22.51873374703845 19.680850472942094 21.716794135039187 20.400082049918524 22.059030573062905 21.116145000891446 21.95005861425148 21.393296090223085 22.76205452148608 19.857591755983886 21.729580284093547 4.0 12.0 7.0 10.0 6.0 14.0 4.0 9.0 8.0 14.0 8.0 11.0 4.0 13.0 5.0 14.0 9.0 10.0 8.0 11.0 7.0 19.0 6.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.5712635090136615 6.784570247173055e-05 0.0005498145239267514 GO:0008649 rRNA methyltransferase activity molecular_function 22.421183721555682 23.871885138547988 23.64110514861514 22.78449816929973 22.66893979557345 23.84264799626508 20.68320782200653 23.84580269432625 20.940949556169862 23.235543801748122 22.607848899862965 23.595705798563053 23.128563214192905 24.13689535353794 23.074039002028517 24.3915693759118 20.61158299535655 23.251515523357305 22.413201504050285 24.292772339651908 22.71901174068294 23.210097949094468 19.961437618631333 24.92239678227172 22.082960232264327 23.495467246987943 16.0 30.0 13.0 43.0 11.0 41.0 7.0 32.0 27.0 40.0 29.0 30.0 14.0 53.0 10.0 42.0 31.0 35.0 22.0 23.0 12.0 61.0 27.0 27.0 3.0 3.0 2.0 5.0 5.0 4.0 3.0 4.0 4.0 4.0 5.0 3.0 2.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 3.0 4.0 4.0 3.0 -1.450701416992306 0.00021985068263840352 0.0009941074345388681 GO:0008652 cellular amino acid biosynthetic process biological_process 27.980186369347265 29.582475277245322 28.18917724311154 28.47630343506103 27.799412330831576 29.18404841301096 27.88913552701014 29.26741345173336 27.547032316755104 29.298518072085407 28.09121496582748 29.930411353394128 28.312479343737397 29.30644706780075 28.34551721552895 30.17213127581952 27.63533350508545 30.29891741056205 28.29872225070785 29.34449051691732 27.67476548062665 28.932228773931733 27.835237278554946 30.255624559571014 27.839605460567732 29.30559721377432 357.0 467.0 380.0 590.0 279.0 754.0 273.0 778.0 396.0 802.0 489.0 611.0 437.0 883.0 304.0 969.0 516.0 661.0 456.0 669.0 467.0 859.0 387.0 773.0 5.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 5.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 -1.602288907898057 3.225641456243767e-05 0.0005099643033035255 GO:0008654 phospholipid biosynthetic process biological_process 27.041736001647312 27.100706597133108 26.490365873057733 22.429921447575026 22.73226122400285 24.473925896424408 26.58109703206436 27.150776641501132 27.66305908334619 28.329564483309593 26.954600856606746 27.786739036483702 27.509081273966988 26.51200490789445 27.434771541235147 26.355776577601162 26.79390783707875 27.189803333813877 27.26830422636171 27.32535061347588 27.136158764011817 26.59833719093071 27.64730882512943 27.01154134223681 26.652824771840248 27.841426336526524 60.0 15.0 10.0 29.0 76.0 81.0 126.0 93.0 99.0 86.0 111.0 65.0 88.0 63.0 87.0 84.0 116.0 104.0 80.0 66.0 112.0 78.0 98.0 84.0 4.0 2.0 3.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 5.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 -0.058970595485796196 0.9539596927720386 0.9577970205788449 GO:0008655 pyrimidine-containing compound salvage biological_process 25.883272814694482 26.367157759612585 25.792477127298657 25.36004572492267 25.082480210779448 25.876315104496108 25.476651291965783 26.292186528572067 25.56433694113416 26.66919546427209 26.42650305468166 26.818495191139395 26.071964126235947 26.28337286485929 24.79308780005005 26.08236981891665 25.59851689672219 26.107645939774 26.36198239830487 26.289174896290806 26.81489115692068 26.28058541702454 25.55099207852512 27.081538987797106 25.806504264994448 26.51975221682855 45.0 35.0 28.0 43.0 52.0 41.0 60.0 52.0 52.0 67.0 57.0 32.0 53.0 41.0 57.0 57.0 73.0 69.0 52.0 37.0 65.0 64.0 63.0 53.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.48388494491810263 0.02824036873330045 0.04901805310036017 GO:0008658 penicillin binding molecular_function 21.035209148930786 22.030597039872408 19.764376192462077 21.64318049691723 18.224497757349933 21.79371343193319 21.444186289565106 21.11707202914804 19.139448543159176 22.283610421381297 19.131775785002986 21.35090881998889 22.84401927315135 23.06894956356534 22.08064221102576 22.385989889175182 20.70169767724044 22.613273470457074 14.217105208295793 22.160350505998224 20.65647443499619 19.755443083051624 21.84365685500326 21.983280737915287 20.497473585838282 21.94251744840316 4.0 8.0 1.0 4.0 3.0 10.0 2.0 12.0 3.0 10.0 12.0 18.0 5.0 11.0 5.0 7.0 1.0 7.0 7.0 6.0 9.0 14.0 7.0 15.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9953878909416218 0.01531382171343201 0.02967647437634029 GO:0008662 1-phosphofructokinase activity molecular_function 20.670227159751857 23.692037477421266 21.466180495472837 22.97691834297965 22.710836839614377 22.014921816002346 19.7353556595286 23.789422926169753 NA 24.175661339046695 20.257914842335047 24.43559912949855 20.397898389530674 23.47361847326777 17.255730441735665 23.45692862585257 19.777554403082398 23.778285907309733 19.131131716436247 23.573548355698748 19.8502725471033 23.027814171714862 17.77020741905204 24.54616406524473 21.124573434711348 23.379405473915767 5.0 10.0 6.0 10.0 2.0 15.0 NA 14.0 3.0 13.0 4.0 7.0 1.0 11.0 3.0 17.0 3.0 11.0 2.0 12.0 2.0 13.0 4.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.0218103176694093 6.321587792507137e-05 0.0005498145239267514 GO:0008712 ADP-glyceromanno-heptose 6-epimerase activity molecular_function 21.174476300172802 20.055242244305266 18.34882761047047 NA NA NA 21.448312680365305 19.889659984608517 21.136195216624127 21.35439728160557 21.461453287906508 20.9319969812917 21.722609234612552 19.165623434127053 20.49145904275132 17.337316314034222 21.341344392842206 19.23106115022748 21.239300289944122 19.392724472524506 19.982630101636204 NA 21.402027974185653 19.026237331402136 21.84695652847815 20.57424982742597 2.0 NA NA NA 4.0 2.0 4.0 6.0 4.0 7.0 6.0 3.0 4.0 1.0 6.0 1.0 8.0 4.0 3.0 NA 7.0 3.0 6.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.1192340558675369 0.013543601483181442 0.026786711015864405 GO:0008716 D-alanine-D-alanine ligase activity molecular_function 21.28690379591737 21.124885014343995 18.896008960210555 19.48442561224659 17.184515654398762 20.915764715968553 20.508695042356955 21.270845868755774 22.303598444612227 21.95367895237349 21.91600782176637 21.937772001735787 21.447047696623237 20.78907054464665 20.67574530563708 19.68729458234165 21.710545059550704 18.11097228072103 21.53688801769536 22.400135602463745 20.169252618198083 19.662543271458773 20.97786926995037 21.33590442719901 22.306639695317717 21.04883620245901 1.0 1.0 1.0 4.0 4.0 3.0 7.0 7.0 6.0 7.0 9.0 3.0 5.0 4.0 5.0 2.0 10.0 10.0 4.0 2.0 7.0 4.0 9.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.16201878157337646 0.7728299926844475 0.8146045868836069 GO:0008730 L(+)-tartrate dehydratase activity molecular_function 26.862071084371014 27.42467335063592 26.15976899769131 NA NA NA 25.79304176970181 27.96628398618453 25.33251394130341 28.57961822701442 25.756352174362725 27.341918114320816 27.08068654003869 25.72977235715677 27.029192192951488 26.629950490243672 27.794982709815336 27.653265242941128 27.107970073697658 26.53805692124619 27.619892069207893 26.860287522899704 27.13329347187501 24.9504815648155 26.573234512249627 28.36523866342233 13.0 NA NA NA 10.0 23.0 13.0 20.0 12.0 15.0 12.0 13.0 17.0 16.0 15.0 20.0 12.0 15.0 20.0 18.0 18.0 14.0 16.0 20.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5626022662649071 0.3981027163512083 0.4809604937137541 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity molecular_function 24.274268799443952 24.908375441111325 24.22082290906701 24.10850778810709 24.86694951046061 25.117380911246748 23.678235157468663 24.948488533208675 23.54984042163785 25.222687626098967 24.36326451298203 24.799366847787446 25.11769598258265 24.937773638912763 23.72050865960863 24.825665434748554 23.3916870886262 24.346550735029894 24.32088662050666 24.97480698707749 24.54769146439109 23.94956832949177 23.68129082687473 25.637996100323186 24.62527941700237 25.181887697617945 29.0 50.0 17.0 58.0 38.0 67.0 41.0 65.0 52.0 71.0 70.0 53.0 32.0 77.0 38.0 64.0 71.0 64.0 49.0 36.0 46.0 94.0 72.0 61.0 10.0 6.0 5.0 5.0 7.0 8.0 8.0 8.0 8.0 9.0 9.0 8.0 7.0 7.0 8.0 8.0 9.0 8.0 6.0 7.0 6.0 11.0 7.0 9.0 -0.6341066416673726 0.009374768459434895 0.01937038251220985 GO:0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity molecular_function 22.36686324579106 21.559892042249835 20.66326236875165 17.24843995428001 19.40801527236132 21.15646466984448 22.19952787408377 21.951369660426792 22.542612870200426 22.58540608201225 23.34099766381581 22.05622261966271 23.31430070145427 20.767537574803647 22.025117732500075 21.368051981194924 22.02437596916504 20.77982299922447 22.48861097205693 21.44183528838533 21.448690144358608 19.885386294002245 22.737023949734965 22.20754666987909 22.58586337638501 22.23704819252532 5.0 2.0 3.0 7.0 13.0 15.0 13.0 20.0 17.0 16.0 18.0 12.0 15.0 8.0 11.0 10.0 17.0 19.0 10.0 5.0 16.0 16.0 15.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.8069712035412238 0.05674681648938142 0.08919398863822169 GO:0008763 UDP-N-acetylmuramate-L-alanine ligase activity molecular_function 21.640322961629405 22.102569422154552 18.780474101282508 19.3890169795732 17.855567151133915 21.991523675234642 21.643955200637787 22.033170339057712 22.509484542545447 21.528369232934928 21.927348028110604 22.32596925628873 21.969416689125765 20.696460689776185 21.48169896316935 22.522064394472203 22.000546776365923 22.542791083727327 21.530140783605862 21.896550134459506 21.11269083305087 21.361706369189502 22.19938920100961 23.51481313805883 21.91680849543409 21.999483145607773 2.0 2.0 1.0 4.0 7.0 7.0 9.0 8.0 11.0 11.0 17.0 5.0 12.0 6.0 8.0 9.0 13.0 9.0 9.0 4.0 10.0 7.0 10.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4622464605251473 0.24821307898992373 0.31935043564889154 GO:0008765 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity molecular_function 21.42740635682385 20.751543443284174 18.958654997222165 17.835296041987025 NA NA 21.51914284455114 19.934853199629007 20.4419558614608 21.28466923078943 22.18217498498439 21.7246966864252 22.137546715316052 19.67969922012469 20.013721597466358 17.686403595404414 21.813700558780564 22.097764327205766 21.764929415150302 19.597714200066434 19.111111836899227 18.241139698503584 21.04693782954105 NA 22.43486657996748 21.84037437036871 2.0 1.0 NA NA 8.0 3.0 5.0 7.0 11.0 10.0 11.0 3.0 6.0 1.0 9.0 8.0 9.0 4.0 3.0 2.0 7.0 NA 9.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.6758629135396781 0.12133525035848211 0.17110326830213068 GO:0008774 acetaldehyde dehydrogenase (acetylating) activity molecular_function 26.44271828553369 26.34209550756947 27.48282722545197 26.11186759801869 27.75506137993619 26.56973676132289 24.63650929606211 26.31401132821503 24.34725542025884 26.291057102708802 25.014085571258523 26.40204022516388 25.580847645110047 25.483378373205714 26.268584917985354 26.70205818928964 25.55045902812411 25.48582985388097 27.082154483019856 27.13804840862374 26.892423395787354 26.33561194691245 26.024639782378568 26.269603611779214 26.324843564520375 26.21904216697267 80.0 49.0 90.0 89.0 41.0 66.0 45.0 50.0 31.0 50.0 60.0 53.0 70.0 75.0 37.0 59.0 77.0 75.0 89.0 72.0 56.0 60.0 53.0 58.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.10062277796421881 0.6033317722918665 0.6716842567531217 GO:0008776 acetate kinase activity molecular_function 26.709471969752467 24.679360035160283 24.445038723054253 20.81994993583984 23.669418847781586 22.923303475887426 26.70160539762402 24.91690986239479 27.531365899312977 25.51620055608064 27.56787303592753 25.046743000740207 27.055502345621942 24.04483490496509 27.386642121959962 24.125599536259546 26.13930364142013 25.109718025861863 26.109419979309784 25.357405405550946 25.102785790456448 24.51691291153347 26.99064678356028 23.66537995905818 27.140413746099767 25.460336143974523 17.0 2.0 6.0 3.0 42.0 21.0 45.0 17.0 38.0 20.0 35.0 12.0 35.0 18.0 29.0 17.0 46.0 38.0 25.0 12.0 40.0 20.0 43.0 19.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.0301119345921848 0.00268017172806849 0.006910856026093958 GO:0008777 acetylornithine deacetylase activity molecular_function 25.373506196532286 23.35861001683748 25.591314373367748 18.597931691861472 NA 15.323456823796725 23.518215420838803 21.93751889638045 24.632013439926023 24.210253274269625 25.866649601344214 25.689943234655072 25.99141054149098 23.585976676795894 24.959786826699986 19.772232598396627 24.10511817522722 21.3851945738861 25.177156181441386 23.39947360274096 26.32512701039884 23.039656739856788 26.152474954363562 20.79425402526069 23.78220491641709 23.669612849138232 5.0 3.0 NA 1.0 4.0 7.0 6.0 6.0 6.0 7.0 6.0 8.0 8.0 3.0 5.0 6.0 6.0 8.0 9.0 9.0 7.0 5.0 6.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.014896179694805 0.0008890490306585474 0.002958755174031646 GO:0008794 arsenate reductase (glutaredoxin) activity molecular_function 19.67085414421488 21.05763787961033 18.76265888443553 21.392492859849245 20.82665263154486 18.701980449680992 17.299446352833687 21.68178657538127 20.143941121224533 21.694551081792003 19.128935398546073 21.139359418618646 20.43449553059936 21.41057630511569 19.367438608227815 18.756433624393026 17.31889388669507 21.193534069845093 17.66852862849209 21.07447744081523 19.200581968133065 19.61891612684756 20.221120784735827 21.581007655421075 20.543579434657115 21.046079062124182 2.0 3.0 1.0 3.0 1.0 7.0 5.0 7.0 3.0 7.0 4.0 4.0 3.0 3.0 1.0 6.0 1.0 5.0 2.0 2.0 4.0 4.0 5.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.3867837353954506 0.004669131805023211 0.010994483948432015 GO:0008797 aspartate ammonia-lyase activity molecular_function 26.61952096898408 23.65422437589745 23.708059234682395 NA NA NA 25.609526915504645 22.469081691155168 25.34587735426033 24.244510977696123 26.311379466326798 24.788796752918838 26.610146291121545 17.583782247908974 25.118267340242056 21.074941480118934 24.43190931278019 22.42408289022609 28.852154560645324 25.12382527473672 26.80057953935945 20.660392439612643 26.474669222093105 18.890927071906518 26.37630796781996 24.867632765955786 11.0 NA NA NA 13.0 7.0 19.0 18.0 12.0 13.0 15.0 2.0 20.0 4.0 10.0 7.0 16.0 19.0 16.0 4.0 15.0 3.0 13.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.965296593086631 0.0009341593087812007 0.003100613875954624 GO:0008804 carbamate kinase activity molecular_function 22.564310660876288 21.832754668184137 22.77919625092235 19.24096461787265 NA NA 20.148823952572716 23.35588087426884 22.30662019825442 22.216970994374428 22.608068052919243 23.324682515765012 22.582302482730192 20.48863607294296 22.22498392706854 19.81877455523695 21.92132225468556 20.85155854262275 23.414479436618546 21.794505027427935 20.90613968441512 18.974635856447183 24.016001762786626 20.471912973592698 21.524953418064705 22.087397253573023 3.0 1.0 NA NA 1.0 16.0 4.0 3.0 3.0 3.0 2.0 2.0 5.0 1.0 3.0 4.0 8.0 3.0 1.0 1.0 2.0 1.0 2.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.7315559926921509 0.06128234531845052 0.09584005884389254 GO:0008815 citrate (pro-3S)-lyase activity molecular_function 24.69639006701784 22.025079984223623 21.090685719923663 NA 22.5052937815715 NA 24.852183490885484 20.80812206578253 25.28434975941413 22.95227878675233 24.69914492218916 23.04553847426905 25.57742508018493 21.79950889915363 24.709630670295585 18.993427198932128 25.467092691425748 21.796927369463987 21.941443982700925 22.309484251489497 21.855405012109863 20.38773655725384 24.01952788732769 22.285435825110717 26.08019541034401 22.12439810892805 8.0 NA 10.0 NA 22.0 10.0 21.0 15.0 14.0 20.0 34.0 14.0 20.0 5.0 24.0 15.0 16.0 13.0 12.0 7.0 30.0 18.0 19.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.6713100827942178 0.0068621718926084535 0.015211350838322113 GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity molecular_function 22.760437307513122 22.127873996147386 21.27385112104645 NA NA 17.675616262985624 23.85428811872773 23.28030966763025 23.659150762225696 22.761083445899033 22.56271085147241 14.887191971841128 20.89019232416834 19.635351884042443 22.483069524101683 22.66063241223194 23.60228967910287 22.97917885079433 20.22300148436682 18.627237787251307 21.102908071005352 21.616778216698734 22.834740181254748 NA 23.18195265633261 23.09522561867012 3.0 NA NA 1.0 10.0 8.0 9.0 9.0 8.0 1.0 7.0 1.0 5.0 5.0 12.0 5.0 5.0 1.0 3.0 3.0 6.0 NA 10.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.6325633113657361 0.23126604315548327 0.30285416774191304 GO:0008838 diaminopropionate ammonia-lyase activity molecular_function 23.336481258080106 21.927431245386014 23.630714109832144 NA NA NA 21.22754041137729 20.070677343375454 23.583372441147226 22.539507324479327 23.1526999951362 23.96006255468804 23.07636599215364 20.031496965741216 22.23578090998975 19.40564149697333 23.2291694019723 16.755988999671132 24.444493247510138 22.604137742787433 23.79335986051457 21.595893956556548 23.470309964934767 16.541296141112788 22.646886729554833 22.209906134701995 9.0 NA NA NA 6.0 5.0 9.0 10.0 9.0 10.0 8.0 4.0 7.0 3.0 8.0 1.0 10.0 10.0 10.0 6.0 12.0 1.0 8.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.4090500126940917 0.00602721213253396 0.01362674047355504 GO:0008861 formate C-acetyltransferase activity molecular_function 28.16309778459177 27.046961011821708 28.129315590770922 25.092393922377273 28.363996153806266 27.539609009542406 27.75112970311081 26.909921211398128 27.34086039007489 27.11350425704135 27.58922140212043 27.12329544975003 27.892382569567772 25.23533073175674 28.45795512522639 27.243729244739534 27.14938862227271 27.28719493090146 29.4651114384317 27.47792567922585 28.45546356477628 27.28151055888548 28.08756605298656 27.005125715453314 27.63703793184105 27.32884294410553 85.0 29.0 93.0 84.0 89.0 77.0 94.0 74.0 95.0 80.0 90.0 35.0 121.0 66.0 71.0 72.0 126.0 118.0 103.0 64.0 102.0 67.0 91.0 80.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.1161367727700622 0.00021985068263840352 0.0009941074345388681 GO:0008865 fructokinase activity molecular_function 19.753335050838547 20.753061320470632 20.21652301490129 21.47364304142184 20.709685047655515 NA 18.65855218950387 21.75225516891745 17.601868587063574 19.46201032369804 19.551477931963426 21.622601140834913 18.50881585353373 20.182865066966432 16.619422323586928 18.235497062171373 19.745726980889486 19.820515292224613 18.14780096498388 22.254321599781857 20.76542647943199 19.874513924183386 20.295444016479394 16.579318678080522 20.59010354736724 19.087490026030753 5.0 4.0 6.0 NA 2.0 5.0 2.0 3.0 3.0 3.0 2.0 2.0 1.0 1.0 1.0 4.0 2.0 8.0 4.0 3.0 4.0 1.0 7.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9997262696320846 0.3247557654026184 0.4012639356708831 GO:0008878 glucose-1-phosphate adenylyltransferase activity molecular_function 23.352520112464155 22.5445681213738 24.25180508656333 22.244299098330927 24.207929767791324 22.465581537816387 22.820760008617725 22.998998720737482 22.64543495325809 21.8437968296493 22.88346936002101 22.502782010414094 22.461821291310034 21.590012286049447 23.822975995317172 23.090797018388127 22.64160379652525 21.997398305504294 22.56436493662528 22.434418032353392 23.358199735432034 23.481011343566518 22.146000491396254 22.503500948857496 24.157157090146235 22.243023067280113 11.0 5.0 16.0 3.0 11.0 7.0 13.0 8.0 16.0 7.0 12.0 3.0 23.0 7.0 10.0 7.0 19.0 9.0 12.0 8.0 10.0 7.0 22.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.8079519910903556 0.017926339076638688 0.03379466943753034 GO:0008879 glucose-1-phosphate thymidylyltransferase activity molecular_function 21.92696925688943 22.85959828024805 22.40960322188168 22.66318199148706 23.41333612372455 22.0612030450556 21.050134559226013 22.388800868671748 20.783441183939946 22.380940061696357 21.955955951255213 23.53271519335704 22.670012767731176 23.83848507946891 19.43129097246662 22.65930521005616 20.9790408667988 21.023123244831297 21.565359364115096 23.49436074476233 22.139315673677007 22.75831410744499 21.160630696213865 22.590281931651287 21.75757285898837 22.97416635984489 2.0 3.0 4.0 2.0 3.0 3.0 2.0 3.0 4.0 4.0 3.0 3.0 1.0 3.0 3.0 2.0 4.0 3.0 3.0 3.0 1.0 2.0 3.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9326290233586221 0.009374768459434895 0.01937038251220985 GO:0008888 glycerol dehydrogenase [NAD+] activity molecular_function 21.528974789163843 21.873086603620468 19.80237395383873 NA 20.103539704394464 20.193112749875848 NA 19.207967742634764 NA 22.133433302487564 NA 21.381377535469703 20.70087484452471 21.757164856975642 18.331166823777927 22.984891672359645 NA 20.451139400390094 23.706574048556448 22.07274654901332 20.412991344807352 19.694257254542602 20.217977100760642 17.359071127064354 21.867947211978606 23.78039836569857 1.0 NA 3.0 3.0 NA 3.0 NA 10.0 NA 4.0 5.0 5.0 3.0 6.0 NA 2.0 9.0 8.0 2.0 4.0 1.0 2.0 3.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.34411181445662464 0.5632600841286355 0.6360770084449954 GO:0008901 ferredoxin hydrogenase activity molecular_function 23.072689267335853 22.442794953029352 19.883732822434823 NA NA NA 20.167156891300333 21.07309076826013 21.8795248327187 23.47922068112573 21.232977688247548 22.63881049558249 22.918048271919517 21.246419632355614 22.09283839852064 20.307487966969187 21.20752387875584 21.868954910347 25.57492378582209 22.08426848802526 22.058739691594948 19.40661338428738 23.70762758546145 19.984595644296025 22.443642216873805 24.441606256499142 3.0 NA NA NA 5.0 5.0 8.0 14.0 8.0 11.0 14.0 8.0 9.0 2.0 8.0 6.0 28.0 12.0 9.0 2.0 14.0 6.0 14.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.629894314306501 0.5262368666518372 0.6008633207515945 GO:0008912 lactaldehyde reductase activity molecular_function 21.814107203143077 21.082175205144146 NA NA NA NA 20.42360697410732 21.505914971000248 20.975607937421483 22.540875887919906 21.202842964823233 20.672722610315144 23.24872581537283 NA 22.502098338221067 18.745835022395013 21.285022976373238 21.189379040885765 20.49736681577028 18.03912848263873 21.806388878185807 18.12888604223489 22.61008237817921 NA 19.899388686625677 21.78836917878064 NA NA NA NA 4.0 3.0 2.0 5.0 4.0 3.0 4.0 NA 5.0 2.0 6.0 3.0 3.0 2.0 4.0 1.0 2.0 NA 2.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.7319319979989309 0.24805753990202628 0.31935043564889154 GO:0008940 nitrate reductase activity molecular_function 22.230221213688026 22.14314743790698 21.15769621161284 NA NA NA 21.685857732362685 21.452691880313434 21.160992626093442 23.42998533215525 21.595328775491616 23.26507024249836 23.304349024410552 20.337320977674587 21.87472639480513 18.97128037405427 21.731839995782607 22.221510064722768 21.39952566972045 20.87763775791877 22.815217998716324 19.613522195969104 23.56966435366005 22.116912494239788 21.31558193877046 22.94234501156301 9.0 NA NA NA 10.0 12.0 8.0 23.0 9.0 17.0 14.0 7.0 9.0 4.0 11.0 14.0 14.0 7.0 9.0 5.0 18.0 9.0 10.0 17.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.08707377578104669 0.6220654737597032 0.6911306926646184 GO:0008948 oxaloacetate decarboxylase activity molecular_function 23.239471460341694 23.32962639229865 21.48581239050037 NA 22.62455783255401 NA 23.75377108890841 23.153584684187397 23.02515864610588 24.121951323156594 22.390773855595498 22.278223065524454 22.90605119314207 20.639341302341172 22.938990336941718 22.40336653080604 23.924406036298407 23.53949322799873 22.88042864541649 21.438102700012287 24.21567507115732 23.963714284462103 23.893436720106592 21.43126402345495 22.664340861737948 24.901569550012045 7.0 NA 14.0 NA 6.0 5.0 10.0 8.0 5.0 3.0 7.0 3.0 11.0 7.0 5.0 7.0 9.0 4.0 14.0 9.0 12.0 3.0 6.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.09015493195695612 0.6443923436450455 0.7073013587238495 GO:0008959 phosphate acetyltransferase activity molecular_function 24.783124157180506 25.309305360457696 25.774142536264833 24.506274919739862 25.387129314322337 25.555859981278022 23.304697982840104 25.211470597794037 22.13645509649633 25.14282837838018 24.33331084569561 25.83779875047463 24.583799750933967 25.030162744316048 25.56153187408507 25.18459362001071 23.67793756660357 24.50296424487868 25.59202242417376 25.053448424132252 25.416424247555 25.76962222738116 23.247241069099307 25.85601378946437 23.90185191102901 25.2881341735674 19.0 13.0 21.0 13.0 16.0 18.0 11.0 14.0 18.0 24.0 11.0 13.0 29.0 12.0 11.0 11.0 32.0 16.0 15.0 16.0 10.0 13.0 13.0 16.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.52618120327719 0.13332693177434943 0.18549833985996442 GO:0008965 phosphoenolpyruvate-protein phosphotransferase activity molecular_function 25.18716594053853 26.786259572248955 26.092193246598 26.10865492327304 25.817366803485946 26.982230447268872 24.111668904330173 26.682779481036743 23.476964175998692 26.15654039181284 24.464926458903623 26.669298020002927 25.332538553344087 26.760212079293193 26.357242407360808 27.202605326502198 24.351069818758532 26.96723711069377 25.404407752988682 26.83155958700921 25.26561313820735 26.51659614725656 23.423252764809078 27.401112278032198 24.79901972518721 26.61322235783212 26.0 29.0 38.0 42.0 25.0 48.0 18.0 46.0 29.0 33.0 29.0 20.0 35.0 38.0 20.0 49.0 42.0 40.0 32.0 31.0 27.0 40.0 29.0 43.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.5990936317104243 5.312128159411724e-05 0.0005099643033035255 GO:0008966 phosphoglucosamine mutase activity molecular_function 23.8676709347336 23.765990192536343 22.48546849404002 23.105485051784893 22.441202730270387 23.759018080271353 24.1176025837639 24.31644357586124 24.214401906829988 23.74193177768353 24.675354375555905 24.03633532130393 24.220898429407292 22.798870540223998 23.292256744029235 24.223380945487264 23.952488822862968 23.789145805782113 23.592532952531233 24.374322367998435 22.89527967075387 23.3214721296964 23.60130644087987 23.19858815893117 24.760330155641192 23.58670599721213 12.0 10.0 9.0 14.0 25.0 19.0 21.0 21.0 29.0 24.0 32.0 7.0 20.0 20.0 25.0 16.0 24.0 27.0 15.0 14.0 28.0 15.0 31.0 25.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.10168074219725654 0.9539596927720386 0.9577970205788449 GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity molecular_function 25.94084468597536 26.31957655122036 26.545572228420127 26.073730715215394 26.33487109001171 25.909762880851137 25.22540707749368 26.974410882272178 25.680634082692556 26.89509409083169 26.101881858639693 26.704618593549355 25.382078194453893 25.394771546336926 26.24751954458256 26.051000751990827 24.486830699048696 26.675140581081124 26.58856295380903 26.111056177505198 26.56259815711493 25.77214371284606 24.74609972279113 25.961434113453368 25.582647575534875 26.413417674525213 37.0 26.0 52.0 43.0 22.0 44.0 22.0 41.0 30.0 37.0 35.0 20.0 36.0 50.0 21.0 38.0 46.0 35.0 42.0 39.0 20.0 44.0 36.0 43.0 2.0 2.0 2.0 2.0 1.0 2.0 NA 2.0 1.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.37873186524500113 0.13332693177434943 0.18549833985996442 GO:0009024 tagatose-6-phosphate kinase activity molecular_function 23.411353701163545 24.853624103628178 24.445074912926717 24.810424465139732 24.876346104172818 24.249228351478084 23.229945510219288 25.54997765642075 17.829756253830322 24.99295740462455 19.691261902405127 25.03562572544493 22.648951316398268 24.971284339308372 24.91816950306654 25.36193382779769 21.988050830348765 24.73574868814073 24.23687553955513 24.346019325708948 21.889494052794266 24.53528647581933 19.94916118927913 24.32845451843637 21.075907601073208 24.679549349372145 22.0 26.0 27.0 25.0 11.0 36.0 2.0 33.0 5.0 31.0 11.0 20.0 24.0 35.0 11.0 39.0 22.0 26.0 10.0 31.0 4.0 24.0 10.0 30.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.442270402464633 0.0014961642897455532 0.004424675435076897 GO:0009025 tagatose-bisphosphate aldolase activity molecular_function 23.337062291839377 24.105526990203696 24.36560110293243 24.33454411427051 24.644820452899232 23.921369687366845 23.39040544297857 25.05545426513236 17.829756253830322 23.73918435562253 19.691261902405127 24.078901053434357 22.55369599896606 24.43838587915173 24.889721467646734 24.86856642492755 22.21391957670815 23.50120544342416 24.212164912973318 23.23416912900764 21.655572891048312 24.09248544155727 19.153551462158244 22.054134992423858 20.783408436209093 23.89685160273641 18.0 16.0 22.0 15.0 11.0 22.0 2.0 19.0 5.0 17.0 10.0 11.0 20.0 21.0 11.0 19.0 21.0 16.0 9.0 18.0 3.0 11.0 8.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7684646983643191 0.0832645166635504 0.12534875367444018 GO:0009040 ureidoglycolate dehydrogenase activity molecular_function 26.94499451928872 27.688583542784357 26.4579243667998 18.36452559301795 NA NA 26.243074484914125 28.103931642608032 26.337829819516678 28.313684459924925 25.841547353730412 27.42308022502724 27.005351545289663 26.42175006635157 26.876615960173417 26.973446497882023 27.833828119376374 28.560710624111948 27.43844249478407 26.79380626171308 27.64488207488489 27.55872417854309 26.64994327604288 25.437512856201835 26.718225709318308 29.16039301364717 12.0 3.0 NA NA 11.0 14.0 12.0 14.0 8.0 11.0 11.0 11.0 14.0 13.0 9.0 14.0 10.0 13.0 17.0 17.0 13.0 12.0 12.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7435890234956375 0.2785986718379625 0.3526279335231006 GO:0009056 catabolic process biological_process 32.79086100080459 32.70004420406532 32.5665122098972 32.177412648062784 32.5508820009463 32.78670519106322 32.40548118697896 32.92878824962782 32.706845180920766 32.433454186594155 32.98399507964782 32.56288612609114 32.78163130772798 32.08828277161263 33.230983052923264 32.93443169007721 32.17095851759339 33.00568502612667 33.347791383611366 33.362086882458726 32.03676847107376 32.66937616932505 33.186230799456396 32.50311698004869 32.8811987810484 32.429692599901465 2150.0 1912.0 2639.0 2698.0 2769.0 3130.0 3416.0 2648.0 3548.0 2807.0 3452.0 2109.0 3779.0 2588.0 2462.0 2455.0 4746.0 3952.0 2978.0 2301.0 3213.0 2087.0 3148.0 2638.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 0.09081679673926857 0.6861059569955559 0.7413508522341591 GO:0009057 macromolecule catabolic process biological_process 25.584639420373286 26.153126530848645 25.339880644937463 25.904689584044572 25.20217643388369 25.96896623575861 25.25331816538395 26.186889201304087 25.794840254066486 25.319568221391428 25.66530569182921 26.241500441331826 26.05230484288434 26.730845290628697 25.44111700016443 26.169622524387993 24.774550272435693 25.6661877578964 26.093315643401766 26.018710133201882 25.42193341572155 25.70853441869661 25.84598608089947 27.017876176988867 25.59404522417569 26.072518435792546 72.0 91.0 53.0 111.0 74.0 106.0 96.0 85.0 89.0 117.0 112.0 102.0 89.0 124.0 61.0 116.0 147.0 111.0 77.0 80.0 102.0 125.0 89.0 112.0 4.0 4.0 4.0 3.0 4.0 4.0 3.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 3.0 4.0 4.0 -0.5684871104753597 0.005583616806378765 0.012692811975156102 GO:0009058 biosynthetic process biological_process 35.56922205935716 36.16935598905237 35.54848039990903 35.52863517652071 35.169127971092024 36.06288545382709 35.20361084047347 36.31039315616254 35.258668140885874 36.09840946502317 35.74361668225314 36.16214717962965 35.73700421043297 35.80251072000898 35.91660307081978 36.509390299786745 35.126962729268705 36.52723139841554 36.18140108188221 36.33887963708165 35.552300888114914 35.99849268014733 35.49791590312665 36.330734983266936 35.488005693507745 36.05823675690066 25346.0 24956.0 23394.0 30478.0 27798.0 39510.0 31698.0 37459.0 32667.0 38267.0 35356.0 29168.0 35701.0 38002.0 27840.0 39065.0 44106.0 42239.0 31845.0 31102.0 33915.0 36118.0 33651.0 38354.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 4.0 -0.6001339296952111 0.0006583371695572323 0.0022696264851033866 GO:0009059 macromolecule biosynthetic process biological_process 31.28374037055109 31.019976533657683 30.635659001424308 30.39674227683499 30.21955899224195 30.862372898784795 30.81427094005436 31.14350550967585 31.37505115514885 30.88250272420835 31.420448088678732 31.280066719668977 31.45986223303907 30.95461803377234 31.589984390728283 31.229348829560852 30.88419288831637 30.84065138789775 31.989244010872607 31.382931161391358 31.09885741606447 30.727389939157117 31.78887127461645 31.20187232376948 31.19839207076613 31.0574813409807 1081.0 877.0 788.0 1145.0 1123.0 1325.0 1426.0 1233.0 1465.0 1391.0 1398.0 1118.0 1706.0 1284.0 1144.0 1214.0 1944.0 1709.0 1202.0 917.0 1444.0 1238.0 1326.0 1306.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 0.263763836893407 0.2040238704744366 0.2705863871967023 GO:0009063 cellular amino acid catabolic process biological_process 29.26501273223423 27.05326358598209 28.51240941601684 26.71968074183655 28.412408497985115 26.826570570025293 29.019290515565434 27.30620288671978 29.53932952038982 26.472977862898226 29.68968241009048 27.653080258285517 29.364735438551183 26.270280585863446 29.55227924917904 25.74425374658947 28.796454556999336 25.68951966274158 29.443669919137754 28.77892892326214 27.81327662511193 27.64106163659245 30.032005176026484 22.89402192528243 29.57987721705741 26.61158496037261 73.0 55.0 150.0 107.0 164.0 100.0 237.0 74.0 259.0 85.0 231.0 66.0 234.0 53.0 147.0 41.0 266.0 210.0 169.0 72.0 213.0 21.0 207.0 79.0 3.0 2.0 3.0 3.0 4.0 2.0 4.0 2.0 4.0 2.0 5.0 2.0 4.0 2.0 4.0 2.0 5.0 3.0 4.0 2.0 5.0 1.0 3.0 2.0 2.2117491462521386 6.784570247173055e-05 0.0005498145239267514 GO:0009064 glutamine family amino acid metabolic process biological_process 29.067312585869193 28.35019774410615 29.248063521952357 27.487620511711125 29.34452909542593 28.646130966038164 28.549752061527066 28.45246608561273 28.84636275225245 28.080164234459826 29.239525951015953 28.766421208739228 29.161570210583182 28.05564985597733 29.282364117283894 28.33726093509565 28.37972390752235 28.367076143863677 29.34041976789984 28.495670545561858 28.695780206950012 28.662068347387727 29.272689181255174 28.50265691722424 29.049640717422285 27.852266603471108 138.0 168.0 310.0 317.0 200.0 346.0 275.0 256.0 298.0 281.0 298.0 237.0 291.0 299.0 196.0 329.0 361.0 299.0 290.0 235.0 318.0 289.0 250.0 249.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 5.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 0.717114841763042 0.00034415785384659113 0.0013990521224773477 GO:0009065 glutamine family amino acid catabolic process biological_process 26.24801173746915 25.49511162860752 27.345989772364256 24.55105852459021 27.298886370651026 26.338541075515 24.85331477947361 25.768969398666677 25.442240225599623 25.182111302212192 25.757819925084114 26.234954400549523 25.287502549178967 24.94532658104153 26.445789130932976 25.2614337993105 24.978307007204165 25.52290048889289 27.31123563195261 25.044406239998807 26.614618446564346 26.60211273679434 23.89651342190709 22.1902132027093 25.1677819479028 24.38120612463305 12.0 7.0 41.0 39.0 12.0 16.0 18.0 8.0 22.0 12.0 11.0 10.0 12.0 12.0 5.0 20.0 43.0 8.0 27.0 13.0 26.0 11.0 11.0 9.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 1.0 3.0 2.0 3.0 4.0 1.0 2.0 1.0 3.0 3.0 2.0 2.0 2.0 3.0 3.0 1.0 2.0 0.7529001088616276 0.2040238704744366 0.2705863871967023 GO:0009066 aspartate family amino acid metabolic process biological_process 28.32660448276641 27.700704956286717 26.21815901875106 26.73548360152667 25.79819647073239 27.080526338488887 28.208131747585462 27.51786065820401 27.95997746828805 27.133058955194397 28.692204489667137 27.803869113366428 28.67765731829989 27.74107260363265 28.49006822954354 28.164516604373922 27.797835430992798 27.885470179836183 29.74811838986857 28.031818970649272 28.1252019418618 26.954697063874512 28.175599871509608 28.59729521271381 28.4269066093617 27.622623811591392 153.0 172.0 160.0 224.0 205.0 312.0 151.0 268.0 218.0 320.0 287.0 243.0 195.0 272.0 156.0 306.0 323.0 301.0 274.0 212.0 280.0 308.0 229.0 305.0 7.0 6.0 6.0 6.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 5.0 7.0 7.0 7.0 7.0 7.0 6.0 7.0 5.0 7.0 7.0 0.6258995264796923 0.04964722965745621 0.07872902492059129 GO:0009067 aspartate family amino acid biosynthetic process biological_process 25.26375183428764 26.482197612228962 24.88043411509589 25.692909296264595 24.64119877845326 25.933022961196603 25.189321112056433 26.420984879138278 23.909253620663232 25.93578004803927 25.20756313816793 26.47649166875154 25.854911029315527 26.73117808642861 26.58063291843689 27.000069480568147 24.203524405675005 26.7007894881274 25.155061808844003 26.150389213934712 25.179682142967625 25.84100924532976 25.32636741595728 27.480004382457 25.093609896962327 26.301437700107478 66.0 80.0 72.0 99.0 64.0 141.0 44.0 119.0 66.0 143.0 109.0 117.0 66.0 128.0 57.0 140.0 100.0 116.0 108.0 99.0 102.0 145.0 81.0 134.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -1.218445777941323 0.00034415785384659113 0.0013990521224773477 GO:0009069 serine family amino acid metabolic process biological_process 27.598263151064806 27.694559138159523 27.00055584513669 27.379428121624866 27.47221897801752 27.546643842506825 27.94692144349079 27.416996480387784 27.925859210422 27.307174210991988 27.90071085343309 27.967670072700987 27.475220170418826 27.93415166836996 27.265326130841185 27.904748934474444 27.13350432033977 27.569210597895328 28.172788940800384 28.203674763096647 27.186560639038113 27.490376762413906 27.648652646918364 27.799773963349303 27.52136988904598 27.50127945768452 116.0 137.0 188.0 190.0 165.0 186.0 173.0 187.0 197.0 191.0 188.0 142.0 188.0 169.0 123.0 190.0 289.0 214.0 225.0 151.0 192.0 173.0 175.0 186.0 6.0 5.0 6.0 7.0 7.0 6.0 7.0 6.0 7.0 7.0 7.0 7.0 6.0 7.0 7.0 7.0 7.0 6.0 6.0 7.0 7.0 7.0 6.0 7.0 -0.09629598709471665 0.3556110610952391 0.43337630976650365 GO:0009070 serine family amino acid biosynthetic process biological_process 26.11318080750389 26.43870138491111 25.660419483011953 26.098460718222732 25.57897863958904 26.162564142283024 26.486109011336 26.227962355164767 26.52213577959225 26.038927750958685 26.510536395689932 26.702173249906963 26.09732555489614 26.610809233417395 25.878241309894662 26.72216057421941 25.70527431446679 26.4276214673282 26.461746537824826 26.904793233168203 25.59753442756773 26.27886828036437 26.17009649665655 26.58710183510653 26.160722748800865 26.18864279401773 44.0 53.0 49.0 50.0 62.0 68.0 68.0 73.0 76.0 72.0 68.0 47.0 74.0 67.0 47.0 75.0 91.0 80.0 66.0 59.0 68.0 66.0 70.0 72.0 4.0 3.0 2.0 4.0 4.0 3.0 3.0 2.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 3.0 4.0 4.0 4.0 3.0 -0.32552057740721807 0.02824036873330045 0.04901805310036017 GO:0009072 aromatic amino acid family metabolic process biological_process 29.225075099092077 26.799702422409624 27.79917340241513 26.66015960513285 27.209359685933727 24.62700127363798 29.14017554026937 27.068068595775234 29.384841487132288 25.92041723849184 29.711795016959194 27.40572453380358 29.401001381434327 25.74555319310985 29.50381827780617 26.476375110822445 29.020053852002665 24.715196621807962 28.567517367291288 28.496100903949266 28.31747624954308 26.75988464062696 30.204302379707517 26.45973516667253 29.87632262806601 26.910644550048946 66.0 62.0 82.0 65.0 139.0 107.0 217.0 104.0 220.0 116.0 227.0 86.0 221.0 82.0 143.0 64.0 178.0 212.0 120.0 80.0 171.0 51.0 197.0 96.0 5.0 5.0 3.0 4.0 4.0 5.0 5.0 4.0 4.0 6.0 6.0 6.0 6.0 4.0 5.0 6.0 5.0 5.0 4.0 4.0 4.0 5.0 4.0 5.0 2.4253726766824535 8.637667594722788e-05 0.0006159890947550879 GO:0009078 pyruvate family amino acid metabolic process biological_process 21.57801657455614 21.999033778694272 22.819012029215934 21.363026045503954 20.57856069100217 20.62667408657724 21.955548692862955 22.29321523313521 21.67662208401689 22.70536665730952 22.74862000779889 22.899676573026962 21.77097037805543 22.1346018229089 19.538105822408834 20.46329643919817 21.769653455599776 18.70108290610442 20.10834268670508 22.475547955595164 19.899298398866197 20.44312480447125 19.73156186889231 22.17255787209275 21.628265619116693 22.879606195031904 15.0 7.0 4.0 4.0 8.0 10.0 16.0 15.0 23.0 19.0 12.0 15.0 4.0 12.0 16.0 4.0 8.0 19.0 4.0 8.0 4.0 11.0 8.0 19.0 3.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 -0.42101720413813126 0.24821307898992373 0.31935043564889154 GO:0009081 branched-chain amino acid metabolic process biological_process 26.126968564177083 28.854957589364123 27.38874182033795 27.4666863830248 26.4652520920848 28.38116686809904 24.25296133515901 28.297571379575878 24.221384534345226 28.65257772951332 25.945769730295034 29.319453696342322 26.443544048195623 28.330843995422374 26.723925085806602 29.50773640136384 25.489565110273148 29.795788167686982 26.65782017786412 28.61473018532577 25.906034946937776 28.117884497533804 25.451030063021 29.40669388690509 25.357599246053468 28.6537058970322 181.0 247.0 149.0 294.0 74.0 357.0 74.0 417.0 163.0 392.0 162.0 280.0 208.0 507.0 120.0 554.0 165.0 317.0 173.0 382.0 173.0 454.0 139.0 403.0 4.0 4.0 5.0 5.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 5.0 4.0 5.0 4.0 4.0 4.0 -2.727989025187039 3.225641456243767e-05 0.0005099643033035255 GO:0009082 branched-chain amino acid biosynthetic process biological_process 25.099548778578658 27.81669861463234 26.38584201993579 26.46871632747744 25.355311820362164 27.364533843897142 23.184032092762973 27.236745088888608 23.22284533453492 27.529636747133626 24.93900007612989 28.292987521407102 25.442059393166215 27.29922816476787 25.717259222532693 28.49534106237452 24.413749030458984 28.774821629820448 25.64739764166903 27.57262863372177 24.888531467656158 27.092953865804787 24.376310552327105 28.39881758456501 24.31200922685264 27.508338494767465 90.0 124.0 72.0 145.0 35.0 173.0 37.0 203.0 80.0 192.0 80.0 136.0 103.0 250.0 58.0 272.0 81.0 155.0 85.0 187.0 85.0 224.0 68.0 196.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -2.7171498360536823 3.225641456243767e-05 0.0005099643033035255 GO:0009084 glutamine family amino acid biosynthetic process biological_process 24.983986307791266 25.85458160424028 23.735713609935473 24.205685380228573 25.678258092349147 26.146267072843084 24.927493077431564 25.798718856657036 23.647000577722654 25.826328738995446 24.66716872912498 25.74054824456913 25.49280200925667 25.37905064059932 25.14193335161091 26.272715686008787 24.83690845538567 26.44099531144116 25.28929813818189 24.741568832198766 25.175266731960694 25.278742849984546 24.77638737819991 26.94171697845081 25.14180459929192 25.48827860013228 19.0 37.0 57.0 65.0 26.0 79.0 28.0 58.0 28.0 63.0 43.0 61.0 38.0 77.0 26.0 86.0 53.0 48.0 48.0 52.0 49.0 87.0 30.0 57.0 4.0 3.0 4.0 4.0 3.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 2.0 3.0 3.0 4.0 3.0 3.0 4.0 4.0 4.0 4.0 3.0 4.0 -0.8705952964490145 0.007911788680711459 0.016907384030013527 GO:0009088 threonine biosynthetic process biological_process 23.27686757719531 24.874234887286313 23.26451122277198 24.220544826370894 23.146999104279285 23.90634073091445 22.499248447301213 24.90852355543843 20.5628465534258 24.40477447879674 21.708730036103454 24.84899831506105 23.62356248644293 25.31338769213541 25.22355658330789 25.29894352237231 22.150750340999217 24.837093951275865 23.119658789423838 24.689205266329388 23.199442487405747 24.180069870585257 23.37300365721867 25.91216481833089 22.34325153488121 24.722999253481326 22.0 28.0 27.0 27.0 17.0 43.0 8.0 43.0 16.0 44.0 36.0 39.0 20.0 42.0 18.0 43.0 30.0 43.0 37.0 32.0 35.0 47.0 26.0 43.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.597367310091002 0.0002755038114342687 0.0011655212090507369 GO:0009089 lysine biosynthetic process via diaminopimelate biological_process 24.416762161339086 25.195179097096208 23.992083478086556 24.71690185998027 23.461558908141146 24.46561439509905 24.657422056489853 25.38785333482377 23.07208816708239 24.78911346843997 24.698113069920602 25.315303603171724 25.022314154910266 25.44316575706059 25.58641030104943 25.453511482270983 23.34929266238635 25.3988663163041 24.326028090422433 25.19365374480762 24.249566898198772 24.206099928768463 24.367713988003977 25.83420661529129 24.27138484594737 25.33188073002495 31.0 37.0 25.0 39.0 27.0 60.0 14.0 49.0 25.0 62.0 39.0 47.0 26.0 55.0 23.0 54.0 45.0 50.0 46.0 40.0 34.0 57.0 30.0 51.0 NA NA NA NA NA NA NA NA NA 1.0 NA NA NA 1.0 NA 1.0 NA NA NA NA NA NA NA NA -0.7784169357571216 0.004669131805023211 0.010994483948432015 GO:0009097 isoleucine biosynthetic process biological_process 24.244246920333172 26.88765245588157 25.46227059267324 25.572331126298103 24.488363287169534 26.51528368669641 22.289586078405048 26.349742143701487 22.17074778934793 26.57203550512419 23.96846628022431 27.35562347786636 24.565641527156515 26.489921593484954 24.86236108689507 27.5406128808808 23.55971758823636 27.735024627595234 25.073902509460396 26.635111626116014 23.93372139905412 26.204845397659263 23.578561717185675 27.52102462334698 23.37432094569746 26.576493990183245 48.0 67.0 40.0 79.0 18.0 91.0 19.0 102.0 40.0 97.0 41.0 75.0 55.0 127.0 30.0 126.0 43.0 85.0 45.0 96.0 46.0 111.0 35.0 97.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.6434055355484 3.225641456243767e-05 0.0005099643033035255 GO:0009098 leucine biosynthetic process biological_process 20.702455402088454 23.65331812526396 20.55985971812525 22.062140628968272 19.59698841966476 21.961904898885003 18.75640065451706 22.611092693961698 20.807615410091497 23.667325284119205 19.95333805134868 23.874388139014226 21.255928300023662 22.54446320767187 20.182545920745607 24.610105214323177 19.7274383381369 25.154632992453624 22.341930130733253 22.924196219872407 21.09339449215064 22.631948379914466 20.579225787715394 24.537145677425684 20.14731296148288 22.71186976928585 7.0 8.0 4.0 8.0 3.0 17.0 4.0 29.0 5.0 26.0 8.0 13.0 7.0 29.0 5.0 43.0 8.0 14.0 7.0 19.0 6.0 35.0 6.0 26.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.950862723175508 5.312128159411724e-05 0.0005099643033035255 GO:0009099 valine biosynthetic process biological_process 23.748500701477102 26.558613580728363 25.250318246939038 25.192252206835608 24.14848416664249 26.109397922775692 21.917225661553573 25.97285284917184 21.51344721616441 26.26430058324349 23.73855115970517 27.075453142454904 24.032748694739876 25.949271159254874 24.484571260986037 27.227779409337288 23.107881462200165 27.56367104833301 23.50730788175081 26.38161804541455 23.54776239728629 25.816301681664125 22.77126419986009 27.02598732156672 23.04248174662672 26.323348119120894 35.0 48.0 28.0 57.0 14.0 63.0 13.0 71.0 34.0 68.0 29.0 48.0 41.0 92.0 22.0 101.0 30.0 56.0 32.0 71.0 31.0 77.0 26.0 73.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.8101128792512604 4.146041132679973e-05 0.0005099643033035255 GO:0009103 lipopolysaccharide biosynthetic process biological_process 22.19288473845172 20.2508153018588 18.49533426921829 18.79730104465916 NA 18.630741788819343 20.977802025960322 20.05021285590961 20.792564981749443 20.560673534074034 22.218665039010162 20.791407003930733 22.90809503487505 20.451663978596507 21.323506275629086 18.41148212746377 22.060894769047433 19.852511930434872 24.08092975425356 21.564228926206784 21.866490533660738 19.42552143456873 21.60672012841581 20.283171340559488 21.921719773977408 20.82156562771914 1.0 2.0 NA 3.0 5.0 3.0 7.0 3.0 10.0 3.0 12.0 3.0 5.0 2.0 12.0 3.0 15.0 9.0 9.0 2.0 8.0 2.0 9.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.94206943659292 0.0016962207449685985 0.0049575725754585735 GO:0009108 coenzyme biosynthetic process biological_process 29.232082910704218 29.74383088148133 29.21135506890717 29.077374410492467 28.94190197410965 29.78367578927257 28.781728828619237 29.966419825463664 28.690119907693767 29.599247681049523 29.450428338507546 29.576146263089004 29.143430738575805 29.176396109885868 29.919910775875373 30.116099877362355 28.578519554692143 30.27370138102955 30.021019279391442 29.980171469531523 29.34440268946526 29.617222174676947 28.739835207541642 29.773212372843194 29.09240291250813 29.513853314075842 199.0 196.0 213.0 237.0 264.0 327.0 299.0 264.0 282.0 288.0 276.0 237.0 335.0 307.0 229.0 267.0 425.0 348.0 265.0 236.0 278.0 296.0 290.0 270.0 9.0 9.0 7.0 10.0 9.0 10.0 11.0 11.0 11.0 12.0 11.0 11.0 12.0 10.0 12.0 10.0 11.0 10.0 8.0 7.0 10.0 12.0 13.0 13.0 -0.5117479707771118 0.007911788680711459 0.016907384030013527 GO:0009112 nucleobase metabolic process biological_process 28.165482679199272 28.396262711595373 28.11687526172843 27.64816757808009 27.03062528965466 28.249079958963836 27.67508954661687 28.18686916174095 27.84248726849733 28.68832377346229 28.731559827772593 29.127944539313912 28.790330925301472 28.407819806669067 27.827627606126825 28.187941061934342 27.773852993664843 27.968228390206644 28.25359676503109 28.40499798676534 28.53735929853653 28.29511111788725 28.539970106286503 28.81009349353489 27.908940656003328 28.185859111072784 154.0 148.0 90.0 155.0 178.0 217.0 240.0 249.0 189.0 235.0 218.0 176.0 248.0 190.0 193.0 220.0 249.0 257.0 185.0 175.0 219.0 193.0 206.0 206.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 3.0 3.0 3.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 -0.23078003239610112 0.2253456937016668 0.2954111614912607 GO:0009113 purine nucleobase biosynthetic process biological_process 23.74679250825063 25.236753181518345 24.63384511765479 25.337920507546702 24.094702355994645 26.040872780741363 23.471011364158624 24.91726206116069 22.56610137962672 24.849276969703283 24.10745097819021 24.754434426210945 24.51243096810844 25.291380678018648 23.56248424994412 25.63197998943989 23.140112676982888 24.768614630819982 22.209091020050835 25.481218693444728 23.318556446588172 25.32061292592236 23.52977237189672 25.604640241331676 23.93821870460764 23.44105661751265 12.0 27.0 12.0 22.0 12.0 26.0 11.0 20.0 12.0 20.0 17.0 21.0 17.0 32.0 9.0 26.0 14.0 27.0 12.0 25.0 5.0 17.0 10.0 18.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.489960673267717 0.00021985068263840352 0.0009941074345388681 GO:0009116 nucleoside metabolic process biological_process 28.864538528153574 29.902413254245246 29.117009623575573 29.87900813811248 29.44360444796216 29.90982154949809 28.14818775326632 29.918490262109078 27.987988907092056 29.613971062606375 28.483555015112444 29.59294928765438 29.314111833743528 29.996888991295148 28.41140763271043 29.91547738368713 28.268508643423644 29.686027073120734 29.00136638075205 30.34110008371767 29.38392897130775 29.695373085839858 29.107297249876844 30.120197823582643 28.744092617499128 29.975395716750175 516.0 514.0 610.0 775.0 424.0 857.0 564.0 840.0 538.0 772.0 716.0 615.0 555.0 820.0 420.0 844.0 767.0 743.0 748.0 720.0 640.0 740.0 538.0 895.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 4.0 5.0 6.0 6.0 5.0 5.0 5.0 5.0 5.0 5.0 -1.0378747260916725 3.225641456243767e-05 0.0005099643033035255 GO:0009117 nucleotide metabolic process biological_process 33.39873983605527 34.226354027542776 33.619084710997285 33.57809666544998 33.26702398250604 34.18296072108865 33.011954524733824 34.410136366663416 32.88388264171337 34.13552994554983 33.53275339163215 34.10257888220868 33.469659151638325 33.72705052752144 33.855954247134626 34.606639921209755 32.94986780877748 34.69632048507429 33.98381792654911 34.398650567851185 33.35545200494226 34.109612657814075 33.03147280364634 34.299172692237164 33.337599077448246 34.08065042559209 5241.0 5171.0 5230.0 6291.0 5812.0 8263.0 6433.0 7569.0 6631.0 7620.0 7129.0 5758.0 7250.0 7661.0 5782.0 7842.0 8936.0 8490.0 6670.0 6587.0 6821.0 7102.0 6947.0 7708.0 9.0 9.0 8.0 9.0 8.0 9.0 9.0 10.0 9.0 9.0 8.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 8.0 8.0 8.0 9.0 9.0 9.0 -0.8276141914875055 0.00010962068302139599 0.000648372570666835 GO:0009119 ribonucleoside metabolic process biological_process 27.28319383242872 28.41830145956717 27.647948685467405 28.411465866308518 27.83878918663541 28.41167927619853 26.57202332625293 28.43358760222002 26.48417225254373 28.10178695637207 26.91836470315562 28.11659106595617 27.813350107509237 28.5208398341982 26.872206728670978 28.43067080050239 26.76654496941205 28.22637443096204 27.021838700013053 28.87204580357933 27.790361180279163 28.18540049496261 27.531670792920284 28.58030585088663 27.19659025938307 28.53904756981996 188.0 186.0 224.0 287.0 150.0 314.0 203.0 305.0 197.0 285.0 261.0 225.0 194.0 304.0 154.0 315.0 266.0 258.0 273.0 265.0 230.0 276.0 197.0 329.0 4.0 3.0 3.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -1.1351076271384528 3.225641456243767e-05 0.0005099643033035255 GO:0009123 nucleoside monophosphate metabolic process biological_process 30.565440028596296 31.246029387447837 30.493431831982583 30.816920380266428 30.19469623592776 30.712918812115177 30.58709120489247 31.307544522012357 30.138393224213328 31.188860270431814 30.89431570356991 31.24236559810545 31.242923039068213 31.32658839159887 30.07037866736566 31.586579540515967 30.362129114562226 31.31440484629488 30.641751559373308 31.358038635526643 30.672240657480145 31.052842183878745 30.27374494434561 31.56021490900056 30.74792153372569 31.2360808915877 1423.0 1622.0 1322.0 1714.0 1570.0 2597.0 1593.0 2521.0 1843.0 2421.0 2282.0 2005.0 1866.0 2612.0 1843.0 2717.0 2080.0 2491.0 1716.0 2056.0 1826.0 2317.0 2178.0 2576.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 -0.6805893588515417 0.0002755038114342687 0.0011655212090507369 GO:0009124 nucleoside monophosphate biosynthetic process biological_process 28.584792629963413 29.270156217051223 28.50228821148128 28.830129038185788 28.205526697193307 28.72911270360176 28.59448339634875 29.33420496974243 28.15808593895461 29.21547126418217 28.90411956503776 29.263858708516523 29.259652205111127 29.342087455819588 28.09220720206648 29.602488450926433 28.3790192930975 29.35062295719675 28.69556820639854 29.37804841908587 28.70301688152028 29.07831424958416 28.29862953833065 29.58927545740912 28.7595264786138 29.27522942374526 359.0 412.0 333.0 434.0 395.0 661.0 403.0 640.0 464.0 616.0 574.0 512.0 475.0 665.0 467.0 692.0 530.0 634.0 436.0 524.0 460.0 591.0 549.0 655.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.6853635870878101 0.0001748865925420931 0.0008236168584623857 GO:0009126 purine nucleoside monophosphate metabolic process biological_process 28.650039158030648 29.420777498671278 28.673080401557414 29.12161403751769 28.523283250506616 28.966327123409826 28.83071553907195 29.52656211125733 28.238860020317002 29.296516954120392 28.958840217554982 29.281465820054663 29.431295367118164 29.488020256865195 28.123836683524136 29.853498097906872 28.42194499125564 29.50669685678935 28.531115338496708 29.609871487508663 28.418569595384284 29.279531462376536 28.418081644284463 29.574756813106642 28.72457466237081 29.327994649533032 393.0 438.0 420.0 492.0 417.0 666.0 399.0 639.0 496.0 603.0 604.0 480.0 451.0 728.0 465.0 696.0 546.0 660.0 474.0 582.0 466.0 549.0 544.0 666.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.7707383406406301 0.0001386794054294884 0.0007006959432226783 GO:0009129 pyrimidine nucleoside monophosphate metabolic process biological_process 27.310119965943045 27.70955089819573 27.008220444966124 26.81283564931491 26.09256625241725 26.923234267442734 26.889643914601074 27.60750411542181 26.83837871839839 27.846968609134933 27.72025092551404 28.08398646699929 27.698505245578453 27.863414625324477 26.879088067811473 27.74607302067892 27.17708097106153 27.666728207523278 27.689455933457303 27.559306950866088 28.003139008688198 27.330871626736368 26.83326114837591 28.427414378797607 27.757131200406494 27.887367957739 135.0 156.0 72.0 141.0 168.0 288.0 189.0 291.0 189.0 285.0 246.0 249.0 234.0 228.0 216.0 303.0 219.0 255.0 159.0 174.0 213.0 297.0 264.0 282.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.39943093225268456 0.0940685547103812 0.1379524750629327 GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process biological_process 25.72515746522189 26.12458839747458 25.423257944244966 25.227873148593755 24.50760375169609 25.33827176672157 25.304681413879923 26.022541614700646 25.253416217677234 26.262006108413768 26.13528842479289 26.499023966278127 26.113542744857288 26.27845212460333 25.29412556709032 26.161110519957766 25.592118470340377 26.081765706802123 26.104493432736145 25.97434445014493 26.418176507967054 25.74590912601521 25.248298647654767 26.84245187807645 26.172168699685344 26.30240545701784 45.0 52.0 24.0 47.0 56.0 96.0 63.0 97.0 63.0 95.0 82.0 83.0 78.0 76.0 72.0 101.0 73.0 85.0 53.0 58.0 71.0 99.0 88.0 94.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.3994309322526881 0.0940685547103812 0.1379524750629327 GO:0009132 nucleoside diphosphate metabolic process biological_process 29.951993020807 31.127013219192534 30.621317351526073 30.47156927306283 30.23348205127018 31.23201667321547 29.29261413018641 31.355283299499696 28.738619407291175 30.958610711229976 29.79005262750407 30.89585446173561 29.590883977166786 30.428683194995827 30.80123289712328 31.54178983728444 29.373818569922772 31.737792852294067 30.749089346994282 31.34123796600604 29.74711276445117 31.047803194694385 29.181917988283555 31.08604984950647 29.62004900435113 30.842980742144185 310.0 295.0 357.0 416.0 316.0 504.0 356.0 416.0 365.0 414.0 319.0 280.0 467.0 411.0 321.0 443.0 559.0 429.0 393.0 389.0 360.0 364.0 322.0 400.0 6.0 6.0 3.0 6.0 6.0 6.0 4.0 6.0 6.0 6.0 6.0 6.0 4.0 6.0 4.0 6.0 6.0 3.0 3.0 6.0 6.0 6.0 6.0 6.0 -1.1750201983855355 0.0001386794054294884 0.0007006959432226783 GO:0009133 nucleoside diphosphate biosynthetic process biological_process 19.179972647254683 20.837044293403547 20.461319077213698 20.32405250202081 NA 15.655482202387493 17.98519851724128 20.256299575659174 18.634001884482288 19.36479617618229 19.184706023369287 21.661377357482415 19.121261464324505 19.77132941386353 19.123676133161442 22.23362102706336 18.26040078504702 21.10121000182624 18.760994673592233 NA NA 17.632832424728793 18.901774229689238 21.970421617120614 19.6870616972378 20.616540424427928 4.0 4.0 NA 2.0 4.0 4.0 2.0 2.0 2.0 6.0 4.0 4.0 2.0 6.0 2.0 8.0 4.0 NA NA 2.0 2.0 4.0 4.0 4.0 4.0 4.0 NA 2.0 4.0 4.0 2.0 2.0 2.0 4.0 4.0 2.0 2.0 4.0 2.0 4.0 2.0 NA NA 2.0 2.0 4.0 4.0 4.0 -1.6570716461488644 0.034640469794189374 0.05922096753855936 GO:0009135 purine nucleoside diphosphate metabolic process biological_process 28.36573155793248 29.54060081391257 29.036166108793324 28.88655253775852 28.64851955054902 29.64693607295549 27.706175283710905 29.76804733235773 27.15431192418673 29.371779983024112 28.20138105499236 29.309187417590426 28.004445895821746 28.84014311112464 29.21649059600809 29.95518398776805 27.78562320001729 30.150306274253502 29.16270559016053 29.75627546528489 28.162150263730013 29.462312242059394 27.589292681683173 29.50009759450245 28.03325599897525 29.255885403370986 101.0 96.0 119.0 136.0 103.0 165.0 119.0 136.0 119.0 133.0 104.0 88.0 156.0 132.0 107.0 140.0 181.0 143.0 131.0 127.0 117.0 119.0 105.0 131.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 1.0 1.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 -1.174869255980088 0.0001386794054294884 0.0007006959432226783 GO:0009138 pyrimidine nucleoside diphosphate metabolic process biological_process 19.02531725304692 20.144564531475567 18.25413182631937 17.857152955096012 NA 16.24044470310865 18.02885325926526 20.558151061494442 NA 19.94975867690345 19.769668524090445 20.3529297020551 18.499448878315352 20.35629191458469 NA 20.93752738993089 NA 21.231165218940106 19.345957174313387 NA NA 18.217794925449947 19.4867367304104 20.201748880926466 18.900775199397707 20.21415204358713 3.0 3.0 NA 3.0 3.0 3.0 NA 3.0 3.0 6.0 3.0 6.0 NA 6.0 NA 9.0 6.0 NA NA 3.0 3.0 3.0 3.0 3.0 2.0 2.0 NA 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 NA 2.0 NA 2.0 2.0 NA NA 2.0 2.0 2.0 2.0 2.0 -1.1192472784286451 0.09383938076137766 0.1379524750629327 GO:0009141 nucleoside triphosphate metabolic process biological_process 32.224370897221114 33.299645623570164 32.64659655472789 32.61482883048229 32.27720199191079 33.332034406506274 31.63972337507689 33.48577414139699 31.37125254048531 33.17180367090245 32.148904081112086 33.16177051117529 32.083391923380844 32.67176257388765 32.79939575528128 33.72112764233343 31.73676769200431 33.84231411133922 32.9904595217862 33.44913923629533 32.26169457242334 33.197951551607325 31.82391679936436 33.33448601708208 32.0050633898001 33.123059810015114 2088.0 2016.0 2170.0 2748.0 2086.0 3174.0 2470.0 2944.0 2484.0 2856.0 2522.0 2090.0 2858.0 2802.0 2018.0 2904.0 3558.0 3188.0 2770.0 2604.0 2656.0 2550.0 2400.0 2994.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 5.0 6.0 6.0 6.0 6.0 6.0 5.0 6.0 6.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 -1.0752747263490505 0.00010962068302139599 0.000648372570666835 GO:0009142 nucleoside triphosphate biosynthetic process biological_process 30.008780576136544 31.067928928919244 30.389307309606362 30.377950636449512 30.019294088763946 31.085339299876555 29.43385281177316 31.2462902659147 29.200476890370666 30.94706342539388 29.946720151650876 30.947458092748732 29.89930569870986 30.449544726055606 30.53465716839128 31.492031577743848 29.53516828795539 31.59913596638709 30.7707840116901 31.20514692687449 30.082610103754106 30.961827015284506 29.660697511587344 31.115554317102397 29.807420569707627 30.90975641227191 472.0 454.0 480.0 614.0 462.0 704.0 554.0 662.0 560.0 646.0 578.0 474.0 632.0 630.0 450.0 650.0 796.0 718.0 626.0 582.0 602.0 574.0 548.0 680.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -1.0591483527826995 0.00010962068302139599 0.000648372570666835 GO:0009144 purine nucleoside triphosphate metabolic process biological_process 30.814407026568517 31.91314326220345 31.282165432567638 31.223552286603322 30.904364898566843 31.954875513779463 30.2410581920848 32.10495350534451 29.934741851138657 31.779414061975174 30.72472945866959 31.763138096179517 30.603801621071497 31.25886418814538 31.42939094539252 32.34174394665507 30.31862901362672 32.478054988773586 31.58663641091655 32.07126502616035 30.844798128555865 31.821785321462198 30.33806828045985 31.9113585894865 30.57062870260157 31.7317522222754 708.0 659.0 773.0 933.0 720.0 1073.0 852.0 959.0 833.0 920.0 781.0 652.0 1000.0 913.0 689.0 950.0 1158.0 1041.0 909.0 890.0 843.0 788.0 771.0 960.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 -1.0987362356349344 0.0001386794054294884 0.0007006959432226783 GO:0009147 pyrimidine nucleoside triphosphate metabolic process biological_process 26.25910514357024 26.800671449508663 25.494364592107374 26.315826868453808 25.53350530812694 26.639870253634605 25.28595615060349 26.85893594784741 25.671016747455106 26.80272126840391 26.40911129351192 26.892745551090666 27.089545158819238 26.81765605032177 26.00715338521847 26.920591994669504 25.867496263623337 26.450845019026023 26.90524933677073 26.755971384396204 26.20999329419934 26.341689535924512 26.82773226665573 27.66858765369616 26.43238016707589 26.61156743704977 100.0 122.0 72.0 134.0 89.0 162.0 105.0 182.0 129.0 185.0 191.0 156.0 112.0 173.0 95.0 177.0 223.0 194.0 163.0 121.0 184.0 200.0 155.0 197.0 3.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.5415663059384244 0.024343383653741054 0.04309296851045225 GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process biological_process 24.631815347260225 25.183970196028977 23.90322758220009 24.69207255384212 23.822429745207753 25.01140445751608 23.62079988893496 25.24221216137209 23.928548776478053 25.21139531824101 24.779689529039974 25.29371715955897 25.47039886971732 25.16124922900643 24.362997269253288 25.324335202531767 24.22350011500093 24.848418107573828 25.306537596715174 25.123544558454075 24.623519647987226 24.728919173504096 25.22582774746107 26.037606546171414 24.81549618745565 25.012059498335475 33.0 40.0 23.0 44.0 27.0 53.0 32.0 60.0 42.0 61.0 63.0 51.0 35.0 57.0 30.0 58.0 73.0 63.0 54.0 40.0 59.0 66.0 51.0 65.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.5521548487687511 0.024343383653741054 0.04309296851045225 GO:0009150 purine ribonucleotide metabolic process biological_process 31.22740207694745 32.03396604149692 31.43401223468398 31.368698071214904 31.072713587994407 32.0088937270166 30.840680850523015 32.2232396919852 30.801592857132594 31.941760136845414 31.366969554901825 31.878443350699172 31.271896179857503 31.477156431959767 31.759814139908123 32.44057994846757 30.775455983361912 32.550724657850765 31.785157639401692 32.219866956581875 31.072264347697285 31.93460416185105 30.889207918744606 32.031497442257574 31.179080228491287 31.890271486806 1004.0 937.0 1072.0 1213.0 1141.0 1570.0 1282.0 1375.0 1300.0 1365.0 1320.0 998.0 1430.0 1460.0 1098.0 1442.0 1714.0 1595.0 1287.0 1287.0 1278.0 1216.0 1287.0 1396.0 9.0 9.0 10.0 10.0 10.0 10.0 11.0 11.0 10.0 11.0 11.0 10.0 11.0 9.0 11.0 9.0 11.0 11.0 10.0 10.0 11.0 10.0 11.0 11.0 -0.8065639645494684 0.00010962068302139599 0.000648372570666835 GO:0009152 purine ribonucleotide biosynthetic process biological_process 29.57195706142136 30.354120621041325 29.691755615036417 29.717011105147915 29.34504852198965 30.28218804032761 29.25631955212257 30.52542234558999 29.22736657488653 30.24851640036922 29.763336173060303 30.231946806858808 29.714534231668033 29.873069428964147 29.975623054939064 30.776639362449853 29.141174465436176 30.826745406654506 30.081919341050586 30.515643564625893 29.46689910890088 30.247647988721162 29.304136103600122 30.38610316130075 29.53264309516053 30.22951254379516 372.0 360.0 390.0 451.0 416.0 583.0 465.0 523.0 473.0 517.0 501.0 385.0 507.0 557.0 403.0 549.0 608.0 599.0 470.0 487.0 466.0 456.0 482.0 541.0 7.0 7.0 7.0 7.0 8.0 8.0 9.0 8.0 7.0 9.0 10.0 7.0 9.0 7.0 9.0 7.0 8.0 8.0 7.0 7.0 9.0 8.0 10.0 9.0 -0.7821635596199634 0.00010962068302139599 0.000648372570666835 GO:0009156 ribonucleoside monophosphate biosynthetic process biological_process 27.60101301326688 28.316867021971092 27.51876263366809 27.857829869305 27.22482313030473 27.761246646455533 27.59324256685709 28.385617805725733 27.160625839269525 28.26619659073925 27.89666598012621 28.305465488293372 28.25403065405923 28.37434467681978 27.118188851282767 28.631833169034834 27.388047126662197 28.42056155407988 27.78841590303269 28.413406588519663 27.74610996804691 28.127862693213093 27.31105553093264 28.647355228784395 27.75508734760519 28.349300359358157 180.0 214.0 168.0 221.0 194.0 342.0 200.0 328.0 228.0 317.0 280.0 268.0 242.0 344.0 233.0 359.0 269.0 324.0 222.0 271.0 225.0 307.0 271.0 336.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 -0.7158540087042127 0.0001386794054294884 0.0007006959432226783 GO:0009161 ribonucleoside monophosphate metabolic process biological_process 29.134139031731767 29.838726982894038 29.08025796587943 29.407980185290512 28.781111751630373 29.30358942164961 29.15839060647625 29.90095119994273 28.69256023138684 29.781627150795412 29.45501106342021 29.83406844971125 29.79338344530177 29.918535806444503 28.643721689061056 30.175129682609512 28.92781040342206 29.911670498119665 29.23484821265017 29.94571154448123 29.250026918903675 29.64625648930141 28.82880766771925 30.15667669746961 29.30834144342103 29.83294931861534 527.0 616.0 494.0 641.0 572.0 979.0 581.0 945.0 670.0 908.0 825.0 761.0 691.0 985.0 674.0 1026.0 767.0 927.0 638.0 773.0 660.0 874.0 794.0 964.0 4.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 3.0 3.0 3.0 4.0 4.0 4.0 -0.7045879511622708 0.0001748865925420931 0.0008236168584623857 GO:0009162 deoxyribonucleoside monophosphate metabolic process biological_process 23.18559696389966 20.202118604710915 19.597545081989555 NA 19.402797600901565 19.34191795376936 22.683710560620586 19.064300860837093 23.483437992664552 19.564928133413147 23.80087735523129 20.585578398777113 24.651214625284165 19.08855963719049 22.505595402137512 21.06341469936423 23.096503979862536 NA 22.071377908206525 21.7333512533798 22.894189843306346 15.660916039394536 23.619139096813523 20.168206171497392 23.69266794979621 19.98180801262436 9.0 NA 3.0 6.0 18.0 3.0 21.0 6.0 24.0 9.0 33.0 3.0 15.0 6.0 21.0 NA 18.0 15.0 9.0 3.0 27.0 6.0 27.0 9.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.9834783591887444 0.0012337333969834146 0.003737134173386654 GO:0009163 nucleoside biosynthetic process biological_process 26.53175680482501 27.847995694689995 27.096184627550315 27.92385905713574 27.06755837062385 27.90667399008717 25.80379309620807 27.8549953125082 25.653318818421244 27.55935692714269 26.18176773602595 27.488036486014586 27.118059410410794 27.995366503023323 26.215748244825505 27.873521539782324 25.918647517186688 27.534865983918642 26.358274397023358 28.232939417943285 27.01491731938641 27.639219504019927 26.561732807100093 28.189056928878017 26.33941401925497 27.749044547175718 112.0 138.0 125.0 166.0 95.0 184.0 114.0 185.0 116.0 172.0 146.0 139.0 124.0 179.0 92.0 184.0 164.0 168.0 154.0 164.0 120.0 168.0 105.0 195.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.3162388898649837 3.225641456243767e-05 0.0005099643033035255 GO:0009164 nucleoside catabolic process biological_process 21.60364574305156 22.49620332270069 20.94113959091284 18.198905103441547 15.333980246519134 16.715179479142186 19.866082892287206 23.165177365284734 21.407705447448528 23.682180084062534 20.991585088357645 23.11385109611605 22.45129916372709 21.940440126713533 21.44200406399007 22.017960072508718 20.610730671753284 22.92600702872103 22.063769173232174 22.18131467792417 21.06805760065568 21.45912099349611 23.1995440267992 22.043376450598373 21.918300704157637 23.31540747387539 10.0 1.0 1.0 1.0 6.0 21.0 14.0 27.0 11.0 21.0 16.0 14.0 5.0 16.0 7.0 20.0 15.0 18.0 8.0 7.0 17.0 13.0 15.0 24.0 2.0 NA NA NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.8925575796491323 0.06467168750236378 0.10076188015349562 GO:0009165 nucleotide biosynthetic process biological_process 31.168471866335587 31.95765198837717 31.325122470943466 31.3223394309482 30.939914328076032 31.87110187727091 30.87179628833114 32.12014553399125 30.689271539951548 31.882704441525426 31.359150332410998 31.876269016159394 31.320765614779138 31.51465802610713 31.495774086578827 32.32442589651226 30.747791203498483 32.379536026469694 31.72403037305803 32.105998805325704 31.20037492405377 31.828883536929286 30.83122998121288 32.092834455726354 31.11301808219821 31.829161314342016 1252.0 1248.0 1198.0 1477.0 1374.0 1914.0 1513.0 1806.0 1574.0 1846.0 1728.0 1387.0 1674.0 1829.0 1384.0 1876.0 2078.0 2037.0 1562.0 1553.0 1629.0 1733.0 1674.0 1876.0 7.0 7.0 6.0 7.0 6.0 7.0 7.0 8.0 7.0 7.0 6.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 6.0 6.0 6.0 7.0 7.0 7.0 -0.7891801220415822 0.00010962068302139599 0.000648372570666835 GO:0009166 nucleotide catabolic process biological_process 28.49857370518829 29.640444824647172 29.146571530861234 29.02798898400515 28.973677610105057 29.74143710929271 27.822547952016865 29.92816823071932 27.26978997108525 29.472103227185173 28.235389251750213 29.3614540873387 28.09273591793081 28.957694852371965 29.285998306822552 30.03710668850152 27.830759232644805 30.208997645584716 29.344428724558462 29.90046342604497 28.342166088670297 29.543172384612603 27.65992651950777 29.571039426309923 28.16428877784705 29.373136475203232 131.0 124.0 163.0 172.0 131.0 210.0 136.0 174.0 139.0 163.0 124.0 119.0 177.0 158.0 122.0 172.0 237.0 192.0 171.0 158.0 137.0 153.0 130.0 165.0 2.0 2.0 2.0 2.0 4.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.1418711194588838 0.0001748865925420931 0.0008236168584623857 GO:0009167 purine ribonucleoside monophosphate metabolic process biological_process 28.06524125281845 28.835795381630174 28.08811790083625 28.536651536796533 27.938320749785465 28.38136462268867 28.245753038350788 28.941599610536176 27.653897519595837 28.711554453399238 28.374009470612783 28.6965033193335 28.84657804152021 28.903057756144037 27.539980963733047 29.26836119167623 27.83698249053448 28.921734356068196 27.946152837775553 29.02490898678751 27.83360709466313 28.694568961655374 27.83342772117727 28.989794312385484 28.13995309583123 28.743032148811878 262.0 292.0 280.0 328.0 278.0 444.0 266.0 426.0 331.0 402.0 403.0 320.0 301.0 485.0 310.0 464.0 364.0 440.0 316.0 388.0 311.0 366.0 363.0 444.0 4.0 4.0 4.0 4.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 4.0 5.0 4.0 5.0 4.0 5.0 5.0 5.0 4.0 5.0 4.0 5.0 5.0 -0.7705541288117246 0.0001386794054294884 0.0007006959432226783 GO:0009168 purine ribonucleoside monophosphate biosynthetic process biological_process 27.064747409945284 27.835854229789877 27.08811790083625 27.536651536796533 26.93832074978546 27.38136462268867 27.245753038350788 27.94159961053618 26.653897519595837 27.711554453399238 27.37361417317327 27.696503319333505 27.845842391118197 27.903057756144037 26.536658070440197 28.268884344966462 26.83698249053448 27.921734356068196 26.94615283777556 28.024908986787505 26.83360709466313 27.694568961655374 26.832501790260032 27.989794312385484 27.138930051485037 27.743032148811878 131.0 146.0 140.0 164.0 139.0 222.0 133.0 213.0 165.0 201.0 201.0 160.0 150.0 243.0 155.0 232.0 182.0 220.0 158.0 194.0 155.0 183.0 181.0 222.0 3.0 3.0 3.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 3.0 4.0 3.0 4.0 4.0 -0.7711068198445936 0.0001386794054294884 0.0007006959432226783 GO:0009173 pyrimidine ribonucleoside monophosphate metabolic process biological_process 26.639979576503826 27.11796581464353 26.414754041146068 26.227873148593755 25.49356057030096 26.330718979781174 26.224309662032336 27.018669066370958 26.105034994958682 27.257363837574268 27.036640272862282 27.491023183638138 26.92752868201241 27.27515468994195 26.22278852254475 27.14699761536352 26.50422417026763 27.081765706802123 27.07481617623213 26.94868522754935 27.375753917593823 26.74546629859023 26.08380427744277 27.837735432466435 27.08325613655839 27.296376099235648 84.0 104.0 46.0 90.0 100.0 190.0 112.0 190.0 110.0 184.0 142.0 164.0 146.0 148.0 130.0 202.0 134.0 160.0 100.0 114.0 124.0 194.0 158.0 182.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.4779862381397031 0.024343383653741054 0.04309296851045225 GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process biological_process 22.6006344631785 19.61715610398976 19.012582581268397 NA 18.817835100180407 18.7569554530482 22.098748059899425 18.479338360115946 22.898475491943394 18.97996563269199 23.21591485451014 20.000615898055955 24.06625212456301 18.503597136469327 21.920632901416358 20.478452198643073 22.511541479141393 NA 21.48641540748537 21.14838875265864 22.309227342585178 15.075953538673375 23.034176596092358 19.583243670776234 23.107705449075056 19.3968455119032 6.0 NA 2.0 4.0 12.0 2.0 14.0 4.0 16.0 6.0 22.0 2.0 10.0 4.0 14.0 NA 12.0 10.0 6.0 2.0 18.0 4.0 18.0 6.0 3.0 NA 2.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 3.0 NA 3.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 2.983478359188741 0.0012337333969834146 0.003737134173386654 GO:0009179 purine ribonucleoside diphosphate metabolic process biological_process 28.365131946608816 29.5396687339527 29.034546583451643 28.884873652201236 28.64851955054902 29.64693607295549 27.70590784856141 29.767871249913693 27.15234597848051 29.371779983024112 28.20138105499236 29.306556322132145 28.00357978749721 28.84014311112464 29.215829896336835 29.952692056522174 27.78464390336133 30.149937884595513 29.16270559016053 29.75627546528489 28.162150263730013 29.462312242059394 27.589292681683173 29.496954170031827 28.03189559133705 29.254988581689314 100.0 95.0 119.0 136.0 102.0 164.0 118.0 136.0 119.0 132.0 103.0 88.0 155.0 131.0 106.0 139.0 181.0 143.0 131.0 127.0 117.0 118.0 104.0 130.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 1.0 1.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 -1.1745367873438823 0.0001386794054294884 0.0007006959432226783 GO:0009185 ribonucleoside diphosphate metabolic process biological_process 28.36573155793248 29.54060081391257 29.036166108793324 28.88655253775852 28.64851955054902 29.64693607295549 27.706175283710905 29.76804733235773 27.15431192418673 29.371779983024112 28.20138105499236 29.309187417590426 28.004445895821746 28.84014311112464 29.21649059600809 29.95518398776805 27.78562320001729 30.150306274253502 29.16270559016053 29.75627546528489 28.162150263730013 29.462312242059394 27.589292681683173 29.50009759450245 28.03325599897525 29.255885403370986 101.0 96.0 119.0 136.0 103.0 165.0 119.0 136.0 119.0 133.0 104.0 88.0 156.0 132.0 107.0 140.0 181.0 143.0 131.0 127.0 117.0 119.0 105.0 131.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 1.0 1.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 -1.174869255980088 0.0001386794054294884 0.0007006959432226783 GO:0009186 deoxyribonucleoside diphosphate metabolic process biological_process 19.02531725304692 20.144564531475567 18.25413182631937 17.857152955096012 NA 16.24044470310865 18.02885325926526 20.558151061494442 NA 19.94975867690345 19.769668524090445 20.3529297020551 18.499448878315352 20.35629191458469 NA 20.93752738993089 NA 21.231165218940106 19.345957174313387 NA NA 18.217794925449947 19.4867367304104 20.201748880926466 18.900775199397707 20.21415204358713 3.0 3.0 NA 3.0 3.0 3.0 NA 3.0 3.0 6.0 3.0 6.0 NA 6.0 NA 9.0 6.0 NA NA 3.0 3.0 3.0 3.0 3.0 2.0 2.0 NA 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 NA 2.0 NA 2.0 2.0 NA NA 2.0 2.0 2.0 2.0 2.0 -1.1192472784286451 0.09383938076137766 0.1379524750629327 GO:0009199 ribonucleoside triphosphate metabolic process biological_process 30.86739891520483 31.94907141621343 31.305347535595565 31.26185979421605 30.932034572273146 31.985797209204783 30.28063084064011 32.1389932481636 29.99719414347677 31.820678045966233 30.785243755482554 31.807699181841866 30.70389614839432 31.31206320073189 31.460944639097363 32.37050680193888 30.378061619083084 32.49658344400209 31.639159589833397 32.10056515667023 30.89710100204185 31.85067864387465 30.44367719434551 31.97836926921237 30.6399516476625 31.76756395054413 782.0 735.0 822.0 1030.0 781.0 1197.0 935.0 1102.0 935.0 1051.0 923.0 754.0 1096.0 1035.0 773.0 1070.0 1348.0 1178.0 1050.0 982.0 990.0 941.0 885.0 1109.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.081672501008601 0.00010962068302139599 0.000648372570666835 GO:0009200 deoxyribonucleoside triphosphate metabolic process biological_process 23.16846170896346 23.573015303571506 22.161534127425337 23.82443421466401 23.071153963792394 22.999422530562768 22.35763877431399 22.951033209669053 22.92965007771637 22.820546829701872 23.642901332947197 23.22275586770509 24.583438444341684 24.230302135163804 21.49867401813441 23.774209770152332 22.22504962034492 23.485287501226182 22.427707738234957 24.173011943479448 22.61582698129183 22.453896945965766 23.93409231292264 24.24167561992272 23.52412343898393 23.382713031939698 25.0 41.0 21.0 29.0 26.0 24.0 21.0 29.0 27.0 50.0 47.0 48.0 13.0 41.0 11.0 45.0 31.0 47.0 22.0 19.0 37.0 38.0 41.0 41.0 2.0 2.0 2.0 2.0 4.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.4045535946080463 0.0832645166635504 0.12534875367444018 GO:0009201 ribonucleoside triphosphate biosynthetic process biological_process 29.002498367651395 30.063677499368385 29.386233781549848 29.369212310889136 29.015092012385782 30.08310900131046 28.430685178075986 30.24422780982676 28.196630524794674 29.943857656665593 28.93702678823719 29.94346719628079 28.878218158922216 29.44035467866907 29.534501372445284 30.487772099454908 28.532138879935705 30.59598691992438 29.76844610181945 30.19921122023909 29.07723185386615 29.959930335002074 28.64401361815204 30.11011239403121 28.797063401012146 29.905024518978664 228.0 214.0 234.0 298.0 227.0 345.0 273.0 322.0 272.0 307.0 274.0 222.0 314.0 302.0 223.0 311.0 389.0 345.0 306.0 285.0 291.0 275.0 261.0 327.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.0611791317169903 0.00010962068302139599 0.000648372570666835 GO:0009205 purine ribonucleoside triphosphate metabolic process biological_process 30.355527546342607 31.460114091736692 30.84117514491039 30.77364417063141 30.462600478746037 31.506804030163888 29.774353810608744 31.655146096118337 29.45067988794397 31.32340209986693 30.260078277019854 31.30332963396182 30.13265697216312 30.80180036324355 30.99177545073365 31.887130211308666 29.852973949519228 32.02938458125388 31.13000365988404 31.623905063823447 30.36806394309741 31.37008358920345 29.85662161557175 31.45471208988189 30.104536910431772 31.270005439067802 504.0 467.0 554.0 662.0 508.0 760.0 606.0 678.0 595.0 654.0 553.0 460.0 716.0 645.0 494.0 671.0 831.0 735.0 650.0 629.0 601.0 558.0 548.0 678.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.1045865453940849 0.0001386794054294884 0.0007006959432226783 GO:0009206 purine ribonucleoside triphosphate biosynthetic process biological_process 28.937619333360363 30.0182220362749 29.35675435009856 29.320781574424768 28.979414456584788 30.041858651821734 28.38159599736913 30.200617936325177 28.123796109758892 29.891871296134344 28.86408755291102 29.888974801882227 28.758713871469396 29.373752101062433 29.49406472175693 30.45132586759711 28.46062568412695 30.57209013032108 29.703898691528412 30.161900242731644 29.01547966003207 29.922944752253066 28.52071464575551 30.02749469512555 28.71377118014113 29.86052874094799 203.0 187.0 217.0 263.0 204.0 299.0 245.0 271.0 238.0 262.0 226.0 186.0 281.0 258.0 195.0 267.0 325.0 296.0 259.0 251.0 242.0 221.0 223.0 275.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.0806027029145362 0.00010962068302139599 0.000648372570666835 GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process biological_process 25.49531020031661 26.05284057483191 24.758605302260595 25.448365062563525 24.659684216476112 25.934316749870504 24.52899270905305 26.17451004230892 24.85236426171593 26.12345312480382 25.594783330976615 26.189739079985326 26.22524636184417 25.97013695134022 25.35737121403022 26.162734447570877 25.162116894815878 25.668249268540567 26.254029375652717 25.907573531934556 25.500333717327308 25.655817495385794 26.03426948278284 26.942828988315 25.64117684834341 25.86387970066297 50.0 54.0 34.0 70.0 46.0 92.0 56.0 102.0 68.0 90.0 96.0 72.0 66.0 88.0 56.0 88.0 128.0 98.0 94.0 68.0 98.0 108.0 76.0 104.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.5575303745153022 0.02092133533779403 0.038284203081476474 GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process biological_process 24.49531020031661 25.05284057483191 23.758605302260595 24.448365062563525 23.659684216476112 24.93431674987051 23.52899270905305 25.17451004230892 23.85236426171593 25.12345312480382 24.594783330976615 25.189739079985326 25.22524636184417 24.97013695134022 24.35737121403022 25.162734447570877 24.162116894815878 24.668249268540567 25.254029375652717 24.907573531934556 24.500333717327308 24.655817495385794 25.03426948278284 25.942828988315 24.64117684834341 24.86387970066297 25.0 27.0 17.0 35.0 23.0 46.0 28.0 51.0 34.0 45.0 48.0 36.0 33.0 44.0 28.0 44.0 64.0 49.0 47.0 34.0 49.0 54.0 38.0 52.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.5575303745153022 0.02092133533779403 0.038284203081476474 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process biological_process 22.72181493578083 23.12806578315572 21.607282678265747 23.343261075035286 22.78561200888633 22.659605696631203 21.808593968142596 22.58444855176393 22.61926834829929 22.284903379825735 23.199669123411827 22.724235025225692 24.09137488441239 23.840921786926927 21.28321886625432 23.23821326708217 21.96240450422546 22.966578585519834 21.987643538134307 23.72155858089072 22.03995589823685 22.059606057044586 23.410393938568873 23.881766019264308 23.0530482163571 22.864044634740626 17.0 28.0 15.0 20.0 15.0 17.0 16.0 20.0 19.0 34.0 32.0 33.0 10.0 28.0 9.0 31.0 22.0 33.0 15.0 13.0 27.0 26.0 28.0 28.0 3.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.4062508473748885 0.0940685547103812 0.1379524750629327 GO:0009218 pyrimidine ribonucleotide metabolic process biological_process 27.50223094231357 27.958990514748567 27.18297398366746 27.13584594834928 26.523200392494985 27.439021748902906 26.95622578330586 27.921244846932 26.92908192584518 28.099485332055764 27.83357210429609 28.288869926664557 27.87702719249793 28.01337481912217 27.03580009933582 27.962662127216625 27.265988715742296 27.794230940478396 28.09683967742107 27.823724242192412 28.18445602028409 27.631893658715825 27.32845288229445 28.72758969565751 27.771737633135746 28.042701192818487 163.0 179.0 99.0 186.0 177.0 305.0 200.0 320.0 210.0 315.0 274.0 254.0 241.0 261.0 219.0 324.0 306.0 298.0 229.0 204.0 263.0 342.0 273.0 321.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.4567595724349971 0.03266344168491133 0.055917661485280296 GO:0009219 pyrimidine deoxyribonucleotide metabolic process biological_process 23.68486832596466 23.330163180981454 21.906861318781253 23.364561593974447 22.87499038040202 22.7634767310915 22.992118696850433 22.87341484093645 23.765615832585762 22.587429591257767 24.25151411904183 23.080650686476368 25.08889057953975 23.95767420466165 22.63684615148352 23.597688995589852 23.26294421383109 23.22987181195661 22.846286874527173 23.945641582892733 23.180864785183463 22.136023890327667 24.269875306894733 24.02297768319048 24.1069278329314 23.12303653270175 25.0 30.0 17.0 26.0 29.0 21.0 30.0 26.0 37.0 44.0 56.0 39.0 20.0 36.0 23.0 37.0 38.0 43.0 21.0 17.0 47.0 32.0 48.0 36.0 6.0 4.0 4.0 5.0 7.0 5.0 6.0 5.0 6.0 6.0 6.0 5.0 5.0 5.0 5.0 4.0 6.0 5.0 5.0 5.0 6.0 5.0 6.0 6.0 0.3547051449832068 0.5253727863737021 0.6008633207515945 GO:0009220 pyrimidine ribonucleotide biosynthetic process biological_process 26.7665907558016 27.191589231461553 26.477600433589238 26.345733483163308 25.82813410963859 26.68239638117262 26.23358527396327 27.144165328704442 26.189820187066694 27.348007202551074 27.11163292033979 27.54152068950345 27.0960444997087 27.224889105046078 26.19721684568616 27.15758665754987 26.501828951370612 27.00913720492332 27.39408579693357 27.07444376604462 27.53326482211069 26.900768393326654 26.555235644880558 27.954230474006614 26.974781265318647 27.28518031414251 96.0 100.0 59.0 106.0 104.0 164.0 116.0 174.0 121.0 178.0 155.0 136.0 135.0 143.0 126.0 179.0 175.0 169.0 132.0 113.0 152.0 191.0 156.0 178.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.42499847565995097 0.03766692222862868 0.06276144050911694 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process biological_process 22.424907411818943 21.93195824682357 20.830826299625805 22.033240896479764 20.79035864333427 20.93662612264729 21.57780506059105 21.263166977765998 22.173580203753247 21.464387869093105 23.041620977664447 21.86928625087916 23.946941522680937 22.33447221163277 20.980416626297593 22.48047579715757 21.859693434528904 22.05819098332749 21.598023947390434 22.57414680445384 22.1684825293296 20.509542321447704 23.16712503983624 22.302969199837023 22.93931710294791 21.950701905835245 12.0 14.0 7.0 12.0 11.0 9.0 11.0 12.0 17.0 21.0 27.0 18.0 7.0 17.0 9.0 17.0 17.0 19.0 10.0 8.0 20.0 15.0 23.0 17.0 4.0 2.0 2.0 3.0 4.0 3.0 3.0 3.0 5.0 4.0 5.0 3.0 2.0 3.0 3.0 2.0 4.0 3.0 4.0 3.0 5.0 3.0 5.0 4.0 0.4929491649953732 0.6441672226837103 0.7073013587238495 GO:0009225 nucleotide-sugar metabolic process biological_process 25.329775802972463 25.37488814149875 25.56227768318172 24.695472089318447 24.781093123796573 25.195555805128173 24.770898845531374 25.537307829652505 24.52639946677137 25.530713956266656 25.91703621382586 25.539322191160693 25.826566225384173 25.292442348778092 24.30726752041297 25.367480164328107 25.083348032483226 25.587629800780725 25.704047596531982 25.680150053545212 25.60124267651053 25.346941959169946 25.131785941937647 25.084065225278298 25.670009383996238 25.38410089953059 45.0 30.0 29.0 43.0 49.0 69.0 57.0 66.0 82.0 73.0 80.0 42.0 49.0 49.0 62.0 65.0 108.0 69.0 79.0 55.0 67.0 61.0 74.0 69.0 6.0 5.0 5.0 5.0 6.0 7.0 5.0 6.0 7.0 6.0 6.0 7.0 6.0 6.0 6.0 7.0 7.0 8.0 7.0 6.0 6.0 6.0 7.0 7.0 -0.04511233852628749 0.9539596927720386 0.9577970205788449 GO:0009226 nucleotide-sugar biosynthetic process biological_process 23.762772746282767 23.321700305537096 22.7469275671998 21.58416951232796 20.689091628297465 22.78650416495432 23.52488847560405 23.637564360066772 23.231466902099253 24.00956044857825 24.514452228505693 23.650825943706213 24.57034731355045 22.86857579389525 22.38807817029691 23.26130673119061 23.713761299662124 23.64198784300619 24.44524945496481 23.387106135247393 23.97070495947207 22.90480132713481 23.69129440358878 22.951658695930572 24.194589984652637 23.797758634986554 14.0 9.0 6.0 15.0 21.0 26.0 22.0 26.0 32.0 29.0 34.0 15.0 19.0 16.0 26.0 25.0 47.0 27.0 31.0 17.0 29.0 24.0 31.0 30.0 4.0 3.0 3.0 3.0 4.0 5.0 3.0 4.0 5.0 4.0 4.0 5.0 4.0 4.0 4.0 5.0 5.0 6.0 5.0 4.0 4.0 4.0 5.0 5.0 0.4410724407456712 0.2253456937016668 0.2954111614912607 GO:0009228 thiamine biosynthetic process biological_process 19.110943891049867 22.01100217926914 17.90148763795205 22.33391858748233 16.389452525881946 21.580335138537663 18.61445642242781 22.222966505011268 19.134685954222068 21.695860630982718 19.661894798079114 22.04439207665596 NA 22.02129940845996 NA 22.61997263298181 14.075947234298216 21.598423533799334 20.543627455929318 21.770773673455068 15.491946765369873 21.072140833200493 19.51638005868707 23.045299070836233 20.174178917612675 20.375196920842377 2.0 10.0 1.0 10.0 4.0 11.0 4.0 6.0 5.0 11.0 NA 12.0 NA 16.0 1.0 9.0 8.0 10.0 1.0 4.0 4.0 18.0 5.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.900058288219274 0.0001001018863854839 0.000648372570666835 GO:0009236 cobalamin biosynthetic process biological_process 24.442434188131326 24.192710490332498 20.24408386987439 21.951435368800983 24.38905640104634 22.492950521921873 23.53391835848555 25.051685984470524 24.27263880957069 25.317576163279792 24.984817960467787 24.273945015921413 24.781545188749906 22.877412274275546 24.11831499267181 24.519493956822576 24.217506674652785 24.491081810131174 23.99565703574036 24.207588269890948 23.293957878166466 23.522153704128375 25.936690264329357 23.128693694303852 24.684154481687933 24.704115733046606 7.0 9.0 5.0 12.0 33.0 54.0 41.0 52.0 36.0 31.0 56.0 21.0 44.0 29.0 40.0 43.0 47.0 44.0 27.0 26.0 49.0 30.0 60.0 38.0 NA NA NA NA NA NA NA NA NA 1.0 1.0 NA NA 1.0 NA NA NA 1.0 NA NA NA NA NA NA 0.24972369779882797 0.6861059569955559 0.7413508522341591 GO:0009245 lipid A biosynthetic process biological_process 22.36476187524207 23.097854325772314 22.310330225969828 21.347442646333924 22.50343112489116 23.951832795456337 21.161785032550245 22.953218166452245 22.700077354294528 22.902216172895088 22.074634287851925 22.842963278877697 22.443168577281632 23.08142551508465 22.67220730923078 23.754670297648342 21.961277429181038 23.43349268951045 22.973569475259584 22.043144776103524 21.36794420873238 23.146050052218126 22.871711775241288 23.66246373728001 22.25343308038265 21.97094623300727 6.0 5.0 5.0 20.0 8.0 8.0 13.0 8.0 10.0 8.0 13.0 6.0 10.0 13.0 8.0 8.0 17.0 12.0 4.0 10.0 13.0 8.0 9.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7330924505302434 0.024343383653741054 0.04309296851045225 GO:0009249 protein lipoylation biological_process 21.435826683631785 22.27548256371294 20.9966945375052 20.852967739396206 23.29955832668919 24.393103650141875 17.047265995732268 21.309803400983032 NA 21.125298268746945 18.768738379571094 20.928964722289862 21.85800306668987 22.571589076078638 18.406997899175032 22.680072983874144 NA 21.304999171195927 21.053694328996748 20.96992368346332 22.434577029666773 22.102814112894727 21.635084918803052 22.772135140872656 16.848657019796192 19.69116355141251 4.0 4.0 10.0 14.0 1.0 5.0 NA 4.0 3.0 6.0 4.0 5.0 2.0 7.0 NA 8.0 6.0 5.0 2.0 5.0 4.0 6.0 2.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8396558800811569 0.21027016591419945 0.27798428714080603 GO:0009252 peptidoglycan biosynthetic process biological_process 22.755788590889072 24.185242439725275 22.904882578232584 23.80291026256069 23.102518957541946 23.382477586456947 21.879451910615305 24.869206867872485 22.70004039627716 24.05787829752453 22.564422203052878 24.58951581488689 23.06209284430373 24.974801510024253 23.027481059153395 24.00542256555277 22.801951010872827 23.274156288107378 23.17973794286904 24.087615697278558 21.915973027507853 23.72066351479864 22.09978849575082 24.776704604162997 23.04929107187214 23.199347219798398 13.0 21.0 16.0 19.0 14.0 27.0 13.0 31.0 17.0 27.0 22.0 28.0 14.0 28.0 14.0 22.0 28.0 29.0 16.0 25.0 16.0 28.0 23.0 23.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.4294538488362036 3.225641456243767e-05 0.0005099643033035255 GO:0009259 ribonucleotide metabolic process biological_process 31.752072569258342 32.526364941494236 31.90281635110464 31.857219734688787 31.52796355576313 32.4627105080795 31.36896820073288 32.696910950236614 31.333139504423087 32.44806008118158 31.920961671065932 32.41730148931078 31.847372532613484 32.03657852994334 32.19221266585154 32.91205310420239 31.323142733438228 32.99562064272091 32.303519860347144 32.68763127931067 31.7043390467306 32.411532863642734 31.442701924120364 32.598801893746966 31.73310500517715 32.403216458508574 1637.0 1588.0 1620.0 1960.0 1838.0 2628.0 2069.0 2394.0 2106.0 2385.0 2250.0 1791.0 2317.0 2437.0 1848.0 2496.0 2803.0 2667.0 2118.0 2091.0 2159.0 2219.0 2202.0 2440.0 4.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 3.0 3.0 3.0 4.0 4.0 4.0 -0.7742923722358945 0.0001386794054294884 0.0007006959432226783 GO:0009260 ribonucleotide biosynthetic process biological_process 29.76512597838214 30.507848633989433 29.84012200769413 29.851745223802038 29.46587568784545 30.397615110211113 29.42373614195325 30.657861896569408 29.39408818426314 30.42991858122873 29.977076376880692 30.44141139360087 29.93218448820135 30.08967063104669 30.077429948206746 30.89034435993361 29.35610882717257 30.92568505116559 30.290057419660396 30.64341651949348 29.80234682716039 30.38290094249457 29.504218831104993 30.634420406053906 29.759418782785698 30.40599843933485 469.0 466.0 449.0 559.0 520.0 750.0 584.0 698.0 595.0 700.0 656.0 530.0 644.0 708.0 530.0 729.0 783.0 771.0 602.0 600.0 618.0 654.0 640.0 721.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 -0.7427226556072917 0.00010962068302139599 0.000648372570666835 GO:0009262 deoxyribonucleotide metabolic process biological_process 25.947499690427108 26.278237191346587 25.667801213005863 26.17146234542344 26.81604430305573 26.13835372130491 25.375244607021536 26.926991475424714 25.209593587433023 26.01436354151241 25.633946523082706 25.595103378096734 26.526117670754967 26.039146205856014 25.374180809648013 26.487244029989416 25.35168728422245 26.13202118461502 26.28768710713405 26.90616933031681 26.26868957049794 25.775565381171702 25.78858187985737 26.266263865178534 25.997755655090323 26.26461421976705 84.0 93.0 77.0 91.0 91.0 95.0 79.0 99.0 101.0 131.0 140.0 112.0 62.0 101.0 68.0 110.0 124.0 139.0 92.0 71.0 117.0 105.0 131.0 114.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.3307375009194793 0.10596880912720232 0.15148805703407617 GO:0009264 deoxyribonucleotide catabolic process biological_process 24.89197637634512 25.755766632740368 25.4052728729268 25.655368257603172 26.66011617842811 25.76116398849789 24.080066480270947 26.68180833785717 23.484556098077878 25.57619371359007 22.408305375578653 24.679356771374678 23.88707888444882 25.236061823233428 24.88851890714045 25.975174938611477 22.56130716405125 25.538285261503376 25.948760748365675 26.451392292528833 25.13912294528271 25.34573732801721 22.854416468524203 25.346042360643 24.633067772631787 25.69604749163209 30.0 31.0 43.0 35.0 27.0 48.0 18.0 38.0 18.0 29.0 20.0 30.0 22.0 28.0 16.0 32.0 40.0 47.0 37.0 31.0 17.0 34.0 25.0 32.0 NA NA NA NA 2.0 NA 1.0 NA NA NA NA NA 1.0 NA NA NA NA NA NA NA NA NA NA NA -0.863790256395248 0.007911788680711459 0.016907384030013527 GO:0009266 response to temperature stimulus biological_process 25.37834456378986 25.77387626087172 23.88508168755413 25.352206880437393 23.32622305952904 25.484088992521208 25.62346374708149 26.080218866620324 24.46202400026841 25.47934112894053 25.38152081051892 25.788084264527093 26.209905336815748 25.653142293629326 25.293765331184677 25.413676970994896 25.641704440966805 25.216133347842952 26.717405086929325 26.69847477553635 25.44821096400568 25.25783805502801 24.440933996041235 26.29575930803333 24.78284510706107 25.718287883666182 34.0 43.0 27.0 55.0 61.0 61.0 57.0 54.0 69.0 68.0 82.0 42.0 71.0 49.0 63.0 58.0 94.0 114.0 49.0 31.0 49.0 58.0 60.0 66.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.39553169708186076 0.0940685547103812 0.1379524750629327 GO:0009267 cellular response to starvation biological_process 21.701057599896746 21.88238451472717 21.06557153237473 21.392267410658814 16.526840597633566 18.32832110890906 21.865534538245488 21.791034417264193 21.382207501232518 22.51307077212306 22.88504796255428 22.94870322414945 21.985977909962926 22.348657274886303 20.743672298094868 19.904424173953558 22.108262348323056 21.380062426345688 21.866036199333358 22.464703577996517 21.895892544152137 20.125299010836248 19.97495383945006 20.874623692258048 22.292366518720783 22.875222841244355 2.0 1.0 1.0 1.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 2.0 1.0 3.0 3.0 4.0 3.0 2.0 2.0 2.0 2.0 3.0 3.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA NA NA -0.18132691483042507 0.7728299926844475 0.8146045868836069 GO:0009279 cell outer membrane cellular_component 26.663595129436285 22.713151777586194 24.173367809731694 18.80929964462437 NA 21.58468765343738 26.680723406308108 21.224775052488344 26.72420504296997 23.243560135457567 27.30475206895752 24.400156758746448 26.748075209937486 21.834044333761266 25.377380965206665 19.70521019597929 26.70938762122462 20.776133113647425 26.48048808219689 23.713808397833336 26.78052919263856 17.41929960174454 27.130782229945634 17.83948519078569 27.10440721311139 24.50620642218071 8.0 1.0 NA 4.0 15.0 6.0 19.0 8.0 20.0 8.0 23.0 5.0 22.0 4.0 16.0 4.0 33.0 14.0 17.0 1.0 20.0 2.0 18.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.9504433518500903 8.184658360899193e-05 0.0006159890947550879 GO:0009308 amine metabolic process biological_process 25.99362466418103 26.563926617677122 24.914862120276197 25.067245104215388 18.250673504698355 24.45410654227216 26.053367815157472 25.988834614079558 25.35892602909193 25.705372030495592 26.238420043368663 25.67283971801001 23.873214278285516 19.126816036389705 23.899342556213664 26.885779875424696 24.583824336610583 24.99627525821128 28.55811912727386 29.239502622085123 26.469020059651022 19.509220775954145 24.291505002699108 27.22161002476253 23.649722880719857 23.006363987005084 12.0 7.0 3.0 32.0 24.0 20.0 43.0 39.0 28.0 23.0 19.0 8.0 31.0 28.0 20.0 20.0 137.0 88.0 37.0 4.0 17.0 20.0 19.0 8.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 -0.5703019534960916 0.6441672226837103 0.7073013587238495 GO:0009311 oligosaccharide metabolic process biological_process 26.05633106283045 27.148256496748644 27.203272432900363 26.906022760223745 27.065287861257467 27.4921792429184 25.524552821863125 27.700296373475016 24.466636667874628 26.72381473872277 24.549471413500296 27.193710695346326 25.883655703770906 27.12686013713096 27.196690123483915 27.97043806881551 24.895061614808693 26.910762326393623 26.84711646738368 26.220683284843336 24.611806485117523 26.990321490948357 24.739039916001644 27.120601635048818 24.581979311858355 26.498602723415885 176.0 153.0 159.0 171.0 82.0 195.0 48.0 168.0 72.0 175.0 106.0 125.0 158.0 271.0 76.0 177.0 163.0 151.0 64.0 152.0 60.0 159.0 73.0 155.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 4.0 4.0 -1.0919254339181954 0.009374768459434895 0.01937038251220985 GO:0009317 acetyl-CoA carboxylase complex cellular_component 25.28621987842871 23.63692299708589 23.024355060738287 18.494454018617112 21.262300881549226 20.641562960260245 25.269127852793716 23.855734059667594 25.392697503621697 24.03818439125493 25.59563855523023 24.865286413448327 25.609383267261013 22.718472916469132 24.503763142066717 22.570265083619862 25.059038598463182 24.24253584200509 25.59176883075293 23.830961530293198 25.80612664029548 23.049111683401843 26.340216814692965 21.971627924403286 25.276410032127604 24.87944649089767 3.0 2.0 8.0 3.0 24.0 3.0 23.0 3.0 27.0 9.0 22.0 1.0 12.0 10.0 14.0 7.0 24.0 12.0 11.0 4.0 19.0 2.0 23.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.6492968813428206 0.0022136919545913893 0.006045268182341475 GO:0009325 nitrate reductase complex cellular_component 21.84117926637661 22.059252992576972 21.23176408491104 NA 18.67985444560061 16.866390323308888 21.275356444676206 21.495693417221762 20.87175749894596 23.46904284455576 20.288112935232128 23.211342311126906 23.18493198498153 20.44682211529289 22.172941534105668 18.97128037405427 21.343513804036487 22.38747174778252 21.35903672422972 20.87763775791877 22.055266761856732 20.210948901492323 23.375261078944263 22.21231280996224 20.61977106245915 22.974639205732387 9.0 NA 4.0 2.0 9.0 13.0 6.0 27.0 6.0 15.0 15.0 8.0 14.0 4.0 10.0 17.0 15.0 7.0 12.0 8.0 19.0 11.0 10.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.21807372620036247 0.8535135775742164 0.8883944493850059 GO:0009331 glycerol-3-phosphate dehydrogenase complex cellular_component 19.212794486884576 21.201122929482192 19.840811138475594 20.882220068900974 19.25605242853614 19.879386576252237 18.039298272299305 21.678039161740138 14.940595256095625 19.55634784824664 20.107242844429518 21.281287858441857 16.692831291959372 22.150669871505567 20.162477173754045 21.74320505713924 20.14150910927516 20.950912282277947 20.34632157672761 20.36749517061475 17.404040682530848 17.219715246342265 16.340554751390947 22.70898666732712 18.0440031957894 19.61532901484744 4.0 3.0 4.0 4.0 1.0 6.0 1.0 3.0 3.0 5.0 1.0 4.0 2.0 7.0 3.0 8.0 4.0 4.0 2.0 2.0 1.0 8.0 2.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.9883284425976164 0.004669131805023211 0.010994483948432015 GO:0009360 DNA polymerase III complex cellular_component 19.41140074752764 20.20603670100561 19.21381501275644 19.959763850641497 20.672867056750537 19.213505248271453 18.017046053949546 20.10256340652164 16.19412138809226 19.401685322834272 19.370525373920398 19.62736134934097 20.6621401764261 20.36470794167372 19.448044900762987 18.38022937137946 18.341300159887165 NA 16.316433364469017 18.60732309809444 20.749970803821586 21.29488766828904 16.35303564428987 20.97465453356789 18.728392554557896 21.148758086159337 2.0 3.0 1.0 3.0 1.0 5.0 1.0 3.0 3.0 3.0 5.0 4.0 4.0 3.0 2.0 NA 1.0 1.0 5.0 1.0 1.0 5.0 3.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7946359534779681 0.06483815699206645 0.10089528669089641 GO:0009374 biotin binding molecular_function 20.013757211966684 22.87668453490553 16.671245219876567 NA 19.203256803767225 NA 17.33855814399791 22.881832236538912 NA 24.337804120104664 NA 21.829656969442983 21.678244161561214 21.571788569827905 19.017444670973283 22.575551499632663 19.767192146747078 23.195115341652986 19.650774488703025 20.819248803296663 20.424685874774173 21.63732482156384 20.92811332235179 22.21960172585409 19.43309582508628 23.87519833461189 1.0 NA 3.0 NA 2.0 7.0 NA 18.0 NA 9.0 6.0 7.0 3.0 9.0 4.0 9.0 4.0 4.0 5.0 8.0 4.0 11.0 4.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.8629273229388446 0.00050654148469229 0.0019244720881558927 GO:0009380 excinuclease repair complex cellular_component 20.78428779650287 21.32261708169148 21.51053586751598 20.307038264410046 21.24904270714061 21.50219233074285 22.11441383142952 20.53294174996003 19.89111101147964 19.59014567197336 21.2246199733603 21.956109854427133 20.918839602381038 21.998560196106386 18.52204166583207 21.647988664041556 19.187020677671235 20.726328770240112 20.491550979575702 21.140806818844922 18.238787894898586 19.4999168238156 19.53910117218368 22.65976445284632 21.378645716865304 20.886676735036755 8.0 5.0 12.0 10.0 2.0 8.0 8.0 6.0 11.0 13.0 5.0 13.0 3.0 12.0 4.0 12.0 8.0 9.0 4.0 4.0 4.0 20.0 12.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5383292851886097 0.24821307898992373 0.31935043564889154 GO:0009394 2'-deoxyribonucleotide metabolic process biological_process 24.19152500470955 23.794205010580782 22.466921428476034 23.84731105440016 23.18038464837245 23.121737146246492 23.51540956910652 23.28217242467474 24.178888298200565 23.132532877757512 24.769848459611698 23.59854111533978 25.628071202757845 24.36324643172161 23.034346047020932 24.14462881199825 23.725599954359307 23.759846501702185 23.353147489541463 24.41707941553938 23.761711664169212 22.54079310339427 24.82139428145386 24.40542021340952 24.63815502864017 23.652810254758677 37.0 44.0 24.0 38.0 44.0 30.0 41.0 38.0 54.0 65.0 83.0 57.0 27.0 53.0 32.0 54.0 55.0 62.0 31.0 25.0 67.0 47.0 71.0 53.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.3973199941287682 0.5637028616507731 0.6360770084449954 GO:0009396 folic acid-containing compound biosynthetic process biological_process 25.305385899097573 22.28918730392077 20.421167125471907 21.256506799352533 17.382100037946756 21.61842503118652 22.400919508036903 22.086463717724826 21.663938820319068 21.584746769765914 23.616478756756788 22.46378076967158 22.337914057733137 22.999525917797204 27.082514899604544 21.85033275338644 22.804731659225016 21.089630381153704 28.155644766616515 22.60278025359715 19.010167600320344 NA 23.17166954525879 23.364631110941485 23.329896506098823 22.442736360751802 8.0 6.0 2.0 12.0 9.0 20.0 11.0 12.0 12.0 13.0 9.0 13.0 16.0 17.0 6.0 10.0 18.0 21.0 8.0 NA 13.0 23.0 15.0 14.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 3.016198595176803 0.46018093544712035 0.5412872831649446 GO:0009399 nitrogen fixation biological_process 23.654486276063434 26.27367104326195 24.061038300339128 25.140108805408612 25.586639021112795 26.42106741978799 23.085265978883914 26.05814170909659 20.860116098864705 25.80592153442854 21.774189435007926 25.69484588012064 22.89519711263997 26.059218945529352 23.4583486307055 27.049845070636223 21.92247618769888 26.66935672046837 24.076342832575673 25.11069605938417 24.421803597820396 26.422628964681447 22.615510373506805 27.279448307104115 22.581570468308914 25.818459545352912 16.0 22.0 20.0 28.0 12.0 24.0 7.0 26.0 9.0 24.0 14.0 14.0 15.0 35.0 8.0 34.0 18.0 19.0 24.0 34.0 16.0 38.0 13.0 30.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.619184767198515 5.312128159411724e-05 0.0005099643033035255 GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system biological_process 25.52682481614244 26.644070336274577 25.965698861009077 25.953724936550497 25.672577039132968 26.862099024768497 24.52205117420188 26.80706989460685 24.23018413559554 26.316800245071693 25.226549677832523 26.62843959101628 25.751105844677948 26.54077613382237 26.451606188655912 27.469326597277952 24.85497194915723 26.94628634650559 26.718355052645467 26.489515297299995 25.07954503505957 26.28953073084319 24.26788230966864 26.465537297329075 24.99381873564449 26.342467076952644 32.0 33.0 43.0 40.0 29.0 49.0 27.0 45.0 33.0 32.0 35.0 20.0 44.0 37.0 25.0 51.0 60.0 50.0 33.0 32.0 33.0 40.0 37.0 45.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.117245520132137 0.0006583371695572323 0.0022696264851033866 GO:0009404 toxin metabolic process biological_process 21.7744854482504 25.41870114246915 22.344066307948008 25.38393601052255 22.80966359939525 23.18204807448703 21.30079997837321 26.67524989366701 18.995740830041715 25.65392057517888 16.732722548359877 23.574034408068968 NA 25.765045606309954 22.8761800522718 24.815464798784838 22.073888727964487 25.388329700618574 22.605680161259894 25.570972159728175 21.122285122322584 25.363170608116523 19.077416230080107 25.855995986819053 21.094026619272185 24.753248645684828 10.0 18.0 8.0 14.0 6.0 16.0 2.0 16.0 2.0 16.0 NA 12.0 12.0 12.0 10.0 20.0 14.0 16.0 10.0 12.0 2.0 14.0 6.0 12.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 NA 2.0 3.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 -3.644215694218751 4.865007418510381e-05 0.0005099643033035255 GO:0009405 pathogenesis biological_process 22.487709950224247 21.751170894028977 20.49879413029381 20.286185339710816 22.78450130746745 22.21058297861893 22.662106561719927 23.21958897371477 21.451711410287505 21.320232503816925 21.180513783903006 21.75204267875059 23.37923241776053 22.44821705738157 23.036239581145505 19.00420800829294 19.004673152501866 21.277008357438728 19.23311116796312 21.696303434417835 22.093334842434093 17.654287648338226 23.67113222060113 22.53009442349473 23.455233050301448 20.82487684902824 3.0 10.0 4.0 6.0 5.0 23.0 3.0 12.0 4.0 9.0 10.0 20.0 3.0 6.0 2.0 3.0 2.0 5.0 3.0 1.0 7.0 17.0 6.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.7365390561952694 0.2040238704744366 0.2705863871967023 GO:0009408 response to heat biological_process 25.32270159550509 25.60102216382649 23.602042671866048 25.177168157083287 23.273120138610143 25.11892717439003 25.589083851215612 25.87796983572477 24.46202400026841 25.399825419611435 25.359831847264136 25.619775844388624 26.191454326432623 25.28451430001313 25.24283646669641 25.263349866760567 25.50867610383057 25.08951133928956 26.678586734687162 26.629234650143854 25.43368153110437 25.217484477623128 24.390880439807486 26.036388584779356 24.590464372211642 25.5864781586143 25.0 29.0 23.0 28.0 59.0 46.0 57.0 47.0 65.0 57.0 78.0 27.0 62.0 34.0 61.0 45.0 85.0 100.0 47.0 24.0 47.0 42.0 56.0 56.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.27832056832139784 0.3263484733220724 0.4012639356708831 GO:0009423 chorismate biosynthetic process biological_process 21.90292820672523 24.05720800287959 22.376976468009094 24.079589783683605 20.267516616872907 22.34934145029233 20.473581280824614 24.283528168241357 18.80769183907968 23.789366379467644 21.82926044902488 24.29488747798304 22.42326667297465 24.58104736005153 22.38798261974484 24.27626200002536 23.01090528753313 24.6329180253533 22.552746856517228 23.61592664420972 21.439210476484327 22.67168237255336 21.398360399647867 24.740221869301948 21.689134297103454 23.50478076829981 15.0 43.0 7.0 17.0 8.0 49.0 7.0 41.0 15.0 51.0 25.0 52.0 21.0 49.0 11.0 64.0 24.0 45.0 9.0 25.0 15.0 54.0 18.0 36.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.154279796154359 0.0001386794054294884 0.0007006959432226783 GO:0009432 SOS response biological_process 24.266750383092926 24.94521644894289 24.74567970916133 25.02914941529455 24.81014493874056 25.407032275155697 24.024466050614762 24.605991868020954 23.60565312384998 24.48159058013524 24.03043044177412 25.324041951379822 24.48602855995658 24.818805859007448 23.74995967042685 24.62455319610331 23.197137409472 24.72978344698105 24.61737189085978 25.17810480943677 24.883390678964386 24.513796911476692 23.85712969871417 24.978662866334528 24.148694629152885 25.24228270121331 36.0 32.0 38.0 48.0 21.0 39.0 33.0 35.0 44.0 55.0 51.0 50.0 24.0 54.0 18.0 45.0 38.0 47.0 35.0 28.0 32.0 59.0 50.0 45.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6784660658499639 0.00268017172806849 0.006910856026093958 GO:0009435 NAD biosynthetic process biological_process 23.066987642620372 23.217597331434607 22.454973243425307 23.138836131246705 23.654918882187015 23.03414726473195 23.152278910821234 23.52438153210909 22.706768726223284 23.064779886689703 23.6720306827174 23.38143513720417 23.63385905760963 24.12982050466661 22.994619622288862 22.635109397260088 22.505571121362056 22.516002539017943 22.50149948061555 23.230151984592126 22.304161226953145 22.39510731282236 22.092734030690107 23.6251750659604 23.74286219578873 22.984020275692426 8.0 13.0 13.0 8.0 16.0 18.0 12.0 17.0 14.0 11.0 19.0 16.0 14.0 12.0 9.0 13.0 19.0 19.0 12.0 13.0 14.0 16.0 19.0 10.0 NA NA NA 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA -0.1506096888142352 0.5253727863737021 0.6008633207515945 GO:0009451 RNA modification biological_process 23.895303020886878 25.64970220418315 25.34059012113148 25.271650326118845 24.223882244522127 25.84857455492604 22.65710418180069 25.80529373873128 22.32901408806455 25.043420464482946 23.934159796231107 25.42505465476441 23.925724073508764 25.457611028757377 24.579611628654266 26.183397901387906 22.67503985346246 25.54488079309355 23.917792687500103 25.793507444573105 23.963358644157964 25.328690726420426 22.519244924289907 26.374136272829308 23.432245063417465 25.01861217509368 48.0 101.0 50.0 121.0 36.0 124.0 25.0 93.0 68.0 110.0 62.0 86.0 45.0 152.0 28.0 130.0 73.0 93.0 41.0 94.0 26.0 150.0 49.0 84.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 -1.7543991832962718 8.637667594722788e-05 0.0006159890947550879 GO:0009507 chloroplast cellular_component 24.536428651071223 24.536270579482945 23.73195882606764 17.43993595537273 22.59315647781711 23.20010920829669 23.40892836718213 24.771965001923967 24.73289691602537 25.846068372892052 25.93157226327125 24.586983560766097 24.759251481613077 22.74726684454424 24.571538198993537 23.318558220889173 23.93462170844829 24.850706274729784 23.756402088248404 24.163267993901663 25.005081529368173 24.25691983449649 25.04765180960466 23.013158299841514 24.004538453699364 26.119967835594693 12.0 1.0 9.0 3.0 13.0 11.0 16.0 12.0 15.0 12.0 14.0 9.0 17.0 6.0 13.0 11.0 12.0 14.0 16.0 11.0 14.0 6.0 14.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.00015807158827740864 0.6441672226837103 0.7073013587238495 GO:0009605 response to external stimulus biological_process 25.84254662630709 26.277571880372424 25.96139148767497 26.28155290656076 25.819376840706678 26.428221106428985 25.674567224988145 25.966875955424342 25.86094760929416 26.077122985611982 26.07454640244801 26.830135647933375 26.06027246249052 26.32622983002077 25.91441150784877 25.742829558082576 25.17014919833265 25.99882440238689 26.05392591380744 26.590017979943514 26.21380650024741 25.645373978835092 25.07726416501184 26.207273782137023 25.801024015128842 26.716513653222474 86.0 72.0 80.0 100.0 64.0 94.0 136.0 82.0 105.0 131.0 137.0 116.0 64.0 124.0 50.0 108.0 89.0 107.0 82.0 64.0 78.0 140.0 116.0 104.0 3.0 3.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 2.0 2.0 3.0 2.0 2.0 -0.43502525406533366 0.013042519940568903 0.025877686622941164 GO:0009607 response to biotic stimulus biological_process 21.72323670778597 20.64025575258545 17.5973256134569 20.990058156891124 NA NA 20.2985105503726 16.18034841495772 23.840516628055482 NA 16.288235946851096 20.92493427020617 22.400875231560192 21.781575594649773 20.768345707611736 18.91530920884669 NA 18.90519727516316 NA 19.35997531919379 18.296092461171643 NA NA 21.804775758868352 NA NA 4.0 4.0 NA NA 6.0 1.0 57.0 NA 2.0 6.0 20.0 9.0 10.0 4.0 NA 2.0 NA 4.0 4.0 NA NA 10.0 NA NA 1.0 1.0 NA NA 1.0 NA 1.0 NA 1.0 1.0 1.0 1.0 1.0 1.0 NA 1.0 NA 1.0 1.0 NA NA 1.0 NA NA 1.0829809552005187 0.907868500949536 0.9266349541778063 GO:0009725 response to hormone biological_process 18.696578774088376 21.95376802813304 17.041541616741096 21.215515926602414 14.802535732482758 21.4531044018516 16.19463320873981 21.85520971241421 19.39669951353797 21.843828761187762 20.7637050754652 22.70712252864921 14.889243061109436 20.724190290592045 NA 21.445661817994075 18.0178046006368 23.32709062988541 18.161380949769033 22.189294848181486 NA 19.599950495276754 19.61272291913899 22.935393263326787 17.183086880705268 18.301723201613555 2.0 6.0 2.0 2.0 2.0 6.0 4.0 2.0 4.0 8.0 2.0 8.0 NA 4.0 4.0 8.0 4.0 6.0 NA 2.0 4.0 12.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 -3.2571892540446648 0.00036993149163163074 0.0014703009603703032 GO:0009889 regulation of biosynthetic process biological_process 29.57351733925539 30.40632002178809 29.74614615150953 30.033017565271074 29.910333127383822 30.19210406051248 29.132603001464194 30.66840958125468 29.281454802448877 30.66401171983529 29.525047088546014 30.526303543009284 29.61396203178249 30.219527816660825 29.42845228002919 30.313550340364948 28.890594972793913 30.333300366192397 30.09066417951221 30.875926961293498 29.832274592101808 30.09165838450923 29.357088050165164 30.211933834078806 29.637885521814464 30.48333172777888 671.0 792.0 663.0 746.0 686.0 1055.0 681.0 1079.0 873.0 944.0 919.0 882.0 668.0 926.0 572.0 980.0 1211.0 1186.0 828.0 751.0 648.0 978.0 904.0 1139.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 -0.8328026825327015 4.146041132679973e-05 0.0005099643033035255 GO:0009890 negative regulation of biosynthetic process biological_process 24.386705583292827 24.207729278941088 23.30030518237217 24.007691038230053 25.246162682527967 23.464966997040506 24.42263975013986 23.40337551528133 22.83512001622161 25.20906481771488 24.745606760480232 23.6375480396986 24.89861773367821 23.950070591193576 23.433366644229807 22.233594686557442 23.04827292649719 23.078096615980353 24.1721939722462 25.721564622589497 25.389531502842146 23.632627258704492 23.941434045243287 23.46345801412777 24.56031329159957 24.89656886761437 40.0 50.0 56.0 28.0 50.0 52.0 40.0 68.0 54.0 40.0 74.0 40.0 28.0 32.0 22.0 44.0 58.0 88.0 67.0 50.0 36.0 42.0 64.0 82.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 0.17897630435173895 0.5637028616507731 0.6360770084449954 GO:0009891 positive regulation of biosynthetic process biological_process 22.972007638553986 23.86511762035008 23.370152744534078 23.21856497907633 21.81136861212874 23.93164219205457 22.13719494790987 23.93762041672264 23.802478396133004 23.75146906942937 23.78163914358533 23.97672304740037 22.99087022295184 23.600506099407877 22.219753686746568 23.835016859025608 22.71154286980865 24.31154870303079 22.531778361699 23.871667803031336 22.18471872405338 22.94699261485209 22.982741124474806 24.60706858979938 23.434181893395106 23.67603686671784 22.0 28.0 14.0 28.0 20.0 46.0 32.0 42.0 32.0 36.0 22.0 30.0 18.0 52.0 24.0 50.0 24.0 36.0 18.0 24.0 28.0 50.0 32.0 40.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 -0.8931099817960941 0.0012242832644312096 0.0037265988146589013 GO:0009892 negative regulation of metabolic process biological_process 26.590312586415 26.027455838899183 25.196143627770912 25.74472652631281 26.951894722151376 25.578745647619066 26.58079173016357 25.19123479914835 26.028517018902324 26.86179658786861 27.07381363360092 25.55507134489965 27.190102547062 25.876145158202696 26.03239856250001 24.612283375577363 25.499505520351008 25.149014177735253 26.781066491445365 27.44453387945041 27.178873692244693 25.41981408876989 26.36585739285643 25.601360838188327 26.728322503204524 26.6037456932264 137.0 161.0 183.0 110.0 203.0 169.0 219.0 221.0 242.0 153.0 296.0 139.0 148.0 117.0 112.0 162.0 277.0 299.0 225.0 165.0 198.0 155.0 268.0 266.0 5.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 4.0 5.0 5.0 4.0 4.0 4.0 4.0 6.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 0.5628567475158164 0.043308142810791976 0.0706517153305469 GO:0009893 positive regulation of metabolic process biological_process 25.40182616277227 26.114597420445985 25.679743542824397 25.43605899403148 24.12993210898578 26.173744888496532 24.45206851679786 26.16955556080601 26.323721678006144 26.036315868997136 26.127138182920273 26.35445985638396 25.32805564032569 25.88654044740769 25.67330515916152 26.078409335597204 24.992057505576767 26.4193891160738 24.843686314190265 26.082391790918606 24.50664681894073 25.22574715773066 25.26218793797349 26.853209407008315 25.75041640894987 25.987492676509294 105.0 134.0 67.0 137.0 97.0 224.0 169.0 213.0 163.0 186.0 113.0 144.0 108.0 257.0 115.0 244.0 117.0 177.0 90.0 117.0 134.0 244.0 157.0 197.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 4.0 7.0 7.0 7.0 7.0 7.0 4.0 7.0 7.0 7.0 7.0 7.0 -0.7127712576737153 0.005583616806378765 0.012692811975156102 GO:0009898 cytoplasmic side of plasma membrane cellular_component 23.64908867002832 24.965107846451048 24.30392691626216 24.75167801150581 23.814170902996 24.22896952521523 22.299932325893327 24.824659022141073 21.544201031385192 24.927612554423558 23.045900462816352 24.89345115929883 23.91533409549778 24.752131211351237 25.0710259104892 25.449122823495802 22.856497947991038 24.669242546478486 23.683009837898783 25.38716417052773 23.81307271542036 24.72954023978097 23.037490992849907 25.44898374688693 23.258790550378148 25.02223629444993 17.0 19.0 21.0 24.0 18.0 24.0 14.0 23.0 22.0 26.0 22.0 17.0 30.0 30.0 18.0 24.0 31.0 21.0 26.0 27.0 23.0 27.0 23.0 35.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.3160191764227278 0.00034415785384659113 0.0013990521224773477 GO:0009986 cell surface cellular_component 29.0910578072221 30.030180985781122 29.46620840332023 29.36118136212832 30.007724318095136 30.01882857650589 28.73474811545083 29.991484740060464 28.287870983428984 30.259578292719212 29.19242807551139 30.132628521727142 28.85355253493957 29.50890988575185 29.528922731155426 30.04577608187107 28.719499154956843 30.38034179209627 28.837490717958932 30.216994437903015 29.30303609941243 30.21330595130613 28.094641096072955 29.734634468978662 28.961557678629287 30.15284449604545 74.0 50.0 68.0 88.0 80.0 78.0 110.0 85.0 100.0 80.0 76.0 46.0 107.0 60.0 82.0 81.0 98.0 96.0 89.0 75.0 90.0 63.0 83.0 94.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9391231785590222 0.0001748865925420931 0.0008236168584623857 GO:0009987 cellular process biological_process 37.97914812840825 38.66165680847296 38.05602124008922 38.02772004108989 37.70888235668765 38.58996024191936 37.608464667239545 38.826304781064096 37.60113821598528 38.57617521486405 38.14377409463906 38.582932485453576 38.10402372571368 38.227375794618226 38.381154619758576 39.01846240221489 37.52872733845078 39.07343284650249 38.555329991752686 38.85277169574875 37.91489575633451 38.525456112348365 37.81337341470872 38.762833062935 37.93511202272806 38.539214670355356 128258.0 127025.0 124896.0 156134.0 143298.0 202458.0 162019.0 187693.0 167624.0 190187.0 179981.0 145727.0 181010.0 191252.0 141421.0 195259.0 223170.0 212452.0 163514.0 160367.0 170865.0 178062.0 172514.0 191837.0 24.0 19.0 22.0 24.0 23.0 22.0 22.0 22.0 25.0 22.0 25.0 20.0 22.0 22.0 22.0 23.0 22.0 24.0 21.0 18.0 21.0 24.0 25.0 23.0 -0.6825086800647142 0.0002755038114342687 0.0011655212090507369 GO:0009991 response to extracellular stimulus biological_process 24.868343981066193 25.38845851233831 25.05108645078265 25.34084201196891 24.82397073244892 25.43869995332923 24.787651942840306 25.118288485879678 24.321448127169905 25.30252121037137 25.284545025301327 25.986397219598413 25.119337310603022 25.443063707025257 24.20767926679858 24.78007006471841 24.479910481908746 25.101928676146546 25.14898040400939 25.72151206176633 25.346242655414954 24.706919983060736 24.16690089794056 25.21065377931325 25.034124044321004 25.90496014370203 43.0 35.0 41.0 51.0 32.0 51.0 42.0 44.0 54.0 65.0 62.0 56.0 27.0 63.0 28.0 57.0 47.0 53.0 41.0 34.0 42.0 68.0 61.0 55.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.5201145312721174 0.011074437676156606 0.022291771322328135 GO:0010033 response to organic substance biological_process 21.010812124520324 24.283501149858516 19.36346971162846 23.537444021489787 17.124463827370118 23.775032496738962 18.51656130362717 24.177137807301573 21.794627901215392 24.16575685607512 23.08563317035256 25.029050623536573 17.211171155996798 23.046118385479414 18.063986642219746 23.76758991288144 20.339732695524162 25.64901872477277 21.518970349309527 24.511222943068837 NA 21.921878590164127 21.93465101402635 25.30411322761968 19.50501497559264 20.62365129650092 10.0 30.0 10.0 10.0 10.0 30.0 21.0 10.0 20.0 40.0 10.0 40.0 1.0 20.0 20.0 40.0 24.0 30.0 NA 10.0 20.0 67.0 10.0 10.0 5.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 5.0 5.0 NA 5.0 5.0 5.0 6.0 5.0 NA 5.0 5.0 7.0 5.0 5.0 -3.2726890253381917 0.0002821075654977551 0.0011894264923689134 GO:0010138 pyrimidine ribonucleotide salvage biological_process 25.18823708981505 25.444000735924806 25.04098584272358 24.46098380544825 24.43615296480577 24.994903655266967 24.71818924523448 25.33997471675499 24.59332182428601 25.688207965281435 25.599540836124266 25.90348845750812 25.26827137838205 25.3504844634196 23.95735669496786 25.17344277121941 24.77263026549388 25.156030762270518 25.968977143091326 25.426278900722853 26.31411458621653 25.34465807153881 24.773945846215486 26.172106282965288 25.04554524162064 25.592804514065328 29.0 21.0 19.0 26.0 31.0 23.0 32.0 28.0 32.0 41.0 36.0 18.0 29.0 25.0 33.0 34.0 44.0 40.0 35.0 22.0 41.0 40.0 39.0 35.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.2557636461097559 0.10596880912720232 0.15148805703407617 GO:0010181 FMN binding molecular_function 24.19600165204021 24.82272518985116 23.107816863686022 23.908666060484627 21.55014570557264 23.306974105650053 23.213009844247605 24.815743948365693 24.827823778678518 22.880640585423798 24.69661265280569 22.99127660527072 24.54619278168389 26.42680380685061 24.30002479939937 23.261113135765786 22.55659819305097 22.72214291584918 25.955194357320014 23.4877703553159 23.239317185213018 25.18584153671081 23.717471376151057 26.644271843621656 23.485449598471146 24.41544558810338 17.0 13.0 8.0 19.0 27.0 33.0 31.0 17.0 35.0 26.0 34.0 18.0 30.0 21.0 16.0 20.0 35.0 28.0 23.0 27.0 23.0 20.0 27.0 27.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6267235378109497 0.5637028616507731 0.6360770084449954 GO:0010468 regulation of gene expression biological_process 28.22547102715444 28.837138985031306 28.32304869471091 28.442898624930862 28.348825363666805 28.79089239732449 27.851269823963896 29.10811732601563 28.00176903139965 28.97186323470871 28.202584455294236 28.963766143932663 28.27723772079633 28.695383601651077 28.23354104899573 28.771673069112417 27.652113546779194 28.746455497094875 28.765487679281488 29.234612017873374 28.34670431807631 28.57679712691875 28.120219704682075 28.6656343430385 28.286363264287523 28.884363756238237 188.0 198.0 169.0 234.0 208.0 279.0 239.0 277.0 271.0 283.0 262.0 232.0 234.0 274.0 183.0 284.0 386.0 319.0 229.0 199.0 223.0 274.0 259.0 293.0 4.0 4.0 4.0 5.0 4.0 4.0 5.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 4.0 5.0 4.0 5.0 4.0 5.0 4.0 4.0 4.0 4.0 -0.6116679578768647 0.00010962068302139599 0.000648372570666835 GO:0010556 regulation of macromolecule biosynthetic process biological_process 28.515474361568106 29.358661232728053 28.711046365659985 28.98687706623139 28.846641850998267 29.146723767846986 28.060732865965896 29.63529977549811 28.227133679555124 29.606857048347663 28.436483384218768 29.482997772390213 28.54247945745551 29.1814426693096 28.395711493331746 29.281314223940946 27.83775009425818 29.264301838585467 29.057495164605136 29.812660060495023 28.75651700571325 29.06123853043067 28.298852375151228 29.14985587640419 28.570347377913706 29.43865983337915 301.0 350.0 293.0 341.0 304.0 471.0 301.0 481.0 390.0 427.0 408.0 399.0 311.0 417.0 259.0 436.0 559.0 527.0 371.0 335.0 285.0 436.0 400.0 505.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.8431868711599471 4.146041132679973e-05 0.0005099643033035255 GO:0010558 negative regulation of macromolecule biosynthetic process biological_process 23.38427766031669 23.207729278941088 22.30030518237217 23.007691038230053 24.246162682527967 22.464966997040506 23.42263975013986 22.403375515281333 21.83512001622161 24.20906481771488 23.745606760480214 22.6375480396986 23.89861773367821 22.950070591193576 22.433366644229814 21.233594686557442 22.048272926497187 22.078096615980353 23.151818364722644 24.721564622589497 24.383694368145203 22.632627258704492 22.941434045243287 22.463458014127763 23.56031329159957 23.89656886761437 20.0 25.0 28.0 14.0 25.0 26.0 20.0 34.0 27.0 20.0 37.0 20.0 14.0 16.0 11.0 22.0 28.0 44.0 33.0 25.0 18.0 21.0 32.0 41.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.17654838137560347 0.5637028616507731 0.6360770084449954 GO:0010604 positive regulation of macromolecule metabolic process biological_process 23.682184481439915 24.133029704520307 23.93705229579515 23.421263187404836 22.38508513571301 24.23130974711874 22.69850696127786 24.197810752530888 24.62328475468142 24.003860170225725 24.326760486418692 24.33945560695153 23.589310638947463 24.06217765446895 24.221061948423166 24.13963544516577 23.26343785688235 24.00835401407927 23.08306614022634 24.04680933235549 22.769681224774533 23.38271567324063 23.420946253970605 24.922195435141937 24.00007775754641 24.225792014202966 30.0 36.0 18.0 39.0 27.0 63.0 50.0 62.0 47.0 52.0 32.0 39.0 35.0 75.0 33.0 69.0 33.0 51.0 27.0 33.0 36.0 69.0 45.0 57.0 4.0 3.0 3.0 3.0 3.0 3.0 5.0 5.0 5.0 5.0 5.0 3.0 5.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.45084522308039254 0.03766692222862868 0.06276144050911694 GO:0010605 negative regulation of macromolecule metabolic process biological_process 25.596862035157127 24.779611716194633 24.032296288030267 24.376796032330066 25.540894635927824 24.684203343709783 25.532322949125614 23.932096724694308 25.47982170202848 25.376091300330266 26.103089678803787 24.377171748369907 26.185916314117843 24.640148058589247 25.280394675249198 23.911954312505504 24.539863386932346 24.20302074473792 25.928504401577893 26.09732871282175 25.920824358255054 24.118356341932 25.571323316766357 24.65152087963583 25.761293192321 25.176592192603827 54.0 58.0 65.0 54.0 92.0 63.0 107.0 80.0 109.0 69.0 122.0 50.0 76.0 53.0 53.0 72.0 134.0 119.0 91.0 62.0 100.0 66.0 116.0 98.0 3.0 4.0 4.0 3.0 5.0 4.0 5.0 4.0 5.0 5.0 5.0 4.0 4.0 3.0 5.0 4.0 5.0 5.0 4.0 4.0 5.0 4.0 4.0 4.0 0.8172503189624933 0.006656727227605034 0.01478219854101616 GO:0010629 negative regulation of gene expression biological_process 24.947975206979127 23.752538048189074 23.16571697903644 23.104116883405503 24.15927499518717 24.123278539118672 24.828647303153186 22.86273181135041 25.18416735114982 23.78125793163557 25.50971618577449 23.474137544231443 25.56988395598701 23.71166877417837 24.82126682394998 23.52675222295729 23.95011852584039 23.58457883858809 25.474276410128244 24.84778217305305 24.855367683159947 22.99276341432189 25.10218391737833 24.04701315174341 25.0977806803337 23.772437920417858 24.0 20.0 22.0 33.0 51.0 23.0 63.0 28.0 60.0 38.0 59.0 19.0 47.0 29.0 31.0 38.0 85.0 51.0 41.0 24.0 61.0 33.0 56.0 36.0 2.0 3.0 3.0 4.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 4.0 3.0 4.0 2.0 5.0 3.0 3.0 2.0 2.0 1.1954371587900532 0.0009986863791802587 0.0031633517797384847 GO:0014070 response to organic cyclic compound biological_process 18.696578774088376 21.964905183459514 17.041541616741096 21.215515926602414 14.802535732482758 21.4531044018516 16.19463320873981 21.85520971241421 19.39669951353797 21.843828761187762 20.7637050754652 22.70712252864921 14.889243061109436 20.724190290592045 NA 21.445661817994075 18.0178046006368 23.32709062988541 18.161380949769033 22.189294848181486 NA 19.599950495276754 19.61272291913899 23.001783351580805 17.183086880705268 18.301723201613555 2.0 6.0 2.0 2.0 2.0 6.0 4.0 2.0 4.0 8.0 2.0 8.0 NA 4.0 4.0 8.0 4.0 6.0 NA 2.0 4.0 14.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 4.0 2.0 2.0 -3.268326409371138 0.00036993149163163074 0.0014703009603703032 GO:0015031 protein transport biological_process 27.010641495900067 27.558799039371053 27.22995856523664 27.916155270735754 27.31407460742577 26.436484205868613 26.548713771657237 27.140189218576282 26.789737331058017 27.26055543597307 27.094300626318464 27.62940956460687 27.38537315728443 27.899467795529784 26.819614803907772 27.457458093597626 26.365114137123342 26.807102067506914 26.85923113564995 28.16241104760429 26.77012347929817 27.3878514189134 27.14211987367807 27.66904805048469 27.39350599960473 28.011305586594318 181.0 169.0 166.0 155.0 166.0 146.0 162.0 220.0 205.0 220.0 225.0 181.0 188.0 180.0 150.0 193.0 216.0 237.0 176.0 184.0 190.0 199.0 229.0 301.0 4.0 3.0 3.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 -0.5481575434709853 0.011074437676156606 0.022291771322328135 GO:0015035 protein disulfide oxidoreductase activity molecular_function 24.616762200941906 25.09579473337368 23.443262456105682 24.67064173973084 22.353445121760863 23.950492066101926 25.840381842140108 26.16807050838115 23.68432879883287 25.226540045414986 25.666071448315247 24.337799003565184 25.25206894615839 25.438135554455265 23.72948795280353 24.98401552515032 23.147892547474807 24.86583855047611 23.10065659266514 25.355902053255683 24.74827455702709 24.833506231982003 24.365193155741824 24.992078751233358 25.364631927572823 25.10490897690592 15.0 14.0 9.0 16.0 20.0 25.0 20.0 27.0 18.0 24.0 17.0 13.0 22.0 18.0 17.0 19.0 14.0 20.0 14.0 13.0 13.0 14.0 21.0 26.0 NA NA NA NA 1.0 NA NA NA 1.0 NA 1.0 NA NA NA NA NA NA NA NA NA 1.0 NA NA NA -0.47903253243177346 0.13332693177434943 0.18549833985996442 GO:0015036 disulfide oxidoreductase activity molecular_function 24.84538062782228 25.15742809710553 23.473506355545467 24.750976372162427 22.353445121760863 23.969470234137468 25.927244210630388 26.28071032510583 24.084224475175386 25.270206700910958 25.92966804887973 24.46703126799537 25.40501083546939 25.44916699352612 24.60640674325121 25.04129359204804 23.3542529306152 24.925857676876163 23.704475073765078 25.466846375788695 24.80652860805272 24.836364621774788 24.622869867110573 25.04016004268429 25.56589849050157 25.109149176950922 16.0 15.0 9.0 17.0 27.0 32.0 29.0 28.0 24.0 32.0 23.0 14.0 27.0 21.0 20.0 22.0 21.0 24.0 16.0 14.0 18.0 17.0 32.0 27.0 2.0 2.0 1.0 2.0 4.0 5.0 3.0 2.0 3.0 4.0 4.0 2.0 3.0 3.0 3.0 3.0 3.0 4.0 2.0 2.0 3.0 4.0 4.0 2.0 -0.3120474692832502 0.2040238704744366 0.2705863871967023 GO:0015075 ion transmembrane transporter activity molecular_function 29.61323384746439 30.636745664841953 29.38779801510924 30.05234606599647 29.074685521233487 30.38840799362396 29.243553277799602 30.58610439131902 29.454988112275373 30.528052631295186 29.726498293405594 30.68509017800293 29.77507364940433 30.43206210348716 29.361121519300927 31.04756764130373 29.449286496805964 30.801963465136343 30.10035115311376 30.689438184813792 30.06364086845749 30.431678464399962 29.650091602120074 30.939266992873673 29.69669443758591 30.78430281530188 601.0 723.0 545.0 827.0 554.0 945.0 761.0 962.0 697.0 990.0 778.0 824.0 769.0 1048.0 586.0 875.0 712.0 1032.0 697.0 910.0 697.0 909.0 741.0 1113.0 5.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 6.0 -1.023511817377564 5.312128159411724e-05 0.0005099643033035255 GO:0015077 monovalent inorganic cation transmembrane transporter activity molecular_function 27.464566080764843 28.52532466169985 27.313307640412432 27.931891748370308 27.066920971396275 28.34546813081629 27.07241514202112 28.47620006706116 27.16180266978704 28.42521729640385 27.573311012129327 28.564094607811985 27.52778833382578 28.24541930891108 27.203996727168413 28.949024317458505 27.204808529367927 28.70866440757059 28.044895534552804 28.60296662733249 27.97917556997813 28.384318205151054 27.468646646792774 28.764463487115368 27.532266213059586 28.642671280542288 124.0 137.0 122.0 167.0 107.0 177.0 136.0 170.0 128.0 185.0 134.0 138.0 143.0 190.0 100.0 155.0 146.0 192.0 147.0 181.0 122.0 145.0 132.0 207.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 -1.0607585809350084 5.312128159411724e-05 0.0005099643033035255 GO:0015078 proton transmembrane transporter activity molecular_function 27.458094191873563 28.509301675515232 27.309116454341307 27.899361526044466 27.06291672684135 28.327473229384303 27.0709348053853 28.460212172267127 27.150907931708197 28.414857622800326 27.567913209796995 28.542247191288137 27.518913523780107 28.234260658201237 27.169562614840483 28.926531655948235 27.201990060915822 28.702913494944696 28.03944502485447 28.581409823494234 27.977335807083012 28.36828911089795 27.468646646792774 28.756368163702515 27.52826422431891 28.62909106279353 120.0 121.0 118.0 151.0 105.0 160.0 132.0 161.0 125.0 163.0 132.0 128.0 141.0 168.0 97.0 144.0 142.0 177.0 145.0 165.0 122.0 134.0 128.0 195.0 4.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 5.0 4.0 5.0 3.0 3.0 4.0 3.0 3.0 3.0 2.0 3.0 4.0 3.0 4.0 4.0 -1.0512074836416687 5.312128159411724e-05 0.0005099643033035255 GO:0015101 organic cation transmembrane transporter activity molecular_function 22.813260980331183 21.563575339745256 21.77226916310007 21.20241230460964 21.973540536199845 22.398109061738683 22.003061385593373 21.24974847367595 23.802051151399976 21.04018907226588 22.574263493082427 21.95879459368361 23.23040094920108 21.800887555327908 22.389335344559736 21.278871259989504 23.359563219054323 19.889390551612788 21.56155251571012 21.576244976978675 23.124054135374546 21.703749945255915 22.951546191578327 22.093898561176925 23.13651848438777 21.157433706457226 8.0 6.0 9.0 10.0 8.0 8.0 25.0 8.0 16.0 12.0 18.0 12.0 16.0 3.0 15.0 2.0 10.0 12.0 10.0 8.0 22.0 8.0 16.0 6.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.249685640585927 0.0009986863791802587 0.0031633517797384847 GO:0015103 inorganic anion transmembrane transporter activity molecular_function 20.964236872753013 23.287144534334946 21.879033921606336 23.11100072450551 22.20955562658629 23.92760386824153 NA 23.57721306739263 18.126581888869428 22.158119762444677 NA 22.352799939027985 19.78894948208356 23.553238548547114 20.624391102169106 23.130810449268512 19.440005305929784 22.67319883145405 21.97211542400382 23.79922684880861 19.634858300005547 22.96434993494741 NA 24.11649447355072 20.262006572962875 22.543279716266607 17.0 29.0 14.0 32.0 NA 28.0 3.0 14.0 NA 26.0 8.0 48.0 6.0 34.0 6.0 26.0 22.0 30.0 7.0 14.0 NA 30.0 8.0 16.0 2.0 4.0 2.0 3.0 NA 3.0 2.0 3.0 NA 3.0 3.0 3.0 3.0 3.0 2.0 3.0 4.0 5.0 3.0 3.0 NA 3.0 5.0 5.0 -2.322907661581933 0.00016552160560065154 0.0008236168584623857 GO:0015144 carbohydrate transmembrane transporter activity molecular_function 27.00036160707921 27.10289430872355 27.29762469318521 26.770543046976535 27.147196168260606 26.644700031808988 26.685551970028076 27.593763769374608 26.81755696030863 27.384246632026585 27.22177009068634 27.291307165445318 26.781841619921146 26.60580036938953 27.50289284698541 27.26141986419996 26.157600114874768 27.198719513500265 27.561150671068226 27.050743348987698 27.165706759941568 26.478074435151967 26.343171707706446 27.09422634512639 26.58319325076416 27.3866560889372 90.0 70.0 104.0 89.0 113.0 113.0 115.0 111.0 132.0 107.0 124.0 66.0 132.0 149.0 99.0 98.0 177.0 113.0 121.0 91.0 118.0 123.0 123.0 128.0 7.0 6.0 6.0 6.0 4.0 6.0 3.0 5.0 4.0 6.0 7.0 5.0 6.0 6.0 6.0 6.0 8.0 5.0 5.0 5.0 5.0 5.0 5.0 6.0 -0.10253270164433914 0.5637028616507731 0.6360770084449954 GO:0015145 monosaccharide transmembrane transporter activity molecular_function 24.849566999911083 23.50389690903381 22.67052958043399 22.154807166654493 23.085350484437427 21.890019384153668 25.17772272878061 23.27455686563177 25.274902927975997 23.41757218691585 25.639840061545893 23.799458216707073 25.243109917772195 22.75611881973348 24.835188392652164 24.26818802922077 24.511000177427587 22.695584885199352 25.44215678264002 24.10295875007576 24.349715689710933 22.364154970091352 24.883829928339015 24.221218020213556 24.569244108946915 24.336285923096256 13.0 8.0 17.0 11.0 53.0 19.0 57.0 20.0 62.0 25.0 50.0 11.0 43.0 28.0 41.0 15.0 68.0 32.0 34.0 16.0 58.0 25.0 49.0 28.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 1.3456700908772739 0.0012242832644312096 0.0037265988146589013 GO:0015149 hexose transmembrane transporter activity molecular_function 23.72346148162823 22.895118114366536 21.622073872771736 21.21722584420272 22.270332953973174 21.70392465504737 24.305001485414838 22.52078070966936 24.224389754316558 22.734796267271786 24.645676897079444 22.76782529162796 24.173722418630238 22.01182277138121 23.81136666026554 23.70196350859421 23.560085233923306 22.08100412033378 23.215743816169272 23.45936664569725 23.450019936190078 21.465305559873872 23.391460657383682 24.031123496224733 23.646400555235033 23.71061767044619 7.0 5.0 11.0 9.0 27.0 14.0 27.0 13.0 29.0 16.0 27.0 7.0 20.0 19.0 21.0 9.0 25.0 15.0 20.0 12.0 31.0 17.0 26.0 19.0 2.0 1.0 2.0 2.0 1.0 2.0 1.0 3.0 1.0 2.0 2.0 1.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.8283433672616951 0.03766692222862868 0.06276144050911694 GO:0015154 disaccharide transmembrane transporter activity molecular_function 20.703717219540398 20.976164116278863 21.712595848034407 20.273814053239207 21.346421627218497 20.363563945176693 18.960562209932068 20.986416685315124 NA 18.552806509703164 18.9026426216678 20.96571991598253 21.336541097006034 20.368706124268094 21.2075404880292 23.533783340424584 18.990601057651 17.610114742099267 19.66242361108456 19.23990223659618 21.766406525157546 18.97995726828074 18.711534613614226 20.876751466346832 20.271435076273125 19.72517948501178 5.0 3.0 5.0 3.0 2.0 5.0 NA 2.0 2.0 5.0 5.0 4.0 4.0 7.0 2.0 2.0 2.0 3.0 10.0 2.0 1.0 3.0 4.0 3.0 2.0 2.0 2.0 1.0 1.0 2.0 NA 2.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 1.0 1.0 2.0 1.0 -0.2724468967384652 0.6665990972678644 0.729111019623396 GO:0015171 amino acid transmembrane transporter activity molecular_function 22.359456676968666 25.10875685782536 21.9597967306542 24.64136436699793 21.20292922627307 24.124638235018374 21.84272793399197 25.17741263534102 22.05642566585856 24.84360096977685 21.96062050104208 25.21823423160487 23.8264041025672 25.69626547838131 23.245965071583647 25.55571314479711 22.09484501134272 25.11432975167301 21.652946938614324 24.66778986384395 21.848493047604517 23.940676819635506 22.16171806080461 26.14694792540195 22.196909155983395 24.60756633697339 14.0 48.0 9.0 42.0 10.0 72.0 10.0 51.0 17.0 59.0 31.0 55.0 19.0 82.0 18.0 62.0 5.0 54.0 9.0 53.0 16.0 76.0 18.0 50.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 6.0 2.0 7.0 2.0 4.0 2.0 5.0 2.0 2.0 4.0 3.0 2.0 3.0 2.0 5.0 3.0 -2.749300180856693 3.225641456243767e-05 0.0005099643033035255 GO:0015203 polyamine transmembrane transporter activity molecular_function 23.722229270517264 22.559647744184552 22.77226916310007 22.20241230460964 22.973540536199852 23.398109061738683 23.003061385593373 22.249748473675947 24.733053578185785 22.04018907226588 23.580990182560267 22.95879459368361 23.827745596602718 22.80088755532791 23.389335344559733 22.278871259989504 24.343425140677148 21.10736767455879 21.9418109871689 22.576244976978675 24.030003022022942 22.703749945255915 23.89162083564959 23.09389856117693 24.096860992348805 21.98776163135153 16.0 12.0 18.0 20.0 16.0 16.0 50.0 16.0 33.0 24.0 34.0 24.0 32.0 6.0 29.0 5.0 21.0 24.0 18.0 16.0 43.0 16.0 30.0 10.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 1.162581526332712 0.00268017172806849 0.006910856026093958 GO:0015238 drug transmembrane transporter activity molecular_function 21.26348094376732 21.48507641067428 17.145556521694306 20.438561482080964 20.257859747641522 21.13361792333783 18.928377478475415 20.20683193338296 21.111509102770565 20.859988717452506 23.19901123682785 23.743467785969735 22.82391114046144 21.33654353053406 19.449861175488525 20.463071382969503 20.16864741535968 19.98860306124901 21.783953360203682 22.229786853109196 20.51004289758021 19.93945043313115 19.732554420259373 20.277616878618428 20.096035867748228 20.942586823021365 2.0 4.0 5.0 4.0 5.0 5.0 4.0 6.0 10.0 5.0 15.0 6.0 5.0 5.0 10.0 5.0 5.0 5.0 4.0 6.0 4.0 7.0 8.0 7.0 2.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 4.0 2.0 2.0 2.0 2.0 2.0 3.0 3.0 -0.22159546690696175 0.27265646879500405 0.34545713000625894 GO:0015267 channel activity molecular_function 25.291278119075198 24.931656974464754 22.435561183647398 25.610371143857414 20.96913902434685 23.409722901375808 25.91884143605565 24.65585045825848 23.803556859555982 24.288191534445186 26.13260653341449 25.229826756949873 26.88490002177041 25.50938775292825 22.419862378447288 25.098095820898795 24.64924579789885 24.07013484558415 19.728898713716852 24.53719716993319 26.260805977240448 23.29311246776591 25.195610066602264 25.986602687368087 25.784831500051137 24.97510315119273 12.0 57.0 8.0 29.0 32.0 45.0 19.0 47.0 30.0 46.0 26.0 49.0 14.0 44.0 20.0 42.0 8.0 41.0 10.0 33.0 21.0 58.0 34.0 59.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 0.35962114461044337 0.9539596927720386 0.9577970205788449 GO:0015291 secondary active transmembrane transporter activity molecular_function 23.334051049595708 24.923705725261144 23.51505037424644 24.039947941404467 23.326863998278235 25.543825132570767 17.58744920829561 24.731155398629173 23.66796394499709 24.700544650729608 23.019595201645032 24.77577719898788 24.677718016281446 24.50994864120257 23.39402637018896 25.655682825840497 22.66657055675789 24.339048900672026 23.35660518461646 25.07296656666437 22.53215263175532 23.865624828489786 22.38732401948221 25.29548092111793 23.88979504471703 25.329862744127364 29.0 31.0 27.0 42.0 2.0 52.0 8.0 46.0 5.0 38.0 27.0 45.0 16.0 80.0 11.0 46.0 21.0 40.0 17.0 40.0 15.0 58.0 21.0 62.0 2.0 2.0 2.0 3.0 2.0 2.0 4.0 2.0 2.0 2.0 4.0 3.0 3.0 2.0 4.0 2.0 5.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 -1.589654675665436 0.00010962068302139599 0.000648372570666835 GO:0015294 solute:cation symporter activity molecular_function 21.816703868899783 24.73281080709949 23.10204880892223 23.679721520788217 22.96373226270362 25.43681471360301 NA 24.457347784897145 NA 24.574173848616372 19.796460334787586 24.63717445346889 21.957451293423194 24.204005773650326 23.0638409373139 25.58429312882122 17.278678352834515 24.159046614105435 18.87921651955589 24.739198150663928 21.126252838762888 23.54418046217545 19.250283126652374 25.07663721192677 21.224371365614342 25.165247855415203 19.0 21.0 22.0 34.0 NA 42.0 NA 40.0 2.0 28.0 10.0 28.0 12.0 70.0 2.0 36.0 3.0 27.0 8.0 34.0 4.0 48.0 7.0 49.0 3.0 3.0 2.0 2.0 NA 2.0 NA 2.0 2.0 2.0 4.0 2.0 4.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 3.0 3.0 -2.9161069381997073 7.612502462153449e-05 0.0006012913337194623 GO:0015318 inorganic molecular entity transmembrane transporter activity molecular_function 28.621942688384266 29.74318899737884 28.431922507467874 29.166807813895424 28.134199809890745 29.511960551454223 28.257173990637828 29.69674936723477 28.429522416591524 29.621080145058087 28.727239160314387 29.776396015364803 28.77962026415832 29.57319928900829 28.411488694717523 30.16568378120195 28.44233179464403 29.88263828785616 29.09904363202138 29.78638412762837 29.053781569044197 29.49833741921568 28.651058473139692 30.08783859560009 28.70443126945408 29.87053277148185 341.0 456.0 305.0 508.0 285.0 602.0 384.0 572.0 362.0 604.0 416.0 519.0 412.0 698.0 307.0 547.0 381.0 612.0 360.0 550.0 348.0 588.0 388.0 660.0 6.0 6.0 6.0 6.0 3.0 6.0 5.0 5.0 3.0 5.0 6.0 5.0 6.0 6.0 5.0 5.0 7.0 5.0 5.0 5.0 3.0 5.0 5.0 6.0 -1.121246308994575 3.225641456243767e-05 0.0005099643033035255 GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity molecular_function 28.651951405365143 29.669463013392377 28.40969797547513 29.076767671639104 28.06646325457632 29.357681720270623 28.30285405780348 29.619365686709752 28.518714007961197 29.55463243194693 28.82437059925049 29.75253153458128 28.750278306836325 29.52341141664505 28.44710467410287 30.053348436706447 28.4799451192648 29.84189088118223 29.178702261029247 29.72679044160677 29.072775738405195 29.44231711933211 28.683220547662224 30.012837435260128 28.70477637596456 29.78518165708088 324.0 380.0 285.0 448.0 304.0 505.0 400.0 506.0 388.0 527.0 413.0 465.0 434.0 567.0 321.0 488.0 396.0 553.0 365.0 488.0 368.0 526.0 390.0 566.0 2.0 1.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 1.0 3.0 2.0 2.0 2.0 1.0 2.0 1.0 1.0 3.0 2.0 3.0 2.0 -1.0175116080272346 4.146041132679973e-05 0.0005099643033035255 GO:0015407 monosaccharide-transporting ATPase activity molecular_function 23.943444332574426 21.95951649686932 21.717410556483387 21.089565318741275 21.873111973556323 18.84331479628697 24.03811895648121 21.97748294876117 24.322438753622755 22.01034078757469 24.6128209014564 22.83041240519566 24.30931275613473 21.44511703828506 23.85862316225585 22.64500325707653 23.46018609208825 21.168094878295108 25.068099772328363 22.628557957201203 23.241913161800298 21.255374152266395 24.115311580835808 21.203236759146524 23.47082790616264 22.79007534983882 6.0 3.0 6.0 2.0 26.0 5.0 29.0 7.0 32.0 9.0 23.0 4.0 23.0 9.0 20.0 6.0 42.0 17.0 14.0 4.0 26.0 8.0 22.0 8.0 NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.9839278357051064 0.0005320055051392492 0.0019244720881558927 GO:0015417 polyamine-transporting ATPase activity molecular_function 22.625064446920515 21.55570942693529 21.77226916310007 21.20241230460964 21.973540536199845 22.398109061738683 22.003061385593373 21.24974847367595 23.66058969147957 21.04018907226588 22.58768565377252 21.95879459368361 22.267233063602134 21.800887555327908 22.389335344559736 21.278871259989504 23.327104496613487 20.296692388250857 19.832141368310424 21.576244976978675 22.929390356435608 21.703749945255915 22.829098076555386 22.093898561176925 23.05608248869649 20.79544167927164 8.0 6.0 9.0 10.0 8.0 8.0 25.0 8.0 17.0 12.0 16.0 12.0 16.0 3.0 14.0 3.0 11.0 12.0 8.0 8.0 21.0 8.0 14.0 4.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.069355019985224 0.003892417122778628 0.009377869824763952 GO:0015420 cobalamin-transporting ATPase activity molecular_function 18.974361572815358 18.946706097868642 16.321839686452385 NA NA NA 18.928377478475415 19.084851837418746 18.619426144885075 19.68359694297288 19.69782480941394 19.54099026228053 20.59600417460109 18.53439960892279 18.063271941273094 17.728508380580827 19.58540060420521 19.09602749695064 17.091260376148984 18.5354166992792 18.37242927601508 18.704815189224906 16.828308294574597 15.8307292732554 19.17221258266062 19.729103406579878 1.0 NA NA NA 5.0 3.0 3.0 4.0 9.0 3.0 11.0 2.0 3.0 1.0 8.0 3.0 1.0 2.0 2.0 3.0 2.0 1.0 5.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.02765547494671594 0.72477122130619 0.7743276961229171 GO:0015562 efflux transmembrane transporter activity molecular_function 20.31929753300385 20.88683888424176 17.86226387859271 NA 18.138690863487547 18.9549969735056 17.58650013865006 NA 18.879068439070565 21.76019230103385 NA 21.44186868321752 22.749804554906984 21.85217509100244 21.325861741436373 18.411781986376607 18.010022666758264 17.635532370560085 17.412251557409327 21.43543184093684 20.909487523424364 17.593579874751672 19.463102945565506 20.69626581101088 18.510713101272604 21.701161635989752 1.0 NA 2.0 2.0 1.0 NA 3.0 13.0 NA 7.0 8.0 8.0 2.0 2.0 1.0 1.0 3.0 8.0 6.0 1.0 4.0 5.0 1.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5675413512379102 0.18091609383032226 0.24621950392610922 GO:0015594 putrescine-importing ATPase activity molecular_function 21.59071601204757 20.54242583072131 20.77226916310007 20.20241230460964 20.76022870030319 21.39810906173868 21.003061385593373 20.24974847367595 22.605491597081947 20.04018907226588 21.574263493082427 20.95879459368361 21.163102320303647 20.800887555327908 21.389335344559733 20.26621299493207 22.327104496613487 18.889390551612788 18.36358945650407 20.57624497697867 21.929390356435608 20.703749945255915 21.810641101936024 21.093898561176925 22.05608248869649 19.79544167927164 4.0 3.0 4.0 5.0 4.0 4.0 12.0 4.0 8.0 6.0 7.0 6.0 8.0 1.0 7.0 1.0 4.0 6.0 4.0 4.0 10.0 4.0 7.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0482901813262586 0.005583616806378765 0.012692811975156102 GO:0015595 spermidine-importing ATPase activity molecular_function 21.62896655042781 20.54417454156945 20.77226916310007 20.20241230460964 21.159337469346003 21.39810906173868 21.003061385593373 20.24974847367595 22.605491597081947 20.04018907226588 21.574263493082427 20.95879459368361 21.34667046700511 20.800887555327908 21.389335344559733 20.291419426225065 22.327104496613487 18.889390551612788 18.845153670149553 20.57624497697867 21.929390356435608 20.703749945255915 21.810641101936024 21.093898561176925 22.05608248869649 19.79544167927164 4.0 3.0 5.0 5.0 4.0 4.0 12.0 4.0 8.0 6.0 8.0 6.0 8.0 2.0 7.0 1.0 5.0 6.0 4.0 4.0 10.0 4.0 7.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0847920088583578 0.0032349119169146935 0.007931571851295751 GO:0015623 iron-chelate-transporting ATPase activity molecular_function 21.029520206480647 22.592522877895647 21.68185978016329 22.55658551247657 20.8856866314735 18.740260607653447 19.395845785596325 22.47484268162053 19.414266827624648 22.674043161427484 19.346051814911824 22.697770764906426 19.991881634826065 22.06462553574788 22.304784644543247 22.13369206518061 21.513561925689178 22.528442779099088 21.67076873436414 23.93968445176959 21.160296405564253 20.16653349365212 18.85278314704047 23.43414521969772 21.495461360019192 22.592421708917907 5.0 3.0 6.0 3.0 3.0 6.0 2.0 7.0 3.0 8.0 7.0 4.0 11.0 9.0 6.0 8.0 6.0 8.0 8.0 5.0 1.0 11.0 8.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.5630026714149992 0.0032349119169146935 0.007931571851295751 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism molecular_function 21.985897137342054 23.18224513493816 21.92738360249833 22.520442029254365 20.310871797624348 22.342967281834134 21.74163391753732 22.846518283823052 21.403501998664108 23.173735586463746 20.038995990859725 23.594202884128126 23.04230371684932 22.652164146039034 21.194029809146627 23.50223608897698 23.22540903984664 23.19136173934513 21.44375525614837 22.91643554233611 22.54478218597391 22.820702835595327 22.407643643546415 23.328142413790392 20.792118434490305 24.202540937127534 9.0 17.0 7.0 20.0 3.0 21.0 8.0 31.0 4.0 31.0 9.0 20.0 7.0 33.0 13.0 30.0 9.0 20.0 9.0 23.0 11.0 30.0 8.0 21.0 4.0 4.0 3.0 4.0 2.0 4.0 4.0 5.0 2.0 5.0 2.0 5.0 3.0 5.0 4.0 5.0 3.0 4.0 2.0 5.0 2.0 4.0 4.0 4.0 -1.1963479975961064 0.0014961642897455532 0.004424675435076897 GO:0015672 monovalent inorganic cation transport biological_process 27.61520268693265 28.33664517835793 27.146037261744777 27.45564850712194 26.708384757146874 28.048884358768053 27.32874950841536 28.40687687152682 27.58832404050704 28.421102425103715 27.76520284112459 28.4735649797406 27.771112994967986 27.811623420962015 27.382190087035088 28.7499106189648 27.60301576219398 28.740589139527565 28.163256403668953 28.334363388578804 27.97509145784842 28.18463612254784 27.726717674769464 28.38182160076313 27.686774539614138 28.53591321156517 111.0 99.0 104.0 129.0 123.0 146.0 152.0 145.0 145.0 150.0 147.0 108.0 149.0 138.0 106.0 141.0 152.0 172.0 142.0 132.0 147.0 111.0 147.0 162.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 -0.7214424914252788 0.00042856814449695465 0.0016457016748683058 GO:0015698 inorganic anion transport biological_process 20.452714823725774 22.15433868748798 19.941932709855934 23.228121433042787 21.923419507655396 23.367103263522853 NA 22.0491395592306 18.37220365875397 20.35485873983652 NA 21.088234952039766 18.803612522068786 22.497828703550915 20.621887206439247 22.1012952280194 NA 19.89976953447046 21.174781984916663 21.87966006854924 20.954278213923644 22.308701219173464 19.9183461850897 22.40598712982064 16.99712987953713 20.46591566231953 5.0 11.0 8.0 11.0 NA 13.0 1.0 7.0 NA 8.0 3.0 13.0 7.0 15.0 NA 7.0 7.0 11.0 7.0 11.0 3.0 9.0 1.0 6.0 1.0 1.0 1.0 2.0 NA 2.0 1.0 1.0 NA 2.0 1.0 3.0 1.0 3.0 NA 1.0 3.0 2.0 2.0 2.0 3.0 2.0 1.0 1.0 -1.7016238637622045 0.008551669322840596 0.0181814025807582 GO:0015821 methionine transport biological_process 19.12970120254677 22.200428603163925 19.07014656428731 22.53611800101605 16.409007952038213 19.823037238756896 20.112664832931703 23.02003472595716 21.101368131921124 22.269185304149648 17.90939386923888 22.200975198612046 17.964847568754926 22.752507349986768 19.627834553055795 21.706711151341057 17.751586280018802 21.308476757925828 18.69364365036037 22.455059141548773 NA 21.22271287480629 17.87962170654924 22.86581903196405 16.468817826944324 21.745136253231287 2.0 11.0 1.0 1.0 2.0 14.0 7.0 11.0 3.0 14.0 4.0 13.0 5.0 11.0 3.0 10.0 2.0 12.0 NA 10.0 1.0 14.0 2.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.070727400617155 8.184658360899193e-05 0.0006159890947550879 GO:0015833 peptide transport biological_process 27.35887129980422 27.65096447670497 27.28879840668152 27.94808774861724 27.39687118019775 26.587528359507623 26.967950420248428 27.233662575078817 27.26420560876237 27.358980257039928 27.703205078147217 27.744302423891746 27.754913339312445 28.015416557708182 27.12998125486266 27.56506082370832 26.989285226367183 26.90933530941436 26.98123585928441 28.249807654224306 26.985804635152498 27.460877924776828 27.51594164932324 27.75918876572303 27.89689045415627 28.09856877228705 193.0 179.0 182.0 171.0 193.0 167.0 200.0 235.0 247.0 241.0 261.0 198.0 229.0 207.0 181.0 214.0 241.0 270.0 207.0 200.0 234.0 221.0 271.0 332.0 2.0 1.0 1.0 1.0 3.0 2.0 3.0 2.0 4.0 2.0 4.0 2.0 3.0 2.0 3.0 2.0 4.0 3.0 3.0 1.0 3.0 2.0 4.0 2.0 -0.29209317690074954 0.13332693177434943 0.18549833985996442 GO:0015925 galactosidase activity molecular_function 20.743462816629282 20.751603634435483 21.54182748668399 20.01690286338077 21.24596040200805 19.28064765996588 17.720947941210394 21.396246159017576 NA 18.842376146198205 20.165305824050524 20.57270969319321 20.263369232757867 20.755714925658168 22.71008984996984 23.20789083538899 17.57740316620523 19.785488142026672 21.168587526792752 17.292602408264948 18.88576887397117 19.468019473522485 13.96154834753988 20.22145681633736 20.20133722226347 17.79022197383637 9.0 6.0 8.0 2.0 1.0 9.0 NA 3.0 6.0 8.0 4.0 9.0 9.0 21.0 1.0 6.0 5.0 1.0 2.0 2.0 1.0 6.0 4.0 2.0 2.0 2.0 2.0 1.0 1.0 2.0 NA 1.0 3.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 1.0 1.0 1.0 1.0 2.0 2.0 1.0 -0.008140817806200573 0.8535135775742164 0.8883944493850059 GO:0015926 glucosidase activity molecular_function 21.543469573001765 22.142119607031393 23.696339449670248 19.998987525882765 22.339878391912013 23.525608356167933 NA 22.424022123710827 NA 19.64094745585493 18.395810072710773 23.865556881216673 NA 20.26449370866176 17.258996362813587 22.030438407185716 18.26608904544835 19.88500894551359 21.89888915696734 20.854953242689394 NA 21.388122925175214 19.118260184860986 22.592424611309557 17.957607996075584 21.615337273556193 21.0 8.0 14.0 21.0 NA 8.0 NA 4.0 3.0 25.0 NA 5.0 2.0 20.0 3.0 8.0 3.0 11.0 NA 8.0 2.0 8.0 3.0 13.0 2.0 2.0 4.0 2.0 NA 3.0 NA 2.0 1.0 2.0 NA 2.0 2.0 4.0 2.0 3.0 2.0 2.0 NA 3.0 2.0 1.0 1.0 3.0 -0.5986500340296281 0.089632994267889 0.13412707055914325 GO:0015929 hexosaminidase activity molecular_function 21.241151095435868 21.08194268959065 22.307675176130985 13.884608684743526 18.91651353154885 20.959787350726334 16.063801682702564 20.773932641659176 NA 21.71596619125545 19.944281948884505 18.696032067180983 19.80219605009552 18.869115447249328 23.20840951163392 21.980379504325857 19.251838134003304 22.38590068838232 21.722740154713936 17.026497548120073 21.66213110307189 22.3282737866213 18.889961202340256 NA 20.93591894883256 20.198519209157734 15.0 1.0 2.0 11.0 1.0 9.0 NA 13.0 4.0 6.0 1.0 3.0 19.0 19.0 3.0 20.0 13.0 2.0 13.0 23.0 4.0 NA 6.0 5.0 2.0 1.0 1.0 1.0 1.0 2.0 NA 2.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 0.15920840584521656 0.9215372441867455 0.9380738015865078 GO:0015969 guanosine tetraphosphate metabolic process biological_process 20.4397555032567 21.23580192003009 21.55573100903206 21.100472637138537 20.36194788881552 21.509639006810737 19.9440140527857 20.143008201068078 18.92482604052084 20.43869489510703 21.16975116037165 20.713906071588866 21.10575786112921 22.126634319522246 18.156574525401197 21.86485693365829 20.315690587043928 21.77874604272274 19.696400753575283 20.638823159512587 18.51360937173284 20.347983007887038 19.73301667957997 21.85328804969684 21.428492622443645 20.363306043071066 6.0 6.0 6.0 11.0 7.0 6.0 4.0 5.0 11.0 3.0 12.0 8.0 2.0 19.0 6.0 12.0 6.0 5.0 4.0 5.0 4.0 8.0 13.0 4.0 NA NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA NA NA 1.0 NA 1.0 NA -0.7960464167733932 0.02092133533779403 0.038284203081476474 GO:0015976 carbon utilization biological_process 26.250487138209824 26.38274744529561 27.631287749716343 26.149612196958337 27.784929318395978 26.4969915728716 23.723068798265988 26.236729402636385 23.629693130315186 26.401112450786115 24.10885823330912 26.607806806918955 25.094879418412003 25.305558465277553 26.327927304967226 26.930988963506888 24.403722923319894 25.528602031152055 27.072716542518787 27.149638563880693 26.59436722897531 26.324245404672546 25.969603898113817 26.27159695191691 24.484530677314787 26.237580613228502 75.0 49.0 93.0 83.0 32.0 57.0 34.0 48.0 25.0 54.0 41.0 40.0 61.0 85.0 28.0 63.0 77.0 76.0 71.0 69.0 58.0 59.0 37.0 57.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.13226030708578662 0.27265646879500405 0.34545713000625894 GO:0015980 energy derivation by oxidation of organic compounds biological_process 26.98300996586391 24.2253416259312 25.92299740246014 23.356647368837013 24.595393262985173 22.980058901151004 26.753257482478837 24.424206815013523 26.539653524023237 23.393709791508666 27.57856220832611 25.50678316991829 27.849554913236442 23.98094981979383 26.41068310521563 24.03086563941453 26.75588139329988 22.903974349107283 27.16628633325568 25.22186447172309 27.74565198405297 24.171671029069554 26.83014422490995 22.409751850341877 27.182570167379552 24.83798081896861 30.0 15.0 17.0 9.0 63.0 23.0 64.0 20.0 80.0 43.0 68.0 16.0 63.0 17.0 54.0 19.0 103.0 30.0 71.0 17.0 65.0 10.0 71.0 34.0 2.0 1.0 1.0 2.0 3.0 1.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 1.0 3.0 1.0 3.0 3.0 3.0 2.0 3.0 1.0 3.0 2.0 2.75766833993271 6.784570247173055e-05 0.0005498145239267514 GO:0016020 membrane cellular_component 29.350360550741573 29.82810826366041 29.062442566817193 29.357513569253157 29.141698655558876 29.670476277514442 29.130047166865012 29.48534713293736 28.950539250058302 29.523923230659108 29.610902362556466 29.70951934759937 29.693484744927826 29.77217739508421 29.19090688286027 30.168574355333504 28.74220682216669 30.27406161674201 30.059038629522995 30.01275574024291 29.332253584516977 29.39866184746603 29.11908318785559 30.327157685921744 29.6226267157152 29.79837012847889 554.0 583.0 496.0 641.0 440.0 730.0 517.0 792.0 565.0 798.0 651.0 641.0 636.0 963.0 436.0 921.0 782.0 805.0 547.0 623.0 560.0 864.0 610.0 851.0 4.0 2.0 1.0 3.0 5.0 5.0 3.0 4.0 4.0 4.0 5.0 2.0 4.0 4.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 5.0 5.0 -0.47774771291883766 0.003892417122778628 0.009377869824763952 GO:0016043 cellular component organization biological_process 29.60785803245106 30.06550103241315 29.62080136391621 29.51818825685316 29.195156422349445 29.44431193223843 29.217879395967607 30.11074545208928 29.197793720111452 30.10994051214013 29.36888820566844 30.271083457820183 29.70623995888257 30.129318194451688 30.262710915900875 30.44253658613809 29.044090780973555 29.981674125302497 29.46063321727292 30.211291058415213 30.24242335912077 29.88751220132609 30.00567840427641 30.37603108779876 29.253392697026683 29.962967282618948 350.0 263.0 308.0 412.0 278.0 424.0 292.0 370.0 412.0 439.0 423.0 432.0 436.0 524.0 314.0 463.0 503.0 472.0 377.0 358.0 417.0 464.0 371.0 449.0 9.0 7.0 8.0 8.0 10.0 7.0 10.0 8.0 9.0 8.0 10.0 8.0 10.0 7.0 9.0 8.0 9.0 9.0 9.0 8.0 10.0 7.0 10.0 9.0 -0.4576429999620899 0.011074437676156606 0.022291771322328135 GO:0016051 carbohydrate biosynthetic process biological_process 28.09418887759839 28.21584423331007 28.430571722277307 27.44400567727284 27.944325215671924 27.805037755813185 27.882221231272244 28.434339732504352 27.27377222444673 28.303806398181656 28.075321148152145 28.88572437564817 28.111996829972266 27.967872664556225 28.02573801492811 28.546070967331506 27.614090331388642 28.184572418002315 28.615763091435298 28.33872704403705 28.69142364874137 28.432307979759607 27.704982328193456 27.66954440258824 28.129163052045158 27.94943424383679 111.0 76.0 97.0 90.0 195.0 162.0 211.0 163.0 244.0 173.0 253.0 102.0 234.0 148.0 207.0 141.0 359.0 205.0 177.0 114.0 203.0 114.0 236.0 162.0 4.0 4.0 4.0 4.0 4.0 5.0 5.0 5.0 4.0 4.0 5.0 4.0 5.0 4.0 4.0 4.0 5.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 -0.12165535571167752 0.4529203011037244 0.5347630423627702 GO:0016052 carbohydrate catabolic process biological_process 28.755781906829128 29.710377741089268 29.34158221186757 29.14061935588496 29.054896857919502 29.851263249562336 28.133695222388617 30.01430489993589 27.57769623727601 29.48169761363041 28.501347507793568 29.557336683294462 28.5581015859792 29.08928838575275 29.51723342538422 30.160196601468872 27.969288715443344 30.20623659328677 29.795300923209734 29.872246453983998 28.614996383679337 29.634826848501266 27.860155432302694 29.60870509704537 28.224158885888176 29.407342023203913 249.0 204.0 268.0 228.0 189.0 307.0 167.0 245.0 196.0 266.0 220.0 181.0 305.0 299.0 181.0 235.0 355.0 273.0 233.0 237.0 176.0 212.0 176.0 246.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 -0.9545958342601395 0.0006583371695572323 0.0022696264851033866 GO:0016053 organic acid biosynthetic process biological_process 29.67417624729965 30.7396494705761 29.86054525477758 29.863590605922607 29.521480964099695 30.57501388090657 29.19780927118745 30.739752721783727 28.883658615890198 30.57651904241456 29.633807116317357 30.855754121728946 29.693132616057426 30.348100292717337 30.28354111491472 31.189205754003677 29.20252347333989 31.369996464712127 30.648538360525034 30.75394493597088 29.423943825987763 30.370427185147072 29.323856445960523 31.08430069482551 29.428315010484642 30.515603902595238 571.0 701.0 626.0 892.0 508.0 1150.0 522.0 1119.0 656.0 1140.0 760.0 888.0 744.0 1228.0 528.0 1342.0 923.0 1035.0 721.0 949.0 745.0 1199.0 653.0 1107.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.0654732232764523 0.0001748865925420931 0.0008236168584623857 GO:0016070 RNA metabolic process biological_process 29.697085945507716 30.40387620031197 29.39196440158023 29.90425463681572 29.211848005337767 30.35583179912005 29.35910447534501 30.443426257899194 29.983690524952173 30.138421442572884 30.08156492162125 30.459233105796102 30.02200299352046 30.46552117742803 29.846743880663013 30.699832206804857 29.07359080309288 30.35154892632733 30.05106928790152 30.63429725284989 29.32404531801836 30.088914513727865 29.80309304612843 30.846187284790158 29.729138982263212 30.177963210960986 928.0 1224.0 855.0 1435.0 1106.0 1606.0 1261.0 1487.0 1511.0 1663.0 1445.0 1359.0 1348.0 1769.0 930.0 1773.0 1869.0 1715.0 1031.0 1321.0 1308.0 1813.0 1354.0 1511.0 10.0 10.0 9.0 10.0 10.0 10.0 8.0 10.0 8.0 10.0 11.0 10.0 7.0 10.0 9.0 10.0 10.0 10.0 8.0 10.0 8.0 10.0 9.0 9.0 -0.706790254804254 8.637667594722788e-05 0.0006159890947550879 GO:0016071 mRNA metabolic process biological_process 24.731983365421748 23.318852310598164 22.73773317930611 22.32536488822824 23.26260213311873 23.91696024360054 24.567744438142142 22.33022222104154 25.10784957156449 22.454625233239387 25.27784022931821 23.165053453649424 25.282273825589897 23.485598429825483 24.676411153932065 23.86807020084232 23.782434120156584 23.324092867751716 25.429574146528076 23.65009924441357 24.23515902250396 22.367206329631987 25.027810711929426 24.257800324002705 25.03710679070468 22.904013215217155 16.0 11.0 8.0 24.0 41.0 13.0 53.0 15.0 48.0 31.0 41.0 14.0 40.0 29.0 26.0 29.0 79.0 28.0 25.0 9.0 54.0 28.0 45.0 17.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.4131310548235838 0.0018227351663913985 0.005134928866041682 GO:0016072 rRNA metabolic process biological_process 24.60531630539012 25.758530817856606 24.95960363475436 25.235146190023045 24.463987845963093 25.233554634413533 23.946087548030572 25.89699211652761 24.78276938571707 25.40646015689536 25.003787254929403 25.783737216829557 24.95901966152576 26.293166890559373 25.20269094002637 26.07119084869045 23.28226504729016 25.84564738302949 24.552156016277102 25.68931191297533 24.51320976358057 25.37370882772982 24.434293850646178 26.37758519856185 24.19426649066281 25.24347178763464 52.0 71.0 46.0 77.0 41.0 83.0 33.0 76.0 60.0 86.0 62.0 78.0 53.0 100.0 34.0 96.0 57.0 64.0 52.0 63.0 37.0 98.0 59.0 68.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 -1.1532145124664872 3.225641456243767e-05 0.0005099643033035255 GO:0016075 rRNA catabolic process biological_process 20.537892111954697 20.419138049620337 14.507310257906935 17.880427290695998 NA NA 22.048785924767426 19.44811652439124 20.868539338451523 19.972061192358964 21.299068426513962 20.453693023460005 20.454137203773676 20.98622176651703 18.88741867744206 20.707697799508306 20.80233411859449 20.544175622780376 19.83131635203657 18.786200591873012 19.72321424385047 NA 19.67140553246832 22.00798897703001 20.52236206071564 19.221473530692855 1.0 3.0 NA NA 7.0 5.0 4.0 4.0 6.0 4.0 5.0 6.0 2.0 5.0 6.0 6.0 4.0 2.0 1.0 NA 4.0 5.0 5.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.11875406233436081 0.6726547923771844 0.7338052280478375 GO:0016114 terpenoid biosynthetic process biological_process 26.03593021894769 26.07116260414832 25.341608529383464 NA 16.389452525881946 20.766050485954466 25.661185044852648 25.941954456770496 26.822617762399588 27.27453810794713 25.953048172467717 26.696678517840052 26.456825730623976 25.278381665403188 26.5023587579914 24.958716731411762 25.78176923101807 26.01740034066989 26.11998792663108 26.263505702507786 26.04853522638657 25.416693351484014 26.65563732638276 25.732812597371662 25.670022877244712 26.787319710668093 21.0 NA 1.0 4.0 32.0 30.0 60.0 37.0 38.0 30.0 42.0 21.0 44.0 20.0 35.0 29.0 34.0 41.0 31.0 25.0 44.0 25.0 38.0 30.0 NA NA NA 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.035232385200629324 0.8055405886674939 0.8462244567820139 GO:0016149 translation release factor activity, codon specific molecular_function 23.58194643130762 25.253389988597032 24.3035500221917 25.08695049560991 24.765664014302 24.97007814413527 22.55242191872981 25.32042253040677 22.334208739891587 24.46335668009422 23.912216290599986 25.340968237752445 23.83926139670959 25.74380780962107 23.223966985091252 25.44427135554843 22.704256274746925 24.972314756064357 22.766594968458648 25.159224261515302 23.737137512997176 25.23527671898069 22.538806665133954 25.967338880275122 23.8738893704625 24.664530112866554 34.0 46.0 42.0 48.0 13.0 56.0 16.0 43.0 25.0 56.0 32.0 52.0 25.0 61.0 17.0 58.0 25.0 55.0 36.0 46.0 15.0 53.0 33.0 56.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.671443557289411 5.312128159411724e-05 0.0005099643033035255 GO:0016151 nickel cation binding molecular_function 23.07959721046311 23.782881161537386 17.496838881722955 NA NA 20.10700843857204 21.879039584781466 22.019363920328196 18.027018535676287 22.794122670676394 22.642984444145817 22.508000939520088 23.780737083355287 23.84546499901693 19.832318939936762 23.19247454488453 22.8045211436663 24.783888140464892 25.561130379477916 22.2278859055452 22.078608294932145 23.59912765410925 21.08777253342384 24.10695954014265 22.897691818616142 25.60155412605735 2.0 NA NA 1.0 7.0 10.0 1.0 12.0 7.0 12.0 15.0 11.0 4.0 13.0 9.0 22.0 23.0 12.0 9.0 16.0 8.0 9.0 10.0 19.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7032839510742761 0.09404066637444118 0.1379524750629327 GO:0016154 pyrimidine-nucleoside phosphorylase activity molecular_function 23.6675241066102 21.58951080985629 20.669699572742665 20.337426096360602 25.35968482342361 23.983937953035998 20.848032324447182 20.8119485582934 NA 19.186985402831464 NA 21.888442890786518 22.169410614604143 20.970530524503783 18.407685195595835 19.82929063274408 NA 19.25497375007617 24.99672664922606 22.607226658999487 23.65983098181671 19.818078228740216 24.31938958209209 20.66249824236888 19.131849838726076 19.99697930944765 6.0 5.0 27.0 23.0 4.0 9.0 NA 4.0 NA 5.0 17.0 10.0 3.0 5.0 NA 5.0 16.0 13.0 21.0 4.0 22.0 11.0 2.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.078013296753909 0.2008251226951454 0.2703665082238851 GO:0016209 antioxidant activity molecular_function 26.61101825842239 26.610302513233805 25.90167591008423 24.72517290481657 21.727228989756465 23.852243170924748 26.65412031277821 26.151670402359194 26.166140135558948 27.880730379442447 26.80055931473443 27.37086845020733 26.93769131368838 26.71119961776165 25.88829370296705 25.810182982090925 25.247569394225195 25.508385725745363 27.55381587558865 26.68925029101221 26.88095655988512 25.61830622140173 27.750589227446426 26.95675625561276 26.40889485650556 27.46165902687517 28.0 18.0 4.0 20.0 39.0 61.0 63.0 50.0 57.0 53.0 47.0 29.0 49.0 49.0 37.0 44.0 62.0 44.0 43.0 36.0 51.0 45.0 49.0 41.0 3.0 3.0 NA 3.0 5.0 4.0 4.0 3.0 4.0 5.0 5.0 2.0 4.0 4.0 5.0 4.0 3.0 4.0 4.0 3.0 4.0 4.0 5.0 4.0 0.00071574518858597 0.8173613313851769 0.8543274217493305 GO:0016260 selenocysteine biosynthetic process biological_process 24.879082467771802 25.859224490539866 24.544813538744588 25.40120569472744 24.677728835070386 25.933278682164545 24.737762994427037 25.685444324423532 25.52455133933805 25.34208964478405 25.500082401645642 25.922408062037864 24.888439271300346 25.899880320651786 24.725864647584768 26.31981279386481 23.83779254000146 25.97748069207293 25.334775221685344 26.141348642583278 23.972506026480414 25.71676278652484 24.946764759608804 26.17968569012806 24.85528126884227 25.402242321965442 18.0 31.0 27.0 27.0 27.0 33.0 40.0 40.0 35.0 36.0 27.0 23.0 33.0 36.0 19.0 42.0 41.0 44.0 27.0 33.0 38.0 41.0 28.0 40.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9801420227680637 0.0001386794054294884 0.0007006959432226783 GO:0016301 kinase activity molecular_function 28.682445867693552 28.749757923580745 28.317197241287264 28.080808226838823 28.26707901634407 28.59650879310348 28.5495794054414 28.968010398862877 28.715731554521017 28.61768239942161 29.02835375793881 28.896587114289154 28.93850365682264 28.782325561794554 29.048501032750416 28.979481412464928 28.02700329324881 28.82168779346469 29.28765511494037 28.832619378617807 28.37845772446756 28.38309223781593 28.477381429083323 29.024000375158238 28.609815704185138 28.74719693546559 287.0 290.0 286.0 305.0 328.0 478.0 346.0 388.0 410.0 418.0 415.0 343.0 413.0 443.0 302.0 456.0 496.0 477.0 328.0 322.0 363.0 425.0 402.0 437.0 17.0 15.0 14.0 15.0 18.0 19.0 17.0 14.0 19.0 18.0 21.0 20.0 20.0 21.0 19.0 21.0 20.0 19.0 19.0 14.0 18.0 19.0 19.0 18.0 -0.06731205588719291 0.4529203011037244 0.5347630423627702 GO:0016407 acetyltransferase activity molecular_function 29.08436608273753 27.98044681451164 28.680481183443842 26.39062091264309 28.659677417485085 28.08485469249311 28.77587766007679 27.95854276917072 29.039167513675732 28.353178877898873 29.024748218172675 28.00182906106938 29.222138090327093 26.728364716580053 29.676962310232224 28.046660805476225 28.6477217709128 28.052952927762572 29.766015866352163 28.44957339818432 28.951577146434264 28.193527517554802 28.89325327167046 27.89266337640302 29.11863115904934 28.353756538690554 158.0 63.0 154.0 143.0 173.0 158.0 195.0 152.0 200.0 164.0 184.0 85.0 256.0 133.0 147.0 141.0 240.0 215.0 202.0 137.0 195.0 132.0 184.0 159.0 5.0 4.0 4.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 4.0 3.0 5.0 5.0 5.0 3.0 4.0 4.0 5.0 5.0 5.0 5.0 1.1039192682258907 3.225641456243767e-05 0.0005099643033035255 GO:0016408 C-acyltransferase activity molecular_function 28.90812096023719 27.11231081138937 28.139371822086158 25.092393922377273 28.37008492158553 27.539609009542406 28.71071069061245 26.909921211398128 29.09808639890901 27.11350425704135 29.04104697775875 27.143024391843767 29.180919420430346 25.241456550027976 29.47113916024477 27.24869454329544 28.41174252047421 27.28719493090146 29.67882395712932 27.95172749894449 28.50452933865028 27.28151055888548 28.49853037494349 27.01773665513066 28.91631809761974 27.33328274854567 99.0 29.0 97.0 84.0 130.0 77.0 161.0 74.0 141.0 89.0 140.0 37.0 202.0 72.0 109.0 72.0 179.0 157.0 133.0 64.0 142.0 71.0 132.0 84.0 2.0 1.0 2.0 1.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.7958101488478206 3.225641456243767e-05 0.0005099643033035255 GO:0016417 S-acyltransferase activity molecular_function 25.415664800709337 23.569049217008466 22.82074105354405 18.8530105058597 22.006401925780416 21.155921824506592 25.027867180463023 23.91302455352702 24.23590182129481 25.0302714762842 25.24322866230498 24.926401347383326 26.89037254581164 22.853311672393733 26.848591540983943 21.51870384965805 24.24162760598401 23.76318602414331 25.010522245518914 23.378064410056023 25.35760380261189 21.449777690513155 25.439884454559866 22.249201531724886 25.404446963354125 24.32460917242716 16.0 3.0 5.0 10.0 21.0 24.0 28.0 26.0 30.0 32.0 34.0 13.0 22.0 7.0 24.0 18.0 41.0 19.0 32.0 7.0 38.0 11.0 33.0 17.0 3.0 3.0 2.0 4.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 3.0 4.0 1.0 4.0 3.0 4.0 2.0 4.0 1.0 4.0 3.0 4.0 3.0 1.8466155837008706 0.004669131805023211 0.010994483948432015 GO:0016433 rRNA (adenine) methyltransferase activity molecular_function 21.858152196113352 23.236654643521966 23.567181805701928 21.978803780706688 22.505456594966827 22.918986248705906 18.87166063809732 23.435358886494647 18.348388273787595 22.713921625770716 21.282107993223807 23.21329485245307 22.014373419548935 23.655022100625114 22.93059115879598 23.67127944687945 19.72808107721201 22.52744617021709 21.516925111882955 23.43038463711068 22.368149020329266 22.77674289478989 18.41416616314469 24.108164424658106 20.938080974065517 23.16547103627169 11.0 13.0 11.0 19.0 2.0 22.0 2.0 15.0 9.0 21.0 9.0 12.0 8.0 23.0 2.0 18.0 14.0 21.0 9.0 12.0 4.0 29.0 12.0 17.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 1.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 -1.3785024474086143 0.0014961642897455532 0.004424675435076897 GO:0016434 rRNA (cytosine) methyltransferase activity molecular_function 19.406108858250807 20.854504325246864 18.09604041076852 20.388799613179113 NA 21.078376330265442 19.36844232880052 20.84922679938269 18.64189406923416 19.74461772654922 20.878435737981736 20.368221960532487 19.92151545190319 20.828597277390138 19.434724918799066 22.339622312269913 17.829074524326977 19.60674509968684 19.539620108963547 19.050788949856056 18.533127818251035 17.251344564420073 18.331087267508842 22.427878290084816 19.846277193370415 19.485091418235733 2.0 9.0 NA 8.0 5.0 9.0 2.0 7.0 9.0 9.0 6.0 7.0 4.0 13.0 3.0 6.0 4.0 3.0 3.0 2.0 4.0 15.0 6.0 5.0 2.0 2.0 NA 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 1.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 -1.4483954669960575 0.031232244921543854 0.05413589119734268 GO:0016435 rRNA (guanine) methyltransferase activity molecular_function 19.240017572826808 21.223579417556863 18.160204355796424 20.246507941212364 19.295104808877216 21.323587027646862 18.230993567593387 20.571365142912537 19.76359558809481 20.58827942090849 20.007734205494145 19.88599196553204 19.080235315987625 21.173870925402397 NA 20.712887248292024 17.896975132315138 21.03398809981043 19.740968400317982 22.987410329169965 19.890625313006574 20.48241477325628 16.87207707945937 21.843378039399404 19.70778831947855 20.642890241261327 2.0 4.0 1.0 10.0 2.0 7.0 1.0 5.0 5.0 5.0 4.0 7.0 NA 11.0 3.0 13.0 9.0 8.0 8.0 5.0 3.0 9.0 5.0 4.0 2.0 1.0 1.0 3.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 NA 3.0 2.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 -1.9835618447300547 8.184658360899193e-05 0.0006159890947550879 GO:0016453 C-acetyltransferase activity molecular_function 28.567549990029026 27.078914101540338 28.134352468465966 25.092393922377273 28.36704374983225 27.539609009542406 28.292121600472907 26.909921211398128 28.427873985013857 27.11350425704135 28.47454753190929 27.132618857642765 28.647336894913522 25.238396892239685 29.00868786006857 27.246214030139193 27.895926962981285 27.28719493090146 29.581091964830648 27.726225111565327 28.479629348124003 27.28151055888548 28.29425890578208 27.011444964650124 28.39639764906568 27.331064554227748 92.0 29.0 95.0 84.0 109.0 77.0 125.0 74.0 117.0 84.0 113.0 36.0 159.0 69.0 89.0 72.0 157.0 136.0 117.0 64.0 121.0 69.0 110.0 82.0 2.0 1.0 2.0 1.0 3.0 1.0 2.0 1.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 1.0 3.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.4886358884886874 3.225641456243767e-05 0.0005099643033035255 GO:0016462 pyrophosphatase activity molecular_function 31.010412560911693 31.159282755062986 30.76031469878203 30.445347981268238 30.60632626343251 31.091254804921412 30.626676227798427 31.113419937248416 31.04728068447389 31.154950074646514 31.115942740720172 31.31507082649253 31.03771897468173 30.90343250490418 31.087453741681145 31.371525757109822 30.570701506589717 31.19221158458279 31.43649614466391 31.206775562124577 31.454577335070443 31.213537647663532 31.08686568526445 31.327266428400982 30.95968512308977 31.351245365945573 964.0 985.0 765.0 1233.0 825.0 1305.0 1046.0 1239.0 1081.0 1340.0 1069.0 1206.0 1159.0 1405.0 841.0 1283.0 1177.0 1443.0 918.0 1174.0 953.0 1300.0 1034.0 1416.0 5.0 5.0 4.0 5.0 5.0 4.0 6.0 4.0 6.0 5.0 6.0 6.0 6.0 5.0 5.0 7.0 6.0 5.0 5.0 4.0 6.0 5.0 6.0 7.0 -0.14887019415129288 0.0832645166635504 0.12534875367444018 GO:0016491 oxidoreductase activity molecular_function 31.949545883855233 32.07076021199445 31.591905950726137 31.062689558394176 31.716656251966945 31.8197852371801 31.72308839016345 32.24707063035602 31.826310402087067 32.42174832684594 31.98952848022007 31.989077912403907 32.06773401078771 31.52509029615825 32.28979478920946 32.23547510020884 31.87711166319879 32.33476374102301 32.15225083332004 32.09521979486321 32.039693379815624 31.92839071129065 31.944814052674108 31.834139007562946 32.02437411513652 32.68749270664823 1178.0 829.0 1114.0 1334.0 1368.0 1588.0 1590.0 1583.0 1561.0 1513.0 1569.0 1113.0 1818.0 1467.0 1255.0 1484.0 2041.0 1679.0 1595.0 1302.0 1684.0 1315.0 1540.0 1597.0 22.0 19.0 20.0 22.0 25.0 23.0 25.0 23.0 25.0 26.0 26.0 20.0 23.0 22.0 25.0 23.0 23.0 22.0 23.0 20.0 28.0 21.0 25.0 25.0 -0.12121432813921373 0.4189234409463829 0.5022252202700153 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors molecular_function 29.753260677430358 30.24732947569443 29.366336306447433 28.76216073503741 29.184016320519024 29.29610644266674 29.031139165292025 30.518899626496612 29.67872674527136 30.716074190261093 29.44989158539702 29.989406029843522 29.748204894697363 29.33236413248435 30.26203361655541 30.360501804573694 30.091267217167395 30.963646676453532 30.04969553166789 30.06654105116407 30.043030328327287 29.922119140004487 29.898385250449714 29.75365072872455 29.68733628777811 31.28487000810377 299.0 223.0 334.0 323.0 286.0 400.0 306.0 382.0 307.0 340.0 331.0 281.0 442.0 374.0 281.0 386.0 465.0 407.0 396.0 334.0 327.0 333.0 342.0 402.0 6.0 6.0 6.0 4.0 6.0 5.0 5.0 6.0 6.0 5.0 6.0 6.0 5.0 3.0 5.0 5.0 6.0 7.0 6.0 4.0 6.0 4.0 5.0 5.0 -0.49406879826407035 0.14891467317876572 0.20512749682902828 GO:0016615 malate dehydrogenase activity molecular_function 27.283925371453805 27.675887809710805 26.61171115571281 22.923713937330852 22.44777913233593 22.60412457625675 26.58599877589614 28.05143582445752 26.524264534100546 28.461866700320677 26.757764377564182 27.823667004306568 27.43938061419591 26.611475331955038 27.49237695758577 27.53362093623574 28.147462428607497 28.557113367525435 27.859280566437093 27.02520701365253 28.000212841022968 26.795606781479826 27.688982342170334 26.36865721083206 27.11597683174137 29.257559456547185 20.0 11.0 10.0 10.0 21.0 25.0 25.0 29.0 24.0 22.0 22.0 15.0 30.0 18.0 28.0 25.0 32.0 27.0 32.0 23.0 27.0 28.0 22.0 32.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.39196243825699995 0.6441672226837103 0.7073013587238495 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor molecular_function 29.33929496524704 29.726470152392768 28.979447409883992 28.39721678630348 29.00046572370646 28.864707688927922 28.661296579269106 29.95969607839559 29.292018835069452 30.12515302345736 29.072555889054406 29.453688411989713 29.327934687676983 28.890078875846434 29.84336586951123 29.819118688018182 29.612811896742915 30.37781220615592 29.498790110571505 29.69084192540512 29.540276220517487 29.46150682744173 29.480079132678995 29.276198415410065 29.365150212096324 30.721796030909022 238.0 186.0 280.0 282.0 218.0 314.0 227.0 294.0 232.0 266.0 257.0 233.0 333.0 320.0 210.0 310.0 345.0 325.0 313.0 277.0 257.0 277.0 265.0 312.0 34.0 24.0 26.0 28.0 29.0 31.0 26.0 25.0 30.0 31.0 28.0 27.0 33.0 31.0 29.0 30.0 42.0 32.0 30.0 24.0 29.0 33.0 27.0 29.0 -0.3871751871457292 0.29869755599497017 0.3712893923124729 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor molecular_function 29.880893766193036 30.47704792813328 30.416282589641362 30.02539197752758 30.584421965134354 30.519786567725397 29.675302886314626 30.570602632840615 28.936046059804355 30.501784955486073 29.41500711311305 30.382730732694725 29.36380147009435 29.848165219771204 30.061900463871336 30.80386192380841 29.49487736988873 30.556696290291985 30.48979375463532 30.74991534773866 30.125558676830806 30.61664384773013 29.20473950801288 30.25759575692911 29.69327382875657 30.603163239317226 161.0 113.0 188.0 211.0 159.0 166.0 190.0 161.0 172.0 176.0 193.0 139.0 188.0 172.0 144.0 165.0 239.0 204.0 214.0 157.0 216.0 161.0 165.0 180.0 5.0 6.0 2.0 5.0 6.0 5.0 6.0 6.0 6.0 8.0 7.0 7.0 6.0 7.0 8.0 6.0 7.0 7.0 7.0 4.0 7.0 6.0 4.0 7.0 -0.5961541619402446 0.00268017172806849 0.006910856026093958 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor molecular_function 24.70473292410048 23.51817234134705 24.448445066328745 22.696011362229275 25.698475194165397 24.67501859728117 24.25741274493536 22.342740839710803 21.549100397779327 22.991997646434964 23.725063108273808 23.295151069414352 24.261291956742138 22.8349711853803 24.18144114571977 23.383092995844546 22.382474696793555 22.47890877462468 26.301734669962073 23.946020405495506 25.124915756979647 21.597496518361393 24.892727660598197 24.60311480214127 24.159263815703397 24.06431104979405 25.0 13.0 40.0 43.0 25.0 17.0 13.0 22.0 15.0 25.0 18.0 15.0 23.0 29.0 12.0 17.0 47.0 34.0 38.0 10.0 44.0 40.0 21.0 26.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 1.1865605827534296 0.03766692222862868 0.06276144050911694 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors molecular_function 28.55477838727759 27.39301416962089 27.44757118573523 22.06877790824608 24.105432092762594 23.720483441832 28.132182179910174 27.671457481223698 28.429403167628518 28.123494742626914 28.78806536492064 28.15916002555037 29.415292963293773 26.56576692541909 28.835977699764506 27.284211315873176 28.44874385560084 27.93812227639693 28.449156347327037 27.181875074977068 29.23515556601961 27.27021469633184 28.63854771617638 26.183743922654273 28.692155058655853 28.503364278721577 73.0 13.0 41.0 37.0 118.0 66.0 139.0 83.0 141.0 87.0 135.0 50.0 144.0 73.0 114.0 73.0 158.0 105.0 128.0 67.0 137.0 57.0 124.0 85.0 5.0 3.0 5.0 7.0 5.0 3.0 8.0 4.0 6.0 5.0 7.0 6.0 6.0 3.0 6.0 5.0 6.0 6.0 7.0 4.0 6.0 6.0 7.0 4.0 1.1617642176566996 0.00268017172806849 0.006910856026093958 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor molecular_function 24.859750517615765 22.97934906370921 23.08652416808724 19.803973363552448 21.802386317693696 19.280286060501254 25.42989618351604 22.618871409927827 25.024995622371396 23.68978031258595 25.23991889335636 23.833089758586606 25.528464902637246 23.02352557250737 25.508803886036574 23.34371075517209 24.558405564345158 22.8210112370976 23.95429944486764 23.745243594574838 22.879078619712534 22.085288045273884 24.390803791838533 22.419622177752718 25.997762495453138 23.523850079128408 15.0 2.0 5.0 2.0 28.0 13.0 28.0 17.0 32.0 20.0 42.0 12.0 36.0 18.0 35.0 15.0 29.0 31.0 16.0 11.0 19.0 11.0 38.0 17.0 4.0 1.0 2.0 1.0 4.0 4.0 3.0 4.0 4.0 5.0 6.0 5.0 4.0 6.0 2.0 4.0 7.0 6.0 3.0 4.0 3.0 3.0 4.0 4.0 1.880401453906554 0.0032349119169146935 0.007931571851295751 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor molecular_function 26.50481035178278 24.262200913489906 24.764314209805523 21.608838751212435 16.552188686596196 19.311413117613565 26.093395220381087 23.35652167738513 24.869304218047155 24.29193268165695 27.08524083239481 25.887549024415158 27.71509862087482 24.171888716625585 25.149531362655352 23.72785127032001 25.517922291811658 24.116522172249013 26.831384998429648 24.104764194957923 27.823512594652605 24.188977418407852 26.798321785735645 23.219877800688515 26.42678663310421 25.465420817314246 15.0 7.0 1.0 6.0 27.0 15.0 26.0 18.0 30.0 18.0 23.0 8.0 23.0 14.0 17.0 16.0 41.0 22.0 30.0 12.0 25.0 9.0 21.0 25.0 3.0 2.0 1.0 1.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 3.0 2.242609438292874 0.0022136919545913893 0.006045268182341475 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors molecular_function 28.54422785997737 27.718286779379053 26.77171747646008 26.963605899783765 26.56627650336559 27.56491372019493 28.979249812733368 27.05957439890717 29.054342409332808 27.56320119122654 29.34597111711939 28.08487563897457 28.649088250462302 27.100963013901893 28.940926398771072 28.062456837874013 28.36359361816033 28.043972822894077 28.077451283503088 28.263361274131444 26.791070306664768 27.635484930459967 28.4497241724442 27.889461979993943 29.31241404525052 27.69428456514022 50.0 36.0 43.0 62.0 43.0 76.0 67.0 68.0 55.0 78.0 68.0 51.0 74.0 61.0 44.0 64.0 68.0 64.0 64.0 67.0 73.0 53.0 54.0 69.0 5.0 3.0 2.0 2.0 2.0 4.0 3.0 4.0 4.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 4.0 4.0 2.0 3.0 3.0 4.0 2.0 4.0 0.8259410805983158 0.04964722965745621 0.07872902492059129 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor molecular_function 28.47824825569251 27.664894523469677 26.49957504263791 26.95310649345763 26.56471630837139 27.563950425590612 28.962566013338733 26.96342684234857 28.981979414978053 27.407191897556444 29.31366617574709 27.944940385092305 28.568940042097392 27.06329032085114 28.88031677199821 28.052423510284036 28.34513178068205 28.0268392415863 28.002059009441126 28.2231830952183 26.34858821135487 27.60068729620129 28.290896023845548 27.88025138466092 29.290473807075823 27.58953248417933 38.0 34.0 42.0 61.0 38.0 58.0 52.0 52.0 44.0 61.0 55.0 41.0 55.0 53.0 36.0 53.0 55.0 53.0 52.0 58.0 57.0 46.0 45.0 51.0 3.0 1.0 2.0 2.0 3.0 3.0 3.0 2.0 3.0 4.0 5.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 5.0 4.0 4.0 3.0 4.0 4.0 0.8133537322228328 0.05674681648938142 0.08919398863822169 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors molecular_function 23.48487776954815 23.965325979730128 23.17603850998485 23.21037467436421 25.753007465688864 25.01931513802536 19.72685004105205 24.57659022968488 23.53513418500815 23.96897757820253 23.043749408676504 23.173818475773924 24.13025556464356 22.83564786651384 23.07559140203241 24.08837334617241 20.894130834276105 23.165105629012853 22.47815187355375 23.75913891748864 23.23618464399425 23.365520820033197 22.30917423427848 24.768300337190546 21.567095792960068 23.69933011235464 4.0 5.0 36.0 44.0 6.0 21.0 20.0 23.0 20.0 11.0 23.0 10.0 11.0 20.0 7.0 16.0 17.0 18.0 23.0 12.0 21.0 14.0 6.0 12.0 2.0 1.0 1.0 1.0 3.0 2.0 4.0 2.0 3.0 2.0 4.0 2.0 3.0 1.0 3.0 2.0 4.0 3.0 3.0 1.0 3.0 1.0 3.0 2.0 -0.48044821018197936 0.03266344168491133 0.055917661485280296 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor molecular_function 22.96192193664894 23.93785496269018 23.147435482608103 23.21037467436421 25.753007465688864 25.01931513802536 19.093355126806518 24.571856993869584 21.68319479371952 23.935737012319695 22.03135405753489 22.80387080510097 21.61712325579627 22.746693461282767 19.206825146752788 24.08837334617241 19.78965337548801 23.156442770814127 21.55426456179216 23.72018192370336 23.18105702196976 23.365520820033197 22.072566476738334 24.768300337190546 21.10719668432281 23.674908279489934 3.0 5.0 36.0 44.0 4.0 20.0 7.0 21.0 11.0 7.0 13.0 8.0 2.0 20.0 4.0 15.0 9.0 16.0 21.0 12.0 18.0 14.0 4.0 10.0 2.0 1.0 3.0 3.0 3.0 2.0 3.0 2.0 6.0 1.0 7.0 6.0 1.0 3.0 2.0 3.0 3.0 2.0 3.0 3.0 4.0 5.0 2.0 2.0 -0.9759330260412398 0.0014961642897455532 0.004424675435076897 GO:0016651 oxidoreductase activity, acting on NAD(P)H molecular_function 25.717852918725978 25.977711721558986 24.84319178299687 25.14369489559498 25.380470116133257 26.25684958188129 25.55930307240307 27.019953316886806 25.26150618501008 25.830238921973137 25.809002713567857 25.140372857590343 25.66849826789261 25.731672905981327 25.51758538077046 26.411031024210054 25.02992310989137 25.96959807569713 26.76948117693903 25.69801313660264 25.832430928796448 25.392454275673323 26.16203877692086 26.228803868824016 25.71726806701477 25.71807193742255 35.0 38.0 30.0 60.0 64.0 65.0 76.0 50.0 82.0 69.0 77.0 40.0 78.0 49.0 58.0 49.0 169.0 74.0 59.0 44.0 87.0 44.0 85.0 65.0 5.0 3.0 3.0 4.0 5.0 4.0 4.0 5.0 5.0 5.0 5.0 4.0 4.0 4.0 5.0 4.0 5.0 4.0 5.0 4.0 5.0 3.0 4.0 5.0 -0.25985880283300844 0.18420928818665294 0.2488021554728819 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor molecular_function 22.20941213082602 19.66073845262984 16.829869221189337 19.74248288278644 21.05297020339475 18.91237894391044 21.249906409268434 16.9643549846097 18.63099805401325 16.884399305410476 21.311733684736645 20.292765342105106 21.954807286503367 18.63008478794837 21.052263951638068 18.115157272896788 19.93837384205259 19.66093363741029 24.75663669233469 20.011011607865182 22.037059782718377 21.341132736782672 22.541330130009182 NA 22.069704284004388 19.90477637953819 1.0 3.0 5.0 3.0 6.0 1.0 5.0 1.0 9.0 8.0 11.0 3.0 7.0 2.0 3.0 4.0 48.0 4.0 9.0 1.0 10.0 NA 9.0 6.0 1.0 1.0 1.0 1.0 2.0 1.0 2.0 1.0 3.0 2.0 3.0 2.0 1.0 2.0 1.0 1.0 3.0 2.0 3.0 NA 2.0 NA 3.0 2.0 2.548673678196181 0.011623418933330592 0.023321586541473597 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors molecular_function 24.422651879485326 24.74700199305645 24.95214150685093 23.854386965527677 25.176061296635137 24.063750743403244 23.685267975615268 25.049501402158786 23.275042617366317 25.74077769001841 23.416244951053237 24.90706334997505 24.153545071081297 23.75428877137149 25.07852224638928 24.3352599495416 24.248935789455363 25.042094974636587 24.275473368997968 24.887055484711862 24.71512489185109 24.20679008872256 24.53065215090489 24.588371290274488 24.14404194419309 25.158316883689537 33.0 18.0 22.0 14.0 32.0 34.0 25.0 47.0 28.0 36.0 29.0 24.0 30.0 25.0 35.0 45.0 40.0 31.0 28.0 22.0 42.0 31.0 31.0 38.0 5.0 1.0 2.0 2.0 3.0 3.0 5.0 3.0 5.0 5.0 3.0 3.0 3.0 3.0 7.0 3.0 5.0 4.0 5.0 3.0 4.0 3.0 5.0 3.0 -0.32435011357112487 0.29869755599497017 0.3712893923124729 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors molecular_function 26.040040998063308 26.595506873808716 25.01795692918931 25.954650605660863 24.070103556796063 26.46078917638071 26.668103123602762 27.645329283275395 25.55802923531313 26.5206339649532 26.706742939735822 25.733274552326325 26.27634181647344 26.74302609849175 25.951804907485585 26.856138734932884 24.92494340972293 26.500123986267447 26.52409366388384 26.56009560251311 25.97157645077024 26.067435683997502 26.23270595900842 26.76687893924425 26.44922270091753 26.3456232774626 42.0 49.0 26.0 67.0 69.0 87.0 78.0 73.0 78.0 84.0 70.0 60.0 82.0 69.0 55.0 61.0 95.0 96.0 45.0 53.0 71.0 58.0 89.0 76.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 4.0 4.0 4.0 3.0 5.0 3.0 3.0 3.0 5.0 5.0 3.0 3.0 4.0 3.0 4.0 3.0 -0.5554658757454085 0.03766692222862868 0.06276144050911694 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor molecular_function 25.064644507055192 25.842171363235067 24.35871346880145 24.99083995968737 23.546739044288262 26.17077390857462 25.28536026395991 26.87750324075956 24.89863068497631 25.6819459588334 25.414562069048113 24.865116030169034 25.089606828962783 25.67456589325079 25.080661072650024 26.293268871261247 24.33079961871084 25.902897214843488 25.651322765998586 25.484130891927126 25.09734947485525 25.178097611077014 25.616866363760362 26.162134158936233 25.183253902917148 25.478973928767942 23.0 28.0 17.0 47.0 39.0 44.0 47.0 41.0 48.0 44.0 44.0 32.0 44.0 38.0 34.0 38.0 57.0 56.0 27.0 32.0 51.0 36.0 46.0 42.0 3.0 2.0 2.0 4.0 5.0 6.0 4.0 2.0 4.0 5.0 5.0 3.0 4.0 4.0 4.0 4.0 4.0 5.0 3.0 2.0 4.0 5.0 5.0 2.0 -0.7775268561798754 0.007911788680711459 0.016907384030013527 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor molecular_function 20.370205337136973 21.774347077328702 19.63493954499624 21.720347024674115 NA 18.586869004725283 20.88246610448547 22.28605901211187 18.36333947117617 20.914121989228967 19.67089898972304 20.876549610731388 18.90935356285953 23.62666287424611 21.84849813758777 22.16874995100954 NA 18.19551781483638 17.604908198731817 21.465801725130707 19.09400618058789 21.194923352667754 19.5790195378953 22.1328705921251 21.866425857092466 21.14390358903287 3.0 6.0 NA 3.0 3.0 11.0 2.0 4.0 5.0 7.0 2.0 14.0 9.0 10.0 NA 1.0 2.0 10.0 2.0 7.0 1.0 5.0 10.0 7.0 2.0 2.0 NA 2.0 2.0 3.0 2.0 1.0 2.0 3.0 1.0 2.0 2.0 3.0 NA 1.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 -1.4041417401917293 0.04791275500844763 0.07795973696289783 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor molecular_function 26.631771667679768 26.550194371790372 25.825823676684593 24.46617019658727 NA 23.38471990028204 26.535948176765604 26.03777424178638 25.99390744983603 27.8589581276185 26.63387519936905 27.318630246299872 26.822320622487826 26.68105381129034 25.81023823664889 25.70372813181488 24.98369874662773 25.316781350290533 27.51652210711709 26.59468924321033 26.832152947642946 25.575057249262905 27.696762752814585 26.925696776061848 26.186497833563628 27.443342918458015 23.0 13.0 NA 13.0 24.0 53.0 47.0 46.0 41.0 45.0 31.0 26.0 35.0 41.0 25.0 39.0 52.0 32.0 38.0 31.0 38.0 39.0 24.0 37.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.08157729588939588 0.6224606558934543 0.6911306926646184 GO:0016692 NADH peroxidase activity molecular_function 25.805804655911242 26.19479871478419 25.502184736409372 17.518851710086615 NA NA 24.94637472798747 25.11921078606009 25.06718968708283 27.598016110076433 24.86139631303468 27.07433064830009 25.90505030872005 26.103782978144302 25.403709745925433 24.68654853441725 24.467661094001908 24.08368630607061 26.344218739973666 26.39264925166963 26.146391526832836 25.064750783715173 27.40259532105204 26.14109548971261 24.950662571508474 27.157662472343322 7.0 1.0 NA NA 8.0 8.0 9.0 10.0 8.0 8.0 8.0 7.0 9.0 7.0 6.0 7.0 7.0 8.0 11.0 11.0 10.0 9.0 7.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.38899405887294947 0.6695085659968565 0.7310119775713709 GO:0016695 oxidoreductase activity, acting on hydrogen as donor molecular_function 23.50806119206131 22.87006514560455 21.072443418478088 NA NA NA 22.104525116191684 21.686841126994075 22.401727940053 23.916566593827966 22.243154417994415 22.9079237746346 23.503003994040174 21.440263762292865 22.243531999245835 20.53491181206916 22.38304574862029 22.566116706296967 25.70202961720121 22.327578000011968 22.425005613427672 19.573355465750765 24.263871195659213 20.42740037150737 23.432679093761053 24.911254604345004 7.0 NA NA NA 9.0 8.0 12.0 19.0 11.0 13.0 18.0 10.0 11.0 3.0 11.0 10.0 32.0 14.0 12.0 3.0 19.0 7.0 20.0 23.0 2.0 NA NA NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.6379960464567596 0.2598752364812036 0.333666970296854 GO:0016722 oxidoreductase activity, oxidizing metal ions molecular_function 24.221305103164948 25.725148917308893 23.344368996574158 23.497815402308078 26.892977001128703 27.67332275075491 20.638515355255198 25.92532577807752 21.633513758155708 25.279025698690713 24.314576358982762 24.292652124913978 21.798321265385624 22.073202813710537 19.771909128315716 26.511193842050094 20.56596438094373 25.33267387476253 23.895716662102252 24.63897040298023 25.40615885343641 26.60637773402289 22.62215597386126 24.218295323655358 20.014805854313927 24.552820584268517 9.0 9.0 21.0 38.0 5.0 19.0 4.0 13.0 5.0 12.0 5.0 8.0 3.0 21.0 2.0 18.0 13.0 13.0 18.0 29.0 8.0 18.0 4.0 14.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 -1.503843814143945 0.009374768459434895 0.01937038251220985 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups molecular_function 26.03389474363027 26.38996671221852 25.50569458272615 24.00703621378822 23.309056378909393 25.396920121185303 25.559891091446953 26.500394987077176 26.582156402391057 27.29585278426757 26.068450127873202 26.90307976944622 26.561039531426662 25.706209937549705 26.374584647906822 26.172655416650137 25.724695542196265 26.600144990948163 26.147900301261593 26.57389928138096 26.07573682095523 25.8120324158674 26.672607855563026 26.406800247480607 25.648679857581854 26.944132822455522 30.0 20.0 18.0 32.0 38.0 56.0 52.0 49.0 57.0 58.0 49.0 36.0 46.0 48.0 42.0 53.0 47.0 63.0 46.0 39.0 54.0 54.0 49.0 40.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.35607196858824963 0.2040238704744366 0.2705863871967023 GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor molecular_function 23.08533979005033 24.78397958897027 22.630353925257783 24.00703621378822 23.309056378909393 25.395264152688352 21.78934126709013 25.05480133145628 21.806200748409317 24.346620531911245 23.61474634388552 24.582413348903593 23.787330687707076 23.92080291659791 21.86318840104505 25.462392843062148 22.65428213051357 25.242497174831968 22.75419355610754 24.67704711127216 23.77876595388718 24.204049064083986 23.8494375481108 25.166413843032217 22.98478339733914 24.159934214033427 15.0 20.0 18.0 31.0 15.0 35.0 13.0 26.0 31.0 38.0 21.0 21.0 16.0 30.0 16.0 34.0 21.0 35.0 26.0 20.0 23.0 35.0 24.0 21.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 -1.6986397989199382 3.225641456243767e-05 0.0005099643033035255 GO:0016740 transferase activity molecular_function 31.850023373041896 31.31770293445427 31.42034018209765 30.547107451338228 31.349026112796306 31.096975618633518 31.60299309534016 31.390172481922693 31.98278833292155 31.38299951958251 32.138506472339685 31.628193027278556 32.14704417255098 31.17593722056758 32.246125840425556 31.40308896170637 31.379531412950925 31.331051214936032 32.16584603828791 31.61774867305903 31.624125641397 31.0534171002598 31.75639381681629 31.47928703751501 31.970856107416612 31.400082595709605 1669.0 1590.0 1645.0 1944.0 1977.0 2567.0 2278.0 2309.0 2533.0 2509.0 2684.0 1977.0 2587.0 2757.0 1865.0 2647.0 2942.0 2905.0 2172.0 1890.0 2378.0 2501.0 2655.0 2376.0 8.0 8.0 8.0 8.0 8.0 8.0 9.0 8.0 8.0 8.0 8.0 8.0 8.0 8.0 8.0 8.0 9.0 8.0 9.0 8.0 8.0 8.0 8.0 8.0 0.5323204385876252 0.00268017172806849 0.006910856026093958 GO:0016741 transferase activity, transferring one-carbon groups molecular_function 28.752760691501113 28.383675062353 28.947402808934914 27.5387475489998 28.786983036959697 27.835068221020922 27.785802686451145 28.32931046263247 28.062655950970182 28.640804640283065 29.054557246379517 29.53076945151822 29.382657402507714 28.342942591726896 28.489296133229036 28.26048819293149 28.147593433927533 28.098012902125785 28.88474900793829 28.67792532656156 29.464627245742587 28.060782422774416 28.54931621573096 27.908492570479908 28.47933121161375 28.2805559943523 217.0 263.0 177.0 302.0 248.0 389.0 288.0 359.0 340.0 372.0 398.0 306.0 286.0 409.0 225.0 398.0 365.0 366.0 303.0 280.0 256.0 413.0 409.0 345.0 3.0 3.0 4.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 0.36908562914811327 0.0734883472918226 0.11239394291690516 GO:0016742 hydroxymethyl-, formyl- and related transferase activity molecular_function 25.703856297125807 24.93814203097873 26.950563412020806 25.10061837337285 25.8653810983431 23.05840436779017 25.090163540679175 24.81738127569356 23.675140162300725 24.772754849031486 25.62384325059857 26.010207720803503 25.866225428390322 24.3391591460533 24.69052790241642 23.71291869054534 25.504589290502423 23.433958089235567 25.982690601234733 26.53190344420489 25.796178163670998 24.632221432530127 25.68916897023826 23.72474035903337 25.56653746055422 24.93267505658645 26.0 20.0 29.0 15.0 30.0 27.0 24.0 36.0 36.0 33.0 46.0 23.0 32.0 14.0 32.0 18.0 45.0 32.0 44.0 26.0 22.0 11.0 48.0 32.0 2.0 3.0 3.0 3.0 4.0 3.0 4.0 4.0 5.0 3.0 5.0 5.0 5.0 3.0 5.0 4.0 6.0 4.0 4.0 4.0 5.0 2.0 5.0 4.0 0.765714266147075 0.03266344168491133 0.055917661485280296 GO:0016743 carboxyl- or carbamoyltransferase activity molecular_function 28.084552705435343 27.40093388544472 28.060705602379745 25.697435180995683 28.085311164005017 26.583653814079327 26.89136398725447 27.338508831261002 27.4911940718348 27.862207009169182 28.396838783311864 29.04199651598218 28.850075248999058 27.271144920369412 27.74026845248457 27.20828180794785 27.61612032660951 27.265034311202307 28.15608304054236 27.144844618641837 29.034253808518 27.280814919695334 27.558771655080733 25.84636352222013 27.73851318116057 27.208495091700808 57.0 30.0 36.0 39.0 65.0 86.0 87.0 72.0 71.0 68.0 79.0 41.0 97.0 66.0 57.0 71.0 80.0 73.0 92.0 74.0 78.0 42.0 77.0 75.0 3.0 1.0 1.0 1.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 0.6836188199906239 0.006656727227605034 0.01478219854101616 GO:0016744 transferase activity, transferring aldehyde or ketonic groups molecular_function 24.998540809305677 24.339215531835784 23.234494270041512 23.63028981142601 23.636854800430488 23.77930971887982 24.762591432758022 23.04592732893857 24.94560921896376 23.44807991981543 25.66698018564169 24.81605870052352 25.61269214030395 24.972229131432872 24.36331915301705 24.83356574710547 24.30503788329909 24.126536817488052 25.059245388378066 24.305239413688213 25.54631435871501 23.581233016083782 25.455634652008943 25.561267589032997 25.313029287045946 23.712663189263694 15.0 14.0 13.0 24.0 22.0 21.0 26.0 18.0 31.0 31.0 26.0 18.0 27.0 29.0 22.0 23.0 21.0 28.0 31.0 17.0 28.0 26.0 32.0 26.0 3.0 2.0 3.0 2.0 4.0 4.0 2.0 4.0 3.0 3.0 4.0 4.0 3.0 4.0 2.0 4.0 3.0 3.0 4.0 3.0 2.0 3.0 3.0 3.0 0.6593252774698932 0.04964722965745621 0.07872902492059129 GO:0016746 transferase activity, transferring acyl groups molecular_function 30.278832325709864 29.05728793160471 29.696115194955922 27.5123326987006 29.700213040543858 29.141391945538654 30.013877674528466 28.990231611638393 30.282931887354174 29.41809274410203 30.334602050473947 29.20260775084084 30.603460187220048 28.14498648423315 30.893379047682252 29.0440452451444 29.83390098752737 29.146085690869022 30.900054280610814 29.58309547761633 29.995825509451237 29.07485018685563 30.04347240080429 29.03526287779189 30.363770469737524 29.3559971353626 388.0 170.0 386.0 397.0 455.0 429.0 549.0 411.0 539.0 460.0 554.0 276.0 661.0 374.0 430.0 393.0 673.0 571.0 536.0 333.0 575.0 363.0 541.0 426.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 1.2215443941051554 3.225641456243767e-05 0.0005099643033035255 GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups molecular_function 30.23837588015941 28.97678043364702 29.655558699865498 27.40570473882121 29.6416176977955 29.03265772314884 29.96373531697969 28.951079795078783 30.270825416024927 29.379568044582825 30.29977862208785 29.115311944443725 30.56791022561003 28.01512935280721 30.85670670223533 28.94116890145475 29.788975096458305 29.05308245984191 30.86055767583361 29.531507273564586 29.950401033623905 29.04191157751925 29.97829230857168 28.87452394650257 30.3236311356354 29.27393623511805 350.0 131.0 334.0 314.0 424.0 378.0 516.0 363.0 500.0 402.0 508.0 229.0 621.0 296.0 406.0 333.0 646.0 516.0 491.0 281.0 527.0 302.0 498.0 365.0 10.0 9.0 12.0 12.0 13.0 11.0 13.0 11.0 13.0 13.0 13.0 12.0 13.0 11.0 14.0 12.0 13.0 10.0 13.0 12.0 14.0 13.0 13.0 12.0 1.2615954465123913 3.225641456243767e-05 0.0005099643033035255 GO:0016748 succinyltransferase activity molecular_function 22.99912328110577 19.970393704579585 20.84882963098996 17.627455475523238 19.893886909243754 19.347148015819442 22.662299792917576 19.826122588363894 20.56523689909532 16.14374738182182 24.031769279587817 22.496608817032307 24.124972779961855 18.641362351839952 20.16777627105026 NA 22.514997896958604 17.189164788302094 23.50963198940107 18.968316324817696 23.8821473597542 NA 23.59033469564309 16.700048970805273 22.71786433767437 20.316764691617816 4.0 1.0 2.0 2.0 7.0 6.0 6.0 1.0 10.0 10.0 13.0 3.0 4.0 NA 9.0 1.0 17.0 4.0 17.0 NA 11.0 1.0 11.0 5.0 1.0 1.0 1.0 1.0 2.0 1.0 2.0 1.0 3.0 3.0 3.0 1.0 2.0 NA 3.0 1.0 2.0 2.0 2.0 NA 2.0 1.0 3.0 2.0 3.0287295765261852 0.00036993149163163074 0.0014703009603703032 GO:0016755 transferase activity, transferring amino-acyl groups molecular_function 22.63894890766616 21.43181484879468 21.237064446835927 21.984004341998553 20.63417911963743 17.409432010814573 23.193264587608965 19.090375070108145 19.37086426268017 20.59255416406005 21.96808246520824 22.045112143503083 21.998235294858365 22.28074706869488 25.063256936802386 21.524963738169703 23.183248394847013 21.043448973996416 NA 22.1072266638802 20.549707337895878 21.03568513652959 19.812572469301337 21.182585565666773 21.033239381785194 21.871180536048 8.0 10.0 4.0 1.0 7.0 3.0 1.0 6.0 10.0 8.0 8.0 6.0 5.0 10.0 6.0 8.0 NA 11.0 6.0 7.0 1.0 6.0 5.0 10.0 2.0 1.0 1.0 NA 2.0 NA 1.0 NA 2.0 2.0 2.0 1.0 2.0 1.0 2.0 1.0 NA 1.0 2.0 1.0 1.0 1.0 1.0 2.0 1.2071340588714783 0.758288758433211 0.804030901040482 GO:0016757 transferase activity, transferring glycosyl groups molecular_function 26.426127580765662 27.07258068665884 26.511061334294297 26.782027163073767 27.00794469525106 26.814346759548467 25.84645197070199 26.99495045121407 25.90041988748881 26.993146743791822 26.52948672833835 27.12800110651732 26.706690350074386 27.32038036725116 26.34462093048291 27.44769514987464 25.65808663195235 26.87185367369905 26.9090643535352 27.05180996187661 26.3054949457286 26.546807843358106 26.2634607390486 27.854792700484772 26.49229004846003 26.470031797382674 106.0 169.0 129.0 192.0 117.0 197.0 121.0 181.0 143.0 184.0 180.0 168.0 152.0 278.0 111.0 228.0 198.0 197.0 146.0 150.0 141.0 240.0 176.0 154.0 3.0 5.0 5.0 4.0 4.0 5.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 3.0 5.0 4.0 4.0 4.0 5.0 4.0 4.0 -0.6464531058931762 0.0014961642897455532 0.004424675435076897 GO:0016758 transferase activity, transferring hexosyl groups molecular_function 24.432890713636755 25.40279326577645 24.775163791702266 24.996948982079026 25.723309920581013 24.617337738460087 23.43252651591701 25.17655737825871 23.3993182780406 25.85577756782323 24.027812118424702 25.37993528334228 24.58071932017655 24.942426020894708 25.202391243510146 26.21692458002992 23.247158614696712 25.650234059241065 23.71692185493579 25.26261431754273 24.351653847649107 24.768710611015862 24.01458676380949 26.04999774773971 24.415707081386532 24.81854593278377 43.0 74.0 46.0 73.0 34.0 73.0 33.0 77.0 47.0 73.0 65.0 64.0 63.0 136.0 38.0 104.0 59.0 57.0 54.0 61.0 35.0 98.0 64.0 57.0 11.0 13.0 12.0 11.0 8.0 14.0 7.0 14.0 11.0 12.0 12.0 14.0 8.0 13.0 9.0 15.0 12.0 14.0 11.0 13.0 6.0 13.0 10.0 14.0 -0.9699025521396933 0.0014961642897455532 0.004424675435076897 GO:0016763 transferase activity, transferring pentosyl groups molecular_function 25.792423815805826 26.30077207351016 25.563521431264434 26.09478917187674 26.06487378643541 26.23579583108283 25.39478619829472 26.242865976697153 25.16685414829557 25.89125971112386 26.02696992556739 26.421166627658 26.036739087388806 26.835015477941017 25.30317183510241 26.233964022369264 25.237809679729324 25.71174640261529 26.682433626469955 26.415421494061984 25.655475102919432 25.79861322051129 25.69685680064587 27.197288208918142 25.901798724457283 25.697972654634682 44.0 66.0 58.0 71.0 60.0 87.0 58.0 79.0 68.0 77.0 84.0 74.0 68.0 81.0 53.0 75.0 113.0 107.0 64.0 51.0 79.0 84.0 71.0 69.0 9.0 7.0 8.0 11.0 10.0 9.0 8.0 9.0 11.0 10.0 9.0 10.0 9.0 11.0 7.0 9.0 12.0 10.0 9.0 7.0 9.0 8.0 10.0 11.0 -0.5083482577043341 0.007911788680711459 0.016907384030013527 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups molecular_function 25.659336288736643 25.30256453580821 24.750747105521306 24.070369492453064 21.79540821707553 22.453529752103872 25.44639221800809 25.51769004451322 26.12662878347883 25.437628189109702 25.701050035171427 24.84243192989429 26.371461449082645 24.552367639753925 25.972304648084865 25.241487702070106 25.3203038557515 25.996255116167045 25.059224564657736 25.728202558315946 25.409125563523894 24.690951375556768 26.77048411416563 25.3900037274428 25.32343773149671 26.452523655608612 27.0 19.0 11.0 22.0 60.0 65.0 67.0 63.0 65.0 66.0 73.0 54.0 59.0 70.0 55.0 80.0 69.0 73.0 39.0 38.0 67.0 70.0 73.0 59.0 10.0 9.0 4.0 9.0 9.0 11.0 12.0 9.0 14.0 14.0 14.0 12.0 11.0 11.0 12.0 13.0 14.0 13.0 10.0 7.0 12.0 10.0 14.0 10.0 0.35677175292843444 0.3263484733220724 0.4012639356708831 GO:0016772 transferase activity, transferring phosphorus-containing groups molecular_function 30.009146618214288 30.04045976966896 29.89001415206233 29.44851047516461 29.730020796699254 29.89649512659411 29.84011019037817 30.300925046343497 29.98901866742477 30.043836812322002 30.32420253418593 30.251686652180748 30.17114903572465 29.965367875722023 30.30351307790259 30.155165557904105 29.355603396313228 30.123192021329107 30.516914090229825 30.10577845967529 29.83305800440481 29.664938498892933 29.73847150996236 30.27820046189311 30.035940193671646 30.020557546485 692.0 652.0 682.0 699.0 765.0 1039.0 833.0 912.0 964.0 948.0 980.0 757.0 972.0 992.0 726.0 1016.0 1173.0 1110.0 775.0 737.0 865.0 941.0 970.0 986.0 9.0 8.0 9.0 8.0 9.0 9.0 9.0 8.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 8.0 9.0 9.0 9.0 9.0 -0.03131315145467184 0.6441672226837103 0.7073013587238495 GO:0016773 phosphotransferase activity, alcohol group as acceptor molecular_function 27.97785939742156 28.247995947448867 28.363222555374204 27.894412703507328 28.40444872051145 27.88402593062772 27.239898833454326 28.813216798090227 27.66378989948597 28.50425262305653 27.929651650096684 28.686123098915953 27.79148778206428 28.115642881751967 28.139814312202002 28.091710054498872 26.7206905424718 28.297409226876265 28.87736230753603 28.08369060497709 28.426294805038534 27.818855905097088 27.121997830803657 28.23698628216249 27.61971734078381 28.15800117351684 193.0 174.0 235.0 184.0 163.0 259.0 164.0 232.0 219.0 258.0 248.0 189.0 234.0 254.0 157.0 240.0 283.0 255.0 219.0 209.0 186.0 223.0 228.0 260.0 15.0 15.0 14.0 14.0 16.0 19.0 16.0 14.0 18.0 19.0 23.0 20.0 18.0 19.0 18.0 20.0 16.0 18.0 17.0 13.0 15.0 17.0 18.0 17.0 -0.2701365500273063 0.16585666034291002 0.2267131567447445 GO:0016774 phosphotransferase activity, carboxyl group as acceptor molecular_function 27.092514102797665 25.287394943115586 26.12932983232839 22.49821790917889 25.39641334328364 24.020130376247586 26.917971193061927 25.68703932414493 27.60562340018875 25.98675929385756 27.70102009335793 25.688047137327708 27.276659429148086 24.630509216668898 27.764302537586907 24.642072693672837 26.3631690467824 25.42174533839579 27.389255575652356 26.0757209046672 25.45393345781509 24.95838741037088 27.425078847894696 24.639410062439772 27.354887064982773 26.004859366092585 34.0 11.0 15.0 16.0 65.0 64.0 64.0 41.0 60.0 43.0 56.0 25.0 60.0 37.0 53.0 39.0 101.0 80.0 46.0 23.0 74.0 37.0 69.0 46.0 4.0 4.0 3.0 4.0 5.0 5.0 4.0 4.0 4.0 4.0 4.0 3.0 5.0 4.0 5.0 4.0 6.0 6.0 5.0 4.0 5.0 5.0 4.0 5.0 1.8051191596820786 0.00042856814449695465 0.0016457016748683058 GO:0016775 phosphotransferase activity, nitrogenous group as acceptor molecular_function 25.215986634037357 26.81708973184868 26.092193246598 26.121658091832185 25.832480806113672 26.995737751436682 24.140038506739522 26.723488519944983 23.57393697552569 26.2303354464202 24.502344115691226 26.68013219666229 25.34918297832159 26.84752008667712 26.35935610674777 27.240456091570806 24.4096936286549 26.976142169677548 25.502696850582012 26.849742860804806 25.26561313820735 26.555016131396695 23.55533325875902 27.425067047556762 24.853998889199843 26.6299966551442 26.0 33.0 41.0 48.0 27.0 57.0 21.0 56.0 33.0 37.0 32.0 35.0 36.0 48.0 23.0 54.0 53.0 49.0 32.0 35.0 29.0 48.0 33.0 51.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 -1.6011030978113219 5.312128159411724e-05 0.0005099643033035255 GO:0016776 phosphotransferase activity, phosphate group as acceptor molecular_function 25.76406660757469 25.27030599161209 24.21875463361624 24.70334423210064 24.334125572471088 24.064747687683678 26.597685121144572 25.71102433918303 25.794931250889 26.059545461118432 26.34960179101693 25.590947484086012 26.62063097454873 24.8907524793072 24.989058075403232 24.6806744351801 25.706206732519732 25.272294943538842 26.04797678501643 25.5874783130296 25.05040444489636 24.45423010527865 25.48667128270493 24.71911312278676 25.725658217411734 25.97175609607769 38.0 21.0 24.0 16.0 46.0 46.0 41.0 49.0 40.0 42.0 57.0 33.0 44.0 30.0 40.0 42.0 62.0 53.0 46.0 31.0 55.0 30.0 51.0 49.0 2.0 1.0 2.0 3.0 1.0 3.0 2.0 2.0 3.0 2.0 2.0 3.0 1.0 2.0 2.0 1.0 4.0 2.0 2.0 2.0 3.0 1.0 2.0 2.0 0.4937606159626 0.14891467317876572 0.20512749682902828 GO:0016778 diphosphotransferase activity molecular_function 21.573424701592987 21.52375967112169 21.15693063895068 19.77817031615431 20.268692068527635 17.250366345302957 21.034200433431234 19.79137335846011 21.038402488470965 22.191350587464925 20.204622730414254 22.516101239816667 21.727744573815727 22.296668820560388 21.125146099940885 19.369203859126387 20.669148500121906 18.79270556696185 23.38996327945927 21.773074058504253 21.036759234005068 22.06084208080492 22.272219636478162 21.33455157070745 21.365002454766586 22.64185330895256 9.0 4.0 4.0 1.0 5.0 4.0 7.0 4.0 4.0 7.0 8.0 7.0 5.0 4.0 4.0 2.0 2.0 7.0 4.0 4.0 7.0 5.0 6.0 5.0 2.0 2.0 2.0 1.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 1.0 3.0 2.0 2.0 3.0 2.0 3.0 2.0 0.04966503047129578 0.9539596927720386 0.9577970205788449 GO:0016779 nucleotidyltransferase activity molecular_function 26.74855337599711 26.94059128532999 27.130044779814273 26.44537448976457 26.346173774451863 27.376628739702788 26.679282188839174 26.60701418902674 26.610719677712346 26.447312470253845 26.96785627841446 26.893660137042485 26.949151740216895 26.72947205462481 26.53304130261495 27.303414027759136 26.510649176099022 27.099508535521487 26.191058230130828 27.086114373605252 26.860077397020532 26.641019585083793 26.694539712670498 27.576943588783674 27.163268662472486 26.47946463124045 99.0 115.0 75.0 123.0 105.0 125.0 158.0 139.0 158.0 135.0 138.0 116.0 148.0 164.0 117.0 170.0 152.0 172.0 91.0 111.0 121.0 165.0 159.0 131.0 10.0 10.0 8.0 10.0 9.0 10.0 7.0 10.0 9.0 10.0 9.0 10.0 7.0 10.0 9.0 9.0 9.0 10.0 8.0 10.0 7.0 9.0 9.0 10.0 -0.1920379093328819 0.4189234409463829 0.5022252202700153 GO:0016780 phosphotransferase activity, for other substituted phosphate groups molecular_function 19.65054742124372 20.341860496144786 19.328749523044984 19.42642024652045 18.94498475203671 21.52720695552728 18.201309988293666 18.040170105118026 20.41316950764316 NA 18.62965573126247 19.736232659338967 19.785383538923828 20.249710988123397 18.907504575988867 20.613736981286173 21.063277631638613 20.14108926145804 19.91584018219622 19.893386361287945 17.711260770790773 20.151148711883145 17.766116678041538 21.40441749842563 20.606454941227547 19.657820506802487 2.0 4.0 1.0 6.0 1.0 2.0 2.0 NA 2.0 3.0 2.0 8.0 1.0 10.0 3.0 9.0 7.0 5.0 4.0 2.0 3.0 6.0 3.0 4.0 2.0 3.0 1.0 4.0 1.0 2.0 1.0 NA 1.0 3.0 1.0 4.0 NA 5.0 2.0 1.0 1.0 4.0 4.0 2.0 2.0 4.0 1.0 2.0 -0.6913130749010676 0.09656589443461913 0.14111737266323732 GO:0016781 phosphotransferase activity, paired acceptors molecular_function 24.8188101258041 20.766950241452847 18.97226693843477 NA 14.416885645034807 NA 25.653729208454088 21.39206014041833 24.889172503966265 21.40817957040698 26.26725382757261 21.554489787283238 24.234916046376124 17.9248319364292 24.66790617427717 19.55955449219862 25.25417945474997 20.344610542191152 22.665829928475908 21.808203193033037 20.533481773819165 NA 24.422947137306448 18.10978702071604 26.1190742143962 20.115458511763197 3.0 NA 1.0 NA 24.0 3.0 29.0 3.0 38.0 5.0 24.0 1.0 30.0 2.0 27.0 3.0 17.0 11.0 5.0 NA 27.0 2.0 19.0 3.0 2.0 NA 1.0 NA 3.0 1.0 2.0 1.0 3.0 2.0 3.0 1.0 2.0 1.0 2.0 1.0 3.0 3.0 3.0 NA 3.0 1.0 2.0 1.0 4.051859884351252 0.015680223059080796 0.030292443309183948 GO:0016782 transferase activity, transferring sulfur-containing groups molecular_function 28.409793250794174 24.77169656112886 21.555369598148552 23.97874708911943 21.80524297316526 24.77190286453897 28.72243107325128 24.40718950391978 29.58402041928558 23.72806570678382 29.32828171373121 23.765146311239747 28.54544505347777 24.35394744590413 28.860699927163505 24.38650054821754 28.57472844516953 24.085914881632032 26.98801696106852 27.011573942344594 23.49994589391677 23.608816406014448 28.087881221563965 24.787281617220373 29.257085957557322 23.241098152653322 12.0 27.0 11.0 37.0 61.0 41.0 108.0 28.0 99.0 37.0 78.0 35.0 108.0 39.0 58.0 33.0 83.0 102.0 31.0 26.0 92.0 43.0 80.0 27.0 2.0 1.0 3.0 2.0 3.0 1.0 3.0 2.0 3.0 3.0 3.0 2.0 2.0 1.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 2.0 1.0 3.638096689665314 0.03766692222862868 0.06276144050911694 GO:0016783 sulfurtransferase activity molecular_function 21.77273516597249 24.203557115081573 20.66958285806486 23.97874708911943 21.11948158050824 24.760449813483934 19.821707211056193 24.40718950391978 22.163155805105838 23.717974527291304 22.231921310215697 23.738993495850693 22.13171789125121 24.337069104243888 21.87688275768484 24.38650054821754 22.065714607813128 24.084808877346443 21.465123685351212 24.553455168132967 21.502024301821194 23.60678286204391 22.1844843054764 24.76981148100729 22.26304675026217 23.241098152653322 7.0 27.0 8.0 36.0 4.0 41.0 9.0 27.0 11.0 32.0 10.0 33.0 12.0 39.0 5.0 32.0 13.0 40.0 8.0 25.0 14.0 39.0 7.0 27.0 2.0 2.0 2.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 1.0 3.0 5.0 2.0 2.0 2.0 3.0 2.0 1.0 2.0 -2.430821949109081 3.225641456243767e-05 0.0005099643033035255 GO:0016787 hydrolase activity molecular_function 31.57179097518648 31.929548709928866 31.52462141278746 31.25420434166265 31.151390573855647 31.70947163484004 31.10058682068349 31.87572983633412 31.615156418143965 31.887948913682827 31.66217451399851 32.1102730721491 31.62754773751616 31.70658640836141 31.64004228940775 32.139396830183664 31.06909075713521 32.062534939709565 32.1028432839832 32.278480624842324 31.910206913062854 31.78982515805087 31.577930652804564 32.08168765829474 31.514654734056855 31.992260341452397 2100.0 2263.0 1776.0 2665.0 1653.0 3004.0 1960.0 2780.0 2184.0 3007.0 2349.0 2725.0 2412.0 3396.0 1641.0 3249.0 2662.0 3100.0 1885.0 2548.0 1933.0 3173.0 2237.0 3006.0 10.0 9.0 9.0 10.0 9.0 11.0 9.0 10.0 9.0 12.0 11.0 11.0 9.0 11.0 9.0 11.0 8.0 11.0 9.0 9.0 10.0 11.0 10.0 11.0 -0.3577577347423855 0.003892417122778628 0.009377869824763952 GO:0016788 hydrolase activity, acting on ester bonds molecular_function 28.328346552771386 28.938175921356567 28.09830153443109 28.27846054321265 27.545367295836268 28.516722983247607 27.766178862644296 28.59867768767437 28.500913915989212 28.809367561636748 28.172311073103298 28.75161635568201 28.40720635233037 28.938838676804394 28.18257334749847 29.06895176973381 27.482109026749892 28.524549104479018 29.540641818042296 30.30266629802084 28.8554525083353 28.37752724992198 27.983412735526194 28.995754734840197 28.011174156618253 28.78148302835009 350.0 447.0 340.0 461.0 306.0 528.0 287.0 497.0 401.0 540.0 495.0 526.0 380.0 641.0 256.0 604.0 450.0 517.0 391.0 451.0 334.0 633.0 449.0 530.0 4.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 5.0 5.0 6.0 6.0 4.0 4.0 5.0 4.0 6.0 4.0 5.0 5.0 6.0 4.0 6.0 4.0 -0.6098293685851814 0.004669131805023211 0.010994483948432015 GO:0016790 thiolester hydrolase activity molecular_function 24.9974687626091 24.84716516617209 24.641706786912174 19.894812185147746 19.64243787523112 17.825957912136904 25.147023673821288 24.479093047046657 24.57802138315931 26.18979951371569 24.74448804571405 25.538271783321466 25.43112612134956 24.16644888008157 24.406105512774644 22.89157444822108 23.58381619568661 24.314729478251184 25.91393335444075 25.20270161381433 25.42805475898225 23.768805321364322 25.586691796204352 24.18088895767961 25.4501495189613 26.46930240864164 17.0 5.0 5.0 2.0 8.0 14.0 11.0 19.0 10.0 14.0 15.0 11.0 13.0 14.0 7.0 11.0 11.0 13.0 15.0 11.0 10.0 16.0 12.0 11.0 3.0 1.0 2.0 1.0 1.0 2.0 2.0 2.0 1.0 3.0 2.0 1.0 2.0 2.0 2.0 3.0 1.0 1.0 2.0 1.0 1.0 3.0 2.0 1.0 0.1503035964370092 0.29869755599497017 0.3712893923124729 GO:0016791 phosphatase activity molecular_function 23.02925166842556 24.958814887938146 22.585776355559297 23.858492020555662 23.728696667848602 25.98107943943277 21.70260531890972 25.082138053588377 20.83856559015269 24.14317752270208 23.484534295244064 24.41931738819073 23.481408135155053 23.86626643363865 22.89272679028837 26.15910995617239 21.897373962665487 24.18047252983524 23.966674078696844 24.68290362903692 22.901934544654154 25.81259323402503 22.90809453493528 23.768112723082773 23.25300490096056 24.51657942282586 21.0 25.0 20.0 28.0 6.0 35.0 9.0 28.0 17.0 35.0 19.0 29.0 15.0 51.0 8.0 38.0 34.0 30.0 19.0 33.0 11.0 24.0 19.0 34.0 4.0 7.0 4.0 6.0 2.0 7.0 2.0 7.0 4.0 10.0 5.0 6.0 4.0 7.0 4.0 9.0 7.0 5.0 5.0 6.0 4.0 7.0 5.0 6.0 -1.9295632195125876 6.784570247173055e-05 0.0005498145239267514 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters molecular_function 22.97268912234688 25.014193462853427 24.25934433215691 24.679430869589602 24.009336682241145 24.68460952942273 21.387660318439835 25.039797533391557 21.062276211098943 24.594402870822396 21.838531418621788 25.13957479870888 22.912014488376194 25.2851847923458 23.52658847502477 25.43101834436976 21.576679690137173 25.077123649472213 23.436356496006265 25.002059137394987 23.387960705000488 24.911995718797584 21.03639963035939 25.399711551764284 22.401943980543923 24.57844561984593 29.0 43.0 29.0 40.0 16.0 47.0 10.0 45.0 21.0 41.0 27.0 41.0 26.0 52.0 13.0 48.0 34.0 38.0 26.0 42.0 12.0 50.0 25.0 37.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -2.041504340506549 3.225641456243767e-05 0.0005099643033035255 GO:0016798 hydrolase activity, acting on glycosyl bonds molecular_function 24.85560730205895 25.853455320008106 26.19196554236976 24.6721401352075 24.83876906742993 25.883247992913407 22.40612971796564 25.44419778094285 23.515494707556144 24.61811578011711 24.409378901891237 26.52715480371955 23.323346053416905 24.95602561097993 25.83574108817757 26.36405330834485 23.11152346702589 26.90307278565184 25.61120796467041 24.30455513203989 25.609541234146146 25.91754248194001 24.125373723894313 26.07788309538603 24.069767128608106 26.090165193724236 162.0 123.0 85.0 107.0 22.0 156.0 14.0 110.0 48.0 186.0 41.0 126.0 144.0 251.0 42.0 204.0 120.0 85.0 62.0 116.0 44.0 145.0 56.0 76.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.9978480179491562 0.011074437676156606 0.022291771322328135 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds molecular_function 20.50453718846796 20.072941380409567 19.999367811476468 19.432485211213613 19.595204441964515 19.88322869305797 19.16816719213268 20.37135892511564 20.947737286083182 18.100001104497174 20.40592986090428 20.91599371649048 20.199060154825254 20.72565129296913 21.533753779529384 20.99553276524172 16.75393150850488 20.622426520464295 21.928857827716584 19.927064390628484 18.16289456788961 19.994541119005554 18.47733948214997 18.339519555951675 21.520706967490508 17.019645750226914 3.0 2.0 2.0 4.0 6.0 2.0 7.0 2.0 5.0 3.0 7.0 4.0 8.0 3.0 1.0 3.0 14.0 4.0 1.0 3.0 3.0 3.0 10.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 NA 2.0 6.0 3.0 1.0 2.0 2.0 2.0 2.0 2.0 0.43159580805839326 0.6033317722918665 0.6716842567531217 GO:0016805 dipeptidase activity molecular_function 24.24120128556477 24.989624419816288 24.49931593304673 25.033242569680624 24.566762518495782 25.00964106952698 23.90746416160293 25.0031851528404 22.178375470031323 25.102833827564286 24.471893014930444 25.11701167527028 25.073185794239183 24.69408741277737 24.29052027320404 24.40248579626925 23.96214483144051 24.604663364233406 25.121452837579927 25.6763861624979 22.45742928750211 24.682003131761466 22.12597027874591 24.997816081838824 24.667459898827442 25.13024606772623 20.0 23.0 48.0 44.0 13.0 35.0 12.0 34.0 18.0 36.0 31.0 20.0 16.0 32.0 11.0 34.0 41.0 39.0 20.0 21.0 15.0 35.0 29.0 34.0 1.0 1.0 3.0 3.0 2.0 2.0 2.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 -0.7484231342515173 0.004669131805023211 0.010994483948432015 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds molecular_function 26.29645570539888 25.460004386141247 26.29468676318189 24.330492638905678 24.460939360247412 24.833630939088717 25.376957960868076 25.73425808886939 26.028721898142845 25.89034238498873 26.774779280436807 26.62688412145379 27.19312276619083 25.795630542514743 25.921655952762087 24.92364602012402 25.50163635970405 24.701003451147713 26.359559519848204 25.87655768017399 26.760037380675 24.82799981382637 26.868485421291272 24.457982593250232 26.060157318496056 25.5593670565618 53.0 44.0 42.0 51.0 69.0 94.0 84.0 98.0 89.0 98.0 107.0 73.0 76.0 66.0 67.0 65.0 100.0 95.0 59.0 58.0 88.0 67.0 95.0 83.0 5.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 0.8364513192576339 0.009374768459434895 0.01937038251220985 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides molecular_function 25.54808871977601 24.663096627732248 25.711863276766987 23.536799009125186 23.152148051383747 24.42576923400276 24.23339892454009 25.036976004795523 25.289451014149225 24.900332985325715 26.112479643733764 25.992353580343515 26.14747869528779 24.81886722192341 25.36515693280732 23.83099299114789 24.603953963476663 24.36148936409378 25.66114366352087 24.709636091773266 26.368175234232744 24.21337087801071 26.245872096920532 23.78419346997871 24.782881948409205 24.52778950209705 25.0 26.0 21.0 27.0 24.0 61.0 35.0 37.0 32.0 38.0 29.0 33.0 31.0 39.0 25.0 43.0 47.0 39.0 18.0 33.0 21.0 33.0 39.0 30.0 8.0 8.0 7.0 5.0 8.0 10.0 10.0 11.0 8.0 8.0 9.0 9.0 9.0 10.0 7.0 13.0 12.0 9.0 7.0 8.0 7.0 9.0 11.0 11.0 0.8849920920437633 0.024343383653741054 0.04309296851045225 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides molecular_function 22.58564028597205 22.189218662901038 23.48174546206084 21.943758556005967 23.31556257238429 21.019025546882023 21.449007536887915 21.51645935862939 21.018673738763987 22.701381803813877 23.10358070134389 23.15955410853354 23.419156768339953 21.314687531068856 20.11852799021309 21.167174412099726 22.44079439026269 20.13890657070641 22.17988404771071 22.93036713890686 22.84014333730745 20.902733109920145 21.150671727474887 21.272231752985753 22.68486253130268 23.679251223196783 10.0 6.0 8.0 8.0 7.0 6.0 4.0 15.0 10.0 17.0 15.0 9.0 7.0 5.0 11.0 5.0 10.0 10.0 13.0 6.0 7.0 7.0 14.0 20.0 4.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 4.0 2.0 4.0 2.0 4.0 3.0 4.0 3.0 0.3964216230710136 0.3864762307712327 0.4687291895068012 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines molecular_function 22.691310847441372 22.683566138209468 22.83898573481673 22.075573221987295 21.09682361393378 22.32062161339445 22.793021919656468 22.92899349354066 21.89097412925122 22.752785184285198 23.51494085834505 23.66142317307631 23.56707209770841 22.38113496489524 22.042017915422207 23.03204436972281 22.640845358565755 21.92553030379827 22.028874216846585 23.372170140800595 22.650151365729176 22.06885721822277 22.203913853286203 21.962147758797173 23.16512375802412 22.389317271862737 7.0 10.0 8.0 16.0 19.0 20.0 12.0 32.0 20.0 29.0 26.0 16.0 17.0 18.0 15.0 13.0 16.0 23.0 16.0 16.0 18.0 16.0 21.0 15.0 4.0 6.0 3.0 2.0 3.0 4.0 3.0 5.0 2.0 6.0 4.0 4.0 4.0 4.0 2.0 3.0 6.0 6.0 4.0 4.0 3.0 4.0 2.0 4.0 0.007744709231904068 0.9080725552559752 0.9266349541778063 GO:0016829 lyase activity molecular_function 30.599125338010047 29.73199890146244 29.38581571254021 28.141307824958357 29.640145959421865 28.995451537567078 30.35329354780632 30.20526992756276 30.702345884131788 30.31349699186303 30.988727125439606 29.92558001384496 30.805170472013426 28.80005123007733 31.07396583586441 29.83288059721607 30.417228536319037 30.28205375935051 31.070987052686736 29.824375860594035 30.65847954065848 29.39988772938885 30.632385673448855 28.96464244123905 30.5247032798733 30.346329245746503 367.0 217.0 338.0 270.0 523.0 454.0 624.0 514.0 587.0 470.0 608.0 331.0 626.0 396.0 473.0 451.0 717.0 589.0 534.0 355.0 637.0 320.0 565.0 465.0 5.0 4.0 5.0 5.0 6.0 6.0 5.0 6.0 6.0 7.0 7.0 6.0 5.0 7.0 6.0 6.0 6.0 7.0 6.0 6.0 6.0 6.0 6.0 6.0 0.8671264365476077 0.0009986863791802587 0.0031633517797384847 GO:0016830 carbon-carbon lyase activity molecular_function 29.36411974010376 28.616329886697674 28.33233766542017 27.553655827000213 28.518399287428927 28.03462922295012 28.96221381009705 28.988998828124803 29.134589747679428 28.634241580811658 29.970473868583497 28.67405058482224 29.546744325231558 27.871893642687372 29.806665859567453 29.078379488982296 29.21006329990028 29.405320577949986 29.66788445655973 28.50230713622864 29.62450460651958 28.335082888778192 29.148588154819368 28.117353441916183 29.54837268720023 29.04743065755456 148.0 100.0 157.0 97.0 196.0 164.0 260.0 177.0 232.0 158.0 219.0 121.0 233.0 142.0 182.0 151.0 251.0 195.0 221.0 132.0 238.0 93.0 195.0 187.0 4.0 3.0 3.0 3.0 6.0 4.0 6.0 4.0 6.0 5.0 6.0 4.0 6.0 3.0 6.0 3.0 6.0 6.0 5.0 4.0 6.0 3.0 6.0 5.0 0.7477898534060863 0.0032349119169146935 0.007931571851295751 GO:0016831 carboxy-lyase activity molecular_function 27.9778494903394 26.43171627297625 26.34677209407291 21.82546125368383 23.36086488592816 22.68984417664526 27.35874191024354 27.224538207594108 28.132047550215805 27.492162890606554 28.46361082331344 26.75899412758726 28.38465541304749 24.613790498098307 27.75848365000032 25.19550758523921 27.622697296888127 27.34566311379264 29.23318941932867 25.9759342464006 28.652343752051753 25.645630882123523 27.63704247207353 25.014306453391427 27.52944292559952 27.77415447695609 50.0 13.0 30.0 9.0 69.0 40.0 108.0 61.0 89.0 50.0 84.0 34.0 73.0 33.0 74.0 40.0 98.0 65.0 101.0 31.0 99.0 24.0 54.0 56.0 9.0 4.0 6.0 3.0 9.0 8.0 10.0 9.0 10.0 10.0 10.0 7.0 9.0 8.0 9.0 8.0 11.0 11.0 11.0 6.0 11.0 7.0 8.0 10.0 1.546133217363149 0.0032349119169146935 0.007931571851295751 GO:0016832 aldehyde-lyase activity molecular_function 27.29347977434536 28.200337547689514 27.726681373812713 27.507901992215466 28.251031818810297 27.996322474228144 26.499163901404142 28.47550823209362 26.12100099859024 27.7023350746217 27.23142103653841 28.085493549100608 26.887681090124264 27.68141661226136 28.46861982182939 28.96293656953627 26.464556130613182 28.99557953674516 27.47048419861139 28.10453502658061 27.04004866989338 28.08309008150055 26.39637864627481 27.90602573886293 26.665935652845626 27.996753552483696 72.0 82.0 101.0 85.0 62.0 109.0 73.0 95.0 64.0 73.0 61.0 68.0 76.0 94.0 47.0 93.0 100.0 91.0 80.0 91.0 59.0 47.0 77.0 104.0 7.0 7.0 7.0 5.0 10.0 7.0 9.0 7.0 9.0 9.0 7.0 7.0 6.0 7.0 6.0 6.0 8.0 10.0 7.0 6.0 8.0 6.0 11.0 7.0 -0.9068577733441536 0.0032349119169146935 0.007931571851295751 GO:0016833 oxo-acid-lyase activity molecular_function 25.751063240550426 22.641874617215123 24.443808084552806 21.214565635055568 25.69368409134869 18.74309213420968 25.45463281584288 21.348605633766912 26.32298208152741 23.154713190084987 25.97028560398984 23.863759217217893 26.286044035175014 22.14932171566618 25.560562299846936 22.30088144793462 26.22540332293965 22.320916121790546 24.31451761666615 23.801564441994877 23.99448070181343 20.743413353036352 25.207440929354323 22.464449860758627 26.824253141335905 23.41277671120475 22.0 5.0 26.0 3.0 37.0 14.0 50.0 19.0 37.0 26.0 52.0 18.0 50.0 15.0 41.0 18.0 40.0 30.0 21.0 9.0 56.0 22.0 40.0 20.0 5.0 2.0 3.0 3.0 5.0 4.0 5.0 3.0 6.0 6.0 5.0 4.0 9.0 7.0 6.0 4.0 6.0 6.0 5.0 3.0 6.0 4.0 6.0 5.0 3.109188623335303 3.225641456243767e-05 0.0005099643033035255 GO:0016835 carbon-oxygen lyase activity molecular_function 27.888335380245696 28.06994348642682 27.29436412235046 23.71764979163541 24.31630888052361 24.795073687692962 27.18354415638029 28.85238648606505 27.70326768048201 29.262308813292705 27.16645710654464 28.35138421101771 27.86352684355239 26.492497447697293 28.299154545548266 27.815717912843343 28.707258985876607 28.652577623554173 28.480880052684327 27.499149809311184 28.52141554367359 27.69302407171845 28.163582411858524 26.64966704969923 27.581644301117244 29.16684331785471 63.0 22.0 31.0 44.0 80.0 99.0 89.0 103.0 87.0 94.0 73.0 55.0 101.0 82.0 83.0 111.0 147.0 84.0 74.0 64.0 90.0 67.0 88.0 87.0 3.0 2.0 3.0 2.0 2.0 4.0 1.0 3.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 -0.18160810618112322 0.9080725552559752 0.9266349541778063 GO:0016836 hydro-lyase activity molecular_function 27.877629370768794 28.048671160516 27.26670525753584 23.15835375659707 24.046154848052662 24.69302965562148 27.177904495680732 28.84449712320572 27.70326768048201 29.258231761002143 27.157511495183247 28.328455946498977 27.86276182638009 26.407593120788626 28.2889580705899 27.762248693293284 28.6837645994066 28.62617984335233 28.47968540527059 27.49559500641049 28.51673958428688 27.674139863864212 28.156870157948518 26.54190373284158 27.57201964425701 29.16516554806209 58.0 17.0 21.0 40.0 77.0 93.0 89.0 98.0 83.0 87.0 71.0 49.0 97.0 73.0 80.0 105.0 145.0 83.0 71.0 59.0 86.0 63.0 82.0 83.0 9.0 7.0 8.0 10.0 14.0 13.0 15.0 14.0 18.0 16.0 14.0 12.0 15.0 14.0 17.0 14.0 18.0 15.0 12.0 13.0 15.0 12.0 13.0 10.0 -0.17104178974720696 0.9080725552559752 0.9266349541778063 GO:0016838 carbon-oxygen lyase activity, acting on phosphates molecular_function 20.745675705615586 21.942846856592908 21.5138585340841 22.07994248751255 21.257875680553376 20.92284974054082 19.18178295499064 21.14686351255734 NA 20.604655419739547 19.828616036817483 22.278643917459526 16.982157731650652 22.363468990746927 21.149507229765142 23.008375406435466 22.75522126571419 22.848262703844128 16.6544339630917 18.832591685725546 18.74733712280911 21.428149972016087 NA 22.853292463934327 18.86027366136964 19.417998633313875 4.0 5.0 5.0 4.0 3.0 4.0 NA 4.0 4.0 6.0 2.0 6.0 4.0 6.0 3.0 5.0 1.0 1.0 1.0 5.0 NA 4.0 2.0 4.0 1.0 1.0 1.0 1.0 2.0 2.0 NA 2.0 2.0 2.0 1.0 2.0 2.0 2.0 3.0 2.0 1.0 1.0 1.0 2.0 NA 2.0 2.0 2.0 -1.1971711509773222 0.0409456971929358 0.06795243363934027 GO:0016840 carbon-nitrogen lyase activity molecular_function 28.21924831153921 26.36709192883177 26.49922615621157 25.55832821697937 25.653362299433013 24.70453276413189 27.758305994139985 25.78574890421576 28.275398345086817 26.40352210903995 28.487960994905148 27.02054423933021 28.40966467865148 26.256264838256463 28.37217808920229 26.15410360270477 27.406450208663998 25.68026327153921 29.62856268251463 27.92912949006621 27.488962586922213 26.19531571875186 28.69637592528011 25.70029405496739 28.3350560751392 26.31722834601376 58.0 46.0 46.0 33.0 97.0 72.0 124.0 119.0 124.0 94.0 130.0 65.0 118.0 72.0 101.0 69.0 157.0 173.0 99.0 62.0 128.0 59.0 125.0 89.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 1.8521563827074417 0.0009986863791802587 0.0031633517797384847 GO:0016841 ammonia-lyase activity molecular_function 27.99229896228898 24.90017089563883 25.839548306925536 23.623086127522416 24.047540982638914 21.13117063355881 27.592150367619638 24.176638109156734 27.900011701242967 25.075755933324352 28.225273132746505 26.19624371344507 28.0496313875448 23.105766682318443 28.057694210957717 22.543777488673925 27.10750622730433 22.606071603682075 29.58353953929859 27.020493847144948 27.211876073768412 24.35231130710168 28.57019898269901 21.524838339892526 28.15924030303259 25.49243493132153 27.0 8.0 5.0 3.0 56.0 20.0 77.0 38.0 79.0 38.0 67.0 18.0 78.0 13.0 51.0 12.0 110.0 94.0 44.0 17.0 70.0 11.0 69.0 29.0 4.0 2.0 2.0 3.0 8.0 4.0 8.0 4.0 8.0 5.0 7.0 4.0 6.0 4.0 9.0 5.0 9.0 9.0 5.0 4.0 8.0 3.0 9.0 4.0 3.092128066650151 0.00021985068263840352 0.0009941074345388681 GO:0016842 amidine-lyase activity molecular_function 24.641555206815923 25.322233624265397 25.053000943515844 25.016941615632767 24.83197768276281 24.17567196355441 23.73742773575163 24.996721661388122 24.225447256040805 24.953837186877337 23.76274675456713 25.7226347957111 26.028945345581022 25.84934435358996 24.198432735962644 25.696225006444244 24.490395966689444 25.32739540011463 23.513688516152808 25.426252577583604 24.51973644472093 25.703228069536948 24.53685223979773 25.26562984563405 24.833792521912308 24.940289518155236 31.0 30.0 32.0 21.0 31.0 42.0 24.0 56.0 29.0 46.0 54.0 36.0 24.0 42.0 43.0 46.0 32.0 52.0 38.0 41.0 43.0 35.0 46.0 53.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 2.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 -0.6806784174494744 0.005583616806378765 0.012692811975156102 GO:0016846 carbon-sulfur lyase activity molecular_function 26.490029644720522 22.820748658467732 23.05723874066303 23.367106480635556 22.946045562378718 20.84389460379665 27.6775377529338 22.113145376047395 28.232261275599534 22.211963357081427 27.340329224481174 23.297940426728765 26.501988331515275 22.36071794657055 27.34443817156669 22.99316205375988 25.80698895439142 23.32382739358004 24.12074605998443 23.67932006076981 22.28102959156672 21.959368837071036 25.3041217023029 23.012050244259328 24.59743169841689 22.58430857760188 8.0 7.0 8.0 3.0 24.0 6.0 35.0 6.0 30.0 7.0 24.0 4.0 32.0 8.0 12.0 12.0 22.0 20.0 10.0 5.0 25.0 9.0 22.0 8.0 1.0 2.0 2.0 2.0 7.0 3.0 6.0 2.0 7.0 1.0 5.0 2.0 6.0 2.0 4.0 3.0 8.0 8.0 6.0 1.0 6.0 3.0 6.0 2.0 3.66928098625279 0.0018227351663913985 0.005134928866041682 GO:0016853 isomerase activity molecular_function 29.520171747275878 29.936010158526482 29.386223543643393 28.871543958337913 28.65692103406075 29.355780747891327 29.23817035534811 30.2329558640024 29.5103257371181 30.44901683584859 29.40161002771591 30.1444334880657 29.667074405804343 29.335329545472625 29.552295771781825 30.05543729829603 29.371023320893013 30.31926929811437 29.73918801790596 29.95017979537857 29.92860005894681 29.790638651493 29.82306391574565 29.61200682445416 29.584940893011908 30.29114890732671 272.0 204.0 221.0 261.0 334.0 382.0 412.0 362.0 406.0 377.0 403.0 259.0 436.0 358.0 285.0 336.0 479.0 392.0 351.0 318.0 385.0 337.0 377.0 400.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 5.0 6.0 6.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 -0.41583841125060417 0.043308142810791976 0.0706517153305469 GO:0016854 racemase and epimerase activity molecular_function 25.70881540102146 26.41084970789364 24.15270903715369 22.12260197324183 22.59104314769725 21.921721027030806 25.109572623515053 27.32917756907105 25.508055005842056 27.697219027195555 25.346622441779843 26.6773621883118 26.136261228995533 24.723014981141358 25.294903739629174 26.36993083758077 25.8377131371288 27.149975726693306 26.055352116455694 25.56993931866076 26.479091045562548 25.712989755218004 26.553186885952066 25.576321729389228 26.059404594511445 27.16376949112719 23.0 13.0 10.0 11.0 32.0 28.0 29.0 39.0 33.0 39.0 29.0 30.0 21.0 23.0 21.0 26.0 42.0 33.0 21.0 20.0 30.0 30.0 22.0 30.0 3.0 3.0 3.0 2.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 3.0 2.0 4.0 4.0 4.0 4.0 3.0 3.0 3.0 2.0 4.0 2.0 4.0 -0.7020343068721786 0.29869755599497017 0.3712893923124729 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives molecular_function 23.25042034496881 22.8932765002776 21.11729086563818 21.50454500315753 19.899058164671647 20.032895395765983 23.630028437965322 24.218365320161446 23.46719593341733 23.528422036988484 23.88134447784114 23.16717941346011 23.7095588268618 22.627884324924487 22.01347698433768 22.047545027602915 22.61852827565949 22.66334129330894 23.85225886347063 22.543151783093343 23.40806362113437 21.416854597637247 23.72257920437297 23.840000132523087 23.510760460057192 22.74173172977436 10.0 11.0 6.0 7.0 18.0 16.0 19.0 23.0 19.0 22.0 17.0 16.0 12.0 9.0 12.0 15.0 34.0 23.0 8.0 10.0 22.0 21.0 16.0 18.0 3.0 2.0 4.0 4.0 3.0 4.0 4.0 3.0 5.0 4.0 3.0 3.0 4.0 3.0 3.0 3.0 6.0 4.0 4.0 3.0 5.0 5.0 4.0 3.0 0.3571438446912083 0.3556110610952391 0.43337630976650365 GO:0016860 intramolecular oxidoreductase activity molecular_function 25.57829369787361 25.46972693295424 26.030020115766145 23.453245651058694 25.774439909915827 26.29659852489984 25.114634275794447 25.773493112708177 24.86569650212471 25.137068817506872 25.028024694972114 26.27034057239183 24.78450617052666 25.31330563663077 25.33301190440444 25.67099454967157 25.33336651668531 24.09651513171081 26.750223452149854 25.722030759133464 25.756312623224936 25.506613168889203 25.17753129718617 25.550302391541084 25.665320647941552 24.47346417111193 28.0 13.0 23.0 23.0 30.0 39.0 28.0 21.0 26.0 32.0 27.0 17.0 41.0 27.0 28.0 24.0 71.0 36.0 30.0 21.0 33.0 19.0 31.0 30.0 2.0 1.0 1.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 0.10856676491937023 0.9080725552559752 0.9266349541778063 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses molecular_function 25.499640051793005 25.462389909389266 26.006028751983962 23.453245651058694 25.774439909915827 26.29037449298597 24.99292316110916 25.773493112708177 24.83911679175797 25.137068817506872 24.960636959204198 26.26034511476012 24.696225657272297 25.30709790451484 25.241990298654127 25.670610400588192 25.280541438463878 24.077271634605022 26.583558097892226 25.713316636398286 25.68397033129477 25.506613168889203 25.043652102570768 25.550302391541084 25.62573813672623 24.400374721630467 25.0 13.0 23.0 22.0 28.0 39.0 26.0 21.0 23.0 30.0 25.0 16.0 38.0 26.0 25.0 22.0 65.0 35.0 26.0 21.0 30.0 19.0 29.0 27.0 5.0 5.0 6.0 6.0 7.0 9.0 6.0 5.0 5.0 7.0 7.0 7.0 9.0 6.0 8.0 7.0 10.0 6.0 8.0 6.0 10.0 7.0 9.0 7.0 0.037250142403738806 0.9080725552559752 0.9266349541778063 GO:0016866 intramolecular transferase activity molecular_function 28.918349281675702 29.21040953407837 28.811373192011896 27.88310503413516 28.12062897361025 28.425414757668392 28.7897055976948 29.475586167638287 28.646700056190358 29.723351000762506 28.79953320341688 29.46627592592968 29.170146505553994 28.63731825552326 28.937727711359386 29.277435060430133 28.77561020495181 29.55154603949771 28.91636686861477 29.28299742817124 29.32136480047439 29.199427989719826 29.32852524373106 28.69873846752809 29.019260538757038 29.76271749825167 139.0 88.0 120.0 141.0 168.0 162.0 191.0 178.0 184.0 179.0 197.0 107.0 224.0 173.0 140.0 168.0 189.0 180.0 200.0 166.0 195.0 161.0 186.0 194.0 5.0 4.0 4.0 4.0 7.0 7.0 6.0 8.0 6.0 6.0 8.0 6.0 6.0 5.0 6.0 7.0 8.0 7.0 6.0 6.0 5.0 6.0 6.0 6.0 -0.292060252402667 0.2040238704744366 0.2705863871967023 GO:0016868 intramolecular transferase activity, phosphotransferases molecular_function 27.629789687845122 28.491638154654694 28.24609142547373 27.80727411058167 28.113500373584234 28.41454885555984 27.34942991257906 28.779344564325857 26.99896906989556 28.343328412591184 27.630234169097122 28.71882096328683 27.44542053744184 27.995262691810908 27.49534155156477 28.941068658049893 27.01533151839894 28.905006239885136 27.27640224149274 28.570366635619497 28.26058436798213 28.73234532752533 27.57774639923047 27.90199616600565 27.41096114856682 28.21908868732994 109.0 75.0 113.0 135.0 119.0 118.0 138.0 127.0 137.0 136.0 139.0 66.0 164.0 132.0 96.0 122.0 133.0 127.0 152.0 123.0 144.0 119.0 133.0 149.0 4.0 3.0 3.0 3.0 6.0 4.0 7.0 6.0 7.0 5.0 6.0 6.0 6.0 5.0 6.0 7.0 6.0 6.0 5.0 4.0 5.0 3.0 6.0 6.0 -0.8618484668095725 0.00042856814449695465 0.0016457016748683058 GO:0016874 ligase activity molecular_function 29.314389896860405 29.13891697241827 28.24264124768611 28.203306657465305 27.778358625397182 28.70686568119523 29.143998853441442 29.172740898986262 29.74303212759757 29.30742361594016 29.70918415478569 29.314619311465755 29.6197867584844 28.79200371586273 29.303316042629927 29.22026486383121 29.15660883386328 29.288371112404004 29.57619055416368 29.299167397768677 29.303285437863522 28.85495344568271 29.60805704861751 29.122497408929163 29.436768849379558 29.796945342968375 312.0 296.0 318.0 371.0 634.0 574.0 796.0 627.0 801.0 578.0 799.0 443.0 706.0 564.0 540.0 597.0 918.0 728.0 471.0 464.0 761.0 526.0 748.0 629.0 4.0 5.0 4.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 0.17547292444213625 0.18420928818665294 0.2488021554728819 GO:0016877 ligase activity, forming carbon-sulfur bonds molecular_function 23.757212671824213 24.5112800698957 23.30063738088089 24.582813543003745 24.98888872305757 25.52286333541289 22.213033818665146 25.128049929806448 23.411837632501964 24.09513872325342 23.51938204131182 23.530960825239678 23.22715106384953 24.61847825952332 22.173840543290147 24.54810669433517 21.5013502156385 24.01541523742219 24.78987312543241 24.664578309921946 23.96131777439613 24.25975654605145 24.559605044332447 23.96714638224979 23.37549325573431 23.982760759166666 14.0 15.0 34.0 33.0 21.0 21.0 43.0 16.0 37.0 13.0 33.0 14.0 21.0 14.0 8.0 17.0 50.0 19.0 29.0 15.0 36.0 21.0 41.0 17.0 1.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 -0.7540673980714878 0.011074437676156606 0.022291771322328135 GO:0016878 acid-thiol ligase activity molecular_function 23.62702498131835 24.493183135316205 23.30063738088089 24.40577755832845 24.984291966900077 25.52286333541289 21.838438703610286 25.128049929806448 22.82132346812531 24.07793524257761 23.269525011396734 23.530960825239678 22.864272673623066 24.61847825952332 21.752545151169013 24.545818615898085 21.063499823155208 24.01541523742219 24.781979343772182 24.651992889551693 23.96131777439613 24.25975654605145 24.535658236323385 23.95083569636693 22.89573205215249 23.982020451093373 14.0 14.0 33.0 33.0 15.0 21.0 30.0 14.0 28.0 13.0 25.0 14.0 14.0 13.0 6.0 17.0 48.0 17.0 29.0 15.0 31.0 19.0 27.0 16.0 2.0 2.0 3.0 2.0 3.0 2.0 4.0 2.0 4.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 4.0 2.0 2.0 2.0 4.0 3.0 3.0 -0.8661581539978549 0.013042519940568903 0.025877686622941164 GO:0016879 ligase activity, forming carbon-nitrogen bonds molecular_function 26.92891475487116 27.04027440752939 26.001041979512486 26.28499975265823 26.05836520546733 26.64385450832797 26.74874360066893 27.03848635796623 27.31390063570982 26.83882536921729 27.526359888815463 27.21658004450481 27.076376555653987 26.89900962356958 26.993257073970018 27.346924486451826 26.99162513631164 27.30628157998497 26.903874163154732 27.350492910986556 25.61599388160776 26.57162130246141 27.19788471279364 27.46245344928849 27.453028632301642 27.041550164510358 98.0 117.0 103.0 128.0 139.0 221.0 163.0 225.0 167.0 206.0 204.0 171.0 176.0 221.0 135.0 242.0 184.0 226.0 121.0 164.0 156.0 208.0 183.0 212.0 8.0 8.0 7.0 8.0 12.0 8.0 11.0 8.0 9.0 10.0 9.0 10.0 9.0 9.0 8.0 8.0 11.0 10.0 7.0 8.0 10.0 10.0 10.0 8.0 -0.11135965265823344 0.6441672226837103 0.7073013587238495 GO:0016881 acid-amino acid ligase activity molecular_function 23.67180124293867 24.131887833158927 21.68312483887196 22.96647698910364 20.82717221125451 23.70252132715424 23.589448234914595 24.22536986343781 24.32667468377121 23.919054127981795 24.238079332102817 24.38660622762161 24.17938665361961 23.93067285844565 23.140834336152892 24.2756083808372 23.88687061186061 24.32892957557053 23.801169566891442 24.17139700445121 22.22002550401444 23.310877439172025 23.71441786344857 25.080852491040698 24.555608779823388 24.19328982334445 12.0 23.0 10.0 24.0 35.0 44.0 42.0 46.0 47.0 60.0 59.0 40.0 42.0 53.0 37.0 58.0 55.0 59.0 23.0 34.0 40.0 49.0 51.0 50.0 8.0 7.0 5.0 7.0 7.0 7.0 6.0 9.0 6.0 10.0 10.0 10.0 9.0 9.0 8.0 9.0 9.0 11.0 5.0 9.0 8.0 7.0 10.0 9.0 -0.4600865902202571 0.13332693177434943 0.18549833985996442 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor molecular_function 25.093224066601238 26.41864857033089 25.33918392213365 25.74418327873722 25.32280910615543 26.08504669358487 24.65315912749993 26.46805057164905 25.118360913766885 26.21590404219438 25.192473437935767 26.58598964044497 25.603117110598674 26.32400069481761 24.83109978265393 26.79872456207325 24.954317589693947 26.808235500752787 24.7926887554808 26.487309202180114 24.536780955514498 26.07517826180943 24.739740594603237 26.763534657153805 25.552756977086943 26.263914635130224 54.0 73.0 65.0 83.0 53.0 148.0 65.0 143.0 68.0 110.0 88.0 97.0 69.0 132.0 58.0 152.0 77.0 116.0 59.0 106.0 64.0 123.0 71.0 125.0 6.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 5.0 4.0 6.0 5.0 6.0 4.0 5.0 5.0 5.0 5.0 5.0 -1.3254245037296535 3.225641456243767e-05 0.0005099643033035255 GO:0016885 ligase activity, forming carbon-carbon bonds molecular_function 24.542355815237052 25.13370313371125 22.3913710933356 18.494454018617112 21.601457757116126 20.59801609757832 24.68152887908232 25.42332626657346 25.015945067055977 26.48462248309062 25.36892838978686 24.767226617621564 25.045621313704252 24.37850807963329 23.982518178192965 24.89383065838037 25.110771907924594 26.01888646957343 24.331436948695263 24.258839735091637 24.474233922525805 24.77027366054222 24.29116175488993 23.961533564631715 24.73714339284759 26.363569437950893 10.0 2.0 8.0 2.0 34.0 34.0 34.0 48.0 35.0 26.0 29.0 16.0 24.0 31.0 24.0 36.0 30.0 26.0 25.0 29.0 33.0 20.0 31.0 35.0 2.0 1.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 -0.5913473184741989 0.5637028616507731 0.6360770084449954 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters molecular_function 24.699191928932816 24.744872662998446 24.318588929661683 22.646751456062393 20.71923109683958 21.363121373005786 23.856719280586344 23.11481555922884 25.6403183194103 25.048126556342034 24.49263167019884 22.94915900457081 23.09703267016632 23.21290246608179 22.153986865963844 21.77704367843163 24.101091012533665 22.656467614088626 26.89647112069081 27.836161421512973 25.5627609774264 21.069151044738266 18.830685554588502 23.359962691033463 22.640769111153308 21.834042838019275 8.0 10.0 6.0 11.0 4.0 11.0 3.0 7.0 4.0 10.0 2.0 13.0 2.0 15.0 3.0 13.0 5.0 19.0 4.0 7.0 1.0 19.0 4.0 4.0 3.0 2.0 1.0 1.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 -0.045680734065630446 0.3556110610952391 0.43337630976650365 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters molecular_function 24.717573647616984 24.83398177983889 24.383303851280875 22.735034662983534 21.388124727394413 21.621213847706045 23.86163060685924 23.693669105749983 25.6403183194103 25.116834469915734 24.504833867173534 23.138960956694497 23.2689332105202 23.37582300802093 22.159608431321004 22.18708158820881 24.101091012533665 22.944164847959215 26.898940629728628 27.848885244377783 25.56823038903247 21.228006028648288 19.062705523041405 24.005240603609323 22.71047857324643 22.171257936788503 10.0 12.0 8.0 14.0 5.0 18.0 3.0 11.0 6.0 12.0 6.0 16.0 3.0 19.0 3.0 17.0 6.0 22.0 5.0 9.0 2.0 27.0 6.0 7.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.11640813222190616 0.4189234409463829 0.5022252202700153 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters molecular_function 22.89594457773705 24.96395075128704 24.19331606440013 24.58148637082941 23.948200361328464 24.67913362348948 21.164547001174366 25.00891364959077 21.062276211098943 24.57248625001257 21.58232872433824 25.055744507460798 22.80637934273284 25.21415505277198 23.506322068023852 25.389054663912397 21.48719514255571 25.077123649472213 23.436356496006265 24.90114484922791 23.29484230609979 24.83539256317978 20.747947047717663 25.36421588396503 22.258354306538052 24.542700012933878 28.0 40.0 27.0 39.0 14.0 44.0 10.0 41.0 19.0 38.0 24.0 39.0 24.0 48.0 12.0 48.0 34.0 34.0 24.0 39.0 10.0 46.0 23.0 33.0 2.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 1.0 2.0 2.0 3.0 3.0 -2.068006173549989 3.225641456243767e-05 0.0005099643033035255 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors molecular_function 30.243393536649 30.692011876672073 30.49609327639153 30.13832597248921 30.649671696750413 30.75390934195041 30.09062216257985 30.734246580942234 29.764009850468828 30.789391818573762 29.99269357956572 30.572153517827463 29.96861519166836 30.193447115799362 30.575609924306413 30.938242825847958 30.03856386182768 30.698836643555516 30.73658167774944 30.878317343148044 30.316415203907805 30.77831309675443 29.69490073215537 30.49953027554202 30.13814004309789 31.050209744722363 250.0 152.0 252.0 315.0 304.0 272.0 325.0 281.0 290.0 289.0 328.0 222.0 354.0 296.0 247.0 274.0 418.0 346.0 354.0 264.0 379.0 280.0 298.0 321.0 7.0 4.0 5.0 6.0 7.0 6.0 5.0 6.0 6.0 7.0 7.0 6.0 6.0 6.0 7.0 6.0 7.0 6.0 7.0 6.0 7.0 6.0 7.0 7.0 -0.4486183400230743 0.0018227351663913985 0.005134928866041682 GO:0016987 sigma factor activity molecular_function 20.64812124197445 20.853358222502674 19.255216557617565 18.62814863117337 20.23989932717754 22.059458371779836 20.6512871551688 18.883995544238413 20.60399692363725 21.59415399446411 20.622344388357547 19.431283583017525 21.100562422801328 18.845402037634038 19.962250320240138 21.8737638922221 20.926358702002613 21.196217673750734 20.24886093634622 21.477611757815207 21.156397779065344 20.884408184688827 20.55323450906592 19.8909785910904 21.3186399675212 20.010666015492454 3.0 1.0 3.0 4.0 4.0 2.0 4.0 3.0 6.0 6.0 4.0 2.0 2.0 2.0 5.0 2.0 6.0 5.0 7.0 2.0 5.0 3.0 6.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.20523698052822326 0.9539596927720386 0.9577970205788449 GO:0016999 antibiotic metabolic process biological_process 28.604931101779364 27.22242517132509 27.058421136273214 26.42487149246506 26.438312582880158 26.390764110149302 28.310114072657104 27.84698816281001 28.22261693931873 27.40531169383629 28.85165729307149 27.52139541999475 28.990869563501164 27.07793815334005 28.436795221149374 26.329497870269066 27.95561228456675 26.81486011035436 29.725861841682363 28.032803360634734 28.77675472909323 26.96148914276925 29.148169849316503 26.879112160372728 28.7067970757798 27.68925489516563 97.0 52.0 81.0 94.0 135.0 90.0 150.0 87.0 163.0 122.0 168.0 70.0 187.0 64.0 136.0 81.0 250.0 159.0 157.0 69.0 159.0 57.0 147.0 115.0 6.0 6.0 7.0 8.0 9.0 7.0 7.0 7.0 6.0 8.0 8.0 8.0 9.0 6.0 8.0 7.0 10.0 9.0 8.0 7.0 7.0 7.0 7.0 9.0 1.3825059304542755 0.0012242832644312096 0.0037265988146589013 GO:0017001 antibiotic catabolic process biological_process 22.882574071220713 22.36542694852236 21.942837370464698 18.368131921185814 22.612425161404918 24.620573961263556 21.707339391670605 22.772854349448647 20.67977670948752 19.180723486769324 22.956014762802898 20.679174756448255 23.305914874844504 23.305486559092074 24.255927580563746 21.70271852743346 22.467152894659904 22.17780821206901 24.18382282631281 20.17575797001456 22.11151900791143 22.460739095620426 21.638881019856214 19.347542494966874 22.52954104490181 21.57260012300277 11.0 3.0 13.0 21.0 12.0 7.0 7.0 3.0 11.0 7.0 15.0 12.0 28.0 10.0 16.0 7.0 28.0 8.0 10.0 9.0 7.0 4.0 11.0 14.0 1.0 1.0 2.0 3.0 2.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 3.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 0.5171471226983542 0.0832645166635504 0.12534875367444018 GO:0017076 purine nucleotide binding molecular_function 32.061541181906 31.909381846447314 31.30748995391971 31.246118063049607 31.26274967968156 32.03849684132208 31.82183095491785 32.038966807639035 32.225263852584625 31.83321965306337 32.385495429027195 32.02543176491776 32.184834164095825 31.639979939895905 32.11730021222365 31.9783567009584 31.643996619674645 31.83817458508766 32.6529020190073 32.144654811909774 32.24809359884932 31.977476267939164 32.146182410787894 31.940013346351773 32.105492191301195 32.00862836954427 1560.0 1648.0 1460.0 2122.0 2310.0 2594.0 2775.0 2431.0 2813.0 2464.0 2739.0 2032.0 2890.0 2476.0 2116.0 2507.0 3568.0 3138.0 1918.0 2000.0 2627.0 2430.0 2642.0 2516.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 0.15215933545868765 0.10596880912720232 0.15148805703407617 GO:0017111 nucleoside-triphosphatase activity molecular_function 30.985452811932177 31.08754040556372 30.69648929927328 30.36164780185954 30.555228399832426 31.004867653283462 30.61165933214292 31.03671400566075 31.025118332462593 31.08989805124802 31.09571036986789 31.23136123410768 31.00914113498234 30.84031106556859 31.06211034135384 31.295440290040652 30.549101849486608 31.139832047651982 31.42276947659979 31.136029413803854 31.434583966797234 31.15187910106116 31.0733869985602 31.2278224521431 30.938591283020376 31.30525262439108 919.0 947.0 726.0 1188.0 795.0 1247.0 1004.0 1174.0 1033.0 1283.0 1016.0 1162.0 1106.0 1342.0 795.0 1221.0 1134.0 1385.0 874.0 1127.0 911.0 1235.0 988.0 1357.0 3.0 3.0 3.0 3.0 4.0 4.0 4.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 4.0 3.0 -0.1020875936315413 0.18420928818665294 0.2488021554728819 GO:0017144 drug metabolic process biological_process 30.55351264116476 31.088173272831717 30.509722090370666 30.39121700808867 30.21488105112489 31.06820616925288 30.16770410979205 31.29932286923513 29.95646497159064 30.995691398447622 30.646738798294678 30.9857750518545 30.613866265813776 30.548249314740428 30.942766989638034 31.43805632885513 30.040253957529067 31.565279625298718 31.456296485425728 31.331836193751982 30.48303188693873 30.966611126165205 30.471484930485243 31.096725790523948 30.442756240713077 30.946592187478274 562.0 491.0 645.0 759.0 690.0 833.0 748.0 746.0 792.0 791.0 810.0 566.0 879.0 742.0 660.0 776.0 1204.0 929.0 831.0 648.0 819.0 688.0 781.0 786.0 16.0 18.0 17.0 16.0 18.0 16.0 18.0 15.0 18.0 19.0 18.0 19.0 19.0 16.0 19.0 16.0 21.0 17.0 17.0 15.0 18.0 20.0 19.0 18.0 -0.5346606316669558 0.0032349119169146935 0.007931571851295751 GO:0018130 heterocycle biosynthetic process biological_process 32.74071485718869 33.49193861119392 32.86548476821765 32.885478503025645 32.48383388071995 33.404469587602556 32.409873218205554 33.65050138511278 32.28973746413357 33.434391268645896 32.94326825398319 33.43824543266149 32.92597522248745 33.089500939779604 33.04844883079259 33.83104106355798 32.28669825803273 33.868563214903034 33.29001964705683 33.655490143583265 32.79327650073318 33.349452999145754 32.48468682790388 33.631368511529075 32.670885911583646 33.36246807847052 3798.0 3832.0 3585.0 4505.0 4208.0 5941.0 4716.0 5622.0 4831.0 5685.0 5274.0 4341.0 5196.0 5616.0 4198.0 5782.0 6541.0 6288.0 4782.0 4717.0 4993.0 5344.0 5096.0 5749.0 11.0 11.0 10.0 11.0 12.0 11.0 13.0 11.0 12.0 13.0 13.0 13.0 12.0 11.0 12.0 11.0 12.0 11.0 11.0 10.0 12.0 13.0 12.0 13.0 -0.7512237540052311 0.00010962068302139599 0.000648372570666835 GO:0018193 peptidyl-amino acid modification biological_process 21.684757785427042 22.33992956087376 20.9966945375052 20.852967739396206 23.29955832668919 24.42246871892808 19.827960693700078 21.309803400983032 14.133941451958805 21.550667168010698 21.222955555735336 21.234269316169648 22.31283986007241 22.571589076078638 18.62190841016141 22.680072983874144 17.54591274186464 21.304999171195927 22.63796881750465 21.042413116082887 22.614229721803678 22.102814112894727 22.13069629771835 22.772135140872656 20.30475802613769 20.792218857757504 4.0 4.0 10.0 16.0 8.0 5.0 1.0 6.0 13.0 11.0 10.0 5.0 3.0 7.0 2.0 8.0 23.0 6.0 5.0 5.0 8.0 6.0 7.0 5.0 1.0 1.0 1.0 3.0 4.0 1.0 1.0 2.0 3.0 3.0 3.0 1.0 2.0 1.0 2.0 1.0 3.0 2.0 2.0 1.0 3.0 1.0 4.0 2.0 -0.6551717754467177 0.2040238704744366 0.2705863871967023 GO:0018454 acetoacetyl-CoA reductase activity molecular_function 21.909130668837513 22.393396308027455 24.090979656285683 22.035029234076628 21.91159233127504 21.316560003048306 19.49733986311245 17.609933536144474 NA 20.098144653716304 18.187505330908827 21.683899044947424 19.683313524212245 20.315213434568538 21.41870240842926 21.94422760781447 17.708742341579693 15.779710685505608 19.20301234620602 23.772174884205985 22.677338521739287 19.63532633749316 22.389311249029088 24.29157194093369 21.859109444883998 23.67974664526731 8.0 5.0 4.0 6.0 3.0 1.0 NA 3.0 2.0 4.0 3.0 3.0 4.0 4.0 1.0 1.0 3.0 5.0 6.0 2.0 4.0 4.0 5.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4842656391899425 0.7119231506921901 0.7679171063646095 GO:0018492 carbon-monoxide dehydrogenase (acceptor) activity molecular_function 20.993280142896445 23.43028289690333 17.496838881722955 NA NA 16.257121098593878 19.203249257143213 22.019363920328196 NA 22.71775538559123 18.598320727189144 22.306332424871677 23.136170969108864 23.84546499901693 NA 22.35707979482989 21.74934572383988 24.503163482156143 21.16593858153765 21.437430505555696 20.197499719407173 23.33648633685335 17.510366469332684 21.04876890117796 20.088606962147328 25.51956106816505 2.0 NA NA 1.0 3.0 10.0 NA 11.0 2.0 9.0 10.0 11.0 NA 12.0 5.0 19.0 4.0 5.0 4.0 14.0 2.0 4.0 4.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.4370027540068833 0.016703403847161492 0.03216951852045917 GO:0018580 nitronate monooxygenase activity molecular_function 22.745610837705666 23.84736975249616 21.97135025221095 22.70314049559548 22.730606098608874 24.33164743059648 22.24933476752181 23.909801743887442 22.930284715170888 24.029061814531 23.298678912223433 23.71476440567049 23.33150379462512 22.284543007748066 23.664897511419767 24.73782764167368 21.162875805393192 24.17973786654971 22.27469507617207 24.151511324854738 22.2657708552265 23.754644172338697 22.608678298400392 22.914669141494144 22.800738367566552 23.711978351882657 5.0 5.0 5.0 3.0 8.0 10.0 11.0 8.0 9.0 9.0 8.0 5.0 16.0 9.0 5.0 9.0 8.0 11.0 7.0 7.0 10.0 7.0 8.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1017589147904943 0.0014961642897455532 0.004424675435076897 GO:0018801 glutaconyl-CoA decarboxylase activity molecular_function 25.845257502567506 25.672413743595467 23.758756115826213 NA 17.582267197526214 NA 25.77243219184157 26.391382879076186 26.099301435099395 26.86566561627492 26.364703112807717 25.471513359436308 26.56841418061953 22.18473904223532 26.67342331713043 23.44093457961264 25.72624143270949 26.234030678013077 25.10582223315013 25.531406850528306 25.559958505505232 24.579437063085393 26.048657428593568 24.05586450294632 26.186200054912074 26.452730650702343 4.0 NA 1.0 NA 4.0 4.0 6.0 6.0 5.0 5.0 4.0 1.0 7.0 3.0 4.0 4.0 5.0 4.0 6.0 6.0 3.0 2.0 5.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.1728437589720393 0.6443923436450455 0.7073013587238495 GO:0019134 glucosamine-1-phosphate N-acetyltransferase activity molecular_function 21.75654802308436 23.49283971604846 24.168475409888572 23.089245003438624 21.986295444779405 23.932965390662137 19.35329758423889 23.447289950836893 18.540267759445427 23.39749139055819 20.90284007140296 23.56654517618846 21.62195547306797 23.51958310320806 21.42628044380263 23.626391724383012 20.551278986011027 22.80259070975454 19.639250013828004 23.949205748325486 22.035137193483838 23.56539641156923 19.861871755698036 23.748095310580677 21.440200989549826 22.700150200540584 9.0 8.0 9.0 15.0 3.0 11.0 2.0 12.0 7.0 11.0 8.0 9.0 8.0 11.0 5.0 11.0 5.0 12.0 7.0 12.0 4.0 10.0 9.0 17.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.7362916929641017 0.0005320055051392492 0.0019244720881558927 GO:0019152 acetoin dehydrogenase activity molecular_function 23.889935458394145 25.921938622846035 22.885178990672426 26.040838804189967 26.419444574990173 25.97550813490665 21.455860195799524 25.000659843676605 22.391330943537607 25.436839237590323 21.817367255487977 23.70419837300089 23.704575196877478 25.38445357000629 17.522688248133218 26.227428133030077 17.93678337066629 26.32747896095927 23.322338057541426 26.5185799653213 25.273858995678548 26.10086136835425 18.932801942360502 26.308152043262826 23.429631723797 26.206707053537738 9.0 14.0 15.0 20.0 4.0 21.0 10.0 15.0 9.0 10.0 10.0 15.0 1.0 20.0 1.0 18.0 12.0 12.0 14.0 19.0 3.0 14.0 8.0 9.0 NA NA NA 1.0 NA 1.0 NA 1.0 1.0 NA NA 2.0 NA 1.0 NA 1.0 NA NA 1.0 1.0 NA NA NA NA -2.03200316445189 0.0008121171348941295 0.002709952364566507 GO:0019200 carbohydrate kinase activity molecular_function 24.43671451623333 25.849214762244173 25.415378889284 25.385079690478364 25.45002881563693 26.00588494151113 23.250309891257743 26.004195164344484 24.243557894519988 25.66890119235013 24.116532350440675 26.117635357807856 24.54008540085949 25.93135170469952 24.34236552183488 26.07895635832817 24.121422508316808 25.853130070240432 24.24432724733403 25.73160297522523 24.038959179571094 25.65621170253752 23.97365314044116 26.05700605532148 23.965702016567125 25.480804931137282 26.0 40.0 38.0 32.0 25.0 51.0 30.0 47.0 39.0 44.0 32.0 36.0 35.0 43.0 28.0 51.0 45.0 52.0 32.0 44.0 27.0 39.0 32.0 43.0 3.0 3.0 4.0 3.0 5.0 4.0 4.0 3.0 7.0 5.0 7.0 4.0 4.0 3.0 4.0 3.0 6.0 5.0 5.0 2.0 5.0 2.0 4.0 3.0 -1.4125002460108433 5.312128159411724e-05 0.0005099643033035255 GO:0019202 amino acid kinase activity molecular_function 22.405065748219275 22.685446602083047 21.484768877797027 21.63939059116184 20.87066258727645 21.126892876453585 22.092450718463176 22.99535584463089 19.266913453478654 23.05068528955237 20.439030167513945 22.73882859769093 22.49141061187007 22.778549526603108 24.87556257567512 22.305861942720046 20.315565619970933 22.445990045705848 22.58918592505263 23.18284311813517 21.96088808921387 21.844403904080053 22.26304242117559 23.129517797951692 20.82857453951185 23.361779542012467 6.0 7.0 3.0 6.0 9.0 17.0 3.0 14.0 7.0 16.0 13.0 11.0 5.0 11.0 7.0 13.0 21.0 15.0 13.0 7.0 16.0 12.0 10.0 15.0 1.0 1.0 1.0 1.0 2.0 3.0 1.0 2.0 1.0 1.0 2.0 1.0 1.0 1.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 1.0 2.0 -0.28038085386377176 0.02092133533779403 0.038284203081476474 GO:0019205 nucleobase-containing compound kinase activity molecular_function 25.684527424174124 25.074716527078532 24.25670708404502 23.412508135673733 23.37976935120244 24.24774692869896 26.543710559877802 25.465383963047053 25.600150169741763 25.93702190043652 26.34927872459549 25.53869134609036 26.57675996395525 24.62606835867471 25.01094473888981 24.759986400855986 25.670727580520268 25.24000412765925 25.995268796176447 25.09743784728177 24.886631103313732 24.064771791467408 25.42401065175537 24.868301860436894 25.62506369268425 25.729892017898365 31.0 11.0 16.0 18.0 38.0 29.0 34.0 33.0 38.0 39.0 52.0 25.0 39.0 30.0 36.0 37.0 52.0 39.0 36.0 19.0 49.0 34.0 41.0 37.0 3.0 2.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 0.609810897095592 0.0940685547103812 0.1379524750629327 GO:0019213 deacetylase activity molecular_function 25.356220404987546 24.19504273383405 25.653952068117754 22.5892439616627 21.90089091471674 23.596332217565056 23.80843091854452 24.40304474808897 24.75076190157487 24.507970095718754 25.92712775700739 25.776095196862197 26.03188240187855 24.586177938109252 25.195751429559326 22.839273776759924 24.40336256867633 23.08478724216342 25.435648572762585 24.13621109333633 26.33510226631321 24.148782641520505 26.161904065150647 23.275040284440927 24.072327860645558 24.194396999726838 18.0 14.0 8.0 16.0 11.0 32.0 14.0 19.0 14.0 20.0 14.0 27.0 22.0 19.0 14.0 21.0 18.0 18.0 12.0 27.0 9.0 19.0 16.0 19.0 5.0 5.0 2.0 3.0 4.0 6.0 4.0 5.0 4.0 4.0 4.0 5.0 4.0 5.0 4.0 5.0 3.0 3.0 3.0 4.0 3.0 4.0 4.0 4.0 1.1611776711534958 0.024343383653741054 0.04309296851045225 GO:0019216 regulation of lipid metabolic process biological_process 20.758800964402138 23.648202523529115 19.041541616741096 23.11552662594623 16.80253573248276 23.4531044018516 20.553031196648355 23.62701286450559 21.12362431855102 23.843828761187762 21.90989705157476 24.13958746030871 16.889243061109436 21.99067199805663 NA 23.33361732016477 21.215257665836344 25.19030125849611 20.3697831290561 23.910180600298986 NA 21.59995049527676 21.61272291913899 24.05563954867805 21.07400321916452 20.301723201613555 8.0 16.0 8.0 8.0 9.0 16.0 8.0 8.0 8.0 16.0 8.0 16.0 NA 8.0 9.0 16.0 14.0 9.0 NA 8.0 16.0 16.0 9.0 8.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 NA 3.0 3.0 3.0 5.0 3.0 NA 3.0 3.0 3.0 3.0 3.0 -2.889401559126977 0.0007714494638696247 0.002637723098381621 GO:0019218 regulation of steroid metabolic process biological_process 18.81338937569021 22.227832257599808 17.626504117462254 21.70048912666737 15.387498233203914 22.038066902572755 16.779595709460967 22.21197536522675 19.708586819272174 22.428791261908913 20.49485955229591 22.724549961029872 15.47420556183059 20.575634498777784 NA 21.918579820885924 17.832795204320984 23.77526375921727 17.678979733223837 22.440866583984967 NA 20.184912995997912 20.19768541986015 22.64060204939921 17.76804938142643 18.886685702334713 3.0 6.0 3.0 3.0 3.0 6.0 3.0 3.0 3.0 6.0 3.0 6.0 NA 3.0 3.0 6.0 3.0 3.0 NA 3.0 6.0 6.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 -3.414442881909597 0.00028718585599843356 0.0012027112358592117 GO:0019219 regulation of nucleobase-containing compound metabolic process biological_process 26.624468315732003 27.715377891228474 26.729307598572284 27.354158495645517 27.15030602660736 27.11561722517266 25.90195405319541 27.954688995186853 26.609938124404092 28.16749302050351 26.555499760630962 27.893435754977396 26.694344956541034 27.45868333210031 26.58762905367185 27.61303091041201 25.42725440329073 27.616103109816518 27.146686728438173 28.300997914630297 26.981424781778824 27.294068173346023 26.150837621028074 27.470323227830658 26.67820867238337 27.83780037771969 132.0 158.0 129.0 136.0 139.0 203.0 164.0 225.0 187.0 190.0 209.0 176.0 157.0 165.0 114.0 181.0 250.0 245.0 168.0 147.0 145.0 184.0 215.0 231.0 4.0 2.0 2.0 2.0 3.0 3.0 5.0 6.0 5.0 5.0 6.0 4.0 5.0 3.0 4.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 4.0 -1.0909095754964717 5.312128159411724e-05 0.0005099643033035255 GO:0019222 regulation of metabolic process biological_process 31.840335795549283 32.492580612786945 31.930912280029393 32.10518150260078 32.04903802557146 32.38203728188807 31.449591982450734 32.73885699605983 31.672629978724107 32.69628586879979 31.839558607105197 32.61773120551898 31.87927393570761 32.331110075966556 31.82030615364409 32.384346660204685 31.21845369751275 32.39901019694192 32.30367942811499 32.93699338450206 32.0281974060921 32.19766195966216 31.69214153599016 32.32943553438428 31.901796843368693 32.56687698034924 2902.0 3303.0 2822.0 3240.0 3092.0 4514.0 3527.0 4661.0 4078.0 4180.0 4152.0 3645.0 3206.0 4123.0 2628.0 4325.0 5233.0 5095.0 3578.0 3192.0 3210.0 4282.0 4168.0 4891.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 7.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 -0.652244817237662 5.312128159411724e-05 0.0005099643033035255 GO:0019238 cyclohydrolase activity molecular_function 22.46329316783648 22.206658993084773 22.50971644553514 21.329958087331494 19.849293579217893 22.081718996628094 22.641273317571358 22.60374626035636 21.81715840766704 21.94261773387908 23.44712525593385 22.671962820341648 23.37057692221397 21.832129348110506 21.75904642505288 22.85605210364969 22.62289440589754 21.705072196654616 21.126317783186604 23.036816862584683 22.333780923757683 21.802862541749068 21.837189911847734 21.664703268518142 23.040333544599036 21.77490428821115 2.0 5.0 5.0 14.0 16.0 13.0 9.0 20.0 18.0 13.0 22.0 10.0 13.0 14.0 14.0 9.0 9.0 15.0 9.0 12.0 13.0 10.0 19.0 10.0 1.0 3.0 1.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 0.25663417475170647 0.4884223166225936 0.5675521891480417 GO:0019239 deaminase activity molecular_function 21.45217413827746 21.15703719049096 20.546054465566336 20.76508391349164 20.714624792952254 19.80542009099472 19.4688013801178 20.92657367315995 17.972584827491648 21.919283036720113 20.2886020349518 22.844240491323994 21.34670832161984 20.721453097492045 19.676309571628106 20.397497580620886 18.670162658764397 19.58185600803197 24.26554483815245 21.58483852735146 20.78210872271932 20.166304492235497 20.31261871896502 20.131741704157783 20.713121392437667 21.257137782935537 5.0 4.0 5.0 4.0 3.0 10.0 4.0 16.0 3.0 21.0 7.0 6.0 5.0 5.0 2.0 5.0 9.0 10.0 12.0 6.0 6.0 9.0 3.0 7.0 3.0 4.0 3.0 2.0 2.0 5.0 3.0 5.0 2.0 6.0 5.0 3.0 4.0 4.0 2.0 3.0 6.0 6.0 4.0 4.0 3.0 4.0 2.0 4.0 0.29513694778649935 0.24821307898992373 0.31935043564889154 GO:0019262 N-acetylneuraminate catabolic process biological_process 22.35431806263149 21.002212902819508 21.942837370464698 18.368131921185814 22.56944849878261 18.76376166611821 21.656921128941608 22.772854349448647 20.67977670948752 19.180723486769324 22.956014762802898 20.61071963190197 22.159651115595707 18.10362841372795 23.11362569728941 21.70271852743346 22.421414835082803 22.17780821206901 23.013794489558894 19.638266819194342 21.85646971117628 22.15349849269463 21.638881019856214 18.731415406695078 22.52954104490181 19.423517360618018 11.0 3.0 11.0 3.0 11.0 7.0 7.0 3.0 11.0 6.0 8.0 1.0 13.0 10.0 13.0 7.0 16.0 5.0 6.0 5.0 7.0 2.0 11.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.3521051598119804 0.004669131805023211 0.010994483948432015 GO:0019264 glycine biosynthetic process from serine biological_process 24.397403953091587 24.70309128305966 24.733369513099397 24.71201368685081 24.47296922543516 23.297674531046052 24.177994637090613 24.196901004811462 22.693691010164642 24.65463478117548 24.313811270577716 25.27420891718061 24.427800174782767 25.23016941841274 24.29911973152545 24.515992827148885 22.75049782945333 23.95533042323229 25.322200123254962 25.47733751564361 24.96929124026363 24.523448150592948 24.57946420246042 24.348643410248307 24.039397097926717 24.92870140228461 24.0 21.0 22.0 19.0 23.0 31.0 20.0 33.0 25.0 31.0 25.0 21.0 32.0 24.0 18.0 26.0 32.0 31.0 34.0 23.0 18.0 19.0 26.0 31.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.30568732996807313 0.24821307898992373 0.31935043564889154 GO:0019277 UDP-N-acetylgalactosamine biosynthetic process biological_process 20.204458223487546 21.07438807533645 19.83991904565635 19.343156225958936 17.13815992540787 20.4900760520887 19.752570343386267 21.89145956620139 NA 21.561587110193056 20.93320324687824 21.2632194705928 21.221809136533643 21.94703170608597 18.152928631924507 20.217859386712693 17.51276864171228 20.945258504133026 21.92303541458444 20.682898611964603 20.07499133520716 19.974783000277654 19.737324896333686 21.80469148754927 18.757207039506675 20.192877946383373 1.0 4.0 1.0 6.0 2.0 8.0 NA 6.0 3.0 7.0 3.0 7.0 4.0 6.0 1.0 9.0 8.0 8.0 3.0 4.0 2.0 12.0 2.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8699298518489051 0.022774727854040278 0.04131229703756143 GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway biological_process 25.973087250605932 26.074530074945105 25.351693337961073 NA 17.096546732738172 20.349868708970522 25.52187010311821 25.940467383012518 26.61458684238824 27.27651675572433 25.91617814962833 26.707042299053068 26.41941183771133 25.286255876718613 26.37033591195292 24.95226549346075 25.73471129697297 26.027320062720555 26.202549346238484 26.252692701496354 26.111955336582646 25.414121153396135 26.58232468746613 25.75893711085575 25.594113068514954 26.792728801170124 23.0 NA 1.0 1.0 31.0 30.0 58.0 41.0 46.0 36.0 50.0 23.0 37.0 19.0 40.0 31.0 46.0 41.0 39.0 24.0 49.0 27.0 44.0 36.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.1014428243391734 1.0 1.0 GO:0019294 keto-3-deoxy-D-manno-octulosonic acid biosynthetic process biological_process 23.03844185706533 21.089668481045493 18.556163236471747 NA NA NA 22.79783979936592 21.169928079425077 22.78776858073175 21.792464683760503 23.09145279705276 21.25426662975604 23.64896538721392 20.847339052610366 22.381922248127427 18.41148212746377 22.96216576505755 20.316105459774274 24.44868363123128 22.527649052624092 21.56697126892406 18.376540291542693 22.635474536503853 20.694277394368225 23.467634871790715 21.06859322850778 1.0 NA NA NA 11.0 5.0 11.0 5.0 10.0 4.0 19.0 4.0 12.0 2.0 11.0 4.0 15.0 14.0 7.0 1.0 17.0 3.0 16.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.9487733760198367 0.0019457736937391486 0.005456911392778556 GO:0019318 hexose metabolic process biological_process 30.269898974856535 30.82763802620592 30.72986564068902 30.274399773546147 30.713823387695776 30.74948512136348 30.181001810597948 31.09289792178321 29.408519694789828 30.905393105497964 29.97965582800013 30.96688855702961 29.83946330734085 30.25893051068594 30.42059577793236 31.09192212745642 29.908135971182052 30.837792262719912 30.911758048427025 31.05419795276926 30.6986010510746 31.01456071060801 29.6220878115624 30.435161917480563 29.91291311371478 30.911923223849683 273.0 128.0 239.0 181.0 344.0 302.0 353.0 323.0 363.0 342.0 356.0 181.0 421.0 292.0 337.0 258.0 531.0 383.0 333.0 232.0 349.0 271.0 309.0 355.0 6.0 5.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 7.0 5.0 5.0 6.0 6.0 6.0 5.0 7.0 5.0 5.0 5.0 5.0 7.0 6.0 5.0 -0.5577390513493867 0.0014961642897455532 0.004424675435076897 GO:0019320 hexose catabolic process biological_process 23.8753934195564 23.974264053832144 24.65963729598052 23.48249941253105 24.43658010447093 24.80976107263407 23.876466498938772 24.283863579607115 22.104256470061244 22.570352283837515 23.629008564359946 23.98305268408789 23.74436629835192 23.010729949412045 24.476760122857627 24.9163016571544 23.609308249517056 22.627691495463985 25.17172852155403 23.921944035435697 22.165561095052112 23.961959540260768 22.215833185750324 24.449894137134226 22.255767836072827 23.47468939896255 28.0 15.0 28.0 18.0 22.0 20.0 10.0 20.0 19.0 20.0 25.0 10.0 38.0 34.0 27.0 13.0 32.0 24.0 16.0 22.0 11.0 24.0 12.0 23.0 3.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 1.0 2.0 2.0 2.0 1.0 3.0 2.0 2.0 3.0 2.0 3.0 3.0 2.0 -0.0988706342757446 0.5253727863737021 0.6008633207515945 GO:0019350 teichoic acid biosynthetic process biological_process 21.669606698217493 24.71131743251416 23.79887273102695 24.61866661091291 22.80107957713856 24.945647029960714 19.960203096262322 25.39501982185565 18.843086778671857 24.393973394731173 18.951441742344134 23.959329903317517 21.360934938086945 24.99256723073976 21.81857390421575 24.914965419829677 19.920353453794466 24.27650931346621 21.344473143376185 24.983124408307336 21.45051269131451 24.405217488664388 16.369519027760624 24.50842522672223 21.57907436409725 24.54587820564931 19.0 25.0 10.0 20.0 4.0 35.0 2.0 21.0 3.0 19.0 5.0 26.0 10.0 28.0 3.0 25.0 8.0 24.0 6.0 23.0 1.0 29.0 6.0 25.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 -3.041710734296668 3.225641456243767e-05 0.0005099643033035255 GO:0019354 siroheme biosynthetic process biological_process 20.342696166924146 21.161043882986974 17.445181226146953 NA NA NA 18.38464041208457 20.466915792891378 19.883226097580792 22.29168443267292 17.183996932769915 21.534674144965358 21.91854358174817 20.47845625163955 16.52545470837626 20.022459842313488 19.779072922528254 19.850909277962284 20.583833807005185 21.33005893439346 20.10238316623237 18.63508542041588 21.157853996577085 19.490918138577076 21.514265748371415 22.64856772011838 2.0 NA NA NA 3.0 5.0 5.0 9.0 3.0 7.0 11.0 5.0 1.0 2.0 6.0 3.0 6.0 10.0 4.0 2.0 12.0 4.0 11.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8183477160628279 0.18091609383032226 0.24621950392610922 GO:0019358 nicotinate nucleotide salvage biological_process 22.77269161419877 24.294663628852486 23.24797275136959 24.044736192031845 23.50382659471228 24.02296846080534 22.78040575727777 24.50498286086216 21.644427317158627 23.84234506819644 23.17521040170451 24.258356612091752 23.131599380130325 24.215569315118127 22.95227070391841 24.788712920256003 22.53889122991412 23.84045639255847 21.821794467939 24.617175076593853 21.787961203398517 23.85941377563697 21.487235918654147 25.000729013451018 23.325515062235322 23.901353838948086 13.0 17.0 17.0 18.0 10.0 18.0 11.0 18.0 11.0 18.0 17.0 20.0 17.0 25.0 10.0 17.0 14.0 22.0 10.0 19.0 11.0 23.0 14.0 19.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.5219720146537163 3.225641456243767e-05 0.0005099643033035255 GO:0019359 nicotinamide nucleotide biosynthetic process biological_process 28.400368945619828 29.55651737370418 29.046989911052343 28.90870344704598 28.693108006676567 29.661602266116986 27.765554869935695 29.786988626189427 27.21505875279364 29.390198154447432 28.26254087876153 29.325848068087197 28.07007508305993 28.89828883640987 29.23373428069794 29.95741068709025 27.81941702187633 30.156449544128147 29.176890120445428 29.77184480123505 28.18735908487514 29.47313299082241 27.620899409772 29.518116003066105 28.10143560507045 29.272773964424363 107.0 107.0 132.0 144.0 116.0 182.0 129.0 154.0 133.0 145.0 120.0 109.0 167.0 143.0 113.0 150.0 200.0 162.0 144.0 141.0 131.0 136.0 122.0 139.0 3.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 3.0 3.0 2.0 3.0 3.0 3.0 -1.1561484280843537 0.0001386794054294884 0.0007006959432226783 GO:0019362 pyridine nucleotide metabolic process biological_process 29.51336766118012 30.670669283165346 30.128780513810398 30.071255285883602 29.8266456735149 30.754481161519863 28.908807581179037 30.905393527446623 28.35019312222289 30.496471362334646 29.380703211414318 30.45435760532771 29.223686353828178 30.08203075712929 30.3014415518995 31.05366752267432 28.942539815685876 31.204211478199053 30.290818417144784 30.89528197950277 29.2983574543366 30.574410662062864 28.73731446351345 30.67209791065805 29.24706489394705 30.410604097830788 284.0 312.0 347.0 370.0 299.0 474.0 326.0 417.0 332.0 400.0 340.0 336.0 437.0 409.0 286.0 390.0 515.0 452.0 357.0 381.0 335.0 399.0 328.0 375.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.1573016219852263 0.0001386794054294884 0.0007006959432226783 GO:0019363 pyridine nucleotide biosynthetic process biological_process 28.45757810431105 29.629824827036227 29.097904296761964 29.004533300656018 28.770098208951588 29.718387005377693 27.85389553740497 29.859304278249674 27.274528426071182 29.45059469257595 28.34501039283841 29.40942703247881 28.16123054810113 29.00647701210713 29.270358753937305 30.035477816419807 27.891805064911136 30.1922184994363 29.194407166682357 29.850654256870165 28.2211421490202 29.530887349689284 27.661419893857346 29.63890520788404 28.20308834695363 29.340844633079165 133.0 141.0 166.0 180.0 136.0 218.0 151.0 190.0 155.0 181.0 154.0 149.0 201.0 193.0 133.0 184.0 228.0 206.0 164.0 179.0 153.0 182.0 150.0 177.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.172246722725177 0.0001386794054294884 0.0007006959432226783 GO:0019400 alditol metabolic process biological_process 26.605168967041067 25.143386650324906 24.512522212677588 24.34779136473641 24.187627490226497 24.310774053051468 26.208088367972675 24.753615235296174 26.68586383646189 24.503303454096127 26.994724688107386 26.818205717822853 27.30404033505444 25.474745096479715 26.28092925311153 24.85380836486053 24.37078028470483 24.27911012922029 28.315577009018842 25.43321030365912 27.32159801392044 24.671271474023012 25.252343827090673 24.980319358255077 25.633260522129397 24.825925981451746 25.0 23.0 21.0 24.0 52.0 26.0 62.0 15.0 59.0 50.0 63.0 21.0 79.0 18.0 36.0 26.0 90.0 58.0 47.0 22.0 45.0 16.0 53.0 33.0 2.0 2.0 3.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.4617823167161603 0.03766692222862868 0.06276144050911694 GO:0019430 removal of superoxide radicals biological_process 19.977190204487425 22.532051318589147 19.606015882194406 22.90007019751261 18.850694370832333 20.356227657324627 19.79579938610734 24.088557971487894 17.702005437728552 22.19017373232976 17.680097096676118 22.66977506035171 NA 23.255697110783025 20.54438832238748 21.983563545554947 20.21929571054689 22.697739166162556 21.55573991167613 21.593206916727013 20.14723540683956 20.009803009017023 19.93106474127725 22.036861961478266 19.52755108137669 22.20205467260447 4.0 6.0 1.0 6.0 2.0 12.0 2.0 8.0 2.0 10.0 NA 8.0 6.0 8.0 5.0 13.0 5.0 6.0 2.0 4.0 3.0 8.0 4.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.5548611141017226 0.00022184668066321214 0.0009959160340564342 GO:0019438 aromatic compound biosynthetic process biological_process 32.54652920521108 33.319341682436736 32.671765004913865 32.72980770452579 32.3174810955372 33.23351608830505 32.235033478962286 33.48669292627398 32.13019145272873 33.250398449038485 32.729330043153 33.22807820544656 32.7246253148634 32.90773316347321 32.87847218940928 33.67900667694137 32.09625757529595 33.708496089796704 33.10866004552451 33.487188063109805 32.509419990178074 33.17392378519676 32.27777127738814 33.44550590726457 32.491852885971184 33.19077863988822 3375.0 3424.0 3244.0 4036.0 3702.0 5343.0 4112.0 4999.0 4272.0 5022.0 4665.0 3856.0 4558.0 5069.0 3658.0 5177.0 5780.0 5612.0 4221.0 4240.0 4357.0 4712.0 4461.0 5127.0 9.0 10.0 7.0 10.0 8.0 9.0 8.0 8.0 9.0 10.0 9.0 10.0 8.0 10.0 8.0 10.0 9.0 9.0 8.0 8.0 9.0 10.0 9.0 10.0 -0.7728124772256564 6.784570247173055e-05 0.0005498145239267514 GO:0019439 aromatic compound catabolic process biological_process 29.716697702664607 29.8390342853914 29.6145625830433 29.29218858878777 29.364031254489017 29.82899927193665 29.32002883964376 30.119298345100606 29.607449809804184 29.63012379204267 29.91576020457527 29.68095444942353 29.69655931747453 29.198932669696784 30.262877312374147 30.1112804332744 29.123063369534226 30.259998899687144 30.04019185084748 30.390014307430945 28.83665540550416 29.763234654347208 30.22985051575861 29.698508356581545 29.879783924426626 29.582902561268643 236.0 223.0 247.0 275.0 317.0 368.0 405.0 315.0 410.0 325.0 385.0 244.0 437.0 292.0 287.0 294.0 485.0 459.0 309.0 265.0 365.0 254.0 371.0 304.0 4.0 4.0 4.0 3.0 5.0 4.0 5.0 5.0 4.0 4.0 5.0 5.0 4.0 4.0 4.0 4.0 5.0 5.0 5.0 4.0 4.0 2.0 5.0 4.0 -0.12233658272679193 0.4884223166225936 0.5675521891480417 GO:0019510 S-adenosylhomocysteine catabolic process biological_process 20.522233363289004 21.640528913645934 19.94113959091284 NA NA NA 18.640937888333887 22.033940519237067 19.98632754332611 22.579025723641504 19.832689277784635 21.979802435645546 21.38100739397645 20.940440126713533 19.41082690171566 21.017960072508718 19.53843142466959 21.741015139271145 20.73368818906923 20.970982217102254 20.06805760065568 20.257466593257508 22.17818769522719 20.97650610857601 20.41636491713456 22.2488155855243 5.0 NA NA NA 2.0 10.0 6.0 13.0 5.0 10.0 7.0 7.0 1.0 8.0 3.0 9.0 6.0 8.0 4.0 3.0 8.0 6.0 6.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1182955503569296 0.004851753319766388 0.011381556659903107 GO:0019512 lactose catabolic process via tagatose-6-phosphate biological_process 24.002323597687067 24.919842472177816 25.27449484529668 24.99165106471495 25.179482401291466 25.339841145760694 23.70810815339182 25.732289148777905 19.801872474524533 24.20771980334291 21.62585065103897 24.968470000212804 23.794359841325086 24.942681877374266 25.340865265459872 25.816684715190224 22.58831015018093 24.167807025416703 24.917613798187407 23.898832065380248 22.377764033504487 24.88000408118951 20.519048760613693 24.15352505257185 21.61621718297809 24.374000480032617 40.0 34.0 44.0 27.0 19.0 42.0 3.0 34.0 12.0 37.0 20.0 27.0 38.0 55.0 17.0 35.0 36.0 29.0 16.0 32.0 6.0 30.0 14.0 33.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9175188744907494 0.02824036873330045 0.04901805310036017 GO:0019521 D-gluconate metabolic process biological_process 25.26803504358828 26.603856104508143 26.202510986235488 26.57647246294293 26.19664787627061 26.827330709366517 24.107195971404963 27.005083179066144 23.692375111531142 26.409253316195432 23.929985013917022 26.427307404020446 24.80338066292583 26.72156966910079 25.189746456658305 26.378197784903 24.19773995921857 25.621627962953372 26.54594624678773 27.08539095823343 25.801846716309953 26.81929205209498 24.14002088990499 26.338144643726398 24.3489503174805 26.50922401067333 24.0 24.0 33.0 34.0 19.0 34.0 20.0 26.0 21.0 31.0 25.0 26.0 30.0 28.0 22.0 25.0 36.0 37.0 37.0 27.0 22.0 31.0 27.0 22.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.3358210609198622 0.0002755038114342687 0.0011655212090507369 GO:0019538 protein metabolic process biological_process 31.00947231193809 30.342627294412164 30.03739340258771 29.66804453399654 29.76947427117637 30.39544533242569 30.5576824447047 30.30758238824141 31.134530142545557 29.95449990176881 31.183702429366196 30.566044957354013 31.186554452630173 30.33507470432949 31.347156757602033 30.568692179431487 30.59424358735975 30.066374094746408 31.72466691832032 30.69720914374113 30.98846654208529 30.12551576982924 31.53538596263625 30.629617457566557 30.866242407680673 30.45290290774475 621.0 357.0 436.0 676.0 705.0 595.0 955.0 635.0 891.0 716.0 908.0 464.0 1080.0 577.0 684.0 531.0 1107.0 956.0 779.0 446.0 913.0 532.0 775.0 728.0 6.0 4.0 5.0 5.0 6.0 5.0 6.0 6.0 6.0 6.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 6.0 6.0 6.0 0.666845017525926 0.009374768459434895 0.01937038251220985 GO:0019547 arginine catabolic process to ornithine biological_process 25.85247801101304 25.32374331961203 26.851270078000326 24.48053137690885 26.840185656373528 25.881515835631966 24.84163094530613 25.73472341859209 25.20604478317021 24.86183554499104 25.482766943574706 25.762306843840822 25.244629556647958 24.894692276854762 26.22607622505573 25.224582107320213 24.73362032756492 25.4242775394771 26.284712312724448 25.00110616194653 26.5050452908787 26.596099824066442 23.166094181521085 21.63889939301935 25.16454422317544 24.375644955917654 9.0 5.0 8.0 12.0 10.0 11.0 9.0 7.0 11.0 8.0 6.0 7.0 10.0 8.0 4.0 11.0 13.0 7.0 8.0 11.0 9.0 6.0 10.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.5287346914010094 0.27265646879500405 0.34545713000625894 GO:0019556 histidine catabolic process to glutamate and formamide biological_process 26.735192465968915 24.32532037760989 25.503108355026182 24.261752894870032 25.01792471242503 21.110295521138664 26.553885285015372 24.53085272425409 27.13482251169409 23.436300408737413 27.22652346381043 24.847153169781237 26.91859223953291 23.352459245420594 27.090059043237602 21.35275565986682 26.203609360628857 18.74776968490549 26.419229339259648 26.3780509250004 24.6537202663764 24.62482597422139 27.81499980653689 NA 27.224528603335344 23.94652682825186 11.0 9.0 14.0 4.0 26.0 14.0 41.0 11.0 43.0 13.0 40.0 10.0 43.0 7.0 26.0 2.0 29.0 37.0 20.0 11.0 29.0 NA 37.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.4098720883590232 0.00017383318364122836 0.0008236168584623857 GO:0019557 histidine catabolic process to glutamate and formate biological_process 26.854331631732496 24.46895945333814 25.766840005637864 24.39203279040516 25.32964949437089 21.740405627398907 26.595880728381424 24.61974273736969 27.242460043442946 23.57365480919064 27.320644825677928 24.992248347819718 27.032960946206625 23.417171319143968 27.198643943744827 22.016108648507558 26.32720008400755 19.212220492707566 26.48837351486091 26.504919992834033 24.863692894212285 24.69708421176786 27.96913196165549 NA 27.305443078772697 24.23885113971093 15.0 13.0 19.0 10.0 32.0 18.0 52.0 14.0 53.0 16.0 50.0 11.0 54.0 9.0 34.0 3.0 38.0 46.0 27.0 16.0 39.0 NA 46.0 16.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.3853721783943556 0.00022184668066321214 0.0009959160340564342 GO:0019563 glycerol catabolic process biological_process 25.23365744360076 22.37228896551383 22.374773264320826 21.729977553507663 21.181693742133007 20.951731606937575 24.605035800004515 20.123171915573057 25.262303248553337 17.23855670669803 25.44831162180107 25.240727657781488 25.94720484930362 20.603892960581945 24.78105665246161 19.08583486638594 22.01891302912467 20.782589447863185 27.241896967447328 23.33793951936857 25.995569283767576 19.39304320344312 23.912464522900944 16.886367989739707 23.82810672284186 21.668204934798737 8.0 6.0 6.0 5.0 14.0 6.0 20.0 2.0 16.0 18.0 22.0 7.0 24.0 2.0 9.0 5.0 33.0 20.0 18.0 3.0 15.0 1.0 14.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 1.0 NA NA NA NA NA NA 2.861368478086927 0.0005320055051392492 0.0019244720881558927 GO:0019637 organophosphate metabolic process biological_process 35.061803719881816 35.86513870250825 35.23872080395036 35.206925688827745 34.87167908810927 35.79321984050079 34.68565998309378 36.04351485208654 34.597615748922 35.79144925163228 35.20606870348715 35.762268959176204 35.16886353994434 35.383977053430506 35.48511005201658 36.242921436183465 34.622795946795804 36.32215832615822 35.62967508778812 36.02911026707647 35.05033007587237 35.74354456984028 34.74140758557457 35.94412962075361 35.00520773296977 35.741245332409065 17073.0 16860.0 16689.0 20416.0 18969.0 27168.0 21148.0 25098.0 21716.0 25139.0 23592.0 19091.0 23660.0 25326.0 19004.0 26056.0 29077.0 27917.0 21804.0 21678.0 22378.0 23305.0 22864.0 25611.0 14.0 15.0 14.0 14.0 18.0 14.0 16.0 16.0 18.0 16.0 16.0 16.0 15.0 15.0 17.0 15.0 18.0 15.0 17.0 13.0 17.0 15.0 18.0 16.0 -0.8033349826264313 0.00010962068302139599 0.000648372570666835 GO:0019682 glyceraldehyde-3-phosphate metabolic process biological_process 26.476366187265306 26.86638559209707 26.089220917336675 25.807013089359703 25.078302060705845 25.663941473193663 25.948415771520573 27.04708175576883 26.793170580593987 27.68610995936303 26.18911120376337 27.27971887873879 26.74514319481622 26.534732026461395 26.777439902757624 26.28599441267573 26.13561928965128 26.544448306654417 27.270167994711684 27.22531314813689 26.64775441887436 26.598202370047716 26.859165901505104 26.754361859916855 25.97660847189774 27.502217653495546 44.0 32.0 20.0 20.0 51.0 64.0 79.0 77.0 65.0 73.0 80.0 55.0 76.0 50.0 60.0 56.0 100.0 85.0 64.0 50.0 74.0 61.0 64.0 64.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.3900194048317651 0.24821307898992373 0.31935043564889154 GO:0019692 deoxyribose phosphate metabolic process biological_process 24.938648449677014 24.49551701823616 23.12249913802145 24.351249432330672 24.47971856992493 23.920781662238163 23.923888305850234 24.825969212786635 24.602133360923123 24.110997401911828 25.19300237063595 24.208949010217037 26.044612162545143 24.98281558008874 23.48726791623621 24.692681998329693 24.07536238329617 24.221224759284482 26.16805011890068 25.1278829868546 24.601924297589 23.67991120273933 25.229529588687647 24.814611098741945 25.051167131109324 24.243157063013662 51.0 62.0 36.0 55.0 61.0 50.0 55.0 56.0 74.0 93.0 115.0 83.0 36.0 71.0 41.0 74.0 87.0 92.0 49.0 39.0 88.0 65.0 96.0 76.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 0.4431314314408539 0.4884223166225936 0.5675521891480417 GO:0019693 ribose phosphate metabolic process biological_process 32.099859850708626 32.872780621818855 32.234398211077014 32.21071016916387 31.87968628983511 32.80173164571139 31.723515864440003 33.05358950267552 31.682618589585754 32.79249434802542 32.265590444174464 32.76545688349297 32.208369540550784 32.39909607933993 32.51278053704609 33.25402899896357 31.67032231521374 33.32297604514656 32.657215005057076 33.03169645389203 32.078722873893305 32.75595676004888 31.79768991852229 32.952146636502015 32.07478739046946 32.7592949250968 2165.0 2130.0 2128.0 2588.0 2420.0 3482.0 2700.0 3198.0 2758.0 3178.0 2960.0 2399.0 3051.0 3240.0 2432.0 3316.0 3706.0 3564.0 2789.0 2767.0 2826.0 2957.0 2894.0 3253.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 5.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.772920771110229 0.0001386794054294884 0.0007006959432226783 GO:0019725 cellular homeostasis biological_process 27.1910250056187 27.469878655935307 26.20525554792586 27.710783364993638 26.873410022997426 27.44066243920889 28.01248446158031 27.65735955515591 26.49793289062009 27.31475058321533 26.83607563431473 26.091780704653953 27.854598415203746 27.845700508209998 26.44127173067316 27.76389637477094 26.337264238157072 27.198899064268627 27.918258450973173 27.99698666821795 26.61931403383865 27.44646166191578 27.83871286171021 27.36292067422113 27.035892122416488 26.977588843168174 63.0 69.0 43.0 79.0 64.0 111.0 64.0 94.0 67.0 84.0 69.0 79.0 78.0 100.0 62.0 98.0 88.0 111.0 51.0 77.0 68.0 105.0 63.0 83.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 -0.2788536503166057 0.27265646879500405 0.34545713000625894 GO:0019748 secondary metabolic process biological_process 22.65125355816544 26.2127544880934 22.929028808669162 26.3887442409423 24.482529822207546 25.12212334648889 21.88576247909437 27.26021239438817 19.58070333076288 26.23888307590003 17.317685049081028 24.21743392120291 22.094939083691173 26.596285085945677 23.461142552992953 25.755636700682306 22.658851228685645 26.04154319479381 23.190642661981048 26.707951572276066 22.60678691742686 26.114477038412858 19.66237873080127 26.523903702475234 21.678989119993343 25.37446996022547 15.0 29.0 14.0 23.0 9.0 24.0 3.0 24.0 3.0 26.0 2.0 23.0 18.0 22.0 15.0 32.0 21.0 26.0 17.0 20.0 3.0 24.0 9.0 21.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 -3.561500929927959 4.146041132679973e-05 0.0005099643033035255 GO:0019751 polyol metabolic process biological_process 27.246115862212505 25.618413659454287 24.97139259086433 24.56553629294204 24.35689439023932 24.485567665544014 26.79946484933567 25.263669757760372 27.20909764227913 25.31425518316949 27.5131447593512 27.326398961891442 27.947149445816606 26.127157300589193 26.79926223376317 25.08281075103161 25.22853634402361 24.928924076542906 29.098339901165648 25.938609637142676 27.888820272081073 24.93677056171649 26.235613629409233 25.13654667955213 26.16346500497309 25.43767927051023 37.0 29.0 27.0 32.0 88.0 38.0 98.0 22.0 99.0 85.0 105.0 35.0 109.0 26.0 62.0 37.0 160.0 90.0 88.0 30.0 81.0 23.0 82.0 51.0 3.0 2.0 2.0 3.0 5.0 3.0 4.0 3.0 5.0 4.0 4.0 4.0 3.0 3.0 5.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 4.0 1.6277022027582184 0.017926339076638688 0.03379466943753034 GO:0019752 carboxylic acid metabolic process biological_process 32.97335966109211 32.96523558842705 32.552045731378385 32.14324441595129 32.313791388999405 32.77019395885431 32.685943034326954 32.92210641718443 32.83942580757944 32.765308960917466 33.243985006951355 33.20709268564836 33.133992494456855 32.607745188074745 33.33611297433886 33.297474326003986 32.4849821599313 33.39815257766834 33.570685720716526 33.25017357698005 32.56218399408993 32.714369763574204 33.26586848030988 33.213368737021234 33.0803467396193 32.81526581052339 3223.0 3577.0 3828.0 4823.0 3844.0 5941.0 4441.0 5786.0 5195.0 6055.0 5464.0 4566.0 5338.0 6042.0 3722.0 6508.0 6450.0 6309.0 4767.0 4943.0 5281.0 5776.0 4778.0 5846.0 9.0 8.0 8.0 8.0 10.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 10.0 9.0 10.0 9.0 10.0 9.0 0.008124072665061988 0.8173613313851769 0.8543274217493305 GO:0019829 cation-transporting ATPase activity molecular_function 27.571356371438107 28.51046108301193 27.32889967039303 27.896514922050446 26.97321117011018 28.237190431055414 27.234912378263893 28.452202303025388 27.47857281380897 28.43098721423041 27.69258097547643 28.55008478849369 27.667119040829807 28.250770450587613 27.291225088792995 28.919670233820852 27.439059857651852 28.71008465077725 28.068993881959038 28.58289455951835 28.013892313878106 28.354043327320213 27.62841374659245 28.74406601461572 27.656747887593607 28.710022050277253 131.0 131.0 114.0 155.0 138.0 170.0 184.0 197.0 164.0 189.0 174.0 150.0 180.0 183.0 137.0 162.0 166.0 211.0 160.0 175.0 163.0 158.0 174.0 235.0 7.0 5.0 4.0 5.0 5.0 5.0 6.0 7.0 6.0 7.0 6.0 6.0 7.0 6.0 7.0 6.0 6.0 6.0 4.0 6.0 6.0 5.0 7.0 6.0 -0.9391047115738225 5.312128159411724e-05 0.0005099643033035255 GO:0019842 vitamin binding molecular_function 28.88872675395585 27.679578088818776 26.63799145365829 25.622766768562197 25.127730990680128 25.379009315688247 29.124475042804065 27.57027008598165 29.590040795602864 28.41697887150303 29.44143844467863 27.88063129454415 29.09867596008681 27.221436475442772 29.574814036579546 27.347653970895546 29.221665175710275 27.545779313646435 28.901000057341555 28.165704724921646 27.27993646856378 27.148754007341328 28.97024899898222 27.119785417991928 28.925885363584808 29.062447202569647 78.0 56.0 47.0 57.0 186.0 125.0 208.0 129.0 233.0 142.0 198.0 113.0 239.0 132.0 175.0 119.0 251.0 196.0 129.0 101.0 185.0 124.0 213.0 129.0 5.0 3.0 4.0 3.0 5.0 5.0 4.0 6.0 4.0 7.0 6.0 5.0 6.0 6.0 6.0 6.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 7.0 1.209148665137075 0.02092133533779403 0.038284203081476474 GO:0019843 rRNA binding molecular_function 30.964621138606077 31.29052882315537 30.73908606640493 30.585133747107932 30.673878804088048 31.261452979197895 30.31744335026827 31.309148219369 30.976642016602067 31.110165978133804 30.891537109492546 31.39954114122782 31.059250067281088 31.242287614906587 31.37773125637613 31.54639547351729 30.57280507279153 31.237759930248213 31.50631341566165 31.398576049748026 30.974292938139076 31.317640739770642 31.342794842461576 31.569575827756942 30.653700793196496 31.28667727967861 516.0 268.0 372.0 560.0 524.0 506.0 729.0 446.0 630.0 514.0 548.0 348.0 856.0 517.0 545.0 451.0 769.0 634.0 606.0 416.0 657.0 425.0 537.0 540.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.32590768454929275 0.024343383653741054 0.04309296851045225 GO:0019856 pyrimidine nucleobase biosynthetic process biological_process 26.82328116477638 26.658432977210143 26.569284754572625 25.326775249288392 24.62561625797391 25.755549571795047 26.32593019118599 26.472726716305715 26.58406880287169 27.15938685783976 27.43752750581658 27.76035409720111 27.46328048496551 26.67408251920118 26.496069098910446 26.09638497898881 26.48495948501717 26.22671043442676 27.027889984202968 26.5693779627743 27.265023592372646 26.470579998023855 27.300205687853374 27.03890677674863 26.516264484817253 26.76633462484562 47.0 34.0 20.0 37.0 62.0 65.0 89.0 80.0 66.0 76.0 72.0 54.0 88.0 48.0 74.0 67.0 85.0 75.0 62.0 49.0 79.0 60.0 78.0 69.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 0.16484818756623554 0.3556110610952391 0.43337630976650365 GO:0019877 diaminopimelate biosynthetic process biological_process 23.784644392486978 25.193061124810036 23.39019345479131 23.891244602036195 23.00196762285039 24.247482397843005 23.429569848989548 25.533757358658605 21.6648583833492 25.613370773847972 24.498436029428433 25.316790465992533 24.7034592609728 25.26683630923222 22.220951898036343 24.91647510544293 23.85230268015336 26.129643078748533 24.286578115338703 24.92666086504462 23.8699021000165 24.34757799490445 24.380423942745004 24.864367209564342 23.351757704668945 25.68349071326353 21.0 22.0 16.0 22.0 16.0 47.0 11.0 48.0 15.0 45.0 29.0 38.0 14.0 40.0 21.0 41.0 33.0 37.0 27.0 38.0 22.0 33.0 21.0 39.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.408416732323058 0.00042856814449695465 0.0016457016748683058 GO:0019897 extrinsic component of plasma membrane cellular_component 20.626673700671443 22.529647735171928 18.042634453488752 21.579715750083565 20.435853415985306 23.05449874600841 20.73796978458854 23.321893636867408 18.77510935475579 21.416728105066507 20.30275590218651 21.66845902949823 21.949545436608528 22.39435695314753 21.70053880492004 22.561120831228965 17.574921738280374 21.736533481155057 21.333498352857546 21.437806306170536 19.933987313036358 22.880576808433545 20.561876480328323 23.138462401062213 20.42019002514637 23.133477585083664 3.0 12.0 6.0 23.0 5.0 23.0 3.0 13.0 5.0 11.0 8.0 13.0 3.0 23.0 2.0 15.0 10.0 11.0 6.0 22.0 6.0 23.0 6.0 20.0 NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA -1.9029740345004846 0.0002755038114342687 0.0011655212090507369 GO:0019899 enzyme binding molecular_function 22.7758248068201 22.43848776415417 20.733037138051195 19.86388609347461 20.743795222640003 18.81062751803604 23.289817076264228 22.603700403372354 22.654731616013645 23.752519358519816 23.165994155724462 23.358313345496306 22.773879505116266 22.581077996334034 22.29255322013649 21.98291890017945 23.66005087505489 22.410616186471515 23.833730972936568 23.08208903773334 21.038651183028325 20.93459792496544 18.91100725398637 21.480762246979985 23.65903605196973 22.4499847993016 4.0 3.0 1.0 3.0 3.0 6.0 4.0 9.0 9.0 9.0 6.0 10.0 1.0 6.0 5.0 8.0 15.0 10.0 4.0 3.0 3.0 10.0 5.0 7.0 1.0 3.0 1.0 2.0 1.0 3.0 3.0 2.0 3.0 3.0 2.0 3.0 1.0 3.0 3.0 3.0 3.0 4.0 1.0 2.0 1.0 4.0 2.0 2.0 0.33733704266592923 0.4529203011037244 0.5347630423627702 GO:0020037 heme binding molecular_function 24.25738756172501 21.634327554668122 22.967410511278896 NA 20.93980053680536 19.969534833522488 23.62505177881413 19.99436453506821 23.81241820053685 21.081780614242767 23.178148236849648 21.95081137946118 25.108289117745407 19.301490000246154 24.78579198739269 NA 22.62737360222053 NA 24.211359551138802 19.561922619793144 24.074281522339557 16.482770436332338 23.8377743373343 18.799996028615414 26.053011926463874 24.178327650218762 7.0 NA 8.0 6.0 16.0 6.0 15.0 4.0 11.0 11.0 17.0 3.0 13.0 NA 9.0 NA 28.0 5.0 13.0 1.0 13.0 3.0 24.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.623060007056889 0.0017663366484100085 0.005134928866041682 GO:0022402 cell cycle process biological_process 26.93875400971289 28.04893140883777 27.538227329501556 27.880332136440806 27.350625148147817 27.22428037775764 25.746572232333914 28.100501795197786 26.026452763453324 28.071743855528908 25.948460449489993 28.252057369767922 26.51332760140166 28.026213754553037 27.55194149746984 28.35147518840361 26.50083068947001 27.813808877219238 27.470116630595843 28.503860617176148 27.370178272380127 27.74998401466763 27.110092753409724 28.252548159542307 26.523067695655303 27.959212168563088 117.0 109.0 98.0 98.0 71.0 149.0 57.0 147.0 82.0 122.0 85.0 119.0 138.0 172.0 67.0 142.0 138.0 165.0 100.0 138.0 83.0 160.0 96.0 140.0 5.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 4.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 -1.1101773991248791 0.00010962068302139599 0.000648372570666835 GO:0022607 cellular component assembly biological_process 27.372391021501212 28.139705623293143 27.619656422943216 27.745538525497032 27.327024215353717 27.408668824538196 26.136687891116274 28.26138724078424 27.035604254677235 28.17509420315316 27.029024518134538 28.352557586084213 27.401980023960647 28.13311845688315 27.81862932732848 28.41999332619511 26.96939851119421 28.089551506002913 27.743904662448806 28.533095302459365 27.598858507703266 27.718572834742666 27.979975929771427 28.393206745585466 26.88332933374201 28.045308174624015 128.0 86.0 95.0 116.0 80.0 143.0 89.0 132.0 132.0 142.0 129.0 119.0 152.0 159.0 99.0 161.0 178.0 163.0 124.0 115.0 129.0 141.0 105.0 126.0 6.0 3.0 4.0 4.0 5.0 4.0 3.0 5.0 5.0 5.0 5.0 4.0 4.0 5.0 5.0 3.0 4.0 4.0 5.0 4.0 5.0 3.0 5.0 5.0 -0.7673146017919308 0.00034415785384659113 0.0013990521224773477 GO:0022613 ribonucleoprotein complex biogenesis biological_process 25.45781140302744 26.10106012783341 24.977854814370346 25.88156132305944 24.399659786162356 25.63085678526854 25.08243245648945 26.32736470709081 25.525216285537105 25.98235147303937 25.310284846318297 26.44353334353313 25.06824416925012 25.771121664352002 25.67828519637457 26.07473948967513 24.816995122524705 26.053791113950343 26.90242150832377 26.56727759058372 24.93755924382891 26.006042596524768 25.827041802107054 26.316667543482623 25.136952432868362 25.843159863965568 60.0 63.0 44.0 68.0 33.0 83.0 40.0 65.0 48.0 74.0 50.0 57.0 51.0 72.0 40.0 71.0 58.0 90.0 53.0 64.0 37.0 78.0 48.0 75.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.6432487248059715 0.0009986863791802587 0.0031633517797384847 GO:0022618 ribonucleoprotein complex assembly biological_process 25.189101912067386 25.595042464427753 24.79502406577661 24.90569362782595 25.003727516913482 25.54341393756733 24.08704214492214 25.931788552669854 25.928514060951038 25.45976392090486 24.709284235334 25.52182426968223 25.19688510690318 25.29245513468628 25.900937208609022 25.935471942444728 24.07363947057448 26.011397107654144 24.664753825097794 25.86042194449746 24.843398416694487 25.36073959880984 26.39919229452757 25.512824747551303 24.4679935588724 25.41548110918182 14.0 6.0 13.0 33.0 14.0 12.0 22.0 11.0 25.0 15.0 22.0 14.0 25.0 15.0 18.0 16.0 26.0 18.0 19.0 13.0 28.0 13.0 16.0 15.0 1.0 1.0 2.0 2.0 3.0 1.0 2.0 1.0 2.0 1.0 2.0 2.0 1.0 1.0 2.0 1.0 1.0 2.0 1.0 2.0 3.0 2.0 2.0 1.0 -0.4059405523603665 0.02092133533779403 0.038284203081476474 GO:0022804 active transmembrane transporter activity molecular_function 29.71609059801311 30.684674888786912 29.576626400660142 30.09766199486051 29.251549917980288 30.412967912516518 29.323946407507922 30.67455698998787 29.55541038304829 30.625261775700242 29.85470086348409 30.762325113028 29.798104177837885 30.45184687389057 29.52633524059491 31.058544920466485 29.48067609714456 30.872654460376967 30.250377230882656 30.737385265502077 30.170569339312486 30.468131843285537 29.68113790092647 30.95667406805393 29.75975910829727 30.830944609726767 640.0 685.0 589.0 833.0 573.0 922.0 750.0 959.0 714.0 955.0 784.0 802.0 808.0 1035.0 596.0 884.0 775.0 1018.0 733.0 905.0 695.0 920.0 753.0 1094.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.9685842907738014 5.312128159411724e-05 0.0005099643033035255 GO:0022834 ligand-gated channel activity molecular_function 22.73208382752203 23.831843971492724 19.79217006619826 24.60576789982731 19.96913902434685 22.385583837823475 23.12385058898169 23.63453745770861 21.74790084914752 23.020697380576426 23.55498842631577 23.349891181753698 24.318880281897147 24.499019251225857 19.950346776166604 24.098095820898795 21.34437384450316 23.018259824941783 18.728898713716852 23.530808747657428 22.790396644434857 22.22940808680559 23.496906778392443 24.971760247964745 23.58145187134979 23.91688959186273 4.0 28.0 4.0 14.0 14.0 22.0 8.0 22.0 14.0 22.0 12.0 24.0 6.0 22.0 8.0 20.0 4.0 20.0 4.0 16.0 10.0 28.0 16.0 28.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.0997601439706948 0.02092133533779403 0.038284203081476474 GO:0022836 gated channel activity molecular_function 23.317046328243194 24.441640249734537 20.377132566919414 25.19686480110004 20.55410152506801 23.00264282932531 23.708813089702844 24.2478478936863 22.33286334986867 23.792503510236234 24.139950927036928 23.94318669916336 24.90384278261831 25.083981751947018 20.535309276887762 24.683058321619953 21.929336345224318 23.671982634866943 19.313861214438006 24.12428287380012 23.375359145156022 22.898699630645513 24.0818692791136 25.576478927647425 24.166414372070946 24.51507094720701 6.0 43.0 6.0 22.0 21.0 34.0 12.0 34.0 21.0 34.0 18.0 36.0 9.0 33.0 12.0 32.0 6.0 31.0 6.0 25.0 15.0 44.0 24.0 43.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 -1.1245939214913427 0.017926339076638688 0.03379466943753034 GO:0022857 transmembrane transporter activity molecular_function 31.187048221887192 32.12620483798481 31.012696328283443 31.56569900500083 30.75658651318892 31.83884369172831 30.78246298119657 32.11264823507103 30.992523715322534 32.03599788162565 31.363320895672594 32.2092423176691 31.35164955593068 31.956322351590327 31.092742328503377 32.51843041400515 30.98833250717801 32.273281471831424 31.626594196901216 32.16127212875162 31.58139987582023 31.868924548211588 31.119103445245948 32.45505804225407 31.26989337619477 32.24697775861518 1815.0 2218.0 1669.0 2520.0 1654.0 2966.0 2178.0 2915.0 2110.0 3020.0 2342.0 2546.0 2316.0 3359.0 1761.0 2766.0 2176.0 3100.0 2026.0 2760.0 2028.0 2987.0 2206.0 3309.0 19.0 18.0 15.0 17.0 18.0 17.0 18.0 17.0 19.0 19.0 19.0 17.0 20.0 18.0 18.0 19.0 21.0 20.0 18.0 18.0 18.0 19.0 20.0 19.0 -0.9391566160976161 5.312128159411724e-05 0.0005099643033035255 GO:0022869 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity molecular_function 20.501179522344025 20.73720803371309 21.604188612027922 19.108170303082094 21.260882456276104 20.363563945176693 18.960562209932068 17.179114425885633 NA 17.49054054961227 18.9026426216678 20.87296629784381 21.030266306750995 19.927798591121878 21.198350919570977 23.533783340424584 18.990601057651 17.610114742099267 19.66242361108456 18.06168563792073 21.228868750176453 18.610896245266712 18.711534613614226 20.876751466346832 19.678072689984518 19.72517948501178 4.0 2.0 4.0 3.0 2.0 1.0 NA 1.0 2.0 4.0 4.0 2.0 3.0 7.0 2.0 2.0 2.0 2.0 4.0 1.0 1.0 3.0 3.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.23602851136906722 0.19619766291266127 0.26442190422786316 GO:0022884 macromolecule transmembrane transporter activity molecular_function 21.419804004183472 20.451382038537265 20.715221788471567 17.544549999226795 18.364543881734207 21.61112024392029 21.091987897420328 17.587805143685383 NA 19.157932928507066 21.37981948990704 21.86525352446176 22.43424417413482 19.939486798331124 20.734843585325496 21.065145377828017 21.245053158296095 20.781382055541734 21.325593450222076 19.04915185717596 21.50559431717227 18.180762800494048 21.771157689085225 20.479140957661823 22.180916632313604 20.861763148400406 6.0 1.0 2.0 13.0 2.0 3.0 NA 4.0 4.0 8.0 5.0 2.0 4.0 11.0 5.0 13.0 3.0 3.0 2.0 2.0 4.0 5.0 5.0 4.0 2.0 1.0 2.0 2.0 1.0 2.0 NA 1.0 3.0 2.0 2.0 1.0 2.0 2.0 2.0 3.0 1.0 2.0 2.0 1.0 1.0 2.0 3.0 1.0 0.9684219656462076 0.026715698447179453 0.047158686933635015 GO:0022890 inorganic cation transmembrane transporter activity molecular_function 28.56990952891307 29.590693234958053 28.378586785768213 28.97310533852554 28.07112723072932 29.403630122166962 28.208152191109036 29.524627789476586 28.379915205174626 29.498923201988678 28.673439714296666 29.634483190126108 28.678111996759558 29.308100837330013 28.347929394008645 30.024029441393303 28.40173822032355 29.756491119197012 29.068219956364732 29.65950123941288 29.03140683131793 29.412511158804946 28.608022384091893 29.82958744732252 28.634418083017678 29.777719488868183 288.0 312.0 267.0 384.0 262.0 419.0 356.0 449.0 327.0 451.0 352.0 343.0 365.0 490.0 267.0 388.0 332.0 464.0 338.0 422.0 319.0 390.0 342.0 533.0 5.0 4.0 4.0 4.0 5.0 4.0 5.0 6.0 6.0 6.0 6.0 5.0 6.0 5.0 6.0 4.0 5.0 5.0 5.0 4.0 6.0 4.0 5.0 6.0 -1.020783706044984 5.312128159411724e-05 0.0005099643033035255 GO:0030001 metal ion transport biological_process 25.55457525716558 25.2024118837139 24.375627026312642 23.023564129969245 24.830727952106372 22.992629876413087 25.40867103698811 25.449311833458786 25.77815152164588 25.994641212562733 25.732826889937634 25.32106913375133 26.071304875916532 25.076470387302717 25.59345112734363 24.78761448299896 26.26543308408846 25.5904948025176 24.843636802659958 25.337822504238922 25.06538122686339 24.65111421238717 25.61500274550844 24.78763825004788 25.92080324522996 26.23994989329835 22.0 16.0 15.0 13.0 41.0 27.0 39.0 39.0 38.0 26.0 45.0 44.0 43.0 33.0 34.0 29.0 20.0 47.0 24.0 16.0 40.0 29.0 48.0 49.0 3.0 2.0 3.0 2.0 4.0 3.0 4.0 3.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 0.35216337345168114 0.13332693177434943 0.18549833985996442 GO:0030060 L-malate dehydrogenase activity molecular_function 27.202952052775878 27.618769663334678 26.58446897871168 18.36452559301795 18.190619928906735 19.176585648918774 26.45640271927709 28.019245690915337 26.45814782599393 28.4071119250596 26.65951331681745 27.771189689902506 27.360225693754426 26.554803078934146 27.364628441978024 27.494537790470858 28.09815478769165 28.51944624110866 27.75232155954773 26.97468464152291 27.95770390679191 26.771469939411546 27.60389875674475 25.8408534467014 27.055752729513394 29.24495047045149 14.0 3.0 1.0 1.0 14.0 14.0 16.0 15.0 14.0 14.0 17.0 12.0 19.0 13.0 15.0 14.0 14.0 16.0 21.0 16.0 16.0 13.0 15.0 21.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4158176105588005 0.6033317722918665 0.6716842567531217 GO:0030091 protein repair biological_process 21.35600502421825 21.209692332735926 19.080768924454482 21.1018622603216 NA 18.315843938342766 20.932519158690265 20.360795144891647 18.36333947117617 20.914121989228967 19.45944628457951 20.46159066813487 18.90935356285953 22.696680127545534 20.072442052787657 21.59499862523879 NA NA 24.05134465038219 21.62099627774004 18.541759577055835 20.23615524781152 19.5790195378953 21.57410618172872 21.555546112515984 20.768366493399288 2.0 2.0 NA 2.0 3.0 5.0 2.0 4.0 4.0 4.0 2.0 8.0 6.0 6.0 NA NA 9.0 8.0 1.0 2.0 1.0 4.0 7.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.14631269148232207 0.09102238821888042 0.13604304251157218 GO:0030145 manganese ion binding molecular_function 26.002947140927464 26.928509909029913 26.751194628511467 26.62178409082396 27.36206461260765 27.024916213412713 25.274810024500127 27.372668944528044 25.13670509146007 26.832656897752546 25.459740053493608 26.835937734104096 25.658341406510374 26.244645711369863 25.859969241278524 27.237319534429087 24.98869911920964 26.549131017175387 26.750427308519274 27.425526257740607 25.96929029200129 26.809572898914727 24.593285784877573 26.97806724557632 25.480127242283334 26.762452685231185 60.0 48.0 86.0 58.0 54.0 66.0 54.0 67.0 60.0 54.0 64.0 42.0 68.0 53.0 62.0 53.0 93.0 88.0 65.0 48.0 57.0 55.0 54.0 61.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9255627681024485 0.0012242832644312096 0.0037265988146589013 GO:0030152 bacteriocin biosynthetic process biological_process 20.895634424951826 24.41654179546976 21.344066307948008 24.38393601052255 21.809663599395247 22.057677717292933 20.300799978373217 25.67524989366701 17.995740830041715 24.65392057517888 NA 22.571843320189338 NA 24.765045606309954 21.839951864890644 23.815464798784838 21.07388872796449 24.388329700618574 21.586610754685157 24.570972159728175 20.122285122322584 24.363170608116523 18.077416230080107 24.855995986819053 20.054049328858664 23.753248645684828 5.0 9.0 4.0 5.0 3.0 8.0 1.0 8.0 NA 7.0 NA 6.0 5.0 6.0 5.0 10.0 6.0 8.0 5.0 6.0 1.0 7.0 2.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.5209073705179357 7.612502462153449e-05 0.0006012913337194623 GO:0030154 cell differentiation biological_process 21.457258924264906 21.665890831572383 20.819435543781072 17.95635950090572 23.19233790376464 22.61134336899392 17.562041778517543 20.20334632571496 20.75642241701872 22.464977195914226 22.068616931438843 22.228777404015045 21.705061557540198 21.015583988932377 18.50144915668874 20.572856605287683 20.162522529894968 21.598039905740343 20.43762096361377 20.543440285900054 21.44615485570013 18.086719298804415 22.60550827334774 23.589134287846786 20.10730370551352 16.15870189808387 8.0 1.0 7.0 10.0 2.0 3.0 2.0 2.0 7.0 8.0 7.0 4.0 1.0 4.0 9.0 7.0 3.0 5.0 6.0 2.0 11.0 6.0 5.0 1.0 2.0 1.0 2.0 3.0 2.0 2.0 2.0 2.0 3.0 3.0 3.0 2.0 1.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 4.0 1.0 1.0 -0.2086319073074776 0.9080725552559752 0.9266349541778063 GO:0030163 protein catabolic process biological_process 23.789509987586765 25.213072978222428 24.008605243688887 25.095037481076282 24.593766819955594 24.624989665510146 23.10220330809657 25.12709213251131 24.20574230885166 24.62513782015291 22.90569510809283 24.877245720347748 24.327179177427354 25.980827159294787 23.3725157600168 25.109534627478762 22.654363120739717 24.44908941538368 24.309147427880262 25.11840961785713 23.74160035810869 25.07922347501021 23.43244089086813 26.03070827885451 23.3836563405208 25.45299626839337 24.0 35.0 34.0 42.0 20.0 41.0 35.0 43.0 19.0 32.0 46.0 39.0 30.0 42.0 20.0 34.0 50.0 45.0 35.0 43.0 32.0 47.0 26.0 58.0 NA 1.0 1.0 NA 1.0 NA 2.0 2.0 NA NA 1.0 1.0 NA NA 1.0 1.0 2.0 1.0 1.0 NA NA NA 1.0 1.0 -1.4235629906356628 4.146041132679973e-05 0.0005099643033035255 GO:0030170 pyridoxal phosphate binding molecular_function 26.747691050492488 25.898373131175852 25.63777344988761 25.55048553384737 24.857464212435268 25.363118949800977 27.272913973480602 25.626053887832953 27.74718755676517 25.66606127411866 27.30831219383037 26.401576191286694 26.66781190784938 26.343206693715 27.257085681914592 25.84437113486722 26.438846120419267 25.597378828566303 27.371883412645985 26.52665584279697 25.359257760510484 25.344106873137264 26.204928543176425 25.969750704936967 25.92883906647788 25.918513287063146 51.0 54.0 41.0 55.0 80.0 86.0 76.0 75.0 100.0 99.0 83.0 84.0 98.0 92.0 65.0 78.0 134.0 105.0 65.0 63.0 78.0 86.0 84.0 77.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.8493179193166362 0.04964722965745621 0.07872902492059129 GO:0030203 glycosaminoglycan metabolic process biological_process 23.931805270055108 25.33543697044978 24.32460388467092 24.908656633832823 24.198211598693987 24.47661030115901 23.040379733558737 26.0550231505226 23.96853445189723 25.13181104943879 23.72152530364603 26.077830789698965 24.224336506835517 25.993422425947642 24.064358849697577 25.083098108873358 24.00630439989525 24.46584697906053 24.266813270921887 25.183851146763878 23.116264914794694 24.74237946272693 23.41935217270582 25.776704604162997 24.13393266713831 24.67102672703301 36.0 47.0 36.0 42.0 31.0 79.0 29.0 67.0 40.0 68.0 49.0 59.0 31.0 63.0 35.0 51.0 61.0 64.0 36.0 52.0 36.0 56.0 51.0 55.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 3.0 -1.4036317003946728 3.225641456243767e-05 0.0005099643033035255 GO:0030234 enzyme regulator activity molecular_function 22.787832297063478 26.476685057844314 19.954782386388906 23.97722280297164 19.10837860753753 27.11434922342373 22.83794850644218 20.556323618119887 23.472986315781803 25.55925347042675 22.49901145671288 25.30704148164585 24.490027607293435 21.42504593274813 22.59263976696432 26.987855032127857 21.93323243752192 28.150187907626442 23.191208667755 26.2069235550478 21.21975251580967 24.641311712204647 22.877775617071272 27.93687560478212 22.65999827646512 26.100541846353888 6.0 36.0 6.0 78.0 6.0 15.0 8.0 57.0 3.0 45.0 9.0 2.0 4.0 123.0 5.0 161.0 20.0 62.0 3.0 41.0 10.0 144.0 7.0 64.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 3.0 1.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 3.0 2.0 NA 4.0 3.0 2.0 3.0 3.0 -3.6888527607808363 0.00268017172806849 0.006910856026093958 GO:0030258 lipid modification biological_process 22.454510894714733 21.420433119670527 NA 19.83082059653252 17.676966163707803 20.42155222395737 22.665261937415828 20.90787096528836 24.087608225505072 20.82656096552633 22.215213219128255 18.79654278208206 22.376269650571267 21.685314114124218 24.102435436991602 22.028394040320173 20.573711636315853 20.80670629498914 20.13996112837955 21.924578904944678 16.95161811831365 19.924904708678685 21.54730142866045 23.420807029389554 22.03648175786885 20.386760383609165 NA 4.0 3.0 7.0 7.0 6.0 10.0 7.0 8.0 5.0 3.0 4.0 6.0 10.0 4.0 8.0 3.0 8.0 2.0 6.0 7.0 15.0 6.0 7.0 NA 1.0 1.0 2.0 3.0 1.0 2.0 1.0 3.0 2.0 1.0 1.0 1.0 1.0 3.0 2.0 3.0 2.0 1.0 1.0 2.0 2.0 3.0 2.0 1.0340777750442065 0.26793808403417974 0.34296074756375006 GO:0030261 chromosome condensation biological_process 28.39069087994673 28.652887763374373 28.30449365490028 27.825294351446534 27.70718834043311 28.027754605280233 28.18092083370441 28.41761622175849 27.731148538180307 28.84892465749486 27.89176050040377 28.92800814030376 28.309340010413194 28.55512560156691 29.325608671427602 29.24122531267528 27.679757215318045 28.533244630023304 27.90281828630365 28.535762970790092 29.545617473590585 28.834846840796057 28.662227423432174 28.868177604378925 27.689779112734733 28.66325320110639 26.0 17.0 28.0 27.0 21.0 24.0 26.0 21.0 30.0 34.0 26.0 31.0 27.0 35.0 21.0 24.0 25.0 37.0 35.0 23.0 32.0 38.0 30.0 34.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.2621968834276416 0.04964722965745621 0.07872902492059129 GO:0030388 fructose 1,6-bisphosphate metabolic process biological_process 26.914328750460008 28.406459049373154 28.114097514842324 27.67410728990561 27.04255085326591 28.143480539669948 26.16522540864157 28.61468322153916 25.384857291584158 28.062905410006824 26.371116598766502 28.421333835702878 26.011988308952798 27.64124510501204 28.24180713540719 28.955661274996014 26.350063274719034 29.133304533219434 27.20148770774008 28.635130149887072 26.93875044048168 28.39572907934539 25.271850342823313 28.344722404925577 26.40764802981132 28.051462658066807 18.0 27.0 22.0 39.0 21.0 45.0 28.0 46.0 25.0 37.0 19.0 27.0 36.0 37.0 24.0 47.0 29.0 23.0 31.0 37.0 31.0 39.0 22.0 37.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.4921302989131462 0.0002755038114342687 0.0011655212090507369 GO:0030409 glutamate formimidoyltransferase activity molecular_function 25.174159776793733 24.486612547211045 26.88312754167028 24.88941604252384 25.795234133693928 21.976124287484797 23.90056142171402 24.425077120543204 23.03024588175705 24.068153133845 24.922998595932256 25.609967115262126 25.254172481672825 22.753190928554826 24.04617801399333 20.591213599577266 25.15934864596311 20.267838972759165 24.728728066079587 26.329247285661825 24.96873443594977 24.257719354951114 24.80116755779079 NA 24.91297791387629 24.082795098579393 14.0 13.0 22.0 5.0 7.0 15.0 10.0 16.0 10.0 14.0 16.0 11.0 9.0 2.0 7.0 3.0 12.0 14.0 18.0 16.0 1.0 NA 16.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.6875472295826874 0.08483774479657043 0.12710384814660253 GO:0030488 tRNA methylation biological_process 19.904682767163862 21.187133692495703 21.801081629135 18.74601185081368 20.916950245457887 22.509603592419698 15.68090807351053 21.413284701278783 18.293925363031935 19.926430786045454 19.417450576072785 21.190590565394785 17.2449787637476 16.904191273340665 20.31458079700036 22.38170288182971 18.176029196938558 21.147425795117627 19.468033636237443 21.00855953291196 19.64577238310737 21.11966136380212 NA 20.987808951326876 19.58745292600028 20.680047574877367 2.0 3.0 6.0 14.0 1.0 7.0 1.0 5.0 3.0 5.0 2.0 1.0 3.0 14.0 2.0 7.0 4.0 6.0 3.0 7.0 NA 8.0 4.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.2824509253318404 0.01934898020033666 0.03636675796689782 GO:0030632 D-alanine biosynthetic process biological_process 19.30916389943202 19.285763146036984 19.202299444738028 17.39079850763817 18.57856069100217 18.62667408657724 19.955548692862955 16.834663721407313 19.67662208401689 20.323115913417016 20.428979015907853 20.74195022703785 19.77097037805543 17.619836130762287 17.538105822408834 18.46329643919817 19.769653455599773 16.701082906104418 18.10834268670508 19.45446928911084 17.899298398866197 18.44312480447125 17.73156186889231 19.518259577422565 19.628265619116693 20.43296281856506 3.0 1.0 1.0 1.0 2.0 1.0 4.0 3.0 5.0 4.0 3.0 3.0 1.0 3.0 4.0 1.0 2.0 4.0 1.0 2.0 1.0 2.0 2.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.023400753395034002 0.5253727863737021 0.6008633207515945 GO:0030650 peptide antibiotic metabolic process biological_process 21.89563442495183 25.41654179546976 22.344066307948008 25.38393601052255 22.80966359939525 23.05767771729293 21.30079997837321 26.67524989366701 18.995740830041715 25.65392057517888 NA 23.571843320189338 NA 25.765045606309954 22.839951864890644 24.815464798784838 22.073888727964487 25.388329700618574 22.586610754685157 25.570972159728175 21.122285122322584 25.363170608116523 19.077416230080107 25.855995986819053 21.054049328858664 24.753248645684828 10.0 18.0 8.0 10.0 6.0 16.0 2.0 16.0 NA 14.0 NA 12.0 10.0 12.0 10.0 20.0 12.0 16.0 10.0 12.0 2.0 14.0 4.0 12.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -3.520907370517932 7.612502462153449e-05 0.0006012913337194623 GO:0030698 5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity molecular_function 19.62470618883679 21.934411660611893 20.52244605636407 21.3830781949611 19.6134069075922 22.1180912405628 19.054839499101863 22.45801166349466 19.72469529417517 21.898251726579307 19.784965030939425 21.498729734488503 18.883656683155863 22.023442451689572 16.465790883882512 22.665876222668306 NA 22.496203882490626 NA 21.555140420085028 NA 21.182079678952284 NA 22.363077640465217 20.276810213098 18.889469421629148 4.0 6.0 5.0 12.0 2.0 11.0 5.0 10.0 4.0 6.0 2.0 13.0 1.0 15.0 NA 16.0 NA 6.0 NA 9.0 NA 18.0 6.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.3097054717751035 0.001193745444872003 0.0037265988146589013 GO:0030788 precorrin-2 C20-methyltransferase activity molecular_function 20.954706445191647 21.837346228413885 19.027343714430067 NA NA NA 20.50550700526421 21.832622451948048 21.463627478810505 23.29504506035336 20.360163890701426 22.142696121546635 20.748072747727626 20.33308041466021 20.306478775336345 18.991993711266066 21.37005513075142 21.33417234390869 21.452641919145066 21.277862818945238 21.129077842101022 20.93309968702108 20.809934726835557 20.06983452848875 21.664855981329822 23.049650242530173 1.0 NA NA NA 3.0 6.0 8.0 7.0 3.0 5.0 4.0 2.0 6.0 3.0 6.0 3.0 5.0 4.0 6.0 4.0 7.0 4.0 9.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8826397832222383 0.3981027163512083 0.4809604937137541 GO:0030955 potassium ion binding molecular_function 23.50017244765008 24.069477821181717 23.552036251221256 21.395548620126874 20.14163442827945 21.328886303618397 22.630934082054466 25.21074184972845 24.48759790049909 23.917642346840573 23.69348076569595 23.55345914506368 23.078815374166762 24.158126930789674 23.962301011216432 23.422050136438244 22.65555413663683 23.753195628823203 24.51525763135035 23.508365872186374 22.810489057220913 21.11687981936751 23.748573125832767 25.68510479703408 22.948832029092532 24.666127603677143 6.0 1.0 4.0 2.0 10.0 20.0 20.0 4.0 15.0 7.0 10.0 3.0 18.0 2.0 6.0 7.0 12.0 12.0 4.0 2.0 16.0 3.0 11.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5693053735316376 0.4189234409463829 0.5022252202700153 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex cellular_component 22.475357086087733 24.16515820910988 22.077404906899115 22.93157855549272 22.083703157099926 24.710745677405573 21.583663671760398 24.14747051909216 22.8986037926633 23.866216103510236 22.583735244035765 23.635500569919877 23.24889344808195 23.29396408538509 23.221644581267796 24.63136318888091 22.25917220090011 24.942092977569214 21.928560378529948 23.25136985185936 20.812432266219307 24.205945041251315 22.49813156065111 24.833829471285835 22.80517988695508 23.89811110414407 12.0 15.0 19.0 29.0 9.0 23.0 15.0 29.0 14.0 21.0 15.0 17.0 20.0 26.0 12.0 30.0 13.0 23.0 10.0 21.0 14.0 33.0 14.0 31.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.6898011230221464 5.312128159411724e-05 0.0005099643033035255 GO:0030976 thiamine pyrophosphate binding molecular_function 27.923319754309677 26.83153172566187 24.625111419584524 13.777760006384304 16.389452525881946 NA 28.124974552229556 26.70404835060856 28.75678120139091 27.81806014526582 28.659742241029786 26.860779733536237 28.22258721854812 25.39856778592456 28.814474693082943 26.068892673839827 28.514150350604982 26.668330079961592 26.720132930250625 26.898162806962624 25.866922227264123 26.06634938129484 27.70298830817489 25.02640051299356 28.156718631021906 28.55746233826488 18.0 1.0 1.0 NA 75.0 26.0 97.0 28.0 95.0 24.0 74.0 18.0 103.0 26.0 72.0 26.0 72.0 58.0 37.0 26.0 72.0 22.0 83.0 29.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0917880286478088 0.08483774479657043 0.12710384814660253 GO:0030983 mismatched DNA binding molecular_function 21.33240455045316 19.77681572491272 NA 17.723668518816407 NA 19.195170580187753 20.70213105247516 19.37281855629954 22.39801590491269 NA 21.087299286302066 16.19150343483952 21.196693060604375 20.71919139181221 21.627474218985128 20.88682279133872 20.832047320342923 20.133468099806628 17.05304768262557 16.99404480022293 NA 17.29617663089701 21.43828670234348 21.44444248458248 21.863862192981266 18.417491584201592 NA 1.0 NA 2.0 7.0 4.0 21.0 NA 11.0 2.0 11.0 4.0 13.0 6.0 8.0 6.0 1.0 2.0 NA 1.0 14.0 11.0 20.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.5555888255404398 0.013543601483181442 0.026786711015864405 GO:0031071 cysteine desulfurase activity molecular_function 21.224971077660307 21.95718456494453 16.804270174351768 21.679979197920964 17.772250146811928 21.94386748146464 18.7313410287156 20.84276598535131 21.859329193975878 20.784493666190468 21.76003321753189 21.76218360346147 21.66715890655551 23.276868779697388 21.840483920140237 22.817074115557705 22.065714607813128 20.429260815309632 19.638693742559546 21.70816448871819 19.209146315329363 21.168211004838806 21.85162012331329 22.744208479683408 22.133514665508127 21.223659662947068 2.0 9.0 2.0 11.0 2.0 13.0 7.0 8.0 4.0 13.0 6.0 18.0 10.0 13.0 5.0 9.0 4.0 16.0 5.0 9.0 10.0 12.0 5.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7322134872842234 0.29869755599497017 0.3712893923124729 GO:0031072 heat shock protein binding molecular_function 21.13849419577424 24.36033444516686 19.607475003066998 24.04083702351705 20.24724463006177 24.55939704315727 21.408233988629394 25.02305019796796 18.74728490983094 24.06446905417222 20.855004588821558 23.89514998376885 21.900397110460982 24.33052319535554 20.3933712293537 24.46696794536586 21.427222721212875 23.983068003961826 22.164636399457564 24.25958632425775 21.761302201027174 23.889717355996265 20.602281597957045 25.22547774482193 21.298227453084976 23.686400054701405 2.0 9.0 3.0 5.0 8.0 12.0 1.0 10.0 5.0 8.0 7.0 10.0 2.0 10.0 7.0 9.0 7.0 13.0 4.0 6.0 5.0 10.0 8.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.2218402493926206 3.225641456243767e-05 0.0005099643033035255 GO:0031090 organelle membrane cellular_component 25.25576947040763 21.69689519506732 22.20071538816792 NA NA 19.909592563729174 26.471648733111163 21.67712836242525 22.50784021198638 18.9587106033491 26.16154598447792 20.22175956589286 26.08186253954825 NA 25.84609251065596 22.93668835308307 22.436792397908594 19.007297425997816 22.527731811258963 23.767770776140672 24.037721983966584 19.600282985973468 20.924582580567826 NA 26.5683139507319 19.766987417986048 4.0 NA NA 1.0 11.0 3.0 7.0 3.0 12.0 1.0 10.0 NA 9.0 3.0 5.0 3.0 7.0 4.0 3.0 1.0 6.0 NA 13.0 4.0 2.0 NA NA 1.0 4.0 2.0 1.0 2.0 3.0 1.0 3.0 NA 4.0 2.0 1.0 2.0 1.0 2.0 2.0 1.0 2.0 NA 4.0 2.0 3.558874275340308 0.0034446936330652616 0.008429367949147934 GO:0031167 rRNA methylation biological_process 21.791938890592323 22.502871925524975 23.32266788772752 21.30853817799619 22.125130497267293 22.72586597947637 19.47628318980364 22.49603347827971 18.64189406923416 21.457337138956003 21.57607772197019 23.047796340610482 22.08321215171811 22.219170790521325 23.03834526277215 23.796198851780144 20.51908809491272 22.05580770887206 20.88197660849349 22.01607585149748 22.357735669860066 22.164160055923933 18.51830648488816 22.870569516482306 20.93065428054417 21.895936869110546 8.0 13.0 8.0 20.0 6.0 17.0 2.0 13.0 12.0 22.0 12.0 13.0 10.0 29.0 6.0 20.0 9.0 10.0 10.0 8.0 5.0 25.0 11.0 12.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 -0.7109330349326513 0.06467168750236378 0.10076188015349562 GO:0031224 intrinsic component of membrane cellular_component 29.18282697284789 28.66802061687307 28.72847844999534 28.12860796391942 28.564756412515806 28.239552483553272 28.837689531465635 28.30240621084385 28.872143768317947 28.270729229879603 29.455820091494182 28.95552830861121 29.812110309987048 29.14767550164937 28.917336055839485 28.738575563280055 29.05796713358961 28.71277035397965 29.366534013772174 28.99534188693638 28.94672064200191 27.97473056942533 29.39265177452492 29.142203774551593 29.64710685851571 28.77189851162885 361.0 437.0 322.0 445.0 290.0 537.0 384.0 545.0 421.0 649.0 598.0 658.0 394.0 624.0 331.0 605.0 465.0 627.0 415.0 439.0 404.0 692.0 472.0 656.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 4.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.514806355974823 0.017926339076638688 0.03379466943753034 GO:0031323 regulation of cellular metabolic process biological_process 29.815139854922446 30.467408190562292 29.936245579118857 30.081970616987014 30.02801049095559 30.38505875425964 29.43371179584885 30.7260847712426 29.63123133509973 30.651559586090865 29.77968327258811 30.597204616885104 29.822971543709887 30.31364307952484 29.794885824388395 30.363153658207175 29.22688738535781 30.36512422816073 30.282534423476395 30.891668644302438 30.00203029241927 30.19433097366896 29.683698022257357 30.28624442040961 29.870665774480077 30.539300184022512 653.0 733.0 635.0 726.0 676.0 1005.0 758.0 1032.0 893.0 937.0 912.0 816.0 704.0 916.0 585.0 947.0 1156.0 1120.0 800.0 712.0 693.0 938.0 912.0 1086.0 7.0 7.0 7.0 8.0 8.0 8.0 7.0 7.0 7.0 7.0 9.0 7.0 6.0 8.0 7.0 7.0 7.0 7.0 8.0 7.0 7.0 7.0 7.0 7.0 -0.652268335639846 5.312128159411724e-05 0.0005099643033035255 GO:0031324 negative regulation of cellular metabolic process biological_process 24.22589616922825 23.82939313578628 22.923517845840212 23.632440927263016 24.864671062381145 23.049929497761656 24.27499415138215 22.998279002959052 23.094518873822018 24.80843912685371 24.716041321455158 23.322814949790395 24.856440495229158 23.677707476218988 23.40511519826639 21.8185571872786 23.157194349828373 22.682772716582168 24.314877379447584 25.310009151553945 24.983439642206 23.265936601237076 23.76783118632124 23.161900492454066 24.32165868797994 24.51727041803608 31.0 39.0 45.0 21.0 43.0 40.0 46.0 53.0 53.0 32.0 68.0 34.0 29.0 24.0 24.0 34.0 56.0 68.0 50.0 39.0 40.0 34.0 60.0 63.0 2.0 4.0 4.0 2.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 2.0 2.0 4.0 3.0 5.0 3.0 2.0 4.0 4.0 4.0 2.0 2.0 0.39650303344197013 0.16585666034291002 0.2267131567447445 GO:0031325 positive regulation of cellular metabolic process biological_process 23.629973660822234 24.25602474303417 23.9314560892023 23.560246200831408 22.38884354359095 24.33280715650935 22.706433613960467 24.31438250665093 24.54136647838525 24.156855681635022 24.360141698483076 24.488492197713214 23.59104405297653 24.10445620761567 23.788536217330623 24.239260277067253 23.22107777113423 24.3685536430684 23.094378608334345 24.1967280775452 22.769681224774533 23.434196682510105 23.471542390472685 25.017859066957783 24.006461342312694 24.237623522099057 30.0 38.0 19.0 40.0 28.0 65.0 49.0 63.0 48.0 54.0 33.0 41.0 31.0 76.0 33.0 71.0 34.0 52.0 27.0 34.0 38.0 71.0 46.0 58.0 4.0 3.0 3.0 3.0 3.0 3.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.6260510822119372 0.013042519940568903 0.025877686622941164 GO:0031326 regulation of cellular biosynthetic process biological_process 28.51748050936154 29.372480418111024 28.711931889543784 28.999147045273517 28.84681264854282 29.16145239395981 28.061505611121873 29.646842091644203 28.23236952525589 29.620079393260017 28.44428655772757 29.50065640859741 28.54270340027111 29.18637173685432 28.395711493331746 29.293700707647496 27.839620949246587 29.306508398745212 29.058901561973013 29.82422757544538 28.75651700571325 29.065326029466767 28.305840598311125 29.170819840742663 28.57142417896709 29.43994056981306 305.0 358.0 297.0 346.0 308.0 480.0 305.0 485.0 394.0 435.0 412.0 407.0 311.0 422.0 263.0 444.0 565.0 531.0 371.0 339.0 293.0 444.0 404.0 509.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 4.0 6.0 6.0 6.0 7.0 6.0 4.0 6.0 6.0 6.0 6.0 6.0 -0.854999908749484 4.146041132679973e-05 0.0005099643033035255 GO:0031327 negative regulation of cellular biosynthetic process biological_process 23.385732461200032 23.207729278941088 22.30030518237217 23.007691038230053 24.246162682527967 22.464966997040506 23.42263975013986 22.403375515281333 21.83512001622161 24.20906481771488 23.745606760480214 22.6375480396986 23.89861773367821 22.950070591193576 22.433366644229814 21.233594686557442 22.048272926497187 22.078096615980353 23.1721939722462 24.721564622589497 24.383694368145203 22.632627258704492 22.941434045243287 22.463458014127763 23.56031329159957 23.89656886761437 20.0 25.0 28.0 14.0 25.0 26.0 20.0 34.0 27.0 20.0 37.0 20.0 14.0 16.0 11.0 22.0 29.0 44.0 33.0 25.0 18.0 21.0 32.0 41.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.1780031822589443 0.5637028616507731 0.6360770084449954 GO:0031328 positive regulation of cellular biosynthetic process biological_process 21.972007638553986 22.86511762035008 22.370152744534078 22.21856497907633 20.81136861212874 22.93164219205457 21.13719494790987 22.93762041672264 22.802478396133004 22.75146906942937 22.78163914358533 22.97672304740037 21.99087022295184 22.600506099407877 21.219753686746568 22.835016859025608 21.71154286980865 23.31154870303079 21.531778361699 22.871667803031336 21.184718724053376 21.946992614852096 21.982741124474806 23.60706858979938 22.434181893395106 22.67603686671784 11.0 14.0 7.0 14.0 10.0 23.0 16.0 21.0 16.0 18.0 11.0 15.0 9.0 26.0 12.0 25.0 12.0 18.0 9.0 12.0 14.0 25.0 16.0 20.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 3.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 -0.8931099817960941 0.0012242832644312096 0.0037265988146589013 GO:0031347 regulation of defense response biological_process 21.29775421693052 20.90173757029197 21.8850984655715 18.946598677454432 16.575122315878428 19.036822482132038 NA 19.75054074741549 21.545710627545095 16.679699958635613 23.12926176569399 19.192332932132175 21.969198957499103 22.520796736641504 20.15998864658186 19.98760677269276 19.913101321240045 20.36416998736443 19.679459650308583 19.154067495449077 18.90722634291203 16.294162422480262 20.914094996392574 23.231664776463557 NA NA 6.0 4.0 2.0 4.0 NA 2.0 11.0 2.0 6.0 4.0 4.0 2.0 4.0 4.0 2.0 6.0 2.0 4.0 4.0 2.0 4.0 6.0 NA NA 2.0 2.0 2.0 2.0 NA 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA NA 0.3960166466385502 0.2908457067435437 0.36699677778858775 GO:0031406 carboxylic acid binding molecular_function 26.887278211768 25.794917863606983 26.436451289436512 24.873466246426958 26.093164989511447 25.637537970439663 26.87740810494453 26.166490896466236 26.856823580866212 25.85809099010861 27.03290017003844 26.383098226900405 26.85928771068832 25.67756141726264 27.268576739118124 25.609261950931355 26.895600112652826 25.68547082790936 27.458801632282675 26.41406589148757 25.52150729475536 25.904012663302865 27.27894562312582 24.850792597867432 27.073862560930714 25.595936809425893 20.0 15.0 11.0 10.0 33.0 51.0 31.0 38.0 32.0 35.0 45.0 39.0 42.0 34.0 35.0 38.0 35.0 37.0 28.0 23.0 41.0 36.0 41.0 40.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 1.0923603481610158 0.0006583371695572323 0.0022696264851033866 GO:0031419 cobalamin binding molecular_function 25.809595472110466 25.153990416551906 23.481588479739322 NA NA NA 25.697579748822232 24.75508973566513 24.56956905829464 25.47388024979027 25.49983169814185 24.70945428871895 26.42647595017929 24.451140795717357 26.07214732485033 24.95609639437756 25.877917750524567 24.77104014657102 26.65318424260365 25.032605317861535 25.563612398290118 24.85428922096438 26.338481563598727 25.15663000927903 25.45703449946352 26.337892358464018 3.0 NA NA NA 13.0 4.0 14.0 6.0 17.0 6.0 14.0 3.0 12.0 3.0 15.0 4.0 23.0 11.0 10.0 2.0 12.0 2.0 23.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.65560505555856 0.04113977904099392 0.06818385689662737 GO:0031564 transcription antitermination biological_process 23.68931265547349 25.500818685727914 24.838999271834844 25.30665268824259 23.698215389763646 24.89939013818034 22.718454363888544 25.81569039899651 22.38249312365797 25.545847267073196 23.147049862419358 25.78789958055339 23.48865591096024 25.6770862432794 23.73922629784585 25.33108685697397 23.119445497391826 25.25469756825985 24.966487665907284 25.76956974464889 23.531940163749162 24.9124664891352 22.521832684982428 26.108477134239997 23.419654765602466 25.01738216411416 25.0 28.0 16.0 23.0 16.0 44.0 16.0 45.0 23.0 40.0 21.0 34.0 22.0 34.0 23.0 40.0 45.0 45.0 18.0 26.0 17.0 37.0 25.0 41.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.8115060302544244 5.312128159411724e-05 0.0005099643033035255 GO:0031640 killing of cells of other organism biological_process 24.079085749227254 24.228018232799233 23.626664293860426 23.97722991137997 19.111803098354727 20.913283609630216 24.3009817178623 23.976400230144428 23.70548231703476 24.53785896619175 25.359840495163002 25.45584665870471 23.98539852256832 24.87084732353256 NA 21.308201346282086 24.50525798992464 23.74396471124661 24.14989193155289 25.03933277673812 20.05808151610553 NA NA 23.221027792494016 24.64151282738551 24.193718691006133 6.0 6.0 6.0 6.0 6.0 13.0 6.0 6.0 6.0 13.0 6.0 7.0 NA 12.0 6.0 12.0 6.0 6.0 6.0 NA NA 12.0 6.0 6.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 NA NA 2.0 2.0 2.0 -0.1489324835719792 0.72477122130619 0.7743276961229171 GO:0031667 response to nutrient levels biological_process 22.71548036340739 22.88238451472717 22.06557153237473 22.392267410658814 17.526840597633566 19.32832110890906 22.90598428111191 22.791034417264193 22.382207501232518 23.51307077212306 23.88504796255428 23.94870322414945 23.01255356766716 23.348657274886303 21.743672298094868 20.904424173953558 23.108262348323056 22.380062426345688 22.866036199333358 23.464703577996517 22.895892544152137 21.125299010836248 21.11378208038753 21.874623692258048 23.325980783920013 23.875222841244355 4.0 2.0 2.0 2.0 7.0 8.0 6.0 6.0 6.0 6.0 7.0 4.0 2.0 6.0 6.0 8.0 6.0 4.0 4.0 4.0 6.0 6.0 7.0 6.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.16690415131978042 0.7728299926844475 0.8146045868836069 GO:0031668 cellular response to extracellular stimulus biological_process 24.500861930067092 25.10911522647369 24.856360151984248 25.14069849175673 24.81476827415571 25.41766559043181 24.33091054484188 24.7976888179272 23.88557523985317 24.809869906167197 24.59706786690895 25.583708661826506 24.738207396871786 25.058170367446962 23.919187426543132 24.678276518354732 23.7751644420302 24.864782349982534 24.81713948888422 25.382834198550558 25.054710138525852 24.58108494152913 23.981687050277948 25.06020909879409 24.50701996474956 25.49970040868086 39.0 33.0 39.0 49.0 25.0 43.0 36.0 38.0 48.0 59.0 55.0 52.0 25.0 57.0 22.0 49.0 41.0 49.0 37.0 30.0 36.0 62.0 54.0 49.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 -0.6082532964065983 0.00268017172806849 0.006910856026093958 GO:0032101 regulation of response to external stimulus biological_process 21.190634645530373 20.90173757029197 21.8850984655715 18.946598677454432 16.575122315878428 19.036822482132038 NA 19.75054074741549 20.21437693701347 16.679699958635613 23.12926176569399 19.192332932132175 21.969198957499103 22.520796736641504 20.15998864658186 19.98760677269276 19.913101321240045 20.36416998736443 19.679459650308583 19.154067495449077 18.90722634291203 16.294162422480262 20.914094996392574 23.231664776463557 NA NA 6.0 4.0 2.0 4.0 NA 2.0 4.0 2.0 6.0 4.0 4.0 2.0 4.0 4.0 2.0 6.0 2.0 4.0 4.0 2.0 4.0 6.0 NA NA 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA NA 0.2888970752384026 0.324206575396745 0.4012639356708831 GO:0032153 cell division site cellular_component 25.74385131793793 26.972710939876087 26.53220827555409 26.682783657452745 25.92586865143523 26.099768456632987 24.529614626018127 27.029602846017212 24.17548428549717 27.032750400040694 24.49794169478796 27.122865382263175 25.043389126855363 26.82718190466552 26.55907029246416 27.38500283865572 25.4141052292407 26.826177042062344 26.429256690369428 27.45564441713481 26.14579698658104 26.614446211774005 25.946381741542112 27.234854125917266 25.22477315493781 26.8655474233781 43.0 34.0 38.0 39.0 30.0 53.0 18.0 53.0 30.0 44.0 28.0 36.0 56.0 65.0 27.0 55.0 59.0 56.0 39.0 49.0 35.0 64.0 33.0 53.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.228859621938156 8.637667594722788e-05 0.0006159890947550879 GO:0032261 purine nucleotide salvage biological_process 25.714342497716807 26.1966668800532 25.705701962838525 25.95645619233294 24.650823844882925 25.781392556204338 26.561651012435327 26.3998906624822 25.401345768994464 26.52264173564889 26.233101341025986 26.152028883508574 26.478383204189768 25.842173552873223 24.979420213525113 26.3334879249728 25.385748766677608 26.322396385074764 26.02745078602673 26.234930474382463 25.096029868641327 25.835457731633788 25.220513073603676 26.532726862257515 25.37667830832073 26.180435520027014 40.0 39.0 26.0 32.0 42.0 46.0 38.0 47.0 47.0 49.0 46.0 35.0 41.0 48.0 39.0 50.0 55.0 59.0 34.0 37.0 39.0 44.0 41.0 54.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 -0.48232438233639385 0.02092133533779403 0.038284203081476474 GO:0032264 IMP salvage biological_process 21.188075374006875 23.71964322556443 22.807311903689648 24.092090329716292 20.77202212696804 21.473697648467173 20.732357185031105 24.187540625685592 20.01611049781431 23.77223181091538 20.409668286863415 23.01678787089239 20.67080348749221 24.21761125167693 21.99474658662712 23.261461397687945 20.7276146742918 22.970604207392487 21.637045129249373 23.848935481479806 20.68324536984974 23.083285608081752 20.010169419096844 24.813868847012877 20.745876703540453 23.49002988210516 7.0 14.0 3.0 4.0 6.0 12.0 5.0 14.0 6.0 11.0 3.0 10.0 7.0 11.0 6.0 11.0 12.0 15.0 4.0 8.0 4.0 12.0 4.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.531567851557554 6.784570247173055e-05 0.0005498145239267514 GO:0032268 regulation of cellular protein metabolic process biological_process 27.66056283465539 27.98816599962584 27.7528679490337 27.582227987953768 27.669639475408612 28.217872397207607 27.401280412929392 28.262809742414216 27.50514030623557 27.926334693796946 27.604758079248427 28.109186481649946 27.599397082084646 27.91785741816524 27.759301104387628 27.87470337622575 27.27044306873933 27.83909122530932 28.081412783480737 28.271719270599647 27.74080103017557 27.83980262549108 27.678928994948482 27.81943515737369 27.704710188009805 28.03038269763389 77.0 69.0 72.0 90.0 78.0 107.0 97.0 103.0 105.0 112.0 93.0 78.0 89.0 113.0 75.0 108.0 124.0 112.0 91.0 76.0 88.0 102.0 93.0 112.0 2.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 2.0 -0.32760316497044784 0.0012242832644312096 0.0037265988146589013 GO:0032350 regulation of hormone metabolic process biological_process 18.81338937569021 22.227832257599808 17.626504117462254 21.70048912666737 15.387498233203914 22.038066902572755 16.779595709460967 22.21197536522675 19.708586819272174 22.428791261908913 20.49485955229591 22.724549961029872 15.47420556183059 20.575634498777784 NA 21.918579820885924 17.832795204320984 23.77526375921727 17.678979733223837 22.440866583984967 NA 20.184912995997912 20.19768541986015 22.64060204939921 17.76804938142643 18.886685702334713 3.0 6.0 3.0 3.0 3.0 6.0 3.0 3.0 3.0 6.0 3.0 6.0 NA 3.0 3.0 6.0 3.0 3.0 NA 3.0 6.0 6.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 -3.414442881909597 0.00028718585599843356 0.0012027112358592117 GO:0032501 multicellular organismal process biological_process 22.33823018349124 22.14618625341031 21.41693138881423 20.489270389237454 23.306772991436702 21.22131114692269 17.85101665153047 21.261280287454017 20.68956883670316 17.651678649324868 23.786784200218676 23.25267748947412 24.207908381614597 24.21394584785604 21.739483066234406 22.036965441315022 21.002629735504783 21.54061685049069 20.66249412170536 20.280645045531443 21.92512733300041 21.6298171875328 21.55881684971988 22.844743021445517 18.384904382432264 17.639077935975514 5.0 4.0 8.0 6.0 1.0 4.0 4.0 2.0 5.0 5.0 6.0 7.0 7.0 8.0 3.0 6.0 2.0 3.0 5.0 3.0 4.0 6.0 2.0 1.0 3.0 3.0 3.0 3.0 1.0 3.0 3.0 2.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 3.0 2.0 2.0 3.0 3.0 3.0 3.0 1.0 1.0 0.19204393008093135 0.7290344895388041 0.7743276961229171 GO:0032502 developmental process biological_process 24.16095092346799 25.285039235984968 25.37416013372425 24.38635772378097 25.60189163508291 25.90221568011628 21.799734589950265 24.870158056724684 21.80939576590549 24.95787374650497 24.223562173277426 25.404655215976693 24.034089621190315 25.660130635961753 23.437276089002648 25.394732533751828 23.130542145363226 24.81665005446187 23.547461187436948 24.904679715419746 23.76858045018664 25.17484929932643 24.733486276126023 26.230371094141933 23.46664398973236 24.49190607636844 47.0 26.0 48.0 67.0 13.0 41.0 11.0 35.0 34.0 54.0 41.0 37.0 22.0 53.0 38.0 51.0 28.0 40.0 26.0 35.0 46.0 48.0 41.0 48.0 5.0 3.0 6.0 6.0 5.0 4.0 5.0 5.0 5.0 5.0 6.0 4.0 6.0 6.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 -1.124088312516978 0.0018227351663913985 0.005134928866041682 GO:0032553 ribonucleotide binding molecular_function 31.07312238222484 30.930386061801862 30.31727096967583 30.26384933271011 30.26618448644903 31.04526911586441 30.82695450765045 31.058149401037987 31.24185093254915 30.83836659527202 31.398111705722524 31.030924969505072 31.197016175368 30.71573811548378 31.13003675912841 30.985196177926888 30.64929115530042 30.84314766302851 31.680207012245997 31.151785786410407 31.25368410183329 31.003288634268962 31.153316272543893 31.01166049220464 31.112033002422393 31.023494204348545 797.0 837.0 738.0 1080.0 1181.0 1330.0 1418.0 1232.0 1441.0 1258.0 1403.0 1034.0 1475.0 1259.0 1074.0 1273.0 1818.0 1597.0 982.0 1027.0 1335.0 1235.0 1347.0 1285.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.1427363204229799 0.11903289845700783 0.16804644488048165 GO:0032555 purine ribonucleotide binding molecular_function 31.060796761912478 30.909311742639485 30.30748995391971 30.246118063049593 30.26274967968156 31.038496841322075 30.819571052235066 31.038966807639035 31.224832522617326 30.83255178921338 31.38418279575665 31.02543176491776 31.182586810102162 30.639979939895905 31.11730021222364 30.978356700958393 30.643996619674645 30.837956201097388 31.652670299122768 31.14465481190977 31.24809359884933 30.977476267939164 31.144959870265627 30.940013346351773 31.104714110952482 31.00862836954427 780.0 824.0 730.0 1061.0 1154.0 1297.0 1387.0 1215.0 1406.0 1232.0 1369.0 1016.0 1445.0 1238.0 1058.0 1253.0 1783.0 1569.0 959.0 1000.0 1312.0 1215.0 1320.0 1258.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.15148501927299307 0.10596880912720232 0.15148805703407617 GO:0032559 adenyl ribonucleotide binding molecular_function 30.028028008996174 30.44073066795019 29.45430587067031 29.95113615981707 29.56489227733926 30.51316805433061 29.840105094137314 30.697976855649088 30.186267140645032 30.29005219720391 30.477117291238137 30.47729938082034 30.20025224351169 30.239144541832648 30.108947514813078 30.645209953698 29.717704001287554 30.458870386042676 30.599549918742643 30.67690175370236 29.698162981261248 30.29879159785269 29.836777326185647 30.484910529413856 30.159282277905607 30.389051896351198 599.0 719.0 624.0 904.0 944.0 1110.0 1114.0 1012.0 1161.0 1026.0 1163.0 891.0 1157.0 1064.0 853.0 1069.0 1488.0 1299.0 753.0 847.0 1062.0 1050.0 1085.0 1057.0 3.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 -0.4127026589540179 0.0022136919545913893 0.006045268182341475 GO:0032774 RNA biosynthetic process biological_process 27.95432528374198 28.61574998093681 27.867250412760143 28.05856268965108 27.604292404848362 28.24396084534812 27.4668314436696 28.8370651366332 27.840243094017968 28.776713564981552 28.08222464394225 28.87518327596581 28.22355785766473 28.431194032714032 27.90437774683452 28.793976232886877 27.337055362648268 28.631823076343068 28.62146836795473 28.97955164833407 27.85250003052793 28.173342516271443 28.28465203309269 28.693486668173307 27.87110994121799 28.565872981668072 247.0 240.0 210.0 252.0 235.0 361.0 282.0 334.0 310.0 360.0 289.0 315.0 341.0 340.0 223.0 349.0 474.0 412.0 263.0 251.0 316.0 350.0 294.0 338.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 5.0 6.0 6.0 6.0 6.0 6.0 5.0 5.0 6.0 6.0 -0.6614246971948283 0.00042856814449695465 0.0016457016748683058 GO:0032784 regulation of DNA-templated transcription, elongation biological_process 22.971786713495533 22.005925297860173 22.486211345069126 19.215061079329907 NA NA 23.0830642145254 21.517967541972727 17.18323227692474 22.60880950225166 23.715724707067643 22.618647785008413 23.60939285816493 22.348840879556814 19.18374758298313 22.040698615091845 20.279054366737086 21.75217819798799 23.21184711385484 22.206947985900324 23.81937810926344 20.742382082209208 23.20919196903276 20.9409887356693 23.62306323591494 22.946370490580488 3.0 1.0 NA NA 1.0 2.0 1.0 5.0 7.0 4.0 7.0 4.0 1.0 3.0 3.0 3.0 9.0 4.0 4.0 1.0 1.0 2.0 5.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.9658614156353593 0.09404066637444118 0.1379524750629327 GO:0032787 monocarboxylic acid metabolic process biological_process 30.334120651350627 30.921617433325004 30.437904722256338 30.16912592137063 30.01855808410984 30.919022555693545 29.874882962721014 31.111489240168424 29.885522397203626 30.90952836577004 30.43118280042789 30.85225916715393 30.34731487854704 30.350204592484165 30.825425103569692 31.22732634632474 29.91770673571236 31.41243647302184 31.07595132632355 31.187100713903842 30.173857076482633 30.808086889660643 30.20755640658039 30.885900589099464 30.25220145031669 30.78032285277924 373.0 317.0 432.0 489.0 511.0 598.0 625.0 559.0 624.0 538.0 564.0 361.0 672.0 511.0 510.0 568.0 845.0 645.0 527.0 486.0 593.0 480.0 562.0 549.0 8.0 7.0 9.0 10.0 12.0 8.0 12.0 9.0 14.0 11.0 12.0 10.0 13.0 10.0 12.0 10.0 15.0 12.0 13.0 10.0 14.0 12.0 14.0 11.0 -0.5874967819743766 0.00268017172806849 0.006910856026093958 GO:0032879 regulation of localization biological_process 23.691315719084486 23.128968901684303 NA NA NA NA NA NA 25.30690422614716 23.196822902514988 21.78654631525887 24.77824734350533 17.262816046173874 NA 23.14930833109417 NA NA 20.41390421986252 14.901629640847814 18.288447521332145 NA NA 24.66796606762226 NA NA 22.457528246499773 NA NA NA NA NA NA 31.0 28.0 9.0 31.0 3.0 NA 28.0 NA NA 6.0 1.0 3.0 NA NA 31.0 NA NA 6.0 NA NA NA NA NA NA 4.0 3.0 1.0 4.0 1.0 NA 3.0 NA NA 1.0 1.0 1.0 NA NA 4.0 NA NA 1.0 0.5623468174001829 0.8551321405847059 0.8893374262080941 GO:0032991 protein-containing complex cellular_component 31.51537170682827 31.63847721683977 31.21297131807909 31.156355528257684 31.23209223904111 31.591412020130118 31.05347152971393 31.6511878930297 31.654180743646283 31.434533499396505 31.581513075795414 31.772898253125852 31.62017761785123 31.61832355933457 31.962719265492364 31.889494223002373 31.125886926265288 31.580950890761525 31.67618961370293 31.755662695920574 31.49528368241461 31.551814876284965 31.872563234300472 31.95479772740365 31.3731659738906 31.538344096329602 940.0 674.0 831.0 1056.0 963.0 1107.0 1288.0 983.0 1222.0 1098.0 1162.0 774.0 1404.0 973.0 984.0 894.0 1327.0 1285.0 1124.0 864.0 1245.0 926.0 1242.0 1119.0 11.0 12.0 12.0 13.0 10.0 9.0 12.0 10.0 12.0 14.0 13.0 12.0 11.0 12.0 12.0 11.0 14.0 18.0 12.0 9.0 14.0 11.0 13.0 12.0 -0.12310551001150216 0.3263484733220724 0.4012639356708831 GO:0033013 tetrapyrrole metabolic process biological_process 26.04201380809209 25.88258897258281 22.413475277377767 23.80584623158588 25.73154491160861 23.79773590632421 25.264092541736336 26.33674594928945 25.720695618189875 27.068483439887682 26.42970087595983 26.211721166930023 26.78667968072836 25.51326643133748 25.46108378703633 25.744035258279165 25.68497505808352 25.863417421401596 26.271999997275092 25.94998665225813 25.29450370305984 24.970305516801144 27.17085297179621 25.087897794019252 26.465066512826105 26.73133738117807 27.0 21.0 44.0 40.0 115.0 155.0 141.0 203.0 133.0 136.0 229.0 94.0 110.0 87.0 128.0 122.0 216.0 176.0 121.0 70.0 205.0 108.0 225.0 163.0 3.0 4.0 4.0 3.0 4.0 4.0 4.0 5.0 3.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 5.0 5.0 4.0 3.0 4.0 3.0 4.0 4.0 0.15942483550928088 0.6861059569955559 0.7413508522341591 GO:0033014 tetrapyrrole biosynthetic process biological_process 24.861855151497558 24.68423285887368 21.286137022268164 21.951435368800983 24.60037242307476 22.7208769795214 24.061706208888477 25.26101540678899 24.572918268946573 25.84190940849577 25.312304459295802 25.022912396050447 25.51346656869168 24.077913871383313 24.37256990727117 24.673537382883364 24.537601153358693 24.78790277895635 24.97130295896467 24.672382521527123 24.006114633178925 23.8532508251323 26.08993603653284 23.96931088447499 25.202907943053393 25.465673675500497 11.0 9.0 17.0 18.0 48.0 70.0 60.0 83.0 57.0 56.0 92.0 37.0 52.0 40.0 55.0 56.0 88.0 71.0 48.0 32.0 83.0 47.0 91.0 67.0 2.0 1.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 2.0 2.0 3.0 0.17762229262387663 0.7290344895388041 0.7743276961229171 GO:0033036 macromolecule localization biological_process 27.68685441590653 28.203386657371606 27.673238562978746 28.66397071783436 27.376514584416658 26.436484205868613 27.58348696787184 27.977127930506033 27.33988554178879 27.96756833520012 27.90004068037517 28.371369253338674 28.08696575967637 28.5619513662978 27.690341566948696 27.95590242562373 26.995514594433807 27.22973279262105 27.638342589897967 28.985223190767236 27.11910989300737 27.891490671303238 27.76510109230568 28.023346618000364 28.442133106194746 28.75055644857433 198.0 177.0 190.0 155.0 199.0 178.0 197.0 263.0 257.0 301.0 276.0 205.0 226.0 220.0 194.0 217.0 329.0 277.0 196.0 216.0 216.0 215.0 268.0 339.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.5165322414650753 0.02824036873330045 0.04901805310036017 GO:0033201 alpha-1,4-glucan synthase activity molecular_function 20.907163800929435 19.58675559438472 19.388715229606085 19.40050744090644 20.97114773057743 17.413013163408447 21.143483153913415 20.57278906997494 19.114415701321086 19.40449700117968 21.22372619349364 19.083372833370454 21.670032358187047 18.786847456126203 21.57425598349621 19.72124975455528 20.862310446174646 18.728917975396183 18.608565471144413 19.215848683403095 20.313279295281475 20.740382672365296 18.32389604064885 19.65093434298677 22.289458716945934 19.677051456177466 3.0 4.0 3.0 1.0 5.0 3.0 3.0 2.0 7.0 1.0 9.0 3.0 7.0 2.0 8.0 2.0 4.0 2.0 3.0 3.0 2.0 2.0 12.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.320408206544716 0.05674681648938142 0.08919398863822169 GO:0033218 amide binding molecular_function 26.228267463069162 24.063421674343033 23.89441069570704 22.676496999010876 22.63147785749753 22.4037816959651 26.23220317825768 23.685569837455354 26.649159820881128 24.782078939035525 26.461337832309 23.707392587714573 26.109472169971 23.677273729377546 26.590665584863228 23.78023392436656 26.4522903105545 24.29929150216985 26.804962792180664 25.62157409307329 23.36209906407531 22.71537250409517 27.15196333998749 23.708994622122802 26.609131629610605 24.35057572068564 11.0 10.0 7.0 7.0 22.0 20.0 24.0 32.0 25.0 23.0 40.0 27.0 31.0 23.0 29.0 19.0 32.0 30.0 24.0 17.0 33.0 28.0 31.0 32.0 4.0 3.0 4.0 4.0 4.0 4.0 3.0 4.0 3.0 5.0 5.0 4.0 4.0 5.0 5.0 5.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 5.0 2.1648457887261294 0.005583616806378765 0.012692811975156102 GO:0033293 monocarboxylic acid binding molecular_function 21.531433140240946 23.35137979112689 19.924245266857632 21.64318049691723 19.79533442707616 21.79371343193319 21.525645244314624 23.253977082027678 19.139448543159176 24.64905511203073 19.131775785002986 22.61005108880445 23.375812150910463 23.506443457664986 22.243680430058927 23.48388186689732 21.308823678616086 23.933329997757358 19.68377348931416 22.64032511207343 21.545230154570042 21.98366290939333 22.45732438100912 23.106274658322764 21.0612944269498 24.21084389892695 5.0 8.0 4.0 4.0 5.0 17.0 2.0 30.0 3.0 19.0 18.0 25.0 8.0 20.0 9.0 16.0 5.0 11.0 12.0 14.0 13.0 25.0 11.0 28.0 2.0 1.0 2.0 1.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.8199466508859459 0.0006583371695572323 0.0022696264851033866 GO:0033365 protein localization to organelle biological_process 24.486575702461394 25.37639211209777 24.23906145269484 25.94312842643641 21.362395598738047 NA 25.14861063145037 25.334250044572762 24.10912240040717 25.07586862433052 25.014892069675582 25.491646157891086 25.037315430747572 25.677419887094718 25.125263546529197 24.666789424336706 23.139223339882484 23.695207458606358 23.517622973120236 26.29599595619253 20.08058658367429 24.64749588261044 24.04530052975711 24.35568028852921 25.83101664928544 25.970295175178727 3.0 3.0 7.0 NA 7.0 9.0 10.0 12.0 12.0 21.0 13.0 7.0 10.0 11.0 9.0 7.0 9.0 11.0 2.0 9.0 3.0 5.0 7.0 9.0 2.0 2.0 3.0 NA 4.0 3.0 3.0 3.0 4.0 3.0 5.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 4.0 3.0 -0.8898164096363743 0.022774727854040278 0.04131229703756143 GO:0033554 cellular response to stress biological_process 26.010903765099748 26.0115034262947 25.5631974724996 25.88066503532825 25.338773985556703 26.304962967170443 25.597148219654517 25.704766992702023 25.751830618297912 25.474147658698417 26.141798578413766 26.19100978811889 26.09015907687698 26.22205997132364 25.65058920647599 25.90891197489527 25.425381747891983 25.76983180811121 26.289761976492056 26.16176661904851 27.32440679181932 25.481446377510252 25.595730106237927 26.43262816627898 26.021636163976364 26.220143302873602 81.0 90.0 84.0 133.0 93.0 105.0 139.0 93.0 165.0 128.0 162.0 175.0 101.0 141.0 86.0 120.0 144.0 135.0 83.0 69.0 115.0 170.0 172.0 113.0 3.0 3.0 2.0 3.0 4.0 4.0 3.0 3.0 4.0 3.0 4.0 3.0 4.0 2.0 3.0 2.0 4.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 -0.0005996611949505848 0.2253456937016668 0.2954111614912607 GO:0033692 cellular polysaccharide biosynthetic process biological_process 24.91151586319613 24.45354833587244 25.78590280130889 24.1692824681037 25.122185868874435 23.756439906803323 24.07813368470011 24.850208894250315 23.930680912876202 24.13880305967504 25.030501062900747 24.929522899551216 25.231820290787244 24.961991025991125 25.027218616596052 24.93542356251191 24.527056810013555 23.58459204168841 25.304883108666125 24.54630469832665 24.402343695639768 24.63074711229881 23.578335621742482 23.748666432075357 25.338628830582145 24.258472134698696 20.0 24.0 21.0 16.0 31.0 32.0 33.0 26.0 49.0 29.0 46.0 21.0 40.0 31.0 40.0 28.0 72.0 29.0 27.0 23.0 24.0 17.0 45.0 21.0 3.0 3.0 2.0 4.0 3.0 4.0 3.0 4.0 3.0 3.0 4.0 3.0 3.0 3.0 4.0 4.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 0.45796752732368873 0.0832645166635504 0.12534875367444018 GO:0033817 beta-ketoacyl-acyl-carrier-protein synthase II activity molecular_function 24.65389280166722 25.001242702259702 24.876881163133827 24.435276574245496 24.383366872146553 22.80115368286025 23.577827100122715 25.07038685508081 25.4351442798795 25.73402574985485 24.72012236128109 24.922771202840465 24.417807541100203 25.73293211649248 25.40822360028093 23.787138669842925 24.534334749211478 24.85019430102119 24.63398935187676 25.479559116801273 23.77099149285263 24.106734507631987 23.496068352353035 25.838063392264942 25.066174177396245 24.565865224162913 13.0 7.0 15.0 13.0 15.0 17.0 30.0 19.0 18.0 15.0 17.0 16.0 29.0 14.0 20.0 19.0 27.0 23.0 16.0 15.0 24.0 20.0 24.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.3473499005924836 0.24821307898992373 0.31935043564889154 GO:0033862 UMP kinase activity molecular_function 23.49099092850286 23.492681469173387 22.227687463931822 22.77906962570093 21.59552024478295 23.75385640443099 22.98138446124856 23.47746454337962 23.521770405656532 24.014931597389268 24.059768154548607 24.19469302176491 24.254127908317145 23.57144357090222 23.905200421827445 23.08852740641377 23.79339303850883 23.114989096224484 23.03023444428647 23.64315848611155 23.16406153602876 22.13040512761004 23.27779451651565 23.395898193846488 24.034961397918448 23.661070280030827 8.0 4.0 6.0 6.0 9.0 11.0 10.0 12.0 11.0 11.0 13.0 11.0 15.0 9.0 10.0 9.0 15.0 12.0 13.0 6.0 16.0 10.0 12.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.0016905406705269854 0.9539596927720386 0.9577970205788449 GO:0033865 nucleoside bisphosphate metabolic process biological_process 30.291673466390282 28.768305467765067 28.413630676012573 27.034455179354293 27.89651549332155 27.65114247253931 30.15995348324968 28.930813527342423 30.90843576852625 29.436448548668213 31.002897928152386 28.88016047793283 30.66194683082613 28.354534389677912 30.720009612324823 28.69981132813097 29.897084507091066 28.963653734506412 30.216583779110035 29.161804364562677 29.618789669927892 28.537100941068307 30.45093651286589 28.55008463739077 30.737659067191892 29.423714188368397 350.0 218.0 304.0 222.0 650.0 526.0 756.0 348.0 650.0 460.0 670.0 338.0 666.0 512.0 480.0 434.0 878.0 720.0 486.0 370.0 638.0 450.0 700.0 374.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 1.5233679986252149 0.0022136919545913893 0.006045268182341475 GO:0033866 nucleoside bisphosphate biosynthetic process biological_process 28.095522540860358 26.42412141591689 26.117643112283314 24.99029486499529 25.520419787973555 25.60570335361401 27.979853284171252 26.677449085389586 28.77851641968535 26.82858392041317 28.89038792481032 26.51927237734764 28.46606045224173 26.12868186587169 28.589667006630176 26.46603421212623 27.612792771402113 26.675803892237195 27.98321777913534 26.854857242966446 27.24932298173328 26.242856944983266 28.237563074706834 26.276102707169546 28.488637732296127 26.81569820732307 74.0 52.0 66.0 48.0 144.0 122.0 172.0 78.0 140.0 106.0 146.0 78.0 150.0 112.0 104.0 98.0 202.0 166.0 106.0 84.0 138.0 102.0 154.0 86.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.6714011249434684 0.0032349119169146935 0.007931571851295751 GO:0033875 ribonucleoside bisphosphate metabolic process biological_process 28.936509768731 27.45188812678728 27.085143908298235 25.63384242416749 26.58781738261881 26.250938783015908 28.80027747043147 27.59122300330328 29.53422874264077 28.177951262014908 29.62349494933873 27.56781018277333 29.306709281328764 27.007553312096785 29.345927900372075 27.3549774125626 28.565591883503274 27.63307879727184 28.87163884016325 27.836106592846303 28.30850543456958 27.208168012300682 29.100543669840192 27.215916823626237 29.396913695069948 28.165246600121108 138.0 83.0 119.0 87.0 253.0 202.0 292.0 135.0 255.0 177.0 262.0 130.0 258.0 200.0 188.0 168.0 338.0 277.0 190.0 143.0 250.0 174.0 273.0 144.0 3.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 1.4846216419437184 0.0022136919545913893 0.006045268182341475 GO:0033920 6-phospho-beta-galactosidase activity molecular_function 19.582838517800905 20.381051999363105 21.28396785385757 19.2390734046052 21.21241903258776 NA 17.720947941210394 20.179078814751684 NA NA 19.11516780513706 20.149890025405913 19.269184268498968 18.665432000699813 19.21365305588056 22.220743027010045 17.57740316620523 17.818366643471734 18.981703450172912 NA 18.88576887397117 NA 13.96154834753988 20.008635722024408 18.67156222197789 NA 7.0 4.0 7.0 NA 1.0 3.0 NA NA 4.0 6.0 3.0 3.0 3.0 9.0 1.0 2.0 2.0 NA 2.0 NA 1.0 4.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7982134815622004 0.22146183835692945 0.2921610721664355 GO:0033926 glycopeptide alpha-N-acetylgalactosaminidase activity molecular_function 22.505335184012395 20.870697029561352 22.877609994546628 21.06992926011358 23.114225161296353 NA 21.403085977095056 20.541116002999075 18.014813839716073 20.919882801736303 21.9906453159656 21.492999681566047 21.20961375760041 20.306045548937465 21.702008454598264 20.785527142537656 21.450349373149148 20.91878061774553 24.292323302898268 21.26564242887738 22.5225364519416 20.39221589278037 22.6941212693978 18.72677010710332 22.36277095044757 21.52197839672666 15.0 9.0 16.0 NA 6.0 6.0 2.0 10.0 9.0 10.0 7.0 6.0 11.0 10.0 10.0 9.0 16.0 10.0 10.0 7.0 9.0 3.0 11.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.6346381544510429 0.0031348505814530626 0.007931571851295751 GO:0033993 response to lipid biological_process 18.696578774088376 21.95376802813304 17.041541616741096 21.215515926602414 14.802535732482758 21.4531044018516 16.19463320873981 21.85520971241421 19.39669951353797 21.843828761187762 20.7637050754652 22.70712252864921 14.889243061109436 20.724190290592045 NA 21.445661817994075 18.0178046006368 23.32709062988541 18.161380949769033 22.189294848181486 NA 19.599950495276754 19.61272291913899 22.935393263326787 17.183086880705268 18.301723201613555 2.0 6.0 2.0 2.0 2.0 6.0 4.0 2.0 4.0 8.0 2.0 8.0 NA 4.0 4.0 8.0 4.0 6.0 NA 2.0 4.0 12.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 -3.2571892540446648 0.00036993149163163074 0.0014703009603703032 GO:0034030 ribonucleoside bisphosphate biosynthetic process biological_process 27.095522540860358 25.42412141591689 25.117643112283314 23.99029486499529 24.520419787973555 24.60570335361401 26.979853284171238 25.677449085389586 27.77851641968535 25.82858392041317 27.89038792481032 25.51927237734764 27.46606045224174 25.12868186587169 27.589667006630176 25.46603421212623 26.612792771402113 25.675803892237195 26.98321777913534 25.854857242966446 26.24932298173328 25.242856944983266 27.237563074706827 25.276102707169546 27.488637732296127 25.81569820732307 37.0 26.0 33.0 24.0 72.0 61.0 86.0 39.0 70.0 53.0 73.0 39.0 75.0 56.0 52.0 49.0 101.0 83.0 53.0 42.0 69.0 51.0 77.0 43.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 3.0 2.0 3.0 2.0 1.6714011249434684 0.0032349119169146935 0.007931571851295751 GO:0034032 purine nucleoside bisphosphate metabolic process biological_process 28.936509768731 27.45188812678728 27.085143908298235 25.63384242416749 26.58781738261881 26.250938783015908 28.80027747043147 27.59122300330328 29.53422874264077 28.177951262014908 29.62349494933873 27.56781018277333 29.306709281328764 27.007553312096785 29.345927900372075 27.3549774125626 28.565591883503274 27.63307879727184 28.87163884016325 27.836106592846303 28.30850543456958 27.208168012300682 29.100543669840192 27.215916823626237 29.396913695069948 28.165246600121108 138.0 83.0 119.0 87.0 253.0 202.0 292.0 135.0 255.0 177.0 262.0 130.0 258.0 200.0 188.0 168.0 338.0 277.0 190.0 143.0 250.0 174.0 273.0 144.0 3.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 1.4846216419437184 0.0022136919545913893 0.006045268182341475 GO:0034033 purine nucleoside bisphosphate biosynthetic process biological_process 27.095522540860358 25.42412141591689 25.117643112283314 23.99029486499529 24.520419787973555 24.60570335361401 26.979853284171238 25.677449085389586 27.77851641968535 25.82858392041317 27.89038792481032 25.51927237734764 27.46606045224174 25.12868186587169 27.589667006630176 25.46603421212623 26.612792771402113 25.675803892237195 26.98321777913534 25.854857242966446 26.24932298173328 25.242856944983266 27.237563074706827 25.276102707169546 27.488637732296127 25.81569820732307 37.0 26.0 33.0 24.0 72.0 61.0 86.0 39.0 70.0 53.0 73.0 39.0 75.0 56.0 52.0 49.0 101.0 83.0 53.0 42.0 69.0 51.0 77.0 43.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 3.0 2.0 3.0 2.0 1.6714011249434684 0.0032349119169146935 0.007931571851295751 GO:0034220 ion transmembrane transport biological_process 28.358859197207128 29.23975236327794 28.04428181452693 28.476353558238586 27.699831057570325 29.080458786883764 27.97995146705573 29.278974027951204 28.172017011276328 29.200081436290642 28.45955688550024 29.33101273522077 28.468217072339677 28.73401079545608 28.140612953908292 29.703503794765663 28.061360728751588 29.608063197955083 29.044311499792 29.22881249882412 28.882520098959784 29.11868810960249 28.4305347497639 29.364838146381263 28.350191012779607 29.341272830652283 213.0 195.0 203.0 263.0 215.0 272.0 264.0 275.0 250.0 276.0 255.0 200.0 271.0 269.0 186.0 268.0 289.0 315.0 264.0 256.0 256.0 212.0 253.0 302.0 3.0 2.0 2.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 -0.8808931660708126 8.637667594722788e-05 0.0006159890947550879 GO:0034248 regulation of cellular amide metabolic process biological_process 27.658614772314863 27.98800095998281 27.7528679490337 27.582227987953768 27.669639475408612 28.217872397207607 27.401280412929392 28.26255199683576 27.49864219722461 27.92610508791517 27.604758079248427 28.109186481649946 27.599397082084646 27.91785741816524 27.743126946987605 27.87470337622575 27.27044306873933 27.83854209143366 28.081412783480737 28.271667343940273 27.74080103017557 27.83980262549108 27.67861647857361 27.81843404338259 27.704710188009805 28.03038269763389 77.0 69.0 72.0 90.0 78.0 106.0 96.0 102.0 105.0 112.0 93.0 78.0 87.0 113.0 75.0 107.0 124.0 111.0 91.0 76.0 87.0 101.0 93.0 112.0 2.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 2.0 3.0 2.0 2.0 3.0 3.0 3.0 2.0 2.0 -0.3293861876679465 0.0012242832644312096 0.0037265988146589013 GO:0034311 diol metabolic process biological_process 22.34979455224564 22.73887603586727 21.333639364922746 NA NA 19.083467044728238 22.518091417955688 22.97870010683492 22.03986295217509 23.67207061056561 20.782342285557608 22.57986669020319 22.372653651621302 24.030676848140068 22.15148778933091 21.96226150377017 22.790476104021767 22.89720199943203 23.10054801192421 22.182843619845876 20.865212531077173 21.763703833734727 23.467170756973424 21.43012414661077 21.997652076335253 22.99476297999751 3.0 NA NA 2.0 3.0 5.0 6.0 4.0 3.0 5.0 3.0 5.0 3.0 5.0 3.0 5.0 9.0 3.0 3.0 4.0 3.0 5.0 3.0 6.0 2.0 NA NA 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 4.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 4.0 -0.38908148362163075 0.45016041088680303 0.5347630423627702 GO:0034404 nucleobase-containing small molecule biosynthetic process biological_process 28.82864297975997 30.00960607866929 29.45910306605968 29.58123880222932 29.31668652821752 30.105473557346397 28.145717839475683 30.23954583697319 27.68696761339278 29.81604685718472 28.54675129776539 29.710393856342808 28.687657299602066 29.559124973141078 29.45061864602248 30.331060053220487 28.17069853649989 30.42165307635416 29.51678530453486 30.2973067880846 28.82607472441699 29.888476906503893 28.21289466558849 30.04148665464529 28.522983905347 29.781570787330555 244.0 267.0 290.0 346.0 234.0 408.0 253.0 369.0 255.0 339.0 272.0 264.0 306.0 347.0 214.0 368.0 403.0 370.0 325.0 332.0 257.0 330.0 235.0 367.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.18096309890932 3.225641456243767e-05 0.0005099643033035255 GO:0034470 ncRNA processing biological_process 25.08528754733395 26.57265174504268 25.51632775054317 26.14076730585591 25.032710220387216 26.36056457774884 24.17552252447945 26.723804161217622 25.00067581195406 26.180407597475075 25.4526417532378 26.41423792093889 25.52759353933999 27.01288696543117 25.426251136764865 26.73511857173436 23.754912899619843 26.657843707143137 25.287005834659535 26.640458704719357 25.079339493360628 26.17862326894165 24.95316140527593 27.24400945814629 24.835134369353447 26.03410056654395 82.0 137.0 80.0 161.0 67.0 160.0 60.0 138.0 114.0 159.0 109.0 135.0 76.0 187.0 52.0 180.0 119.0 134.0 83.0 134.0 65.0 193.0 95.0 136.0 3.0 4.0 3.0 3.0 3.0 4.0 2.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 2.0 4.0 3.0 3.0 3.0 3.0 2.0 4.0 3.0 4.0 -1.4873641977087289 3.225641456243767e-05 0.0005099643033035255 GO:0034613 cellular protein localization biological_process 24.85178787065177 25.43998077701044 24.328908080679717 25.94312842643641 21.400217138184928 NA 25.27045231476782 25.378222415505114 24.25310082892907 25.18367047772232 25.28547902321995 25.6354177267796 25.32176085142743 25.70551557259883 25.184490198984186 24.765548980479732 24.010259550490822 23.837238086787444 24.858863097268696 26.36814860746915 23.34096016705148 24.71364815140769 24.76883368399133 24.40905455488504 26.092059295831962 26.013065755970025 6.0 3.0 9.0 NA 12.0 12.0 13.0 16.0 19.0 30.0 19.0 9.0 14.0 15.0 16.0 9.0 39.0 15.0 7.0 12.0 9.0 6.0 14.0 14.0 2.0 1.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.588192906358671 0.12389131916687696 0.17411752963993518 GO:0034622 cellular protein-containing complex assembly biological_process 26.36240978948303 27.16791528194769 26.661332581824425 26.723689091216244 26.29548973085668 26.612145194287177 25.232272767162122 27.35867967834239 26.2765075527909 27.185423072863788 25.562821327725025 27.315521619391895 26.03952114785184 26.959075607532483 26.936609583593178 27.534371274692006 25.758365453431438 27.261246898583174 26.691808247403824 27.58392068530509 26.61049069410268 26.814167734077905 27.18300660573021 27.23373762886612 25.816674135103806 27.07667575701148 44.0 20.0 29.0 54.0 38.0 42.0 36.0 42.0 50.0 45.0 43.0 29.0 61.0 49.0 36.0 47.0 67.0 52.0 51.0 34.0 57.0 43.0 41.0 46.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 2.0 2.0 4.0 2.0 3.0 2.0 3.0 3.0 2.0 2.0 2.0 3.0 3.0 -0.8055054924646576 0.00034415785384659113 0.0013990521224773477 GO:0034641 cellular nitrogen compound metabolic process biological_process 35.6809382063177 36.33907587894566 35.736398381147936 35.71776740569403 35.390467279463834 36.27979338262296 35.29560677122233 36.502102663040034 35.33482066079827 36.23947287110082 35.84887423733236 36.25472885389892 35.80513815066729 35.91725637928909 36.081913662986864 36.69304817215032 35.231486507681346 36.73428810969807 36.261574979126415 36.53558744255143 35.610733167397385 36.204572856293524 35.54544468835902 36.450893741766755 35.631672390619094 36.21383744157895 25886.0 25346.0 24724.0 31372.0 28736.0 40031.0 32787.0 37089.0 33554.0 37691.0 35828.0 28740.0 36528.0 37801.0 28353.0 38482.0 44495.0 42368.0 32657.0 31666.0 34242.0 35314.0 34406.0 37981.0 11.0 12.0 10.0 11.0 11.0 11.0 11.0 11.0 10.0 11.0 11.0 12.0 11.0 11.0 10.0 11.0 11.0 12.0 9.0 9.0 10.0 11.0 11.0 12.0 -0.6581376726279586 0.00042856814449695465 0.0016457016748683058 GO:0034645 cellular macromolecule biosynthetic process biological_process 31.10201853205773 30.682655034993097 30.338487205854964 30.035588260645298 29.89832238962705 30.582759583789702 30.62739524101305 30.77049828007069 31.230778972573603 30.466545854791303 31.24094548818339 30.938389466683606 31.26018000125505 30.622773723320012 31.44375053248612 30.899399206753287 30.720878626552 30.467086199495768 31.82171559254025 31.050042714544322 30.91976757477207 30.41862852848421 31.648244910625124 30.892285535978022 30.986882411580247 30.75151782295726 801.0 592.0 541.0 857.0 828.0 905.0 1089.0 842.0 1075.0 974.0 1020.0 754.0 1294.0 884.0 848.0 815.0 1364.0 1227.0 896.0 618.0 1087.0 842.0 948.0 924.0 7.0 5.0 7.0 6.0 6.0 7.0 6.0 6.0 7.0 7.0 7.0 7.0 7.0 6.0 7.0 6.0 7.0 6.0 7.0 6.0 6.0 6.0 7.0 6.0 0.4193634970646336 0.04964722965745621 0.07872902492059129 GO:0034654 nucleobase-containing compound biosynthetic process biological_process 32.23809344999288 33.04789735065553 32.405225381610805 32.44475155641872 32.05508088906745 32.96318942308289 31.90006689216984 33.21648387037377 31.77492677989755 32.97531248576079 32.400871505141396 32.962918111861875 32.39828707980907 32.63128057685492 32.56182426112343 33.40232022425669 31.792932962637874 33.44496977319501 32.7946778078673 33.218669873843865 32.24950762148871 32.90600378857352 31.951352400892638 33.1704165660805 32.17676032582977 32.92117436939516 2772.0 2794.0 2652.0 3287.0 2980.0 4320.0 3314.0 4051.0 3456.0 4095.0 3752.0 3147.0 3714.0 4071.0 2981.0 4205.0 4688.0 4528.0 3454.0 3448.0 3546.0 3845.0 3608.0 4174.0 7.0 6.0 7.0 6.0 6.0 7.0 6.0 6.0 7.0 7.0 7.0 7.0 7.0 6.0 7.0 6.0 7.0 6.0 7.0 6.0 6.0 6.0 7.0 6.0 -0.8098039006626507 6.784570247173055e-05 0.0005498145239267514 GO:0034655 nucleobase-containing compound catabolic process biological_process 28.623642254670823 29.705668399861192 29.186722336910172 29.088791329589892 29.00265091639757 29.811444378995038 28.00503442894245 29.984099270321607 27.60525426733529 29.529862779475113 28.43156529718683 29.43838534544748 28.3263888646741 29.08187225168767 29.35678500821074 30.09128742597519 27.958165192003023 30.253701539861012 29.450483976226764 29.951020690641688 28.43776030936831 29.58231900442257 27.93052774726961 29.694842451193608 28.34410866150225 29.43577837038769 176.0 178.0 180.0 247.0 195.0 294.0 210.0 246.0 211.0 254.0 195.0 194.0 239.0 252.0 163.0 275.0 342.0 281.0 208.0 208.0 217.0 247.0 198.0 239.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.082026145190369 0.00021985068263840352 0.0009941074345388681 GO:0034660 ncRNA metabolic process biological_process 28.79184126535464 29.502884387258764 28.27298764859236 29.019560693566824 28.211383730607864 29.56258154274683 28.5564982910588 29.44116998170957 29.3179230152235 29.03202123532583 29.297720037664057 29.50271944975492 29.10293370945632 29.580268935502 29.041606223192183 29.872770073266125 28.253179251654025 29.399698754404856 28.910460400622405 29.70963044235538 28.225222510658455 29.300287232050838 28.78033363640482 29.998550800056186 28.86610156647973 29.270986610148217 448.0 607.0 449.0 739.0 626.0 811.0 722.0 788.0 843.0 840.0 825.0 663.0 746.0 889.0 531.0 896.0 949.0 881.0 549.0 729.0 721.0 908.0 755.0 811.0 4.0 4.0 3.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 -0.7110431219041224 0.00042856814449695465 0.0016457016748683058 GO:0035383 thioester metabolic process biological_process 28.929893481423626 27.41873529751685 27.05356480039801 25.54803978834419 26.55699110292264 26.151972036061725 28.79716114667965 27.57629774188209 29.52600086018853 28.167745553848306 29.619374314286237 27.544179787425605 29.298685731365552 26.914212613400803 29.343187474789254 27.307870483861308 28.558686542877048 27.597442689442104 28.867485867375496 27.810389737790594 28.30688040380181 27.191423528647967 29.093925633997078 27.15236581754251 29.388913026701765 28.153179339976106 132.0 73.0 111.0 74.0 246.0 190.0 270.0 124.0 244.0 166.0 242.0 104.0 250.0 173.0 178.0 150.0 328.0 264.0 186.0 134.0 238.0 156.0 254.0 132.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.511158183906776 0.0022136919545913893 0.006045268182341475 GO:0035556 intracellular signal transduction biological_process 24.151723241650995 21.868316352792156 21.31249302217822 20.75052444014234 20.59152723894432 20.50770745507435 24.04676340569951 21.284660603915395 25.216703645743593 21.4565118814388 24.814907540275076 21.1737912180668 24.79714192919845 23.341586409979172 24.973555984329945 21.724711344132814 22.74678606092742 21.271674905044463 23.946758861866932 23.071204155134048 20.983303583072704 18.47494073802112 23.83859115410291 22.59057032622199 24.89742050938555 21.40026564963181 9.0 7.0 6.0 9.0 20.0 12.0 30.0 9.0 32.0 11.0 30.0 16.0 37.0 21.0 15.0 11.0 35.0 20.0 6.0 4.0 27.0 18.0 28.0 12.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 1.0 1.0 1.0 1.0 2.0 2.0 3.0 2.2834068888588384 0.009374768459434895 0.01937038251220985 GO:0035639 purine ribonucleoside triphosphate binding molecular_function 31.059919779933395 30.908516115769768 30.306654815387958 30.24556709639422 30.258851804790893 31.038496841322075 30.819199328361172 31.03791863850341 31.22376687956137 30.831503451623828 31.383840680390392 31.02344854245069 31.180876602754182 30.639055500348306 31.116884934581986 30.978078514368228 30.642954646767286 30.837499614651136 31.652219405152763 31.144257000659064 31.247491162510386 30.976575409310907 31.143918460473643 30.93972428406623 31.104413481608205 31.007032727349817 776.0 823.0 726.0 1061.0 1151.0 1291.0 1385.0 1208.0 1403.0 1227.0 1362.0 1013.0 1441.0 1236.0 1053.0 1250.0 1778.0 1565.0 954.0 994.0 1306.0 1213.0 1316.0 1251.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.15140366416362738 0.11903289845700783 0.16804644488048165 GO:0035821 modification of morphology or physiology of other organism biological_process 25.43409789334623 25.563815891658386 24.948592388747787 25.29915800626733 20.433731193242085 22.235211704517575 25.62290981274966 25.29398026632859 25.40651875725128 25.85978706107911 26.681768590050375 26.83660881631796 25.30732661745568 26.20317823707991 NA 22.630129441169448 25.827186084812002 25.065892806133977 25.471820026440266 26.36126087162548 21.380009610992893 NA NA 24.54295588738138 25.963440922272873 25.515646785893487 15.0 15.0 15.0 15.0 15.0 31.0 54.0 15.0 15.0 40.0 15.0 25.0 NA 30.0 15.0 30.0 15.0 15.0 15.0 NA NA 30.0 15.0 15.0 2.0 2.0 2.0 2.0 2.0 2.0 4.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 NA NA 2.0 2.0 2.0 -0.1297179983121559 0.8879996937548637 0.9166448451663108 GO:0035999 tetrahydrofolate interconversion biological_process 26.392922129606706 25.248886292541684 25.35494180336705 25.19094466669465 25.318214757974285 23.99266029961707 26.229396053037977 24.88031627042969 26.66551155989289 25.13335891239072 27.02443605937109 25.69602192147991 26.24722309535833 25.40597301918593 26.60799047479577 24.99593020256882 26.27295938303984 24.60171372574119 26.756836040819216 26.459077068367854 25.409342774660267 24.9675211638979 26.921631776423826 24.61380114794491 26.61700436493017 25.49580151524957 35.0 33.0 35.0 34.0 47.0 46.0 47.0 51.0 52.0 45.0 54.0 31.0 63.0 38.0 38.0 36.0 55.0 58.0 55.0 39.0 40.0 29.0 53.0 48.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.1440358370650223 0.0008121171348941295 0.002709952364566507 GO:0036094 small molecule binding molecular_function 33.45538284694362 33.302609554269345 32.90795710122316 32.62223369751699 32.87878133804819 33.383445185805925 33.24134975605488 33.42388463063758 33.52021714385913 33.301670418414965 33.67852412605069 33.37071341201282 33.50467512709436 32.947094604058435 33.57200796274068 33.374942835906985 33.08764828033563 33.26281891237565 34.029547060893194 33.54313479575942 33.6843099694848 33.42736173233985 33.49007692698357 33.242076458747576 33.442032408723215 33.49988184329819 3174.0 3045.0 2821.0 4000.0 4553.0 4987.0 5454.0 4746.0 5531.0 4849.0 5301.0 3858.0 5738.0 4742.0 4264.0 4840.0 6915.0 6075.0 3950.0 3862.0 5191.0 4623.0 5188.0 4924.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 5.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 6.0 6.0 5.0 5.0 5.0 4.0 5.0 5.0 0.15277329267427575 0.16585666034291002 0.2267131567447445 GO:0036381 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity molecular_function 24.08391761263484 22.618189487400198 NA 21.27658974904632 22.40939958828593 22.538950074507532 23.352735754590306 22.366326520226426 25.591093308545343 23.086154619904857 25.169442041149626 21.88911324326209 23.293867886167067 23.347399767136746 25.540334825959864 23.75610512542384 23.213177658515438 22.30776129046947 17.02302486414763 22.011011947807642 20.02167028678058 19.58902300096712 23.526888278718356 23.412518797787534 23.09295201842368 22.006854529169026 NA 8.0 9.0 9.0 10.0 10.0 13.0 8.0 12.0 10.0 9.0 11.0 16.0 16.0 7.0 10.0 2.0 8.0 4.0 4.0 15.0 13.0 10.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.4657281252346408 0.10955657678268572 0.15625898037119063 GO:0038023 signaling receptor activity molecular_function 22.857452887580465 24.107115706251 20.205550921287127 24.635959121444092 21.799114395557666 22.822357663836666 23.12385058898169 23.83149319768655 21.84505749816738 23.17742119238168 23.59042717302103 23.80407823639394 24.45789723611397 24.6629611864774 20.51395316775568 24.81457887253509 21.34437384450316 23.422309753192824 19.67121878008593 23.72226174948389 22.87937937251147 22.377170601887606 23.574160837986998 25.288153341257424 23.58145187134979 23.99528557924902 6.0 29.0 5.0 15.0 14.0 25.0 9.0 26.0 15.0 24.0 14.0 31.0 8.0 24.0 8.0 24.0 6.0 24.0 5.0 17.0 11.0 33.0 16.0 31.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.2496628186705365 0.005583616806378765 0.012692811975156102 GO:0042026 protein refolding biological_process 27.890358010718607 28.69039210005371 27.058092649380754 27.978021389060828 26.154192313717274 27.943819323499287 27.750796738237323 28.68455693356761 26.907178120544753 29.05963352701141 27.526105863008283 28.794675513102806 27.9823189658612 28.626375229075546 27.27206449081964 28.799290364195947 27.45892931209625 28.35093814981307 30.02058985274257 29.44520116077827 27.50084522159812 28.37956483185303 27.295564426121178 27.94849292226345 27.345514983826927 29.288935914554358 76.0 43.0 55.0 83.0 97.0 75.0 121.0 97.0 113.0 102.0 123.0 52.0 128.0 84.0 101.0 72.0 140.0 146.0 104.0 91.0 97.0 84.0 99.0 118.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.800034089335103 0.0009986863791802587 0.0031633517797384847 GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity molecular_function 20.47534478670916 21.99502820429472 20.705834976526667 21.3830781949611 19.6134069075922 22.1180912405628 19.054839499101863 22.45801166349466 20.413659589825002 21.898251726579307 20.573539432315755 21.6726974961612 22.071281349167666 22.08499804770133 16.465790883882512 22.816138934382554 19.638139093831164 22.496203882490626 17.337211845611375 21.720832333276206 NA 21.182079678952284 21.244919708414983 22.464464467567097 20.972389323878886 18.889469421629148 5.0 6.0 5.0 12.0 2.0 11.0 7.0 10.0 6.0 7.0 8.0 14.0 1.0 17.0 2.0 16.0 1.0 7.0 NA 9.0 2.0 20.0 8.0 3.0 2.0 1.0 1.0 1.0 1.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 1.0 1.0 2.0 NA 1.0 1.0 2.0 2.0 1.0 -1.5196834175855578 0.0016962207449685985 0.0049575725754585735 GO:0042133 neurotransmitter metabolic process biological_process 26.002677274740787 26.125529817646164 25.74109655184578 25.81515336994671 26.70043165022821 25.71243398336048 25.35018471368891 25.286382347411198 24.81143217868185 26.201373372574825 26.13495514686036 26.2759638740491 25.603656179724606 26.26924923120141 25.316273833982372 25.54290321891461 23.832041986092644 24.96273175092772 27.468275920686413 27.851700540181746 26.565169794074148 25.531684253652987 25.961384465884052 25.40085602218211 25.169910168998147 26.01207077033493 52.0 43.0 111.0 102.0 61.0 70.0 74.0 99.0 77.0 64.0 74.0 51.0 66.0 54.0 43.0 54.0 164.0 117.0 150.0 50.0 64.0 46.0 60.0 65.0 4.0 3.0 4.0 3.0 4.0 4.0 5.0 4.0 5.0 3.0 4.0 4.0 4.0 3.0 4.0 3.0 5.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 -0.1228525429053775 0.6441672226837103 0.7073013587238495 GO:0042168 heme metabolic process biological_process 21.277209293396663 22.161043882986974 18.445181226146953 NA 16.344529394019865 NA 19.38464041208457 21.466915792891378 21.013826541299906 23.29168443267292 18.682416957166048 22.534674144965358 23.020459354505128 21.478456251639557 17.52545470837626 21.022459842313488 20.779072922528254 20.850909277962284 21.58383380700518 22.330058934393463 21.267812396655184 19.63508542041588 22.157853996577096 20.490918138577076 22.514265748371415 23.64856772011838 4.0 NA 1.0 NA 6.0 10.0 11.0 18.0 7.0 14.0 23.0 10.0 2.0 4.0 12.0 6.0 12.0 20.0 9.0 4.0 24.0 8.0 22.0 18.0 2.0 NA 1.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.883834589590311 0.11353247591183233 0.16174489718945975 GO:0042180 cellular ketone metabolic process biological_process 25.163168787008228 27.153274887955106 23.93943344450736 27.06043535924127 27.54877108549244 28.00730442415896 22.564358636405412 26.26172589600005 23.03020763996723 26.53131621655784 22.860364850999645 24.85463306778556 24.854914538521786 26.364770966854 21.445879230385614 27.723358952740913 23.149484661942026 27.311906155449677 24.892174028361893 27.57211578031427 26.59792404294692 27.341953086870816 23.6891524047368 27.31416836142633 24.703387076321512 27.275445791551213 19.0 28.0 32.0 46.0 11.0 44.0 15.0 38.0 21.0 23.0 24.0 26.0 5.0 48.0 8.0 37.0 75.0 30.0 34.0 41.0 16.0 30.0 23.0 34.0 4.0 3.0 3.0 5.0 4.0 5.0 4.0 5.0 5.0 5.0 4.0 3.0 4.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 4.0 4.0 4.0 6.0 -1.9901061009468783 0.0009986863791802587 0.0031633517797384847 GO:0042219 cellular modified amino acid catabolic process biological_process 20.70233234640959 21.62498617967106 19.94113959091284 NA NA 20.13870228335554 18.640937888333887 22.033940519237067 20.965257568452454 22.611584585396038 19.832689277784635 22.065009270789922 21.456448630166665 21.241040453703032 20.052385491384626 21.31536829164773 20.01215624328968 21.741015139271145 20.73368818906923 21.063135843010468 20.06805760065568 20.497878359330183 22.196246526758895 20.97650610857601 20.697676650795703 22.254508976981654 5.0 NA NA 1.0 2.0 10.0 10.0 14.0 5.0 12.0 8.0 8.0 3.0 9.0 5.0 9.0 6.0 9.0 4.0 5.0 9.0 6.0 8.0 12.0 1.0 NA NA 1.0 1.0 1.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 1.0 2.0 1.0 2.0 2.0 1.0 2.0 2.0 -0.9226538332614673 0.009493054145363056 0.019582366237046435 GO:0042221 response to chemical biological_process 24.691702929676854 24.970470817378626 20.75034243250865 24.072590165204506 22.137462890894952 25.11589100467802 24.45694913676619 24.88705950664943 25.24420269769761 24.720611270881953 25.36753812927865 25.570691745810844 24.470536648447 23.965166946744546 25.68081210101757 24.398490277593325 24.00895235868566 26.200562074979874 25.99286146170095 25.37053102117544 20.719151554085013 22.49595036560278 24.510501238717985 25.94980418897477 24.6550805945138 21.10907812367116 18.0 43.0 23.0 37.0 31.0 52.0 54.0 22.0 51.0 60.0 32.0 63.0 34.0 35.0 47.0 65.0 118.0 66.0 4.0 16.0 48.0 109.0 36.0 14.0 4.0 3.0 4.0 4.0 5.0 5.0 5.0 4.0 5.0 4.0 5.0 4.0 5.0 4.0 4.0 3.0 7.0 6.0 3.0 4.0 5.0 6.0 5.0 2.0 -0.27876788770177185 0.5253727863737021 0.6008633207515945 GO:0042254 ribosome biogenesis biological_process 25.31971180637352 25.80571407248821 24.329548821505906 25.571312340075607 23.886703270365572 25.156878497330585 25.024480010013036 26.02459137241893 25.42538819065064 25.751639916543546 25.224934365338488 26.20015782300645 24.893436738792683 25.389770384712488 25.603417503880873 25.728458240878968 24.67877881955317 25.86926146650353 26.83619642257675 26.36905266370165 24.77947246586046 25.722422824242734 25.756918429200105 25.904200431695557 24.9860143257451 25.547350230505586 39.0 41.0 28.0 47.0 27.0 54.0 30.0 45.0 39.0 51.0 37.0 34.0 41.0 44.0 33.0 52.0 42.0 65.0 40.0 43.0 32.0 48.0 35.0 48.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4860022661146921 0.007911788680711459 0.016907384030013527 GO:0042274 ribosomal small subunit biogenesis biological_process 22.004327007231726 23.66761737720884 23.511800656515497 23.511947711292315 22.65891493221137 23.79447662376261 20.41580023234261 23.926168335524913 21.622413377319475 23.223928450657016 21.18859671085875 23.75604545144907 21.936794927527647 23.66506980300135 21.37273395712589 23.846310160634193 21.36467199422977 22.995667750744357 22.424190872850566 23.605743704228072 21.669259804479843 23.51981881034277 21.429394957804448 24.308928788954677 21.805403917403808 23.411755926754577 21.0 22.0 16.0 21.0 6.0 29.0 10.0 20.0 9.0 23.0 13.0 23.0 10.0 28.0 7.0 19.0 16.0 25.0 13.0 21.0 5.0 30.0 13.0 27.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.663290369977112 6.784570247173055e-05 0.0005498145239267514 GO:0042278 purine nucleoside metabolic process biological_process 27.551116900215746 28.47029540467868 27.72112232123285 28.44240994277676 28.115463726505155 28.443316894591874 26.88863227513588 28.49087934262443 26.61548986741167 28.15243194500288 27.193479539976373 28.173193106364145 27.956270990609717 28.56504521198532 27.00896280726232 28.491855861099342 27.010513285606827 28.27622587000093 27.673031745387306 28.952344321942896 28.112827766615286 28.242831358121837 27.863980154920288 28.62282826998721 27.486724014141625 28.591580584986595 193.0 170.0 226.0 280.0 153.0 301.0 210.0 296.0 194.0 270.0 259.0 211.0 200.0 290.0 154.0 298.0 267.0 253.0 276.0 253.0 233.0 247.0 200.0 321.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.9191785044629341 3.225641456243767e-05 0.0005099643033035255 GO:0042286 glutamate-1-semialdehyde 2,1-aminomutase activity molecular_function 21.185392034327954 20.175894258225647 16.811719292074706 NA 19.399239680226053 18.304169454505626 21.189021958497435 20.453134109640544 20.604492766449727 20.817644262667283 21.58174455873695 20.114220550641786 21.5548015454512 18.54053993174123 20.273572923396724 19.06934215359692 21.713574631926733 20.220731984908703 22.35206212716218 20.017425877801248 20.790491179559904 20.73682063129472 21.043306281174573 18.82744950298968 21.76789602779064 21.447761328620125 1.0 NA 2.0 1.0 4.0 5.0 3.0 4.0 4.0 4.0 4.0 2.0 1.0 3.0 6.0 4.0 11.0 6.0 5.0 2.0 6.0 3.0 6.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0094977761023074 0.022774727854040278 0.04131229703756143 GO:0042355 L-fucose catabolic process biological_process 23.127149340140186 22.163663460689783 23.055595550634433 18.792587555152682 23.90298186591092 20.09251732740204 23.042433959791666 19.89352706097764 21.80950109595901 20.53121560453136 23.354406825447864 21.398548826649037 22.5334128042528 NA 23.68921999099398 23.21232511383565 23.3663634091639 NA 24.40106732700841 23.25156814427125 21.736171360131728 21.680841353745915 21.39473332147751 23.403353658112678 21.81117740308895 22.51507244341936 13.0 4.0 16.0 4.0 12.0 5.0 8.0 7.0 13.0 8.0 17.0 NA 27.0 14.0 21.0 NA 14.0 12.0 11.0 8.0 8.0 11.0 7.0 10.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.9634858794504026 0.0409456971929358 0.06795243363934027 GO:0042364 water-soluble vitamin biosynthetic process biological_process 25.63904322724968 24.730239611929086 21.372693251465254 23.377256941030826 24.54326959190231 23.746142022492823 24.30797474103624 25.329406795459317 25.38308339532115 25.49736735584648 25.666989733989038 24.80458010404726 25.33562234521089 23.92793512658156 26.56611365483653 25.191679900167518 24.647061691428753 25.03419368505188 27.39944977891625 24.663780273144663 23.77761374898934 23.86246118289328 26.208016316779524 24.669952983744512 25.42907227829909 24.976906402025488 14.0 25.0 12.0 32.0 54.0 76.0 66.0 67.0 63.0 56.0 77.0 41.0 62.0 66.0 56.0 68.0 92.0 69.0 41.0 34.0 80.0 75.0 95.0 57.0 4.0 5.0 5.0 4.0 7.0 5.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 5.0 7.0 5.0 7.0 6.0 5.0 4.0 6.0 7.0 7.0 6.0 0.9088036153205934 0.18420928818665294 0.2488021554728819 GO:0042398 cellular modified amino acid biosynthetic process biological_process 25.31759531995345 22.4944672994696 20.421167125471907 22.64935002547353 18.14455589802972 21.61842503118652 22.478356708219568 22.086463717724826 21.663938820319068 21.86674870614478 23.616478756756788 22.46378076967158 22.437722333179305 23.160573232311915 27.087797154428586 21.97179995668123 22.82776355765297 21.10528414954949 28.16723390322693 22.80858930065111 19.010167600320344 NA 23.17166954525879 23.463486277862486 23.38017135447989 22.627474666189862 8.0 7.0 3.0 12.0 10.0 20.0 11.0 14.0 12.0 13.0 10.0 14.0 18.0 19.0 7.0 11.0 25.0 23.0 8.0 NA 13.0 24.0 17.0 15.0 1.0 2.0 2.0 1.0 2.0 1.0 1.0 3.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 3.0 1.0 NA 1.0 2.0 3.0 2.0 2.82312802048385 0.5796392710816557 0.6505304049549516 GO:0042401 cellular biogenic amine biosynthetic process biological_process 21.026816227353443 23.295800407430633 22.914862120276197 23.07296728447149 NA 20.82219140117494 19.089141783922397 23.988834614079558 18.471922150979065 20.350967504713527 19.127564469999864 23.561478290748113 19.72629099252307 17.126816036389705 20.064675325974623 24.88577987542469 20.767601286350327 22.99627525821128 22.59405287388071 20.60879439973645 20.012434457263545 17.509220775954145 20.85919360311355 25.22161002476253 20.01475819749404 21.006363987005084 3.0 2.0 NA 4.0 2.0 5.0 3.0 1.0 2.0 5.0 3.0 2.0 4.0 7.0 2.0 5.0 16.0 5.0 2.0 1.0 2.0 5.0 2.0 2.0 2.0 2.0 NA 2.0 1.0 2.0 2.0 1.0 1.0 2.0 2.0 1.0 2.0 2.0 1.0 2.0 1.0 2.0 1.0 1.0 1.0 2.0 1.0 2.0 -2.26898418007719 0.05640180118754527 0.08910056693931202 GO:0042440 pigment metabolic process biological_process 24.125779702136274 25.461579697528208 24.66321245759215 25.41038402943182 24.172000750567474 26.040872780741363 23.610531691557068 25.10277990010993 23.22355026687304 25.561607005363488 24.161692550838122 25.15717356220076 25.146580142768702 25.505652905226587 23.595069794016705 25.718009777046234 23.50969218580737 24.905138337970147 23.345966856012968 25.74260402380581 23.77363594706812 25.36206040067735 24.189300319032288 25.66582459086669 24.683114266437308 24.89103608296875 18.0 28.0 15.0 22.0 22.0 41.0 29.0 50.0 23.0 41.0 52.0 37.0 20.0 38.0 27.0 35.0 35.0 58.0 26.0 31.0 41.0 29.0 46.0 45.0 2.0 2.0 3.0 1.0 3.0 2.0 3.0 3.0 2.0 2.0 3.0 3.0 2.0 2.0 2.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 3.0 2.0 -1.335799995391934 6.784570247173055e-05 0.0005498145239267514 GO:0042455 ribonucleoside biosynthetic process biological_process 25.41679093315009 26.66356369314268 25.90996926949193 26.71529776246043 25.97335409049808 26.713501361361853 24.706974343952023 26.669744780168834 24.5552301593968 26.33006098912921 25.07037976506793 26.317402558590214 25.96209773856786 26.796456351477474 25.052695181528648 26.692779408049393 24.847480272116872 26.390258883196946 25.201060493726352 27.077693978226232 25.92413110491387 26.452441109411197 25.53512907102916 26.942986034696627 25.25700404606632 26.647979934980768 51.0 63.0 62.0 81.0 44.0 88.0 53.0 84.0 54.0 82.0 69.0 65.0 57.0 84.0 43.0 88.0 76.0 76.0 75.0 78.0 59.0 83.0 50.0 90.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.2467727599925915 3.225641456243767e-05 0.0005099643033035255 GO:0042558 pteridine-containing compound metabolic process biological_process 27.69332615119486 25.81392124506177 25.490021916168732 25.573915631526226 25.335779459754338 24.681164523159147 26.58758694834596 25.58256046762536 26.79200485644084 25.56758042112737 27.48081660368276 26.135077892485977 26.56887591729792 26.37300311672482 28.993361774326573 25.63846094166965 26.70099869338684 25.03557311233764 29.91326201076388 26.80015718975304 25.51914054679961 25.022411963345075 27.29846006950289 25.99618598747401 27.09407326459145 25.974527539640164 59.0 59.0 41.0 79.0 82.0 115.0 82.0 99.0 101.0 93.0 94.0 78.0 120.0 99.0 61.0 77.0 115.0 132.0 90.0 41.0 91.0 110.0 109.0 102.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 1.8794049061330895 0.017926339076638688 0.03379466943753034 GO:0042559 pteridine-containing compound biosynthetic process biological_process 25.317855996762177 22.74132156227113 20.421167125471907 22.12372369286417 17.382100037946756 21.75753063829959 22.422455859850775 22.79668365546177 21.663938820319068 22.178606783796702 23.67146643555193 22.67583751001824 22.584006925706397 24.02252399470665 27.09959040344513 22.83770860912868 22.85287512573359 21.65932358421174 28.156454323769665 22.830843447802586 19.527310280732255 19.278995370038352 23.185960991892532 23.860269393804344 23.373077638305325 22.544239184115376 8.0 10.0 2.0 17.0 10.0 25.0 11.0 17.0 14.0 16.0 11.0 17.0 19.0 22.0 7.0 15.0 19.0 26.0 10.0 1.0 15.0 29.0 17.0 17.0 1.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 3.0 2.576534434491048 0.6861059569955559 0.7413508522341591 GO:0042578 phosphoric ester hydrolase activity molecular_function 25.92073107983746 25.218329094002012 24.05552518360676 23.880603970016786 23.74097101368381 25.98579920430117 25.52056257542869 25.125837617546807 24.62787317891944 24.327792724875394 25.775432693141784 25.21851974465493 26.43728880637985 23.93579290726471 26.153126593900623 26.15910995617239 25.412164670202014 24.266439503051465 26.440940640064937 24.74313599491265 26.91508582459645 25.820764026748233 26.50266873987939 23.977040887683028 26.187662754060092 26.156720516074714 40.0 28.0 21.0 29.0 48.0 40.0 46.0 39.0 59.0 55.0 64.0 31.0 69.0 51.0 45.0 41.0 68.0 38.0 72.0 35.0 61.0 30.0 66.0 65.0 3.0 3.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 1.0 3.0 3.0 3.0 5.0 2.0 3.0 3.0 2.0 3.0 3.0 0.7024019858354471 0.0832645166635504 0.12534875367444018 GO:0042592 homeostatic process biological_process 29.494149068009058 29.67740130132765 28.187336488516106 30.4421940864232 29.68287826380777 29.94097875856389 30.719432013029863 28.893439811722487 28.828968975134906 29.1837441787255 27.848126058299126 26.83563816472993 30.502312743001752 30.19277435443161 28.747916502111263 30.041927658421002 28.420212894892355 28.917918836341343 29.322542465376987 30.659227281556344 28.53536155325077 30.09905375045734 30.48016110818109 28.12565785423952 28.984331740133214 29.176952594557648 134.0 109.0 63.0 128.0 146.0 194.0 123.0 145.0 130.0 127.0 114.0 150.0 132.0 151.0 114.0 158.0 144.0 182.0 97.0 124.0 142.0 156.0 127.0 141.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 2.0 3.0 -0.18325223331859064 0.5253727863737021 0.6008633207515945 GO:0042623 ATPase activity, coupled molecular_function 28.706415677472428 29.750092726728745 28.495400161275573 29.186915339797764 28.09432276743159 29.458412981403537 28.38352096748094 29.70741386801184 28.535671496012892 29.593263304153794 28.866602566028853 29.823991214229864 28.81923766239829 29.661820986237398 28.487300644280506 30.116577517500925 28.56525435081079 29.893345078168988 29.261706175193247 29.79907974082603 29.090761667660512 29.49010754426697 28.717192751477928 30.149005684171428 28.77280227223052 29.838831888312807 377.0 470.0 305.0 546.0 350.0 585.0 425.0 559.0 446.0 612.0 481.0 580.0 471.0 645.0 346.0 558.0 486.0 645.0 389.0 547.0 400.0 621.0 441.0 658.0 5.0 4.0 4.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 -1.043677049256317 4.146041132679973e-05 0.0005099643033035255 GO:0042625 ATPase coupled ion transmembrane transporter activity molecular_function 28.52059422036081 29.494592141854024 28.315856535004052 28.882434497888397 27.96984011948916 29.23013316586944 28.1674163423414 29.44205143035548 28.3293982463372 29.414607143130517 28.62857272169681 29.5365304353756 28.613046345930506 29.22843002471797 28.23802263326277 29.8971323340697 28.36032786826713 29.705347043004828 29.05546779532669 29.564236923245677 29.00482994649289 29.347824992384854 28.56151909520582 29.735848196437825 28.595905427100305 29.668441019622183 250.0 248.0 225.0 300.0 245.0 321.0 320.0 366.0 291.0 353.0 308.0 272.0 322.0 338.0 243.0 312.0 312.0 390.0 309.0 338.0 292.0 292.0 306.0 423.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.9739979214932148 5.312128159411724e-05 0.0005099643033035255 GO:0042626 ATPase activity, coupled to transmembrane movement of substances molecular_function 28.646603664877897 29.66822269918919 28.40757537622088 29.076767671639104 28.06599558375387 29.351744670292447 28.297705307151226 29.619300175490853 28.492402702517772 29.55370722598785 28.819575103963214 29.75070980504813 28.74561449009251 29.52341141664505 28.439453083122405 30.05159578116306 28.478145110397215 29.840567798430254 29.178702261029247 29.726458281794706 29.072775738405195 29.44231711933211 28.672171371735267 30.01109812335441 28.700629301841122 29.78432193292218 320.0 380.0 284.0 437.0 302.0 503.0 399.0 503.0 386.0 523.0 410.0 465.0 432.0 559.0 318.0 478.0 396.0 551.0 365.0 488.0 365.0 522.0 387.0 563.0 13.0 11.0 11.0 12.0 8.0 14.0 8.0 12.0 12.0 14.0 12.0 12.0 16.0 13.0 11.0 17.0 11.0 13.0 13.0 14.0 11.0 14.0 14.0 14.0 -1.0216190343112928 4.146041132679973e-05 0.0005099643033035255 GO:0042723 thiamine-containing compound metabolic process biological_process 20.000676648003765 23.015766854672783 18.90148763795205 23.33391858748233 17.389452525881946 22.580335138537663 19.61445642242781 23.222966505011268 20.134685954222068 22.695860630982718 20.661894798079114 23.04439207665596 15.94086806350475 23.02556639934807 NA 23.61997263298181 15.075947234298216 22.598423533799334 21.54362745592932 22.77077367345507 16.491946765369867 22.072140833200493 20.51638005868707 24.070931210070423 21.26451771599684 21.375196920842377 4.0 20.0 2.0 20.0 8.0 22.0 8.0 12.0 10.0 22.0 1.0 25.0 NA 32.0 2.0 18.0 16.0 20.0 2.0 8.0 8.0 37.0 11.0 10.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -3.0150902066690186 6.321587792507137e-05 0.0005498145239267514 GO:0042726 flavin-containing compound metabolic process biological_process 23.232147565835856 22.63001143645869 21.204767478498407 22.43409844939692 NA 22.342359176005544 22.781290977157912 20.58473126284437 24.12412297641377 19.77005010634582 24.15917794680087 23.088716532497955 23.025441220809626 23.562623998932864 23.205107433179602 22.552894938484343 22.623126780021487 20.06402992759857 21.91259573450368 23.06076491071093 NA NA 23.339920732626748 24.14171511391817 23.593026842419032 21.023817993362318 5.0 32.0 NA 10.0 10.0 17.0 37.0 9.0 19.0 29.0 14.0 47.0 22.0 44.0 17.0 9.0 10.0 25.0 NA NA 20.0 41.0 34.0 12.0 3.0 4.0 NA 3.0 2.0 4.0 4.0 4.0 4.0 4.0 2.0 4.0 4.0 4.0 4.0 4.0 2.0 4.0 NA NA 2.0 4.0 4.0 4.0 0.6021361293771648 0.10531581841575224 0.15148805703407617 GO:0042727 flavin-containing compound biosynthetic process biological_process 22.201250731492923 21.352602524698575 19.88283938361104 21.12085031235934 NA 21.020431081118183 21.781290977157912 19.31308227309088 23.08817270678428 18.638501069927766 23.119426994368574 21.78541303659164 22.025441220809626 22.24758880887812 22.16674882589965 21.259223705853763 21.603145992811832 18.895967981554687 20.91259573450368 21.917015327978216 NA NA 22.339920732626748 22.839063306360412 22.55810671170813 19.83256757968821 2.0 13.0 NA 4.0 5.0 7.0 17.0 4.0 9.0 12.0 7.0 19.0 10.0 18.0 8.0 4.0 5.0 11.0 NA NA 10.0 17.0 16.0 5.0 2.0 3.0 NA 2.0 1.0 3.0 3.0 3.0 3.0 3.0 1.0 3.0 3.0 3.0 3.0 3.0 1.0 3.0 NA NA 1.0 3.0 3.0 3.0 0.8486482067943477 0.05726498942466171 0.08978229497735907 GO:0042737 drug catabolic process biological_process 25.942749789137693 23.14875138506473 23.171730096342177 19.72277675296461 25.300458666586927 24.761375204305672 25.88020246696067 23.326165810793558 25.942839124835 19.966185119045104 26.401462281089373 21.096948854989115 26.09087145341456 23.340329070342932 26.010705605870058 22.550763290228247 25.859122882760033 22.266894210684704 27.250228387374854 25.01800160271049 24.750332518051053 22.472634283871574 25.68440137831156 20.46249378398168 25.988357816025506 22.37946675672556 15.0 5.0 52.0 40.0 32.0 17.0 20.0 4.0 28.0 11.0 34.0 16.0 27.0 13.0 24.0 9.0 96.0 30.0 52.0 11.0 35.0 7.0 23.0 18.0 4.0 3.0 5.0 4.0 7.0 3.0 4.0 2.0 5.0 5.0 6.0 5.0 7.0 3.0 6.0 3.0 7.0 7.0 6.0 4.0 4.0 4.0 3.0 5.0 2.793998404072962 0.0001386794054294884 0.0007006959432226783 GO:0042777 plasma membrane ATP synthesis coupled proton transport biological_process 24.39602893752036 25.25836062341477 23.908047639665853 25.030935271638945 24.614894358253466 25.14559496246525 23.667985993963388 25.090627030794113 24.68226455896173 24.99064020125668 24.012415961818327 25.11845591445129 24.970873097913213 25.49332552948871 24.33011544160529 25.526482482273146 23.458206573012642 25.274395011419358 24.63671306653959 25.62315363363632 24.27679671236033 24.662199529029245 24.96975424978054 25.47375798481443 24.360979953924822 25.38275851932013 24.0 43.0 49.0 49.0 29.0 46.0 48.0 39.0 29.0 27.0 42.0 41.0 42.0 55.0 21.0 37.0 31.0 48.0 25.0 41.0 34.0 30.0 35.0 39.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8623316858944108 6.784570247173055e-05 0.0005498145239267514 GO:0042816 vitamin B6 metabolic process biological_process 23.17414575397252 21.937643941286634 20.006307529898237 18.82753091839228 21.77025293245425 22.79379552796821 22.36075991492734 20.314828188412708 24.44993533666429 18.18588019631241 24.06923711466238 21.430799773828486 23.36900019463204 17.901430341063065 22.14273784745593 23.669428108757806 22.516589638100136 23.636936844198928 22.860384990479712 16.3077564537699 22.86077541722507 20.812397036392483 23.106990938576 22.550541203340263 24.045297239834515 20.353789988629085 2.0 4.0 6.0 14.0 14.0 4.0 6.0 2.0 18.0 10.0 20.0 2.0 8.0 26.0 12.0 20.0 30.0 2.0 18.0 6.0 20.0 24.0 20.0 6.0 2.0 3.0 2.0 3.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 1.236501812685887 0.02092133533779403 0.038284203081476474 GO:0042819 vitamin B6 biosynthetic process biological_process 22.17414575397252 20.93764394128664 19.006307529898237 17.82753091839228 20.770252932454255 21.793795527968207 21.36075991492734 19.314828188412708 23.44993533666429 17.18588019631241 23.06923711466238 20.430799773828486 22.36900019463204 16.901430341063065 21.14273784745593 22.669428108757806 21.516589638100136 22.636936844198928 21.860384990479712 15.307756453769901 21.860775417225064 19.812397036392483 22.106990938576 21.550541203340263 23.045297239834515 19.353789988629085 1.0 2.0 3.0 7.0 7.0 2.0 3.0 1.0 9.0 5.0 10.0 1.0 4.0 13.0 6.0 10.0 15.0 1.0 9.0 3.0 10.0 12.0 10.0 3.0 1.0 2.0 1.0 2.0 2.0 1.0 1.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 1.23650181268588 0.02092133533779403 0.038284203081476474 GO:0043021 ribonucleoprotein complex binding molecular_function 22.62864461221221 23.283163538971305 23.166113959501573 23.45263697505505 23.15962333723272 22.992090430067748 22.038035229104647 23.64857172851304 22.899055921288877 22.70328476701827 22.443920677748853 23.94082882318337 22.420686529016752 23.1836778764435 21.772608402992415 22.896225181837373 21.074002466849343 23.6850520356218 23.223596466495003 23.142995043958287 22.584301495990072 23.509429930490732 22.902833641449643 22.5811223942508 22.485470310098314 22.98270264755399 12.0 5.0 11.0 9.0 7.0 7.0 9.0 6.0 11.0 8.0 11.0 6.0 8.0 7.0 7.0 8.0 10.0 12.0 7.0 5.0 10.0 7.0 9.0 9.0 2.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 1.0 2.0 2.0 2.0 1.0 1.0 2.0 2.0 1.0 2.0 -0.6545189267590956 0.007911788680711459 0.016907384030013527 GO:0043022 ribosome binding molecular_function 22.602788477967643 23.25420525129673 23.14503254423136 23.45263697505505 23.15962333723272 22.992090430067748 22.038035229104647 23.64857172851304 22.899055921288877 22.70328476701827 22.384308991734404 23.92017165246468 22.381017476269236 23.157696019640586 21.772608402992415 22.896225181837373 21.074002466849343 23.645852122855658 23.16037407893043 23.06876947823723 22.584301495990072 23.509429930490732 22.8190374749985 22.471101450231632 22.485470310098314 22.84616106869592 11.0 5.0 11.0 9.0 7.0 7.0 9.0 6.0 10.0 7.0 10.0 5.0 8.0 7.0 7.0 7.0 9.0 11.0 7.0 5.0 9.0 6.0 9.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.651416773329089 0.011074437676156606 0.022291771322328135 GO:0043043 peptide biosynthetic process biological_process 30.88600586391985 30.21719695613554 29.953437152825185 29.528401607002287 29.561546984402003 30.207902629115342 30.379518854985523 30.239173150059514 31.06043612562377 29.823085381208987 31.04439735365448 30.459083779713946 31.011059690271093 30.17806337552751 31.295157801799466 30.46133594095111 30.49490475535583 29.964974555185922 31.62569866321196 30.588613812926244 30.68054577006255 30.016233485147172 31.471545655193683 30.489018357209826 30.74930642363418 30.29997364657299 477.0 224.0 269.0 487.0 488.0 382.0 716.0 386.0 640.0 473.0 578.0 280.0 856.0 372.0 523.0 342.0 754.0 658.0 552.0 257.0 690.0 337.0 521.0 436.0 2.0 3.0 3.0 3.0 2.0 2.0 2.0 2.0 1.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 2.0 0.6688089077843102 0.007911788680711459 0.016907384030013527 GO:0043093 FtsZ-dependent cytokinesis biological_process 25.975873741817388 27.15233275333737 26.650247340103444 27.026760844902157 26.42233569469473 26.374014252424487 24.78912869244929 27.164906185728746 24.370416844260816 27.184003482820692 24.73292574880167 27.383010502618397 25.57450035501203 27.08727276947832 26.684494404448827 27.46184255671895 25.498009473802306 26.92716870830073 26.543235548411108 27.62163411373985 26.521403305776715 26.884128644295558 26.106697301008342 27.317479875594 25.472111743097358 27.01502958048017 53.0 46.0 47.0 48.0 37.0 70.0 22.0 66.0 38.0 53.0 38.0 45.0 68.0 78.0 33.0 65.0 73.0 72.0 52.0 65.0 43.0 71.0 47.0 64.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.176459011519981 0.00010962068302139599 0.000648372570666835 GO:0043094 cellular metabolic compound salvage biological_process 27.856650790171965 28.56977056007989 27.997232827083998 28.228878641005693 27.20573603805079 28.33143684054697 28.13595580176261 28.65535741017468 27.405290437576127 28.75835444300877 28.28850239554173 28.636791445044928 28.39440758893955 28.456350385966033 27.13371287263114 28.605592126113912 27.45409674868916 28.414067223926736 28.24528237094859 28.609019879072147 28.18731648694392 28.3399073313767 27.364620872212072 29.129183644079127 27.66398060776724 28.438796430718952 203.0 213.0 148.0 197.0 217.0 236.0 211.0 259.0 228.0 287.0 247.0 194.0 221.0 253.0 209.0 269.0 297.0 317.0 200.0 202.0 221.0 271.0 232.0 280.0 4.0 5.0 5.0 5.0 6.0 5.0 6.0 5.0 5.0 5.0 6.0 5.0 5.0 4.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 6.0 5.0 -0.713119769907923 0.00010962068302139599 0.000648372570666835 GO:0043101 purine-containing compound salvage biological_process 26.035077777187986 26.949262243683272 26.396649400102852 26.891291439324498 25.453510921086753 26.946517135724235 26.65823884948785 27.033869614721798 25.576897943784914 27.08722927835876 26.423376872213716 26.748282835238715 26.849934608110857 26.84306769433164 25.46081134442964 27.10584345887949 25.53877945284464 26.829989195935802 26.25977084942976 27.0284579324972 25.620787244796638 26.70943108560289 25.43894582791998 27.40387528160099 25.619695822498326 26.576974334469856 60.0 73.0 40.0 56.0 59.0 78.0 53.0 82.0 66.0 79.0 68.0 64.0 61.0 85.0 53.0 82.0 80.0 95.0 51.0 66.0 48.0 73.0 55.0 85.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.9141844664952856 0.0001386794054294884 0.0007006959432226783 GO:0043167 ion binding molecular_function 32.280976426791575 32.138253184061625 31.541252011324378 31.371217453171983 31.481688137182413 31.96535040078357 32.13025791106916 32.236655812711895 32.50790774101421 32.187469957297566 32.60837463848384 32.27590257950197 32.481774212521344 31.961050839764308 32.57916615761799 32.23584273381236 32.057450456367505 32.13195304631754 32.599378786634134 32.345480378896454 32.15518106981883 32.017175503229105 32.346355542005426 32.22744402868274 32.358778855558164 32.439412649238484 2112.0 2039.0 1948.0 2543.0 2886.0 3298.0 3317.0 3222.0 3498.0 3289.0 3505.0 2595.0 3629.0 3260.0 2635.0 3320.0 4338.0 3952.0 2654.0 2673.0 3296.0 3145.0 3380.0 3347.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.14272324272995007 0.14891467317876572 0.20512749682902828 GO:0043168 anion binding molecular_function 31.45752760074565 31.144684512165888 30.56351373855652 30.38832319293429 30.3927236389936 31.146748773625642 31.26391489280993 31.28023855478707 31.72525800985728 31.14933059475273 31.84076867153361 31.271066936438746 31.62274192360292 30.912336056369792 31.63595126828161 31.17474528733889 31.216909036024 31.07716188520753 31.936929592346072 31.379606255780306 31.480225089278914 31.159062443347413 31.51020691046586 31.167136385772015 31.534331943065794 31.38855562658357 939.0 955.0 826.0 1201.0 1447.0 1577.0 1720.0 1460.0 1770.0 1492.0 1691.0 1240.0 1821.0 1492.0 1334.0 1498.0 2159.0 1903.0 1188.0 1197.0 1611.0 1454.0 1645.0 1517.0 8.0 7.0 7.0 6.0 8.0 7.0 9.0 7.0 10.0 9.0 11.0 8.0 9.0 8.0 11.0 10.0 7.0 7.0 8.0 7.0 10.0 8.0 9.0 9.0 0.3128430885797613 0.01531382171343201 0.02967647437634029 GO:0043169 cation binding molecular_function 31.079767019694195 31.131793057589828 30.518641380248066 30.353906458050837 30.565483792633124 30.757818488844446 30.98294226170988 31.19171534616589 31.25190287398579 31.22462697409087 31.331220457112646 31.280722068527236 31.325525784809585 31.00817428248109 31.5200540559528 31.29445751627856 30.878151588219104 31.18473924320161 31.157921505778532 31.310527682522515 30.73493536108829 30.859796750884318 31.161482036490106 31.285331516380573 31.15886525495731 31.48853776931455 1173.0 1084.0 1122.0 1342.0 1439.0 1721.0 1597.0 1762.0 1728.0 1797.0 1814.0 1355.0 1808.0 1768.0 1301.0 1822.0 2179.0 2049.0 1466.0 1476.0 1685.0 1691.0 1735.0 1830.0 3.0 3.0 3.0 1.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.05202603789563298 0.5637028616507731 0.6360770084449954 GO:0043170 macromolecule metabolic process biological_process 33.314355889999966 33.04888852214292 32.663689368598234 32.470755719909924 32.282200491726314 32.989018305867326 32.86284296653979 33.12880177258115 33.41458321122458 32.769728672164284 33.498125618951306 33.247104905410964 33.49413444182171 33.06729112023255 33.6134013705814 33.285906884027554 32.89857413852706 32.83234764237723 33.96962210088893 33.36410576332202 33.18013028270544 32.78504373230398 33.78007803760691 33.3284171613845 33.24829406659307 33.04836069696028 4855.0 4552.0 3732.0 5921.0 5384.0 6446.0 6548.0 5868.0 7145.0 6713.0 6956.0 5607.0 7464.0 6653.0 5116.0 6166.0 8687.0 7810.0 5420.0 4666.0 6480.0 6353.0 6517.0 6277.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 9.0 0.26546736785704894 0.13332693177434943 0.18549833985996442 GO:0043171 peptide catabolic process biological_process 23.814209669540528 22.96920036822538 23.019603195265926 23.25955849081982 23.437238014735843 23.42988819795825 24.157253012076996 22.244763602270307 24.03972048434381 22.190660162517663 24.14399278951488 23.665126942973863 23.98008492990084 23.737122583115525 23.807457954293838 22.005733637764575 24.31068962820275 21.979240897778002 22.812007407994326 23.641553658636077 21.74089279342388 22.66792597069031 22.77435447566413 22.663675805371252 24.956839614926967 22.368119851440223 13.0 16.0 17.0 16.0 22.0 14.0 19.0 16.0 20.0 14.0 22.0 18.0 16.0 15.0 18.0 13.0 16.0 28.0 14.0 16.0 18.0 13.0 31.0 18.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.8450093013151481 0.01531382171343201 0.02967647437634029 GO:0043173 nucleotide salvage biological_process 26.58191166759332 27.09280485795989 26.56395807846893 26.652841961330573 25.86078048521333 26.688532564991952 26.99609018018021 27.2060503615559 26.11955044198433 27.30237408204762 27.052497375762762 27.229865753462192 27.09241169955489 26.867231790723253 25.776641489711647 27.173647122363356 26.227947701873685 27.0224328536728 27.037855443296234 27.158465524054225 26.87312001955625 26.81058636713961 26.075688533987645 27.619936897283324 26.402558559764838 27.084602470552092 82.0 77.0 62.0 76.0 83.0 87.0 81.0 93.0 90.0 108.0 99.0 73.0 87.0 98.0 82.0 101.0 113.0 121.0 79.0 78.0 91.0 107.0 94.0 108.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.5108931903665699 0.005583616806378765 0.012692811975156102 GO:0043190 ATP-binding cassette (ABC) transporter complex cellular_component 26.00363610471213 26.285176968076787 26.761778839636268 26.66738353801051 27.487588275645646 25.894038261084532 24.620311076539537 26.22688518264325 25.20128783187475 25.794887301515928 25.09769942200169 25.91350659564753 24.99736142234126 26.69963816889141 26.80000773654563 26.962495874405175 25.395663434592446 25.373987830414052 25.698723983190234 26.413926786970247 26.108944595691337 26.21811285972559 25.041885878914215 26.579565794916004 25.55313325135705 25.871997479061307 57.0 63.0 72.0 65.0 38.0 92.0 65.0 70.0 61.0 70.0 62.0 70.0 59.0 75.0 48.0 56.0 57.0 81.0 58.0 71.0 61.0 74.0 81.0 76.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.28154086336465767 0.0832645166635504 0.12534875367444018 GO:0043207 response to external biotic stimulus biological_process 21.72323670778597 20.82242733926768 17.5973256134569 20.990058156891124 NA NA 20.2985105503726 NA 23.840516628055482 NA 16.288235946851096 20.92493427020617 22.400875231560192 21.773424549769867 20.768345707611736 18.91530920884669 NA 18.90519727516316 NA 19.35997531919379 18.296092461171643 NA NA 21.804775758868352 NA NA 4.0 4.0 NA NA 6.0 NA 57.0 NA 2.0 6.0 20.0 8.0 10.0 4.0 NA 2.0 NA 4.0 4.0 NA NA 10.0 NA NA 1.0 1.0 NA NA 1.0 NA 1.0 NA 1.0 1.0 1.0 1.0 1.0 1.0 NA 1.0 NA 1.0 1.0 NA NA 1.0 NA NA 0.9008093685182885 0.5652987983097892 0.636726444305611 GO:0043225 ATPase-coupled anion transmembrane transporter activity molecular_function 19.94072178652973 22.2649534613484 20.88413641618008 22.09946838986245 21.20955562658629 22.92760386824153 NA 22.57721306739263 17.82995249704157 21.15811976244468 NA 21.35279993902799 18.78894948208356 22.553238548547114 19.624391102169106 22.130810449268512 18.440005305929784 21.673198831454048 20.97211542400382 22.70810249778864 18.10547239159748 21.964349934947414 NA 23.11649447355072 18.954889440547728 21.31091714065968 9.0 14.0 7.0 16.0 NA 14.0 2.0 7.0 NA 13.0 4.0 24.0 3.0 17.0 3.0 13.0 11.0 14.0 3.0 7.0 NA 15.0 3.0 7.0 2.0 2.0 1.0 2.0 NA 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 1.0 2.0 3.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 -2.324231674818673 0.00016552160560065154 0.0008236168584623857 GO:0043226 organelle cellular_component 31.273883151695138 31.120695122546223 30.73517576206881 30.55375604985307 30.024036714388608 30.79782963925716 31.07001192788414 31.28315988455163 31.653279695878464 31.226709835529427 31.56792841425202 31.440350952812786 31.475846940061608 31.05257273358855 31.57350634359008 31.2392669880574 30.978727217719733 30.91471011122199 31.32252340502129 31.317009853584317 31.120404294199467 30.801658873927394 31.79871386863468 31.401490269732324 31.165810186694387 31.13971169530023 646.0 428.0 484.0 732.0 822.0 751.0 934.0 676.0 940.0 760.0 924.0 526.0 1145.0 674.0 748.0 630.0 942.0 884.0 895.0 566.0 967.0 616.0 896.0 769.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 3.0 5.0 4.0 4.0 3.0 0.1531880291489145 0.27265646879500405 0.34545713000625894 GO:0043227 membrane-bounded organelle cellular_component 26.009484775236157 25.798797177380123 25.51933558784175 23.376532314932604 24.100016798201466 24.29794251637701 26.202699192329426 26.082692787472023 26.034451766766853 26.79318027983823 26.506324398115392 26.498343458959603 26.43239887698623 25.253060043076296 25.58192392841444 24.954045574275032 26.090081415064635 26.035126859554964 25.86154223537046 25.9288032598212 25.644088519287443 25.53577385652483 26.72908045043942 25.049766485676297 25.98453617708725 26.550613434250213 25.0 12.0 18.0 10.0 22.0 25.0 28.0 21.0 38.0 32.0 28.0 25.0 27.0 22.0 28.0 29.0 24.0 30.0 27.0 17.0 28.0 25.0 25.0 17.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 0.2106875978560332 0.4189234409463829 0.5022252202700153 GO:0043229 intracellular organelle cellular_component 30.27224666811883 30.119667637218953 29.734235350090863 29.55224199170206 29.02256501218103 29.79478695445361 30.07001192788413 30.282004212869293 30.65273903479933 30.226709835529427 30.561893314013858 30.439501413012604 30.474299564820036 30.05089498421765 30.57266802793621 30.237401826916948 29.975783393785928 29.913981424271363 30.32195427795741 30.316147834744054 30.119362766288127 29.801658873927394 30.796386765074026 30.40047407650437 30.16559830918797 30.13966734030476 321.0 211.0 240.0 363.0 411.0 372.0 464.0 338.0 464.0 376.0 459.0 261.0 570.0 332.0 369.0 312.0 469.0 440.0 446.0 283.0 480.0 306.0 447.0 384.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.1525790308998758 0.27265646879500405 0.34545713000625894 GO:0043231 intracellular membrane-bounded organelle cellular_component 25.979263272652712 25.77805351229931 25.501759844974107 23.262645557456516 24.05465546475017 24.146806748445968 26.202699192329426 26.062118993652355 26.021108681235727 26.79318027983823 26.402083928747373 26.48523080735487 26.40666952715967 25.20559248866775 25.55679316428905 24.878664002491035 26.04585232747209 26.024364160705854 25.84895571148375 25.91064395535862 25.636827727499213 25.53577385652483 26.692388743574448 25.007677116150646 25.980687415341443 26.550613434250213 23.0 9.0 16.0 6.0 22.0 22.0 25.0 21.0 32.0 28.0 25.0 23.0 25.0 16.0 23.0 26.0 22.0 28.0 26.0 17.0 25.0 23.0 24.0 17.0 4.0 3.0 3.0 3.0 4.0 4.0 3.0 4.0 5.0 4.0 5.0 4.0 4.0 5.0 4.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 0.20120976035340377 0.4884223166225936 0.5675521891480417 GO:0043232 intracellular non-membrane-bounded organelle cellular_component 30.19670647550893 30.046684681883654 29.65536952127648 29.53368070373745 28.97571416798307 29.76559023412575 29.967607279722706 30.20242769789353 30.593333680624024 30.086590343223854 30.478833903002105 30.343291221424057 30.385588073892087 29.999814040415245 30.52737353370009 30.20178752430432 29.87787947302576 29.8132039912943 30.255482955808834 30.246414676442946 30.0533395584714 29.72464747729217 30.70995110705187 30.365720352391108 30.084012843082967 30.01450782944685 298.0 202.0 224.0 356.0 389.0 350.0 439.0 317.0 432.0 348.0 434.0 238.0 545.0 315.0 346.0 286.0 447.0 412.0 420.0 266.0 455.0 283.0 423.0 367.0 3.0 3.0 3.0 4.0 4.0 3.0 4.0 4.0 5.0 4.0 4.0 3.0 4.0 4.0 3.0 5.0 3.0 5.0 4.0 4.0 4.0 5.0 3.0 4.0 0.15002179362527457 0.27265646879500405 0.34545713000625894 GO:0043244 regulation of protein complex disassembly biological_process 23.907570983090128 25.775009890521282 25.07376539230899 25.55353588295669 24.155682818544715 25.29504289290545 22.847054553922444 25.974377668230638 22.52215620719801 25.75479430261665 23.255850024843287 25.987340602782844 23.680102163498248 25.90085235739175 23.876928638701084 25.761674607605638 23.28588858593915 25.606365433638054 25.10336056530962 26.01326087703185 23.805383700970268 25.19147259845641 22.736801385765553 26.39088003374669 23.787063438547438 25.41930352092808 39.0 44.0 31.0 41.0 20.0 62.0 20.0 62.0 28.0 59.0 29.0 52.0 32.0 62.0 28.0 67.0 55.0 67.0 32.0 46.0 22.0 60.0 36.0 66.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.8674389074311541 3.225641456243767e-05 0.0005099643033035255 GO:0043335 protein unfolding biological_process 22.673704705526102 20.97235950179687 20.57238599479164 NA 21.72712703139399 21.35751917957705 22.064110963598953 NA 18.01156214991807 NA 22.794509313184072 21.12072279280924 23.26206081131576 NA 20.94144962925269 NA 21.98936856928381 NA 24.455518719965344 21.03489180501085 23.468208913683853 NA 22.972620798031173 19.869664964047228 22.020315754175645 21.077690426480828 7.0 NA 9.0 9.0 7.0 NA 2.0 NA 8.0 6.0 8.0 NA 4.0 NA 8.0 NA 25.0 8.0 12.0 NA 15.0 5.0 8.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.7013452037292325 0.07313979965890892 0.11239394291690516 GO:0043412 macromolecule modification biological_process 25.8059994906141 26.53677744094212 26.210945667361607 26.29672531220605 26.02403225576277 27.0417192411793 25.62558039423985 26.579218907191855 24.385749319497556 26.019054626528806 26.612658289548047 26.174649002208827 25.441342704439602 26.62242884242719 25.35713004404651 27.012996439807825 25.364327674205608 26.250230550007185 25.474333471773015 26.585528865965482 25.494007739602186 26.21093430801985 26.244088536626897 27.026650883430623 26.19232157976264 26.061301903418226 119.0 182.0 111.0 227.0 121.0 246.0 67.0 175.0 161.0 199.0 169.0 202.0 99.0 284.0 71.0 221.0 153.0 183.0 96.0 169.0 83.0 223.0 174.0 171.0 4.0 4.0 4.0 4.0 5.0 4.0 5.0 4.0 4.0 4.0 5.0 4.0 4.0 4.0 5.0 4.0 4.0 4.0 3.0 4.0 5.0 4.0 5.0 4.0 -0.7307779503280223 0.00268017172806849 0.006910856026093958 GO:0043414 macromolecule methylation biological_process 23.539851090524955 23.190292944255177 23.949638419893216 22.36824387466189 22.700607371225427 23.70577066333175 23.576218130241973 23.360755987285728 20.480676522947512 21.901198957383556 24.748287349537677 23.412919535604377 22.481653677127863 23.236281647563356 23.352970561731485 24.31614117209129 23.5485684404826 22.802406372150987 22.81282886412227 22.837317335386725 22.562655379283857 22.87746159909339 24.207741521182946 23.25806500177498 24.209366842008173 22.65150586697403 17.0 24.0 16.0 39.0 21.0 37.0 7.0 19.0 26.0 29.0 25.0 31.0 16.0 52.0 13.0 32.0 17.0 20.0 13.0 18.0 10.0 35.0 34.0 20.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 2.0 2.0 2.0 2.0 3.0 3.0 1.0 2.0 3.0 2.0 2.0 2.0 0.34955814626977855 0.4884223166225936 0.5675521891480417 GO:0043436 oxoacid metabolic process biological_process 32.98131937389929 32.966470713614626 32.55481956047677 32.14324441595129 32.31441202931209 32.770261452663824 32.69482182094641 32.922630503232035 32.844702794523236 32.76816533997035 33.251828486324264 33.20988432316415 33.15007193657144 32.60803948523282 33.34238928199674 33.29754456040199 32.48923364230363 33.39885165321484 33.57213085938292 33.25044362527201 32.58627919783173 32.714746128111685 33.271144229001216 33.21412451756406 33.09474242143672 32.821533590868896 3244.0 3577.0 3837.0 4826.0 3878.0 5954.0 4472.0 5820.0 5218.0 6083.0 5502.0 4573.0 5375.0 6046.0 3746.0 6525.0 6486.0 6316.0 4803.0 4952.0 5318.0 5787.0 4815.0 5881.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 0.01484866028466314 0.8624902301359216 0.8917877441670506 GO:0043531 ADP binding molecular_function 20.239873963815086 20.18307550610529 19.458706834024028 18.89132884521202 21.72893830886637 NA 18.897137789785273 20.611763630316922 20.821473355244194 20.405580368252174 17.35532907664442 21.424552097125886 21.28373771252554 20.03161797205184 19.3546900257627 18.637791734625203 19.9218732755646 19.212137195289415 20.00875432183133 19.32006123673984 20.022122434624354 20.33184783124252 20.46089873150528 18.654770455337665 18.512785531844248 21.151068535020162 3.0 1.0 4.0 NA 3.0 6.0 2.0 7.0 2.0 4.0 6.0 3.0 4.0 2.0 4.0 3.0 5.0 4.0 5.0 6.0 5.0 2.0 3.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.05679845770979597 1.0 1.0 GO:0043546 molybdopterin cofactor binding molecular_function 24.769884630095355 22.28000186771005 21.953617555799788 NA 18.576833812542503 16.496506535378746 25.199357351632177 21.299430680634586 23.01908273749553 23.416725845788328 25.46959418467573 23.755773673089532 25.5120794003734 20.188678399622127 23.33605270087252 18.97128037405427 24.013976931769882 22.237806490987182 25.35781372628841 21.8041702696374 26.249932207353147 20.210948901492323 24.87310809130733 22.20055184819265 23.970068677603393 23.471806496123254 18.0 NA 3.0 1.0 22.0 11.0 18.0 25.0 18.0 19.0 25.0 6.0 24.0 4.0 17.0 15.0 44.0 11.0 27.0 8.0 30.0 10.0 15.0 23.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 2.489882762385303 0.005613231495104934 0.012720084333021204 GO:0043588 skin development biological_process 20.817074602187176 20.41845399841354 20.387314549386023 19.235849842127674 21.261364997695946 20.954907391604237 18.69596105486389 19.52052979954168 14.85680639687384 13.42742056920834 21.761815949624186 20.474996322972764 21.1011235775836 20.734104904870307 21.767625646262196 21.283539527803907 20.39404333810246 20.30111248421413 19.723918511513787 18.14854154719847 14.054816149077675 NA 21.85076721660984 22.055803415476113 21.201032895763817 18.22327739211902 3.0 4.0 8.0 3.0 1.0 3.0 2.0 1.0 2.0 3.0 3.0 4.0 2.0 4.0 3.0 5.0 5.0 3.0 1.0 NA 3.0 4.0 7.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.3986206037736366 0.42365593666732415 0.5069248408061559 GO:0043590 bacterial nucleoid cellular_component 24.05756396173936 22.572224636528684 20.63890483652489 20.849453647663747 14.637279134082453 20.76630443830863 24.522109913652645 22.897468952366772 24.701483457326933 19.127541670435697 24.025243841326052 23.083054389306703 24.0090189947966 22.16598664120522 25.28259427673913 23.15166823755847 23.633676237700573 23.93997427299063 24.48363941977695 23.571339132351646 21.41941552384413 22.070305215033606 23.95613939129295 22.17600946605616 24.64106335300097 21.045726610633 2.0 5.0 1.0 3.0 5.0 7.0 7.0 5.0 8.0 10.0 3.0 4.0 7.0 5.0 6.0 5.0 10.0 9.0 8.0 7.0 4.0 3.0 6.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.4853393252106741 0.02092133533779403 0.038284203081476474 GO:0043603 cellular amide metabolic process biological_process 32.17956570012523 31.410688720753768 31.118394446910692 30.686486848253203 30.750241195697583 31.33522980797083 31.704524832240967 31.452048723001795 32.371246384435786 31.11818944150217 32.39644139010958 31.618445665397374 32.2919748341551 31.33680797231947 32.643535063169644 31.62939574554739 31.76615032177536 31.21548272180717 32.95823979285628 31.8009882104968 31.865078248478678 31.208607908743076 32.69642107749108 31.67424903620988 32.126623123785144 31.518444625963163 1196.0 644.0 744.0 1246.0 1391.0 1142.0 1898.0 1070.0 1727.0 1280.0 1591.0 794.0 2228.0 1097.0 1378.0 1013.0 2045.0 1817.0 1438.0 773.0 1790.0 1027.0 1523.0 1188.0 6.0 6.0 9.0 10.0 9.0 6.0 9.0 9.0 8.0 10.0 9.0 8.0 11.0 9.0 11.0 8.0 8.0 7.0 9.0 10.0 9.0 9.0 9.0 10.0 0.7688769793714627 0.004669131805023211 0.010994483948432015 GO:0043604 amide biosynthetic process biological_process 31.018054555211602 30.28520955959453 30.005277896181155 29.567790510091466 29.606222394373013 30.251322431617346 30.52039900123487 30.310013223702803 31.20627213229311 29.920067494854532 31.210568385378323 30.51329514498257 31.13746748003696 30.23012472824828 31.47702410623216 30.538621761197014 30.598738813415927 30.07519117351733 31.804033459202728 30.64821249079189 30.748191784575358 30.080341270863908 31.55254705748321 30.56594792186741 30.909450046848 30.372530671926523 525.0 263.0 308.0 536.0 581.0 472.0 820.0 446.0 738.0 544.0 670.0 330.0 957.0 456.0 588.0 419.0 886.0 768.0 617.0 309.0 780.0 426.0 628.0 505.0 4.0 4.0 5.0 4.0 7.0 4.0 6.0 5.0 6.0 5.0 7.0 5.0 7.0 4.0 7.0 4.0 6.0 5.0 5.0 4.0 6.0 6.0 7.0 5.0 0.7328449956170715 0.006656727227605034 0.01478219854101616 GO:0043648 dicarboxylic acid metabolic process biological_process 28.957831304594265 27.960090980933114 27.455984875372586 27.33788695445965 27.925126051127855 27.39007880332232 28.459436586667408 27.979395998025915 28.558172535126825 27.721524355549725 29.09926891303611 28.340123579892932 29.08488920952348 28.04567819539789 29.110159294165893 27.868483628813127 28.078752153143178 28.269618677791843 30.294860779326005 28.57972070807063 28.66577441816395 27.255318582422234 29.52312408665863 27.96162511663493 28.98541007787628 28.1291177374908 170.0 250.0 241.0 260.0 171.0 353.0 196.0 330.0 243.0 368.0 309.0 322.0 257.0 330.0 181.0 350.0 367.0 392.0 270.0 256.0 260.0 323.0 253.0 326.0 8.0 10.0 7.0 6.0 9.0 7.0 10.0 8.0 11.0 9.0 13.0 11.0 9.0 6.0 10.0 7.0 12.0 12.0 9.0 5.0 11.0 7.0 10.0 8.0 0.9977403236611515 0.003892417122778628 0.009377869824763952 GO:0043650 dicarboxylic acid biosynthetic process biological_process 25.42798969885077 25.833823422307137 24.043348393644614 25.041780366570464 25.655524787416873 25.4639795782729 24.07048378138023 26.077739025369787 22.319436935136228 26.00347856654561 25.227386701401592 25.960834584527106 25.115532570939074 26.052001250826805 26.290754027641945 25.656704041424323 24.82827029204067 26.586045097366423 27.391068310824352 25.54899428506 24.603269214303907 24.74479708335781 25.15015589310784 25.91780010522204 24.421563110614024 26.053681262537754 41.0 68.0 56.0 66.0 28.0 105.0 23.0 94.0 35.0 103.0 61.0 98.0 42.0 95.0 34.0 113.0 65.0 91.0 56.0 64.0 56.0 100.0 45.0 88.0 4.0 3.0 4.0 4.0 4.0 4.0 5.0 3.0 5.0 4.0 6.0 4.0 4.0 3.0 4.0 4.0 3.0 4.0 4.0 3.0 5.0 5.0 5.0 4.0 -0.40583372345636803 0.02824036873330045 0.04901805310036017 GO:0043933 protein-containing complex subunit organization biological_process 27.462086140943928 28.015756798906413 27.442781234336227 27.541835038319178 27.220531084592746 27.445234735857852 26.685462877989067 28.26442361729607 27.498033913075915 27.98691108464805 27.34001185474685 28.15645599938656 27.664815074520675 28.052385786585926 27.92135175151089 28.258330996775175 26.96428799282768 28.11135135174648 27.40217179653316 28.298460250522385 27.559025502680807 27.559818035231 28.177783138648227 28.30640726301845 27.017176387636123 27.84738870989355 98.0 51.0 87.0 132.0 82.0 109.0 100.0 89.0 131.0 120.0 123.0 101.0 137.0 129.0 105.0 133.0 142.0 123.0 118.0 89.0 140.0 109.0 95.0 106.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 3.0 3.0 5.0 3.0 4.0 3.0 4.0 4.0 3.0 3.0 3.0 4.0 4.0 -0.5536706579624848 0.0018227351663913985 0.005134928866041682 GO:0043952 protein transport by the Sec complex biological_process 21.680269917558533 22.13613730007216 21.70684518847405 22.66685081065343 21.922856371616195 21.557186590500827 21.145339201116816 20.96165970935037 21.212663741939693 21.657526212747324 21.792196833205786 21.756128732152767 21.855822935664786 21.794610198162193 20.01878877675648 22.01248175996545 21.32539107648003 21.512313215565015 21.292782270178094 22.94381667176809 21.36018995286328 20.425382894051975 22.33476771140165 22.58932058618063 22.634295540081855 23.25768059475699 5.0 8.0 4.0 5.0 10.0 5.0 6.0 10.0 9.0 10.0 12.0 7.0 6.0 6.0 10.0 6.0 7.0 12.0 9.0 6.0 10.0 8.0 16.0 19.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.45586738251362746 0.24821307898992373 0.31935043564889154 GO:0044036 cell wall macromolecule metabolic process biological_process 23.49851267918289 25.5200043712392 24.61851683416264 25.314974814671288 23.95965790080077 25.39005565155739 22.2804673195042 26.169816688054304 22.796322016039838 25.267659341383013 22.857026621637807 25.632307962901358 23.818556059659272 25.989837344340426 23.678268936976703 25.58646303829068 23.05249029529159 24.88801437125124 23.53615232108523 25.61176243261412 23.05535458415903 25.111535443108448 23.236826603339487 25.67200896149745 23.573212238525265 25.04924916141784 39.0 50.0 26.0 41.0 19.0 63.0 15.0 55.0 24.0 59.0 35.0 57.0 27.0 66.0 20.0 54.0 36.0 54.0 27.0 49.0 21.0 61.0 33.0 52.0 3.0 3.0 1.0 2.0 2.0 2.0 1.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 1.0 2.0 2.0 2.0 3.0 3.0 2.0 3.0 -2.0214916920563084 3.225641456243767e-05 0.0005099643033035255 GO:0044038 cell wall macromolecule biosynthetic process biological_process 23.312591966714017 25.47542843323637 24.420044297547694 25.267693901134983 23.95965790080077 25.371959182016464 22.21789588098353 26.15593702317052 22.796322016039838 25.24008355357119 22.677763405351786 25.30856179449298 23.44894701414511 25.983711716670488 23.54611306367377 25.55973561702586 22.985522026707358 24.86068789874241 23.53615232108523 25.603764877990823 22.701933584827515 25.103167548885995 22.126712077842285 25.648792007651863 23.4938818992912 25.024318343476946 32.0 46.0 26.0 40.0 18.0 62.0 15.0 53.0 20.0 46.0 27.0 54.0 24.0 58.0 17.0 47.0 36.0 53.0 22.0 48.0 17.0 57.0 29.0 48.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -2.1628364665223536 3.225641456243767e-05 0.0005099643033035255 GO:0044205 'de novo' UMP biosynthetic process biological_process 23.97462864466691 24.79972859770641 23.881902597163318 24.089123514452176 22.418949423093753 23.464499646759247 23.677815927010744 24.66202841813073 23.37270734091205 24.659066556488327 24.272959669446106 25.03772555360919 24.6292472456813 25.26688943264545 24.524964546903924 25.216277451570765 24.27916618263195 25.047192512173662 22.488310260632854 24.367570407237157 22.791397985800074 23.848813435601567 23.12751160541028 25.54569867880807 25.233211934507562 25.01060302531259 19.0 35.0 8.0 24.0 22.0 74.0 25.0 68.0 27.0 57.0 40.0 66.0 45.0 54.0 35.0 72.0 26.0 43.0 21.0 38.0 27.0 65.0 45.0 64.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8250999530394978 0.009374768459434895 0.01937038251220985 GO:0044206 UMP salvage biological_process 25.09359164521056 25.37853437890985 24.803012724621897 24.354441634451337 24.10255993643301 24.868181488831787 24.619721156203237 25.30438968116932 24.58846956013884 25.67902279020073 25.533366668922838 25.835429605546075 25.17458054226963 25.28337286485929 23.840081821596666 25.07422232232391 24.69886519588473 25.11552973196702 25.94942552275021 25.361795031594962 26.250167880232148 25.294266423573056 24.653898378924694 26.08049256919204 24.915886175701495 25.534793766345768 23.0 17.0 15.0 21.0 28.0 21.0 31.0 27.0 28.0 35.0 31.0 16.0 28.0 20.0 30.0 29.0 41.0 37.0 29.0 19.0 35.0 32.0 34.0 27.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.28494273369929246 0.0832645166635504 0.12534875367444018 GO:0044208 'de novo' AMP biosynthetic process biological_process 24.520312370610966 25.627499718591107 24.880314870152997 25.032424545501648 24.95627157187362 24.775918087598292 23.395723398421048 25.43183028439709 23.87822608664127 25.22248487462256 24.218131805955423 25.54791284227184 25.54518622017761 26.18801216476384 24.285561472395074 26.37596091867261 23.943333737250104 25.62783309761964 24.45158322403048 25.70087206711717 24.42723585908648 25.602553607152227 24.700495024042247 26.040228556383056 24.326533008081203 25.08762868326233 40.0 37.0 38.0 41.0 26.0 49.0 21.0 57.0 33.0 55.0 47.0 49.0 36.0 62.0 32.0 55.0 39.0 62.0 41.0 52.0 36.0 54.0 40.0 57.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1071873479801404 0.0001748865925420931 0.0008236168584623857 GO:0044209 AMP salvage biological_process 25.610138797819875 25.90871207574503 25.49793885356564 25.49321753699018 24.549260740105037 25.70663895570907 26.52360506510185 26.049216351240037 25.351914951244503 26.28496184628836 26.163966344309454 25.96459083549097 26.421709164188066 25.27661066518109 24.772217260530947 26.150844968552853 25.297694592590236 26.173673682477016 25.83407077213005 25.926674973195446 24.899071278426213 25.603659423623125 25.117675930496826 26.01032318047843 25.285302811298862 25.932604445499123 33.0 25.0 23.0 28.0 34.0 34.0 31.0 32.0 39.0 37.0 41.0 25.0 33.0 37.0 32.0 39.0 38.0 43.0 28.0 29.0 32.0 32.0 36.0 38.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.2985732779251542 0.0940685547103812 0.1379524750629327 GO:0044210 'de novo' CTP biosynthetic process biological_process 24.055351011071405 24.904798575753297 22.61871073358945 24.34085116311393 21.768958727453818 24.699317331658893 23.22904053685214 24.95673234179031 23.796499232371808 25.07612495619625 24.367970806962344 25.061576271413532 24.82119146039807 24.748321867404947 24.26938127035038 25.0627485856445 23.975929990949588 24.61112899578305 24.900019038701892 24.770773246395148 23.99732608011401 24.555583194417906 24.018740731477926 25.729180963851594 24.37243290690597 24.72520076044816 17.0 23.0 9.0 22.0 18.0 38.0 25.0 48.0 26.0 37.0 33.0 30.0 32.0 39.0 21.0 39.0 45.0 44.0 31.0 29.0 35.0 42.0 29.0 40.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.849447564681892 0.0012242832644312096 0.0037265988146589013 GO:0044211 CTP salvage biological_process 21.21108357478105 20.94952247257843 22.32373863163535 20.648770657652076 22.159963707627405 21.422980767259947 20.79626891761352 19.980866886772827 16.375003804514847 18.388374377896575 21.120225792245343 21.463753059622128 21.27696485147666 20.890998300439342 20.278315925299214 21.2621317831787 20.44622012547341 19.981163667880253 19.7538779863368 20.910472804388327 21.78650681382977 20.480097660230907 21.127248804653565 22.14948282999618 21.505229827247394 20.927593983130397 6.0 4.0 4.0 5.0 3.0 2.0 1.0 1.0 4.0 6.0 5.0 2.0 1.0 5.0 3.0 5.0 3.0 3.0 6.0 3.0 6.0 8.0 5.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.2615611022026201 0.5253727863737021 0.6008633207515945 GO:0044237 cellular metabolic process biological_process 37.9677677586457 38.649885620421394 38.04596944310143 38.01475961326409 37.699457662037204 38.58153636953042 37.59552880488521 38.81490118977253 37.591411865847725 38.56270055633821 38.13500459678843 38.569858058770315 38.091931916299295 38.21129586052428 38.37161761292685 39.00783330999499 37.516381601903795 39.06526699070109 38.54344238391944 38.840080175005404 37.90036730240305 38.51457680631234 37.79719330851545 38.75060813912947 37.924819062957546 38.52487980709859 127095.0 125940.0 123860.0 154653.0 142235.0 200790.0 160848.0 186185.0 166196.0 188496.0 178440.0 144150.0 179545.0 189318.0 140324.0 193539.0 221418.0 210611.0 162258.0 159009.0 169498.0 176151.0 171069.0 190082.0 22.0 22.0 22.0 22.0 22.0 22.0 23.0 22.0 22.0 22.0 21.0 23.0 23.0 22.0 22.0 22.0 22.0 22.0 22.0 22.0 22.0 22.0 22.0 22.0 -0.6821178617756942 0.0002755038114342687 0.0011655212090507369 GO:0044238 primary metabolic process biological_process 35.35519962654928 35.99735138975585 35.444582431582326 35.35129870067544 35.12441184929112 35.92369533117318 34.99690362278064 36.14902878199844 34.9801838002384 35.908840814931175 35.497559229203965 35.963425648238484 35.48150704441864 35.57723285239559 35.72718748509707 36.35232666500159 34.898346553262755 36.38765851317514 35.914584509183406 36.18189641162578 35.32433320755629 35.869971527817675 35.19661000443299 36.096623775970244 35.3059606137342 35.8808955928607 21235.0 20981.0 20927.0 26087.0 23666.0 33473.0 26689.0 31357.0 28208.0 31904.0 30271.0 24255.0 30225.0 32169.0 23321.0 32910.0 37389.0 35009.0 27049.0 26876.0 28366.0 29761.0 28419.0 32034.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 -0.6421517632065701 0.00034415785384659113 0.0013990521224773477 GO:0044248 cellular catabolic process biological_process 31.51487561293109 31.552246387527408 31.353688864065408 31.000183213426155 31.270145094661032 31.67074106081383 31.11768885383937 31.80049996512529 31.402643564664594 31.307297216715998 31.706747780059107 31.39590420137216 31.50762123475038 30.939672810287533 32.00916493845778 31.82087993846235 30.917418209195052 31.92748416341321 31.992576176992866 32.10333254191846 30.74032820659853 31.492555752037635 31.90984971294793 31.396587097502948 31.623844270093304 31.275262218448766 906.0 819.0 1073.0 1206.0 1192.0 1335.0 1475.0 1139.0 1516.0 1222.0 1451.0 940.0 1608.0 1127.0 1051.0 1113.0 2019.0 1680.0 1260.0 967.0 1405.0 954.0 1351.0 1134.0 13.0 12.0 13.0 15.0 14.0 14.0 15.0 15.0 15.0 16.0 15.0 14.0 15.0 15.0 15.0 15.0 15.0 16.0 14.0 15.0 15.0 15.0 14.0 16.0 -0.03737077459631877 0.8173613313851769 0.8543274217493305 GO:0044249 cellular biosynthetic process biological_process 34.64913553993373 35.25218895335432 34.635644168530945 34.62654456308865 34.26111170208959 35.155908316110754 34.290513127658855 35.403677815212085 34.339320249156444 35.18179948959051 34.83147294035453 35.219476065551326 34.81371639238077 34.873781315325644 35.0052929254972 35.5914361826703 34.20272269397622 35.61044266033707 35.26038390835283 35.42970988788491 34.60828078899141 35.090149461526856 34.56113834095557 35.402019391744645 34.57293509324962 35.140271663119066 13239.0 12963.0 12215.0 15729.0 14602.0 20457.0 16651.0 19255.0 17062.0 19661.0 18380.0 14991.0 18629.0 19496.0 14545.0 19943.0 23016.0 21989.0 16560.0 16021.0 17630.0 18497.0 17613.0 19743.0 17.0 17.0 18.0 18.0 18.0 17.0 18.0 17.0 17.0 18.0 16.0 18.0 18.0 18.0 19.0 18.0 18.0 17.0 19.0 17.0 18.0 18.0 19.0 18.0 -0.6030534134205894 0.0005320055051392492 0.0019244720881558927 GO:0044255 cellular lipid metabolic process biological_process 29.200891260440745 29.08304470620077 28.53433417860425 26.19379318344781 26.49094121578407 27.347161648213593 28.789886004114212 29.09319552408455 29.701181973588586 30.136408257942023 29.18465701985669 29.714768479492324 29.67009284954198 28.731618051350733 29.504744707451035 28.493761603830336 28.905451322266487 29.179645968157335 29.675906382077702 29.313881146267533 29.22336634407536 28.581953566325964 29.674210448482384 29.10548077047185 28.93937538192727 29.68661182769556 242.0 107.0 117.0 227.0 366.0 329.0 519.0 380.0 434.0 359.0 473.0 278.0 415.0 303.0 365.0 408.0 581.0 466.0 324.0 289.0 478.0 322.0 433.0 356.0 6.0 7.0 7.0 8.0 8.0 7.0 8.0 7.0 8.0 8.0 8.0 7.0 8.0 7.0 9.0 8.0 8.0 8.0 7.0 8.0 8.0 8.0 9.0 8.0 0.11784655423997492 0.6033317722918665 0.6716842567531217 GO:0044260 cellular macromolecule metabolic process biological_process 32.093100300561986 31.63077189512757 31.342473443795523 31.015502764934677 30.915929468281284 31.584477444358157 31.618356995108947 31.69547933494148 32.20760881725643 31.32232499125165 32.25458290962357 31.862733421918946 32.244726363661535 31.626327887639718 32.431328850618065 31.864175492446016 31.703591734343057 31.379778215640076 32.79154281218333 31.972279998301268 31.944809563550248 31.383906639017958 32.62129140952392 31.883945463921236 31.9995222582491 31.68246195456027 1646.0 1303.0 1128.0 1859.0 1775.0 1892.0 2262.0 1721.0 2352.0 2038.0 2244.0 1697.0 2614.0 1938.0 1757.0 1733.0 2758.0 2497.0 1831.0 1283.0 2213.0 1803.0 2112.0 1897.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 0.4623284054344161 0.02824036873330045 0.04901805310036017 GO:0044262 cellular carbohydrate metabolic process biological_process 28.41812171940552 28.38596903137632 28.81108908345386 28.20911506087564 28.41416191772717 28.317593065737327 27.794310783072792 28.85088572933629 27.75387303845661 27.984448684083272 28.36016810906135 28.875499965960532 28.79438213302361 28.55072154052761 28.6191581577909 28.75522286991791 27.22999599989571 27.681253491160998 29.64097571519711 28.37450606401086 28.569572269738945 28.393431198580622 26.992689021012307 28.026314678558606 27.994613387544145 28.09530940398307 292.0 280.0 290.0 234.0 265.0 360.0 241.0 282.0 332.0 362.0 355.0 240.0 413.0 394.0 270.0 324.0 537.0 338.0 267.0 263.0 203.0 250.0 311.0 272.0 6.0 6.0 7.0 7.0 8.0 6.0 8.0 6.0 9.0 8.0 7.0 6.0 6.0 7.0 9.0 7.0 8.0 7.0 8.0 6.0 8.0 7.0 8.0 6.0 0.032152688029199794 0.8173613313851769 0.8543274217493305 GO:0044264 cellular polysaccharide metabolic process biological_process 26.371837595224648 25.84583117589598 27.320522975853148 25.540054574675285 26.55198719944793 25.12121353406028 25.57930521936652 26.46764385045234 25.409572419663483 25.477328841883217 26.568438196796432 26.272936740021944 26.624054049763345 26.284110239738393 26.512162823201546 26.281058514823194 26.01466915814512 24.981783481946998 26.508773851932425 25.81566869588284 25.795348633389416 26.13908800859007 25.063614993176657 25.027004342120534 26.910322685699573 25.69346405714199 57.0 65.0 59.0 40.0 86.0 90.0 91.0 69.0 137.0 80.0 125.0 58.0 112.0 81.0 105.0 77.0 180.0 75.0 73.0 65.0 65.0 46.0 126.0 60.0 5.0 5.0 3.0 5.0 4.0 6.0 5.0 6.0 5.0 5.0 7.0 5.0 5.0 5.0 5.0 6.0 6.0 4.0 5.0 5.0 5.0 5.0 5.0 7.0 0.5260064193286667 0.043308142810791976 0.0706517153305469 GO:0044265 cellular macromolecule catabolic process biological_process 24.938458117724075 24.93950348549389 24.05535297587515 24.601010635410127 23.342196970182627 25.219542924488486 24.85750913970352 24.758053192289392 25.19578966164905 23.84959899711413 25.41802055262136 25.19064211634965 25.507315913934068 25.362101013309086 24.817037876323162 25.08251947888074 24.31608532652955 24.787724629229693 25.504719345008944 24.877805975873308 24.46984747778828 23.961423533740025 25.18355967031691 25.9780555543722 25.14171607707684 24.1746291086468 40.0 52.0 15.0 67.0 52.0 50.0 59.0 38.0 65.0 76.0 61.0 58.0 54.0 74.0 38.0 77.0 91.0 63.0 35.0 34.0 66.0 74.0 58.0 47.0 2.0 3.0 2.0 2.0 3.0 2.0 3.0 4.0 2.0 2.0 3.0 3.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 2.0 3.0 3.0 -0.001045367769815897 0.7290344895388041 0.7743276961229171 GO:0044267 cellular protein metabolic process biological_process 30.897494807687522 30.225386635660552 29.970960618837534 29.531531105941163 29.6189813285237 30.259733461029352 30.390026303983912 30.20882159746238 31.071088272749467 29.82966312805161 31.05135973735861 30.47264680294138 31.024280125405802 30.190458070023972 31.296675047037052 30.4780353088456 30.495857423448854 29.962506773990608 31.6389775218005 30.583757783898395 30.69944516677381 30.018985904622003 31.47940493375329 30.497675715001954 30.761000431015074 30.315932102682318 513.0 255.0 305.0 531.0 524.0 437.0 751.0 442.0 689.0 524.0 636.0 332.0 889.0 421.0 535.0 378.0 817.0 721.0 590.0 303.0 729.0 366.0 574.0 490.0 3.0 4.0 3.0 3.0 5.0 3.0 5.0 4.0 4.0 3.0 5.0 4.0 4.0 3.0 3.0 2.0 5.0 4.0 4.0 3.0 4.0 3.0 5.0 3.0 0.6721081720269702 0.007911788680711459 0.016907384030013527 GO:0044270 cellular nitrogen compound catabolic process biological_process 29.278206217650236 29.787781012465054 29.418102002846503 29.19663500348531 29.224576865101533 29.86382349552785 28.809655489744266 30.05666072432535 28.933078691549568 29.58894233827909 29.358213628013324 29.57294094307845 29.17272203414725 29.146701730054804 29.893609602049484 30.115448334659987 28.65863861419355 30.274405269851016 29.77736010512702 30.18965638975207 28.66210668266375 29.691958832738692 29.502011571485518 29.730151463621112 29.309235922333336 29.51742383637153 210.0 201.0 215.0 281.0 261.0 338.0 313.0 292.0 314.0 299.0 294.0 223.0 355.0 280.0 230.0 295.0 418.0 376.0 264.0 243.0 297.0 259.0 288.0 279.0 3.0 3.0 4.0 3.0 6.0 4.0 5.0 5.0 3.0 4.0 4.0 4.0 5.0 4.0 4.0 4.0 4.0 4.0 6.0 4.0 3.0 3.0 4.0 4.0 -0.5095747948148173 0.007911788680711459 0.016907384030013527 GO:0044271 cellular nitrogen compound biosynthetic process biological_process 33.092402827209874 33.6250855440338 33.03184557786942 33.011371497439306 32.65680749216451 33.543246961629855 32.72153462878413 33.77536889774219 32.82448888288853 33.534416919682386 33.28026824445642 33.58760900473585 33.251186379445905 33.254442382503875 33.452480154787324 33.96259951078142 32.64918115471458 33.96040475532371 33.71417079530546 33.810609533632146 33.03357878767701 33.47521212392118 33.05570550150109 33.77916832160201 33.018073244091326 33.517993465644935 4259.0 4034.0 3843.0 4963.0 4683.0 6314.0 5403.0 5950.0 5460.0 6110.0 5829.0 4583.0 6034.0 5982.0 4681.0 6103.0 7291.0 6945.0 5291.0 4942.0 5651.0 5679.0 5609.0 6143.0 10.0 11.0 8.0 10.0 9.0 10.0 10.0 10.0 9.0 10.0 10.0 11.0 10.0 10.0 9.0 10.0 9.0 11.0 8.0 8.0 9.0 11.0 10.0 11.0 -0.5326827168239276 0.0012242832644312096 0.0037265988146589013 GO:0044272 sulfur compound biosynthetic process biological_process 27.41439021269534 26.21344753031445 25.44441186587384 24.955266322746077 24.87614451708746 25.588309729940534 27.53236222899837 26.38122893897689 28.10107544302613 26.42102288206277 28.13077706950609 26.46307502785875 27.7363997632928 26.11966189540857 27.815060891474037 26.20817205412721 27.12404895031981 26.30823948395309 27.360706861486012 26.537440297345448 26.412547835403064 25.945006753389233 27.53147132426125 26.60804469513437 27.79230869386221 26.309293123246487 62.0 51.0 58.0 68.0 114.0 117.0 123.0 78.0 121.0 112.0 123.0 85.0 115.0 107.0 81.0 103.0 167.0 139.0 87.0 78.0 118.0 111.0 119.0 89.0 6.0 5.0 5.0 6.0 6.0 6.0 6.0 6.0 8.0 8.0 6.0 7.0 6.0 7.0 6.0 6.0 9.0 6.0 6.0 8.0 7.0 7.0 8.0 7.0 1.2009426823808909 0.009374768459434895 0.01937038251220985 GO:0044275 cellular carbohydrate catabolic process biological_process 25.79847385392819 25.18121202112421 25.55317337274843 25.168383701605364 25.28753257272097 25.41027967455091 25.27060359981369 25.851400471859087 25.316214390125502 24.23971668799179 25.616544528175574 26.12641248016487 26.402843182256237 25.012272761593014 26.087945103308744 25.86395135551843 23.39956688639911 24.299670325454866 27.504903929816976 24.66522167457206 26.18652658346221 24.97530360341689 24.275788669521408 24.16286052699075 24.11502799621494 24.670531774998498 57.0 43.0 52.0 33.0 35.0 51.0 26.0 37.0 34.0 59.0 49.0 34.0 62.0 63.0 28.0 40.0 70.0 51.0 42.0 36.0 26.0 31.0 29.0 42.0 2.0 2.0 2.0 2.0 3.0 3.0 4.0 2.0 4.0 3.0 4.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 4.0 3.0 3.0 2.0 3.0 3.0 0.6172618328039796 0.27265646879500405 0.34545713000625894 GO:0044281 small molecule metabolic process biological_process 35.24985511457135 35.87903636811542 35.3147165064149 35.22100610742189 35.04039405678613 35.80404052001814 34.885094625632355 36.01333923991938 34.838392162283434 35.77162339300333 35.39462136073894 35.84434170144037 35.341919020999406 35.424086059715755 35.64671960915525 36.24012121764267 34.778184684116475 36.311557609223094 35.86872888530785 36.09370777383121 35.14864316137332 35.745524096702255 35.11301473527288 35.975389137092705 35.21191513513339 35.74333519901025 18276.0 18491.0 19086.0 23441.0 20535.0 30356.0 23102.0 28499.0 24581.0 28733.0 26605.0 21681.0 26497.0 28985.0 20319.0 30131.0 32861.0 31241.0 24408.0 24423.0 25364.0 26941.0 24856.0 28939.0 10.0 9.0 10.0 11.0 11.0 10.0 12.0 11.0 11.0 10.0 10.0 10.0 12.0 10.0 12.0 11.0 10.0 10.0 10.0 10.0 11.0 10.0 11.0 11.0 -0.6291812535440684 0.0005320055051392492 0.0019244720881558927 GO:0044282 small molecule catabolic process biological_process 29.54515557628069 28.294378375173192 28.704660812488278 27.98734199518583 29.13397825079988 28.452338174618124 29.230825585938486 28.052786860253164 29.702267688214558 27.70033647757488 29.857134487902737 28.228547376938337 29.634151376357355 27.452947845923838 29.711666580345145 28.14641100575233 28.91092248868485 27.918400327478288 30.19041977861577 29.675327412314267 28.71634746891139 28.57902257030108 30.098655713964845 27.737325395069647 29.68781250750957 28.108167683215004 150.0 108.0 229.0 181.0 252.0 193.0 330.0 162.0 360.0 190.0 346.0 127.0 337.0 162.0 227.0 125.0 449.0 326.0 265.0 157.0 296.0 97.0 296.0 168.0 5.0 5.0 6.0 7.0 5.0 5.0 7.0 7.0 5.0 7.0 6.0 7.0 8.0 7.0 7.0 6.0 5.0 6.0 6.0 7.0 6.0 6.0 6.0 7.0 1.2507772011074962 0.0001386794054294884 0.0007006959432226783 GO:0044283 small molecule biosynthetic process biological_process 30.561373603376268 31.55660684044857 30.865416430386343 30.84833044709936 30.61371267281579 31.46199225310049 30.04673617891244 31.66167047209288 29.705160031954478 31.42331593252861 30.4442277242018 31.60796546788938 30.49911503860282 31.14214207383255 31.1112528476871 31.95094064447559 30.017837555279414 32.07272521262997 31.45365577759336 31.678931628305502 30.53810465731184 31.329350550206946 30.199985664643695 31.73793854419492 30.28861791567717 31.33310483008807 894.0 1016.0 978.0 1309.0 903.0 1724.0 959.0 1661.0 1090.0 1638.0 1230.0 1250.0 1232.0 1716.0 895.0 1858.0 1621.0 1598.0 1199.0 1374.0 1216.0 1677.0 1099.0 1644.0 5.0 4.0 4.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 6.0 5.0 6.0 5.0 6.0 6.0 5.0 5.0 5.0 5.0 6.0 5.0 6.0 -0.995233237072302 0.0001748865925420931 0.0008236168584623857 GO:0044364 disruption of cells of other organism biological_process 24.81605134339345 24.97140687963764 24.363629888026622 24.714195505546176 19.848768692520927 21.65024920379642 25.037947312028518 24.710468575037204 24.44244791120097 25.274824560357967 26.09680608932921 26.22056697751924 24.722364116734518 25.612676902639862 NA 22.04516694044829 25.242223584090837 24.480930305412826 24.886857525719105 25.77629837090432 20.795047110271746 NA NA 23.95799338666023 25.37847842155172 24.93068428517233 10.0 10.0 10.0 10.0 10.0 21.0 10.0 10.0 10.0 24.0 10.0 14.0 NA 20.0 10.0 20.0 10.0 10.0 10.0 NA NA 20.0 10.0 10.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 NA NA 2.0 2.0 2.0 -0.15535553624419052 0.72477122130619 0.7743276961229171 GO:0044391 ribosomal subunit cellular_component 30.178709032240878 30.27504508492101 29.797295090096608 29.674161611265358 29.849322877037984 30.51046179352385 29.5057820143656 30.27124785399932 30.346662911494388 29.90691098757237 30.11352851872157 30.304540819464393 30.25939369804122 30.298372918870825 30.79647373835677 30.45566010059681 29.681264155912032 30.164588584068536 30.49096416623801 30.442449399983737 30.06249013146102 30.29984005968576 30.682406462851162 30.55854640700653 29.939908434470052 30.181340347416192 257.0 127.0 176.0 270.0 281.0 221.0 408.0 198.0 354.0 248.0 313.0 142.0 455.0 215.0 293.0 185.0 389.0 334.0 309.0 171.0 364.0 174.0 295.0 238.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.09633605268013312 0.3263484733220724 0.4012639356708831 GO:0044419 interspecies interaction between organisms biological_process 25.538224582706114 25.724768868847605 25.10230142481243 25.433558929612413 23.11384033175216 23.2929065346143 25.88005245492587 25.879921398939643 25.764530670508734 26.10202904544584 26.90711150453623 27.03671574473897 25.74035853887576 26.39717723678698 23.072568510053248 22.828834028209403 25.99808179040813 25.58059298750099 25.668602874139644 26.660291471253057 22.816302308365326 20.157241070134834 24.331567820254172 24.93741279206719 26.276617672023693 25.660198157386407 19.0 26.0 21.0 23.0 21.0 58.0 86.0 31.0 22.0 56.0 29.0 50.0 4.0 38.0 19.0 36.0 19.0 22.0 19.0 3.0 9.0 49.0 22.0 22.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 4.0 4.0 3.0 4.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 3.0 3.0 -0.18654428614149055 0.8624902301359216 0.8917877441670506 GO:0044421 extracellular region part cellular_component 22.958013456785043 23.367416394678912 22.98035149385448 23.357548629353442 20.307225551340725 22.495995328042675 22.869197742154217 23.321468793990626 22.316250288786687 23.425353132497314 24.44557228692218 24.276550796662146 23.34082112700853 23.76944173692813 20.80874578380901 22.44614275033133 23.51095260308877 23.60591760601227 23.26538637986032 24.139907209786497 18.9458451460548 18.36696111623289 21.624101668928155 22.92391933220313 23.76314458170676 23.463250785350127 9.0 16.0 5.0 14.0 5.0 16.0 8.0 10.0 16.0 19.0 10.0 17.0 7.0 22.0 13.0 24.0 10.0 19.0 3.0 3.0 5.0 15.0 8.0 12.0 3.0 2.0 3.0 3.0 2.0 2.0 2.0 1.0 2.0 2.0 3.0 4.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 1.0 2.0 3.0 2.0 2.0 -0.4094029378938693 0.2040238704744366 0.2705863871967023 GO:0044422 organelle part cellular_component 30.287186154370804 30.359037770901658 29.865658166275892 29.82613467567613 29.945523980835837 30.528154053927558 29.76795730979964 30.346072402010716 30.38532756486413 29.97708998637141 30.316092882404185 30.41854644609807 30.477349716827412 30.43180723283623 30.8924398016579 30.517752599900465 29.717621417106525 30.220292313785077 30.52564293228921 30.57490067912365 30.11713636684083 30.340729957023672 30.71076439219593 30.6159467786837 30.182654049270486 30.305939170652838 293.0 158.0 220.0 309.0 317.0 259.0 449.0 234.0 421.0 317.0 389.0 197.0 501.0 256.0 328.0 249.0 435.0 383.0 336.0 199.0 394.0 219.0 334.0 273.0 4.0 2.0 2.0 5.0 3.0 3.0 5.0 4.0 4.0 4.0 5.0 2.0 4.0 3.0 3.0 4.0 4.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 -0.07185161653085359 0.3864762307712327 0.4687291895068012 GO:0044424 intracellular part cellular_component 33.28490996855236 33.3768136974538 33.08083342465575 32.79964712970069 32.922178641857826 33.366566573217426 32.90893723996457 33.433288893784656 33.369453977994425 33.29784678882885 33.37761227012753 33.54043222228592 33.36871399053494 33.21862025234248 33.57787004517246 33.52438781015213 32.78959470784445 33.346737600798576 33.66296070601446 33.53966390815614 33.395095057434865 33.328288433732844 33.519329503573516 33.567712580748356 33.14433793687239 33.40387203166081 3335.0 2616.0 2814.0 3899.0 3810.0 4280.0 4504.0 4034.0 4639.0 4378.0 4524.0 3152.0 5102.0 4133.0 3537.0 4089.0 5423.0 5063.0 4106.0 3474.0 4549.0 3941.0 4312.0 4401.0 14.0 14.0 11.0 16.0 16.0 15.0 18.0 14.0 19.0 14.0 18.0 13.0 15.0 12.0 16.0 15.0 20.0 17.0 10.0 12.0 16.0 12.0 19.0 19.0 -0.0919037289014355 0.4884223166225936 0.5675521891480417 GO:0044425 membrane part cellular_component 29.99527002941087 30.03805247898665 29.882949348434657 29.7196914116222 30.03991552920024 29.686550410177933 29.53644385567819 29.912367700559034 29.589389924155807 29.77631473226861 30.102804140698172 30.13055472716047 30.370378602598358 30.210443688367906 30.052421035290784 30.38404395924129 29.742628201835046 30.005843573442537 30.172128061782512 30.219763456582108 30.0088273727535 29.72600269024413 29.968307431389647 30.392350858330694 30.240988346292795 30.042982766312853 686.0 775.0 665.0 848.0 568.0 1054.0 739.0 978.0 803.0 1112.0 987.0 1033.0 772.0 1094.0 630.0 1010.0 934.0 1110.0 791.0 882.0 782.0 1163.0 921.0 1170.0 5.0 5.0 6.0 6.0 5.0 8.0 7.0 7.0 6.0 7.0 6.0 6.0 6.0 6.0 5.0 6.0 6.0 6.0 5.0 6.0 5.0 5.0 6.0 7.0 -0.04278244957577826 0.7290344895388041 0.7743276961229171 GO:0044427 chromosomal part cellular_component 20.91801221724598 21.785207845890287 21.302882351593247 21.440293587879776 21.276390670831336 22.709267198040614 20.6960329809095 20.87862696983612 19.717243849686625 21.002926996763847 21.497877793352664 22.453270610822255 21.85930162674964 22.13314409665805 21.406607777844133 21.23155717321445 18.416170961325747 21.554103908386608 19.083143107707347 21.951465389477654 21.54385518954567 21.285138483982326 19.29881658735413 22.323284877500896 20.88342697070935 20.853116924470754 8.0 10.0 3.0 16.0 4.0 9.0 5.0 12.0 10.0 11.0 10.0 13.0 7.0 14.0 3.0 8.0 7.0 16.0 7.0 10.0 4.0 12.0 9.0 7.0 2.0 1.0 1.0 3.0 2.0 1.0 1.0 1.0 2.0 1.0 1.0 1.0 2.0 2.0 2.0 3.0 1.0 3.0 2.0 3.0 1.0 1.0 2.0 2.0 -0.867195628644307 0.03266344168491133 0.055917661485280296 GO:0044428 nuclear part cellular_component 22.152691225683277 23.76438757811424 22.83867797297859 24.41832574066875 21.171602097216066 16.418236326171787 19.88944193063137 23.716215741196777 22.61897812804043 23.38493507990035 21.361014485558847 23.826313624575892 21.25538617542543 24.042764258599185 20.75672794000573 23.104871170548066 21.944509148954435 23.003317180694328 22.97054408614077 24.738901191148358 19.544833952409707 22.937188035768585 23.275931450920762 23.69240957637659 23.02405415330481 24.550763017118864 3.0 4.0 2.0 3.0 3.0 3.0 5.0 6.0 2.0 4.0 2.0 2.0 1.0 4.0 5.0 13.0 5.0 6.0 1.0 4.0 5.0 4.0 2.0 7.0 3.0 4.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 4.0 2.0 2.0 1.0 4.0 4.0 9.0 4.0 6.0 1.0 4.0 5.0 4.0 2.0 6.0 -1.611696352430961 0.0018227351663913985 0.005134928866041682 GO:0044429 mitochondrial part cellular_component 22.60623262794601 23.85536879047641 23.122987783171038 24.396376595437086 21.39114813077001 20.075717830115188 20.878713628740805 23.825062982007278 23.174575134846073 23.550910865322066 22.55420890267613 24.274998259701405 21.44700478329129 24.205245123612226 23.51127487772025 23.65756530224912 21.38875533392935 22.137662304200763 22.52786290403429 24.99218988131275 23.12170793139628 23.0144182813283 22.498412174080812 22.97931317105279 23.022185492727356 24.52730031780697 3.0 2.0 3.0 2.0 5.0 5.0 7.0 8.0 8.0 13.0 6.0 3.0 8.0 3.0 2.0 7.0 8.0 6.0 2.0 5.0 2.0 2.0 5.0 7.0 2.0 1.0 3.0 2.0 3.0 4.0 5.0 6.0 5.0 5.0 5.0 3.0 6.0 2.0 1.0 4.0 4.0 4.0 2.0 3.0 2.0 1.0 4.0 4.0 -1.249136162530398 0.01531382171343201 0.02967647437634029 GO:0044444 cytoplasmic part cellular_component 31.34690020419497 31.334389140294018 30.83066215087288 30.716290983732147 30.630723267557077 31.313357061481472 30.96631992983909 31.359678135665998 31.645283104096023 31.171253564379267 31.496205602744627 31.52795138605847 31.51393005343953 31.297432429560928 31.80292459123614 31.49173658284766 30.952595754957798 31.29604268366109 31.4824088886198 31.482153546741642 31.20201537179721 31.24525194973181 31.83300445428795 31.646698134923266 31.2363323299826 31.268339830389014 586.0 317.0 437.0 627.0 739.0 573.0 940.0 511.0 873.0 638.0 817.0 379.0 1070.0 507.0 701.0 490.0 909.0 793.0 761.0 432.0 895.0 447.0 790.0 607.0 16.0 12.0 15.0 16.0 17.0 13.0 15.0 12.0 22.0 16.0 21.0 15.0 18.0 16.0 18.0 13.0 18.0 21.0 13.0 13.0 19.0 13.0 19.0 17.0 0.012511063900952024 0.9539596927720386 0.9577970205788449 GO:0044445 cytosolic part cellular_component 26.5422572767164 27.87880591466299 26.16404252391915 26.925934064936804 26.913022089366684 27.863365491273125 26.213946584839192 27.18094461625505 27.23105047904565 27.19425371412023 26.75901460837109 28.074508824490238 26.57570209643093 27.77359000212429 26.676926935637663 28.23265710403274 25.875779480701734 28.67808750574195 25.99293419446371 27.415457912766428 26.648797166738003 28.151862016522678 26.55740214754349 28.580309332800546 26.29958286550823 27.14746491344513 18.0 27.0 20.0 41.0 22.0 30.0 35.0 29.0 26.0 31.0 28.0 22.0 41.0 29.0 22.0 37.0 31.0 39.0 20.0 31.0 30.0 28.0 31.0 32.0 4.0 5.0 3.0 4.0 6.0 6.0 7.0 3.0 6.0 4.0 5.0 4.0 5.0 4.0 5.0 4.0 5.0 7.0 5.0 2.0 6.0 3.0 6.0 5.0 -1.336548637946592 8.637667594722788e-05 0.0006159890947550879 GO:0044446 intracellular organelle part cellular_component 30.239470204134932 30.33951642043973 29.84593268385195 29.79050661308412 29.94431622157259 30.523550996376585 29.61149839731391 30.32658426505109 30.371808657562923 29.95869573267353 30.226859534853567 30.398663364261772 30.38915744917509 30.413878894237317 30.844458126622037 30.500032843021245 29.703662742532195 30.203281623157768 30.511855422513552 30.53282826451549 30.094905850979835 30.330371909410523 30.704048253683485 30.60489122592152 30.04989822026023 30.28068182057806 285.0 154.0 218.0 303.0 301.0 252.0 435.0 227.0 404.0 306.0 370.0 193.0 486.0 250.0 320.0 238.0 420.0 374.0 332.0 195.0 385.0 212.0 318.0 266.0 8.0 8.0 8.0 6.0 8.0 8.0 7.0 7.0 8.0 9.0 9.0 8.0 7.0 8.0 7.0 8.0 8.0 9.0 6.0 7.0 7.0 8.0 8.0 8.0 -0.10004621630479704 0.29869755599497017 0.3712893923124729 GO:0044459 plasma membrane part cellular_component 26.8576138964292 27.077285978846888 27.095898285012744 27.208357720152865 27.67383473539572 26.622886103656864 25.98239146976611 27.04251207670581 26.598262599134912 26.752829006576942 26.67261865052832 26.84518587431068 26.710071692919094 27.31792252333072 27.56381636000208 27.58774696404536 26.310116205885844 26.50864480822005 26.715696715118213 27.34641505301477 26.621440937420374 26.897137841915985 26.525894393362798 27.441349130811826 26.901579687619826 26.915458944296645 95.0 119.0 113.0 134.0 91.0 175.0 110.0 135.0 122.0 151.0 136.0 137.0 120.0 171.0 98.0 134.0 159.0 159.0 115.0 144.0 126.0 174.0 154.0 165.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.21967208241768788 0.10596880912720232 0.15148805703407617 GO:0044464 cell part cellular_component 33.52440312749789 33.68389476527153 33.36081847778479 33.118422179900755 33.274113705406826 33.652097734048 33.162301494367625 33.70184604382682 33.557057950358804 33.644045201480196 33.61688888409201 33.816760984197515 33.61481808185728 33.505031525752585 33.800046350043964 33.8290137675997 33.03691906718285 33.70524277054875 33.86848916890617 33.853054798336984 33.63575931096329 33.635319260765506 33.715540584446174 33.862003194602345 33.403494553424125 33.73700098058979 4177.0 3475.0 3535.0 4925.0 4604.0 5430.0 5419.0 5263.0 5591.0 5548.0 5579.0 4160.0 6161.0 5553.0 4302.0 5545.0 6732.0 6380.0 5007.0 4498.0 5503.0 5328.0 5330.0 5767.0 12.0 9.0 9.0 10.0 10.0 11.0 14.0 11.0 11.0 11.0 14.0 9.0 12.0 10.0 10.0 12.0 13.0 12.0 11.0 11.0 12.0 13.0 10.0 11.0 -0.15949163777364106 0.06467168750236378 0.10076188015349562 GO:0044764 multi-organism cellular process biological_process 23.19462578214405 23.201476298773517 22.716194635584745 23.07948481359607 21.76651272136018 19.913283609630216 23.338253720008016 23.24779637223865 22.70548231703476 23.665401040027685 24.397916641840357 24.46586058414805 22.98539852256832 23.893339201224087 NA 20.906710100687352 23.55138897550217 23.009919938024147 24.184945457196914 24.09611081262796 21.060861934517657 18.44808752245729 17.32550380313785 22.354012996873628 23.694110346844987 23.226855833402446 5.0 4.0 4.0 3.0 4.0 8.0 3.0 4.0 5.0 7.0 3.0 4.0 NA 7.0 4.0 7.0 22.0 5.0 4.0 1.0 1.0 7.0 5.0 4.0 3.0 2.0 2.0 1.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 NA 2.0 2.0 2.0 4.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 -0.006850516629466341 0.950924583799356 0.9577970205788449 GO:0044877 protein-containing complex binding molecular_function 22.692844377821018 23.38066386189745 23.18727232489428 23.49206059651797 23.20710004254473 23.07757559039409 22.038035229104647 23.73233918284221 22.899055921288877 22.86146610813702 22.54507183783158 24.043226724348198 22.563218689205733 23.41044383825286 21.90691610333058 22.978537870735067 21.074002466849343 23.769531002627375 23.28885677150323 23.173662196420842 22.853190066667814 23.531971148106532 22.902833641449643 22.743330027637075 22.485470310098314 23.138954771059108 13.0 6.0 12.0 10.0 7.0 12.0 9.0 8.0 12.0 10.0 12.0 10.0 9.0 8.0 7.0 11.0 11.0 13.0 9.0 6.0 10.0 9.0 9.0 13.0 2.0 2.0 2.0 2.0 1.0 3.0 1.0 2.0 2.0 3.0 2.0 3.0 2.0 2.0 1.0 2.0 2.0 2.0 3.0 2.0 1.0 3.0 1.0 2.0 -0.6878194840764316 0.004669131805023211 0.010994483948432015 GO:0045095 keratin filament cellular_component 23.452493502248 22.7707213977116 21.713987297004447 19.294759096949587 25.6329044543645 21.11033319259112 14.963388341601368 21.21630974054849 20.2162728728405 NA 24.713799288524147 24.28584595389091 25.147583777811445 24.760791124055913 21.94793713187627 21.450685653002587 21.120397067566326 22.052312537444454 19.924081974584308 19.647834674937073 22.61790630441768 17.49157826142846 21.29121506796416 23.11971272226004 14.064067860792427 NA 6.0 3.0 26.0 7.0 1.0 6.0 4.0 NA 19.0 19.0 20.0 21.0 8.0 8.0 10.0 14.0 4.0 3.0 7.0 2.0 5.0 9.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.6817721045363996 0.843190481080196 0.8798509367793349 GO:0045109 intermediate filament organization biological_process 20.817074602187176 20.51425986682626 20.387314549386023 19.235849842127674 21.261364997695946 20.954907391604237 18.69596105486389 19.52052979954168 14.85680639687384 13.42742056920834 21.761815949624186 20.814775161060137 21.1011235775836 21.203945832250884 21.767625646262196 21.283539527803907 20.39404333810246 20.30111248421413 19.723918511513787 18.14854154719847 14.054816149077675 NA 21.85076721660984 22.055803415476113 21.201032895763817 18.22327739211902 3.0 4.0 8.0 3.0 1.0 3.0 2.0 1.0 2.0 4.0 3.0 5.0 2.0 4.0 3.0 5.0 5.0 3.0 1.0 NA 3.0 4.0 7.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.30281473536091497 0.4984039238004654 0.5780744395009115 GO:0045150 acetoin catabolic process biological_process 23.811478034013337 25.900966361578714 22.88376471770871 26.03306135937912 26.419444574990173 25.954295430754513 21.455860195799524 24.940590289514308 21.934207118531884 25.38648781140747 20.910480484050375 23.6954893765942 23.6907519385956 25.34494903067568 17.522688248133218 26.22719525890381 17.93678337066629 26.25299408902759 22.34233979573862 26.514093450219768 25.24193559946795 26.087273636560926 18.7300914278306 26.30362693423466 23.378627404691677 26.206707053537738 8.0 13.0 15.0 18.0 4.0 18.0 6.0 14.0 5.0 9.0 9.0 12.0 1.0 19.0 1.0 15.0 6.0 11.0 13.0 18.0 2.0 13.0 7.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.089488327565377 0.0006583371695572323 0.0022696264851033866 GO:0045184 establishment of protein localization biological_process 27.212024264612964 27.749343218359733 27.356857129515987 28.14243201322077 27.329939774779486 26.436484205868613 26.84056180835248 27.39908672794177 26.952653699646802 27.472650839983462 27.329653101915987 27.856361261811017 27.58432796434023 28.09569871018525 27.06413490208652 27.59911630536644 26.575528429752225 26.92491992158677 27.13731410733548 28.4160526124763 26.891791938279447 27.53117478205965 27.34881724668855 27.766107246151233 27.723630823658592 28.236208259439287 186.0 171.0 172.0 155.0 175.0 154.0 171.0 231.0 219.0 241.0 238.0 187.0 198.0 190.0 162.0 199.0 249.0 247.0 182.0 192.0 198.0 203.0 240.0 311.0 3.0 2.0 3.0 1.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.5373189537467695 0.011074437676156606 0.022291771322328135 GO:0045226 extracellular polysaccharide biosynthetic process biological_process 22.008270396810847 22.96903375186397 22.50225258282843 22.722775110527525 23.41333612372455 22.41448218855707 21.050134559226013 22.59114098522217 20.943613084866808 22.380940061696357 22.126246693486646 23.63618302783291 22.838408023408533 23.83848507946891 19.43129097246662 23.166248849394627 20.9790408667988 21.506169570897413 21.565359364115096 23.49436074476233 22.139315673677007 22.75831410744499 21.160630696213865 22.665355255659946 22.069712751194967 22.97416635984489 3.0 4.0 4.0 4.0 3.0 5.0 3.0 3.0 5.0 6.0 5.0 3.0 1.0 5.0 3.0 3.0 4.0 3.0 3.0 3.0 1.0 3.0 4.0 3.0 NA NA NA 1.0 NA NA 1.0 NA 1.0 NA 1.0 NA NA NA NA NA NA NA NA NA NA NA 1.0 NA -0.9607633550531247 0.004669131805023211 0.010994483948432015 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) cellular_component 27.202800573866178 28.246580442346286 27.13493800751997 27.465937546917356 26.545227354365306 28.060804020191732 26.910878875051583 28.28912306024732 26.88357372023745 28.24708715358023 27.362991389243504 28.357344277337145 27.252324704086273 27.629933562140344 26.769432336530446 28.678913930171905 27.010374819473988 28.650392768977657 27.87179444616664 28.15518504176003 27.76765571680809 28.155385554240368 27.146702751419376 28.471910917598013 27.194997495390982 28.327422652408792 89.0 59.0 56.0 87.0 79.0 100.0 90.0 106.0 97.0 120.0 87.0 59.0 90.0 90.0 76.0 112.0 114.0 114.0 107.0 97.0 93.0 95.0 93.0 124.0 NA NA NA NA NA 1.0 NA 1.0 NA 1.0 NA NA NA NA NA 1.0 NA 1.0 NA 1.0 NA NA NA 1.0 -1.043779868480108 8.637667594722788e-05 0.0006159890947550879 GO:0045454 cell redox homeostasis biological_process 26.311129478612102 26.73137554483064 25.645172447585395 26.289857452963037 25.283887541837373 26.39004640882168 26.640088876085702 27.422628417298693 25.529416028516827 26.811307570997286 26.56439489047954 25.987082920677924 26.34767645385057 26.98058879702234 25.419644163846048 26.95991623894743 25.693432703208128 26.77671253408159 27.619095798317343 26.704090139105396 26.11080303801825 26.168919584683515 26.576800155630302 27.2565604091956 26.428161260406824 26.24950666590255 56.0 65.0 41.0 74.0 54.0 102.0 59.0 89.0 62.0 81.0 64.0 72.0 72.0 95.0 56.0 92.0 81.0 104.0 48.0 72.0 61.0 100.0 57.0 78.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.42024606621853877 0.043308142810791976 0.0706517153305469 GO:0045727 positive regulation of translation biological_process 21.911292234761834 22.51715488954349 22.316727322852177 21.836300686683693 20.80012263499185 22.646347246397585 21.11354446055671 22.61284825180973 22.745024688133288 22.30428261866852 22.679559788553075 22.503038463525368 21.985608433244167 22.477215153747807 21.219753686746568 22.554672944444622 21.510368700173807 22.423391513358112 21.49810363950518 22.461846831634325 21.184718724053376 21.79775317251947 21.83598375324944 23.337232934420786 22.415115256825253 22.6408295134818 9.0 12.0 6.0 13.0 9.0 21.0 15.0 20.0 15.0 16.0 10.0 13.0 9.0 25.0 10.0 23.0 11.0 17.0 9.0 11.0 12.0 23.0 15.0 19.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.6058626547816566 0.017926339076638688 0.03379466943753034 GO:0045892 negative regulation of transcription, DNA-templated biological_process 22.126828401919322 22.178021155559467 21.30030518237217 21.96677517765173 23.211818180238577 21.464966997040502 22.10470901586865 21.403375515281333 20.7204819664222 23.20906481771488 22.255553385147227 21.473772622682727 22.460488420134002 21.856583732267328 21.433366644229807 20.233594686557442 20.336662033180712 21.07809661598035 20.5406265387826 23.721564622589497 23.338414878910786 21.58260389785375 21.767157801055298 21.369740993096602 22.464083345139912 22.86485154464377 10.0 12.0 13.0 7.0 11.0 13.0 9.0 17.0 11.0 9.0 16.0 9.0 7.0 8.0 4.0 11.0 8.0 22.0 16.0 12.0 8.0 10.0 15.0 20.0 NA NA NA 1.0 NA NA NA NA NA NA NA NA NA NA NA 1.0 NA 1.0 NA 1.0 NA NA NA NA -0.05119275364014442 0.9080725552559752 0.9266349541778063 GO:0045934 negative regulation of nucleobase-containing compound metabolic process biological_process 22.58996419040503 22.2264498133991 21.41214146249033 21.96677517765173 23.211818180238577 21.464966997040502 22.496951917972762 21.403375515281333 22.146841310398358 23.24600071451929 22.736324227442196 21.635569120604124 22.900423657589695 22.03531572771797 22.376299452152203 20.233594686557442 21.352293071238762 21.07809661598035 22.125566073084396 23.730777335980626 23.42759588328258 21.58260389785375 22.336707669355462 21.369740993096602 23.035544801111804 23.00123485684784 11.0 12.0 13.0 7.0 14.0 13.0 22.0 18.0 18.0 10.0 23.0 10.0 15.0 8.0 9.0 11.0 16.0 23.0 17.0 12.0 19.0 10.0 28.0 22.0 2.0 1.0 1.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 3.0 0.3635143770059308 0.10596880912720232 0.15148805703407617 GO:0046026 precorrin-4 C11-methyltransferase activity molecular_function 20.665875814651194 20.57999361815186 18.40863414677072 NA NA NA 19.714622694354226 20.281692291354908 21.34110532091145 21.72466675846755 18.427951620792662 20.681330194722825 21.539337200729804 19.831230213009764 20.869718960555407 NA 20.666850430728715 20.933317286274303 22.024625380029946 19.13425018702842 18.944174521426238 17.86806716771494 19.922612885596045 18.810169751643894 20.687506876673414 21.728912198372818 2.0 NA NA NA 3.0 3.0 5.0 5.0 2.0 3.0 5.0 3.0 6.0 NA 3.0 5.0 7.0 2.0 2.0 1.0 5.0 2.0 6.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.08588219649933393 0.9092690452142217 0.9270978500223437 GO:0046031 ADP metabolic process biological_process 28.36453208597173 29.538736051415896 29.03292523803698 28.88319281062353 28.64851955054902 29.64693607295549 27.70564036382776 29.76769514597598 27.15037735014427 29.371779983024112 28.20138105499236 29.303920419480924 28.00271315890037 28.84014311112464 29.215168893951525 29.95019581357689 27.783663941510447 30.149569400845838 29.16270559016053 29.75627546528489 28.162150263730013 29.462312242059394 27.589292681683173 29.49380388153409 28.030533899674296 29.25409120217012 99.0 94.0 119.0 136.0 101.0 163.0 117.0 136.0 119.0 131.0 102.0 88.0 154.0 130.0 105.0 138.0 181.0 143.0 131.0 127.0 117.0 117.0 103.0 129.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 1.0 1.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 -1.174203965444164 0.0001386794054294884 0.0007006959432226783 GO:0046034 ATP metabolic process biological_process 29.67565454983332 30.79738894530341 30.20172495033256 30.11780027381743 29.82013015777596 30.85712424654016 29.082174452687394 30.99882479300793 28.710590864704752 30.65477950923988 29.56896865976163 30.6246907195717 29.42231289111581 30.12979789704701 30.360879360359448 31.22137642552505 29.160100422670908 31.376085223037766 30.454702104053375 30.97299686608082 29.648294915658788 30.71080726699649 29.109396232779712 30.78224914706519 29.410217464155874 30.588227567638803 300.0 280.0 335.0 395.0 303.0 458.0 358.0 406.0 354.0 391.0 322.0 272.0 433.0 387.0 297.0 404.0 498.0 438.0 386.0 377.0 353.0 335.0 323.0 401.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.1217343954700887 0.0001386794054294884 0.0007006959432226783 GO:0046112 nucleobase biosynthetic process biological_process 26.98490495326488 27.11605609124361 26.904358117230657 26.33235864095478 25.38444486875072 26.905253292022376 26.512714833658773 26.895195412212487 26.670480908493147 27.424397700090328 27.574292161798173 27.92962255563405 27.63875007539865 27.142405073331226 26.67352635976737 26.882788912150442 26.620394469309765 26.674525749693608 27.078122942598572 27.125548490888114 27.35569101617157 27.007265074505728 27.40223241709976 27.49311947910836 26.739647041659843 26.903533932320066 59.0 61.0 32.0 59.0 74.0 91.0 100.0 100.0 78.0 96.0 89.0 75.0 105.0 80.0 83.0 93.0 99.0 102.0 74.0 74.0 84.0 77.0 88.0 87.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.1311511379787298 0.4189234409463829 0.5022252202700153 GO:0046128 purine ribonucleoside metabolic process biological_process 26.78496657929375 27.869261114317368 27.091691859726136 27.853406397966065 27.36131506041671 27.846162486574002 26.07895553677752 27.878565363076266 26.01415709549436 27.54118614112761 26.40238027809762 27.575422067286 27.311750427915825 27.959571529114882 26.372937483319483 27.869421729140072 26.29570071326348 27.707236103890505 26.49480736280787 28.354629319059445 27.2986551830581 27.632791925180094 27.039074553263568 27.971377010228014 26.73072012219481 28.042293219057 128.0 111.0 155.0 196.0 98.0 202.0 140.0 199.0 130.0 179.0 177.0 142.0 132.0 199.0 103.0 204.0 175.0 164.0 186.0 173.0 156.0 168.0 135.0 219.0 5.0 2.0 2.0 2.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 -1.0842945350236164 3.225641456243767e-05 0.0005099643033035255 GO:0046129 purine ribonucleoside biosynthetic process biological_process 25.36693661828302 26.600858150930552 25.83409106910625 26.65720259090233 25.934321312664274 26.636033124900603 24.64865232082738 26.604366692951608 24.53109869248807 26.293285301702447 24.98731233093465 26.259842147111375 25.93611843394464 26.725914917825733 25.034535073382568 26.61055927346141 24.806744028301647 26.332585794180602 25.14835636587625 27.032488332531987 25.871687056827213 26.38734064193985 25.45099727995473 26.86116870880139 25.22241123831936 26.59946556554853 47.0 51.0 55.0 71.0 38.0 74.0 49.0 75.0 46.0 68.0 61.0 54.0 53.0 71.0 38.0 74.0 67.0 66.0 67.0 67.0 52.0 64.0 44.0 81.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.233921532647532 3.225641456243767e-05 0.0005099643033035255 GO:0046144 D-alanine family amino acid metabolic process biological_process 20.30916389943202 20.285763146036984 20.202299444738028 18.39079850763817 19.57856069100217 19.62667408657724 20.955548692862955 17.834663721407317 20.67662208401689 21.323115913417016 21.428979015907853 21.74195022703785 20.77097037805543 18.619836130762287 18.538105822408834 19.46329643919817 20.769653455599773 17.70108290610442 19.10834268670508 20.45446928911084 18.899298398866197 19.44312480447125 18.73156186889231 20.518259577422565 20.628265619116693 21.43296281856506 6.0 2.0 2.0 2.0 4.0 2.0 8.0 6.0 10.0 8.0 6.0 6.0 2.0 6.0 8.0 2.0 4.0 8.0 2.0 4.0 2.0 4.0 4.0 8.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.023400753395034002 0.5253727863737021 0.6008633207515945 GO:0046148 pigment biosynthetic process biological_process 23.88784974895081 25.31657160814845 24.643700802462874 25.337920507546702 24.101387847640748 26.040872780741363 23.512862748157787 24.98178860581995 22.811282252637373 25.213322063884092 24.12898394257372 24.901530747756954 24.733551781111625 25.34181505671081 23.57342807935661 25.661230312201265 23.27410408769321 24.81557274490541 22.79134215108408 25.560214958568306 23.46600086031754 25.334561475983303 23.784594431379727 25.625324681103873 24.293624322554003 24.098556881624674 14.0 27.0 13.0 22.0 15.0 31.0 17.0 31.0 16.0 27.0 28.0 26.0 18.0 34.0 15.0 29.0 22.0 37.0 16.0 27.0 17.0 21.0 23.0 27.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 -1.4287218591976405 0.00010962068302139599 0.000648372570666835 GO:0046164 alcohol catabolic process biological_process 26.29620842721467 26.33114663417459 23.74495809836153 26.104353637852892 26.458808179087445 26.00069182480473 25.77020201287273 25.098746845464053 25.77721489570923 25.76192524842508 26.151509475169053 25.802065197527288 26.51561984887269 25.43894455198441 24.87537133739743 26.247798862695703 23.92617473373189 26.319475624538345 28.382470850145626 28.019161603997674 27.05384735214525 26.12398886603405 24.798181792598104 26.320251923603703 24.94060165904521 26.334242763814768 17.0 19.0 22.0 24.0 39.0 25.0 38.0 18.0 43.0 39.0 46.0 20.0 28.0 22.0 24.0 21.0 79.0 49.0 47.0 22.0 33.0 15.0 35.0 20.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 -0.03493820695992156 0.4189234409463829 0.5022252202700153 GO:0046174 polyol catabolic process biological_process 25.58713305309967 22.83002733501344 22.59136073245956 21.729977553507663 21.181693742133007 21.018945917549267 24.929131299441966 21.831049805512684 25.340332103976326 22.124881568731904 25.69039250219705 25.377691412202516 26.225978679863143 21.45217140596167 24.866517565592197 20.107783460703683 23.216657835735703 21.846693644609527 27.77951918565388 23.764025119581323 26.16589256512401 20.809426237328427 24.54219552594619 19.87267826672729 24.15501869318345 22.771151433605233 9.0 6.0 6.0 6.0 30.0 7.0 28.0 3.0 34.0 29.0 35.0 8.0 27.0 3.0 20.0 6.0 58.0 29.0 33.0 4.0 28.0 2.0 25.0 11.0 2.0 1.0 1.0 1.0 4.0 2.0 3.0 2.0 4.0 3.0 3.0 2.0 2.0 2.0 4.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 2.7571057180862297 0.0018227351663913985 0.005134928866041682 GO:0046349 amino sugar biosynthetic process biological_process 21.04367519511398 22.044974943178865 21.970340039405393 20.808168064120814 20.542751502232 22.158041803317534 20.749896488067282 22.083898469326204 13.87309519278063 22.49219814603734 21.015820802736712 21.540195821494613 21.64320689240708 22.335793133677207 20.094765652106503 21.3269989729572 17.51276864171228 21.21878910436645 22.531888672520342 22.73674633534253 21.466521931873764 21.903903831539864 20.32089539692104 22.37871118353426 20.564145351538826 22.332978324242802 4.0 6.0 5.0 9.0 5.0 11.0 1.0 10.0 4.0 9.0 6.0 9.0 7.0 7.0 1.0 10.0 12.0 13.0 7.0 8.0 4.0 16.0 5.0 10.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.0012997480648842 0.005583616806378765 0.012692811975156102 GO:0046352 disaccharide catabolic process biological_process 24.03650549048101 24.935860584890772 25.38430426758183 25.028760678966545 25.20121049625985 25.339841145760694 23.70810815339182 25.74233100782435 19.801872474524533 24.2284105047751 21.845277445313076 24.99793250897741 23.81125221566125 24.942681877374266 25.340865265459872 25.85074617864151 22.58831015018093 24.167807025416703 24.917613798187407 23.93181444697665 22.466417058365913 24.88000408118951 20.519048760613693 24.15352505257185 21.61621718297809 24.391353879298787 49.0 37.0 46.0 27.0 19.0 44.0 3.0 35.0 14.0 40.0 21.0 27.0 38.0 61.0 17.0 35.0 36.0 31.0 17.0 32.0 6.0 30.0 14.0 34.0 2.0 2.0 2.0 1.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 1.0 2.0 1.0 1.0 1.0 2.0 2.0 1.0 1.0 1.0 1.0 2.0 -0.8993550944097635 0.03266344168491133 0.055917661485280296 GO:0046364 monosaccharide biosynthetic process biological_process 27.55456422925397 27.92928241525012 27.841196563230557 27.08320887271524 27.417701758136424 27.49379923248075 27.386433958386732 28.13004934662629 26.83819840964941 28.08538960998657 27.437731622158733 28.652438170590795 27.372608620889697 27.48833634303446 27.413912963758374 28.222831320248154 27.039663228987152 28.000794806324624 28.18895123128253 28.064099461838797 28.37088686252295 28.165127922906102 27.328612825049238 27.357304615841045 27.220325689052572 27.657886955872968 64.0 23.0 50.0 37.0 106.0 88.0 117.0 102.0 113.0 102.0 119.0 54.0 119.0 71.0 95.0 77.0 182.0 122.0 110.0 58.0 130.0 71.0 113.0 106.0 2.0 1.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.3747181859961515 0.04964722965745621 0.07872902492059129 GO:0046365 monosaccharide catabolic process biological_process 23.91624301491889 23.9912878450076 24.665477173073594 23.48249941253105 24.43658010447093 24.80976107263407 23.876466498938772 24.289530673526677 22.391993193608517 22.604694238105626 23.67090482399597 24.038354015140648 23.880615001321683 23.010729949412045 24.52230444289976 24.937115424199252 23.609308249517056 22.627691495463985 25.214978251901737 23.97383042422732 22.165561095052112 23.966961269322486 22.321851651401357 24.458097581157627 22.300109223191466 23.50403685439849 29.0 15.0 28.0 18.0 22.0 21.0 11.0 21.0 20.0 21.0 28.0 10.0 41.0 35.0 27.0 13.0 38.0 27.0 16.0 23.0 12.0 25.0 13.0 24.0 2.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 1.0 1.0 3.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 -0.07504483008871077 0.5253727863737021 0.6008633207515945 GO:0046374 teichoic acid metabolic process biological_process 22.655049865746516 25.703929551979126 24.79887273102695 25.61866661091291 23.80107957713856 25.945647029960714 20.960203096262322 26.39090240376029 19.843086778671857 25.364645200372163 19.710792982022745 24.92836490308729 22.305225545433718 25.988960032780447 22.81857390421575 25.914965419829677 20.883591659742017 25.27305950694727 22.31693058378272 25.983124408307336 22.37472962312862 25.40353334660577 17.369519027760624 25.505069767851246 22.579074364097252 25.51282963885827 38.0 50.0 20.0 40.0 8.0 68.0 4.0 41.0 5.0 37.0 9.0 51.0 20.0 56.0 5.0 49.0 15.0 48.0 11.0 45.0 2.0 56.0 12.0 48.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 -3.0488796862326097 3.225641456243767e-05 0.0005099643033035255 GO:0046386 deoxyribose phosphate catabolic process biological_process 22.938283645914588 22.283481617215475 20.487095846191238 20.944295955496823 23.52563715784553 22.178467840144453 19.599168337752324 24.021052511631684 20.734445067468688 22.523661678398966 20.090689474472555 21.447070742263726 20.178629204380268 22.58408684428257 20.068363679345232 21.374406790487427 NA 19.91141303979488 25.874316312685732 22.93495344244184 22.63791682516573 22.478620472769386 18.068329009089148 21.010683924593906 19.22257335252731 21.3183631250384 2.0 4.0 5.0 5.0 6.0 11.0 3.0 6.0 3.0 7.0 5.0 8.0 2.0 1.0 NA 3.0 15.0 11.0 8.0 6.0 1.0 3.0 2.0 6.0 NA NA NA NA 2.0 NA 1.0 NA NA NA NA NA 1.0 NA NA NA NA NA NA NA NA NA NA NA 0.6548020286991125 0.08483774479657043 0.12710384814660253 GO:0046390 ribose phosphate biosynthetic process biological_process 29.80110304641831 30.55182971092142 29.875567193833838 29.890337673953727 29.53990889297833 30.44853881018853 29.45922951304388 30.734308654080305 29.416886457107054 30.46931088236493 29.99545724452093 30.46787383900596 29.967901650998105 30.126778316795715 30.115183474335407 30.933959751348173 29.383029583851023 30.96482035152137 30.330787976410214 30.68953141725914 29.853696757639607 30.42524366587533 29.533780726889443 30.669448668976425 29.78281158647409 30.4526320144268 488.0 488.0 469.0 584.0 541.0 785.0 597.0 733.0 614.0 728.0 668.0 553.0 670.0 740.0 547.0 762.0 816.0 812.0 624.0 625.0 630.0 679.0 656.0 753.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.7507266645031123 0.00010962068302139599 0.000648372570666835 GO:0046394 carboxylic acid biosynthetic process biological_process 29.668547575498515 30.717374653201837 29.838783160391078 29.82503519508727 29.507734228314103 30.545570313959022 29.19541739907619 30.70380687048473 28.882288152301825 30.55651812996568 29.632928914538255 30.84359301416812 29.688649213319692 30.31242587320297 30.27945245719598 31.170444546742612 29.20020441355535 31.359393751303354 30.646254258108424 30.727276826583534 29.418192102065078 30.347148061035966 29.323674661078282 31.069097844393397 29.422045104419713 30.492398122393595 552.0 676.0 616.0 872.0 504.0 1115.0 520.0 1098.0 653.0 1121.0 755.0 862.0 734.0 1200.0 525.0 1317.0 915.0 1011.0 715.0 926.0 744.0 1170.0 647.0 1082.0 5.0 4.0 4.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 -1.0488270777033222 0.00021985068263840352 0.0009941074345388681 GO:0046395 carboxylic acid catabolic process biological_process 29.30552578322073 27.084919593473266 28.527786648316013 26.738236971878052 28.437326452667303 26.855624865486067 29.04416843410503 27.36719697987161 29.574504192815386 26.484352177452244 29.71250377574959 27.666536429562235 29.38778140261207 26.299437822887985 29.602244594062995 25.841021695529147 28.81808592923561 25.811917096646265 29.62172749506333 28.792915227580057 27.865060439009838 27.674395529835486 30.041649877594644 23.29123208724112 29.597396223383473 26.62765117330845 85.0 59.0 161.0 113.0 181.0 107.0 256.0 78.0 280.0 94.0 246.0 69.0 257.0 64.0 165.0 49.0 310.0 219.0 179.0 79.0 231.0 24.0 224.0 88.0 3.0 3.0 2.0 3.0 4.0 2.0 4.0 3.0 4.0 3.0 4.0 4.0 3.0 3.0 3.0 3.0 4.0 4.0 4.0 3.0 5.0 3.0 4.0 3.0 2.220606189747464 6.784570247173055e-05 0.0005498145239267514 GO:0046405 glycerol dehydratase activity molecular_function 22.00722603744544 21.00259710125148 21.77877269594773 16.887050546611714 NA 18.182477530058282 21.577198389384538 22.23147404094544 20.069677314352823 23.014810374560188 20.575176978616273 21.272746268462072 21.989373800258694 17.93241034250571 21.019910332959107 16.102588529267212 22.54737852076889 21.08833981855437 NA NA 23.419370477610855 19.943757632632295 NA NA 22.227520132090813 20.06780933318557 5.0 1.0 NA 2.0 4.0 9.0 6.0 6.0 1.0 7.0 5.0 1.0 6.0 1.0 6.0 3.0 NA NA 13.0 2.0 NA NA 3.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.00462893619396 0.05004352124870507 0.07925674431266996 GO:0046416 D-amino acid metabolic process biological_process 21.195828596090028 20.639311231211824 20.202299444738028 20.12686757262629 19.885716405146862 19.62667408657724 22.453311395555712 18.371579052685245 20.942964737053607 21.36270309151876 21.891694500943718 21.74195022703785 21.161560384114303 20.750658541151207 20.563880486243125 19.72761858000988 21.567197970460327 19.754678400969752 21.434600191177925 20.824469791832648 18.899298398866197 20.142147284234614 20.197056692511584 20.64252145958686 21.727116086340537 21.48413797720529 6.0 4.0 3.0 2.0 9.0 3.0 11.0 7.0 14.0 8.0 7.0 9.0 5.0 7.0 12.0 3.0 12.0 9.0 2.0 6.0 3.0 5.0 9.0 9.0 2.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 3.0 0.5565173648782036 0.14891467317876572 0.20512749682902828 GO:0046434 organophosphate catabolic process biological_process 28.573557557843447 29.711480913709906 29.211373945183833 29.12096523072348 29.0992457789646 29.792102976297365 27.900182251948113 30.029066964886226 27.300339821367054 29.553719461431275 28.246830944232315 29.456217990202198 28.133498382163683 29.08487402584004 29.362625100693137 30.104046100470228 27.862041726283234 30.246670107586965 29.513097620335675 29.948633380660766 28.38564647099829 29.60876711129775 27.66865651120093 29.638689572354828 28.178934867755107 29.438542293825122 162.0 167.0 200.0 216.0 159.0 279.0 144.0 227.0 149.0 212.0 142.0 158.0 211.0 211.0 136.0 231.0 283.0 245.0 189.0 209.0 142.0 194.0 143.0 211.0 4.0 4.0 3.0 4.0 5.0 4.0 3.0 4.0 5.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 5.0 4.0 3.0 4.0 3.0 4.0 4.0 3.0 -1.1379233558664588 0.0002755038114342687 0.0011655212090507369 GO:0046451 diaminopimelate metabolic process biological_process 25.13505019347885 26.194120499618613 24.722301878271885 25.362349995218764 24.249987577036578 25.360667104252904 25.17035946190689 26.462649024513503 23.533653356654266 26.25932403675859 25.60172634788382 26.31604722612997 25.87167773682421 26.357693280984048 25.72001035373338 26.20983899321636 24.62260995494252 26.81003890803964 25.3064379418456 26.066324902719703 25.07218786896625 25.27857252535532 25.37408296195923 26.429292868124538 24.88363884545432 26.518371002406997 52.0 59.0 41.0 61.0 43.0 107.0 25.0 97.0 40.0 107.0 68.0 85.0 40.0 95.0 44.0 95.0 78.0 87.0 73.0 78.0 56.0 90.0 51.0 90.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.0590703061397626 0.0006583371695572323 0.0022696264851033866 GO:0046474 glycerophospholipid biosynthetic process biological_process 21.045760207248907 18.754662385070983 19.434514480908227 19.139719342890817 17.775971721829173 16.62259667134557 21.064649534310448 NA 17.385059794716096 18.56206766840408 21.198008751989885 18.548844970097566 23.04152552089169 19.65333390118186 18.21464523215143 15.33770334296553 16.335935796717 20.14108926145804 21.840682410423927 19.483178570427032 20.994686919353143 14.318712894189645 21.59314412454918 16.691072809102014 21.09790687082117 19.02877214641114 2.0 2.0 1.0 1.0 7.0 NA 2.0 3.0 7.0 4.0 9.0 5.0 3.0 1.0 1.0 9.0 18.0 5.0 5.0 1.0 7.0 2.0 9.0 4.0 1.0 2.0 1.0 1.0 2.0 NA 2.0 2.0 2.0 3.0 2.0 2.0 2.0 1.0 1.0 1.0 3.0 2.0 2.0 1.0 2.0 1.0 3.0 2.0 2.2910978221779246 0.042254020654422304 0.06966052546462224 GO:0046483 heterocycle metabolic process biological_process 35.49887583330142 36.27169667088151 35.651987888284026 35.6545987784702 35.311737744036606 36.212934133905456 35.12466367178237 36.44046898049885 35.05062515858946 36.18501927382498 35.662989640408256 36.174442496734855 35.62562720205132 35.83296962298789 35.891797515915755 36.629678845973146 35.04157695431618 36.68986182868852 36.053199200401615 36.45374559858296 35.468296232744564 36.140874892430574 35.242059230430705 36.3737016449676 35.45058703544354 36.13661320932035 24322.0 24575.0 23881.0 29844.0 27083.0 38783.0 30446.0 35979.0 31458.0 36220.0 34026.0 27883.0 33713.0 36506.0 26693.0 37335.0 41996.0 40161.0 30976.0 30776.0 32152.0 34166.0 32716.0 36676.0 13.0 12.0 11.0 13.0 13.0 12.0 14.0 12.0 13.0 14.0 14.0 14.0 14.0 12.0 14.0 12.0 13.0 12.0 12.0 11.0 13.0 14.0 13.0 14.0 -0.7728208375800918 0.00010962068302139599 0.000648372570666835 GO:0046486 glycerolipid metabolic process biological_process 22.893194094165413 22.820212629262425 22.759230473010806 22.490336597564806 20.785544919174928 22.446917235105577 22.78590485997297 23.10332437317017 18.97002229543725 22.32405878426437 22.90790857477573 22.73477243473755 24.668450006147484 23.416705077027736 21.263826703357587 22.74611305986477 20.896027037022904 23.424695365136532 23.708632027088427 22.519299095393446 22.70046578030295 20.564905334657105 23.190666188997398 23.68041108864094 22.881127265120753 22.395887971679592 12.0 14.0 10.0 11.0 25.0 8.0 6.0 16.0 24.0 22.0 30.0 26.0 14.0 16.0 11.0 50.0 64.0 24.0 18.0 8.0 22.0 18.0 31.0 17.0 2.0 2.0 3.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 0.07298146490298763 0.9080725552559752 0.9266349541778063 GO:0046496 nicotinamide nucleotide metabolic process biological_process 28.54084784889725 29.67618994153964 29.13483237691803 29.09204432523941 28.845924767457017 29.762949676948185 27.921387672857428 29.91655335641245 27.39554559480052 29.512883346290174 28.376854044597586 29.45923046305677 28.24239136434138 29.10598373715765 29.31443684958269 30.034090601032766 27.958226109988352 30.19862558966332 29.373519650432957 29.90203099263468 28.356528867921266 29.589736727229372 27.791271093240404 29.64809539974915 28.242767887700147 29.446576043017405 138.0 154.0 164.0 172.0 153.0 238.0 164.0 209.0 166.0 201.0 169.0 167.0 219.0 191.0 143.0 189.0 273.0 224.0 183.0 183.0 171.0 194.0 164.0 179.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.1353420926423894 0.0001386794054294884 0.0007006959432226783 GO:0046527 glucosyltransferase activity molecular_function 22.397217652741364 22.35583360559669 23.465175472493105 21.319633120996734 22.84827551688577 21.143861668156266 21.627790577684106 22.41446288911021 21.071903733078734 22.291904753714615 22.349993436423688 22.327855583601426 22.939269130325044 21.662867219163104 23.14460703943945 23.720805474568127 21.331099529187693 22.865914039998344 21.007950797565208 21.12747063970373 22.334144469962396 22.77088389959848 20.652172855983093 22.221785866886176 22.81219982917745 22.055288889577326 9.0 10.0 8.0 8.0 11.0 8.0 6.0 9.0 13.0 9.0 16.0 7.0 16.0 23.0 13.0 22.0 13.0 6.0 8.0 11.0 6.0 14.0 20.0 7.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.041384047144674696 0.8624902301359216 0.8917877441670506 GO:0046537 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity molecular_function 21.97387248547237 20.561769445351 21.15783400195186 NA 23.43219320523077 22.521547255331765 NA 18.66506733665293 NA 17.663264047191912 17.9070584112398 19.653055538042807 20.084883620119022 NA 19.878220559082976 19.858190873588054 18.38518714148887 20.300263391602808 23.796320028534552 20.32227935098549 21.26078298675944 18.51510274784342 22.81508576074307 21.75385950030469 18.637341914870888 19.05732672419175 7.0 NA 7.0 9.0 NA 4.0 NA 2.0 1.0 3.0 5.0 NA 3.0 2.0 2.0 3.0 10.0 2.0 4.0 2.0 12.0 4.0 2.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.4121030401213694 0.3643461266335529 0.44318125344900006 GO:0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity molecular_function 26.65385150589589 27.77676070586663 27.665810529626498 27.181149986174933 27.47437294740471 27.62447568178101 26.380015643175373 27.999514831381717 25.809000925744765 27.594789412052712 26.219879178544282 28.27502864821487 26.30200500873406 27.25058548632133 26.53234344728499 28.17609180861463 25.990907721708933 28.05436887659501 26.360464509324927 27.896086484243718 27.403138754400764 28.201822558534086 26.007162027054896 26.923327818280807 25.97142344877977 27.399019320207792 29.0 20.0 33.0 40.0 31.0 25.0 41.0 26.0 35.0 33.0 33.0 20.0 45.0 33.0 27.0 29.0 37.0 31.0 42.0 36.0 32.0 30.0 28.0 36.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1229091999707386 0.0008121171348941295 0.002709952364566507 GO:0046653 tetrahydrofolate metabolic process biological_process 26.763853401409172 25.35481647684897 25.378351837533874 25.23736992126119 25.321157099098365 24.134309556297367 26.397357020083266 25.00016467512981 26.697963427457122 25.19869589869964 27.240525248576656 25.772844414923945 26.314168841934585 25.54970074292181 27.40350370956389 25.114585419671144 26.480489939628054 24.678775430148143 27.97061277316269 26.578872116182453 25.421522620401 24.9675211638979 27.1020325509043 24.9333456178702 26.831847891399608 25.580196326554645 39.0 36.0 36.0 42.0 54.0 56.0 53.0 58.0 60.0 53.0 60.0 38.0 75.0 49.0 42.0 42.0 65.0 71.0 60.0 39.0 49.0 42.0 61.0 55.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 3.0 2.0 1.0 3.0 2.0 3.0 2.0 1.4090369245602012 0.0009986863791802587 0.0031633517797384847 GO:0046656 folic acid biosynthetic process biological_process 24.152481578336328 20.97109718658761 19.421167125471907 20.256506799352533 16.382100037946756 20.41303021222847 16.5466996517334 20.717071882357267 18.454880164736768 20.457791615242048 19.645587886384128 21.453151065206068 20.884113833940862 21.80015231730599 26.042044648221975 19.799825794794106 16.420322611209258 19.6708365040786 27.154526517336418 20.244971518419487 17.196368815893905 NA 19.250217293358396 22.080589695722466 18.699533102663207 21.442736360751802 4.0 3.0 1.0 3.0 2.0 8.0 3.0 5.0 3.0 6.0 2.0 5.0 4.0 6.0 1.0 4.0 8.0 8.0 3.0 NA 5.0 10.0 4.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 3.1813843917487183 0.022774727854040278 0.04131229703756143 GO:0046700 heterocycle catabolic process biological_process 29.29036484229377 29.782473139467893 29.421578413076038 29.19663500348531 29.29462640632681 29.872840405515948 28.81001546876009 30.05663859255481 28.93899559699048 29.590801081983994 29.363928278611365 29.57382308987039 29.177060485688585 29.146913482361107 29.894060257110553 30.10264773422155 28.65669538630605 30.259224837291928 29.79791352283977 30.19256394232709 28.685861265950518 29.67680822984305 29.5136917539534 29.6992371862635 29.30972599341131 29.518864773232625 217.0 201.0 248.0 301.0 262.0 341.0 322.0 295.0 323.0 299.0 299.0 224.0 357.0 276.0 229.0 292.0 434.0 383.0 286.0 239.0 320.0 256.0 289.0 280.0 5.0 3.0 5.0 4.0 7.0 5.0 7.0 5.0 5.0 4.0 6.0 5.0 6.0 3.0 4.0 4.0 6.0 5.0 7.0 4.0 5.0 4.0 5.0 4.0 -0.4921082971741235 0.007911788680711459 0.016907384030013527 GO:0046872 metal ion binding molecular_function 30.902335232724862 31.057977530675718 30.486945467670946 30.349344563461088 30.55800115657503 30.75453020717911 30.764002319979404 31.118438748137198 30.969170164801035 31.07543555662461 31.081777819619607 31.20597738590095 31.135653616820232 30.970824355952555 31.273613245698012 31.250513884954195 30.56204820190391 31.11534604817246 31.08635231564045 31.236787675269536 30.67454168865081 30.80334117321785 31.01562260777451 31.261522595194354 30.963751724620327 31.28250233574881 1146.0 1077.0 1112.0 1334.0 1355.0 1678.0 1496.0 1725.0 1627.0 1759.0 1730.0 1329.0 1698.0 1723.0 1223.0 1778.0 2099.0 1983.0 1418.0 1440.0 1606.0 1656.0 1644.0 1796.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.15564229795085538 0.10596880912720232 0.15148805703407617 GO:0046873 metal ion transmembrane transporter activity molecular_function 22.928418212131845 23.469704691201592 22.07969384142355 22.858701924906487 20.499470568599648 22.800003505715235 22.80648432405876 23.03913549134568 22.933246409530202 23.427997892585587 22.56456589038993 23.952491830572022 23.802917337222944 22.793587999365982 23.39638613813901 23.874891709975003 23.72401737944435 23.311407260392794 21.7688562622622 23.26231916346477 23.071300201289848 23.08088309582385 23.392229007289767 23.64617820968956 22.364288129066587 24.469372996061047 13.0 23.0 9.0 28.0 11.0 30.0 24.0 40.0 20.0 45.0 23.0 24.0 20.0 46.0 21.0 35.0 14.0 32.0 18.0 32.0 21.0 39.0 20.0 36.0 4.0 3.0 2.0 4.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 3.0 4.0 4.0 3.0 4.0 2.0 3.0 3.0 4.0 1.0 3.0 3.0 3.0 -0.5412864790697469 0.0734883472918226 0.11239394291690516 GO:0046890 regulation of lipid biosynthetic process biological_process 19.86281997630739 22.242009396741015 17.626504117462254 21.70048912666737 15.387498233203914 22.038066902572755 20.36552165192713 22.21197536522675 19.708586819272174 22.428791261908913 20.49485955229591 22.724549961029872 15.47420556183059 20.575634498777784 NA 21.918579820885924 20.96403119741996 23.77526375921727 18.85744197489092 22.581298922278037 NA 20.184912995997912 20.19768541986015 22.64060204939921 20.807752626678678 18.886685702334713 3.0 6.0 3.0 3.0 4.0 6.0 3.0 3.0 3.0 6.0 3.0 6.0 NA 3.0 4.0 6.0 5.0 4.0 NA 3.0 6.0 6.0 4.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 4.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 -2.379189420433626 0.001941172060729515 0.00545626741394242 GO:0046903 secretion biological_process 24.120891870015782 22.16588240252341 19.893806171860504 NA NA NA 23.157108803678412 20.656279897260607 21.968714228356177 22.814371199799968 24.667820942532373 23.173742582853517 25.445921507203998 21.886129142698607 21.01813662418511 18.34767063022005 24.502100048265167 19.03553847242165 21.2949302141463 22.16807121680705 24.588322028097235 NA 25.108657767695995 18.944949166710355 24.518086868722754 23.727938753450136 4.0 NA NA NA 10.0 3.0 8.0 5.0 18.0 8.0 16.0 2.0 8.0 2.0 14.0 3.0 2.0 3.0 28.0 NA 23.0 3.0 24.0 20.0 2.0 NA NA NA 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 NA 3.0 3.0 2.0 2.0 1.9550094674923741 0.03668277440246522 0.062285853679287885 GO:0046906 tetrapyrrole binding molecular_function 26.140331093318434 25.12547650595464 24.247285970424514 NA 20.93980053680536 19.969534833522488 26.00529101299445 24.80734907256949 25.240104546760673 25.54100434578167 25.76290687912229 24.908279077231864 26.912972699846968 24.491220874193 26.567827613588072 24.95609639437756 26.0220586609083 24.77104014657102 26.896915125724515 25.064777722463106 26.00315863225585 24.858638742073232 26.573215926492953 25.17412850001481 26.78558163678946 26.62928820760456 10.0 NA 8.0 6.0 29.0 10.0 29.0 10.0 28.0 17.0 31.0 6.0 25.0 3.0 24.0 4.0 51.0 16.0 23.0 3.0 25.0 5.0 47.0 20.0 2.0 NA 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0148545873637929 0.01934898020033666 0.03636675796689782 GO:0046914 transition metal ion binding molecular_function 29.348344537124234 29.527797240918122 28.860832509442464 28.87553773239553 29.50267022259867 29.271892378939015 29.39643039148258 29.448175914975074 29.44080992947309 29.63936941780057 29.38006901071947 29.577009033408327 29.621044059958038 29.342049648096317 29.949804502969087 29.76380632754241 29.165418915422677 29.46237870022344 28.980209157916725 29.751605806644072 28.92063595293817 29.400620837154232 29.151364803495067 29.465907679296237 29.425172320748192 30.024321510912852 327.0 276.0 344.0 343.0 358.0 434.0 394.0 444.0 434.0 413.0 484.0 368.0 458.0 449.0 342.0 446.0 517.0 515.0 393.0 392.0 405.0 393.0 470.0 462.0 5.0 3.0 3.0 4.0 6.0 4.0 6.0 5.0 7.0 6.0 6.0 5.0 5.0 6.0 6.0 5.0 7.0 5.0 6.0 4.0 7.0 5.0 7.0 6.0 -0.17945270379388845 0.10596880912720232 0.15148805703407617 GO:0046915 transition metal ion transmembrane transporter activity molecular_function 22.599183555796586 22.591823867638375 21.430955503582762 20.71397907417084 20.059459136264234 18.81900823931398 22.133865995717592 22.050081079031724 22.482202239028396 22.89204164178106 22.379764240098467 23.12917135845819 23.610913359471702 22.17272318789564 22.275235430334305 22.417251332281733 23.67328075897069 22.645901854800485 21.04907104619401 21.92706155700184 22.980990556008678 21.965752243796068 23.232769552146234 22.97886103819468 22.205596198086567 24.189534385609626 8.0 6.0 5.0 3.0 8.0 12.0 17.0 26.0 17.0 19.0 20.0 13.0 16.0 17.0 17.0 15.0 9.0 16.0 15.0 13.0 20.0 21.0 15.0 23.0 3.0 3.0 2.0 1.0 3.0 2.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 2.0 3.0 3.0 4.0 2.0 4.0 3.0 3.0 3.0 0.007359688158210531 0.7290344895388041 0.7743276961229171 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism molecular_function 27.429666896869684 28.44135771757829 27.25768916372116 27.832346066530906 26.952079635376247 28.198334819126725 27.06091842856728 28.40146238025639 27.136120944283018 28.358920920033583 27.553402749505572 28.47468224799233 27.4905749960892 28.174689239988194 27.103680445471763 28.838972209395685 27.18731845285872 28.668564902817 28.02684402202957 28.515881623557817 27.962345075721665 28.309811154623127 27.440186936513253 28.692991186187378 27.51559318710204 28.556757851458922 109.0 100.0 104.0 125.0 104.0 130.0 128.0 138.0 122.0 133.0 124.0 102.0 133.0 122.0 93.0 120.0 137.0 159.0 140.0 140.0 117.0 104.0 122.0 167.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0116908207086048 5.312128159411724e-05 0.0005099643033035255 GO:0046943 carboxylic acid transmembrane transporter activity molecular_function 23.040156276297804 26.03395416961752 22.58447329358412 25.572879619964205 21.769613224481454 24.979165945750562 22.5516221556787 26.117292510895496 23.270635366607 25.7341816904424 23.268467606703318 26.138008711894894 24.166207470196053 26.65869232016201 23.57567138168743 26.45180100443289 22.880521712150607 26.05050882818994 22.206127885696255 25.58807272168823 21.93107984055881 24.84933875293027 22.62527532682973 27.12796979419856 23.622178082388743 25.40667171400041 23.0 89.0 16.0 77.0 16.0 132.0 20.0 92.0 28.0 108.0 47.0 102.0 34.0 152.0 27.0 114.0 11.0 96.0 11.0 101.0 24.0 145.0 28.0 90.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 4.0 3.0 2.0 2.0 3.0 2.0 3.0 3.0 -2.993797893319716 3.225641456243767e-05 0.0005099643033035255 GO:0046982 protein heterodimerization activity molecular_function 22.481487279841488 22.312922507195253 21.454944289926818 17.946598677454432 20.79064996246405 22.14980991741027 NA 20.90944899715102 21.64253594318427 22.45849897754027 24.129510752383013 23.22681661506267 24.21322069311153 23.408163457195567 22.04708173445488 21.516392378019734 22.928469572078424 22.27421843281713 20.40198003151352 20.657481603124694 21.122044447276657 16.32060653058314 21.25568705024294 24.165515661776052 17.31992683694844 18.247252566958586 5.0 2.0 6.0 9.0 NA 7.0 7.0 3.0 13.0 11.0 13.0 10.0 6.0 9.0 9.0 15.0 6.0 6.0 7.0 2.0 8.0 9.0 1.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.16856477264623493 0.950924583799356 0.9577970205788449 GO:0046983 protein dimerization activity molecular_function 25.934514446812624 24.925598607886595 24.13482171916965 23.726288141240676 23.39881842568017 24.34479604770287 25.74485188573127 24.68094925051809 26.14487698451333 24.616585765571624 26.55591004228525 25.47261058223261 26.37021214842266 24.657984159054642 26.492995529372497 25.250177991908068 26.014105953987745 25.351787121806478 26.182707628807176 25.26240761890969 25.08986999556373 23.86846788691234 26.22939439997853 25.792638297719606 26.09130512096263 24.584646042014285 23.0 12.0 17.0 28.0 33.0 22.0 43.0 24.0 50.0 34.0 49.0 27.0 59.0 29.0 46.0 35.0 43.0 38.0 33.0 18.0 46.0 34.0 39.0 23.0 2.0 1.0 1.0 1.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.008915838926029 0.011074437676156606 0.022291771322328135 GO:0047112 pyruvate oxidase activity molecular_function 20.658150657381803 26.51641688279229 21.752255074841447 26.291146017124394 21.620249822525 27.81356077821321 20.927895600372537 26.07437708055723 NA 25.735679668508602 NA 24.58607633324953 18.54681837647819 27.50993000373569 21.66071295506409 26.48592343751209 19.606872851771193 24.698453810012303 20.353644775175127 24.732042834530038 19.900972408713766 26.59368975235278 19.040969706007505 27.271645509158944 18.750818041844504 26.229514638614372 12.0 25.0 10.0 47.0 9.0 26.0 NA 26.0 NA 17.0 3.0 25.0 10.0 36.0 4.0 24.0 7.0 19.0 3.0 34.0 3.0 34.0 4.0 29.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -5.858266225410485 7.612502462153449e-05 0.0006012913337194623 GO:0047154 methylmalonyl-CoA carboxytransferase activity molecular_function 23.639526153046273 24.924225273903488 23.050098305607985 NA NA NA 23.265806700891943 25.273287808626904 23.05620945373268 26.279677573715162 22.43311168128747 24.025637187063136 23.647096341708806 22.151848437401014 23.5445497005125 24.318803049327112 24.191369913518304 25.610076332071408 24.484750264642237 23.79120436750625 24.14028762527841 24.15568804046368 23.85026366393408 23.34388477337021 23.096944610013164 25.805039817181555 5.0 NA NA NA 4.0 10.0 9.0 11.0 5.0 6.0 7.0 3.0 9.0 11.0 5.0 10.0 7.0 9.0 10.0 10.0 11.0 9.0 5.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.2846991208572156 0.04864379368009331 0.07872902492059129 GO:0047429 nucleoside-triphosphate diphosphatase activity molecular_function 21.188688932964308 22.6103940985126 20.08830492711846 22.56602121510095 22.485228952314134 23.21138912674957 20.625647451781823 23.063439760316594 21.565747118825 21.59231313310529 21.4772594518756 21.772047831021148 22.03992630391647 23.065801869288567 21.070484429316085 22.05688711146306 21.3460169435472 21.837893350815854 19.39712659678102 22.68671998205804 19.72216599801903 21.8440647354619 19.567677315597013 23.963447535876927 21.277918851106964 20.64936516509291 4.0 8.0 10.0 9.0 4.0 7.0 4.0 6.0 4.0 4.0 5.0 7.0 7.0 8.0 8.0 9.0 3.0 10.0 4.0 7.0 4.0 11.0 6.0 7.0 2.0 2.0 1.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 1.0 1.0 2.0 2.0 1.0 -1.4217051655482926 0.0012242832644312096 0.0037265988146589013 GO:0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity molecular_function 22.09920570500805 22.85253765090875 22.487887345777068 21.347442646333924 22.50343112489116 22.947772982938734 21.699122064901147 22.97031170597684 19.94734246184924 22.740501789267 20.96036629738205 22.44719274961513 21.569518106578652 22.604447149838627 21.192436106597697 23.662772751349248 18.563796163046 23.35534827041303 23.887101663827643 21.85921811751421 22.168710600623 23.14250015128856 22.817656561811727 23.434168666528038 21.010724856475814 22.06693293788106 8.0 5.0 5.0 10.0 4.0 5.0 3.0 6.0 4.0 6.0 4.0 4.0 6.0 11.0 2.0 7.0 8.0 7.0 5.0 9.0 6.0 6.0 3.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7533319459007011 0.017926339076638688 0.03379466943753034 GO:0047473 D-alanine [D-alanyl carrier protein] ligase activity molecular_function 21.35726799495181 24.36041743544311 23.24546127254261 24.203937981844806 22.60150054682818 24.891975771659368 19.960203096262322 25.09885362871441 18.843086778671857 24.060524139950342 18.421805252354066 23.482164386332787 21.12344555064817 24.61310342582668 20.050390764256694 24.47925240495315 19.84586857787286 23.97276029001629 20.77897743827176 24.635994638199268 21.11075401443929 24.235062687857646 NA 23.861198646533733 21.528298235416468 23.957250234371124 11.0 13.0 8.0 13.0 4.0 16.0 2.0 12.0 2.0 11.0 3.0 12.0 3.0 11.0 2.0 13.0 5.0 14.0 4.0 13.0 NA 11.0 5.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.0031494404913026 4.865007418510381e-05 0.0005099643033035255 GO:0047553 2-oxoglutarate synthase activity molecular_function 23.41057419520589 23.26564167908791 23.5682261533126 NA 19.025367628482254 18.929960621356773 22.058759766742774 21.85484609097582 22.831942543301093 24.87464860943345 22.04907097400752 24.691933258530327 24.187324342856073 21.950455136164173 23.326351043765374 18.26117456263569 21.864424072523388 21.83704155517438 23.91800118062698 22.25925253462317 24.590128879373413 22.505553042915004 24.545668571257377 21.65383054427733 22.42266718771894 24.65325023733736 11.0 NA 2.0 2.0 8.0 6.0 12.0 14.0 10.0 13.0 14.0 8.0 11.0 3.0 5.0 6.0 13.0 8.0 15.0 9.0 15.0 8.0 11.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.1449325161179793 0.3247557654026184 0.4012639356708831 GO:0047905 fructose-6-phosphate phosphoketolase activity molecular_function 23.654116899631195 24.068492435629906 23.75018013746285 25.060538184811662 25.96254782731013 24.372367578348133 22.77171303211548 23.876466133961586 22.237332650209567 23.90388727909594 21.963110544935976 20.84545480986861 23.76306868641625 24.347471629043607 NA 23.220005274760165 16.102367664894214 22.26138408760964 22.63885363008427 24.941889243322553 24.1046889136096 24.51995926939126 17.916129225496835 18.442789017249282 23.30883841808497 24.771396017105488 8.0 14.0 12.0 9.0 6.0 12.0 9.0 8.0 7.0 6.0 6.0 10.0 NA 7.0 1.0 13.0 8.0 10.0 8.0 10.0 2.0 1.0 9.0 11.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4143755359987118 0.10955657678268572 0.15625898037119063 GO:0047952 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity molecular_function 20.476954788795727 22.533835216759204 22.36841487484118 22.03417197697796 20.070364307895293 22.204268818133684 18.513203967331624 23.03219870252892 NA 22.02076089742345 20.108246077080096 22.8265230061077 19.93154490340606 23.238516243666115 20.614478520753213 22.55497434528607 20.54630714418061 22.63631336740128 20.43938829430413 22.14077507308918 19.062600502878297 20.842894081961894 NA 23.30734427929077 18.83634966405369 21.934096998491725 7.0 7.0 5.0 5.0 4.0 8.0 NA 8.0 4.0 11.0 4.0 11.0 5.0 10.0 5.0 13.0 4.0 11.0 3.0 7.0 NA 10.0 2.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.0568804279634776 0.00036993149163163074 0.0014703009603703032 GO:0048037 cofactor binding molecular_function 31.42779436231645 31.683877329507073 31.434612010609946 31.070621518124394 31.433582174295047 31.531811498113257 31.36153734691414 31.916237800412322 31.16668802800989 31.824638662876982 31.423590402396087 31.633036679892093 31.30939950459701 31.123420550780157 31.7595827008182 31.86196421925623 31.299602222419033 31.81945897035738 31.89017543383736 31.91079021275084 31.470440823536485 31.7480270357592 31.02761807129345 31.405891838178807 31.345034430324645 32.01174800718616 476.0 315.0 390.0 454.0 735.0 705.0 795.0 755.0 867.0 757.0 862.0 523.0 904.0 666.0 707.0 745.0 1126.0 835.0 711.0 553.0 795.0 641.0 809.0 800.0 5.0 3.0 4.0 5.0 6.0 5.0 6.0 5.0 6.0 7.0 7.0 5.0 6.0 5.0 7.0 5.0 6.0 6.0 6.0 5.0 6.0 6.0 6.0 7.0 -0.25608296719062196 0.043308142810791976 0.0706517153305469 GO:0048518 positive regulation of biological process biological_process 25.80579391687964 26.48444786547768 26.05565030432896 25.78369447236692 24.50749332260889 26.53933912511453 24.828584149169327 26.52163551693025 26.787849567947067 26.41119799500486 26.526313016812306 26.77290346870976 25.749410219722648 26.27775308738893 26.01902753935662 26.436791805681953 25.36816054609713 26.740309433657288 25.21935911492652 26.439531646900658 24.885158442194466 25.591844329016237 25.76196850767327 27.216035677217164 26.127318079918513 26.412725777697634 135.0 172.0 86.0 179.0 125.0 289.0 225.0 281.0 216.0 247.0 150.0 187.0 139.0 335.0 150.0 318.0 151.0 233.0 117.0 151.0 179.0 317.0 203.0 260.0 2.0 2.0 2.0 4.0 2.0 2.0 6.0 5.0 4.0 6.0 5.0 4.0 2.0 4.0 4.0 4.0 2.0 5.0 2.0 2.0 6.0 4.0 2.0 4.0 -0.6786539485980398 0.009374768459434895 0.01937038251220985 GO:0048519 negative regulation of biological process biological_process 26.877996221108003 26.347331272900252 25.583186355582985 26.059854262685928 27.26125250998035 25.82243047264207 26.84652711096261 25.508141887401386 26.28531748822245 27.174210270533166 27.40728433730916 25.857024809219656 27.48311192534303 26.289231289018755 26.327921213154486 24.86249995920707 25.797514707448386 25.44097862539208 27.031860254674505 27.747042191943297 27.471972409423337 25.72237163522243 26.61440766477233 26.07320214161335 26.977575412758505 26.90878843470239 174.0 206.0 231.0 135.0 246.0 212.0 281.0 276.0 301.0 191.0 368.0 179.0 191.0 146.0 140.0 204.0 336.0 373.0 285.0 208.0 242.0 197.0 328.0 329.0 3.0 4.0 3.0 3.0 2.0 4.0 5.0 3.0 3.0 4.0 3.0 4.0 7.0 4.0 4.0 4.0 4.0 4.0 3.0 3.0 3.0 4.0 2.0 2.0 0.5306649482077503 0.04964722965745621 0.07872902492059129 GO:0048583 regulation of response to stimulus biological_process 22.938065291766016 22.69340044350089 23.470060966292657 20.53156117817559 18.160084816599586 21.142822540773167 NA 21.35304892930198 23.324099244957466 18.26466245935677 24.714224266415144 20.984488221543426 23.72475551345384 24.463415445044976 21.744951147303013 21.759992722463533 21.57438411379373 21.94913248808559 21.264422151029734 21.11173623812789 20.492188843633183 17.879124923201413 22.49905749711373 24.952553312626506 NA NA 18.0 12.0 6.0 14.0 NA 7.0 38.0 6.0 18.0 13.0 14.0 10.0 12.0 15.0 8.0 18.0 6.0 14.0 12.0 6.0 12.0 21.0 NA NA 3.0 3.0 3.0 5.0 NA 3.0 6.0 3.0 3.0 3.0 5.0 6.0 3.0 5.0 5.0 3.0 3.0 5.0 3.0 3.0 3.0 5.0 NA NA 0.24466484826512414 0.324206575396745 0.4012639356708831 GO:0048585 negative regulation of response to stimulus biological_process 21.312427826878906 20.90173757029197 21.8850984655715 18.946598677454432 16.575122315878428 19.036822482132038 NA 19.75054074741549 21.664848460866274 16.679699958635613 23.12926176569399 19.192332932132175 21.969198957499103 22.520796736641504 20.15998864658186 19.98760677269276 19.913101321240045 20.36416998736443 19.679459650308583 19.154067495449077 18.90722634291203 16.294162422480262 20.914094996392574 23.231664776463557 NA NA 6.0 4.0 2.0 4.0 NA 2.0 12.0 2.0 6.0 4.0 4.0 2.0 4.0 4.0 2.0 6.0 2.0 4.0 4.0 2.0 4.0 6.0 NA NA 2.0 2.0 2.0 2.0 NA 2.0 5.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA NA 0.4106902565869355 0.2908457067435437 0.36699677778858775 GO:0048856 anatomical structure development biological_process 21.66765523378481 21.542754144179067 20.89788006380794 20.46166341661628 21.549926837292475 21.830991073788468 18.69596105486389 21.28981360429545 19.337370683807613 20.071338762860048 23.297768055718823 22.12422992587561 22.041066237214064 21.534898301688038 22.081364938112173 22.177018270544337 21.73707257019588 21.39452478327933 20.412386439756574 20.05531946662297 18.096414254055773 21.311616441496074 22.64868160537128 22.353359774497903 21.54175786232252 21.803816433082428 5.0 7.0 10.0 5.0 1.0 7.0 5.0 2.0 8.0 7.0 7.0 6.0 4.0 9.0 7.0 9.0 7.0 5.0 2.0 1.0 6.0 6.0 9.0 5.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 0.12490108960574275 0.8173613313851769 0.8543274217493305 GO:0048869 cellular developmental process biological_process 22.701115713608733 24.18936626078177 24.25971096887305 23.3058867285948 23.97452989610847 24.67499820886261 20.56216187553508 23.76469398517416 21.027541671938238 24.10187278442017 22.573385309140573 24.28816678215922 22.71281921093417 24.630841210334182 21.610766666489635 24.21174644664337 21.369955885073274 23.67119509532768 22.30080798522477 23.80067396407559 22.590809392125248 24.07254591994864 22.855159978834518 25.27368897698888 21.72741266378521 22.94602661151671 18.0 10.0 14.0 27.0 6.0 18.0 3.0 16.0 13.0 23.0 16.0 17.0 8.0 21.0 14.0 22.0 11.0 16.0 11.0 17.0 16.0 21.0 13.0 20.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.4882505471730383 0.0006583371695572323 0.0022696264851033866 GO:0048878 chemical homeostasis biological_process 29.165086227444267 29.3233401549716 27.753985306492513 30.206452202102376 29.46074244412641 29.65994510863261 30.47960400843972 28.094047171506038 28.50701030174407 28.72208286790984 26.80469493836707 25.51500234865554 30.249188854434944 29.872655700238877 28.41979065797661 29.707958577337212 28.02920039347809 28.39282602494607 28.63652907737294 30.410869144980346 28.089977287842274 29.849113047184648 30.226988764051754 26.7812170668212 28.551689661344 28.820496698479303 68.0 38.0 19.0 47.0 82.0 82.0 57.0 50.0 60.0 41.0 43.0 70.0 52.0 49.0 51.0 57.0 55.0 69.0 44.0 46.0 71.0 48.0 64.0 57.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 2.0 -0.15825392752733336 0.6441672226837103 0.7073013587238495 GO:0050044 galactose-6-phosphate isomerase activity molecular_function 22.018685393640432 23.15724966683905 23.69351138319387 23.09834224007212 22.191165224950428 24.578472976923948 21.564751854625406 23.756611019417313 NA 21.64397222150527 20.441983445546448 23.46016146056735 22.65550854114002 22.829285296065702 22.342293541322718 23.396196535594488 20.713233080737727 21.953112402553504 23.09933081160038 22.07211913065237 19.132612010639228 23.242840181925768 18.855738285139974 23.173272676144023 17.446772897707564 21.460278097066237 6.0 7.0 7.0 12.0 5.0 10.0 NA 9.0 2.0 7.0 4.0 7.0 5.0 11.0 5.0 8.0 10.0 8.0 2.0 9.0 1.0 6.0 1.0 7.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.138564273198618 0.022774727854040278 0.04131229703756143 GO:0050109 morphine 6-dehydrogenase activity molecular_function 21.28816086198127 21.40477957051226 23.11265109527263 21.760160566001066 22.56194256413557 18.88408285202107 18.099201231077 20.525538564412155 NA 20.094856890787003 21.037813794005295 22.93164585402764 19.78420869622537 22.10660710568996 21.203400517116908 NA 20.379234812345963 18.86739332064861 16.82721767535049 20.073679279051266 20.922854881213954 22.153870123972386 NA 20.184262644391012 20.103957130081767 21.902196935852032 4.0 3.0 4.0 1.0 1.0 3.0 NA 4.0 2.0 4.0 1.0 4.0 5.0 NA 2.0 3.0 1.0 3.0 4.0 5.0 NA 2.0 3.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.11661870853098932 0.72477122130619 0.7743276961229171 GO:0050145 nucleoside monophosphate kinase activity molecular_function 25.591400731980485 24.997906232316733 23.742189806296572 23.26647302818296 21.757909987599703 23.99014206264357 26.53935334093984 25.38646945174693 25.590756173559278 25.91982121655709 26.325659365544595 25.47816473615829 26.511816875949147 24.50607552859898 24.95312088598975 24.653899460663208 25.661064989851585 25.21067721995951 25.890808182767053 25.02863272489841 24.621156911743412 23.958715670700197 25.13369571964721 24.6995332328062 25.60041321465437 25.69713785695669 26.0 10.0 10.0 11.0 36.0 25.0 32.0 31.0 33.0 34.0 43.0 22.0 37.0 27.0 34.0 34.0 42.0 37.0 27.0 17.0 43.0 29.0 38.0 34.0 4.0 3.0 3.0 4.0 4.0 3.0 2.0 4.0 3.0 5.0 4.0 3.0 3.0 5.0 4.0 5.0 5.0 3.0 2.0 4.0 4.0 5.0 5.0 3.0 0.5934944996637519 0.18420928818665294 0.2488021554728819 GO:0050193 phosphoketolase activity molecular_function 21.469995703522233 22.622294149861048 21.52100388465858 23.52531198568478 23.53837664934281 23.11513803881985 21.07778394536931 22.64003451862277 20.538732436951086 22.23473151122075 20.17496791209692 19.57990429780332 21.37185298308811 22.345462332561393 15.474053960996208 22.25448526004704 NA 21.562371394350272 18.960184776427106 23.381172887685644 22.41282687013137 22.584069459704185 15.962072289413026 NA 21.478928267394448 22.7314429952566 3.0 5.0 7.0 7.0 2.0 5.0 3.0 4.0 4.0 2.0 3.0 2.0 1.0 4.0 NA 8.0 2.0 4.0 5.0 7.0 1.0 NA 3.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1522984463388148 0.011468073022237554 0.023046948682371123 GO:0050418 hydroxylamine reductase activity molecular_function 21.729084062788687 22.055227739177994 20.442064176036748 NA NA 14.707044077160536 21.923256108478324 21.32595456982943 20.959683139260253 23.601825703483247 20.977108344159387 22.044275621069282 22.406247430117933 21.168222215749587 20.495608970404515 19.15768659437512 22.01013736235516 22.477255801209026 21.463793987285868 21.294008208681525 22.04615418391996 20.330376584365112 22.567043855816284 20.87431032156681 21.94441351374968 23.700744892753026 4.0 NA NA 1.0 9.0 4.0 4.0 7.0 6.0 4.0 7.0 4.0 6.0 3.0 5.0 7.0 4.0 4.0 5.0 3.0 6.0 5.0 5.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.3261436763893073 0.6695085659968565 0.7310119775713709 GO:0050446 azobenzene reductase activity molecular_function 23.73231756921084 24.2274046151798 24.740711383109875 23.824742558801194 25.163412417896925 24.06154854423827 22.471579872672358 24.793640013033308 22.135236541760587 24.916635738072237 21.910493137559047 23.95113523715881 21.187802500468603 22.976030877550105 24.84361770509841 24.24841269909551 23.43880530001245 24.47310941789081 23.769226205453204 24.656723246138235 23.87486921454225 24.039449293767124 22.33471944264101 23.904727752307274 23.005004222517677 23.885351197539592 18.0 17.0 20.0 13.0 11.0 17.0 11.0 15.0 10.0 12.0 6.0 11.0 15.0 17.0 15.0 21.0 18.0 18.0 12.0 14.0 15.0 12.0 13.0 15.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.4950870459689618 0.04964722965745621 0.07872902492059129 GO:0050480 imidazolonepropionase activity molecular_function 21.960081337440034 21.028758374985603 23.18535868314007 20.858303004685013 23.266543396797207 20.241708810677842 20.158486079461188 20.38757632409121 20.858765524584122 20.112731109200272 22.41962328896112 21.60661383794863 22.599165012196288 18.906348571360926 19.228982027788586 20.78743382397216 21.445408241739774 17.351051131641785 20.98615088556071 22.792560249035017 21.979486483223013 20.34164538918733 19.771625165001822 NA 21.825054450006515 21.79203148363982 4.0 4.0 6.0 6.0 2.0 3.0 1.0 3.0 4.0 3.0 5.0 1.0 4.0 3.0 3.0 1.0 4.0 7.0 7.0 5.0 1.0 NA 4.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.9313229624544306 0.09656589443461913 0.14111737266323732 GO:0050511 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity molecular_function 19.982290946777663 20.511796886802173 NA 20.094474714194746 16.931771518517294 20.681278510266498 19.81715252943116 18.823855753818787 21.738669011401615 19.94220592809853 20.121322598562426 18.11476550669465 17.333316979512652 20.404808324959973 NA 22.232091916449367 18.982631571454547 20.5236015840284 19.445524955018282 19.54463745952318 18.425493731618033 19.938646584471297 20.79528516265424 21.635761449104194 20.069318323310128 19.028263615590085 NA 5.0 2.0 10.0 3.0 3.0 8.0 4.0 3.0 2.0 1.0 3.0 NA 12.0 2.0 6.0 3.0 5.0 3.0 5.0 4.0 11.0 4.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5295059400245101 0.29142131954205963 0.36699677778858775 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity molecular_function 24.64430682683276 25.92281709654911 25.153983164865355 25.60250760357254 25.11302148410297 25.60058653312922 24.10287367517445 25.828632272175522 24.84661588850494 25.770509883295695 24.574651720531392 26.09260099639393 25.069640244834904 25.883868343015536 24.44779489624041 25.994054688674666 24.093137658096857 26.184252357888607 24.46244625527821 26.27058792726345 24.08360715679564 25.59836484982068 24.531978680080968 26.125405513490982 24.67183033149137 25.91291573732299 43.0 55.0 50.0 50.0 40.0 69.0 50.0 85.0 49.0 69.0 58.0 67.0 49.0 66.0 36.0 72.0 57.0 78.0 39.0 65.0 53.0 79.0 48.0 84.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.2785102697163495 3.225641456243767e-05 0.0005099643033035255 GO:0050661 NADP binding molecular_function 29.7227709228768 30.459118417992567 30.237723162675987 29.991633749924144 30.34902272472052 30.482142294094466 29.647622582113772 30.659212352515468 28.789229811458693 30.49292669025108 29.342687897027112 30.30485554517037 29.209467088739324 29.848232712479874 29.958551049142645 30.73003379176903 29.418957774467525 30.63549347136989 30.341437411607426 30.677189965949093 29.979837151717323 30.609972326012702 28.885040031723968 30.165303447650643 29.4152016402756 30.608453645679496 102.0 92.0 98.0 111.0 107.0 142.0 123.0 145.0 133.0 152.0 136.0 112.0 142.0 140.0 125.0 142.0 143.0 156.0 125.0 122.0 122.0 132.0 113.0 156.0 NA NA NA NA NA NA 1.0 NA 1.0 NA 1.0 NA NA NA 1.0 1.0 NA NA NA NA 1.0 NA NA NA -0.7363474951157656 0.0006583371695572323 0.0022696264851033866 GO:0050662 coenzyme binding molecular_function 31.17229671149176 31.57472038446567 31.324772885321693 31.023180015547695 31.389290611545743 31.50716259120356 31.10128910672401 31.794388583053646 30.818508444691272 31.674208417360802 31.13132618822548 31.446815156276337 30.948360022922174 31.03258539450263 31.49697718860529 31.78850308457934 31.011537289946087 31.68551454797297 31.66218841276398 31.803576805802397 31.27483481353667 31.67682605715249 30.560697699191238 31.30234289081657 30.99454054362488 31.853227004917716 363.0 281.0 305.0 361.0 519.0 534.0 574.0 543.0 629.0 549.0 578.0 418.0 650.0 514.0 510.0 544.0 745.0 652.0 480.0 430.0 545.0 498.0 537.0 559.0 8.0 6.0 8.0 6.0 8.0 8.0 7.0 9.0 7.0 8.0 8.0 8.0 8.0 9.0 8.0 9.0 9.0 8.0 9.0 8.0 8.0 8.0 8.0 8.0 -0.40242367297391013 0.0032349119169146935 0.007931571851295751 GO:0050789 regulation of biological process biological_process 32.274598603407576 32.91137995389892 32.34503664132787 32.51844094133228 32.45085354489247 32.78481496916016 31.90033170708373 33.153123616232484 32.128035150321544 33.108160199658535 32.3122602646832 33.02994024489274 32.329825809793675 32.77885773951356 32.23577939885994 32.80483795321028 31.658081976773 32.814265595450436 32.72943652006898 33.34734470692238 32.444457151154005 32.59692251329437 32.140262916265094 32.81020182857761 32.341256149865764 32.97214165916129 4152.0 4792.0 4027.0 4647.0 4421.0 6579.0 5207.0 6840.0 5918.0 6130.0 6017.0 5297.0 4625.0 6082.0 3795.0 6397.0 7323.0 7449.0 5105.0 4660.0 4724.0 6359.0 5997.0 7099.0 6.0 7.0 8.0 7.0 5.0 8.0 12.0 8.0 11.0 11.0 11.0 10.0 9.0 8.0 9.0 10.0 10.0 12.0 7.0 7.0 10.0 9.0 5.0 8.0 -0.6367813504913471 5.312128159411724e-05 0.0005099643033035255 GO:0050790 regulation of catalytic activity biological_process 22.947099431404304 22.22259372653985 NA NA NA 15.256093142867355 20.260683610237805 18.134077892780336 23.84899798545074 22.857116838511697 21.08285906238033 24.829286377066087 24.44384319672193 22.01000843346929 23.464640038464733 NA NA 18.801423922282005 19.98270039841432 15.831689969714345 NA NA 21.30222291238184 19.64791832152641 NA 19.52007088367155 NA NA NA 2.0 2.0 5.0 8.0 13.0 5.0 13.0 10.0 3.0 5.0 NA NA 5.0 4.0 5.0 NA NA 8.0 5.0 NA 3.0 NA NA NA 1.0 2.0 2.0 3.0 3.0 2.0 3.0 4.0 2.0 2.0 NA NA 2.0 1.0 2.0 NA NA 2.0 2.0 NA 2.0 0.7245057048644554 0.0807162584311211 0.12314656543036569 GO:0050794 regulation of cellular process biological_process 30.068460031967557 30.72022466606798 30.143116422610955 30.32998231355321 30.178315833054285 30.577397005433397 29.752948769727226 30.99892222963555 29.88218905725305 30.88346782978632 30.094025324484463 30.810925114943146 30.10580945938809 30.64055741809421 30.003939803445906 30.64869860112166 29.50144760075209 30.621678780877534 30.59096145658025 31.10703029182148 30.19401343983828 30.397333398543534 29.957445994541807 30.698288316017514 30.147944531124143 30.734175280445115 871.0 1011.0 828.0 993.0 901.0 1421.0 1035.0 1448.0 1207.0 1322.0 1236.0 1150.0 981.0 1326.0 804.0 1370.0 1505.0 1581.0 1052.0 1005.0 969.0 1381.0 1220.0 1494.0 6.0 6.0 7.0 6.0 6.0 7.0 10.0 6.0 8.0 9.0 8.0 8.0 8.0 7.0 6.0 7.0 7.0 8.0 8.0 6.0 8.0 7.0 6.0 10.0 -0.6517646341004237 6.784570247173055e-05 0.0005498145239267514 GO:0050801 ion homeostasis biological_process 28.98295576366846 29.1516393321842 27.571970408426992 30.03623300574257 29.290722119021783 29.489562666456198 30.30986265118025 27.921899713351657 28.317543837933478 28.55205071999802 26.45627799358677 25.34582032852836 30.05675932956676 29.698485562801565 28.218224152913585 29.537201485549478 27.85584400946108 28.22013602845557 28.46043202690466 30.240688364942503 27.89528915243421 29.679128107108887 30.055381396580554 26.54833205424355 28.366907456152806 28.65161075141539 58.0 32.0 16.0 40.0 72.0 72.0 50.0 44.0 52.0 36.0 36.0 62.0 44.0 42.0 44.0 48.0 46.0 60.0 38.0 40.0 62.0 40.0 58.0 52.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.16868356851573907 0.5637028616507731 0.6360770084449954 GO:0050896 response to stimulus biological_process 28.5931484935478 28.968142600599798 27.841685313880035 28.918873278874283 28.09214948314149 29.11478540828714 28.52878265659375 28.64838610772945 28.329779277970662 28.551235663544563 28.660466321246844 28.97307758391288 29.125656521233267 28.99782658030961 28.59046562398243 28.83011960978152 28.178669798278488 28.98027851665541 29.399405225293012 29.54557883361413 29.107640674829213 28.483738954189693 27.976150873158 29.293138083810305 28.33825515863331 28.93202462858174 394.0 451.0 380.0 608.0 467.0 563.0 715.0 475.0 713.0 690.0 783.0 713.0 518.0 675.0 452.0 661.0 809.0 805.0 402.0 339.0 521.0 873.0 707.0 566.0 7.0 7.0 6.0 7.0 7.0 7.0 7.0 6.0 7.0 7.0 8.0 8.0 6.0 8.0 7.0 7.0 6.0 8.0 6.0 6.0 6.0 9.0 6.0 6.0 -0.37499410705199665 0.03766692222862868 0.06276144050911694 GO:0050992 dimethylallyl diphosphate biosynthetic process biological_process 26.03971276891523 26.193093805185388 25.341608529383464 NA NA NA 25.47953932513622 25.938813071807104 26.58252923638784 27.26158719740723 25.801092050199752 26.68251104262368 26.35332241706475 25.266228493814715 26.36646645992679 24.95226549346075 25.678922267811288 26.007340652032447 26.08396026518525 26.236909127295704 26.04315196733201 25.414121153396135 26.549549454059573 25.732812597371662 25.4573490903206 26.770044488159336 21.0 NA NA NA 24.0 29.0 47.0 32.0 29.0 26.0 31.0 18.0 35.0 19.0 29.0 26.0 30.0 35.0 27.0 24.0 38.0 25.0 29.0 26.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.15338103627015798 1.0 1.0 GO:0051082 unfolded protein binding molecular_function 28.945968654475752 30.278434443033863 28.796034030885924 29.51557647883008 28.11122299314795 29.67853147423705 28.676569594289635 30.46559510786172 28.16352622052457 30.58024232093232 28.64089536417329 30.240110783419407 29.002126348150988 30.03964715966957 28.691132315393173 30.380363340674833 28.625140992241157 30.213136264202703 30.560581073532198 30.76442958376312 28.70231673467105 30.103348168461856 28.63747058202432 30.099560761803644 28.833202939062037 30.72183752582418 170.0 101.0 139.0 200.0 167.0 189.0 213.0 213.0 189.0 199.0 195.0 149.0 228.0 197.0 166.0 197.0 274.0 257.0 193.0 208.0 206.0 187.0 186.0 251.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.3324657885581104 0.0002755038114342687 0.0011655212090507369 GO:0051128 regulation of cellular component organization biological_process 25.367315697778746 26.977180653576468 26.239278396506794 26.607305168393026 25.253246893902613 26.2665738640341 24.73229168381296 27.22294782899477 25.035235219106468 26.889163343023558 25.330028658157072 27.20856970269887 25.4644455052636 27.25871462849576 25.16174494170897 27.106646660861678 25.052477413373104 26.856469581608852 25.81197895452571 27.058988353723787 25.01680312932041 26.392464583223877 25.107969807656602 27.712026731090745 25.519844633735445 26.454612740163583 91.0 128.0 80.0 123.0 77.0 195.0 77.0 201.0 105.0 199.0 119.0 166.0 95.0 193.0 88.0 207.0 141.0 209.0 96.0 142.0 102.0 216.0 114.0 181.0 2.0 2.0 2.0 2.0 2.0 2.0 4.0 2.0 4.0 4.0 4.0 2.0 2.0 2.0 2.0 2.0 2.0 4.0 6.0 2.0 5.0 2.0 2.0 4.0 -1.6098649557977218 3.225641456243767e-05 0.0005099643033035255 GO:0051171 regulation of nitrogen compound metabolic process biological_process 29.04213338260628 29.532857478853984 29.116938136075593 29.13489846497608 29.14235246593591 29.56171794072905 28.69527370409212 29.787347386685077 28.95360870547057 29.643408374414225 29.020712722165108 29.66957873146153 29.024712772275123 29.413267956117245 29.1493289856377 29.41781744691225 28.518103625330486 29.39401998906728 29.465251668803216 29.91193174207789 29.15964873958979 29.29735080241047 28.96042780772161 29.374667997871036 29.087047295046233 29.604352694536143 325.0 347.0 310.0 364.0 342.0 498.0 442.0 516.0 474.0 479.0 463.0 387.0 397.0 474.0 310.0 482.0 566.0 548.0 395.0 347.0 384.0 475.0 474.0 534.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 6.0 5.0 5.0 5.0 5.0 5.0 -0.4907240962477033 0.0002755038114342687 0.0011655212090507369 GO:0051172 negative regulation of nitrogen compound metabolic process biological_process 23.044278302780658 22.315145797952 21.41214146249033 22.123905356013807 23.34454722572457 21.464966997040502 23.110497575171646 21.432995309343905 22.314308854459767 23.25187540296093 23.68585729297481 21.919689955566135 23.812992973822926 22.341672231266713 22.376299452152203 20.233594686557442 22.258466493041034 21.136447241762994 23.427862798392635 23.731985596055303 23.42759588328258 21.773062944968924 22.57044361562043 21.78018752324883 23.035544801111804 23.00123485684784 11.0 14.0 17.0 7.0 18.0 14.0 26.0 19.0 26.0 12.0 31.0 14.0 15.0 8.0 13.0 12.0 26.0 24.0 17.0 14.0 22.0 13.0 28.0 22.0 1.0 3.0 3.0 1.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 1.0 1.0 3.0 2.0 3.0 2.0 1.0 3.0 3.0 3.0 1.0 1.0 0.7291325048286588 0.02092133533779403 0.038284203081476474 GO:0051173 positive regulation of nitrogen compound metabolic process biological_process 23.12539954596098 23.563278475679216 23.334516904204346 22.836300686683693 21.80012263499185 23.646347246397585 22.113544460556717 23.61284825180973 24.098085503508692 23.47296210293128 23.77193834524926 23.86549170229229 23.013627492796697 23.47721515374779 23.79752608099778 23.554672944444608 22.59686917343979 23.423391513358112 22.49810363950518 23.461846831634325 22.18471872405338 22.79775317251947 22.83598375324944 24.337232934420786 23.415115256825253 23.6408295134818 19.0 24.0 12.0 26.0 18.0 42.0 34.0 42.0 32.0 36.0 22.0 26.0 24.0 50.0 21.0 46.0 22.0 34.0 18.0 22.0 24.0 46.0 30.0 38.0 3.0 2.0 2.0 2.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.4378789297182344 0.04964722965745621 0.07872902492059129 GO:0051179 localization biological_process 31.147269296567718 31.73959565732693 30.95468379639119 31.55053014808092 30.86905171883589 31.211622424441863 30.909902458754054 31.65208973133534 30.922693444726953 31.61771676624873 31.316866097217172 31.840490979721174 31.45073870250717 31.675538729366668 31.090798581585087 31.997700970234323 30.75595848776555 31.7190856726363 31.4004129155904 32.041179490462454 31.21628349708049 31.55240370406261 31.154590207218213 31.80830066702451 31.489169362950047 32.00115523119557 1937.0 1855.0 1820.0 1925.0 1925.0 2113.0 2091.0 2508.0 2338.0 2642.0 2540.0 2039.0 2328.0 2305.0 1773.0 2312.0 2649.0 2818.0 2123.0 2166.0 2230.0 2210.0 2510.0 3121.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 4.0 4.0 4.0 -0.5923263607592126 0.00010962068302139599 0.000648372570666835 GO:0051184 cofactor transmembrane transporter activity molecular_function 20.690300988997407 19.793830409182664 16.321839686452385 16.888011937635184 NA 20.930570963153787 18.928377478475415 20.26832262945437 18.619426144885075 19.68359694297288 21.241137677347968 19.611167694949785 21.51043637591959 18.53439960892279 22.371006056573854 20.92724776230729 19.58540060420521 19.308143106317075 21.162263600134253 18.5354166992792 20.2866397610642 19.69964659484237 20.292861760654755 18.666778167560686 19.989645962820823 20.20795432806398 1.0 1.0 NA 2.0 5.0 5.0 3.0 4.0 10.0 4.0 13.0 2.0 5.0 3.0 8.0 4.0 2.0 2.0 4.0 4.0 3.0 2.0 6.0 4.0 1.0 1.0 NA 1.0 1.0 2.0 1.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 1.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 0.8964705798147428 0.17573433564422514 0.23995235326476255 GO:0051186 cofactor metabolic process biological_process 31.37551291038539 31.82505214828317 31.26998342700738 31.155838114060195 31.017566443194603 31.827225403284803 30.930715953390703 32.03956707435771 30.879545895808665 31.746979378237356 31.598987500918582 31.67467715271421 31.33874486682421 31.289843275617073 32.003968402755625 32.16741065592247 30.778752426430092 32.31763927482964 32.14116901712422 32.07955429008641 31.45601635090309 31.683816762857475 31.040675449238385 31.821558082287197 31.296278468446022 31.67127132223901 900.0 862.0 954.0 1042.0 1272.0 1564.0 1433.0 1383.0 1375.0 1404.0 1481.0 1138.0 1569.0 1410.0 1133.0 1278.0 2091.0 1694.0 1315.0 1104.0 1443.0 1381.0 1509.0 1350.0 11.0 10.0 8.0 10.0 12.0 10.0 8.0 12.0 12.0 14.0 13.0 10.0 9.0 12.0 12.0 11.0 14.0 14.0 13.0 11.0 11.0 11.0 11.0 12.0 -0.44953923789778116 0.009374768459434895 0.01937038251220985 GO:0051187 cofactor catabolic process biological_process 21.631323356778392 22.385966233495374 19.94113959091284 21.058936281929864 19.942851447873824 23.38261693976528 19.375767620282787 22.033940519237067 21.173061949850872 22.689084282889155 19.832689277784635 22.090368895931366 23.14895482528307 23.814812102897267 20.052385491384626 21.31536829164773 20.01215624328968 21.741015139271145 23.58591101133252 21.914975873016488 20.97598208249723 21.303382413457566 22.196246526758895 21.130155431342626 20.99059431275416 22.822837175968505 5.0 1.0 3.0 3.0 4.0 10.0 11.0 15.0 5.0 13.0 16.0 20.0 3.0 9.0 5.0 9.0 19.0 13.0 9.0 9.0 9.0 8.0 9.0 19.0 1.0 1.0 2.0 2.0 3.0 1.0 3.0 3.0 1.0 3.0 4.0 4.0 2.0 2.0 2.0 1.0 3.0 4.0 3.0 3.0 2.0 2.0 3.0 3.0 -0.7546428767169822 0.017926339076638688 0.03379466943753034 GO:0051188 cofactor biosynthetic process biological_process 29.30553747342239 29.79955199530841 29.218494939404177 29.12093631727027 29.027817564860676 29.813667365499025 28.83907985737691 30.024430881729337 28.77094589686068 29.705061364631074 29.53373867383883 29.64061855110517 29.268812241386264 29.240442531340808 29.95331347138273 30.16789404774713 28.666818223956213 30.31499455961004 30.06783113305417 30.04059037857305 29.38666058291254 29.652981861590856 28.95847056529349 29.81301239285585 29.19163032659848 29.599965438767686 211.0 211.0 231.0 265.0 317.0 402.0 359.0 353.0 348.0 351.0 377.0 279.0 392.0 365.0 289.0 337.0 524.0 426.0 322.0 273.0 369.0 359.0 390.0 341.0 4.0 5.0 4.0 6.0 5.0 5.0 3.0 6.0 5.0 7.0 6.0 5.0 5.0 8.0 6.0 7.0 7.0 7.0 6.0 6.0 6.0 6.0 5.0 6.0 -0.4940145218860188 0.007911788680711459 0.016907384030013527 GO:0051213 dioxygenase activity molecular_function 26.968708272723962 25.741754476305985 23.929531002575448 24.0854256317687 22.509998587711507 21.364278125011886 27.25651931989852 26.249160309920807 27.476166308360238 26.998319349826627 27.695120555519072 25.74923524635214 27.7556556386874 24.860781625309286 28.16644701477313 25.191347334820186 25.889744788145137 26.13549811343198 26.27795082342011 26.118814382392816 26.111836014522734 25.36970210959761 27.058946763215122 24.917138111632056 26.659727749433483 26.45813685649327 21.0 7.0 13.0 7.0 39.0 25.0 62.0 34.0 45.0 23.0 49.0 19.0 81.0 21.0 32.0 19.0 37.0 37.0 38.0 29.0 52.0 26.0 47.0 23.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA NA 1.2269537964179769 0.03266344168491133 0.055917661485280296 GO:0051234 establishment of localization biological_process 30.93693855478095 31.54982632740524 30.7219797927364 31.245921590273298 30.66743873401901 31.130484445659672 30.64797580978468 31.482684944744392 30.738696364017482 31.44243710710607 31.08998606460104 31.638306369405605 31.21704617312316 31.41494953019897 30.854471345085678 31.86525829336913 30.59589506953622 31.620706429790722 31.24242034168423 31.771139647751003 31.09843048336824 31.37900672515708 30.95227930302675 31.646624459492745 31.19230978734447 31.77277357283247 1641.0 1592.0 1539.0 1692.0 1634.0 1847.0 1808.0 2121.0 1966.0 2198.0 2138.0 1737.0 1994.0 1973.0 1491.0 1986.0 2173.0 2408.0 1845.0 1845.0 1921.0 1887.0 2122.0 2627.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.612887772624287 6.784570247173055e-05 0.0005498145239267514 GO:0051246 regulation of protein metabolic process biological_process 27.710522391778817 28.02189829658958 27.785811110486 27.61052475185279 27.685057982337927 28.24807232994214 27.432180142365603 28.292522328394014 27.60861171583693 27.956459215478702 27.673570694984107 28.14023477766032 27.652379907516647 27.95352392778232 27.89672263618701 27.91037360013278 27.30702283082431 27.87517888376749 28.118285028295155 28.297465292573012 27.75605207430425 27.86284314024807 27.70829626701576 27.889476600387937 27.74113139459157 28.064394374366326 86.0 82.0 80.0 105.0 89.0 133.0 122.0 128.0 124.0 129.0 107.0 93.0 114.0 138.0 87.0 136.0 144.0 134.0 100.0 88.0 106.0 131.0 108.0 131.0 2.0 3.0 3.0 3.0 3.0 4.0 5.0 4.0 3.0 3.0 3.0 3.0 4.0 2.0 3.0 4.0 4.0 4.0 2.0 3.0 4.0 4.0 2.0 2.0 -0.31137590481076316 0.0022136919545913893 0.006045268182341475 GO:0051252 regulation of RNA metabolic process biological_process 26.41987409316952 27.6679016483908 26.68815957251985 27.31927252240216 27.053001038258106 27.086609200758843 25.64278333830577 27.93904217566957 26.310103247168108 28.09215949877245 26.298453511534976 27.782207495110587 26.50300278178215 27.41752398308895 26.094645135884427 27.6025330967443 25.191970779408802 27.60049372451993 26.976800781691733 28.238145645940534 26.820467911490887 27.26626912505908 25.945203699605013 27.42565065360513 26.448309633647078 27.77529230215115 119.0 146.0 116.0 129.0 116.0 189.0 108.0 198.0 145.0 159.0 163.0 164.0 118.0 156.0 92.0 170.0 204.0 220.0 147.0 135.0 101.0 171.0 157.0 204.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.248027555221281 3.225641456243767e-05 0.0005099643033035255 GO:0051258 protein polymerization biological_process 25.51165598896905 26.564549731997534 26.198828797352448 26.24249660329623 25.538057334063073 25.677750397309605 24.364211433075344 26.676883979385142 24.05437245978187 26.651122460457568 24.383889007429186 26.79633023955299 24.84070120677455 26.41327182883295 25.971421157624448 26.94411015517011 25.22081153699517 26.45931165825425 26.285677308511826 27.05729690859837 26.088510447491192 26.15864922559546 25.928617008299824 26.712229664054483 25.078447559241585 26.47747571395213 30.0 14.0 16.0 21.0 24.0 29.0 14.0 30.0 24.0 29.0 20.0 15.0 36.0 32.0 18.0 30.0 41.0 33.0 31.0 21.0 29.0 30.0 24.0 30.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.0528937430284842 0.00021985068263840352 0.0009941074345388681 GO:0051259 protein complex oligomerization biological_process 24.00932345756886 23.96889877483922 22.85788506699349 21.49399380110313 22.119891799567966 23.036685856208834 22.015164663067583 23.474053272179194 22.89670693909558 24.231283833640656 25.40418247184587 24.798536764289647 25.661231723485628 24.968033596961412 24.064337635902014 23.3643576524432 24.266397265297122 24.02889388369159 22.78931735709317 23.312485780576647 23.581338358565983 20.639244549561592 24.327801116403823 25.46538970132867 21.181116002017653 22.476053951180944 16.0 8.0 15.0 16.0 2.0 24.0 16.0 10.0 31.0 32.0 28.0 28.0 17.0 28.0 22.0 43.0 18.0 20.0 18.0 9.0 22.0 26.0 5.0 5.0 2.0 3.0 2.0 2.0 NA 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 4.0 3.0 2.0 2.0 3.0 3.0 3.0 2.0 0.04042468272963973 0.9080725552559752 0.9266349541778063 GO:0051266 sirohydrochlorin ferrochelatase activity molecular_function 21.609308828490988 21.12590859484669 16.221266265055498 NA 24.326144783110948 18.871532802235123 18.996739501894343 20.52409874719955 19.883226097580792 22.69508809959413 15.876333394422096 21.50807160704005 21.835300408610287 20.240849470180237 16.52545470837626 19.17056428130296 19.517931239378512 20.81107404288998 21.198299655290565 21.17613040867666 21.909220872511668 19.282826263703576 21.002900212765454 20.009505290888754 21.363812748909787 22.437511960504327 1.0 NA 1.0 1.0 4.0 3.0 5.0 9.0 2.0 7.0 11.0 5.0 1.0 1.0 5.0 3.0 8.0 10.0 7.0 2.0 11.0 5.0 10.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.48340023364429996 0.6665990972678644 0.729111019623396 GO:0051276 chromosome organization biological_process 28.426925716959893 28.68668038990398 28.330600475004953 27.886419529153446 27.719826550942802 28.06973552828001 28.246650710602264 28.442387894070354 27.789280885898656 28.864884937215482 27.96450527227051 28.95552973015275 28.371862715523854 28.623548124005215 29.336299320719515 29.275789411164926 27.71689475225847 28.552543552005144 27.986256904751304 28.56644890727961 29.55550447035041 28.844023810973354 28.6897278821629 28.92093964190261 27.75081832274069 28.699410729319958 41.0 44.0 37.0 50.0 50.0 45.0 46.0 42.0 68.0 61.0 66.0 86.0 46.0 80.0 34.0 46.0 70.0 68.0 55.0 39.0 60.0 81.0 60.0 75.0 3.0 3.0 2.0 3.0 3.0 3.0 1.0 3.0 4.0 3.0 3.0 4.0 2.0 5.0 3.0 3.0 2.0 5.0 4.0 3.0 3.0 4.0 2.0 4.0 -0.25975467294408716 0.04964722965745621 0.07872902492059129 GO:0051290 protein heterotetramerization biological_process 22.585640664760927 22.38802193069393 21.57087351792717 17.946598677454432 21.040622212601832 22.036685856208834 NA 20.96548755615959 21.64253594318427 22.45849897754027 24.322890676621995 23.44377347554396 24.27476178054293 23.584987360213297 22.112676590645155 21.531226960522947 22.928469572078424 22.27421843281713 20.40198003151352 20.657481603124694 21.38724516265165 17.602829080752393 21.310211380806727 24.19743798553101 17.31992683694844 18.247252566958586 6.0 2.0 7.0 8.0 NA 8.0 7.0 3.0 14.0 12.0 13.0 10.0 7.0 9.0 9.0 15.0 6.0 6.0 8.0 3.0 9.0 9.0 1.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.19761873406699593 0.8055405886674939 0.8462244567820139 GO:0051301 cell division biological_process 27.079730394328962 26.923852926716233 26.431336408496342 26.42192675746871 25.698987043426214 26.509698664386665 27.273773464074807 26.85865023609338 26.08379315776907 26.42111302636993 26.937546594364978 27.249581317475585 27.671418942926003 27.143304588713907 26.30024972701184 27.185497828337148 27.3692835504323 26.74054740627573 26.890065505601438 26.83224855218172 27.064410060900155 26.30216542116158 28.21035091973373 27.543616856585786 27.162221044029287 27.256902178431567 91.0 127.0 88.0 158.0 103.0 188.0 110.0 166.0 119.0 209.0 157.0 170.0 120.0 234.0 104.0 205.0 129.0 191.0 120.0 147.0 127.0 235.0 133.0 197.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.15587746761272925 0.7290344895388041 0.7743276961229171 GO:0051336 regulation of hydrolase activity biological_process 22.46124131196888 21.72423714998517 NA NA NA 15.256093142867355 19.260683610237805 17.812149797892967 23.364795876834346 22.39633801110114 20.760930967492964 24.324232712284022 23.8539524303615 21.42504593274813 23.14271194357736 NA NA 18.479495827394643 19.98270039841432 15.509761874826982 NA NA 20.74299553562697 19.325990226639046 NA 18.9351083829504 NA NA NA 2.0 1.0 4.0 6.0 10.0 4.0 10.0 7.0 2.0 4.0 NA NA 4.0 4.0 4.0 NA NA 6.0 4.0 NA 2.0 NA NA NA 1.0 NA 2.0 4.0 5.0 2.0 4.0 4.0 2.0 2.0 NA NA 2.0 1.0 2.0 NA NA 3.0 2.0 NA 2.0 0.7370041619837089 0.10086095426924907 0.14722160342458812 GO:0051536 iron-sulfur cluster binding molecular_function 28.26756375284355 27.008331933083873 26.510937995922607 24.0968585253724 25.922563953945012 25.08449513032424 28.305052534902078 26.92815507547423 28.70567452472331 27.450952054462427 28.61856152897921 27.679340081263447 28.55203242226624 26.17151571671177 28.819883357968354 26.95749319479209 28.202048118572932 27.46773984220533 28.018351076415314 27.388104109329408 27.812343264225802 26.44328602749948 28.725737199185602 26.69083487145028 28.607925253480825 28.02737794411346 93.0 29.0 63.0 72.0 173.0 150.0 175.0 196.0 197.0 180.0 236.0 93.0 221.0 142.0 157.0 188.0 289.0 156.0 190.0 111.0 206.0 126.0 212.0 206.0 3.0 2.0 1.0 1.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 1.2592318197596768 0.00268017172806849 0.006910856026093958 GO:0051537 2 iron, 2 sulfur cluster binding molecular_function 25.661221729062465 24.47007106530065 24.964981832919825 17.361819140909006 NA NA 25.69031134499157 24.685139712794843 24.668670887821946 25.554871260429827 25.807719404538744 25.47041559996932 26.449267729213 23.146502082041287 25.10081557050745 23.104708442656225 24.79912119391212 24.147818704398198 25.632543055098925 24.123235377679247 26.055528646197434 22.985499690008325 26.433343359657503 23.034318224787267 25.331302653458554 25.85390852906453 28.0 1.0 NA NA 40.0 17.0 37.0 32.0 35.0 33.0 40.0 8.0 29.0 7.0 30.0 16.0 47.0 20.0 32.0 13.0 36.0 8.0 33.0 27.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.1911506637618139 0.006428241403275216 0.014507134306125623 GO:0051539 4 iron, 4 sulfur cluster binding molecular_function 27.84320845628163 26.59973767703064 25.79800890241593 24.051914962509212 25.916882994535154 25.076987172975386 27.909525874385533 26.26937758252349 28.537159344430407 26.752650143865523 28.191689070965552 27.1105668489638 27.79396666782103 25.90716058850402 28.578806347883592 26.799880052120038 27.950867229022933 27.123566921109944 27.43431513295623 27.15766921408356 26.605029858947052 26.216161112314268 28.198996515016827 26.526375299308967 28.319167787988025 27.4108048861385 54.0 27.0 62.0 71.0 92.0 103.0 100.0 127.0 121.0 106.0 136.0 71.0 145.0 118.0 90.0 145.0 188.0 114.0 114.0 90.0 125.0 105.0 126.0 135.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.2434707792509911 0.006656727227605034 0.01478219854101616 GO:0051641 cellular localization biological_process 26.60484973365685 26.952620789810286 26.483270481781826 27.345961839153016 26.279255601518283 25.4185778179326 26.958241254376613 26.672073342895608 26.092823105217814 26.718897989751266 26.9717389998767 27.14146000688888 27.073340361583405 27.30161189280953 26.854096763293448 26.781363079558467 25.63306746005135 26.12725078184412 26.289021865922127 27.694760242854038 25.568098556053556 26.682037304581552 26.26268209934106 26.888421443559274 27.494471730975324 27.37862557173544 97.0 85.0 90.0 77.0 91.0 86.0 85.0 123.0 114.0 141.0 123.0 96.0 106.0 110.0 85.0 107.0 146.0 132.0 81.0 105.0 91.0 106.0 117.0 154.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 3.0 3.0 -0.3477710561534373 0.18420928818665294 0.2488021554728819 GO:0051704 multi-organism process biological_process 25.843676197068767 26.041896521476264 25.361487347197965 25.74570379359823 23.63054827094389 23.44526725180171 26.13417633253929 26.246317225486962 26.232861059110213 26.35984148482022 27.14135470726245 27.315452384150657 26.059024910107127 26.680350303374855 23.338568928447128 23.24050601728758 26.29447697838157 26.046169110799518 26.20032524383932 27.012376957066625 23.2382792308052 21.247704501437187 24.342748165684988 25.294534174445964 26.499361088635965 25.905250831186372 28.0 34.0 26.0 27.0 31.0 67.0 146.0 36.0 29.0 70.0 53.0 62.0 14.0 49.0 24.0 46.0 45.0 32.0 27.0 6.0 10.0 66.0 27.0 26.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 4.0 3.0 2.0 3.0 3.0 4.0 4.0 4.0 3.0 4.0 2.0 3.0 2.0 2.0 -0.19822032440749737 0.8624902301359216 0.8917877441670506 GO:0051707 response to other organism biological_process 21.72323670778597 20.82242733926768 17.5973256134569 20.990058156891124 NA NA 20.2985105503726 NA 23.840516628055482 NA 16.288235946851096 20.92493427020617 22.400875231560192 21.773424549769867 20.768345707611736 18.91530920884669 NA 18.90519727516316 NA 19.35997531919379 18.296092461171643 NA NA 21.804775758868352 NA NA 4.0 4.0 NA NA 6.0 NA 57.0 NA 2.0 6.0 20.0 8.0 10.0 4.0 NA 2.0 NA 4.0 4.0 NA NA 10.0 NA NA 2.0 2.0 NA NA 2.0 NA 2.0 NA 2.0 2.0 5.0 3.0 2.0 2.0 NA 2.0 NA 3.0 2.0 NA NA 3.0 NA NA 0.9008093685182885 0.5652987983097892 0.636726444305611 GO:0051715 cytolysis in other organism biological_process 23.079085749227254 23.223808635701232 22.626664293860426 22.97722991137997 18.111803098354727 19.913283609630216 23.3009817178623 22.983617999985928 22.70548231703476 23.53785896619175 24.359840495163002 24.435689771366267 22.98539852256832 23.86736298106142 NA 20.308201346282086 23.50525798992464 22.74396471124661 23.14989193155289 24.03933277673812 19.05808151610553 NA NA 22.221027792494016 23.64151282738551 23.193718691006133 3.0 3.0 3.0 3.0 3.0 7.0 3.0 3.0 3.0 6.0 3.0 3.0 NA 6.0 3.0 6.0 3.0 3.0 3.0 NA NA 6.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 NA NA 2.0 2.0 2.0 -0.14472288647397846 0.72477122130619 0.7743276961229171 GO:0051716 cellular response to stimulus biological_process 26.49373527583229 26.63695691253601 26.25476864723012 26.56631566259995 26.10043221139924 26.928479582613967 26.10355156282643 26.372075581900702 26.11748948799941 26.18216790019475 26.657834594057107 26.919081395680355 26.598742948675607 26.754434424067988 26.289022313737274 26.421017178652228 25.83331610977745 26.38714383073707 26.86633791097025 26.83127119835009 27.59627881559545 26.103491247320786 26.0618207307476 26.924293230612392 26.461827316653146 26.904433416804643 121.0 124.0 123.0 182.0 119.0 153.0 176.0 132.0 214.0 187.0 218.0 227.0 129.0 198.0 109.0 169.0 204.0 186.0 120.0 100.0 152.0 237.0 227.0 162.0 3.0 3.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 2.0 -0.14322163670372134 0.0940685547103812 0.1379524750629327 GO:0051745 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity molecular_function 25.95913653752425 26.077200905600968 25.294328040924484 NA NA NA 25.45010545005664 25.840350878674368 26.528512819773606 27.095807105219148 25.77766756435813 26.58083608349616 26.331750859652978 25.211909597694568 26.309898878666488 24.782173770778552 25.541834739582015 25.88651049212447 26.003656558587817 26.12277258041416 25.74750137201718 25.238444037685305 26.452834557706513 25.61279504491206 25.40092692361866 26.717844620896226 15.0 NA NA NA 23.0 21.0 39.0 23.0 26.0 20.0 27.0 15.0 30.0 17.0 26.0 19.0 26.0 28.0 20.0 19.0 31.0 19.0 25.0 19.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.11806436807671616 0.9438610611705001 0.9577970205788449 GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction biological_process 23.896163884925052 23.993632089949894 23.363629888026622 23.714195505546176 18.848768692520927 20.650249203796424 24.037947312028518 23.706111762489954 24.241357260763145 24.274824560357967 25.09680608932921 25.31186576627358 23.722364116734518 24.62923001460228 NA 21.04516694044829 24.242223584090837 23.480930305412826 23.886857525719105 24.77629837090432 19.795047110271746 NA NA 22.95799338666023 24.37847842155172 23.93068428517233 5.0 5.0 5.0 5.0 5.0 10.0 37.0 5.0 5.0 16.0 5.0 11.0 NA 10.0 5.0 10.0 5.0 5.0 5.0 NA NA 10.0 5.0 5.0 2.0 2.0 2.0 2.0 2.0 2.0 5.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 NA NA 2.0 2.0 2.0 -0.09746820502484255 0.9438610611705001 0.9577970205788449 GO:0051818 disruption of cells of other organism involved in symbiotic interaction biological_process 23.49412324850609 23.659060062088518 23.04170179313927 23.392267410658807 18.526840597633566 20.32832110890906 23.716019217141145 23.384183667602592 23.12051981631361 23.9528964654706 24.77487799444185 24.939294792279448 23.400436021847163 24.298014175105518 NA 20.723238845560925 23.920295489203475 23.15900221052546 23.564929430831732 24.45437027601696 19.473119015384377 NA NA 22.636065291772862 24.056550326664357 23.608756190284968 4.0 4.0 4.0 4.0 4.0 8.0 4.0 4.0 4.0 11.0 4.0 7.0 NA 8.0 4.0 8.0 4.0 4.0 4.0 NA NA 8.0 4.0 4.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 NA NA 2.0 2.0 2.0 -0.16493681358242895 0.72477122130619 0.7743276961229171 GO:0051883 killing of cells in other organism involved in symbiotic interaction biological_process 23.079085749227254 23.232215582566106 22.626664293860426 22.97722991137997 18.111803098354727 19.913283609630216 23.3009817178623 22.969146168323746 22.70548231703476 23.53785896619175 24.359840495163002 24.47572579644464 22.98539852256832 23.87432327102279 NA 20.308201346282086 23.50525798992464 22.74396471124661 23.14989193155289 24.03933277673812 19.05808151610553 NA NA 22.221027792494016 23.64151282738551 23.193718691006133 3.0 3.0 3.0 3.0 3.0 6.0 3.0 3.0 3.0 7.0 3.0 4.0 NA 6.0 3.0 6.0 3.0 3.0 3.0 NA NA 6.0 3.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 2.0 NA NA 2.0 2.0 2.0 -0.153129833338852 0.72477122130619 0.7743276961229171 GO:0051991 UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity molecular_function 19.982290946777663 20.511796886802173 NA 20.094474714194746 16.931771518517294 20.681278510266498 19.81715252943116 18.823855753818787 21.738669011401615 19.94220592809853 20.121322598562426 18.11476550669465 17.333316979512652 20.404808324959973 NA 22.232091916449367 18.982631571454547 20.5236015840284 19.445524955018282 19.54463745952318 18.425493731618033 19.938646584471297 20.79528516265424 21.635761449104194 20.069318323310128 19.028263615590085 NA 5.0 2.0 10.0 3.0 3.0 8.0 4.0 3.0 2.0 1.0 3.0 NA 12.0 2.0 6.0 3.0 5.0 3.0 5.0 4.0 11.0 4.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5295059400245101 0.29142131954205963 0.36699677778858775 GO:0052591 sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity molecular_function 23.860539535256024 21.91088885902903 18.50986328869548 NA 16.774420928706398 NA 22.06082360009311 19.24182253838257 21.835092381340537 NA 24.10083692667301 22.994977980953927 24.656805794383203 NA 22.208844539099488 NA 21.837311051268298 20.97687715421013 26.18880522424867 21.415682885431238 24.53052803500794 NA 23.943255531929086 NA 22.029593864602347 22.486078994622158 4.0 NA 2.0 NA 15.0 3.0 9.0 NA 18.0 17.0 13.0 NA 10.0 NA 12.0 4.0 36.0 11.0 16.0 NA 16.0 NA 15.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.9496506762269945 0.29184054514378843 0.3671542342131532 GO:0052654 L-leucine transaminase activity molecular_function 19.671562780419592 21.314132473597816 18.975995981171568 19.485675152000564 19.014991684041867 20.285054959061817 18.392637989134244 21.08484008738929 18.546328169015784 21.07790796616603 19.382256595092027 21.53343622202599 20.899125870852355 21.21404869171571 18.815492774227 20.925406164583922 19.508698620348888 21.091944880907075 18.89127123979333 21.35642702423105 20.70891243081649 20.864221052458404 20.25582604261737 23.208623225515986 19.85797604134433 19.707789714183143 3.0 1.0 2.0 1.0 1.0 3.0 1.0 5.0 3.0 4.0 4.0 1.0 2.0 2.0 3.0 5.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.642569693178224 0.0005320055051392492 0.0019244720881558927 GO:0052655 L-valine transaminase activity molecular_function 19.671562780419592 21.314132473597816 18.975995981171568 19.485675152000564 19.014991684041867 20.285054959061817 18.392637989134244 21.08484008738929 18.546328169015784 21.07790796616603 19.382256595092027 21.53343622202599 20.899125870852355 21.21404869171571 18.815492774227 20.925406164583922 19.508698620348888 21.091944880907075 18.89127123979333 21.35642702423105 20.70891243081649 20.864221052458404 20.25582604261737 23.208623225515986 19.85797604134433 19.707789714183143 3.0 1.0 2.0 1.0 1.0 3.0 1.0 5.0 3.0 4.0 4.0 1.0 2.0 2.0 3.0 5.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.642569693178224 0.0005320055051392492 0.0019244720881558927 GO:0052656 L-isoleucine transaminase activity molecular_function 19.671562780419592 21.314132473597816 18.975995981171568 19.485675152000564 19.014991684041867 20.285054959061817 18.392637989134244 21.08484008738929 18.546328169015784 21.07790796616603 19.382256595092027 21.53343622202599 20.899125870852355 21.21404869171571 18.815492774227 20.925406164583922 19.508698620348888 21.091944880907075 18.89127123979333 21.35642702423105 20.70891243081649 20.864221052458404 20.25582604261737 23.208623225515986 19.85797604134433 19.707789714183143 3.0 1.0 2.0 1.0 1.0 3.0 1.0 5.0 3.0 4.0 4.0 1.0 2.0 2.0 3.0 5.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.642569693178224 0.0005320055051392492 0.0019244720881558927 GO:0052657 guanine phosphoribosyltransferase activity molecular_function 21.09363411663632 23.695639925696238 22.72922183250599 23.97139174238552 20.77202212696804 21.473697648467173 20.513749210014392 24.187540625685592 19.74695626488849 23.695948080489256 20.290306848014573 23.01678787089239 20.67080348749221 24.21761125167693 21.99474658662712 23.261461397687945 20.7276146742918 22.970604207392487 21.46587129275348 23.83790904526123 20.68324536984974 23.083285608081752 20.010169419096844 24.813868847012877 20.22952445478365 23.4342197075422 6.0 13.0 3.0 4.0 5.0 12.0 4.0 13.0 5.0 11.0 3.0 10.0 7.0 11.0 6.0 11.0 11.0 14.0 4.0 8.0 4.0 12.0 3.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.602005809059918 5.312128159411724e-05 0.0005099643033035255 GO:0052689 carboxylic ester hydrolase activity molecular_function 25.90210929944307 26.680924679154963 25.492687506747984 26.175814886106053 25.30850465348889 26.84884171744911 25.74706828524492 26.59633228620093 26.415356985788478 26.196177847262568 26.206705299050327 26.67602845314493 26.202205668004908 26.789299118818665 26.666713909213208 27.480090713036308 24.901905370281682 26.312155982520746 25.879731950547352 26.50084891769875 24.879552525676488 26.326428279882737 25.954816508890524 27.153660419089483 26.01291207981625 26.48429027506967 69.0 77.0 71.0 106.0 104.0 116.0 111.0 104.0 111.0 109.0 125.0 99.0 108.0 121.0 83.0 123.0 144.0 118.0 79.0 102.0 113.0 118.0 123.0 115.0 4.0 5.0 3.0 3.0 4.0 4.0 1.0 3.0 2.0 6.0 3.0 6.0 3.0 4.0 2.0 5.0 3.0 5.0 2.0 5.0 3.0 3.0 5.0 3.0 -0.7788153797118937 0.0009986863791802587 0.0031633517797384847 GO:0052803 imidazole-containing compound metabolic process biological_process 28.800014103968838 26.31924662505764 27.640992235882496 26.33158369287141 27.193718689212922 23.9159768561502 28.576449738517386 26.615020419672465 29.191456251035447 25.588950108464168 29.27544586667933 26.96072728142512 28.978851536240875 25.42402110191145 29.14581695145317 24.273342169793853 28.26803523967123 21.582009251892813 28.48108861262452 28.45063638140892 26.764582084073297 26.701657513956928 29.897305247303315 21.42346941671312 29.270624826549202 26.12873393069193 52.0 45.0 72.0 42.0 118.0 71.0 191.0 64.0 196.0 64.0 183.0 45.0 195.0 42.0 122.0 17.0 143.0 174.0 95.0 62.0 141.0 8.0 169.0 60.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.480767478911197 0.00010962068302139599 0.000648372570666835 GO:0052908 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity molecular_function 19.223929272275 22.0907482305654 20.782854803902712 21.134666107680555 19.34284256911527 21.633662420419093 18.704318067088163 22.04499830113958 17.348388273787595 22.01789827530846 19.78949907538181 20.984831458170575 19.062232113303267 22.585572093022233 18.442708972716307 21.639266868307647 NA 21.363060691652347 19.41614621959386 22.53202005257901 16.60095257601721 21.07765342614003 17.927884368030828 23.493692385933212 19.63507876058669 22.266989987109334 4.0 7.0 2.0 5.0 1.0 8.0 1.0 7.0 4.0 7.0 3.0 6.0 2.0 6.0 NA 8.0 4.0 8.0 1.0 5.0 2.0 16.0 5.0 8.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.8668189582903985 4.865007418510381e-05 0.0005099643033035255 GO:0055065 metal ion homeostasis biological_process 27.57222958157689 27.73706339191659 26.15785224270638 28.62119550646373 27.87568461974294 28.074525167177356 28.896287835849265 26.50686221407281 26.913539220778212 27.13720483014127 25.09090639610218 23.95974132589136 28.643105574739128 28.283980395161425 26.808483757443717 28.122233833659845 26.450564926578302 26.805098529176732 27.046193358896346 28.8257679774772 26.489200876019698 28.264090607830052 28.64487688398973 25.133294554964703 26.962856950390893 27.239685932731625 22.0 12.0 6.0 15.0 28.0 27.0 22.0 17.0 23.0 15.0 15.0 24.0 18.0 16.0 18.0 18.0 18.0 23.0 16.0 15.0 26.0 15.0 25.0 21.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.16483381033969735 0.6033317722918665 0.6716842567531217 GO:0055076 transition metal ion homeostasis biological_process 26.995851255153237 27.153023566456557 25.574726653475714 28.03623300574257 27.290722119021783 27.489562666456198 28.31424626167784 25.921899713351657 26.350392546556915 26.55262547193622 24.60042308617369 23.43100826388904 28.06090658766597 27.700081968813954 26.234057471296392 27.537411017573053 25.88492344507952 26.22013602845557 26.462827194982623 28.241039671867064 25.92197198374343 27.679128107108887 28.068937850808855 24.54833205424355 26.399620560804124 26.660928718107748 15.0 8.0 4.0 10.0 20.0 18.0 19.0 12.0 20.0 12.0 12.0 17.0 14.0 11.0 14.0 12.0 13.0 16.0 13.0 10.0 21.0 10.0 21.0 16.0 4.0 3.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 2.0 -0.1571723113033201 0.6861059569955559 0.7413508522341591 GO:0055080 cation homeostasis biological_process 27.98295576366846 28.1516393321842 26.571970408426992 29.03623300574257 28.290722119021783 28.489562666456198 29.30986265118025 26.921899713351657 27.317543837933478 27.55205071999802 25.45627799358677 24.34582032852836 29.05675932956676 28.698485562801565 27.218224152913585 28.537201485549478 26.85584400946108 27.22013602845557 27.46043202690466 29.240688364942503 26.89528915243421 28.679128107108887 29.055381396580554 25.54833205424355 27.366907456152806 27.65161075141539 29.0 16.0 8.0 20.0 36.0 36.0 25.0 22.0 26.0 18.0 18.0 31.0 22.0 21.0 22.0 24.0 23.0 30.0 19.0 20.0 31.0 20.0 29.0 26.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.16868356851573907 0.5637028616507731 0.6360770084449954 GO:0055085 transmembrane transport biological_process 28.74632369432097 29.553163199232827 28.59554536986713 29.18307817151152 28.644978480747266 29.27043375252255 28.271361539451505 29.529151736914304 28.66192749487617 29.457840250531426 28.763769898187984 29.60792495572441 28.901816838067198 29.27451255888608 28.544871741843988 29.930373931619183 28.372615323323576 29.735907590907587 29.228977951037326 29.701946235496262 29.104938078508557 29.42076937358561 28.757053071951656 29.63134538354679 28.81670926417083 29.705172575278834 336.0 324.0 330.0 378.0 315.0 411.0 370.0 437.0 372.0 424.0 415.0 341.0 389.0 407.0 277.0 399.0 437.0 490.0 384.0 391.0 368.0 349.0 399.0 499.0 4.0 4.0 5.0 4.0 7.0 4.0 7.0 5.0 7.0 6.0 7.0 5.0 7.0 4.0 5.0 5.0 9.0 7.0 6.0 4.0 7.0 5.0 6.0 5.0 -0.8068395049118564 4.146041132679973e-05 0.0005099643033035255 GO:0055086 nucleobase-containing small molecule metabolic process biological_process 34.60662410934426 35.436749598401796 34.816044899558875 34.80847592651589 34.47513832689583 35.387149045594 34.21310672091081 35.61010911720659 34.09666607104483 35.34331447271864 34.737780942894084 35.31915209693781 34.710272780009554 34.96852458611239 35.02959817067098 35.80999840630175 34.161690238747376 35.88638069224174 35.17151963730299 35.6105852932722 34.583069502673304 35.31694642361043 34.28279513558569 35.517668847223064 34.548290698967854 35.301140864296435 12674.0 12581.0 12645.0 15466.0 13843.0 20265.0 15519.0 18721.0 15927.0 18598.0 17380.0 14162.0 17385.0 18830.0 13869.0 19365.0 21404.0 20532.0 16281.0 16208.0 16469.0 17286.0 16674.0 19086.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 7.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 -0.8301254890575365 0.00010962068302139599 0.000648372570666835 GO:0055114 oxidation-reduction process biological_process 29.49420934864614 28.78839392600093 28.689185005795803 27.92905544858388 28.512164461450343 28.17931294315983 29.17023003837512 28.92574302060248 29.81192693696214 29.374056024668523 29.743886914749588 28.70260551741841 30.000651448619646 28.316455999989767 29.919265170346986 28.629068033650324 29.61298713909008 28.551411065500353 29.016049111189265 29.29107892450355 29.525167385635577 28.92187243136425 29.463944454464087 27.77907103699448 29.656959458253997 29.616035544354983 95.0 38.0 49.0 58.0 204.0 112.0 229.0 119.0 237.0 124.0 207.0 65.0 260.0 93.0 175.0 107.0 272.0 151.0 185.0 110.0 215.0 74.0 226.0 149.0 2.0 2.0 1.0 4.0 5.0 3.0 4.0 3.0 4.0 4.0 5.0 2.0 4.0 2.0 4.0 3.0 7.0 3.0 3.0 3.0 5.0 4.0 4.0 5.0 0.7058154226452125 0.004669131805023211 0.010994483948432015 GO:0055129 L-proline biosynthetic process biological_process 20.771781254337913 20.39589495534456 17.38632439943357 18.95377187854764 22.68764120196969 20.882625240634727 19.172277806741857 20.13843033417906 15.101140225083896 18.93022909447416 18.604244096464907 21.225581876541817 20.666220105444147 21.879313398226234 NA 20.536922857009472 18.431159657804024 18.942383713327285 22.20962692644269 19.99833758355766 20.262049405869654 19.246072364396586 21.702971244226585 20.66216324915545 17.63227060095765 19.60588823269657 1.0 2.0 11.0 9.0 4.0 5.0 1.0 3.0 3.0 10.0 7.0 11.0 NA 7.0 3.0 3.0 15.0 7.0 6.0 2.0 11.0 10.0 3.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.375886298993354 0.46018093544712035 0.5412872831649446 GO:0060255 regulation of macromolecule metabolic process biological_process 30.00544496697305 30.66515583327186 30.09644612167587 30.278425254459624 30.200595893018914 30.545127990094123 29.602807273897014 30.92162705333425 29.83221368901473 30.86448055786673 29.99514148087605 30.78911045072586 30.05621350740126 30.507812858968247 29.994598719742452 30.576621454114328 29.369076301175657 30.558223020462915 30.50441297093873 31.10554442429684 30.17643511625987 30.377817786010297 29.855749390892147 30.493305010874057 30.064391144712328 30.73930359443136 778.0 870.0 741.0 902.0 845.0 1199.0 959.0 1232.0 1108.0 1136.0 1114.0 978.0 910.0 1114.0 719.0 1167.0 1490.0 1372.0 969.0 852.0 876.0 1150.0 1115.0 1292.0 6.0 6.0 6.0 6.0 7.0 7.0 8.0 8.0 8.0 8.0 8.0 7.0 8.0 7.0 7.0 6.0 7.0 7.0 7.0 6.0 7.0 7.0 7.0 7.0 -0.6597108662988092 6.784570247173055e-05 0.0005498145239267514 GO:0061783 peptidoglycan muralytic activity molecular_function 20.547501089777764 22.77701236681783 22.08809065175008 22.857581891795263 21.747732067456077 23.46072517988473 19.4873106891608 23.258053874095804 18.951987041376096 22.158927350212522 19.811788505240926 24.114449602689948 20.821601749228392 21.66513147552279 18.920317770489106 23.064779749909572 20.244572231242703 23.493543353583828 20.930926808348488 21.873221643795734 20.05867881793441 19.495228142168163 17.503217447394974 21.400154849590464 20.395945294059988 21.501104100260854 13.0 17.0 9.0 15.0 3.0 25.0 2.0 12.0 4.0 18.0 5.0 8.0 3.0 19.0 4.0 19.0 7.0 11.0 4.0 5.0 1.0 8.0 6.0 7.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 1.0 3.0 2.0 3.0 1.0 3.0 2.0 3.0 -2.2295112770400642 0.0009986863791802587 0.0031633517797384847 GO:0065003 protein-containing complex assembly biological_process 26.620297663229014 27.31718534722681 26.761129078692537 26.761634179330386 26.373194223080247 26.72835565077273 25.37962638778398 27.454826293820247 26.40884482554689 27.36051630195487 26.485681294711107 27.547823444864946 26.86273999818476 27.282799755591586 27.121297991905546 27.612369122576013 26.197219507538605 27.407127358466497 26.785193026818018 27.65675494985495 26.77720548538661 26.83399894010168 27.36975643943195 27.605067528410917 25.873577703615066 27.1349463264328 60.0 28.0 44.0 70.0 40.0 67.0 52.0 52.0 81.0 77.0 71.0 57.0 78.0 77.0 58.0 90.0 85.0 72.0 69.0 43.0 79.0 69.0 46.0 51.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.6968876839977973 0.0014961642897455532 0.004424675435076897 GO:0065007 biological regulation biological_process 32.496798209633695 33.08294614745828 32.449566329953605 32.84771629082648 32.6762056367079 32.989875200637954 32.44438077080002 33.246507863756584 32.29077782717515 33.224003223492915 32.408629893197386 33.08522644965121 32.716347323993936 33.033352373465945 32.382510592793544 33.026623243748354 31.82072786358483 32.92955891420033 32.89975911884984 33.59225512938363 32.56379459362811 32.85073845310439 32.56061299349667 32.89993273503092 32.49503009734853 33.09152451816959 4397.0 5037.0 4256.0 4967.0 4692.0 6992.0 5475.0 7245.0 6213.0 6484.0 6313.0 5625.0 4900.0 6425.0 4020.0 6767.0 7738.0 7903.0 5410.0 4934.0 5026.0 6735.0 6269.0 7423.0 2.0 2.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 2.0 3.0 3.0 3.0 2.0 2.0 3.0 3.0 2.0 3.0 -0.5861479378245846 5.312128159411724e-05 0.0005099643033035255 GO:0065008 regulation of biological quality biological_process 29.67826670843524 29.919360987312704 28.61083532860423 30.55480865923963 29.886482353580664 30.073862629878683 30.772949477306035 29.249844303401083 29.011200009603442 29.509801254631117 28.44619331863317 28.17944748956645 30.600775482084146 30.39918984041894 28.974751374513197 30.21562016160725 28.591208722013693 29.225651189084267 29.731334892615124 30.91304159241661 28.908889453473467 30.21877880559042 30.573352329324088 28.845336367031607 29.18894262806107 29.43515490717104 245.0 245.0 229.0 318.0 269.0 407.0 258.0 389.0 289.0 338.0 284.0 324.0 269.0 343.0 225.0 364.0 411.0 448.0 305.0 274.0 292.0 370.0 272.0 320.0 6.0 6.0 7.0 6.0 6.0 6.0 7.0 6.0 7.0 6.0 7.0 6.0 8.0 6.0 7.0 6.0 8.0 7.0 5.0 5.0 7.0 6.0 6.0 6.0 -0.24109427887746548 0.3556110610952391 0.43337630976650365 GO:0065009 regulation of molecular function biological_process 23.29102388466908 22.592297242474466 NA NA NA 15.256093142867355 20.260683610237805 18.39711229861413 24.21088721612757 23.205809411057864 21.345893468214122 25.202645974438425 24.846182465506445 22.425045932748127 23.72767444429852 NA NA 19.0644583281158 19.98270039841432 16.09472437554814 NA NA 21.704218626111523 19.910952727360204 NA 19.9351083829504 NA NA NA 2.0 2.0 6.0 10.0 16.0 6.0 16.0 12.0 4.0 6.0 NA NA 6.0 4.0 6.0 NA NA 10.0 6.0 NA 4.0 NA NA NA 1.0 1.0 2.0 3.0 3.0 2.0 3.0 3.0 2.0 2.0 NA NA 2.0 1.0 2.0 NA NA 2.0 2.0 NA 2.0 0.6987266421946146 0.0807162584311211 0.12314656543036569 GO:0070006 metalloaminopeptidase activity molecular_function 22.603047156933755 22.69946557999792 18.318570678609266 21.098017847652702 20.770671198333307 23.41167587866983 22.556581258134194 22.676893360779136 23.95194541879625 22.01798539560425 23.579724889768897 21.992909532357068 23.301322330347862 21.47232280761568 22.190090178535446 23.717271145008613 21.963227989653273 23.49511112613481 21.0683444034488 22.82160857841732 21.37256173904964 22.339188931807133 22.56443533232125 22.861750228060657 23.11311666005578 22.049018346438345 2.0 6.0 3.0 11.0 10.0 14.0 16.0 11.0 15.0 12.0 16.0 7.0 11.0 18.0 9.0 14.0 9.0 15.0 9.0 12.0 16.0 11.0 11.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.09641842306416493 0.5253727863737021 0.6008633207515945 GO:0070011 peptidase activity, acting on L-amino acid peptides molecular_function 28.24512491600432 28.77550771529193 29.134248963095413 28.28554147832912 28.24978571343725 28.382453408905924 27.488885954626426 28.76156665198577 28.39520752544709 28.450292375074323 28.36402168626373 28.95228361767782 28.08659328409379 28.587862870838546 28.18436761584055 28.994034661676906 27.65078654618889 29.34381070408695 28.74692591243041 28.91926458796496 27.57290552411231 28.392836125208078 27.89447479889033 29.316512397786184 28.262820743151302 28.372698716260533 279.0 285.0 300.0 418.0 231.0 424.0 303.0 406.0 305.0 392.0 323.0 344.0 358.0 489.0 230.0 543.0 475.0 474.0 223.0 367.0 278.0 503.0 299.0 452.0 6.0 5.0 5.0 6.0 6.0 6.0 6.0 6.0 7.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 8.0 6.0 6.0 5.0 6.0 6.0 6.0 6.0 -0.5303827992876116 0.0032349119169146935 0.007931571851295751 GO:0070013 intracellular organelle lumen cellular_component 22.093217322168808 23.809777669155537 22.79657123970253 24.468748775707674 19.722702403694235 20.858631845972454 19.77850068504996 23.834519256462816 22.62625931138753 23.511082046227013 21.984743805687675 24.12386463681857 21.33402758006532 24.09247158523557 22.157604808674645 23.356198091371056 21.429075260665485 23.089586628768863 22.416456578724627 24.67701609920877 NA 22.99082990017878 22.55722436334703 23.42815729600905 22.86277952761924 24.40042396234428 3.0 4.0 2.0 2.0 5.0 4.0 5.0 3.0 4.0 9.0 6.0 4.0 4.0 3.0 3.0 5.0 5.0 3.0 NA 2.0 3.0 6.0 3.0 3.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 3.0 3.0 4.0 5.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 -1.7165603469867285 0.00045130665609211163 0.0017224180636176002 GO:0070040 rRNA (adenine-C2-)-methyltransferase activity molecular_function 21.65811953462421 21.89533011974732 23.340915406941928 20.2235471462838 22.33461511105927 22.152491262152033 15.68090807351053 22.06303583665921 NA 20.82671587344869 20.19307840833889 22.836338580165553 21.762264484697155 20.8262378434125 22.83133662087501 23.163135808599442 19.72808107721201 21.38017737682952 20.32205453715 21.909435217694202 22.232483899451164 22.18284941215175 15.47974310991622 20.766481121666914 20.022377874667608 21.37902416038832 7.0 4.0 9.0 13.0 1.0 9.0 NA 6.0 3.0 12.0 5.0 3.0 5.0 15.0 2.0 7.0 5.0 9.0 7.0 6.0 1.0 7.0 5.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.23721058512311188 0.2954328504393152 0.3712893923124729 GO:0070043 rRNA (guanine-N7-)-methyltransferase activity molecular_function 18.805638921998472 20.982280444524864 17.751806962971926 20.246507941212364 19.295104808877216 20.225629947097982 18.230993567593387 20.216055328004586 19.76359558809481 20.26640296763684 19.793800362291968 19.802163663019897 18.584453312814762 20.83306025635348 NA 20.166671400264427 17.221873266591867 20.53419183883392 18.385560931840576 22.943063357958998 19.20247879068723 20.439649231473158 16.47380317507976 21.821765353324256 18.893262294474727 20.240377567775678 1.0 4.0 1.0 5.0 2.0 5.0 1.0 4.0 4.0 4.0 3.0 4.0 NA 6.0 2.0 8.0 4.0 7.0 5.0 4.0 2.0 8.0 3.0 2.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.176641522526392 4.865007418510381e-05 0.0005099643033035255 GO:0070062 extracellular exosome cellular_component 20.54288411315056 20.068705212474143 19.151519743716268 19.65686904590007 19.086236046215614 20.90710279719563 NA 19.940603404863968 19.27125512533839 NA 22.66373899163034 19.7101289892301 20.61034575963044 20.30371049874706 19.726208762053695 20.64308412774261 21.04039628673453 18.963166185639288 19.014510884390265 19.60781951431197 18.00603587084595 NA 21.41360493522225 19.92960630029664 17.43245593157638 NA 2.0 3.0 2.0 3.0 NA 3.0 3.0 NA 6.0 4.0 3.0 2.0 2.0 5.0 5.0 3.0 2.0 2.0 1.0 NA 3.0 2.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.4741789006764172 0.5688114004133373 0.6401051647572994 GO:0070063 RNA polymerase binding molecular_function 21.39275721109755 21.982442645865564 20.733037138051195 19.215061079329907 20.743795222640003 18.212921915802703 NA 22.15678158522145 18.634484882877064 23.20025254634062 21.744147273636226 22.988100606245432 22.10838749941439 22.341934855406127 NA 21.644387286128516 20.43561605663009 21.95214406203958 23.343054092668236 22.25502789250482 20.777250076521554 20.853398747906727 18.91100725398637 19.885690684449106 20.247549303109867 22.431651152904855 4.0 1.0 1.0 2.0 NA 4.0 2.0 6.0 6.0 5.0 5.0 6.0 NA 4.0 3.0 5.0 10.0 5.0 3.0 2.0 3.0 4.0 4.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5896854347680147 0.1872490441233765 0.25263438601726906 GO:0070084 protein initiator methionine removal biological_process 20.142841561539328 22.68552150211863 18.318570678609266 21.098017847652702 20.770671198333307 23.41167587866983 19.7716982424602 22.676893360779136 19.869860238880147 22.01798539560425 20.771377231694267 21.992909532357068 20.94182135079123 21.47232280761568 19.997312740715675 23.717271145008613 17.81563283496833 23.49511112613481 19.764881582727803 22.659866733226 21.34019189376137 22.339188931807133 19.00734616356845 22.861750228060657 19.55325489372534 22.049018346438345 2.0 6.0 3.0 11.0 4.0 14.0 3.0 11.0 6.0 12.0 8.0 7.0 5.0 18.0 3.0 14.0 4.0 12.0 8.0 12.0 4.0 11.0 4.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.5426799405793012 4.146041132679973e-05 0.0005099643033035255 GO:0070180 large ribosomal subunit rRNA binding molecular_function 27.419092570738112 27.94823362818003 27.47694071429265 27.45288730295561 27.433371478823496 28.08507557863265 27.155777748559057 27.818208131565466 27.60976039590005 27.222002157067127 27.5698883785037 28.2480206026782 27.14847012350112 28.09189909868216 27.637636227532678 28.30910754453544 27.06954080871121 27.677972786723128 27.74805636144854 27.939137355207237 27.48854799877255 28.088985149081235 27.426822298534827 28.15888164733932 27.053861909025827 27.90484163757645 29.0 19.0 35.0 46.0 36.0 35.0 55.0 29.0 48.0 33.0 38.0 29.0 54.0 33.0 40.0 41.0 53.0 53.0 35.0 28.0 46.0 35.0 36.0 37.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5291410574419189 0.0009986863791802587 0.0031633517797384847 GO:0070181 small ribosomal subunit rRNA binding molecular_function 21.498408152397623 23.156563793536865 22.808063017242368 22.54081006566485 22.1276009150129 23.354251389769807 19.579306270144052 23.48037208754212 20.551425623507036 22.95386640755419 21.395241244781342 23.13600122085009 21.26548775925512 22.89510676360169 21.726899994411134 23.450035853721577 21.127973410992986 22.248945448546923 21.37419369947875 23.166887682195977 21.48665783106017 23.054698613811752 21.155887328887573 23.909778748978265 21.114262119471565 22.966719248457608 14.0 15.0 12.0 15.0 4.0 18.0 4.0 14.0 8.0 15.0 9.0 14.0 8.0 17.0 6.0 14.0 7.0 15.0 13.0 15.0 4.0 16.0 9.0 20.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.658155641139242 5.312128159411724e-05 0.0005099643033035255 GO:0070395 lipoteichoic acid biosynthetic process biological_process 21.36370518723586 24.418096520301237 23.246497392600194 24.241792472364892 22.60150054682818 24.89305771117243 19.960203096262322 25.129450259444734 18.843086778671857 24.08675329264452 18.421805252354066 23.50264913814271 21.12344555064817 24.640938694761672 20.20759109633372 24.77264965518981 19.84586857787286 24.06677102798725 20.77897743827176 24.641329673325767 21.11075401443929 24.25714829994723 NA 23.96461163812554 21.528298235416468 23.98621159556657 12.0 17.0 8.0 14.0 4.0 21.0 2.0 13.0 2.0 13.0 3.0 16.0 4.0 16.0 2.0 16.0 5.0 15.0 4.0 15.0 NA 17.0 5.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -3.0543913330653787 4.865007418510381e-05 0.0005099643033035255 GO:0070475 rRNA base methylation biological_process 21.70524237452248 22.21581354437207 23.288461834466208 21.263005645367887 22.125130497267293 22.36655289550777 17.997265963230895 22.279721505826192 NA 21.02939558447673 20.575055639071547 22.89497933073536 21.825200435828386 21.464676769973575 22.9144986439079 23.53348235418797 19.72808107721201 21.737961600127722 20.88197660849349 22.01607585149748 22.26415318107693 22.150965288337 16.6886591409822 22.156453642247982 20.420107949721416 21.693139522720035 7.0 11.0 8.0 15.0 2.0 12.0 NA 9.0 6.0 16.0 8.0 8.0 6.0 21.0 2.0 12.0 9.0 10.0 8.0 7.0 2.0 17.0 7.0 9.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.510571169849591 0.12389131916687696 0.17411752963993518 GO:0070566 adenylyltransferase activity molecular_function 23.84039381611135 23.385900086277122 24.29891092284512 23.132486578781872 24.21302098227933 23.15513285337368 23.56647386689005 23.557818314947486 23.152137265189854 23.040498522011145 23.75297893337193 23.404948530130433 23.67087884109205 23.409108274243692 23.949906624036718 23.81678111983518 23.21744140203611 22.77737138586383 23.620406517020346 23.13033487120836 24.022411676045085 23.771442803672485 23.329767936171965 23.932547470963467 24.545244591882806 22.98452864133512 15.0 18.0 17.0 13.0 20.0 18.0 18.0 19.0 27.0 20.0 25.0 17.0 28.0 22.0 18.0 19.0 37.0 19.0 23.0 14.0 26.0 25.0 36.0 18.0 3.0 4.0 2.0 5.0 5.0 4.0 5.0 4.0 6.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 4.0 4.0 4.0 5.0 5.0 6.0 3.0 0.45449372983422975 0.017926339076638688 0.03379466943753034 GO:0070567 cytidylyltransferase activity molecular_function 21.437953124792468 21.96646099611004 22.057910572194228 22.25259341344292 20.15637759338413 18.461334283420783 20.61081598458107 22.81408057517784 21.77735658958755 21.81789703575997 21.87432259163597 21.32226846279694 21.789619445221266 22.41490080362018 21.7827451108313 20.939340569125374 22.03878347808234 21.476601928810066 21.586617432695235 22.715523497826126 20.13194373631411 20.462016050759967 19.831345679539474 22.469827326351343 21.3877620793968 22.381137478355626 6.0 7.0 3.0 2.0 3.0 11.0 10.0 12.0 11.0 6.0 12.0 9.0 8.0 5.0 10.0 8.0 9.0 14.0 4.0 5.0 3.0 12.0 9.0 9.0 1.0 3.0 2.0 1.0 2.0 4.0 3.0 5.0 3.0 3.0 4.0 4.0 3.0 1.0 2.0 4.0 3.0 5.0 3.0 2.0 3.0 4.0 4.0 4.0 -0.5285078713175722 0.14891467317876572 0.20512749682902828 GO:0070569 uridylyltransferase activity molecular_function 24.567430807482534 24.095476639599394 24.515051833533462 23.374689589036745 22.55798708758736 24.171239890239946 24.961700414013986 24.153422512431106 22.94359576407206 23.858407157330056 24.57350659852202 24.33465403061977 24.27360582002936 24.2850839384917 23.53806853400895 24.26559505995431 23.991151774374426 23.452611642801113 22.821584108673118 24.52290997396722 25.859173210758648 23.819391781095966 25.618856048308817 24.70656528843373 24.99931223511044 23.50782008715757 20.0 11.0 13.0 19.0 13.0 19.0 19.0 20.0 19.0 18.0 18.0 16.0 20.0 20.0 13.0 17.0 14.0 23.0 19.0 16.0 20.0 17.0 22.0 22.0 3.0 2.0 2.0 2.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 3.0 0.4719541678831405 0.4529203011037244 0.5347630423627702 GO:0070626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity molecular_function 23.577953818045753 24.3647314165381 24.083763471167455 24.044778805791477 23.89428263050361 23.33122822639725 22.354839231712933 24.057195450723714 23.225447256040805 24.018940624115878 22.56302527266666 24.53559549281535 24.924833770296374 24.894021822710208 23.198432735962644 24.807369934344926 23.512041297781234 24.430162054464105 22.451265598958372 24.45537818222972 23.17940112345761 24.77760299490189 23.57939968481938 24.31511793184479 23.771100661164517 24.00381884493939 16.0 16.0 17.0 12.0 14.0 22.0 12.0 29.0 14.0 23.0 27.0 19.0 12.0 23.0 22.0 23.0 15.0 26.0 19.0 22.0 22.0 18.0 22.0 27.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.7867775984923462 0.0032349119169146935 0.007931571851295751 GO:0070677 rRNA (cytosine-2'-O-)-methyltransferase activity molecular_function 19.084505993626554 19.635810039832872 17.907227744393424 16.300106932898014 NA 19.793798663797702 18.83528003668958 19.423618731431308 18.64189406923416 18.693120145849733 20.577099081282828 19.10907184480968 19.472870509626308 19.807233036923357 19.434724918799066 20.692741836823107 17.829074524326977 14.881118420013385 NA NA 18.364813382678822 NA 18.041701063306586 21.391742521383385 19.18424877994717 16.103852297788563 1.0 2.0 NA 4.0 4.0 4.0 2.0 3.0 6.0 4.0 4.0 3.0 4.0 5.0 3.0 1.0 NA NA 2.0 NA 3.0 5.0 4.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.5513040462063188 0.6501474440948545 0.7123652416421232 GO:0070981 L-asparagine biosynthetic process biological_process 21.180167082478558 23.419309143812505 17.796568194369534 21.333005801971094 19.08951189492431 23.295694924279534 21.336176672865587 22.54696021967661 21.298803384992357 21.678879324415174 21.189117216734708 21.620091112736844 21.847594800329762 20.415968852874574 21.540096432577986 24.934853402846922 20.88894732101686 24.744378024438 19.890926657521167 21.134543348904653 21.085857365216 23.22181565527814 21.159671618912483 24.918442858161374 22.468634925293614 21.777820029395073 3.0 9.0 3.0 14.0 7.0 12.0 8.0 11.0 8.0 8.0 9.0 6.0 7.0 15.0 5.0 21.0 6.0 9.0 3.0 11.0 7.0 18.0 10.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -2.239142061333947 0.007911788680711459 0.016907384030013527 GO:0071103 DNA conformation change biological_process 28.42441125354661 28.676794999098266 28.329546693576894 27.87778234660426 27.71828121020501 28.051714192165882 28.243712264450984 28.43486840502851 27.789280885898656 28.861930213100123 27.95669096551225 28.94875901469017 28.36807962096664 28.603730289268398 29.333506919128734 29.262523078927412 27.70872967836243 28.544691356249018 27.985115317327466 28.558589376688534 29.55331492924172 28.84014745850831 28.689519798815304 28.905546587277797 27.750432481013465 28.6910537909924 38.0 35.0 35.0 41.0 46.0 33.0 46.0 35.0 63.0 52.0 61.0 61.0 40.0 58.0 32.0 34.0 66.0 58.0 51.0 33.0 58.0 55.0 59.0 65.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -0.25238374555165777 0.04964722965745621 0.07872902492059129 GO:0071265 L-methionine biosynthetic process biological_process 21.38568406070491 22.42938440031564 20.199192420440397 19.56236896292696 21.276961691718853 23.50159277132871 20.76932266408418 21.623921538202303 20.869983526861038 22.515962070811984 21.532074748924508 23.384550403452412 22.682271582284425 22.495206942844472 21.091519599848176 21.378986299785982 19.89999564231468 21.863527675097632 21.950326583311963 21.520774045153622 20.797517654280888 22.169893452575455 21.64309428833589 23.317287510434628 21.655941111648087 22.0406801598662 3.0 2.0 10.0 10.0 7.0 14.0 7.0 6.0 7.0 12.0 12.0 9.0 6.0 6.0 4.0 11.0 9.0 5.0 7.0 6.0 10.0 8.0 10.0 11.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.04370033961073 0.02092133533779403 0.038284203081476474 GO:0071267 L-methionine salvage biological_process 20.235173858674735 19.76903175189929 NA 18.198905103441547 19.797915632815037 19.654511080471345 20.08706105180004 20.048393163118813 19.635217000315546 19.82502054835905 19.276093047518327 21.332234876256017 20.767149655324666 17.982230656229675 20.472521703891594 NA 17.340313081260152 20.29113176328943 20.87678718846937 19.299402967196794 20.0665841681278 18.520658457814495 20.54078969219753 18.13074674060001 21.0342300720688 20.192386052709416 NA 1.0 7.0 5.0 5.0 3.0 4.0 1.0 3.0 7.0 7.0 2.0 3.0 NA 2.0 4.0 6.0 2.0 5.0 1.0 6.0 2.0 7.0 6.0 NA 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 1.0 NA 2.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 0.4661421067754432 0.17825971780582572 0.24313456592532298 GO:0071555 cell wall organization biological_process 23.73762366048903 25.57103468864987 25.130140891336413 25.20970576323421 24.055606537908073 25.2713125010958 22.44508420923243 25.866914234457912 23.023650140795045 25.284057171258567 23.4593708593637 25.68586421956984 24.135388286317593 26.200150814845976 24.059602152107463 25.685857160548142 23.17297773440608 24.81997423418913 22.927970300590008 25.55266617579513 23.458770875428534 25.229446247526692 23.187332159314327 26.28618600645457 23.6851973378132 24.920954229641882 36.0 48.0 30.0 59.0 21.0 75.0 19.0 64.0 32.0 59.0 46.0 66.0 44.0 93.0 25.0 65.0 33.0 63.0 35.0 62.0 29.0 79.0 39.0 71.0 NA NA NA NA NA NA NA NA NA NA NA NA 1.0 NA NA NA NA NA NA NA NA NA NA NA -1.833411028160839 5.312128159411724e-05 0.0005099643033035255 GO:0071616 acyl-CoA biosynthetic process biological_process 27.0908446726324 25.39660437290459 25.117643112283314 23.95711052369505 24.496704398598226 24.538948619104282 26.979853284171238 25.66498530975873 27.76617004766519 25.81984898467648 27.89038792481032 25.49641037519975 27.460500783669037 25.05042509715404 27.58608159594644 25.43940571879835 26.60862589878764 25.65573883459651 26.980157308264605 25.82360867389652 26.24932298173328 25.23457489936989 27.229503722269936 25.223142552341447 27.48446843844379 25.80147979181785 37.0 24.0 32.0 23.0 72.0 58.0 77.0 36.0 70.0 49.0 69.0 30.0 72.0 52.0 50.0 46.0 99.0 79.0 53.0 40.0 65.0 46.0 74.0 39.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.6942402997278094 0.00268017172806849 0.006910856026093958 GO:0071702 organic substance transport biological_process 28.07351350797577 28.410645954093685 28.095907953060518 28.38434317156857 28.207770744033894 27.859043002419693 27.712582862584572 28.263822608142647 27.713447203726567 28.08918604660212 28.1765435629536 28.45494910463355 28.23068586496433 28.6452032147306 28.38429699097047 28.7764097004316 27.616873730086322 28.09642660784717 28.30981237135588 28.77688982480412 27.768690267035517 28.144171374852125 27.987794487540807 28.497353956112427 28.385046730807108 28.61158025462845 267.0 262.0 255.0 236.0 261.0 281.0 277.0 325.0 322.0 346.0 354.0 268.0 331.0 309.0 258.0 325.0 371.0 381.0 287.0 272.0 316.0 325.0 358.0 431.0 5.0 6.0 4.0 6.0 6.0 4.0 7.0 5.0 9.0 8.0 8.0 4.0 9.0 8.0 10.0 4.0 9.0 5.0 8.0 4.0 9.0 8.0 6.0 5.0 -0.3371324461179164 0.017926339076638688 0.03379466943753034 GO:0071704 organic substance metabolic process biological_process 37.2894767927775 37.840510840787104 37.27312860047428 37.200676548192064 36.94301675836683 37.75582690697737 36.91918749549214 37.98569214913217 36.990585546615854 37.74556095938714 37.46318837124461 37.813117541387626 37.42889980282629 37.44343466061892 37.6582351136284 38.181863782923216 36.83454213758328 38.20978908893727 37.867087277966135 38.053775313463696 37.21788656919933 37.69464406536899 37.244507823483204 37.960361985244774 37.252613440080864 37.726542041082155 78478.0 77225.0 75941.0 96089.0 87812.0 122998.0 100469.0 115284.0 104656.0 117762.0 112434.0 89899.0 112786.0 117587.0 86707.0 119860.0 138491.0 131104.0 100424.0 97472.0 106313.0 109534.0 106119.0 117745.0 17.0 17.0 16.0 17.0 17.0 18.0 20.0 19.0 18.0 17.0 16.0 19.0 17.0 17.0 18.0 18.0 19.0 19.0 17.0 17.0 17.0 17.0 18.0 20.0 -0.5510340480096048 0.0012242832644312096 0.0037265988146589013 GO:0071705 nitrogen compound transport biological_process 27.428851849983676 27.76624143019268 27.302951038684736 28.041326647723533 27.402967171737966 26.746451392383623 27.03252309998614 27.413186271881557 27.32221197482428 27.445400581197518 27.773991992704172 27.85249950519917 27.863133889539924 28.13032144962291 27.23547762115741 27.7065319323318 27.06507072343072 27.043501891558805 27.1248302684334 28.31907679208766 27.07823586883504 27.512031133579523 27.55849389230549 27.962649582477606 27.966251230485 28.196942242756162 200.0 211.0 186.0 199.0 204.0 212.0 214.0 262.0 262.0 286.0 282.0 239.0 242.0 244.0 195.0 249.0 263.0 300.0 221.0 226.0 248.0 279.0 286.0 370.0 2.0 5.0 2.0 4.0 4.0 2.0 4.0 3.0 5.0 4.0 4.0 2.0 4.0 3.0 5.0 2.0 4.0 3.0 3.0 2.0 4.0 5.0 3.0 3.0 -0.33738958020900256 0.0734883472918226 0.11239394291690516 GO:0071806 protein transmembrane transport biological_process 25.681447391346826 26.459350621986264 26.10873621611964 26.818802559084176 26.21569504070042 25.37957150430545 24.98886994495409 26.084220125312964 25.61063655239648 26.10061151098622 25.578689345836864 26.45905857239881 25.87424917335179 26.787363666523962 25.602150727128787 26.40469020727408 25.00047281577908 25.72570854632066 25.637330171746893 27.02001292215664 25.258228079573026 26.329890770958986 25.74775850915287 26.64017706963682 25.979033358759786 26.893527949781753 81.0 77.0 76.0 73.0 71.0 66.0 69.0 98.0 86.0 93.0 96.0 80.0 86.0 83.0 62.0 91.0 98.0 104.0 70.0 84.0 80.0 95.0 94.0 133.0 4.0 3.0 3.0 2.0 4.0 3.0 3.0 4.0 4.0 4.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 4.0 3.0 4.0 5.0 -0.7779032306394384 0.0018227351663913985 0.005134928866041682 GO:0071840 cellular component organization or biogenesis biological_process 29.68693507627275 30.155094043668303 29.67741988905271 29.62975631375025 29.246364233643387 29.54369877782064 29.29771723208875 30.211891858273848 29.30671703092504 30.19020247806353 29.45296890577377 30.36928154476859 29.763049327998253 30.198000972990346 30.321626080037287 30.51077443012285 29.11914013026089 30.073480414773034 29.6868776831327 30.322310721165504 30.278552937734126 29.98222360826345 30.083223720082163 30.460068761091605 29.334260179161234 30.043651420037524 410.0 326.0 353.0 481.0 311.0 507.0 332.0 435.0 460.0 513.0 473.0 489.0 487.0 596.0 354.0 534.0 561.0 562.0 431.0 422.0 454.0 542.0 419.0 524.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.46815896739555285 0.009374768459434895 0.01937038251220985 GO:0071941 nitrogen cycle metabolic process biological_process 25.822609330916105 26.42352225773563 24.694905260419684 25.140108805408612 25.948283467399072 26.626135296423758 25.573357231321932 26.05814170909659 24.78779297975073 25.885095042735426 25.884379508537997 25.96796483182691 26.665309637506212 26.059218945529352 25.751467791281662 27.15277896703125 24.31930596649855 26.8465977416322 24.727814063183125 25.11230163272284 26.959472005829273 26.56232707457002 25.083160434384226 27.445289635542608 26.599939702331945 26.325934980039076 28.0 22.0 26.0 33.0 39.0 24.0 35.0 35.0 30.0 41.0 40.0 14.0 41.0 39.0 26.0 40.0 39.0 20.0 50.0 39.0 37.0 45.0 45.0 48.0 2.0 1.0 3.0 3.0 3.0 1.0 3.0 3.0 3.0 3.0 3.0 1.0 3.0 2.0 4.0 2.0 2.0 2.0 4.0 2.0 4.0 3.0 4.0 3.0 -0.6009129268195252 0.03766692222862868 0.06276144050911694 GO:0072330 monocarboxylic acid biosynthetic process biological_process 28.88011820542509 29.73755118258709 29.24238651475281 29.01004675936073 28.82855030400669 29.75780956419725 28.32268275516705 29.93307122778911 28.07574786034161 29.65409125854313 28.85488029861725 29.62865446883112 28.82987822421125 29.135151262358626 29.448223635991987 30.098928475507 28.43548612530992 30.30852162776275 29.66695738637302 29.94617067835269 28.82036092677033 29.6200941965712 28.498527206254806 29.73741129467793 28.694806130211905 29.51921857668661 145.0 135.0 178.0 204.0 177.0 231.0 202.0 209.0 200.0 199.0 177.0 136.0 227.0 203.0 170.0 221.0 301.0 224.0 188.0 192.0 191.0 185.0 184.0 205.0 3.0 3.0 4.0 3.0 5.0 3.0 4.0 4.0 4.0 4.0 5.0 4.0 5.0 3.0 5.0 3.0 6.0 4.0 4.0 4.0 4.0 5.0 5.0 4.0 -0.8574329771619986 0.00034415785384659113 0.0013990521224773477 GO:0072521 purine-containing compound metabolic process biological_process 32.283272697422404 32.93961247808203 32.320582921871036 32.3414015302928 31.983845360211514 32.88562854154136 31.99933900451286 33.106965239434274 32.04171601313002 32.869797845217484 32.51774691584973 32.794036461079195 32.45927234596925 32.47840341453649 32.693533984592946 33.312290251265665 31.840923264668888 33.37442762962474 32.72312027063021 33.137684304387136 32.11915340017872 32.82299091092853 32.06839105250163 32.97400623234333 32.3010638570126 32.83472244545809 2352.0 2212.0 2414.0 2783.0 2685.0 3649.0 3030.0 3248.0 3023.0 3226.0 3200.0 2403.0 3225.0 3485.0 2502.0 3394.0 3954.0 3788.0 2982.0 2995.0 2981.0 2894.0 3023.0 3342.0 6.0 5.0 5.0 5.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 -0.6563397806596285 0.0001748865925420931 0.0008236168584623857 GO:0072522 purine-containing compound biosynthetic process biological_process 30.0663435352566 30.71919712105885 30.077038695881534 30.204407378658967 29.681296342535852 30.65906042399412 29.925304660995174 30.869357213233084 29.87475640600716 30.653761513946204 30.364606636674147 30.58130386465693 30.352053909221745 30.33435384160801 30.366273263893127 31.08367111219988 29.623399937677828 31.08315999000327 30.44408787797204 30.89568620145873 29.873706340636968 30.590513081248808 29.846110276993986 30.81889297553371 30.06080330785886 30.58339475059932 569.0 577.0 559.0 667.0 645.0 875.0 708.0 798.0 720.0 791.0 771.0 601.0 756.0 859.0 598.0 833.0 929.0 937.0 691.0 732.0 683.0 712.0 714.0 829.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 -0.6528535858022515 0.00021985068263840352 0.0009941074345388681 GO:0072523 purine-containing compound catabolic process biological_process 20.919746836507443 21.85730416841809 20.651716982861885 NA NA NA 19.583897507614886 22.033940519237067 20.157375089228026 22.887493169293556 20.5012280089838 22.53867954142091 21.80209532335836 20.940440126713533 20.145468983846808 21.017960072508718 19.53843142466959 21.741015139271145 21.204139981203905 21.44490436895219 20.72087340811253 20.257466593257508 22.42012395422932 20.97650610857601 20.41636491713456 22.52481197668689 8.0 NA NA NA 5.0 10.0 8.0 18.0 7.0 13.0 8.0 7.0 3.0 8.0 3.0 9.0 8.0 11.0 6.0 3.0 12.0 6.0 6.0 13.0 2.0 NA NA NA 3.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 1.0 1.0 2.0 2.0 2.0 1.0 2.0 1.0 1.0 2.0 -0.9375573319106465 0.016656305210212025 0.032128390884612994 GO:0072524 pyridine-containing compound metabolic process biological_process 30.09790736361138 31.245566789191688 30.70482701604727 30.634922123854817 30.39848361805771 31.33333985043841 29.4912253560314 31.476101173291912 29.005465462480522 31.06659012150161 29.990036938196074 31.02729622142871 29.813198193858533 30.642561841803822 30.881193008266877 31.64123818066498 29.527663812336648 31.792795069304557 30.852876831325112 31.46558062887907 29.87487796618136 31.14668799671313 29.326751558668324 31.251331649500628 29.856579634887357 30.97406167141957 420.0 459.0 522.0 571.0 456.0 698.0 486.0 610.0 514.0 596.0 524.0 488.0 650.0 641.0 437.0 604.0 788.0 661.0 548.0 569.0 518.0 619.0 508.0 561.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 -1.1476594255803079 0.0001386794054294884 0.0007006959432226783 GO:0072525 pyridine-containing compound biosynthetic process biological_process 28.475981585485748 29.633313728357766 29.09922590358209 29.005156271598945 28.775723360214602 29.72431274524897 27.869822993773926 29.86026994125196 27.37292127440377 29.450887838232504 28.381777777282625 29.41228401987061 28.18703235460465 29.006804460682435 29.27550797559359 30.044196675280947 27.90908096128514 30.199868407227783 29.2033211434332 29.850714695829712 28.23859569603597 29.532598782368087 27.69179687425655 29.644257946754397 28.24294599961733 29.34226551386423 134.0 143.0 169.0 187.0 143.0 220.0 154.0 191.0 164.0 186.0 164.0 150.0 205.0 206.0 139.0 194.0 243.0 207.0 173.0 182.0 163.0 195.0 160.0 180.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 -1.1573321428720185 0.0001386794054294884 0.0007006959432226783 GO:0072527 pyrimidine-containing compound metabolic process biological_process 29.69091522516839 29.958425751883034 29.39283159180959 29.065913896182103 28.7314788700875 29.408990758093122 29.167296988179242 29.879985466483358 29.24261801060523 30.196871274941092 30.12689372230485 30.499300990991184 30.146500388767233 29.97556276813549 29.110287844920997 29.81158505369536 29.361115573044845 29.711268506127052 30.18050449771641 29.87623697316053 30.35763334607811 29.69950788411797 29.752818971877165 30.638248355810433 29.719549195317374 30.03753953408778 642.0 654.0 409.0 712.0 734.0 978.0 838.0 1055.0 831.0 1145.0 1047.0 863.0 877.0 901.0 822.0 1089.0 1178.0 1114.0 843.0 691.0 1049.0 1175.0 1049.0 1065.0 6.0 6.0 5.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 5.0 6.0 4.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 -0.2675105267146449 0.2040238704744366 0.2705863871967023 GO:0072528 pyrimidine-containing compound biosynthetic process biological_process 28.34657572548748 28.58532836031793 28.101560619527877 27.63116867111527 27.119505395156242 27.99408411857164 27.85242676745505 28.489626028513737 27.942803612904555 28.871452115055646 28.836161320935613 29.19620598724213 28.79365807474859 28.577005945505014 27.710976826564803 28.36847245941212 28.023956159018983 28.311353889988666 28.817139126993297 28.504940314487552 29.07030539864973 28.375814504333224 28.4064920615383 29.240217952138085 28.307140021078226 28.684113967481537 233.0 221.0 135.0 241.0 269.0 319.0 315.0 358.0 300.0 401.0 357.0 277.0 316.0 298.0 303.0 368.0 417.0 389.0 296.0 237.0 369.0 398.0 372.0 362.0 5.0 5.0 4.0 5.0 4.0 5.0 4.0 5.0 5.0 5.0 4.0 5.0 3.0 5.0 4.0 5.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 -0.23875263483045117 0.2253456937016668 0.2954111614912607 GO:0072594 establishment of protein localization to organelle biological_process 23.688562709631714 24.7639651083044 23.65409895197369 25.35816592571525 20.758143888416818 NA 24.158978711523037 24.72678833399889 23.512955080840875 24.437427383212448 24.13281249253365 24.858854164767198 24.13466419226313 25.078201663135143 24.277993435363626 24.029790499716267 22.495605236465245 23.03361691358689 22.913817422179807 25.6735572041773 19.08058658367429 24.028283855426068 23.46033802903595 23.743271421291862 24.99734477369905 25.379899148184442 2.0 2.0 4.0 NA 4.0 5.0 6.0 7.0 7.0 12.0 7.0 4.0 6.0 6.0 5.0 4.0 5.0 6.0 1.0 5.0 2.0 3.0 4.0 5.0 2.0 2.0 3.0 NA 4.0 3.0 2.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 1.0 3.0 2.0 3.0 4.0 3.0 -1.0754023986726864 0.013823023820376656 0.02725297587334924 GO:0080090 regulation of primary metabolic process biological_process 28.27448853762576 28.915429125816487 28.354454040112948 28.52243992745755 28.443034587305625 28.825475613666004 27.87127338737805 29.16614653276741 28.204711068068384 29.10397666878613 28.239551079416103 29.07020463391461 28.253890320254946 28.743288928370344 28.38582813254573 28.803807988550805 27.670350277790842 28.86877189166087 28.717213265384487 29.333256038881522 28.420820094533802 28.61748365857263 28.145920825798157 28.75525022354941 28.316394822175088 28.95911898109196 226.0 256.0 218.0 249.0 238.0 353.0 294.0 361.0 320.0 335.0 327.0 287.0 271.0 313.0 210.0 333.0 408.0 388.0 269.0 243.0 267.0 332.0 333.0 370.0 3.0 3.0 4.0 3.0 4.0 4.0 3.0 3.0 4.0 3.0 5.0 4.0 2.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 4.0 3.0 -0.6409405881907269 5.312128159411724e-05 0.0005099643033035255 GO:0090150 establishment of protein localization to membrane biological_process 22.683229735584487 21.041953803866296 20.27905969622881 NA 16.127933205440993 NA 21.64427351042969 20.320266833426217 20.8568684738792 21.38779268409069 22.737697338490506 22.237212813930586 22.839331521104345 20.009216565802493 20.54860216372923 20.84774867193229 22.868625726206 20.42231294133125 24.09970400643196 22.010652479368677 23.1819527043366 20.233866476326746 23.42651948111876 19.625971469598838 23.49709654186913 20.915729533401613 3.0 NA 2.0 NA 5.0 3.0 3.0 4.0 7.0 9.0 6.0 2.0 4.0 4.0 7.0 2.0 28.0 4.0 5.0 3.0 6.0 1.0 7.0 5.0 1.0 NA 1.0 NA 2.0 1.0 1.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 1.0 2.0 1.0 2.0 1.0 1.0 1.0 2.0 2.0 1.6412759317181909 0.034856847263039586 0.059509364410770725 GO:0090304 nucleic acid metabolic process biological_process 29.902988301931423 30.59194871394941 29.558599740751518 30.13607955342999 29.365275220334983 30.54703875960865 29.613588784723106 30.627834789990807 30.105923313031624 30.30168860155181 30.294376552697873 30.62139764613832 30.2212698405417 30.679539741968583 29.966552729846626 30.87341785670138 29.317030598317213 30.516283702804238 30.2127099780128 30.824475878203202 29.79976430146016 30.26220916432336 30.01030309260189 31.050002904501905 29.95516061232904 30.38576244640139 1110.0 1496.0 1024.0 1727.0 1352.0 1922.0 1513.0 1745.0 1847.0 1962.0 1788.0 1772.0 1570.0 2135.0 1129.0 2079.0 2123.0 2060.0 1229.0 1521.0 1543.0 2201.0 1694.0 1817.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 -0.6889604120179875 8.637667594722788e-05 0.0006159890947550879 GO:0090407 organophosphate biosynthetic process biological_process 32.31106429424467 33.049587159654884 32.39200068258314 32.38376863073742 32.000664504932836 32.93273385935765 31.992231181741147 33.21136605546365 31.92150152054727 33.00262287301615 32.51209413859148 32.98422626036031 32.49417627946624 32.612534696197116 32.626832387975995 33.416316418406055 31.89304800043745 33.46921445154254 32.825520343892784 33.194154073463615 32.38667386971619 32.915309257784 32.055824728688656 33.169144899556564 32.27115001832076 32.955019109315074 2730.0 2699.0 2567.0 3215.0 3046.0 4293.0 3411.0 4041.0 3502.0 4081.0 3867.0 3103.0 3721.0 4080.0 3080.0 4200.0 4599.0 4504.0 3481.0 3449.0 3629.0 3796.0 3743.0 4176.0 6.0 8.0 6.0 7.0 9.0 7.0 8.0 8.0 10.0 10.0 9.0 9.0 9.0 8.0 9.0 8.0 10.0 8.0 10.0 6.0 10.0 8.0 10.0 9.0 -0.7385228654102107 0.00021985068263840352 0.0009941074345388681 GO:0090529 cell septum assembly biological_process 25.891381108613853 26.912750590855822 26.412433497711795 26.70000639281273 26.27095257011268 25.993438654845036 24.70272219188899 27.02568133983125 25.473114074003767 26.942103503177552 25.08812866326053 27.08411378467302 25.449445722300485 26.926425943063588 26.40319212387965 27.18470746068029 25.466724727127552 26.66890007102272 26.365819187340588 27.365615770714413 26.2012252562849 26.586827786974663 26.11348023321025 27.14124786037393 25.572285115619856 26.88453228723091 61.0 57.0 49.0 44.0 34.0 74.0 34.0 76.0 43.0 60.0 47.0 59.0 69.0 78.0 33.0 70.0 61.0 88.0 48.0 69.0 40.0 71.0 49.0 70.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.021369482241969 0.0001386794054294884 0.0007006959432226783 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process biological_process 24.808800787447343 25.739959675642844 24.49298799291791 25.01173260760924 24.05984457503732 25.92454301763381 24.71513901881273 25.662391772572263 25.518750911042943 25.23182913380094 25.50314989711503 25.88324515523204 24.739654071073065 25.599606737953486 24.71392437598839 26.278732020538694 23.83779254000146 25.9144137559386 25.25626223893572 25.982532492917976 23.958379462609482 25.580499154234303 24.922713719923586 26.072946211019783 24.823728318600804 25.17934426610448 16.0 24.0 18.0 25.0 25.0 31.0 39.0 33.0 34.0 35.0 24.0 20.0 31.0 34.0 19.0 40.0 34.0 39.0 25.0 28.0 35.0 39.0 26.0 33.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.9311588881955011 0.0002755038114342687 0.0011655212090507369 GO:0097159 organic cyclic compound binding molecular_function 34.10596213879153 34.05784611570875 33.63382607284274 33.412256258790194 33.56811962832225 34.12305487140038 33.821445716610064 34.13759434856473 34.16741268068593 34.015642012839024 34.28139284522564 34.15251271755881 34.165449693708844 33.77215829521815 34.25874171111508 34.17648683345762 33.71505161921421 34.01203799632702 34.67475305954914 34.27017908849463 34.30332001360302 34.13195115056892 34.21696182804841 34.10543572875594 34.06226394931073 34.194164134456585 5408.0 5029.0 4737.0 6792.0 7180.0 7961.0 8778.0 7548.0 8825.0 7878.0 8425.0 6316.0 9340.0 7788.0 6769.0 7749.0 11035.0 9694.0 6561.0 6288.0 8337.0 7533.0 8247.0 7977.0 10.0 7.0 10.0 8.0 10.0 10.0 9.0 11.0 9.0 11.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 11.0 0.048116023082783954 0.4529203011037244 0.5347630423627702 GO:0097164 ammonium ion metabolic process biological_process 24.461462524694824 24.53603108186177 19.286819835017393 22.957795796899276 18.383088373129283 15.079582061422512 24.46937011886752 22.141222778611308 23.92309411263039 24.60408133326437 24.849843565642534 22.26506968986465 22.633978719542664 21.255883151582523 19.908321163321308 19.427299559932074 23.00811184309445 20.587353569948302 27.107895090431647 27.82063437215077 25.010582651694595 18.509220775954145 22.750540308860245 18.486598670821106 22.373374130408386 22.514670117825112 2.0 2.0 3.0 2.0 9.0 6.0 16.0 25.0 11.0 6.0 7.0 4.0 6.0 3.0 6.0 5.0 58.0 37.0 19.0 2.0 8.0 3.0 10.0 5.0 2.0 2.0 3.0 2.0 3.0 3.0 4.0 5.0 4.0 3.0 3.0 3.0 2.0 2.0 3.0 2.0 6.0 5.0 4.0 2.0 3.0 2.0 5.0 4.0 -0.07456855716694477 0.14891467317876572 0.20512749682902828 GO:0097171 ADP-L-glycero-beta-D-manno-heptose biosynthetic process biological_process 23.44041337674305 22.08096806201888 20.930030021238387 NA NA NA 23.26626509783469 22.498416316248022 22.863946480253905 23.203676203546816 23.91525673134897 22.699524314957447 24.23876167013248 21.034128960075968 21.963646662746648 20.60800527989789 23.423817872263665 22.252363185597392 23.707435893109693 21.48645652613475 23.584405248278962 20.235839366304727 23.45953873754065 19.026237331402136 23.99548268065958 23.0222120180868 8.0 NA NA NA 15.0 11.0 14.0 14.0 18.0 16.0 24.0 4.0 10.0 5.0 18.0 9.0 25.0 8.0 21.0 3.0 24.0 3.0 22.0 17.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1.3594453147241694 0.003887698060104835 0.009377869824763952 GO:0097305 response to alcohol biological_process 18.696578774088376 21.95376802813304 17.041541616741096 21.215515926602414 14.802535732482758 21.4531044018516 16.19463320873981 21.85520971241421 19.39669951353797 21.843828761187762 20.7637050754652 22.70712252864921 14.889243061109436 20.724190290592045 NA 21.445661817994075 18.0178046006368 23.32709062988541 18.161380949769033 22.189294848181486 NA 19.599950495276754 19.61272291913899 22.935393263326787 17.183086880705268 18.301723201613555 2.0 6.0 2.0 2.0 2.0 6.0 4.0 2.0 4.0 8.0 2.0 8.0 NA 4.0 4.0 8.0 4.0 6.0 NA 2.0 4.0 12.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 -3.2571892540446648 0.00036993149163163074 0.0014703009603703032 GO:0097367 carbohydrate derivative binding molecular_function 32.10636695733914 31.594643146626037 31.262773866093678 30.73968139717585 31.120154626633052 31.76441418313444 31.831415224384926 31.59110694040518 32.289310977724234 31.572168042850905 32.364312782852245 31.77120554044356 32.20163539151535 31.297480417568675 32.149996724846304 31.54973465852188 31.63137265166829 31.430457201525808 32.71084811564107 31.809912072199968 32.4765681768301 31.818212291127313 32.30725522217242 31.658923295383953 32.10591304474801 31.809043586321238 1207.0 1081.0 1000.0 1436.0 1662.0 1782.0 2059.0 1707.0 2012.0 1740.0 1893.0 1327.0 2136.0 1665.0 1560.0 1720.0 2522.0 2219.0 1461.0 1376.0 1936.0 1623.0 1911.0 1760.0 2.0 3.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 4.0 2.0 3.0 2.0 2.0 3.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 0.5117238107131037 0.011074437676156606 0.022291771322328135 GO:0098660 inorganic ion transmembrane transport biological_process 27.351634866698426 28.25256666036693 27.042668936114488 27.502852274197416 26.70862013837897 28.11260123934391 26.979660812993234 28.28936706127305 27.153420208672138 28.205890659304856 27.44323786849068 28.337128402785602 27.46713851818236 27.75419153441037 27.14161569172705 28.7069160392339 27.04661781360156 28.61080343337288 28.04264724849862 28.258349228245482 27.876378494705683 28.139161456337792 27.426841089066638 28.37199049698459 27.32040086106399 28.348456195594984 106.0 98.0 102.0 133.0 107.0 136.0 131.0 138.0 125.0 138.0 127.0 101.0 136.0 135.0 92.0 134.0 144.0 158.0 131.0 129.0 127.0 105.0 125.0 152.0 1.0 2.0 2.0 3.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 1.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 -0.9009317936685051 8.637667594722788e-05 0.0006159890947550879 GO:0098796 membrane protein complex cellular_component 28.266567489570175 28.880299991393148 28.504737160252013 28.59055358486928 28.825097355927127 28.62983661942393 27.74653419280057 28.8925144014415 27.64646571723962 28.72365828644619 28.150345922233033 28.890512579335823 28.22756978219486 28.73076466977284 28.451724380803785 29.376752179129802 27.88039851479497 28.932186437962393 28.533963570144657 28.887818223356767 28.717847685808874 28.787829773164226 27.81939726767703 29.110345229394717 28.110324109913524 28.826953313549943 210.0 188.0 202.0 221.0 162.0 290.0 225.0 257.0 229.0 270.0 219.0 207.0 224.0 245.0 179.0 230.0 261.0 289.0 226.0 248.0 221.0 247.0 263.0 289.0 6.0 4.0 4.0 5.0 5.0 5.0 6.0 6.0 8.0 7.0 6.0 7.0 6.0 5.0 6.0 7.0 9.0 7.0 4.0 5.0 6.0 5.0 7.0 8.0 -0.6137325018229731 0.0001748865925420931 0.0008236168584623857 GO:0101030 tRNA-guanine transglycosylation biological_process 20.085481470017733 21.28056125496289 21.411686574804285 21.364942325333548 20.664206675872585 21.988566469466967 18.93568550275284 21.45970467533689 18.45031637270289 20.099243862095694 20.452177304234226 21.02280740949204 19.36976476606189 20.539550847874327 17.89278798280013 22.057261722206306 18.327128086860988 21.115800064246727 19.38801348454509 21.546780353899585 20.857835637147847 21.59359354660044 21.09636195983462 20.382545635355868 19.008289140532533 20.789450881600565 2.0 7.0 5.0 8.0 3.0 6.0 3.0 3.0 5.0 8.0 4.0 2.0 2.0 7.0 2.0 8.0 3.0 6.0 5.0 8.0 3.0 4.0 3.0 4.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1950797849451575 0.0032349119169146935 0.007931571851295751 GO:0102009 proline dipeptidase activity molecular_function 22.64063380294339 23.824846730823985 24.347919008467144 24.444908718248225 23.344279543594517 23.49182011686253 19.292896645245968 23.41835308928753 19.75001604989313 24.35806411116341 21.749625910166635 24.24971031737079 21.97386103842673 23.488665354179982 21.916672065113048 22.95043161443902 22.053752734483368 20.415325689658307 23.867488918333787 25.096625736874927 21.248781251854922 23.02842410801397 21.552036764218908 23.329658242242907 22.951711243443995 23.815556932869054 14.0 8.0 20.0 16.0 4.0 5.0 5.0 11.0 6.0 10.0 8.0 6.0 7.0 4.0 3.0 3.0 19.0 14.0 10.0 4.0 10.0 10.0 17.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.1842129278805942 0.013042519940568903 0.025877686622941164 GO:0102132 3-oxo-pimeloyl-[acp] methyl ester reductase activity molecular_function 21.809451155590075 23.111744724227172 23.23538924938273 22.766486339000412 22.50353845204844 21.6516861480088 20.840173799517924 23.582263618088607 20.272792175698246 23.64614918086949 20.466222357642735 23.31402077527313 20.358798830462774 22.85648474723228 22.551087147081237 23.102476356283173 21.74398758829155 23.326585434166976 21.72700939150887 23.43557104397571 22.488932296117266 22.966925340349512 20.385065606276648 22.74045982504038 20.90301455840729 23.028069329587158 11.0 13.0 14.0 13.0 6.0 18.0 4.0 18.0 4.0 15.0 3.0 12.0 14.0 14.0 6.0 13.0 9.0 13.0 13.0 16.0 8.0 10.0 7.0 14.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.302293568637097 0.0005320055051392492 0.0019244720881558927 GO:0102500 beta-maltose 4-alpha-glucanotransferase activity molecular_function 20.241434839691745 21.44110457458449 18.934774494517992 21.97679997608604 21.1771457419344 21.10013612386448 18.86654321706262 21.041765642636303 15.925153414510019 20.03836129053717 16.843824732971868 20.81707377575037 21.638743291944397 19.721565267927986 21.540885921419157 21.37339731446563 NA 19.8529237592704 17.315190789242568 20.829746824102283 20.601391770649293 20.96855684853573 17.594708992147048 23.460449979027658 20.80914473826987 21.376064947189725 3.0 10.0 3.0 10.0 1.0 8.0 1.0 5.0 2.0 6.0 9.0 3.0 8.0 7.0 NA 6.0 2.0 3.0 6.0 6.0 3.0 12.0 8.0 12.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.199669734892744 0.04889984922191003 0.07872902492059129 GO:0102752 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) molecular_function 21.70631237234818 21.221695848770985 22.709819258423142 21.011478750385145 22.965685949627947 20.304624592011443 19.869646665298397 22.25522558230036 17.985943262303927 20.687459207269512 21.533738364651647 22.375297433884267 22.51359909984412 21.869291453471426 21.907520779960947 20.62815371787996 18.994770296818388 20.377044703551775 21.319003513025386 21.443862692183426 22.428114987779445 21.307050515181594 19.23037124804879 19.728732171955503 21.21693089199749 19.358908101476466 6.0 4.0 9.0 4.0 4.0 9.0 2.0 4.0 6.0 6.0 10.0 3.0 8.0 5.0 2.0 4.0 8.0 5.0 12.0 8.0 2.0 4.0 5.0 1.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.48461652357719487 0.4884223166225936 0.5675521891480417 GO:0103046 alanylglutamate dipeptidase activity molecular_function 21.412855899833023 20.654962221601576 NA NA 20.45724133476636 19.748001310246643 19.82201137798674 21.006652809623503 16.943056020831648 21.315077017582677 20.10036740587433 21.33926436030711 21.707792073445592 19.81743652568018 21.963243249333207 19.265635260563613 18.512875887387008 20.531667000172146 24.05944375987241 21.07579580965388 19.087104817922768 18.016424966423568 15.969556592952063 20.36836910270328 20.07301524432625 21.52281404109284 NA NA 8.0 5.0 2.0 5.0 1.0 7.0 3.0 6.0 10.0 2.0 2.0 4.0 1.0 3.0 12.0 5.0 3.0 2.0 1.0 3.0 2.0 5.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.7578936782314472 0.5767401907472749 0.6478593681841576 GO:0103111 D-glucosamine PTS permease activity molecular_function 26.31024571252276 26.03181325035755 27.139613810380922 25.83884193785649 27.202203674165037 25.6445948410808 25.42000156502837 26.666414149097648 25.72294824194347 26.685269362939753 26.15608203938073 26.71356674176736 25.17420621686834 25.081014149294013 26.39263236266025 24.948552254662967 24.49442903417809 26.363574394546017 26.880693504393268 25.862919545798515 26.96566721136373 25.680474905507488 25.400006457954806 25.23375611379837 26.11538937641091 26.21413370406885 61.0 15.0 64.0 25.0 28.0 29.0 29.0 29.0 42.0 37.0 33.0 16.0 47.0 34.0 23.0 15.0 56.0 31.0 60.0 27.0 37.0 28.0 52.0 40.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.27843246216520967 0.4884223166225936 0.5675521891480417 GO:0103117 UDP-3-O-acyl-N-acetylglucosamine deacetylase activity molecular_function 20.119348232852925 20.469590754302 18.50502363022481 NA NA NA 18.762251682677764 19.9425993452968 19.506766147426816 21.10385584779268 20.281748887514073 21.825119758666087 21.765602188445268 21.516431546571997 19.5074349434548 15.7405969911101 19.06893774968019 17.06118218255579 20.491961289103546 20.58268225898723 18.75936874146036 19.404484153468008 20.555444758642565 19.979548914923075 20.388695755194952 20.006773233714885 2.0 NA NA NA 1.0 3.0 2.0 4.0 3.0 5.0 6.0 3.0 1.0 1.0 1.0 2.0 7.0 3.0 1.0 3.0 3.0 4.0 3.0 3.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.35024252144907564 0.5732013209481351 0.6444641878768222 GO:0106130 purine phosphoribosyltransferase activity molecular_function 23.057983310355212 25.270498252683172 24.39435955850829 25.48037512782007 22.999685076426182 25.105723327813955 22.181366573230605 25.53634187406341 22.273064789275832 24.92645662785539 22.50080858706952 24.663647868949266 23.716833937485113 25.75883037438515 23.516753322035626 25.205194317420172 22.033558798362503 24.53024738318914 23.5811778857924 25.347712048233966 22.74118507841084 24.91236686738884 22.087471437279802 26.21581040405486 22.099710149912266 24.50090841835595 16.0 32.0 9.0 17.0 12.0 32.0 12.0 32.0 14.0 29.0 13.0 27.0 19.0 30.0 13.0 30.0 30.0 34.0 12.0 24.0 11.0 30.0 9.0 31.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 4.0 4.0 3.0 3.0 4.0 3.0 3.0 4.0 -2.21251494232796 3.225641456243767e-05 0.0005099643033035255 GO:0140096 catalytic activity, acting on a protein molecular_function 28.803840419752024 29.911574281145025 29.538483479412953 29.38736404444868 28.879157589427802 29.469228844188446 28.003546631495183 29.94574782017627 28.84849774563438 29.84118547839322 28.81478862908022 30.25380234052985 28.82742193138062 29.65736049203473 28.921364789757728 30.1242730573217 28.2423264278826 30.312833911352467 29.30352518138209 30.22063884406879 28.27939176702145 29.465460872161714 28.499806321358555 30.09450426456363 28.761499293780226 29.75731198229756 472.0 561.0 475.0 709.0 352.0 768.0 458.0 724.0 487.0 713.0 528.0 627.0 535.0 888.0 367.0 909.0 714.0 802.0 404.0 665.0 425.0 815.0 481.0 779.0 10.0 12.0 8.0 10.0 11.0 12.0 11.0 11.0 10.0 12.0 11.0 10.0 10.0 10.0 8.0 9.0 10.0 11.0 9.0 8.0 12.0 10.0 10.0 9.0 -1.107733861393001 6.784570247173055e-05 0.0005498145239267514 GO:0140097 catalytic activity, acting on DNA molecular_function 24.63850692323248 24.42885333124222 23.54937031907492 24.600747190492267 23.87343509236625 24.992750658549408 24.321438688728012 24.39663182297441 24.31543698932325 24.04788302930046 24.734148846391932 24.451224895431622 24.90462858034185 24.73693651173521 23.24342566006949 24.27504055751059 24.05362984591459 23.321473903931803 24.008833350811038 24.33636591036078 26.62182140248116 23.59562459294505 23.50887955761189 24.980563826935644 24.585709577101067 24.523327488598447 26.0 57.0 24.0 40.0 63.0 44.0 54.0 41.0 88.0 53.0 92.0 66.0 42.0 61.0 42.0 33.0 55.0 53.0 30.0 26.0 49.0 66.0 86.0 72.0 6.0 9.0 8.0 8.0 7.0 10.0 7.0 8.0 9.0 8.0 9.0 9.0 8.0 9.0 8.0 7.0 8.0 9.0 5.0 7.0 7.0 9.0 7.0 9.0 0.20965359199026068 0.3556110610952391 0.43337630976650365 GO:0140098 catalytic activity, acting on RNA molecular_function 28.8482574162499 29.230460017235032 28.11142962269433 28.522082878623642 27.829482574085823 29.279453715807296 28.58603851694141 28.95471999883111 29.541047198551286 28.90241245537984 29.289726272076074 29.100261343644977 29.09207068051613 29.132473585714827 28.98812002865509 29.52964773404625 28.38596413658797 29.112651237915912 29.4145566048066 30.09123496716465 28.34358785040898 28.735037893016553 28.680124159357533 29.662696497596983 28.863932953365588 29.00620605623413 393.0 514.0 392.0 648.0 591.0 723.0 739.0 739.0 804.0 715.0 817.0 637.0 693.0 788.0 507.0 802.0 957.0 892.0 475.0 595.0 716.0 828.0 742.0 735.0 6.0 6.0 6.0 6.0 6.0 6.0 5.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 6.0 -0.38220260098513137 0.0734883472918226 0.11239394291690516 GO:0140101 catalytic activity, acting on a tRNA molecular_function 28.52588246174612 28.640598153437143 27.39568518909198 28.05311734183621 27.37117530262257 28.67838978498489 28.39802871927891 28.49922341961869 29.277029037930106 28.314610298262448 29.086499859479517 28.678179694834302 28.86476909825911 28.597281672487565 28.804017961900534 29.055794418837706 28.127404574014665 28.548330780691252 28.65963616553097 28.9108604725102 27.54577497671153 28.359046324063225 28.60093706296892 29.041094331110806 28.698644667546702 28.621007736859887 265.0 294.0 274.0 364.0 517.0 474.0 665.0 517.0 658.0 474.0 655.0 402.0 587.0 458.0 444.0 496.0 791.0 633.0 347.0 399.0 640.0 479.0 600.0 521.0 8.0 10.0 7.0 8.0 10.0 10.0 7.0 10.0 10.0 10.0 9.0 11.0 6.0 8.0 8.0 12.0 10.0 10.0 7.0 8.0 7.0 11.0 10.0 9.0 -0.11471569169102125 0.8173613313851769 0.8543274217493305 GO:0140110 transcription regulator activity molecular_function 24.416519288467175 24.85250393531683 24.45635482439588 24.297786179555906 24.235993239760838 24.42740040896189 23.536421885937468 24.794550789965893 22.795769130181107 25.23276106362895 23.592528524492607 25.07018793368029 25.195450648721124 24.79306878254705 23.755270865505004 25.009309149375838 23.833814805116486 24.91520134418631 25.96105323942632 25.428705177565817 24.761786373935085 23.90696954747181 24.24950276760668 24.98928101730401 23.58562231277317 24.733597441702795 32.0 43.0 37.0 41.0 23.0 50.0 21.0 41.0 22.0 44.0 33.0 52.0 28.0 45.0 22.0 48.0 62.0 65.0 41.0 36.0 27.0 44.0 36.0 35.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.4359846468496542 0.017926339076638688 0.03379466943753034 GO:1901068 guanosine-containing compound metabolic process biological_process 26.04123618679121 27.028587898250947 26.269159264982854 27.02609324354355 26.69036963000235 27.029541375811103 25.38084654971621 27.009018302826185 25.29409883407452 26.539814782445067 25.66595014331523 26.697936423262785 26.50407234820641 27.11619394640687 25.597994915511517 27.04185135910728 25.598181532227674 26.91572985861103 25.661744476538324 27.579960449977282 26.58834657332361 26.809834211187635 26.28377659125485 27.02820920540507 26.03970423555921 27.274219194303303 70.0 60.0 100.0 125.0 55.0 106.0 78.0 93.0 73.0 87.0 99.0 72.0 74.0 111.0 58.0 108.0 94.0 79.0 108.0 99.0 85.0 90.0 78.0 114.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 -0.9873517114597377 5.312128159411724e-05 0.0005099643033035255 GO:1901070 guanosine-containing compound biosynthetic process biological_process 25.01216310820407 26.00232643326357 25.21309285373529 26.00216106880107 25.672304294303828 25.997751086396928 24.347149889637965 25.996596981359662 24.276540940037407 25.51864399214229 24.600563617689282 25.674961429609326 25.471848956413695 26.07005220940433 24.589670838544173 26.001410850016466 24.560630134953648 25.874135555905852 24.638467532498932 26.56817198812035 25.582985606863407 25.79337387614089 25.27077781936433 25.987709714248446 24.98470541565605 26.26218011751489 32.0 27.0 47.0 57.0 24.0 50.0 37.0 44.0 31.0 42.0 44.0 32.0 36.0 46.0 26.0 48.0 44.0 37.0 52.0 47.0 41.0 41.0 33.0 55.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 1.0 2.0 1.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 -0.9901633250594983 5.312128159411724e-05 0.0005099643033035255 GO:1901135 carbohydrate derivative metabolic process biological_process 32.686415860844676 33.49658916447967 32.84465719132313 32.947452392595245 32.59540716225326 33.419326703263074 32.256226689196836 33.681887567518075 32.242389004367574 33.39344478835416 32.77622591038651 33.3854501049658 32.85109267802436 33.144399931364745 33.01228278291127 33.826888865147765 32.23031499056729 33.84105794406674 33.223736974654834 33.691655855357126 32.74512414365634 33.35980165250438 32.443062719891245 33.598709877704444 32.6318134998591 33.4023779511882 4066.0 4109.0 4034.0 5080.0 4253.0 6534.0 4798.0 6101.0 4941.0 6073.0 5626.0 4687.0 5268.0 6103.0 4242.0 6244.0 6821.0 6575.0 5203.0 5206.0 5173.0 5618.0 5216.0 6268.0 19.0 19.0 19.0 19.0 20.0 19.0 20.0 20.0 21.0 19.0 19.0 20.0 19.0 19.0 21.0 19.0 21.0 20.0 21.0 18.0 20.0 18.0 20.0 20.0 -0.810173303634997 6.784570247173055e-05 0.0005498145239267514 GO:1901136 carbohydrate derivative catabolic process biological_process 25.84419320006773 26.662468932694413 26.25739106473717 26.420043166885534 27.25376648818385 26.328034655950088 25.031834513703927 27.566751587200926 24.11555044974407 26.648498828751826 24.171575865035 26.48211934434989 25.006140596792232 26.42125431484857 26.2110235301698 26.879559899632746 24.212913577813158 26.46877471014796 27.257758134371468 26.95287662637161 25.79924928673933 26.328665278014178 24.409487130400706 26.32772684243209 25.227132776483305 26.549960510695623 87.0 75.0 92.0 77.0 64.0 143.0 44.0 113.0 51.0 107.0 60.0 79.0 70.0 100.0 51.0 109.0 113.0 115.0 74.0 85.0 48.0 81.0 65.0 105.0 8.0 7.0 6.0 7.0 6.0 7.0 5.0 7.0 8.0 7.0 5.0 7.0 7.0 7.0 6.0 7.0 7.0 7.0 7.0 7.0 5.0 6.0 6.0 6.0 -0.8182757326266845 0.003892417122778628 0.009377869824763952 GO:1901137 carbohydrate derivative biosynthetic process biological_process 30.07084713056121 30.865174728294487 30.147573916285648 30.312310348430465 29.88088370525714 30.81424151457902 29.678345174207802 31.02411758571116 29.772455525886144 30.753638770806642 30.22459492164725 30.748286008313908 30.307674373727952 30.55764640452493 30.28997584793988 31.227234551099833 29.656909409427897 31.171238360067626 30.52284332600869 31.012864678326824 30.16020010017661 30.712853370859822 29.863803859358967 31.031305290856647 30.05662728151793 30.759736805453468 699.0 750.0 683.0 917.0 758.0 1141.0 862.0 1086.0 892.0 1085.0 1019.0 844.0 922.0 1088.0 767.0 1121.0 1208.0 1193.0 914.0 924.0 928.0 1026.0 952.0 1128.0 11.0 12.0 11.0 12.0 13.0 12.0 13.0 13.0 13.0 13.0 12.0 13.0 13.0 12.0 14.0 12.0 14.0 13.0 13.0 11.0 13.0 11.0 13.0 13.0 -0.7943275977332789 4.146041132679973e-05 0.0005099643033035255 GO:1901265 nucleoside phosphate binding molecular_function 33.364345319114754 33.38116451284659 32.89261545299868 32.767860217385795 32.90383192161731 33.47673460801027 33.13684302067494 33.539707632857926 33.392776040819605 33.335718406625325 33.599519331099785 33.424988394068926 33.41689333691592 33.05022241608298 33.451058803861606 33.497764323975794 32.97303728870617 33.36338361828002 33.95456472292004 33.61342776772659 33.56977209020358 33.46426053939304 33.3364756339112 33.34336998725791 33.364717326049124 33.501210942248825 3453.0 3570.0 3244.0 4664.0 5025.0 5683.0 5997.0 5341.0 6122.0 5443.0 5960.0 4441.0 6265.0 5436.0 4644.0 5520.0 7731.0 6819.0 4292.0 4401.0 5706.0 5319.0 5720.0 5563.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.016819193731834048 0.6033317722918665 0.6716842567531217 GO:1901269 lipooligosaccharide metabolic process biological_process 23.367934873393363 24.097854325772314 23.310330225969828 22.347442646333928 23.50343112489116 24.951832795456337 22.161785032550245 23.953218166452245 23.700077354294528 23.902216172895088 23.074634287851925 23.842963278877697 23.46179647422842 24.08142551508465 23.67220730923078 24.754670297648342 22.961277429181038 24.43349268951045 23.973569475259584 23.043144776103524 22.367944208732386 24.146050052218126 23.871711775241288 24.66246373728001 23.27309046012879 22.97094623300727 12.0 10.0 10.0 40.0 16.0 16.0 26.0 16.0 20.0 16.0 28.0 12.0 20.0 26.0 16.0 16.0 34.0 24.0 8.0 20.0 26.0 16.0 20.0 18.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 -0.729919452378951 0.024343383653741054 0.04309296851045225 GO:1901292 nucleoside phosphate catabolic process biological_process 28.50038589314353 29.64465156615169 29.14724313382927 29.03116588003105 28.97596961347314 29.751048309675504 27.82874589765561 29.93285765712121 27.28297420811452 29.47733762336151 28.235389251750213 29.362460993408828 28.09495069217791 28.963442432863552 29.288610044742704 30.04113240841649 27.830759232644805 30.21208433623876 29.345427170838786 29.90310233692833 28.342166088670297 29.54779441880229 27.65992651950777 29.57370268167284 28.16428877784705 29.37721442436039 132.0 129.0 165.0 180.0 139.0 224.0 139.0 184.0 139.0 167.0 126.0 125.0 182.0 168.0 122.0 184.0 239.0 202.0 171.0 168.0 137.0 162.0 130.0 172.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 1.0 2.0 -1.1442656730081602 0.0001748865925420931 0.0008236168584623857 GO:1901293 nucleoside phosphate biosynthetic process biological_process 31.96213051305779 32.73750129697628 32.08357936202318 32.09657612428785 31.70707359654049 32.64200830756632 31.64598554112016 32.89746286007975 31.53365305078508 32.65712958693874 32.157337223322266 32.653684866375734 32.12929280075897 32.30038123185349 32.296313185228556 33.11629877562011 31.54613359039168 33.165559108329724 32.50135759650967 32.882328458416765 31.968084647817964 32.60938498313923 31.66554050712727 32.86084185407005 31.93085696526197 32.62026560827928 2161.0 2170.0 2077.0 2575.0 2379.0 3405.0 2644.0 3188.0 2740.0 3220.0 3030.0 2455.0 2933.0 3242.0 2407.0 3324.0 3610.0 3555.0 2730.0 2745.0 2831.0 3004.0 2929.0 3301.0 5.0 5.0 4.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 4.0 4.0 5.0 5.0 5.0 5.0 5.0 -0.7753707839184933 0.00010962068302139599 0.000648372570666835 GO:1901360 organic cyclic compound metabolic process biological_process 35.52432231226799 36.2746891346404 35.66123485487585 35.65888070830416 35.31955703143815 36.213297779165494 35.15489976158576 36.44376022056972 35.090905091730534 36.18683389840356 35.69462331217459 36.179266803846154 35.652015532728576 35.835031242914525 35.915511078469684 36.63153936005804 35.07048189540921 36.69046322006599 36.06503090926521 36.462386664915726 35.48020463231874 36.14407303849771 35.30248452289828 36.375951173095714 35.490341652252454 36.13988823262326 24422.0 24673.0 24000.0 29914.0 27288.0 38950.0 30762.0 36134.0 31780.0 36397.0 34367.0 28023.0 34029.0 36631.0 26904.0 37439.0 42260.0 40479.0 31150.0 30891.0 32402.0 34244.0 33010.0 36820.0 14.0 13.0 12.0 14.0 15.0 14.0 15.0 14.0 14.0 15.0 15.0 15.0 15.0 14.0 16.0 14.0 14.0 13.0 13.0 12.0 14.0 15.0 15.0 16.0 -0.7503668223724063 0.0001386794054294884 0.0007006959432226783 GO:1901361 organic cyclic compound catabolic process biological_process 29.729514171774177 29.844480128009792 29.617596872879506 29.29218858878777 29.4524825595766 29.881278810650354 29.32082398729272 30.119852579052402 29.612435532248178 29.632714886125523 29.91964552582011 29.68423069830117 29.699578175707284 29.199136893426214 30.276437156372953 30.1112804332744 29.123509760881554 30.26040039321757 30.057342363767987 30.392545181563147 28.864508218167163 29.76336967856641 30.236914404443606 29.6992371862635 29.880113937468053 29.58478639823236 243.0 223.0 281.0 315.0 320.0 373.0 415.0 320.0 419.0 328.0 390.0 245.0 455.0 292.0 290.0 297.0 501.0 466.0 333.0 266.0 388.0 256.0 372.0 306.0 6.0 4.0 6.0 5.0 8.0 6.0 8.0 6.0 6.0 5.0 7.0 6.0 7.0 4.0 5.0 5.0 7.0 6.0 8.0 5.0 6.0 4.0 6.0 5.0 -0.1149659562356149 0.4884223166225936 0.5675521891480417 GO:1901362 organic cyclic compound biosynthetic process biological_process 32.74145687522337 33.49381948305634 32.867136074872796 32.88776648979536 32.483942328406364 33.404973161136525 32.410248867771394 33.65286632301957 32.28985705963471 33.4357010504718 32.94363640698663 33.4405247012482 32.926817533264995 33.0908557070136 33.049011519185854 33.83448051598745 32.28918862121689 33.87008453030933 33.29076857961172 33.65595573482394 32.79377328902685 33.34964263785642 32.48521031367085 33.63641730332613 32.67159962306173 33.36343763002718 3806.0 3846.0 3589.0 4512.0 4215.0 5968.0 4722.0 5647.0 4837.0 5717.0 5297.0 4371.0 5207.0 5642.0 4207.0 5816.0 6560.0 6311.0 4789.0 4725.0 5004.0 5371.0 5109.0 5770.0 12.0 11.0 10.0 11.0 13.0 12.0 13.0 12.0 12.0 13.0 13.0 13.0 12.0 12.0 13.0 12.0 12.0 11.0 11.0 10.0 12.0 13.0 13.0 14.0 -0.7523626078329713 0.00010962068302139599 0.000648372570666835 GO:1901363 heterocyclic compound binding molecular_function 34.10596213879153 34.05784611570875 33.63382607284274 33.412256258790194 33.56811962832225 34.12305487140038 33.821445716610064 34.13759434856473 34.16741268068593 34.015642012839024 34.28139284522564 34.15251271755881 34.165449693708844 33.77215829521815 34.25874171111508 34.17648683345762 33.71505161921421 34.01203799632702 34.67475305954914 34.27017908849463 34.30332001360302 34.13195115056892 34.21696182804841 34.10543572875594 34.06226394931073 34.194164134456585 5408.0 5029.0 4737.0 6792.0 7180.0 7961.0 8778.0 7548.0 8825.0 7878.0 8425.0 6316.0 9340.0 7788.0 6769.0 7749.0 11035.0 9694.0 6561.0 6288.0 8337.0 7533.0 8247.0 7977.0 10.0 7.0 10.0 8.0 10.0 10.0 9.0 11.0 9.0 11.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0 11.0 0.048116023082783954 0.4529203011037244 0.5347630423627702 GO:1901440 poly(hydroxyalkanoate) metabolic process biological_process 20.94892779987655 21.633965093679148 20.511947740845187 NA NA 18.5158931782174 21.50766435959462 20.92053382460968 19.796179825362707 22.034415548187837 18.770720962218487 21.63999438030116 21.453121814529585 19.863239599653163 21.105958835398205 21.359214988795927 20.762881573076005 22.007242481819677 21.68303601250741 21.441611433187507 20.890655976049647 19.809759556234976 21.694116744666136 20.363813125047592 19.646043825971734 23.62081674159904 4.0 NA NA 2.0 6.0 4.0 2.0 4.0 2.0 4.0 4.0 2.0 6.0 4.0 2.0 4.0 4.0 4.0 2.0 4.0 2.0 4.0 2.0 6.0 2.0 NA NA 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.6850372938025977 0.490519611041511 0.5694590461207495 GO:1901505 carbohydrate derivative transmembrane transporter activity molecular_function 22.215179342047133 19.461878312097973 19.102399276209628 17.544549999226795 17.910634692485164 18.52843481138108 21.71103011239429 17.283613208054327 22.50784021198638 NA 23.69808745342524 16.042743950672442 22.75723273858896 19.939486798331124 20.711293862380792 19.68220937067257 22.436792397908594 21.186708873063587 23.07616945434949 20.2524251294587 20.22751154035075 18.9401719282035 20.799636322999014 19.54163182591796 22.972819110305306 18.6026851661491 3.0 1.0 1.0 2.0 5.0 1.0 7.0 NA 10.0 1.0 6.0 2.0 4.0 3.0 5.0 8.0 10.0 5.0 4.0 4.0 5.0 3.0 9.0 2.0 2.0 1.0 1.0 1.0 2.0 1.0 1.0 NA 4.0 1.0 2.0 1.0 3.0 1.0 1.0 2.0 2.0 3.0 3.0 2.0 2.0 2.0 4.0 2.0 2.75330102994916 0.002563516808869637 0.006910856026093958 GO:1901564 organonitrogen compound metabolic process biological_process 34.454380319914364 34.611081657491326 34.118984597561045 33.973403324234496 33.81030185891992 34.49444094472926 34.1032076129737 34.66857762623827 34.35050923337863 34.45305443014935 34.69967468703108 34.698784166028354 34.630449425787724 34.317364639092396 34.797857087406925 34.90256888287329 34.00105942527552 34.86331470907564 35.00694798927945 34.92033103507682 34.27418445416369 34.42310955860744 34.69909023659182 34.822624680591346 34.46102270404138 34.50601323179214 9595.0 9144.0 9302.0 12200.0 10965.0 14878.0 13196.0 14471.0 13549.0 14835.0 14580.0 11061.0 14797.0 14532.0 10769.0 14830.0 17324.0 16689.0 12901.0 11883.0 14087.0 13679.0 13303.0 14713.0 20.0 19.0 20.0 20.0 22.0 19.0 23.0 21.0 22.0 23.0 23.0 20.0 22.0 20.0 22.0 20.0 21.0 20.0 21.0 19.0 22.0 21.0 22.0 22.0 -0.15670133757696192 0.24821307898992373 0.31935043564889154 GO:1901565 organonitrogen compound catabolic process biological_process 29.832680222282715 28.083319971244432 28.95902854278391 27.590372117622003 28.852900504564136 27.524212391429657 29.610037687189934 28.059425107688174 30.107059340963144 27.62479613890028 30.242128697070786 28.40004801984324 29.91857992798359 27.53025286246793 30.07077119368716 26.87868780778225 29.324052604347795 26.74387664085099 30.164077977887413 30.03666645186777 28.48571885728661 28.25108165130523 30.61630825660664 26.727859603952822 30.138425299700195 27.68060686772265 170.0 132.0 243.0 203.0 291.0 242.0 438.0 245.0 433.0 220.0 427.0 175.0 408.0 166.0 272.0 140.0 481.0 453.0 306.0 179.0 383.0 113.0 385.0 236.0 9.0 7.0 11.0 9.0 13.0 9.0 12.0 13.0 11.0 12.0 11.0 9.0 12.0 9.0 12.0 9.0 12.0 12.0 14.0 9.0 10.0 8.0 12.0 10.0 1.7493602510382829 0.0001386794054294884 0.0007006959432226783 GO:1901566 organonitrogen compound biosynthetic process biological_process 32.06930265368545 32.36329536499277 31.762704891071664 31.71309002117577 31.336766807442583 32.25000602607349 31.66831393963623 32.410145642654484 31.92326965382185 32.21666894633204 32.272081790148874 32.480375784753626 32.26414537062329 32.12094231967093 32.42123984514638 32.685317251076306 31.628580822342162 32.61393233777063 32.72203490216802 32.52268660334342 32.038802123955925 32.13420710088148 32.27194094898533 32.664793220399304 31.94580815927236 32.25834227029843 1995.0 1894.0 1709.0 2473.0 2112.0 2980.0 2523.0 2949.0 2550.0 3066.0 2762.0 2253.0 2936.0 3016.0 2156.0 3100.0 3325.0 3289.0 2508.0 2375.0 2740.0 2902.0 2541.0 3005.0 15.0 14.0 12.0 14.0 16.0 14.0 17.0 14.0 16.0 16.0 17.0 15.0 17.0 14.0 16.0 14.0 15.0 14.0 14.0 12.0 16.0 16.0 16.0 16.0 -0.2939927113073253 0.0734883472918226 0.11239394291690516 GO:1901575 organic substance catabolic process biological_process 31.73686287393056 31.70438279329317 31.565922768565322 31.18608579549479 31.535758503455558 31.75474883057828 31.34561131976293 31.953071372402096 31.61896105896729 31.4457092595008 31.903724920471788 31.57745922315041 31.70348785563357 31.113179477847115 32.18419655924778 31.93918190511892 31.10059472667777 31.99690267158302 32.339229147190075 32.374839760171966 31.015742981141358 31.666398101344534 32.09552718679629 31.49974320366972 31.7991906547823 31.431833409803065 1094.0 985.0 1337.0 1311.0 1325.0 1602.0 1611.0 1347.0 1672.0 1395.0 1655.0 1042.0 1834.0 1299.0 1184.0 1217.0 2278.0 1946.0 1453.0 1177.0 1512.0 1036.0 1501.0 1336.0 9.0 10.0 10.0 11.0 10.0 10.0 11.0 10.0 11.0 11.0 10.0 10.0 11.0 10.0 10.0 11.0 11.0 11.0 10.0 10.0 10.0 11.0 10.0 11.0 0.03248008063738794 0.9080725552559752 0.9266349541778063 GO:1901576 organic substance biosynthetic process biological_process 34.38457180083377 34.94776649086364 34.32912861443344 34.293343216605344 33.93149181355916 34.82755901079568 34.02042067915438 35.07805049603526 34.1054455083013 34.882436350139926 34.568259988593525 34.96678201997613 34.571235143351934 34.597855069145545 34.704696157727675 35.28414665415242 33.95405383979889 35.29001543976131 34.975689255824506 35.1114065263022 34.39653526261661 34.77165246595599 34.35171044198409 35.120849238958826 34.31002184686758 34.84849600756661 11181.0 10938.0 10178.0 13400.0 12253.0 17282.0 14060.0 16503.0 14480.0 16917.0 15711.0 12876.0 15785.0 16737.0 12368.0 17216.0 19389.0 18603.0 14051.0 13674.0 15039.0 15892.0 14899.0 16918.0 13.0 12.0 12.0 14.0 14.0 14.0 14.0 13.0 14.0 14.0 14.0 14.0 14.0 14.0 14.0 14.0 14.0 13.0 14.0 13.0 14.0 14.0 14.0 15.0 -0.5631946900298743 0.0009986863791802587 0.0031633517797384847 GO:1901605 alpha-amino acid metabolic process biological_process 31.006419077582976 30.67537463573079 30.629222983329434 29.840611609516806 30.59194622008984 30.49017318702573 30.808064932655235 30.525560390213627 30.904967747138954 30.30315141628603 31.295756905778703 31.04005784615322 31.133765284459077 30.457118892608843 31.224211718623103 31.00034454815856 30.5212851542272 30.984406640195175 31.457066972271715 30.95322413102085 30.59676770051439 30.51358777568089 31.314183391867147 31.068362553634444 31.179088472164178 30.40257187887561 837.0 973.0 1154.0 1387.0 1007.0 1630.0 1117.0 1517.0 1383.0 1627.0 1446.0 1252.0 1326.0 1632.0 919.0 1768.0 1704.0 1650.0 1384.0 1303.0 1429.0 1602.0 1233.0 1556.0 15.0 14.0 12.0 13.0 15.0 15.0 16.0 14.0 15.0 16.0 17.0 16.0 17.0 14.0 15.0 16.0 16.0 15.0 14.0 14.0 15.0 16.0 15.0 15.0 0.3310444418521854 0.017926339076638688 0.03379466943753034 GO:1901606 alpha-amino acid catabolic process biological_process 28.46589834241823 26.51974739315752 28.051459750148968 26.02718754835373 28.03129702005147 26.697596252070195 28.117642808357438 26.788729345217124 28.62737415282061 26.046552576583338 28.812377581979064 27.1361825494176 28.46848464017713 25.81481636696112 28.723882493648905 25.554728033888203 27.90222475155797 25.661317887303905 28.867780698069247 27.912358531723466 27.3961597690256 27.21917793971439 29.07135990996624 22.89402192528243 28.65631452281808 25.98844158176542 46.0 33.0 112.0 88.0 99.0 68.0 137.0 49.0 155.0 56.0 131.0 45.0 129.0 37.0 81.0 36.0 183.0 122.0 117.0 45.0 134.0 21.0 118.0 53.0 6.0 5.0 5.0 4.0 6.0 5.0 6.0 5.0 7.0 6.0 6.0 7.0 6.0 4.0 7.0 5.0 6.0 6.0 5.0 5.0 6.0 5.0 5.0 7.0 1.946150949260712 5.312128159411724e-05 0.0005099643033035255 GO:1901607 alpha-amino acid biosynthetic process biological_process 27.462655353290163 28.88322490341105 27.53422427501639 27.88226176650973 27.382063403960924 28.54909869412611 27.393474034175835 28.577975175346218 27.032705997890005 28.54532611109537 27.54611342999616 29.174208907882978 27.761754594138818 28.66517389045061 27.927388666791177 29.466452592702133 26.93549660863239 29.49898837694273 27.78270904022125 28.68496420859905 27.23389916636589 28.29313410534104 27.326932226219164 29.60196652509234 27.36126044166318 28.581283215129233 227.0 298.0 258.0 376.0 194.0 470.0 190.0 472.0 264.0 490.0 313.0 377.0 285.0 541.0 197.0 587.0 339.0 418.0 309.0 409.0 308.0 541.0 255.0 477.0 9.0 11.0 9.0 10.0 10.0 11.0 10.0 9.0 10.0 11.0 13.0 12.0 10.0 10.0 9.0 12.0 10.0 11.0 9.0 10.0 9.0 12.0 9.0 11.0 -1.420569550120888 4.146041132679973e-05 0.0005099643033035255 GO:1901615 organic hydroxy compound metabolic process biological_process 28.847171380715512 28.68433789436988 28.048960099101702 28.22619823783492 29.00643803875845 28.55671794265276 28.269696565580148 27.799243631547146 28.35413547074605 28.24232667497201 28.699195457958673 28.610423715744766 28.962651825629568 27.98653918352981 28.026113801920534 28.743705034871077 26.807655874775076 28.36544305979937 30.725693643189878 30.321996679198904 29.497286823250064 28.380164719912834 27.751807238958435 28.490886571440143 27.589218809613598 28.48821311465714 156.0 134.0 189.0 199.0 234.0 176.0 232.0 132.0 250.0 242.0 277.0 141.0 238.0 207.0 160.0 185.0 492.0 306.0 289.0 169.0 239.0 158.0 231.0 173.0 4.0 6.0 5.0 6.0 6.0 6.0 4.0 5.0 7.0 6.0 6.0 6.0 6.0 6.0 5.0 7.0 6.0 6.0 7.0 5.0 7.0 7.0 7.0 7.0 0.1628334863456331 0.7728299926844475 0.8146045868836069 GO:1901617 organic hydroxy compound biosynthetic process biological_process 22.18222665475585 21.394206563100305 19.006307529898237 17.82753091839228 20.770252932454255 21.793795527968207 21.36075991492734 19.314828188412708 23.44993533666429 17.87587046230609 23.06923711466238 20.430799773828486 22.36900019463204 22.862258160336925 21.14273784745593 22.708907557807088 21.516589638100136 22.651827465334325 21.976455479308047 15.307756453769901 21.860775417225064 19.812397036392483 22.106990938576 21.798381444948593 23.045297239834515 20.21837631885045 1.0 2.0 3.0 7.0 7.0 2.0 3.0 2.0 9.0 5.0 10.0 4.0 4.0 14.0 6.0 11.0 16.0 1.0 9.0 3.0 10.0 13.0 10.0 5.0 1.0 2.0 1.0 2.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 3.0 2.0 3.0 2.0 3.0 3.0 1.0 2.0 1.0 2.0 3.0 2.0 3.0 0.7880200916555467 0.0734883472918226 0.11239394291690516 GO:1901654 response to ketone biological_process 18.696578774088376 21.95376802813304 17.041541616741096 21.215515926602414 14.802535732482758 21.4531044018516 16.19463320873981 21.85520971241421 19.39669951353797 21.843828761187762 20.7637050754652 22.70712252864921 14.889243061109436 20.724190290592045 NA 21.445661817994075 18.0178046006368 23.32709062988541 18.161380949769033 22.189294848181486 NA 19.599950495276754 19.61272291913899 22.935393263326787 17.183086880705268 18.301723201613555 2.0 6.0 2.0 2.0 2.0 6.0 4.0 2.0 4.0 8.0 2.0 8.0 NA 4.0 4.0 8.0 4.0 6.0 NA 2.0 4.0 12.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 2.0 -3.2571892540446648 0.00036993149163163074 0.0014703009603703032 GO:1901657 glycosyl compound metabolic process biological_process 29.13359693834289 30.220459461497413 29.438793634611397 30.21036813304872 29.69782742234881 30.231243836697306 28.411368898407755 30.238692029545145 28.261435411780766 29.944064120317 28.75661346225713 29.907558890556835 29.609042285910874 30.322842553715077 28.705688281715034 30.233971395349464 28.532885200209822 29.9897876397315 29.225706297861052 30.646124153797132 29.64301019988019 30.010095672309518 29.35575622043039 30.460390226200882 29.004318652402066 30.26651278446962 638.0 653.0 736.0 942.0 525.0 1062.0 692.0 1052.0 665.0 965.0 878.0 768.0 684.0 1015.0 519.0 1048.0 946.0 929.0 910.0 891.0 777.0 921.0 658.0 1114.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 -1.0868625231545224 3.225641456243767e-05 0.0005099643033035255 GO:1901661 quinone metabolic process biological_process 21.788722191894614 20.045488714739143 18.630970607046283 NA NA 18.873079419607834 18.192466725346247 19.937654237671946 18.487930719377765 20.96108201000024 20.37637774262498 18.198266334910013 21.053079998986565 NA 20.6569573375984 19.12224208288778 22.4845371876197 19.64460347339713 23.59370439044444 20.171102286161002 21.49366886358077 15.91632143682514 23.008309479130965 NA 21.80776753743163 21.64539452036062 2.0 NA NA 4.0 2.0 4.0 2.0 4.0 6.0 2.0 4.0 NA 2.0 4.0 4.0 2.0 40.0 4.0 4.0 2.0 8.0 NA 6.0 8.0 2.0 NA NA 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 NA 2.0 2.0 1.7432334771554707 0.10237755581065076 0.14926073557440672 GO:1901681 sulfur compound binding molecular_function 27.94060901277379 26.84514302655435 24.67954341198089 21.64935379911028 19.925404490256547 21.79371343193319 28.13977750978106 26.836421605980235 28.75861686292162 27.970562760345093 28.661695126913823 26.935277494530066 28.271871755658 25.82764491098392 28.82957181096709 26.29171795841005 28.52389324075067 26.871285277965878 26.732750569199023 26.97166949279191 25.94454487294532 26.14907731060064 27.740521098654714 25.37486627046805 28.167229919479084 28.627124128924322 23.0 9.0 5.0 4.0 80.0 44.0 99.0 60.0 98.0 44.0 92.0 44.0 111.0 47.0 81.0 43.0 78.0 69.0 50.0 40.0 85.0 49.0 94.0 58.0 3.0 2.0 3.0 1.0 3.0 3.0 2.0 5.0 2.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 4.0 3.0 4.0 3.0 3.0 4.0 3.0 4.0 1.0954659862194411 0.0832645166635504 0.12534875367444018 GO:1901700 response to oxygen-containing compound biological_process 23.13871365749278 23.15974307412606 18.754253078196754 22.215515926602418 21.946648850332775 22.83495120351216 22.579727806998417 22.94631214183115 23.382352020107714 22.843828761187762 24.09853576415607 23.711402278056088 23.0339753971375 22.15739388851533 22.99051063585103 22.64368231374184 23.31856792137649 24.53024461511097 23.962531699722714 23.94524796306974 19.80355701238731 20.599950495276754 23.022727009750966 24.010905795978772 24.10187815706314 19.301723201613555 6.0 12.0 9.0 6.0 14.0 15.0 23.0 4.0 23.0 17.0 14.0 20.0 10.0 11.0 21.0 24.0 39.0 28.0 2.0 4.0 20.0 27.0 18.0 4.0 3.0 2.0 3.0 3.0 3.0 3.0 3.0 2.0 3.0 3.0 3.0 3.0 1.0 3.0 3.0 3.0 6.0 3.0 1.0 2.0 3.0 3.0 3.0 2.0 -0.021029416633279396 0.6861059569955559 0.7413508522341591 GO:1902494 catalytic complex cellular_component 27.69673496271822 28.409158899278818 27.633704048872623 27.842986257311047 28.28003733325047 28.249769154114198 27.34937172651988 27.967001233945336 26.84104673574512 27.87362220708837 27.56408239794973 28.58813422133363 27.839293839175127 28.40877764736821 28.202116605661512 28.78518168837457 27.25081549032847 28.913645605712446 27.73299123833103 28.136270634114783 28.07117245460321 28.550489291568752 27.443106305205145 28.97334692112721 27.5051718788554 27.98625986626663 113.0 110.0 130.0 152.0 115.0 176.0 145.0 149.0 158.0 162.0 152.0 123.0 136.0 151.0 118.0 149.0 205.0 171.0 136.0 134.0 152.0 153.0 178.0 163.0 9.0 8.0 9.0 10.0 12.0 9.0 12.0 8.0 16.0 10.0 15.0 9.0 10.0 12.0 12.0 12.0 15.0 13.0 10.0 8.0 13.0 8.0 13.0 12.0 -0.7124239365605973 0.0009986863791802587 0.0031633517797384847 GO:1902600 proton transmembrane transport biological_process 27.340726834609946 28.224060014914155 27.03622545192765 27.44807379490663 26.6795178674373 28.043584082488394 26.976981792888733 28.266775033189397 27.15247461699676 28.185933912617326 27.441852946052947 28.32447238402756 27.465528515342694 27.712878728866862 27.0752035806874 28.69734740606059 27.04661781360156 28.60311847760572 28.022091940626375 28.196146029729896 27.873308698834066 28.095688723106843 27.423018366253423 28.35223798319982 27.31717185555133 28.333120871733946 105.0 96.0 98.0 127.0 106.0 135.0 130.0 136.0 123.0 137.0 126.0 98.0 132.0 131.0 92.0 132.0 140.0 155.0 128.0 126.0 125.0 104.0 124.0 149.0 1.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 2.0 -0.8833331803042093 0.00010962068302139599 0.000648372570666835 GO:1903506 regulation of nucleic acid-templated transcription biological_process 26.261466006474684 27.602221492088752 26.61390944146384 27.246863045324698 26.83617028674657 27.02678246472542 25.370185617263125 27.907601159183177 26.248904917288225 27.990909003362376 26.11183419784016 27.745333974144746 26.316330188308626 27.35506986419443 25.97585598865756 27.584971107848645 25.058513203782702 27.568758968606854 26.930521999631978 28.106234496800777 26.535940466703806 27.209010543180533 25.776290603674926 27.381614918006434 26.253397023575715 27.676009877613392 97.0 122.0 90.0 115.0 94.0 163.0 90.0 164.0 123.0 141.0 131.0 146.0 104.0 140.0 82.0 148.0 187.0 176.0 115.0 111.0 85.0 151.0 127.0 164.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.3407554856140678 3.225641456243767e-05 0.0005099643033035255 GO:1903509 liposaccharide metabolic process biological_process 23.89586206481017 24.203704993734327 23.36069348767145 22.465628436424712 23.50343112489116 25.00653208378613 22.93077536651537 24.04657070794505 23.880576463615746 24.03794753513056 23.70922199805728 24.007249950004002 24.21134789465896 24.193505611212693 23.93081391934911 24.772331636512646 23.77491290581069 24.492545859403855 25.02824805609149 23.55522202487975 23.13889555765839 24.199758769861962 24.144393003687163 24.73017253786458 23.906265768066746 23.2642100212525 13.0 12.0 10.0 47.0 22.0 19.0 33.0 19.0 30.0 19.0 40.0 15.0 25.0 28.0 29.0 19.0 49.0 34.0 17.0 22.0 34.0 18.0 30.0 21.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -0.3078429289241562 0.14891467317876572 0.20512749682902828 GO:1904680 peptide transmembrane transporter activity molecular_function 21.880935083135068 20.34901957527381 19.98092163024805 NA 16.47524409615321 21.429909813477718 21.12600413531054 15.19266807537262 21.702515600794573 19.157932928507066 22.708581815604855 21.037246978088746 22.507476909016948 NA 20.19855760319903 20.367464025193605 22.11632312931727 20.1746064018943 21.730667307832604 19.361259237882162 21.4604228492312 NA 21.875936474617824 20.31593387920136 23.356020098423944 20.861763148400406 5.0 NA 1.0 11.0 3.0 2.0 2.0 4.0 3.0 5.0 6.0 NA 4.0 8.0 5.0 11.0 6.0 4.0 1.0 NA 6.0 4.0 5.0 4.0 1.0 NA 1.0 1.0 2.0 1.0 1.0 1.0 2.0 1.0 2.0 NA 2.0 1.0 2.0 2.0 3.0 3.0 1.0 NA 3.0 1.0 2.0 1.0 1.5319155078612567 0.015680223059080796 0.030292443309183948 GO:1990077 primosome complex cellular_component 20.74932325001456 21.615397374971213 21.283621213238945 21.440293587879776 21.276390670831336 22.68449022500184 20.493954721259943 20.87862696983612 19.717243849686625 21.002926996763847 21.33893598789482 22.453270610822255 21.85930162674964 22.13314409665805 21.315122445408573 20.95267978657981 15.532618974349509 20.19636667392378 19.083143107707347 21.17291123043827 20.97059717095305 21.213308922587146 19.29881658735413 22.323284877500896 20.36639628911957 20.3333311985342 7.0 10.0 3.0 12.0 3.0 9.0 5.0 12.0 9.0 11.0 10.0 13.0 6.0 13.0 2.0 6.0 7.0 14.0 6.0 6.0 4.0 12.0 8.0 6.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -0.8660741249566541 0.10596880912720232 0.15148805703407617 GO:1990204 oxidoreductase complex cellular_component 24.778483582099923 24.42305549142528 22.742545217867107 23.81800952299552 22.45466560827657 24.64427342242311 24.48686865392953 24.687751984364446 22.249493345228625 24.183403886683998 24.379373984010247 24.249185033680572 25.86592723294292 23.888895735722212 26.32195788729597 24.279804545853573 23.80275333152324 24.417370924623107 25.63021236022171 24.67525355309725 24.62614212966295 24.102477540853343 24.333298710001262 25.09616415049825 24.49303704852603 24.512090862638445 18.0 16.0 18.0 30.0 19.0 23.0 14.0 20.0 21.0 28.0 19.0 13.0 16.0 18.0 19.0 27.0 44.0 33.0 25.0 15.0 17.0 24.0 24.0 20.0 5.0 3.0 3.0 4.0 6.0 4.0 4.0 4.0 6.0 5.0 5.0 2.0 6.0 2.0 6.0 2.0 6.0 7.0 4.0 3.0 6.0 3.0 7.0 5.0 0.35542809067464276 0.9080725552559752 0.9266349541778063 GO:1990234 transferase complex cellular_component 21.51930742022045 20.39378602639632 19.67157906926099 20.221073388061573 21.685305931164326 20.78162746059115 20.984347373435664 20.10256340652164 21.410711924314448 19.401685322834272 21.522570616839236 20.691127753343128 21.683341069761795 20.36470794167372 20.262632317232708 18.38022937137946 20.36826190524152 16.030960684955588 22.18951928343387 19.311160080373817 22.830183165565657 21.325688707708462 21.6169256337846 20.97465453356789 21.282873430607726 21.466606081370358 4.0 4.0 5.0 8.0 6.0 5.0 8.0 3.0 9.0 5.0 10.0 4.0 8.0 3.0 5.0 3.0 9.0 2.0 13.0 3.0 8.0 5.0 8.0 5.0 3.0 2.0 2.0 2.0 3.0 1.0 3.0 1.0 4.0 2.0 2.0 1.0 3.0 1.0 3.0 1.0 2.0 2.0 2.0 2.0 2.0 1.0 3.0 2.0 1.1255213938241297 0.005583616806378765 0.012692811975156102 GO:1990391 DNA repair complex cellular_component 21.008296706000213 21.42270767877527 21.582548229280626 20.446663020869398 21.24904270714061 21.69432529765836 22.22183106947669 20.703200500147762 20.6833021979932 19.800035966944534 21.4329554256292 22.040603367708766 21.469908559630614 22.070348182322718 18.91268764690865 21.684545718909845 19.92275544117182 20.881937731851487 20.491550979575702 21.23605754095537 18.238787894898586 19.4999168238156 19.797476219032426 22.69065042497588 21.602842006467146 21.126188576389247 9.0 6.0 12.0 11.0 3.0 9.0 12.0 7.0 13.0 14.0 8.0 14.0 4.0 13.0 6.0 13.0 8.0 10.0 4.0 4.0 7.0 21.0 15.0 9.0 2.0 2.0 1.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 1.0 2.0 1.0 1.0 2.0 2.0 2.0 2.0 -0.4144109727750589 0.3263484733220724 0.4012639356708831 GO:1990904 ribonucleoprotein complex cellular_component 31.165174607741903 31.14676489233345 30.71943595818891 30.595777770854358 30.46689133510265 31.159212269797802 30.709044243523746 31.22336687590519 31.45398911075231 30.985615973218394 31.2805160878864 31.309417118309817 31.297841103364558 31.135315690327463 31.641888781670236 31.305101613346572 30.763074158539265 30.97577557393039 31.35148776755681 31.334350901359077 31.041424502879767 31.02723226028721 31.681530691077203 31.43813399129893 30.98900024701669 31.089557735886906 518.0 270.0 367.0 556.0 611.0 500.0 787.0 446.0 711.0 532.0 666.0 323.0 932.0 443.0 596.0 403.0 746.0 668.0 659.0 371.0 750.0 376.0 653.0 533.0 4.0 3.0 5.0 3.0 4.0 5.0 4.0 4.0 5.0 4.0 4.0 5.0 3.0 5.0 5.0 5.0 4.0 7.0 2.0 4.0 4.0 4.0 5.0 5.0 0.018409715408452598 0.9539596927720386 0.9577970205788449 GO:2000112 regulation of cellular macromolecule biosynthetic process biological_process 28.079891651623925 28.79020209783552 28.26915640698684 28.40919311526568 28.304349960869413 28.72065470341578 27.703615179375 29.07974724242657 27.72573130808365 28.94447930691111 27.98123342119566 28.925853440725582 28.07032745076713 28.64378840898086 28.0412330956282 28.717095722191754 27.542977117183128 28.691346823804523 28.63541965303673 29.176557487722892 28.259425342329425 28.54524587548893 27.939341483560987 28.581495264653373 28.135415728928514 28.84866809360601 163.0 179.0 156.0 192.0 165.0 248.0 167.0 246.0 214.0 241.0 214.0 211.0 177.0 228.0 150.0 232.0 325.0 268.0 198.0 176.0 162.0 231.0 211.0 261.0 3.0 3.0 3.0 3.0 4.0 3.0 3.0 3.0 4.0 4.0 4.0 3.0 3.0 3.0 4.0 3.0 4.0 3.0 4.0 3.0 4.0 4.0 4.0 4.0 -0.7103104462115972 6.784570247173055e-05 0.0005498145239267514 GO:2000113 negative regulation of cellular macromolecule biosynthetic process biological_process 22.60266741107676 22.236837972385544 21.30030518237217 22.047478426541858 23.27970856165999 21.464966997040502 22.68300308242573 21.403375515281333 20.941315544901308 23.20906481771488 23.110740747879433 21.78461252223164 23.234225562341464 22.03786639857234 21.433366644229807 20.233594686557442 21.522695545358385 21.07809661598035 22.89397308126998 23.721564622589497 23.42759588328258 21.680974100515922 22.096908708542376 21.55145677527049 22.65052395817018 22.92760386629374 10.0 13.0 15.0 7.0 14.0 13.0 11.0 17.0 16.0 11.0 21.0 11.0 7.0 8.0 7.0 11.0 20.0 22.0 17.0 13.0 10.0 11.0 17.0 21.0 1.0 2.0 2.0 1.0 3.0 1.0 2.0 1.0 3.0 3.0 3.0 2.0 1.0 1.0 3.0 1.0 3.0 1.0 2.0 2.0 3.0 2.0 2.0 2.0 0.36582943869121465 0.3263484733220724 0.4012639356708831 GO:2001059 D-tagatose 6-phosphate catabolic process biological_process 23.51165622291565 24.98449088822721 24.58628517759067 24.912876342135274 25.061871229539328 24.283061735179054 23.405696302068467 25.63328576980955 17.829756253830322 25.040481875405426 19.691261902405127 25.311348757482648 22.648951316398268 25.07592700325359 24.957240657266393 25.395341204296265 22.223531971764206 24.759006753308693 24.25004185139378 24.47573296436818 21.889494052794266 24.7374192095463 19.94916118927913 24.89935198902975 21.075907601073208 24.721609809672685 27.0 33.0 30.0 28.0 12.0 42.0 2.0 36.0 5.0 36.0 11.0 23.0 26.0 38.0 12.0 41.0 23.0 30.0 10.0 34.0 4.0 27.0 10.0 33.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA -1.4728346653115594 0.0014961642897455532 0.004424675435076897 GO:2001141 regulation of RNA biosynthetic process biological_process 26.34205256788306 27.63543530743977 26.651512126434774 27.28352201899168 26.948655423347926 27.05700592789492 25.51291335182695 27.923407315980626 26.27982855783693 28.042422307734395 26.20815926277268 27.76388853668417 26.412683613973734 27.38663485129848 26.03647283004182 27.59377882498742 25.126784640686463 27.58471360291358 26.947624030309463 28.17369718937304 26.68520714216416 27.23792387977294 25.86321781865529 27.403800793482624 26.354142491094432 27.72650496536477 108.0 134.0 103.0 122.0 105.0 176.0 99.0 181.0 134.0 150.0 147.0 155.0 111.0 148.0 87.0 159.0 195.0 198.0 131.0 123.0 93.0 161.0 142.0 184.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 3.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 -1.2933827395567121 3.225641456243767e-05 0.0005099643033035255 GO:2001295 malonyl-CoA biosynthetic process biological_process 24.04176718902617 23.368503914625965 21.869190774106308 22.091623247786497 22.35226996419096 23.63067388937766 23.95004243777072 23.42842882120955 24.81066402548795 22.34498269235208 24.884545910598035 22.333495223933372 24.3377404391613 23.13908510884377 23.65652105389825 24.35531641248085 24.302973205450648 23.68292928714755 23.659012427821196 23.030970680176765 23.41822612657516 23.591034950731125 23.797385759933352 24.254723130459904 24.70188938490118 22.31230963978653 7.0 11.0 16.0 15.0 21.0 21.0 23.0 11.0 24.0 15.0 24.0 8.0 22.0 24.0 13.0 19.0 25.0 23.0 16.0 20.0 18.0 16.0 23.0 13.0 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 0.6732632744002061 0.04964722965745621 0.07872902492059129