Mercurial > repos > galaxyp > msstatstmt
view test-data/evidence.txt @ 0:fd3dc69b78ff draft
"planemo upload for repository https://github.com/galaxyproteomics/tools-galaxyp/tree/master/tools/msstatstmt commit 7c5032273bfe66383e072457aeea888917f7ebed"
author | galaxyp |
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date | Sun, 24 Jan 2021 16:40:12 +0000 |
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Sequence Length Modifications Modified sequence Arg10 Probabilities Lys8 Probabilities Lys8+TMT6 Probabilities Oxidation (M) Probabilities Arg10 Score Diffs Lys8 Score Diffs Lys8+TMT6 Score Diffs Oxidation (M) Score Diffs Arg10 Lys8 Lys8+TMT6 Oxidation (M) Missed cleavages Proteins Leading proteins Leading razor protein Gene names Protein names Type Raw file Experiment MS/MS m/z Charge m/z Mass Resolution Uncalibrated - Calibrated m/z [ppm] Uncalibrated - Calibrated m/z [Da] Mass Error [ppm] Mass Error [Da] Uncalibrated Mass Error [ppm] Uncalibrated Mass Error [Da] Max intensity m/z 0 Retention time Retention length Calibrated retention time Calibrated retention time start Calibrated retention time finish Retention time calibration Match time difference Match m/z difference Match q-value Match score Number of data points Number of scans Number of isotopic peaks PIF Fraction of total spectrum Base peak fraction PEP MS/MS Count MS/MS Scan Number Score Delta score Combinatorics Intensity Reporter intensity corrected 0 Reporter intensity corrected 1 Reporter intensity corrected 2 Reporter intensity corrected 3 Reporter intensity corrected 4 Reporter intensity corrected 5 Reporter intensity corrected 6 Reporter intensity corrected 7 Reporter intensity corrected 8 Reporter intensity corrected 9 Reporter intensity 0 Reporter intensity 1 Reporter intensity 2 Reporter intensity 3 Reporter intensity 4 Reporter intensity 5 Reporter intensity 6 Reporter intensity 7 Reporter intensity 8 Reporter intensity 9 Reporter intensity count 0 Reporter intensity count 1 Reporter intensity count 2 Reporter intensity count 3 Reporter intensity count 4 Reporter intensity count 5 Reporter intensity count 6 Reporter intensity count 7 Reporter intensity count 8 Reporter intensity count 9 Reporter PIF Reporter fraction Reverse Potential contaminant id Protein group IDs Peptide ID Mod. peptide ID MS/MS IDs Best MS/MS AIF MS/MS IDs Arg10 site IDs Lys8 site IDs Lys8+TMT6 site IDs Oxidation (M) site IDs AAANFSDR 8 Arg10 _AAANFSDR(ar)_ AAANFSDR(1) AAANFSDR(66.96) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_03 M4R3 545.79 2 431.208076 860.401598 85067.94 0.79511 0.00034286 265720 114.58 265720 114.58 545.789495303649 49.598 0.42772 49.598 49.373 49.801 0 16 10 2 0.469855487346649 0.000767308170907199 0.023196829482913 0.042982 1 20152 66.962 22.845 1 6851100 2118.6 2269.9 1982.4 1761.8 2145.1 2072.2 2421.1 2571 1797.2 2288.5 1992.9 2146.1 2001.8 1837.5 2195.6 2092.3 2437.3 2529.5 1807.2 2277 1 1 1 1 1 1 1 1 1 1 241 18 31 31 245 245 31 AAANFSDR 8 Arg10 _AAANFSDR(ar)_ AAANFSDR(1) AAANFSDR(88.37) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 545.7897 2 431.208076 860.401598 83670.9 0.66409 0.00028636 265720 114.58 265720 114.58 545.789482528973 48.985 0.62196 48.985 48.668 49.29 0 30 17 3 0.838059902191162 0.00133275322150439 0.0186835266649723 0.0065304 1 20598 88.37 52.925 1 3845700 440.95 451.5 731.09 480.91 781.02 528.87 494.97 603.61 434.65 593.29 416.59 427.4 716.2 491.98 795.16 534.4 513.05 596.05 434.54 588.65 1 1 1 1 1 1 1 1 1 1 242 18 31 31 246 246 31 AIVQQWLEYR 10 Arg10 _AIVQQWLEYR(ar)_ AIVQQWLEYR(1) AIVQQWLEYR(82.49) 1 0 0 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 772.9348 2 658.355271 1314.69599 NaN NaN NaN NaN NaN NaN NaN NaN 165.8 1 165.8 165.3 166.3 0 NaN NaN NaN 0.012752 1 84632 82.494 27.033 1 751.04 750.39 738.84 961.03 809.28 779.15 1117.5 999.37 735.79 918.49 706.71 710.95 743.62 972.83 830.35 797.05 1116.3 982.92 743.38 913.02 1 1 1 1 1 1 1 1 1 1 10484 278 1422 1488 10799 10799 812 AIVQQWLEYR 10 Arg10 _AIVQQWLEYR(ar)_ AIVQQWLEYR(1) AIVQQWLEYR(91.7) 1 0 0 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 772.936 2 658.355271 1314.69599 68746.85 1.3159 0.00086634 174040 114.58 174040 114.58 772.935757796515 164.72 0.96715 164.72 164.47 165.43 0 26 20 2 0.256266713142395 0.000511677586473525 0.0109192887321115 0.0025695 1 86299 91.701 47.384 1 56988000 535.55 533.74 752.36 723.35 776.62 784.56 757.64 564.96 736.98 723.88 505.2 505.84 742.16 731.84 795.51 788.57 769.64 569.3 734.52 713.67 1 1 1 1 1 1 1 1 1 1 10485 278 1422 1488 10800 10800 812 AIVQQWLEYR 10 Arg10 _AIVQQWLEYR(ar)_ AIVQQWLEYR(1) AIVQQWLEYR(102.53) 1 0 0 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_01 M3R1 772.9371 2 658.355271 1314.69599 70452.55 1.1597 0.0007635 174040 114.58 174040 114.58 772.935568154707 165.02 0.65088 165.02 164.74 165.39 0 29 13 3 0.756889820098877 0.0014602382434532 0.0324378795921803 0.00088775 1 87302 102.53 62.473 1 38081000 346.3 513.45 396.09 283.84 339.52 659.49 467.81 401.94 398.46 371.91 326.17 485.03 394.47 306.44 353.5 650.66 468.73 405.71 398.75 369.62 1 1 1 1 1 1 1 1 1 1 10486 278 1422 1488 10801 10801 812 AIVQQWLEYR 10 Arg10 _AIVQQWLEYR(ar)_ AIVQQWLEYR(1) AIVQQWLEYR(112.83) 1 0 0 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_02 M4R2 772.9361 2 658.355271 1314.69599 68766.42 1.0212 0.00067229 174040 114.58 174040 114.58 772.93540303078 164.38 0.42207 164.38 164.24 164.66 0 26 8 4 0.699990928173065 0.00168229290284216 0.0215743128210306 0.00040767 1 85219 112.83 62.029 1 42583000 284.12 332.68 441.81 286.53 559.89 403.37 279.85 468.99 504.02 394.12 268.26 314.66 434.45 297.26 564.17 404.89 298.81 461.79 495.7 392.83 1 1 1 1 1 1 1 1 1 1 10487 278 1422 1488 10802 10802 812 AIVQQWLEYR 10 Arg10 _AIVQQWLEYR(ar)_ AIVQQWLEYR(1) AIVQQWLEYR(65.84) 1 0 0 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_03 M4R3 772.935 2 658.355271 1314.69599 70324.12 1.4645 0.00096413 174040 114.58 174040 114.58 772.935923369425 164.32 0.46277 164.32 164.1 164.56 0 20 9 3 0.289184600114822 0.000433021661592647 0.00871592853218317 0.036193 1 86505 65.842 18.962 1 59370000 855.38 796.36 626.6 527.18 913.44 945.67 599.11 585.88 692.16 659.23 803.68 752.61 646.04 558.54 916.56 937.43 622.29 592.82 686.73 651.82 1 1 1 1 1 1 1 1 1 1 10488 278 1422 1488 10803 10803 812 AIVQQWLEYR 10 Arg10 _AIVQQWLEYR(ar)_ AIVQQWLEYR(1) AIVQQWLEYR(68.13) 1 0 0 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 773.4396 2 658.355271 1314.69599 71827.64 0.99973 0.00065817 174040 114.58 174040 114.58 772.935941121258 163.14 0.50685 163.14 163.01 163.51 0 22 10 3 0.723028600215912 0.000635053380392492 0.00261190696619451 0.029695 1 87702 68.132 34.242 1 103770000 336.83 275.6 403.55 337.73 179.08 420.96 580.87 583.81 481.26 479.99 317.35 261.05 399.92 343.53 202.26 425.17 572.09 572.25 482.05 478.76 1 1 1 1 1 1 1 1 1 1 10489 278 1422 1488 10804 10804 812 ASQQEIQHIVNR 12 Arg10 _ASQQEIQHIVNR(ar)_ ASQQEIQHIVNR(1) ASQQEIQHIVNR(62.69) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 554.6443 3 478.255874 1431.74579 NaN NaN NaN NaN NaN NaN NaN NaN 73.105 1 73.105 72.605 73.605 0 NaN NaN NaN 0.029343 1 31943 62.694 32.889 1 368.39 515.99 328.2 543.55 520.73 415.54 419.92 526.49 613.02 484.54 346.45 488.42 333.49 555.15 521.75 426 433.36 517.99 605.12 481.63 1 1 1 1 1 1 1 1 1 1 19061 18 2579 2699 19694 19694 32 AYGSPWCNK 9 Lys8+TMT6 _AYGSPWCNK(ly)_ AYGSPWCNK(1) AYGSPWCNK(88.5) 0 0 1 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_01 M3R1 774.9091 2 660.328399 1318.64225 NaN NaN NaN NaN NaN NaN NaN NaN 109.6 1 109.6 109.1 110.1 0 NaN NaN NaN 0.0087754 1 55249 88.495 12.987 1 408.25 453.51 509.56 283.82 463.15 374.83 482.56 547.53 391.38 544.91 384.75 428.53 505.23 301.17 478.43 378.71 487.73 537.65 392.31 540.46 1 1 1 1 1 1 1 1 1 1 23639 18 3178 3334 24437 24437 49 AYGSPWCNK 9 Lys8+TMT6 _AYGSPWCNK(ly)_ AYGSPWCNK(1) AYGSPWCNK(89.03) 0 0 1 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_02 M5R2 774.9104 2 660.328399 1318.64225 74243.19 1.0763 0.00071072 173520 114.58 173520 114.58 774.910108702383 109.17 0.47948 109.17 108.86 109.34 -7.6294E-06 14 9 2 0.884378552436829 0.00015749060548842 0.00418261857703328 0.004497 1 52083 89.029 36.45 1 2848200 470.83 746.37 752.98 762.48 815.64 789.39 589.59 696.58 535.45 653.43 444.66 706.4 738.78 781.39 830.68 795.92 606.81 692.69 534.76 649.16 1 1 1 1 1 1 1 1 1 1 23640 18 3178 3334 24438 24438 49 CLIVDFSNPEAPLEIHTAMLALDQFQEK 28 Lys8+TMT6 _CLIVDFSNPEAPLEIHTAMLALDQFQEK(ly)_ CLIVDFSNPEAPLEIHTAMLALDQFQEK(1) CLIVDFSNPEAPLEIHTAMLALDQFQEK(61.14) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 1232.6517 3 1156.26083 3465.76065 NaN NaN NaN NaN NaN NaN NaN NaN 215.54 1 215.54 215.04 216.04 0 NaN NaN NaN 0.0051968 1 109510 61.141 40.107 1 172.88 0 0 0 0 259.54 537.16 0 0 211.78 161.72 0 0 0 0 250.65 515.51 0 0 204.42 1 0 0 0 0 1 1 0 0 1 25356 2 3401 3567 26194 26194 1 CLIVDFSNPEAPLEIHTAMLALDQFQEK 28 Lys8+TMT6 _CLIVDFSNPEAPLEIHTAMLALDQFQEK(ly)_ CLIVDFSNPEAPLEIHTAMLALDQFQEK(1) CLIVDFSNPEAPLEIHTAMLALDQFQEK(48.63) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 1233.3175 3 1156.26083 3465.76065 58220.4 0.58904 0.00068108 66063 76.386 66064 76.387 1233.31687508356 214.34 0.14523 214.34 214.27 214.41 0 4 2 2 0.56591135263443 0.000211117323487997 0.00761774880811572 0.0042009 1 111393 48.634 30.527 1 3566100 0 90.643 94.096 369.69 300.62 214.17 192.33 263.39 304.55 197.58 0 86.856 89.661 362.64 294.87 222.24 201.35 258.59 300.17 197.69 0 1 1 1 1 1 1 1 1 1 25357 2 3401 3567 26195 26195 1 DFALDSEESR 10 Arg10 _DFALDSEESR(ar)_ DFALDSEESR(1) DFALDSEESR(78.34) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_01 M1R1 704.3464 2 589.763609 1177.51267 76118.56 1.2528 0.00073885 194280 114.58 194290 114.58 704.345291449332 103.62 0.66404 103.62 103.28 103.95 0 20 13 2 0.710620999336243 0.000520034343935549 0.0248516499996185 0.010266 1 48063 78.342 41.895 1 5940400 757.83 679.27 1108.8 978.02 908.55 865.71 621.28 644.35 809.07 698.06 715.13 643.99 1090.4 985.83 941.01 875.99 645.18 646.33 800.51 690.85 1 1 1 1 1 1 1 1 1 1 29406 18 3944 4130 30359 30359 33 DFALDSEESR 10 Arg10 _DFALDSEESR(ar)_ DFALDSEESR(1) DFALDSEESR(88.6) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 704.3466 2 589.763609 1177.51267 76281.8 1.3351 0.00078737 194280 114.58 194280 114.58 704.345042026783 102.8 0.519 102.8 102.49 103.01 0 18 10 2 0.32783567905426 0.000188382808119059 0.0091546569019556 0.0034847 1 49912 88.596 71.574 1 11399000 966.51 790.14 943.69 1040.9 1092.4 1139.8 960.5 1329.1 1095.6 744.72 909.42 748.72 950.6 1054.4 1110.8 1150.7 982.53 1302.5 1087.3 754.02 1 1 1 1 1 1 1 1 1 1 29407 18 3944 4130 30360 30360 33 DFALDSEESR 10 Arg10 _DFALDSEESR(ar)_ DFALDSEESR(1) DFALDSEESR(91.7) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 704.3457 2 589.763609 1177.51267 74482.4 1.2218 0.00072059 194280 114.58 194280 114.58 704.344806517013 104.1 0.66164 104.1 103.77 104.44 7.6294E-06 20 13 3 0.595215797424316 0.000295830046525225 0.0171722732484341 0.0025695 1 49368 91.701 69.14 1 6572000 633.25 488.55 575.16 578.33 797.46 659.6 767.22 789.17 705.91 726.98 595.6 462.69 582.97 588.77 804.91 666.2 779.19 777.54 704.71 722.6 1 1 1 1 1 1 1 1 1 1 29408 18 3944 4130 30361 30361 33 DFALDSEESR 10 Arg10 _DFALDSEESR(ar)_ DFALDSEESR(1) DFALDSEESR(115.57) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 704.3465 2 589.763609 1177.51267 76196.02 1.1411 0.00067299 194280 114.58 194290 114.58 704.345469200623 103.44 0.65843 103.44 102.99 103.65 0 23 13 2 0.335747271776199 0.00030646933009848 0.010438316501677 0.00033899 1 49950 115.57 82.486 1 10037000 1048.4 1156.1 1214.9 1249.9 1314.2 1283.5 1555.4 1289.1 1479.7 976.41 987.54 1094.4 1210.6 1277.1 1346.1 1296.1 1568.3 1272.8 1475.7 976.6 1 1 1 1 1 1 1 1 1 1 29409 18 3944 4130 30362 30362 33 DFALDSEESR 10 Arg10 _DFALDSEESR(ar)_ DFALDSEESR(1) DFALDSEESR(108.7) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_03 M3R3 704.3453 2 589.763609 1177.51267 76575.65 0.76203 0.00044941 194280 114.58 194280 114.58 704.344947973175 102.82 0.52002 102.82 102.52 103.04 -7.6294E-06 18 10 2 0.678331971168518 0.000644210667815059 0.0250478647649288 0.00051134 1 50890 108.7 83.844 1 13921000 715.8 583.28 678.22 479.29 871.71 943.22 643.11 778.96 583.52 789.07 673.4 551.59 685.04 500.54 880.37 936.24 661.16 777.38 582.78 782.26 1 1 1 1 1 1 1 1 1 1 29410 18 3944 4130 30363 30363 33 DFALDSEESR 10 Arg10 _DFALDSEESR(ar)_ DFALDSEESR(1) DFALDSEESR(138.25) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_01 M4R1 704.3458 2 589.763609 1177.51267 75198.84 1.0584 0.00062419 194280 114.58 194280 114.58 704.345137921914 103.78 0.61519 103.78 103.48 104.09 0 29 12 3 0.966196894645691 0.000426033686380833 0.0136181935667992 6.1818E-05 1 50305 138.25 91.428 1 7522000 889.42 1133.6 1029.3 1085.1 925.43 890.65 1054.1 962.18 1143.2 954.84 837.78 1072.6 1024.6 1114.4 957.76 908.17 1066.4 951.7 1136 947.12 1 1 1 1 1 1 1 1 1 1 29411 18 3944 4130 30364 30364 33 DFALDSEESR 10 Arg10 _DFALDSEESR(ar)_ DFALDSEESR(1) DFALDSEESR(121.61) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 704.3457 2 589.763609 1177.51267 76655.58 1.1984 0.00070675 194280 114.58 194280 114.58 704.345099389888 102.58 0.56617 102.58 102.3 102.87 -7.6294E-06 20 11 2 0.731366693973541 0.000552579527720809 0.0215593706816435 0.00020963 1 51522 121.61 86.805 1 13595000 1573.2 1327.3 1422 1305.4 1600.3 1358.5 1348.5 1648.5 1413.9 1173.6 1479.6 1256 1439.7 1340.6 1628.9 1375.2 1380.1 1618 1406.3 1176.5 1 1 1 1 1 1 1 1 1 1 29412 18 3944 4130 30365 30365 33 DFALDSEESR 10 Arg10 _DFALDSEESR(ar)_ DFALDSEESR(1) DFALDSEESR(133.89) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_02 M5R2 704.3455 2 589.763609 1177.51267 75179.8 1.1091 0.0006541 194280 114.58 194280 114.58 704.345226414001 102.69 0.7082 102.69 102.37 103.07 0 36 14 3 0.982689499855042 0.000623328378424048 0.0166169926524162 6.6469E-05 1 48473 133.89 100.7 1 4674000 1373.8 1116.2 1178.8 1182.8 1450.1 1179.8 1129.3 1044.6 1270.2 1486.4 1291.7 1056.5 1198.6 1209.5 1468.3 1192.5 1161.6 1047 1261.1 1462.4 1 1 1 1 1 1 1 1 1 1 29413 18 3944 4130 30366 30366 33 DFALDSEESR 10 Arg10 _DFALDSEESR(ar)_ DFALDSEESR(1) DFALDSEESR(128.01) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 704.3459 2 589.763609 1177.51267 74012.04 1.1646 0.00068684 194280 114.58 194280 114.58 704.345085363421 102.42 0.84814 102.42 101.99 102.84 0 38 17 3 0.721016645431519 0.000741521827876568 0.0213779732584953 8.3625E-05 1 48781 128.01 102 1 4023400 1256.8 1050.1 1217.9 1435.4 1228.5 1166.2 1295.3 1172.6 1238 1026.5 1182.5 995.23 1226.3 1449.1 1261.2 1187.9 1311.5 1160 1234.5 1021.8 1 1 1 1 1 1 1 1 1 1 29414 18 3944 4130 30367 30367 33 DGSLFWQSPK 10 Lys8+TMT6 _DGSLFWQSPK(ly)_ DGSLFWQSPK(1) DGSLFWQSPK(63.32) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_02 M5R2 544.3082 3 467.920028 1400.73825 84253.8 0.886 0.00041458 163250 76.387 163250 76.388 544.307338801109 150.88 0.42084 150.88 150.57 150.99 0 14 8 3 0.715318381786346 0.000390146102290601 0.0162515826523304 0.013564 1 75501 63.32 27.643 1 3849100 2635.9 2985.4 2944.2 2495.1 2798.2 2739.7 3158.5 2765 2563.2 2604 2482.3 2823.3 2937.8 2588.2 2885.5 2762.7 3183 2738 2569.2 2586.7 1 1 1 1 1 1 1 1 1 1 31282 2 4203 4399 32293 32293 2 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(45.89) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_01 M1R1 664.7182 3 587.995374 1760.96429 75796 1.1984 0.00070467 129910 76.387 129910 76.388 664.382653680779 223.37 0.7663 223.37 223.01 223.78 0 42 15 4 0.971828281879425 0.00341572100296617 0.0205435641109943 0.056031 1 112129 45.891 10.296 1 8533600 1122.1 1004.7 1169.5 1435.2 1427.7 1039.6 963.45 1273.2 1204.4 1411.3 1056.3 952.51 1173.6 1445.5 1444.3 1068.3 1000.5 1257.6 1192.7 1396 1 1 1 1 1 1 1 1 1 1 46511 2 6240 6537 48036 48036 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(47.06) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_02 M1R2 664.7176 3 587.995374 1760.96429 74837.6 0.76081 0.00044735 129910 76.388 129910 76.388 664.382945107772 222.37 0.97336 222.37 221.96 222.93 1.5259E-05 56 19 4 0.915221095085144 0.00217368523590267 0.052833303809166 0.051467 1 112934 47.062 19.38 1 5840900 1152.2 1143.8 1038.2 999.05 1297.2 1059.5 1288.2 997.99 899.22 1335.3 1083.7 1081.9 1052.1 1033.2 1316 1069.5 1302.2 996.83 906.35 1315.4 1 1 1 1 1 1 1 1 1 1 46512 2 6240 6537 48037 48037 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(74.61) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 664.3844 3 587.995374 1760.96429 74958.77 1.2065 0.0007094 129910 76.387 129910 76.388 664.717143962336 221.65 0.67557 221.65 221.29 221.96 1.5259E-05 41 13 4 0.773600935935974 0.0012862840667367 0.0159777756780386 0.0028845 1 117509 74.611 33.228 1 29961000 2231.5 2058.4 2711.9 2508.9 2472.9 2136.2 2454.5 2250.9 2642.1 2372.4 2102.6 1949.8 2692.7 2545.9 2552.4 2174.7 2495.6 2230.3 2626 2349.5 1 1 1 1 1 1 1 1 1 1 46513 2 6240 6537 48038 48038 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(64.12) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 664.384 3 587.995374 1760.96429 74728.74 1.1408 0.00067077 129910 76.388 129910 76.388 664.717249847526 224.73 0.81421 224.73 224.34 225.16 0 59 16 5 0.966183602809906 0.00190381775610149 0.067793607711792 0.0097694 1 115333 64.121 31.867 1 6503000 1658.5 1362 1459.5 1859.9 1601.1 1342.2 1602.2 1586.8 1331.4 1656.5 1559.6 1290.9 1480.3 1876.6 1635 1378.2 1622.4 1567.1 1333.4 1641 1 1 1 1 1 1 1 1 1 1 46514 2 6240 6537 48039 48039 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(100.02) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 664.3835 3 587.995374 1760.96429 75557.31 1.0995 0.00064648 129910 76.387 129910 76.388 664.716882401721 222.48 0.77577 222.48 222.12 222.89 0 50 15 4 0.865961492061615 0.00144485814962536 0.0170113854110241 0.0002518 2 117993 100.02 63.605 1 16064000 3822.4 3385.9 4026.4 3455.7 3771.4 3308.7 3765.3 4188.2 3850.4 3563.3 3598.3 3204.5 4031.3 3539.8 3886.5 3362.6 3824.3 4115.9 3832.2 3550.4 2 2 2 2 2 2 2 2 2 2 46515 2 6240 6537 48040;48041 48041 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(78.96) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 664.3842 3 587.995374 1760.96429 74427.74 1.6251 0.00095557 129910 76.387 129910 76.388 664.382326735501 221.64 0.66306 221.64 221.34 222.01 -1.5259E-05 43 13 4 0.971156656742096 0.00266480795107782 0.103266641497612 0.0020713 1 112831 78.964 39.086 1 6448600 2129 2094 1969.1 1981.7 2059.9 1824.5 1999.6 2286.2 2294.1 2347.8 2002.7 1981.2 1989.5 2037.9 2108.3 1857.5 2037.1 2253.8 2276.5 2326.7 1 1 1 1 1 1 1 1 1 1 46516 2 6240 6537 48042 48042 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(74.7) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_01 M3R1 664.3837 3 587.995374 1760.96429 76592.51 1.3671 0.00080387 129910 76.387 129910 76.388 664.382761272956 223.38 0.8221 223.38 222.97 223.79 0 48 16 4 0.762390732765198 0.00074108422268182 0.0461813136935234 0.0028682 1 118566 74.698 39.738 1 7557800 1370.1 1282.7 1451.6 1449.2 1305.7 1072 1619.2 1312.1 1307.4 1242.3 1289.8 1214.6 1452.5 1474.7 1352.9 1100 1626.5 1292.6 1310.7 1233.8 1 1 1 1 1 1 1 1 1 1 46517 2 6240 6537 48043 48043 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(45.36) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 664.7189 3 587.995374 1760.96429 74443.5 1.2388 0.0007284 129910 76.387 129910 76.388 664.382804958194 222.67 0.94576 222.67 222.16 223.11 0 62 19 5 0.866641104221344 0.00186293490696698 0.058960072696209 0.058108 1 112638 45.357 17.391 1 5081200 624.55 640.29 606.15 815.02 627.34 635.57 561.92 600.6 585.12 928.55 587.63 606.62 610.4 825.07 641.87 649.06 573.47 601.89 582.06 912.18 1 1 1 1 1 1 1 1 1 1 46518 2 6240 6537 48044 48044 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(71.18) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_03 M3R3 664.3841 3 587.995374 1760.96429 75662.52 1.219 0.00071679 129910 76.387 129910 76.388 664.382796310793 221.88 0.86404 221.88 221.36 222.23 0 55 17 4 0.868302583694458 0.00196158769540489 0.0648070126771927 0.0047021 1 119016 71.176 34.497 1 12033000 1980.2 1712.5 1624.1 1739.5 1940 1703.5 1916.4 1909.9 2166.8 1850.2 1861.5 1620.8 1656.8 1782.5 1972.2 1726.9 1950.5 1886.5 2150.9 1836.5 1 1 1 1 1 1 1 1 1 1 46519 2 6240 6537 48045 48045 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(52.07) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_01 M4R1 664.7184 3 587.995374 1760.96429 75629.3 1.0894 0.00064058 129910 76.388 129910 76.388 664.382821212507 223.11 0.82295 223.11 222.63 223.45 0 49 16 4 0.925859689712524 0.00251907599158585 0.070689432322979 0.033281 1 115669 52.071 24.39 1 9144300 2308.6 2009.3 2075.4 2019.6 1924.5 2483.3 2180.6 2327.2 1970.9 2337.4 2171.2 1901.6 2099.6 2074.1 1987.7 2493.9 2200.3 2312.1 1968.6 2317.8 1 1 1 1 1 1 1 1 1 1 46520 2 6240 6537 48046 48046 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(83.18) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_02 M4R2 664.3835 3 587.995374 1760.96429 74506.51 0.86763 0.00051016 129910 76.388 129910 76.388 664.383052383768 222.45 1.0157 222.45 221.89 222.91 1.5259E-05 67 20 4 0.958913207054138 0.00229342584498227 0.0566942468285561 0.0012833 1 116415 83.182 42.905 1 7857900 1915.1 2090.4 1615.9 1791.1 1982 1977.5 2114.3 1917.7 1771.2 1781.1 1800.5 1977.1 1645.1 1855.1 2014.3 1992.5 2135.9 1900.8 1773.5 1770 1 1 1 1 1 1 1 1 1 1 46521 2 6240 6537 48047 48047 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(60.3) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_03 M4R3 664.7179 3 587.995374 1760.96429 74785.47 1.2512 0.00073569 129910 76.387 129910 76.388 664.716958055966 221.94 0.71843 221.94 221.55 222.27 0 47 14 4 0.972857415676117 0.00689248275011778 0.0968468859791756 0.01547 1 118300 60.301 22.974 1 19141000 2699.8 2553.2 2419.8 2433.5 2932.3 2685.1 2727.9 2905 2189.4 2694.1 2539.1 2415.8 2452.6 2504.5 2976.8 2710 2769.4 2870.2 2195.4 2677.3 1 1 1 1 1 1 1 1 1 1 46522 2 6240 6537 48048 48048 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(46.07) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 664.7184 3 587.995374 1760.96429 76079.16 1.3469 0.00079197 129910 76.387 129910 76.388 664.382711788685 222.35 0.72472 222.35 221.98 222.71 -1.5259E-05 42 14 5 0.789014399051666 0.0017479817615822 0.0229832362383604 0.055335 1 121326 46.069 16.998 1 24945000 3011.3 2704.6 2768.9 2975.8 2883.6 2987.5 2657 2590.5 2924 2935.1 2832.4 2560.6 2798.6 3037.4 2950.3 3015.9 2710.8 2585.9 2904.5 2901.6 1 1 1 1 1 1 1 1 1 1 46523 2 6240 6537 48049 48049 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(56.2) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_02 M5R2 664.717 3 587.995374 1760.96429 74666.88 1.3591 0.00079916 129910 76.387 129910 76.388 664.382811149455 221.93 0.77525 221.93 221.41 222.19 -1.5259E-05 51 15 4 0.861679136753082 0.00174577976576984 0.0657896101474762 0.024335 1 113280 56.205 26.293 1 9226600 1360.5 987.38 1127.7 1301.2 1599.2 1164.8 1254.6 1200.9 1246.7 1129.6 1279 935.62 1150.9 1316.4 1609.1 1182.8 1287.4 1188.4 1241.7 1122.1 1 1 1 1 1 1 1 1 1 1 46524 2 6240 6537 48050 48050 3 EDFTLLDFINAVK 13 Lys8+TMT6 _EDFTLLDFINAVK(ly)_ EDFTLLDFINAVK(1) EDFTLLDFINAVK(80.32) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 664.3837 3 587.995374 1760.96429 75362.27 1.0354 0.00060883 129910 76.388 129910 76.388 664.382802032017 221.53 0.85687 221.53 221.18 222.04 0 53 17 4 0.932015538215637 0.0032753071282059 0.140336483716965 0.0018182 1 114784 80.318 45.358 1 10802000 1818.3 1916 2598.3 2307.5 2266 1911.6 1915.1 2327.6 1600.8 2181.9 1715.5 1814.8 2558.6 2342.4 2341.6 1952.2 1953.5 2292.9 1602.9 2167.6 1 1 1 1 1 1 1 1 1 1 46525 2 6240 6537 48051 48051 3 EIDDEANSYFQR 12 Arg10 _EIDDEANSYFQR(ar)_ EIDDEANSYFQR(1) EIDDEANSYFQR(63.29) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 863.4119 2 748.830012 1495.64547 70627.72 1.0798 0.00080858 153010 114.58 153020 114.58 863.411905994543 122.01 0.51997 122.01 121.83 122.35 -7.6294E-06 19 10 3 0.500435471534729 7.62957861297764E-05 0.00368659943342209 0.035849 1 58827 63.292 42.514 1 4187500 286.34 350.21 300.97 352.27 596.83 276.38 438.91 524.73 334.65 320.24 269.55 331.43 303.18 360.71 592.97 285.18 450.32 509.48 336.17 323 1 1 1 1 1 1 1 1 1 1 52701 18 7078 7416 54522 54522 34 EIDDEANSYFQR 12 Arg10 _EIDDEANSYFQR(ar)_ EIDDEANSYFQR(1) EIDDEANSYFQR(84.73) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_01 M4R1 863.411 2 748.830012 1495.64547 67393.63 1.2308 0.00092168 153010 114.58 153020 114.58 863.41153779797 123.15 0.77537 123.15 122.68 123.46 -7.6294E-06 26 15 2 0.35852387547493 0.000229141020099632 0.0117257684469223 0.003341 1 61405 84.734 53.666 1 3133600 548.6 566.87 286.15 552.42 423.47 632.47 463.02 311.11 200.38 452.3 514.8 536.41 305.26 567.99 426.97 632.55 464.43 320.37 206.86 444.82 1 1 1 1 1 1 1 1 1 1 52702 18 7078 7416 54523 54523 34 EVTAAQVAR 9 Arg10 _EVTAAQVAR(ar)_ EVTAAQVAR(1) EVTAAQVAR(73.84) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 592.3479 2 477.765758 953.516963 81110.55 1.0468 0.00050011 239830 114.58 239830 114.58 592.347280760071 56.83 0.43249 56.83 56.645 57.077 0 17 8 3 0.987252414226532 0.000998296774923801 0.0553996413946152 0.017104 1 23317 73.841 25.882 1 4766700 394.8 382.06 415.57 253.6 614.25 414.45 251.63 428.09 694.81 365.3 371.65 361.07 417.38 268.35 614.12 413.9 276.87 422.99 679.62 363.93 1 1 1 1 1 1 1 1 1 1 64920 18 8829 9241 67190 67190 35 EVTAAQVAR 9 Arg10 _EVTAAQVAR(ar)_ EVTAAQVAR(1) EVTAAQVAR(66.92) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 592.3475 2 477.765758 953.516963 82087.25 1.1225 0.00053629 239830 114.58 239830 114.58 592.34708621005 57.127 0.42884 57.127 56.865 57.293 0 15 8 2 0.771787643432617 0.000863868568558246 0.0478761605918407 0.035836 1 23397 66.92 18.497 1 4591900 512.33 370.41 526.44 487.98 596.05 431.04 383.79 234.72 402.19 413.79 482.21 351 528.48 493.62 605.03 435.32 398.44 241.52 400.02 405.63 1 1 1 1 1 1 1 1 1 1 64921 18 8829 9241 67191 67191 35 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(65.29) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_01 M1R1 853.981 2 738.897366 1475.78018 68482.37 0.42982 0.00031759 155070 114.58 155070 114.58 853.980856972868 125.28 0.5243 125.28 124.99 125.51 7.6294E-06 21 10 3 0.451743602752686 0.000306957168504596 0.00428320234641433 0.039288 1 59965 65.295 25.141 1 9290300 1375.2 1345 1468.2 1648.4 1616.5 1536.1 1481.6 1329.5 1180.8 1302.6 1294.7 1274 1470.2 1673.2 1648.7 1553.9 1504.9 1323.8 1184.3 1292.5 1 1 1 1 1 1 1 1 1 1 65782 278 8957 9375 68075 68075 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(145.31) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_02 M1R2 853.4785 2 738.897366 1475.78018 68389.11 0.84348 0.00062324 155070 114.58 155070 114.58 853.478720636375 124.42 0.37461 124.42 124.22 124.59 0 20 7 4 0.898862302303314 0.000855605583637953 0.0104038044810295 6.7962E-05 1 60400 145.31 73.81 1 19418000 1291.1 1420.6 1324.3 1310.6 1400.6 1146 977.47 1582.5 1161.1 1347.9 1215.2 1344 1329.1 1349.4 1427.9 1170.3 1012.2 1552.1 1151.2 1342.9 1 1 1 1 1 1 1 1 1 1 65783 278 8957 9375 68076 68076 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(80.31) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 853.9814 2 738.897366 1475.78018 68413.8 0.75074 0.00055472 155070 114.58 155070 114.58 853.478674335404 124.22 0.6172 124.22 123.96 124.58 -7.6294E-06 21 12 2 0.763937175273895 0.000346446933690459 0.00278744264505804 0.0082161 1 62555 80.312 46.106 1 19267000 1318.8 1176 1424.8 1601.8 1771.6 1336.7 1599.4 1497.6 1561.4 1428.3 1241.7 1114.5 1426.9 1617.5 1795.7 1362.8 1630.1 1478.8 1556.1 1418.3 1 1 1 1 1 1 1 1 1 1 65784 278 8957 9375 68077 68077 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(80.31) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 853.9822 2 738.897366 1475.78018 68819.34 0.88016 0.00065034 155070 114.58 155070 114.58 853.478737050199 125.62 0.61528 125.62 125.29 125.9 0 30 12 3 0.689403116703033 0.000506238313391805 0.00504458229988813 0.0082161 1 61574 80.312 34.483 1 15753000 2219.4 1895 2122.6 2077.3 2413.5 1840.3 2169.9 2074.9 2231.6 2036.1 2088.1 1794.1 2140.8 2119 2457 1872.4 2213.8 2049.5 2220.7 2020.3 1 1 1 1 1 1 1 1 1 1 65785 278 8957 9375 68078 68078 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(113.99) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 853.4779 2 738.897366 1475.78018 68537.33 1.3113 0.00096891 155070 114.58 155070 114.58 853.478358948813 124.73 0.69476 124.73 124.37 125.07 -7.6294E-06 34 14 3 0.626008689403534 0.000622292456682771 0.00463459175080061 0.00032683 2 62505 113.99 61.506 1 25872000 2711 2481.6 2390.7 2471.9 2521.6 2961.8 2321.3 2622.9 2447.3 2896 2549.4 2348.4 2423.7 2539.4 2578 2975 2366.7 2615.1 2433.7 2864.8 2 2 2 2 2 2 2 2 2 2 65786 278 8957 9375 68079;68080 68079 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(70.54) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 853.9814 2 738.897366 1475.78018 69063.65 0.86228 0.00063714 155070 114.58 155070 114.58 853.479036578082 124.42 0.51274 124.42 124.18 124.69 -7.6294E-06 19 10 3 0.953647613525391 0.000200412585400045 0.00415019132196903 0.023324 1 60087 70.54 22.569 1 13572000 910.77 1125.3 589.37 811.22 941.9 850.47 927.34 1312.1 1266.3 1148.9 855.29 1063.7 615 849.83 945.59 865.35 947.32 1284.5 1251.7 1143.7 1 1 1 1 1 1 1 1 1 1 65787 278 8957 9375 68081 68081 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(131.69) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_01 M3R1 853.48 2 738.897366 1475.78018 69415.67 0.94208 0.0006961 155070 114.58 155070 114.58 853.980500132405 125.32 0.64695 125.32 125.06 125.71 0 26 13 3 0.781232953071594 0.000562900037039071 0.013660934753716 6.9135E-05 1 64302 131.69 81.651 1 16278000 1209.8 1270.2 999.01 1120.3 1258.9 1238.1 1339 1199.5 1205.1 982.86 1137.3 1201.5 1018.9 1158.2 1277.7 1247.1 1354.1 1186.9 1203.9 980.45 1 1 1 1 1 1 1 1 1 1 65788 278 8957 9375 68082 68082 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(166.04) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 853.4797 2 738.897366 1475.78018 68539.11 1.2286 0.00090783 155070 114.58 155070 114.58 853.478813287592 124.32 0.87865 124.32 123.89 124.77 0 45 18 3 0.707873702049255 0.000331878138240427 0.0025222550611943 1.5344E-08 1 59855 166.04 105.6 1 8882300 1174.6 1176.6 1092.9 1128.2 1169.9 967.6 1019.2 1201.8 1192.1 841.59 1104.9 1113.3 1103.9 1158.9 1194.4 986.34 1043.4 1178.6 1182.3 844.15 1 1 1 1 1 1 1 1 1 1 65789 278 8957 9375 68083 68083 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(65.23) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_03 M3R3 853.9806 2 738.897366 1475.78018 67823.4 1.1745 0.00086782 155070 114.58 155070 114.58 853.479010565691 124.28 0.46828 124.28 124.02 124.49 0 23 9 3 0.693360805511475 0.000338053214363754 0.00420880736783147 0.039475 1 63510 65.234 26.429 1 19775000 1319.6 1237.7 1439 1436.1 1523.5 1236.2 1423.6 1458.7 1259.4 1599.8 1242.4 1172.1 1438.8 1460.7 1557.5 1260.5 1446.8 1441.9 1258.8 1582.9 1 1 1 1 1 1 1 1 1 1 65790 278 8957 9375 68084 68084 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(61.34) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_01 M4R1 569.322 3 492.934003 1475.78018 82561.23 0.66398 0.0003273 154970 76.388 154970 76.388 569.321584570404 125.37 0.70403 125.37 124.97 125.67 7.6294E-06 41 14 4 0.780805289745331 0.00170742627233267 0.0202151369303465 0.015073 1 62576 61.344 27.468 1 14303000 2245.4 2059.5 2007.7 2358.8 1998.6 2252.9 1926.8 2459 2028.2 2210.1 2111.8 1950.1 2032.7 2402.1 2051.2 2284.3 1960.6 2427.8 2017 2198.4 1 1 1 1 1 1 1 1 1 1 65791 278 8957 9375 68085 68085 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(131.69) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_02 M4R2 853.4797 2 738.897366 1475.78018 67957.68 1.2026 0.00088856 155070 114.58 155070 114.58 853.478806691766 124.4 0.79762 124.4 124.03 124.82 -7.6294E-06 38 16 3 0.687454044818878 0.000311009847791865 0.00235331710428 6.9135E-05 1 62346 131.69 79.21 1 13917000 1068.6 1032.6 980.7 936.5 1116.9 1302 928.33 1067.9 1019.5 920.8 1005.1 976.83 991.91 968.42 1136 1300.8 951.47 1063.3 1012.7 917.06 1 1 1 1 1 1 1 1 1 1 65792 278 8957 9375 68086 68086 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(156.36) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_03 M4R3 853.4794 2 738.897366 1475.78018 68401.81 0.73484 0.00054297 155070 114.58 155070 114.58 853.479108762969 124.45 0.70047 124.45 124.15 124.85 0 37 14 4 0.665062665939331 0.000310432544210926 0.00228609121404588 6.1463E-06 1 62852 156.36 102.8 1 16368000 1837.7 1677.2 1183.7 1615.8 1337.7 1523.8 1831.1 1626.6 1699 1624 1725.7 1587 1232.5 1660.2 1370.1 1545.6 1837.2 1609.6 1695.7 1610.6 1 1 1 1 1 1 1 1 1 1 65793 278 8957 9375 68087 68087 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(112.02) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 853.4803 2 738.897366 1475.78018 68627.86 1.1913 0.00088028 155070 114.58 155070 114.58 853.478826685547 122.72 0.66116 122.72 122.45 123.11 0 34 13 4 0.954024970531464 0.000376982032321393 0.00311034149490297 0.00037519 1 63533 112.02 72.175 1 35216000 2326.1 2401.8 2555.9 2586.1 2365.7 2028.2 2165.7 2234 2530.2 2513.2 2190.3 2273.7 2552.3 2638.7 2437.2 2073.4 2212.4 2213.3 2509.6 2484.9 1 1 1 1 1 1 1 1 1 1 65794 278 8957 9375 68088 68088 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(86.19) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_02 M5R2 569.3223 3 492.934003 1475.78018 80079.16 0.30999 0.00015281 154970 76.388 154970 76.388 569.321887438381 124.08 0.86337 124.08 123.67 124.53 7.6294E-06 40 17 3 0.761712074279785 0.00228416617028415 0.0110203297808766 0.001053 1 60442 86.189 40.217 1 15093000 1951.6 1752.9 2204.6 2150.1 2684.6 2038.5 2047.1 2293.4 2297.9 2024.9 1838 1660.4 2201.7 2182.6 2719 2068.4 2107.7 2261.7 2281.5 2015.2 1 1 1 1 1 1 1 1 1 1 65795 278 8957 9375 68089 68089 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(97.96) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_02 M5R2 853.9823 2 738.897366 1475.78018 67307.39 0.65398 0.00048322 155070 114.58 155070 114.58 853.980511621734 124.15 0.81496 124.15 123.67 124.48 0 37 16 3 0.977948129177094 0.00044250235077925 0.00353640341199934 0.0012127 1 60446 97.957 37.48 1 9448600 1507.2 1135.9 1291.8 1552.3 1506.7 1474.3 1267.4 1409.3 1264.2 1508.2 1417.2 1076.6 1313.2 1568.6 1530.8 1492.9 1296.3 1400.8 1259.1 1493 1 1 1 1 1 1 1 1 1 1 65796 278 8957 9375 68090 68090 799 EYLLGSTAEEK 11 Lys8+TMT6 _EYLLGSTAEEK(ly)_ EYLLGSTAEEK(1) EYLLGSTAEEK(102.95) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 569.322 3 492.934003 1475.78018 81592.87 0.30043 0.00014809 154970 76.388 154970 76.388 569.321640961766 123.85 0.88642 123.85 123.41 124.3 7.6294E-06 44 18 3 0.922726035118103 0.00176685268525034 0.00668246811255813 0.0002161 1 60878 102.95 24.439 1 17564000 3039.3 2877.1 2371.3 2561.8 2477 2470.3 2679.6 2437.1 2321.1 2421.1 2856.4 2721.6 2426.5 2644.7 2538.8 2500.8 2706.8 2417 2321.5 2401.4 1 1 1 1 1 1 1 1 1 1 65797 278 8957 9375 68091 68091 799 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(97.97) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_01 M1R1 553.3395 3 476.951217 1427.83182 84868.63 0.74515 0.0003554 160160 76.388 160160 76.388 553.338937713596 169.48 0.37425 169.48 169.26 169.64 0 19 7 3 0.810230851173401 0.0011359517229721 0.0464494451880455 0.00039316 1 84861 97.965 25.87 1 8067500 3631.9 3925.5 3585.8 3698 3696.5 3665.3 3741.1 3925.3 3468.4 3868.2 3417.6 3714 3606.8 3805.6 3788.3 3711.7 3792.2 3883.1 3461.7 3837.6 1 1 1 1 1 1 1 1 1 1 71304 278 9654 10095 73788 73788 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(121.68) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 829.5073 2 714.923187 1427.83182 68023.09 1.3836 0.00098914 160270 114.58 160270 114.58 829.504903693238 168.51 0.56459 168.51 168.32 168.89 -1.5259E-05 28 11 4 0.681786060333252 0.000756448600441217 0.0491538792848587 0.00024206 1 88348 121.68 22.111 1 16321000 1528.5 1225.2 1124.3 1376.7 1398.4 1386 1660.5 1753.2 1191.1 1220.2 1436.1 1160.1 1157.4 1403.8 1422.3 1405.5 1668 1718.5 1199.2 1224.2 1 1 1 1 1 1 1 1 1 1 71305 278 9654 10095 73789 73789 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(79.49) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 553.3392 3 476.951217 1427.83182 83001.66 0.74944 0.00035744 160160 76.388 160160 76.388 553.33899632202 169.86 0.52635 169.86 169.67 170.2 -1.5259E-05 16 10 2 0.824520170688629 0.00105776509735733 0.0301867704838514 0.002885 1 86970 79.489 22.34 1 11403000 5176.2 4739.9 5168.1 5048.1 4936.4 5528.2 4961.3 5035.4 5018.2 5282.4 4871.1 4486.8 5192.4 5164.2 5081.3 5568.3 5036.9 5011.1 4996 5232.1 1 1 1 1 1 1 1 1 1 1 71306 278 9654 10095 73790 73790 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(121.5) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 553.339 3 476.951217 1427.83182 83935.68 0.89439 0.00042658 160160 76.388 160160 76.388 553.3388137767 168.92 0.55365 168.92 168.63 169.19 0 27 11 4 0.801933109760284 0.000952978269197047 0.027548311278224 6.6247E-05 1 85296 121.5 61.335 1 11930000 3587.3 3419.1 3071.7 3404.2 3540.7 3221.2 3168.4 2870.4 3087.3 3360 3373 3235.7 3122.5 3491.4 3601.7 3259.8 3230.4 2864.4 3076.9 3319.3 1 1 1 1 1 1 1 1 1 1 71307 278 9654 10095 73791 73791 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(70.4) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_01 M3R1 553.3392 3 476.951217 1427.83182 85218.13 0.441 0.00021034 160160 76.388 160160 76.388 553.339112557389 169.43 0.51071 169.43 169.22 169.73 0 17 10 2 0.886017620563507 0.000855443882755935 0.037138819694519 0.0072802 1 89849 70.399 11.807 1 9874200 4420 4610 5048.4 4594.3 4946.9 5191.4 5154.6 5291.7 5248.1 4794.4 4163 4362.7 5031.8 4717.5 5086.6 5230.8 5226.4 5235.3 5223.9 4767.8 1 1 1 1 1 1 1 1 1 1 71308 278 9654 10095 73792 73792 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(99.79) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 553.339 3 476.951217 1427.83182 83011.56 0.81135 0.00038697 160160 76.388 160160 76.388 553.338923958892 168.93 0.47009 168.93 168.68 169.15 0 22 9 3 0.814842104911804 0.000812537327874452 0.0365380495786667 0.00034711 1 85159 99.788 39.621 1 9111500 4797 4739.3 4903 4777.9 4735.3 4560.2 4708 4356.1 4510.7 4552.7 4514.9 4485.2 4918.9 4897.3 4870.4 4616.5 4777.9 4328.2 4497.6 4509.7 1 1 1 1 1 1 1 1 1 1 71309 278 9654 10095 73793 73793 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(97.97) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_03 M3R3 553.3398 3 476.951217 1427.83182 82953.29 0.66196 0.00031572 160160 76.388 160160 76.388 553.673265959929 168.78 0.65698 168.78 168.42 169.08 0 27 13 3 0.736764669418335 0.000676836643833667 0.0413882210850716 0.00039316 1 89780 97.965 29.34 1 14199000 3693.9 3901.9 4187.3 3705.4 3736.6 3899.2 3772.9 3687.9 3851.8 4003.3 3479 3691.8 4173.2 3813 3863 3934.8 3830.2 3667.8 3833.8 3961.8 1 1 1 1 1 1 1 1 1 1 71310 278 9654 10095 73794 73794 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(97.57) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_03 M4R3 553.3392 3 476.951217 1427.83182 87618.98 0.85711 0.0004088 160160 76.388 160160 76.388 553.33903179928 168.9 0.51617 168.9 168.53 169.05 0 25 10 4 0.97578763961792 0.000533537531737238 0.015842393040657 0.00040328 1 88991 97.565 38.973 1 13262000 2264.1 2134.6 1855.9 1891.3 1941.7 2100.5 2398.6 2100.6 2004.9 1866.8 2128.4 2019.2 1891.7 1954.9 1993.7 2116.8 2410.8 2078.8 2007.6 1857.5 1 1 1 1 1 1 1 1 1 1 71311 278 9654 10095 73795 73795 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(103.88) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 553.3391 3 476.951217 1427.83182 82574.06 0.52565 0.00025071 160160 76.388 160160 76.388 553.339031494692 168.18 0.42711 168.18 167.91 168.34 0 18 8 3 0.838379681110382 0.000960208242759109 0.0477002039551735 0.00024375 1 90678 103.88 50.281 1 25887000 2848.7 2127 2609.7 2576.2 2585 2707.1 2787.8 2504.1 2721.2 2538.1 2679.5 2014.6 2637.6 2618.5 2657.5 2730.5 2821.2 2489.3 2711.9 2516.2 1 1 1 1 1 1 1 1 1 1 71312 278 9654 10095 73796 73796 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(71.18) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_02 M5R2 829.5059 2 714.923187 1427.83182 69223.96 1.278 0.00091368 160270 114.58 160270 114.58 829.505144146632 168.85 0.51727 168.85 168.52 169.04 0 17 10 2 0.347623378038406 0.000670759472995996 0.0507163107395172 0.024484 1 85826 71.176 24.824 1 10830000 1065.4 1351.3 1112.1 1125.3 888.18 559.93 987.55 754.02 1091.1 941.18 1002.9 1277.9 1113.2 1163.1 926.34 588.28 1000.2 744.85 1083.8 928.43 1 1 1 1 1 1 1 1 1 1 71313 278 9654 10095 73797 73797 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(77.19) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_02 M5R2 553.3398 3 476.951217 1427.83182 84311.95 0.60799 0.00028998 160160 76.388 160160 76.388 553.33903608717 168.84 0.56107 168.84 168.57 169.13 0 24 11 4 0.773752272129059 0.000991484033875167 0.0475251823663712 0.0035406 1 85853 77.192 17.025 1 10144000 3086.9 2464.1 2888.9 2850.2 2960.2 2717.2 2865.7 2653.8 2851.3 2851.7 2903.8 2333.4 2916.1 2901.3 3033.2 2751.9 2912.9 2636.3 2840 2822.8 1 1 1 1 1 1 1 1 1 1 71314 278 9654 10095 73798 73798 800 FIVDLTVQEK 10 Lys8+TMT6 _FIVDLTVQEK(ly)_ FIVDLTVQEK(1) FIVDLTVQEK(104.42) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 553.3395 3 476.951217 1427.83182 83733.45 0.89463 0.0004267 160160 76.388 160160 76.388 553.338839496869 168.79 0.46808 168.79 168.54 169.01 0 20 9 3 0.819934606552124 0.00116335065104067 0.0635823905467987 0.00022997 1 86715 104.42 54.383 1 12671000 3803.5 3534.2 4525.6 3647.8 3955.3 3912.5 3754.6 3776.1 3694.3 4249.6 3583.4 3345.1 4497.6 3737.2 4091.7 3947.5 3819 3755.7 3680.8 4201.9 1 1 1 1 1 1 1 1 1 1 71315 278 9654 10095 73799 73799 800 FWQTYSSAEEVLQK 14 Lys8+TMT6 _FWQTYSSAEEVLQK(ly)_ FWQTYSSAEEVLQK(1) FWQTYSSAEEVLQK(59.29) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_02 M1R2 728.0623 3 651.673071 1951.99738 70902.23 1.4136 0.00092123 117220 76.388 117220 76.389 728.061804109264 174.81 1.0791 174.81 174.12 175.2 0 38 22 3 0.604667782783508 0.00162158068269491 0.0753671005368233 0.015459 1 89029 59.294 7.3553 1 14162000 769.94 858.65 672.23 662.89 791.15 835.69 1095.6 919.6 970.25 612.11 724.02 811.84 682.48 692 808.79 839.88 1098.1 904.19 969.75 615.17 1 1 1 1 1 1 1 1 1 1 77445 2 10476 10956 80094 80094 4 FWQTYSSAEEVLQK 14 Lys8+TMT6 _FWQTYSSAEEVLQK(ly)_ FWQTYSSAEEVLQK(1) FWQTYSSAEEVLQK(64.37) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_01 M3R1 728.3954 3 651.673071 1951.99738 72092.11 1.4771 0.00096256 117220 76.388 117220 76.389 728.394754013058 175.6 1.0439 175.6 174.76 175.81 0 31 21 2 0.531363904476166 0.000622026564087719 0.00711617060005665 0.007816 2 93358 64.374 36.023 1 12920000 1323.6 1190.3 1018.7 1602.3 977.98 1560.5 1255.6 1360.5 1414.2 1324.7 1243.9 1128.1 1043.1 1620.4 1009.8 1576.4 1266.1 1354.3 1404 1314.7 2 2 2 2 2 2 2 2 2 2 77446 2 10476 10956 80095;80096 80096 4 FWQTYSSAEEVLQK 14 Lys8+TMT6 _FWQTYSSAEEVLQK(ly)_ FWQTYSSAEEVLQK(1) FWQTYSSAEEVLQK(62.29) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 728.3956 3 651.673071 1951.99738 70286.86 1.3663 0.00089037 117220 76.388 117220 76.389 728.061504116229 174.87 1.1784 174.87 174.38 175.56 0 36 24 2 0.40269672870636 0.000543060363270342 0.0122886709868908 0.0091453 1 88633 62.287 22.34 1 7780200 591.84 785.53 774.84 906.56 798.39 797.59 1046 1108.8 852.66 1049.3 557.99 743.86 766.92 922.43 821.21 814.75 1049.1 1089 854.53 1042.2 1 1 1 1 1 1 1 1 1 1 77447 2 10476 10956 80097 80097 4 GLHNVVYGIQR 11 Arg10 _GLHNVVYGIQR(ar)_ GLHNVVYGIQR(1) GLHNVVYGIQR(41.16) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 498.9588 3 422.571134 1264.69157 89138.66 0.50778 0.00021458 180770 76.388 180770 76.388 498.958620828736 82.225 0.28023 82.225 82.063 82.343 0 16 4 5 0.76796543598175 0.00117793574463576 0.0210950914770365 0.057123 1 37894 41.164 18.835 1 46728000 487.55 503.1 366.15 342.43 646.17 655.52 600.56 455.98 576.15 346.2 458.14 475.49 377.36 362.29 645.97 649.34 611.18 456.24 574.46 346.24 1 1 1 1 1 1 1 1 1 1 87846 18 11820 12368 90851 90851 HEFSVDMTCGGCAEAVSR 18 Arg10 _HEFSVDMTCGGCAEAVSR(ar)_ HEFSVDMTCGGCAEAVSR(1) HEFSVDMTCGGCAEAVSR(123.08) 1 0 0 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_02 M1R2 751.3378 3 674.949576 2021.8269 76236.84 0.97192 0.000656 113180 76.388 113180 76.388 751.337100394715 101.77 0.61697 101.77 101.58 102.2 7.6294E-06 15 12 2 0.911125838756561 0.000517054810188711 0.0306401867419481 9.2908E-08 1 47797 123.08 110.3 1 4917000 224.48 406.38 285.17 358.12 403.14 514.27 439.01 286.87 353.89 216.81 211.59 384.4 283.31 371.08 407.21 511.32 442.95 290.06 354.8 216.87 1 1 1 1 1 1 1 1 1 1 97638 104 13132 13748 100966 100966 239 HEFSVDMTCGGCAEAVSR 18 Arg10 _HEFSVDMTCGGCAEAVSR(ar)_ HEFSVDMTCGGCAEAVSR(1) HEFSVDMTCGGCAEAVSR(86.41) 1 0 0 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 751.6728 3 674.949576 2021.8269 73017.02 1.1242 0.00075877 113170 76.387 113180 76.388 751.671819011339 101.4 0.2798 101.4 101.18 101.46 0 10 5 3 0.835463523864746 0.00076484412420541 0.0181269329041243 0.00012869 1 49166 86.411 74.768 1 17948000 362.71 526.74 258.89 375.24 367.61 566.49 446.31 416.55 446.28 324.52 340.75 497.9 267.47 394.62 371.83 564.1 449.97 415.96 444.45 324.27 1 1 1 1 1 1 1 1 1 1 97639 104 13132 13748 100967 100967 239 HEFSVDMTCGGCAEAVSR 18 Arg10 _HEFSVDMTCGGCAEAVSR(ar)_ HEFSVDMTCGGCAEAVSR(1) HEFSVDMTCGGCAEAVSR(108.96) 1 0 0 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 751.675 3 674.949576 2021.8269 77210.04 0.89564 0.00060451 113180 76.388 113180 76.389 751.672400338674 102.84 0.52418 102.84 102.54 103.06 -7.6294E-06 10 10 2 0 0 0 8.2977E-07 1 48652 108.96 100.58 1 5794100 560.11 470.08 489.43 469.31 556.77 538.9 513.08 446.54 509.67 667.94 526.7 444.86 496.75 481.91 566.94 541.97 522.61 449.12 507.66 656.55 1 1 1 1 1 1 1 1 1 1 97640 104 13132 13748 100968 100968 239 HEFSVDMTCGGCAEAVSR 18 Arg10 _HEFSVDMTCGGCAEAVSR(ar)_ HEFSVDMTCGGCAEAVSR(1) HEFSVDMTCGGCAEAVSR(54.41) 1 0 0 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_03 M4R3 751.6722 3 674.949576 2021.8269 74833.59 0.85689 0.00057835 113170 76.387 113180 76.388 751.337115133018 101.65 0.68902 101.65 101.25 101.94 0 23 14 3 0.733416318893433 0.000109348184196278 0.00198613828979433 0.014966 1 49762 54.412 42.681 1 6470000 1212 1318.4 1328.1 1344.7 1290 1345.8 1249 1395.4 1208.2 933.28 1141.2 1247.8 1326.8 1377.8 1325.9 1360.4 1269.1 1374.4 1204.4 937.78 1 1 1 1 1 1 1 1 1 1 97641 104 13132 13748 100969 100969 239 IDAHLNK 7 Lys8+TMT6 _IDAHLNK(ly)_ IDAHLNK(1) IDAHLNK(91.63) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_03 M3R3 426.2672 3 349.879504 1046.61668 92496.63 0.25743 9.0068E-05 218330 76.388 218330 76.388 426.267177564732 48.577 0.96743 48.577 48.171 49.138 3.8147E-06 69 20 5 0.989778161048889 0.0381337776780128 0.907759666442871 0.0031754 1 19737 91.626 9.3213 1 304990000 7753.2 7546.1 7541.9 7371.5 7946.3 6861.4 7089.1 7224.1 6781 6427.4 7295 7140.7 7594.5 7567.5 8121.9 6959.1 7226.9 7138.5 6761.7 6395.2 1 1 1 1 1 1 1 1 1 1 103736 2 13938 14599 107391 107391 5 IDAHLNK 7 Lys8+TMT6 _IDAHLNK(ly)_ IDAHLNK(1) IDAHLNK(60.97) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_01 M4R1 426.267 3 349.879504 1046.61668 93069.53 -0.088949 -3.1121E-05 218330 76.388 218330 76.388 426.267291363624 49.545 1.0468 49.545 49.103 50.149 0 68 21 5 0.971924901008606 0.0117422733455896 0.178554624319077 0.027877 1 19947 60.972 6.767 1 198820000 9805.3 9485.3 8752.1 9805.2 8587.9 7892.8 9161.4 8819.2 8492.5 8276 9221.4 8977.7 8861.6 10027 8832.3 8057.3 9267.9 8707.2 8476.2 8221.8 1 1 1 1 1 1 1 1 1 1 103737 2 13938 14599 107392 107392 5 IIPAIATTTATVSGLVALEMIK 22 Lys8+TMT6 _IIPAIATTTATVSGLVALEMIK(ly)_ IIPAIATTTATVSGLVALEMIK(1) IIPAIATTTATVSGLVALEMIK(60.62) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_02 M1R2 893.8801 3 817.491401 2449.45237 NaN NaN NaN NaN NaN NaN NaN NaN 242.49 1 242.49 241.99 242.99 -1.5259E-05 NaN NaN NaN 0.029739 1 121895 60.621 17.914 1 0 0 0 0 0 0 78.284 0 0 0 0 0 0 0 0 0 78.284 0 0 0 0 0 0 0 0 0 1 0 0 0 108946 2 14640 15337 112773 112773 6 IIPAIATTTATVSGLVALEMIK 22 Lys8+TMT6 _IIPAIATTTATVSGLVALEMIK(ly)_ IIPAIATTTATVSGLVALEMIK(1) IIPAIATTTATVSGLVALEMIK(56.72) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 893.8798 3 817.491401 2449.45237 NaN NaN NaN NaN NaN NaN NaN NaN 242.89 1 242.89 242.39 243.39 -1.5259E-05 NaN NaN NaN 0.041081 1 127325 56.719 17.202 1 0 221 0 0 0 64.17 0 0 0 0 0 208.3 0 0 0 61.821 0 0 0 0 0 1 0 0 0 1 0 0 0 0 108947 2 14640 15337 112774 112774 6 IIPAIATTTATVSGLVALEMIK 22 Lys8+TMT6 _IIPAIATTTATVSGLVALEMIK(ly)_ IIPAIATTTATVSGLVALEMIK(1) IIPAIATTTATVSGLVALEMIK(56.02) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 893.879 3 817.491401 2449.45237 NaN NaN NaN NaN NaN NaN NaN NaN 241.49 1 241.49 240.99 241.99 0 NaN NaN NaN 0.04383 1 121733 56.017 17.022 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108948 2 14640 15337 112775 112775 6 IIPAIATTTATVSGLVALEMIK 22 Lys8+TMT6 _IIPAIATTTATVSGLVALEMIK(ly)_ IIPAIATTTATVSGLVALEMIK(1) IIPAIATTTATVSGLVALEMIK(107.91) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 893.8782 3 817.491401 2449.45237 NaN NaN NaN NaN NaN NaN NaN NaN 242.1 1 242.1 241.6 242.6 0 NaN NaN NaN 4.9679E-07 1 130953 107.91 63.654 1 203.04 326.11 0 98.572 352.15 204.93 215.51 179.76 179.46 281.99 189.94 307.74 0 114.48 338.71 203.68 223.72 180.65 179.73 276.94 1 1 0 1 1 1 1 1 1 1 108949 2 14640 15337 112776 112776 6 KPNVGCQQDSEELLK 15 2 Lys8+TMT6 _K(ly)PNVGCQQDSEELLK(ly)_ K(1)PNVGCQQDSEELLK(1) K(88.31)PNVGCQQDSEELLK(88.31) 0 0 2 0 1 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 816.7964 3 740.407413 2218.20041 68986.86 1.4697 0.0010882 103170 76.388 103170 76.389 816.795182283203 107.12 0.32101 107.12 106.93 107.25 0 16 6 3 0.98073422908783 0.000352775328792632 0.00584120070561767 0.0014897 1 52503 88.311 48.401 1 29347000 1773.1 1735.1 1752.1 1773.6 1819.7 1933.2 1620.8 1890.3 1976.5 1973.9 1668.5 1642.2 1762.3 1818.2 1861.4 1949.4 1659 1876.8 1958.5 1955.4 1 1 1 1 1 1 1 1 1 1 120553 2 16403 17181 124698 124698 7;8 KPNVGCQQDSEELLK 15 2 Lys8+TMT6 _K(ly)PNVGCQQDSEELLK(ly)_ K(1)PNVGCQQDSEELLK(1) K(106.6)PNVGCQQDSEELLK(106.6) 0 0 2 0 1 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 816.796 3 740.407413 2218.20041 68812.74 1.5744 0.0011657 103170 76.387 103170 76.388 816.794899185966 108.1 0.42596 108.1 107.85 108.28 0 20 8 3 0.807819366455078 0.000793855113442987 0.0293470527976751 0.00019247 1 51658 106.6 67.57 1 12852000 1479.8 1762.7 1427.7 1814.4 1738.4 1775.7 1768.2 1844.9 2089.1 1756 1392.3 1668.4 1439.8 1858 1766.2 1797.9 1798.9 1825.6 2071.6 1743.8 1 1 1 1 1 1 1 1 1 1 120554 2 16403 17181 124699 124699 7;8 KPNVGCQQDSEELLK 15 2 Lys8+TMT6 _K(ly)PNVGCQQDSEELLK(ly)_ K(1)PNVGCQQDSEELLK(1) K(88.56)PNVGCQQDSEELLK(88.56) 0 0 2 0 1 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 816.7953 3 740.407413 2218.20041 NaN NaN NaN NaN NaN NaN NaN NaN 106.58 1 106.58 106.08 107.08 -7.6294E-06 NaN NaN NaN 0.0018229 1 51141 88.561 50.948 1 1033.2 780.63 716.9 867.23 1065.2 832.63 1025.4 1051.1 854.31 891.25 970.49 739.09 742.79 884.5 1072.1 846.05 1040 1032.9 855.56 888.1 1 1 1 1 1 1 1 1 1 1 120555 2 16403 17181 124700 124700 7;8 LFCDFGDEFEVLDTTGEEPK 20 Lys8+TMT6 _LFCDFGDEFEVLDTTGEEPK(ly)_ LFCDFGDEFEVLDTTGEEPK(1) LFCDFGDEFEVLDTTGEEPK(107.63) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_01 M1R1 939.129 3 862.40639 2584.19734 63896.54 0.87887 0.00075794 88575 76.388 88576 76.388 939.128132642335 207.11 0.76413 207.11 206.82 207.58 1.5259E-05 54 15 5 0.8293137550354 0.0032060113735497 0.0739880427718163 9.4995E-08 1 104588 107.63 82.835 1 6800700 275.11 550.91 478.71 291.36 532.47 420.62 537.48 495.92 340.86 342.7 260.03 520.36 468.2 314.16 543.42 421.85 542.44 486.92 344.93 343.91 1 1 1 1 1 1 1 1 1 1 128078 2 17506 18322 132456 132456 9 LFCDFGDEFEVLDTTGEEPK 20 Lys8+TMT6 _LFCDFGDEFEVLDTTGEEPK(ly)_ LFCDFGDEFEVLDTTGEEPK(1) LFCDFGDEFEVLDTTGEEPK(87.24) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_02 M1R2 939.1281 3 862.40639 2584.19734 61687.96 0.77187 0.00066566 88575 76.388 88576 76.388 939.128331306134 205.82 0.62817 205.82 205.54 206.17 0 43 12 5 0.890071570873261 0.00281709572300315 0.0691863596439362 6.5383E-05 2 105269 87.24 60.828 1 10072000 1581.4 1312.1 977.22 1156.2 1821.7 1452.2 1290.2 1360.9 1516.6 1371.2 1484.8 1241.1 1025.8 1196.7 1812.8 1457.6 1334.7 1352.1 1504.1 1359.5 2 2 2 2 2 2 2 2 2 2 128079 2 17506 18322 132457;132458 132457 9 LFCDFGDEFEVLDTTGEEPK 20 Lys8+TMT6 _LFCDFGDEFEVLDTTGEEPK(ly)_ LFCDFGDEFEVLDTTGEEPK(1) LFCDFGDEFEVLDTTGEEPK(93.23) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 938.796 3 862.40639 2584.19734 63196.73 1.1456 0.00098796 88575 76.387 88576 76.388 939.128115409362 205.27 0.42303 205.27 205.09 205.51 1.5259E-05 33 8 5 0.755300939083099 0.00119371677283198 0.0475739501416683 2.1374E-05 2 109199 93.226 73.971 1 25626000 785.23 1269.3 1122.6 1326.1 1095.9 896.28 1162 761.37 1141.1 1094.8 740.84 1201.5 1106.1 1354.2 1127.3 919.43 1176.7 764.36 1137 1076.9 2 2 2 2 2 2 2 2 2 2 128080 2 17506 18322 132459;132460 132460 9 LFCDFGDEFEVLDTTGEEPK 20 Lys8+TMT6 _LFCDFGDEFEVLDTTGEEPK(ly)_ LFCDFGDEFEVLDTTGEEPK(1) LFCDFGDEFEVLDTTGEEPK(105.02) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 939.129 3 862.40639 2584.19734 62576.44 1.023 0.00088221 88575 76.387 88576 76.388 939.128196592434 205.77 0.90997 205.77 205.57 206.48 -1.5259E-05 58 18 5 0.90967458486557 0.0040580234490335 0.0782211646437645 7.4799E-07 2 109665 105.02 70.151 1 11035000 1160 1025.3 1154 1062.6 1195.7 1343 983.89 1177.3 1025.4 1140.7 1091.6 970.45 1160.2 1089.7 1222.3 1346.4 1008 1171.6 1020 1132.2 2 2 2 2 2 2 2 2 2 2 128081 2 17506 18322 132461;132462 132462 9 LFCDFGDEFEVLDTTGEEPK 20 Lys8+TMT6 _LFCDFGDEFEVLDTTGEEPK(ly)_ LFCDFGDEFEVLDTTGEEPK(1) LFCDFGDEFEVLDTTGEEPK(107.15) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_03 M3R3 939.1295 3 862.40639 2584.19734 62883.02 1.0588 0.00091313 88575 76.388 88576 76.389 939.128242958549 205.09 0.70673 205.09 204.89 205.6 0 55 14 5 0.907847762107849 0.00271875690668821 0.0176024362444878 9.9497E-08 1 110504 107.15 82.361 1 15546000 1059.5 1064 1078.2 1194.5 1355.4 904.5 977.8 1169.4 889.51 939.06 997.18 1007.4 1083.8 1216 1370 927.6 1006.5 1147.7 888.31 937.38 1 1 1 1 1 1 1 1 1 1 128082 2 17506 18322 132463 132463 9 LFCDFGDEFEVLDTTGEEPK 20 Lys8+TMT6 _LFCDFGDEFEVLDTTGEEPK(ly)_ LFCDFGDEFEVLDTTGEEPK(1) LFCDFGDEFEVLDTTGEEPK(91.52) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_01 M4R1 939.1282 3 862.40639 2584.19734 62532.68 0.98067 0.00084573 88575 76.387 88576 76.388 939.128034658029 206.31 0.52905 206.31 206.09 206.62 0 38 10 6 0.763185262680054 0.000743298383895308 0.0381261631846428 3.3927E-05 1 107613 91.518 58.66 1 14682000 416.17 481.71 248.95 511.84 936.39 611.35 446.57 480.75 561.25 593.27 390.7 455.99 264.89 524.01 913.97 613.36 474.79 482.38 555.75 585.38 1 1 1 1 1 1 1 1 1 1 128083 2 17506 18322 132464 132464 9 LFCDFGDEFEVLDTTGEEPK 20 Lys8+TMT6 _LFCDFGDEFEVLDTTGEEPK(ly)_ LFCDFGDEFEVLDTTGEEPK(1) LFCDFGDEFEVLDTTGEEPK(65.02) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_02 M4R2 939.1288 3 862.40639 2584.19734 63879.5 1.2037 0.0010381 88574 76.387 88576 76.388 939.127883213282 205.8 0.71349 205.8 205.39 206.1 -1.5259E-05 48 14 5 0.798769116401672 0.00284221512265503 0.0666891634464264 0.0024583 1 108289 65.022 35.93 1 10785000 771.63 825.29 804.21 836.45 801.36 790.18 873.73 683.48 994.88 849.13 726.33 781.06 805.99 857.05 823.66 799.51 886.04 683.55 987.42 837.71 1 1 1 1 1 1 1 1 1 1 128084 2 17506 18322 132465 132465 9 LFCDFGDEFEVLDTTGEEPK 20 Lys8+TMT6 _LFCDFGDEFEVLDTTGEEPK(ly)_ LFCDFGDEFEVLDTTGEEPK(1) LFCDFGDEFEVLDTTGEEPK(106.31) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 939.129 3 862.40639 2584.19734 64092.44 1.0762 0.00092811 88575 76.387 88576 76.388 939.127910254655 205.36 0.67818 205.36 205.07 205.75 0 48 13 5 0.871810674667358 0.00381936994381249 0.0772248134016991 1.933E-07 1 106866 106.31 75.366 1 15080000 818.62 738.29 856.49 774.33 756.05 571.68 1067.6 932.48 738.76 828.83 770.59 698.83 857.63 790.89 785.97 589.98 1066.3 912.03 744.87 824.71 1 1 1 1 1 1 1 1 1 1 128085 2 17506 18322 132466 132466 9 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(87.43) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_01 M1R1 809.4294 3 733.042835 2196.10667 68527.16 1.2098 0.00088684 104210 76.387 104210 76.388 809.764999762838 197.55 0.52548 197.55 197.17 197.7 1.5259E-05 32 10 5 0.947236776351929 0.00122326740529388 0.0212587062269449 0.00014759 1 99901 87.429 57.849 1 13998000 921.34 913.06 1021.7 961.69 888.01 919.17 907.05 1082.3 743.43 790.19 867.6 864.27 1019.4 983.45 919.76 932.6 917.59 1063.4 744.93 791.38 1 1 1 1 1 1 1 1 1 1 134080 219 18343 19194 138646 138646 630 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(89.88) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_02 M1R2 809.4318 3 733.042835 2196.10667 68271.26 1.504 0.0011025 104210 76.387 104210 76.389 809.764330104543 196.47 0.47858 196.47 196.16 196.63 0 31 9 4 0.757036328315735 0.000971750007010996 0.0401388555765152 0.00011241 1 100694 89.877 47.563 1 10185000 714.06 736.45 569.34 638.57 877.01 753.24 687.7 682.45 801.8 642.01 671.17 696.57 583.2 661.23 879.47 756.82 707.54 678.06 795.32 637.76 1 1 1 1 1 1 1 1 1 1 134081 219 18343 19194 138647 138647 630 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(91.14) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 809.7657 3 733.042835 2196.10667 67830.36 1.3662 0.0010015 104210 76.387 104210 76.388 809.43003481547 195.99 0.32422 195.99 195.8 196.13 0 17 6 4 0.823632955551147 0.0025735532399267 0.0325512290000916 9.4257E-05 1 104013 91.14 52.332 1 37680000 784.54 859.54 760.75 635.74 759.1 591.68 459.95 561.13 691.34 797.23 738.17 812.57 765.96 664.25 775.58 600.04 482.54 561.12 682.06 784.37 1 1 1 1 1 1 1 1 1 1 134082 219 18343 19194 138648 138648 630 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(89.5) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 809.4313 3 733.042835 2196.10667 68444.72 1.3424 0.00098406 104210 76.387 104210 76.388 809.764290440084 196.42 0.49776 196.42 196.15 196.65 0 26 10 4 0.773481905460358 0.00168131233658642 0.0176316872239113 0.0001178 1 104469 89.502 41.285 1 21392000 531.17 442.53 544.76 412.5 401.76 567.02 545.34 688.44 751.2 551.98 499.94 418.67 545.71 425.83 422.75 569.83 551.09 676.69 742.38 551.02 1 1 1 1 1 1 1 1 1 1 134083 219 18343 19194 138649 138649 630 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(75.38) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_01 M3R1 809.4307 3 733.042835 2196.10667 69257.63 1.2559 0.00092062 104210 76.388 104210 76.388 809.43047277422 197.09 0.5238 197.09 196.66 197.18 -1.5259E-05 35 10 5 0.867629945278168 0.00104770937468857 0.0327080301940441 0.00093387 1 105414 75.376 39.347 1 13764000 881.17 1079.3 890.03 1261.8 1166.6 1054.3 1166.9 961.36 811.89 1099.2 829.28 1022.1 895.36 1282.7 1181 1072 1179.2 958.18 818.43 1086.4 1 1 1 1 1 1 1 1 1 1 134084 219 18343 19194 138650 138650 630 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(74.15) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_03 M3R3 809.7664 3 733.042835 2196.10667 68653.89 1.2383 0.0009077 104210 76.388 104210 76.388 809.430438816423 195.88 0.79758 195.88 195.59 196.39 0 56 16 4 0.697124183177948 0.00129866146016866 0.0185509193688631 0.0010348 1 105366 74.147 40.882 1 12125000 998.39 821.22 693.67 535.56 811.81 726.19 916.34 942.96 832.44 663.57 937.84 776.07 717.38 566.52 827.55 730.66 924.84 923.84 831.35 665.47 1 1 1 1 1 1 1 1 1 1 134085 219 18343 19194 138651 138651 630 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(83.75) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_01 M4R1 809.7643 3 733.042835 2196.10667 69639.09 1.2133 0.0008894 104210 76.387 104210 76.388 809.764414675481 196.51 0.71661 196.51 196.2 196.92 -1.5259E-05 38 14 4 0.778482913970947 0.00121443916577846 0.0120963528752327 0.00024645 1 102470 83.751 57.459 1 5879900 782.2 835.21 375.9 643.15 762.36 544.91 597.32 658.43 803.42 744.65 733.82 789.67 406.16 669.72 757.38 556.27 616.24 650.83 794.38 736.2 1 1 1 1 1 1 1 1 1 1 134086 219 18343 19194 138652 138652 630 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(65.1) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_02 M4R2 809.431 3 733.042835 2196.10667 69793.06 1.3783 0.0010104 104210 76.387 104210 76.388 809.764422370067 195.99 0.81554 195.99 195.75 196.56 0 38 16 3 0.197265446186066 0.00016406926442869 0.00495082652196288 0.0041711 1 103224 65.105 26.844 1 8266100 680.35 928.43 764.22 767.23 976.87 624.19 980.35 783.65 775.24 755.47 640.72 878 763.73 794.98 990.07 638.28 991.99 771.73 777.76 749.96 1 1 1 1 1 1 1 1 1 1 134087 219 18343 19194 138653 138653 630 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(77.22) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 809.7659 3 733.042835 2196.10667 68755.17 1.104 0.0008093 104210 76.387 104210 76.388 809.764889967755 195.89 0.56976 195.89 195.62 196.19 0 33 12 6 0.896910548210144 0.00161722977645695 0.0220716651529074 0.00078242 1 106868 77.221 44.074 1 40544000 746.74 547.37 427.53 278.88 636.09 539.52 858.39 733.32 782.71 565.61 700.94 516.97 451.41 302.74 643.23 539.55 861.41 718.51 781.6 565.36 1 1 1 1 1 1 1 1 1 1 134088 219 18343 19194 138654 138654 630 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(65.1) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_02 M5R2 809.765 3 733.042835 2196.10667 67551.56 1.1582 0.00084903 104210 76.388 104210 76.388 809.430736506412 196.54 0.41487 196.54 196.26 196.68 1.5259E-05 17 8 3 0.879623234272003 0.00158894748892635 0.0171717926859856 0.0041711 1 100959 65.105 36.477 1 21324000 838.76 599.75 945.95 683.16 918.49 692.25 826.18 871.51 847.52 777.66 789.93 567.9 943.46 696.17 943.31 702.25 842.81 857.17 843.44 773.7 1 1 1 1 1 1 1 1 1 1 134089 219 18343 19194 138655 138655 630 LLAEMDSQFDSTTGFLGK 18 Lys8+TMT6 _LLAEMDSQFDSTTGFLGK(ly)_ LLAEMDSQFDSTTGFLGK(1) LLAEMDSQFDSTTGFLGK(78.44) 0 0 1 0 0 O15155 O15155 O15155 BET1 BET1 homolog MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 809.766 3 733.042835 2196.10667 68926.27 1.5415 0.00113 104210 76.388 104210 76.389 809.764137958152 196.2 0.42334 196.2 195.87 196.29 1.5259E-05 25 8 4 0.895050406455994 0.00179329060483724 0.037970095872879 0.00068227 1 101996 78.441 39.552 1 27736000 726.97 659.57 988.81 611.66 803.24 776.43 686.86 806.34 706.66 812.69 685.6 624.01 975.65 631.19 834.16 780.3 702.31 798.66 703.2 805.79 1 1 1 1 1 1 1 1 1 1 134090 219 18343 19194 138656 138656 630 MLYVPVMPGHAK 12 Lys8+TMT6 _MLYVPVMPGHAK(ly)_ MLYVPVMPGHAK(1) MLYVPVMPGHAK(57.17) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 603.6854 3 527.297565 1578.87087 79105.35 1.2446 0.00065629 144870 76.388 144870 76.388 603.685053628731 139.31 0.19217 139.31 139.2 139.39 0 8 3 3 0.220529913902283 0.000520595349371433 0.0102211013436317 0.022912 1 68291 57.174 17.158 1 21095000 883.34 1067.4 1162.1 920.22 943.59 1052.9 960.35 862.28 1072.5 905.91 832.84 1009.6 1148.5 952.99 981.86 1057.7 976.06 861.32 1065 897.26 1 1 1 1 1 1 1 1 1 1 153656 2 21100 22094 158828 158828 10 MYYFGIAALDR 11 Arg10 _MYYFGIAALDR(ar)_ MYYFGIAALDR(1) MYYFGIAALDR(78.34) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 779.913 2 665.330408 1328.64626 71642.21 1.5542 0.0010341 172220 114.58 172220 114.58 779.911558186098 177.1 0.68288 177.1 176.91 177.59 0 24 13 3 0.708828568458557 0.00079907919280231 0.0481321774423122 0.0086437 1 91094 78.342 13.117 1 5721600 299.92 422.63 501.53 332.25 264.79 433.6 422.28 455.03 386.73 506.7 283.38 399.61 489.59 346.51 287.93 435.67 421.86 451.34 386.13 501.13 1 1 1 1 1 1 1 1 1 1 156055 18 21464 22495 161295 161295 36 MYYFGIAALDR 11 Arg10 _MYYFGIAALDR(ar)_ MYYFGIAALDR(1) MYYFGIAALDR(79.15) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 779.912 2 665.330408 1328.64626 72147.89 1.2872 0.00085643 172220 114.58 172220 114.58 779.911824398911 176.15 0.61172 176.15 175.97 176.58 0 25 12 3 0.786121726036072 0.00105084152892232 0.0540716834366322 0.0079983 1 92982 79.148 39.09 1 8874600 690.42 627.77 647.14 581.18 619.54 608.85 584.07 575.14 682.39 642.01 649.49 593.92 652.92 598.92 637.16 614.53 595.93 572.33 676.84 634.92 1 1 1 1 1 1 1 1 1 1 156056 18 21464 22495 161296 161296 36 MYYFGIAALDR 11 Arg10 _MYYFGIAALDR(ar)_ MYYFGIAALDR(1) MYYFGIAALDR(79.2) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 779.9117 2 665.330408 1328.64626 73369.47 1.2734 0.00084721 172220 114.58 172220 114.58 779.911014534657 176.46 0.37454 176.46 176.27 176.65 0 12 7 2 0.493444740772247 0.000233146085520275 0.00889732502400875 0.0079557 1 89459 79.201 32.015 1 6070500 462.69 626.68 372.9 373.73 515.15 434.73 373.83 319.59 374.34 297.02 434.91 592.09 381.32 397.83 518.53 435.85 385.21 319.93 372.79 295.16 1 1 1 1 1 1 1 1 1 1 156057 18 21464 22495 161297 161297 36 NAIFQLEK 8 Lys8+TMT6 _NAIFQLEK(ly)_ NAIFQLEK(1) NAIFQLEK(72.93) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 714.94 2 600.357483 1198.70041 NaN NaN NaN NaN NaN NaN NaN NaN 141.04 1 141.04 140.54 141.54 0 NaN NaN NaN 0.041605 1 74486 72.928 36.533 1 471.16 404.27 405.92 320.27 392.14 507.55 541.1 431.81 498.61 283.38 443.02 382.26 412.02 334.45 405.21 505.58 542.73 427.95 497.75 284.96 1 1 1 1 1 1 1 1 1 1 156380 2 21509 22545 161640 161640 NDIHTLLK 8 Lys8+TMT6 _NDIHTLLK(ly)_ NDIHTLLK(1) NDIHTLLK(78.15) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 473.9655 3 397.577714 1189.71131 88109.49 -0.022841 -9.0812E-06 192130 76.388 192130 76.388 473.965406335195 99.051 0.56441 99.051 98.658 99.222 0 28 11 3 0.634694814682007 0.00202299607917666 0.0280656851828098 0.0053405 1 47663 78.149 30.178 1 36666000 3448.5 3301.1 3374.2 2952.7 3657.1 2814.1 3718.4 3654.9 3227.9 3362.1 3244.8 3122.7 3397 3047.1 3737.8 2862.4 3765 3593.8 3228.3 3342 1 1 1 1 1 1 1 1 1 1 157377 278 21644 22684 162666 162666 801 NDIHTLLK 8 Lys8+TMT6 _NDIHTLLK(ly)_ NDIHTLLK(1) NDIHTLLK(76.68) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 473.9654 3 397.577714 1189.71131 89094.67 -0.44197 -0.00017572 192130 76.388 192130 76.388 473.965315497222 99.988 0.66124 99.988 99.555 100.22 7.6294E-06 26 14 3 0.479820907115936 0.00195171299856156 0.0301859471946955 0.0059705 1 47952 76.679 20.873 1 60868000 2871.3 2718.9 2575.8 3164.2 3022.7 2518.1 3103.2 2931.8 2907.5 2689.9 2700.4 2574.8 2609.9 3216.5 3077 2573.4 3144.2 2890.4 2900.9 2674 1 1 1 1 1 1 1 1 1 1 157378 278 21644 22684 162667 162667 801 NDIHTLLK 8 Lys8+TMT6 _NDIHTLLK(ly)_ NDIHTLLK(1) NDIHTLLK(76.06) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 473.9653 3 397.577714 1189.71131 90461.3 -0.50387 -0.00020033 192130 76.388 192130 76.388 474.300195679241 99.471 0.60928 99.471 98.965 99.574 0 23 12 2 0.584965229034424 0.00248338142409921 0.0940930023789406 0.006234 1 46018 76.064 25.612 1 26130000 5428.3 5172.8 4712.3 4616.6 4759 4127.6 5007.8 4908.6 4842.8 4521.1 5104.3 4893.2 4781.6 4763.1 4885.3 4201.1 5071.7 4837 4827.5 4493.9 1 1 1 1 1 1 1 1 1 1 157379 278 21644 22684 162668 162668 801 NDIHTLLK 8 Lys8+TMT6 _NDIHTLLK(ly)_ NDIHTLLK(1) NDIHTLLK(56.43) 0 0 1 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_03 M4R3 473.9657 3 397.577714 1189.71131 89133.8 0.45931 0.00018261 192130 76.388 192130 76.388 473.965281618618 99.198 0.64542 99.198 98.931 99.577 0 33 13 4 0.601843297481537 0.00343925505876541 0.0639517232775688 0.030694 1 48204 56.432 10.603 1 38597000 4798.4 3816.6 3742.7 4016.4 4469.9 4226.8 4273 4504.5 3933.5 4122.2 4509.6 3612.6 3833.2 4110.1 4542.4 4270.9 4340.8 4451.5 3926.8 4098.1 1 1 1 1 1 1 1 1 1 1 157380 278 21644 22684 162669 162669 801 NLDEQLSAPK 10 Lys8+TMT6 _NLDEQLSAPK(ly)_ NLDEQLSAPK(1) NLDEQLSAPK(135.1) 0 0 1 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 790.9625 2 676.379143 1350.74373 71804.6 1.0555 0.00071393 169400 114.58 169410 114.58 790.961134634376 109.16 0.37769 109.16 108.99 109.37 0 12 7 2 0.95301753282547 0.000152843407704495 0.0026592721696943 7.5777E-05 1 53449 135.1 90.345 1 5040200 758.84 774.94 631.58 644.4 823.24 785.44 758.4 807.33 760.26 700.03 713.4 732.87 643.96 669.2 832.77 789.74 772.6 798.02 757.08 697.07 1 1 1 1 1 1 1 1 1 1 160895 18 22110 23168 166303 166303 50 NLDEQLSAPK 10 Lys8+TMT6 _NLDEQLSAPK(ly)_ NLDEQLSAPK(1) NLDEQLSAPK(110.64) 0 0 1 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_01 M4R1 790.962 2 676.379143 1350.74373 71424.04 1.3129 0.000888 169400 114.58 169410 114.58 790.960721754917 109.69 0.31341 109.69 109.51 109.82 -7.6294E-06 9 6 2 0.234114199876785 0.000130051615997218 0.00152077246457338 0.00053794 1 53687 110.64 55.861 1 4672800 579.64 587.21 523.17 719.83 512.68 516.84 693.81 717.52 603.27 670.92 545.16 556.22 529.29 729.61 529.15 532.26 695.74 704.63 603.31 666.59 1 1 1 1 1 1 1 1 1 1 160896 18 22110 23168 166304 166304 50 NLVLAGIK 8 Lys8+TMT6 _NLVLAGIK(ly)_ NLVLAGIK(1) NLVLAGIK(88.82) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_01 M1R1 647.441 2 532.859661 1063.70477 NaN NaN NaN NaN NaN NaN NaN NaN 142.86 1 142.86 142.36 143.36 0 NaN NaN NaN 0.015222 1 69733 88.819 34.614 1 1694.5 1730.8 2209 1997.7 1817.4 1498.5 2133.7 2060.7 1726.9 1992.2 1597.5 1639 2184.3 2030.9 1893 1540.2 2147.3 2025.2 1731.1 1977.5 1 1 1 1 1 1 1 1 1 1 162203 2 22295 23361 167663 167663 11 NWSQCVELAR 10 Arg10 _NWSQCVELAR(ar)_ NWSQCVELAR(1) NWSQCVELAR(77.12) 1 0 0 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_02 M1R2 751.3871 2 636.805088 1271.59562 74750.75 0.92728 0.0005905 179930 114.58 179930 114.58 751.386625500517 116.92 0.71084 116.92 116.63 117.34 0 23 14 3 0.287098407745361 0.000156043111928739 0.00828745309263468 0.011377 1 56280 77.124 49.82 1 7108900 625.66 762.46 546.48 629.34 740.01 560.63 658.63 532.63 515.84 388.93 588.34 721.05 555.35 652.48 747.02 568.39 669.72 526.55 517.69 389.51 1 1 1 1 1 1 1 1 1 1 167083 2 22975 24070 172700 172700 1 NWSQCVELAR 10 Arg10 _NWSQCVELAR(ar)_ NWSQCVELAR(1) NWSQCVELAR(63.47) 1 0 0 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 751.3879 2 636.805088 1271.59562 74236.44 1.0733 0.00068348 179930 114.58 179930 114.58 751.387293530381 117.12 0.51795 117.12 116.83 117.34 7.6294E-06 20 10 3 0.398767501115799 0.000371424452168867 0.0144569873809814 0.042914 1 58390 63.473 26.916 1 8405600 238.42 0 270.7 115.07 190.14 266.22 0 257.4 238.17 0 224.55 0 269.47 112.66 197.62 263.4 0 251.24 230.56 0 1 0 1 1 1 1 0 1 1 0 167084 2 22975 24070 172701 172701 1 NWSQCVELAR 10 Arg10 _NWSQCVELAR(ar)_ NWSQCVELAR(1) NWSQCVELAR(62.69) 1 0 0 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 751.3862 2 636.805088 1271.59562 75247.02 1.0689 0.00068067 179930 114.58 179930 114.58 751.386186600262 116.53 0.75912 116.53 116.23 116.99 -7.6294E-06 22 15 2 0.702279686927795 0.000246060371864587 0.00374399218708277 0.045123 1 56893 62.694 34.87 1 6618800 188.18 232.13 264.23 222.87 260.19 307.9 414.05 159.63 196.06 250.01 177.52 219.64 260.58 229.69 269.24 306.62 410.83 164.17 201.32 245.55 1 1 1 1 1 1 1 1 1 1 167085 2 22975 24070 172702 172702 1 SDLQMAVLSFEK 12 Lys8+TMT6 _SDLQMAVLSFEK(ly)_ SDLQMAVLSFEK(1) SDLQMAVLSFEK(66.02) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 612.3489 3 535.626404 1603.85738 79616.08 0.87201 0.00046707 142610 76.388 142610 76.388 612.348513562499 176.97 0.67659 176.97 176.81 177.49 0 27 13 4 0.963715612888336 0.0026482380926609 0.0366497337818146 0.0091271 1 90978 66.023 27.785 1 15164000 1925.7 1914.4 1456.1 1799.4 2019.9 1792.5 1925.4 1938.3 2038.5 2080.9 1809.6 1811.3 1496.7 1852 2038.5 1815.7 1960.3 1919.7 2026.9 2059.9 1 1 1 1 1 1 1 1 1 1 189312 2 26470 27675 195665 195665 12 SDLQMAVLSFEK 12 Lys8+TMT6 _SDLQMAVLSFEK(ly)_ SDLQMAVLSFEK(1) SDLQMAVLSFEK(108.72) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 612.0149 3 535.626404 1603.85738 78237.12 0.76409 0.00040927 142610 76.388 142610 76.388 612.348376889624 176.05 0.61121 176.05 175.88 176.49 0 28 12 4 0.754151165485382 0.00173585372976959 0.036614615470171 0.00012915 1 92858 108.72 38.996 1 15493000 3092.7 2668.7 2895.6 2504.2 2655.1 3030.5 2985.5 2623.4 2570.9 3237.5 2909.3 2525 2921 2581.3 2743.9 3043.2 3011.4 2623.2 2571.9 3194.5 1 1 1 1 1 1 1 1 1 1 189313 2 26470 27675 195666 195666 12 SDLQMAVLSFEK 12 Lys8+TMT6 _SDLQMAVLSFEK(ly)_ SDLQMAVLSFEK(1) SDLQMAVLSFEK(55.1) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 612.3481 3 535.626404 1603.85738 77206.45 0.90335 0.00048386 142610 76.388 142610 76.388 612.014190917634 176.42 0.56314 176.42 176.13 176.69 0 18 11 3 0.726398348808289 0.000401166413212195 0.00926802027970552 0.027301 1 89463 55.105 11.603 1 9941900 2726.3 2761.4 2679.5 2965.7 2908.1 3001.6 2471.6 3040.2 2936.5 2949.9 2565.3 2614 2696.8 3030.9 2966 3034.8 2534 3011.6 2911.5 2927.9 1 1 1 1 1 1 1 1 1 1 189314 2 26470 27675 195667 195667 12 SDLQMAVLSFEK 12 Lys8+TMT6 _SDLQMAVLSFEK(ly)_ SDLQMAVLSFEK(1) SDLQMAVLSFEK(61.11) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_03 M4R3 612.0153 3 535.626404 1603.85738 74160.14 1.0052 0.00053841 142610 76.388 142620 76.388 612.014588780261 176.23 0.41847 176.23 175.97 176.39 0 21 8 3 0.730230033397675 0.00157537776976824 0.0720025524497032 0.014563 1 93455 61.11 10.757 1 16202000 1912.9 1843.5 1760.1 1915.2 2140.6 1696.3 2015.3 2139.8 2034.3 1863.3 1799.3 1744.9 1780.7 1959 2172.9 1728.6 2051.4 2103.7 2025.4 1855.2 1 1 1 1 1 1 1 1 1 1 189315 2 26470 27675 195668 195668 12 SDLQMAVLSFEK 12 Lys8+TMT6 _SDLQMAVLSFEK(ly)_ SDLQMAVLSFEK(1) SDLQMAVLSFEK(103.44) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 612.3488 3 535.626404 1603.85738 81277.51 0.80619 0.00043182 142610 76.388 142610 76.388 612.014482582498 175.48 0.47145 175.48 175.31 175.78 0 18 9 3 0.837686896324158 0.000587253307458013 0.0133759062737226 0.00019771 1 95010 103.44 45.267 1 18944000 2756.4 2960.2 2966.9 2781.8 2923.1 2809.7 3439.7 3260.9 2723.6 2803.6 2595.1 2800.8 2967.5 2863.5 3009.6 2846.1 3460.4 3212.1 2732.3 2792.4 1 1 1 1 1 1 1 1 1 1 189316 2 26470 27675 195669 195669 12 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(127.87) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_01 M1R1 753.9368 2 639.355137 1276.69572 69755.32 0.14225 9.0947E-05 179210 114.58 179210 114.58 753.936955632504 101.4 0.41304 101.4 101.22 101.63 0 14 8 2 1 0.000123774283565581 0.0011805355316028 0.00010058 1 46764 127.87 78.887 1 8594400 2252.2 1718.6 1639.5 1902.7 1876.4 2072.5 1790.1 1510.3 2118.2 1862.1 2116 1627.2 1688.4 1942.6 1910.8 2082.9 1826 1520 2100.4 1837.3 1 1 1 1 1 1 1 1 1 1 204421 2 28627 29928 211323 211323 13 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(71.15) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_02 M1R2 753.9363 2 639.355137 1276.69572 74216.85 0.51237 0.00032758 179210 114.58 179220 114.58 753.936871269977 100.57 0.94434 100.57 99.929 100.87 0 30 22 2 0.563850581645966 0.00026395617169328 0.00305578415282071 0.024558 1 46964 71.153 27.345 1 3867200 688.61 949.16 801.51 922.07 842.4 905.36 786.24 916.78 847.24 943.18 648.66 898.15 798.35 947.2 861.57 916.42 801.43 909.04 842.05 934.67 1 1 1 1 1 1 1 1 1 1 204422 2 28627 29928 211324 211324 13 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(134.13) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_02 M2R2 753.9349 2 639.355137 1276.69572 70929.45 0.45355 0.00028998 179210 114.58 179210 114.58 753.936720943597 101.3 0.52285 101.3 100.99 101.52 0 19 10 3 0.638036847114563 0.000280198350083083 0.00343178049661219 7.6979E-05 1 48781 134.13 81.414 1 11085000 1514.9 1678.4 1384.2 1651.2 1778.7 1476.6 1556.8 1553.9 1478.6 1426.9 1424.8 1588.3 1401.6 1694.1 1799.5 1499.8 1588.3 1536.2 1474.7 1418.4 1 1 1 1 1 1 1 1 1 1 204423 2 28627 29928 211325 211325 13 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(91.12) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 753.937 2 639.355137 1276.69572 73990.82 -0.36084 -0.0002307 179220 114.58 179210 114.58 753.937172991331 100.55 0.82946 100.55 99.905 100.73 0 24 19 2 0.320641219615936 0.000166553858434781 0.00143647473305464 0.0031853 1 46598 91.123 38.72 1 3271000 1444.2 1398.6 1451.3 1431.1 1414.8 1459.3 1411.6 1750.6 1637.8 1329.9 1359.1 1323.7 1457.7 1466.3 1454.4 1478.1 1436.7 1720 1624.7 1330 1 1 1 1 1 1 1 1 1 1 204424 2 28627 29928 211326 211326 13 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(92.11) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_01 M3R1 753.9371 2 639.355137 1276.69572 72397.78 0.37024 0.00023671 179210 114.58 179220 114.58 753.937275300351 101.71 0.49183 101.71 101.45 101.94 0 15 10 2 0.379092693328857 0.000161883406690322 0.00185874802991748 0.0028464 1 50608 92.112 43.131 1 6995300 911.58 1317.3 1160.9 1047.9 1060.7 1291.9 1215.6 1207 1211.9 1168 859.25 1245.6 1149.9 1091.5 1096.7 1297.2 1227.9 1198.6 1207 1159.4 1 1 1 1 1 1 1 1 1 1 204425 2 28627 29928 211327 211327 13 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(88.34) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 753.9373 2 639.355137 1276.69572 74950.42 0.59707 0.00038174 179210 114.58 179220 114.58 753.937016231085 100.9 0.42225 100.9 100.59 101.01 -7.6294E-06 10 8 2 0.611127257347107 0.000222487811697647 0.00412716763094068 0.0041398 1 46977 88.338 39.544 1 3965600 944.79 843.02 1023.6 770.26 1254 1103.8 1178.7 1129.3 1024.8 1190.7 889.55 797.52 1024.8 796.38 1272.5 1106 1197.3 1119.9 1024.9 1179.2 1 1 1 1 1 1 1 1 1 1 204426 2 28627 29928 211328 211328 13 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(82.5) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_03 M3R3 753.9368 2 639.355137 1276.69572 74916.47 0.24181 0.00015461 179220 114.58 179220 114.58 754.438781965477 100.52 0.32693 100.52 100.33 100.65 0 10 6 2 0.311833471059799 0.00021309859585017 0.00307444459758699 0.0075205 1 49508 82.505 28.348 1 15084000 851.1 712.47 874.22 527.25 1200.4 631.41 1034.7 1050.8 970.36 787.39 801.07 673.54 878.84 551.83 1210.7 640.75 1056.2 1025 968.16 787.83 1 1 1 1 1 1 1 1 1 1 204427 2 28627 29928 211329 211329 13 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(119.03) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_02 M4R2 753.9367 2 639.355137 1276.69572 73768.16 0.16814 0.0001075 179210 114.58 179210 114.58 753.936670844868 100.87 0.6374 100.87 100.54 101.18 0 16 13 2 0.759675860404968 0.00058706832351163 0.0053684082813561 0.00030269 1 48778 119.03 63.658 1 14349000 1162.1 1324.1 1321 1408.3 1355.1 1252.1 1535.9 1359.6 1285.6 1546.2 1094.5 1253.4 1317.3 1438.8 1391.2 1273.5 1548.3 1347.9 1287.3 1528.5 1 1 1 1 1 1 1 1 1 1 204428 2 28627 29928 211330 211330 13 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(43.77) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 502.9598 3 426.572517 1276.69572 82365.33 -0.14848 -6.3337E-05 179070 76.388 179070 76.388 502.95990583715 100.08 0.61889 100.08 99.806 100.43 0 17 12 2 0.43366876244545 0.000331894640112296 0.00216389237903059 0.063738 1 50053 43.77 12.484 1 10018000 587.74 795.28 752.96 509.4 580.91 555.52 852.68 610.21 702.21 398.69 554.03 751.52 744.97 538.72 609.98 560.52 852.47 599.89 703.51 400.98 1 1 1 1 1 1 1 1 1 1 204429 2 28627 29928 211331 211331 13 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(113.38) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_02 M5R2 753.9369 2 639.355137 1276.69572 76424.24 0.44878 0.00028693 179210 114.58 179210 114.58 753.93657344953 100.76 0.37148 100.76 100.58 100.95 0 11 7 2 0.689778089523315 0.000511861580889672 0.00980012677609921 0.00045805 1 47455 113.38 62.033 1 7715100 972.88 1308.9 1331.1 1365 1432.8 1146.7 1174.1 1342.9 1088.2 1189.6 917.55 1238.9 1315.1 1395.5 1461.4 1169.4 1201 1323 1086.1 1183.8 1 1 1 1 1 1 1 1 1 1 204430 2 28627 29928 211332 211332 13 SYTAADATLK 10 Lys8+TMT6 _SYTAADATLK(ly)_ SYTAADATLK(1) SYTAADATLK(122.7) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 753.9365 2 639.355137 1276.69572 74881.38 0.45567 0.00029134 179210 114.58 179220 114.58 753.93704057852 100.42 0.51859 100.42 100.06 100.58 0 15 10 2 0.527959704399109 0.000337926583597437 0.00576616637408733 0.00021875 1 47627 122.7 73.905 1 7104500 1341.4 1163.2 1430.1 1378.4 1693.8 1438.3 1394.9 1304.4 1322.5 1442.4 1262.9 1101.6 1432.8 1402.3 1719.1 1451 1427 1299.5 1319.1 1426.8 1 1 1 1 1 1 1 1 1 1 204431 2 28627 29928 211333 211333 13 TVSYLGLE 8 Unmodified _TVSYLGLE_ 0 0 0 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_01 M1R1 555.8164 2 441.234376 880.454199 81995.81 0.85053 0.00037528 259680 114.58 259680 114.58 555.815727261812 161.87 0.62863 161.87 161.47 162.09 1.5259E-05 29 16 4 0.885923326015472 0.00168972602114081 0.00627311924472451 0.0058424 1 80536 93.374 66.12 1 54382000 3244.7 3160.4 3614.2 3410.5 3146.6 3258.1 3461 3236.6 3287.3 3405.9 3055.6 2991.8 3605.2 3483.4 3261.9 3300.1 3498.5 3212.4 3278.6 3373.2 1 1 1 1 1 1 1 1 1 1 219090 104 30596 31998 226515 226515 TVSYLGLE 8 Unmodified _TVSYLGLE_ 0 0 0 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_03 M1R3 555.8162 2 441.234376 880.454199 82564.66 0.68673 0.00030301 259680 114.58 259680 114.58 555.815900549217 161.29 0.59229 161.29 160.96 161.55 0 26 13 3 0.956202805042267 0.000638874946162105 0.00237743672914803 0.0037047 1 84087 98.523 71.83 1 61019000 2015.3 2228.8 2145.6 1947.5 1979.7 2230.2 2079.8 2424.1 2134 2195.5 1897.2 2108.2 2146.7 2015.2 2043.3 2248.5 2108.4 2393.8 2123.7 2183.3 1 1 1 1 1 1 1 1 1 1 219091 104 30596 31998 226516 226516 TVSYLGLE 8 Unmodified _TVSYLGLE_ 0 0 0 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 555.8163 2 441.234376 880.454199 82660.87 0.87833 0.00038755 259680 114.58 259680 114.58 555.81583388372 161.31 0.51213 161.31 161.01 161.53 0 19 10 3 0.963020145893097 0.000676663999911398 0.00290881213732064 0.010197 1 80989 87.181 63.226 1 64760000 1906.7 1948.5 2080 1872.3 2056.7 2041.5 1699.9 1822.2 1706.9 1615.9 1795.3 1843.7 2078.8 1925.9 2108.1 2055.2 1740.3 1809.8 1699.6 1607.9 1 1 1 1 1 1 1 1 1 1 219092 104 30596 31998 226517 226517 TVSYLGLE 8 Unmodified _TVSYLGLE_ 0 0 0 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 555.816 2 441.234376 880.454199 85214.61 0.6119 0.00026999 259680 114.58 259680 114.58 555.815752992525 161.36 0.65596 161.36 160.99 161.64 0 25 14 2 0.974405765533447 0.00158609682694077 0.00596100930124521 0.0020055 1 80845 106.36 79.102 1 50450000 2601.5 2900.4 2811.2 3047.1 2862.9 3114.6 2980.2 3079.9 3184.9 3195.1 2449.4 2745.3 2811.6 3117.9 2937.1 3147.5 3024.1 3056.5 3166.1 3165.6 1 1 1 1 1 1 1 1 1 1 219093 104 30596 31998 226518 226518 TVSYLGLE 8 Unmodified _TVSYLGLE_ 0 0 0 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_03 M3R3 555.8162 2 441.234376 880.454199 82686.02 0.95549 0.00042159 259680 114.58 259680 114.58 555.815654773322 161.11 0.763 161.11 160.67 161.44 0 29 18 3 0.994215071201324 0.00232674367725849 0.0117064360529184 0.0037187 1 85217 98.458 70.687 1 76808000 2623.7 2550.5 2507.5 2643.1 2727.5 2549.7 2576.7 2511.8 2475 2395.6 2468.4 2414 2528.4 2705.3 2784.7 2580.8 2620.5 2489.6 2467.6 2378.8 1 1 1 1 1 1 1 1 1 1 219094 104 30596 31998 226519 226519 VCPTTETIYNDEFYTK 16 Lys8+TMT6 _VCPTTETIYNDEFYTK(ly)_ VCPTTETIYNDEFYTK(1) VCPTTETIYNDEFYTK(110.97) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_01 M3R1 816.4149 3 740.027073 2217.05939 70752.47 1.1586 0.00085739 103220 76.387 103220 76.388 816.748525099941 154.5 0.56993 154.5 154.23 154.8 1.5259E-05 26 11 4 0.595954656600952 0.00115260132588446 0.0205412358045578 1.3478E-05 1 81141 110.97 80.397 1 16816000 386.62 350.53 302.79 245.5 370.27 532.18 265.35 267.71 442.69 266.81 363.36 331.32 310.06 259.59 374.74 524.8 276.35 273.3 435.94 264.62 1 1 1 1 1 1 1 1 1 1 222319 2 31039 32460 229865 229865 14 VCPTTETIYNDEFYTK 16 Lys8+TMT6 _VCPTTETIYNDEFYTK(ly)_ VCPTTETIYNDEFYTK(1) VCPTTETIYNDEFYTK(64.59) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_01 M4R1 816.7519 3 740.027073 2217.05939 65698.38 1.3664 0.0010112 103220 76.387 103220 76.388 816.748624601552 154.51 0.38129 154.51 154.37 154.75 1.5259E-05 17 7 3 0.455241501331329 0.00102553854230791 0.0118118738755584 0.0056882 1 79031 64.588 40.953 1 13060000 981.37 779.49 736.38 833.3 856.43 823.66 724.84 652.4 797.99 664.05 922.16 737.88 756.46 851.69 870.3 830.74 742.31 652.13 792.67 658.24 1 1 1 1 1 1 1 1 1 1 222320 2 31039 32460 229866 229866 14 VDMLSEINIAPR 12 Arg10 _VDMLSEINIAPR(ar)_ VDMLSEINIAPR(1) VDMLSEINIAPR(108.31) 1 0 0 0 0 A5YKK6 A5YKK6 A5YKK6 CNOT1 CCR4-NOT transcription complex subunit 1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_03 M5R3 532.967 3 456.579078 1366.7154 88430.61 0.65846 0.00030064 167300 76.387 167300 76.388 532.966696748179 170.36 0.41718 170.36 169.99 170.41 0 10 8 2 0.551481783390045 0.000200815251446329 0.00458481814712286 0.00010496 1 87527 108.31 81.265 1 4007800 1293 741.56 1413.8 1232.2 1125.9 1207.6 1056.7 931.89 1237.6 1259.1 1217.5 703.67 1411.2 1236.5 1172.1 1218.9 1078.4 937.53 1227.4 1240 1 1 1 1 1 1 1 1 1 1 223234 18 31150 32575 230809 230809 37 VVQTDETAR 9 Arg10 _VVQTDETAR(ar)_ VVQTDETAR(1) VVQTDETAR(79.07) 1 0 0 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture1_02 M1R2 629.3474 2 514.765955 1027.51736 78200.6 0.97502 0.00050191 222590 114.58 222590 114.58 629.347190066924 49.411 0.38156 49.411 49.161 49.543 0 12 7 2 0.305933803319931 0.000366959720849991 0.011392897926271 0.011408 1 19684 79.07 36.732 1 1546800 450.04 265.29 519.94 532.15 450.41 445.08 411.72 296.05 370.18 564.33 423.91 252.09 517.55 530.42 466.02 451.49 418.9 302.37 369.82 552.55 1 1 1 1 1 1 1 1 1 1 239736 2 33385 34914 247808 247808 2 VVQTDETAR 9 Arg10 _VVQTDETAR(ar)_ VVQTDETAR(1) VVQTDETAR(90.15) 1 0 0 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 629.3485 2 514.765955 1027.51736 NaN NaN NaN NaN NaN NaN NaN NaN 49.965 1 49.965 49.465 50.465 0 NaN NaN NaN 0.0092268 1 19645 90.149 50.896 1 582.3 623.97 772.24 471.25 486.29 605.97 410.24 607.28 384.75 683.38 549.04 589.91 762.09 492.79 515.32 608.67 419.15 603.3 383.87 675.7 1 1 1 1 1 1 1 1 1 1 239737 2 33385 34914 247809 247809 2 VVQTDETAR 9 Arg10 _VVQTDETAR(ar)_ VVQTDETAR(1) VVQTDETAR(82.26) 1 0 0 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 629.3484 2 514.765955 1027.51736 NaN NaN NaN NaN NaN NaN NaN NaN 48.797 1 48.797 48.297 49.297 0 NaN NaN NaN 0.015015 1 19153 82.261 50.839 1 238.65 204.74 101.7 178.43 223.74 265.8 278.42 132.77 0 63.36 223.82 193.65 111.73 185.07 223.05 263.73 276.16 134.47 0 64.672 1 1 1 1 1 1 1 1 0 1 239738 2 33385 34914 247810 247810 2 VVQTDETAR 9 Arg10 _VVQTDETAR(ar)_ VVQTDETAR(1) VVQTDETAR(72.2) 1 0 0 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_03 M3R3 629.348 2 514.765955 1027.51736 NaN NaN NaN NaN NaN NaN NaN NaN 49.084 1 49.084 48.584 49.584 0 NaN NaN NaN 0.039924 1 20091 72.2 34.04 1 595.93 606.26 795.71 643.13 480.33 645.84 564.27 836.71 782.79 651.69 561.93 573.88 784.87 657.66 512.96 655.43 572.9 820.82 773.49 651.19 1 1 1 1 1 1 1 1 1 1 239739 2 33385 34914 247811 247811 2 VVQTDETAR 9 Arg10 _VVQTDETAR(ar)_ VVQTDETAR(1) VVQTDETAR(71.22) 1 0 0 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_03 M4R3 629.3482 2 514.765955 1027.51736 80355.71 0.76825 0.00039547 222590 114.58 222590 114.58 629.347299563552 49.034 0.39581 49.034 48.836 49.232 0 15 9 2 0.555457711219788 0.000340121041517705 0.00503637827932835 0.023708 1 19859 71.221 35.68 1 2320400 656.22 426.69 391.4 703.87 318.77 484.46 425.44 600.62 267.88 527.32 616.05 404.87 409.98 705.1 332.89 498.68 425.22 590.82 271.16 524.89 1 1 1 1 1 1 1 1 1 1 239740 2 33385 34914 247812 247812 2 VVQTDETAR 9 Arg10 _VVQTDETAR(ar)_ VVQTDETAR(1) VVQTDETAR(88.13) 1 0 0 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture5_01 M5R1 629.3483 2 514.765955 1027.51736 77340.94 0.63815 0.0003285 222590 114.58 222590 114.58 629.347609716872 48.355 0.77984 48.355 47.957 48.737 -3.8147E-06 26 17 2 0.763215363025665 0.0010706753237173 0.0152358114719391 0.0041991 1 20306 88.134 45.846 1 2038900 303.8 443.95 408.45 449.94 278.11 429.97 556.52 421.7 344.24 562.8 286.48 420.16 402.93 461.06 296.75 435.78 550.57 420.66 348.74 554.41 1 1 1 1 1 1 1 1 1 1 239741 2 33385 34914 247813 247813 2 WFCHIQHYPGIR 12 Arg10 _WFCHIQHYPGIR(ar)_ WFCHIQHYPGIR(1) WFCHIQHYPGIR(41.69) 1 0 0 0 0 O43324 O43324 O43324 EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_03 M2R3 463.9934 4 406.702378 1622.7804 99411.17 -0.51547 -0.00020964 140870 57.291 140870 57.291 464.244160409096 107.8 0.32216 107.8 107.61 107.94 0 12 7 3 0.777727544307709 0.000821783323772252 0.00363787729293108 0.05337 1 50762 41.689 15.572 1 19265000 3197.9 3278.4 3190.8 2844.5 3241.2 2992.2 2581.9 3546.1 2944.3 2811.8 3009.4 3100.9 3207 2942.8 3315.8 3027.6 2653.3 3487.2 2922.1 2807.9 1 1 1 1 1 1 1 1 1 1 241630 278 33650 35184 249776 249776 YDIDLPNK 8 Lys8+TMT6 _YDIDLPNK(ly)_ YDIDLPNK(1) YDIDLPNK(52.72) 0 0 1 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture2_01 M2R1 482.2839 3 405.561841 1213.66369 88227.38 0.35916 0.00014566 188350 76.388 188350 76.388 482.283895543023 136.92 0.63774 136.92 136.54 137.17 0 25 13 3 0.970517039299011 0.00145375053398311 0.0485036820173264 0.038787 1 68038 52.716 8.3985 1 17244000 3547.7 4102.7 3784.9 3368.4 3751.5 4021 3586.1 3752.2 3783.1 3497.1 3340 3879.8 3787.7 3500.4 3850.8 4040.4 3650.5 3724 3762.1 3474.9 1 1 1 1 1 1 1 1 1 1 245202 104 34099 35654 253494 253494 YDIDLPNK 8 Lys8+TMT6 _YDIDLPNK(ly)_ YDIDLPNK(1) YDIDLPNK(54.61) 0 0 1 0 0 O00244 O00244 O00244 ATOX1 Copper transport protein ATOX1 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture3_02 M3R2 481.9497 3 405.561841 1213.66369 89530.23 0.29417 0.0001193 188350 76.388 188350 76.388 481.949431561221 135.35 0.66937 135.35 134.87 135.54 0 27 13 3 0.966034054756165 0.0010257251560688 0.029427682980895 0.034658 1 65957 54.611 11.982 1 10499000 3065.6 3112.5 3116.7 3502.4 3432.9 3080.7 3612.8 3030.7 3101.8 2974.9 2885.2 2947 3130.3 3568.1 3507.1 3128.5 3652.8 3005.4 3103.3 2951.7 1 1 1 1 1 1 1 1 1 1 245203 104 34099 35654 253495 253495 YVLGDTAMQK 10 Lys8+TMT6 _YVLGDTAMQK(ly)_ YVLGDTAMQK(1) YVLGDTAMQK(103.08) 0 0 1 0 0 A0AVT1 A0AVT1 A0AVT1 UBA6 Ubiquitin-like modifier-activating enzyme 6 MULTI-MSMS 161117_SILAC_HeLa_UPS1_TMT10_Mixture4_01 M4R1 796.4564 2 681.87264 1361.73073 70254.26 1.2993 0.00088592 168040 114.58 168040 114.58 796.453252543538 128.03 0.7942 128.03 127.85 128.64 0 33 18 3 0.592841506004334 0.000338472134899348 0.00606613606214523 0.00098021 1 64067 103.08 41.603 1 17979000 1565.1 1676.8 1441.3 1433.1 1462.8 1363.3 1579.2 1601.7 1317.4 1303.5 1472.1 1585.9 1456.4 1483.1 1501.7 1383.8 1594.6 1576 1319.3 1300.6 1 1 1 1 1 1 1 1 1 1 252395 2 35093 36681 260943 260943 15