Mercurial > repos > haydensun > manorm
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Update galaxy tool to v1.0.1
author | haydensun |
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date | Wed, 24 Jan 2018 02:42:53 -0500 |
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Galaxy Wrapper for MAnorm ========================= Introduction ------------ ChIP-Seq is widely used to characterize genome-wide binding patterns of transcription factors and other chromatin-associated proteins. Although comparison of ChIP-Seq data sets is critical for understanding cell type-dependent and cell state-specific binding, and thus the study of cell-specific gene regulation, few quantitative approaches have been developed. Here, we present a simple and effective method, MAnorm, for quantitative comparison of ChIP-Seq data sets describing transcription factor binding sites and epigenetic modifications. The quantitative binding differences inferred by MAnorm showed strong correlation with both the changes in expression of target genes and the binding of cell type-specific regulators. Installation ------------ Please search and install MAnorm galaxy tool via the `Galaxy Tool Shed`_. .. _`Galaxy Tool Shed`: https://toolshed.g2.bx.psu.edu/view/haydensun/manorm Documentation ------------- To see the full documentation of MAnorm, please refer to: http://manorm.readthedocs.io/en/latest/ ChangeLog --------- - v1.0.1: Fix an incorrect file name, related to MAnorm-v1.1.3 - v1.0: Initial release, related to MAnorm-v1.1.2 Links ----- The Python version of MAnorm is developed by ShaoLab_ at `CAS-MPG Partner Institute for Computational Biology, SIBS, CAS`_. GitHub: https://github.com/shao-lab/MAnorm .. _ShaoLab: http://bioinfo.sibs.ac.cn/shaolab/ .. _CAS-MPG Partner Institute for Computational Biology, SIBS, CAS: http://www.picb.ac.cn/picb/indexeng.jsp