Mercurial > repos > haydensun > manorm
diff README.rst @ 2:30cdbc4faefa draft default tip
Update galaxy tool to v1.0.1
author | haydensun |
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date | Wed, 24 Jan 2018 02:42:53 -0500 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/README.rst Wed Jan 24 02:42:53 2018 -0500 @@ -0,0 +1,53 @@ +Galaxy Wrapper for MAnorm +========================= + +Introduction +------------ + +ChIP-Seq is widely used to characterize genome-wide binding patterns of +transcription factors and other chromatin-associated proteins. Although +comparison of ChIP-Seq data sets is critical for understanding cell +type-dependent and cell state-specific binding, and thus the study of +cell-specific gene regulation, few quantitative approaches have been +developed. + +Here, we present a simple and effective method, MAnorm, for quantitative +comparison of ChIP-Seq data sets describing transcription factor binding +sites and epigenetic modifications. The quantitative binding differences +inferred by MAnorm showed strong correlation with both the changes in +expression of target genes and the binding of cell type-specific +regulators. + +Installation +------------ + +Please search and install MAnorm galaxy tool via the `Galaxy Tool Shed`_. + +.. _`Galaxy Tool Shed`: https://toolshed.g2.bx.psu.edu/view/haydensun/manorm + +Documentation +------------- +To see the full documentation of MAnorm, please refer to: http://manorm.readthedocs.io/en/latest/ + +ChangeLog +--------- +- v1.0.1: Fix an incorrect file name, related to MAnorm-v1.1.3 +- v1.0: Initial release, related to MAnorm-v1.1.2 + + +Links +----- +The Python version of MAnorm is developed by ShaoLab_ at `CAS-MPG Partner Institute for Computational Biology, SIBS, CAS`_. + +GitHub: https://github.com/shao-lab/MAnorm + +.. _ShaoLab: http://bioinfo.sibs.ac.cn/shaolab/ +.. _CAS-MPG Partner Institute for Computational Biology, SIBS, CAS: http://www.picb.ac.cn/picb/indexeng.jsp + + + + + + + +