# HG changeset patch # User iuc # Date 1630096492 0 # Node ID 7a82006f7c05f8056547bc60c587e7e1fed1bb88 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/artic commit dacdfa7ecfbdd1c1a12494cf7d0450185c122c84" diff -r 000000000000 -r 7a82006f7c05 artic_guppyplex.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/artic_guppyplex.xml Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,50 @@ + + Filter Nanopore reads by read length and (optionally) quality + + macros.xml + + + artic + + + + + + + + + + + + + + + + + + + + + + \ No newline at end of file diff -r 000000000000 -r 7a82006f7c05 macros.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/macros.xml Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,18 @@ + + 1.2.1 + + + + @misc{githubartic-ncov2019, + author = {Nick Loman and the ZiBRA Project and the ARTIC project}, + year = {2017}, + title = {ARTIC toolkit}, + publisher = {GitHub}, + journal = {GitHub repository}, + howpublished{\url{https://github.com/artic-network/fieldbioinformatics}}, + } + + + + + diff -r 000000000000 -r 7a82006f7c05 test-data/SRR11410539_seqtk_sample_500_1.fastq --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/SRR11410539_seqtk_sample_500_1.fastq Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,2000 @@ +@SRR11410539.882919 882919/1 +CTTGGGCATTAGTCGTTCAGTTACATGTACTAAGGTTAAACAGACGACTACAAACGGAATCCCGACAGCACCTACCAATAACTTTCAAATCGTAGTCTGTTCTCTAAATATGAACTTTAAAATCTGTGTGGCTGTCATCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAACTAATTACTGTCGTTGACAGGACACGAGTAACTCGTCATCTTCTGCAGGCTGCTTACGGTTCGTCCGTGTTGCAGCCGATCCTCTTTATCTAGGTTTGTCGGGTGTGACCGAAGGTAAGATGGAGAGCCTTGTCCCCTGGTTTCAACGAGAAAACACGTCCAGTTTGCCTGTTTTACAGGTTCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGAGTCTTATCAGAGCACGTCAACATCTTAAAGATGAGGGTGCTATTGGTTTTCCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACTTT ++ +$0%#%$##'*(&)&&*)0/09711$$$&&/3%%)*3;:<:99:;;992&6;DF;<$&,2%%6/8:64=D@B?>:37//.11%%%%'#%--($&%&)077AB:6A4/0.)'(+.223301344/3%'(*0169<,(3%''$%%,+5//,((,40=,8%$8@>?=/&&15676.0++)1335:<:?<;>9;>=A??6**5<830-%&)4//265/1'59:H@=>3//8:53/-13AE8;;=?B??B@/)+42.28122+*2/4//)<126,,.2,<9:,83$$-&9@<=6;@>54800+8=<70/6)*>9;EJBDE@0:24&'(4<::3)).,.,/1,&,&*,0C=@<=9?;7>>;77*+,)-),%&*//;>B?<72&'+* +@SRR11410539.1188960 1188960/1 +TATTACTACCATTCGTTCCCATGCCTTACTAAGGTCACTCGACCAACTCTGGCATGAATCGACAGCACGCGAAGTGCTCTGCCTATACAGTTGAACTCGGTACAGAAGTAAATGAGTTCGCCTGTGTTGTGGCAGATGCTGTCATAAAGCTTTTGGCAATCATCTGGATGCACCCACACCACTAGGCATTGATTTAGATAGTGGAGTATGGCTACATACTACTTGTTTGATGAGTCTGGTGAGTTTAAATTGGCTTCACATATGTATTGTTCTTTTTACCCTCAGATGAGGATGAAGAAGGTGATTGTGAAGAGAAGTTTGAGCCATCAAACTCAATATGAGTATGTAGTACTGAAGATGATTACCAAGGTAAACCTTTGGAATTTGGTGCGCACTTCTGCATCTTCAACTGAAGAGCAAGAAGAAGATTGGTTAGATCGAAGGTGCTGTCAATTCCGTTTGTAGTAATCTGTTTAACCTTAGCAATACGTAACTT ++ +#$#$$#$$%%%%'%&$$%)(%%###$%($%))('('%"$%#$#%#%"'-$"##$&%&*&086)%421$$*%&).6./8;:B@>D2:BF@21&+/?@C=80.B<=><1./15-101'*914,6=;?<=>:-.52261+((*'-065280,-.;-58@32?EDA8923<0:552:8;602<;03+.<:=:?3/0(1>?<(780@/4)--.%&&&-).<0.5&))&($'%5499<+&+$$%%.64<9;?970((+>6)$.&,0??C:;/ID>;=3?34,7:567>:67*2#&&.9;=D-=*<@DA65-//2=B:;3..-9?IKLCBDIDC@A+%,A?7878408;7:.--0./,*/145?<;;:()&73767:9224BB?<:846?AC9?;GB7;89;=CEBC:A@ABGCA@C+$$589??>CC@@7@A4756731-/091+6+,4/15>?9<;><8;=A;;81+<++??A6-;>;94*>-2877===6<00*&5%&/;>4*<9=;D430&)&$$%)+,.+*)-)@@F5336:?=?BGC?AE:AB=AB3.:=89622--,3B@@BC>>315-1B452847293200.,437;:8@:<8724$$(109;99::@?@D<<5;90;&5761>@9/-.)* +@SRR11410539.635976 635976/1 +GTTGTACTTCGTTCGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTCATGGCTGCATCACGGTCAAATTCAGATTGCCACATTCAAGACTTCTTCAACTTTTTAAGAACAACCAGAATCACCATTAGCAACAGCCTGCTCATAAGCTTCTTGAGCAGTAGCAAAAACTGCATATGATGGAAGGGAACTAAACTCTGAGGCTATAGCTTGTAAGGTTGCCCTGTTGTCCAGCATTTCTTCACAAAGCTTGTTTATGTCTACAGCACCCTGCATGGAAAGCAAAACAGAAAGTAGTGAAACCATTTTTCAGGCTTCAGTAGTATCTTTAGCTAAGGAATGTCATTGTGTAACTGGACACATTGAGCCCACAATTTAGATGATGATTCTACTCTGAGTTGTTGCAAAACTGAGAGTAAGACTACTGATGTGCAAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +*$%)35;=@;=H<,*1)9?@EI>I=@?'(5>IHEG93/3/6.+&%#$.269--<9=8:56168==FD>?,232,&%'*.2056<9:8:2+%1+2/'25:?@@:8-.--"#&/26F>?BI>B?A?A8C43/1&()+9HGDD89784447?>>9'3'+DB@CADB?;=,4,;A;A>?;<-?=<9<-4:4:>3-/&&)*8893>GF;93+8>67@))@B;C>?AC@C04,,-.'$$$0:>@CB;@>BC?@>GFEHI@;68:44546>?=AAHI@55=5=><34>@A:==@@>BF>.)*'9>?D;<6D:=5<-)&(<=A@@8//?A;?EC@DA&&($2/AA57;D??@;DFA<<='7DEEJ?=A6339:?A?AA?EA:EB;36;=23-C?B@B<8?=7717;9B?;:B;?C==A>BEFBA;3121=,7750/B><22$ +@SRR11410539.400371 400371/1 +CATCATTGTACTTCGTTCAGTTACATATTAGCACTAGGTTAAACAGACGACTACAAACCAGATCGACTTGCAGCACCTAGAATAACCTGGTAAGAATGAGTAAACTGGTGTTAAACGAAGTACAGTGAATGACATAAGGAATAGTAAAAGTATTAAGGCAACTACATGACTGTATTCACCAAGCTCTTCAGCCTCTTGAAATAGTGACATGAAACATGTTACTGATAGCTACAATACCAGCTACTATGAATACTGATGTATCCAGCACCAATAGGTTGAATTAGTGGTGTAAACATATTAGTAAAGTAAATTCTCAGCATCTACACCACAGAAAACTCTGGTAAAGATCCACAATAATCATTAGATACCCATCTACTAGTAGATACACAAACACCAACTTCTGATCTTTCACAAAGGTGCCGTGCCTACAGTACTCAGAAAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACGCCTTGTGCGTGCTT ++ +'&%%$')+)%567349/.*,(,)'*'(()''(&&*&$;469;1*-+3/0201-/24*&(0%&-+('''(#(+*+1//*('('$&%'')%('-/2;D26/=)*77/.-,>B=9464)#%&&))699CBDF>>=A-97950(+5/135620'734623/33./9@AE;DEC@CB=::7.*()*,2687<2*%&+)1'&)%,1/*-.-$$&'(+((&('%%.+#&')&$*'*///00-,>6D.77<992(%%'$$(*+,/+%$'%&*$*024A<+(/=H@<75<<;9;'+//34927+**,1-3967156'+,-+#'/0,840=300.,&(*('+0+,&&&$$&*-/%*,$$&#'$&%%%38**('$#*'88;@?@8**-+-544=:+'&'',1*%-4)*-1520@?>AFC/+..11%'2A?:<2688-*+(*0/./$-%'$#$%$% +@SRR11410539.2279751 2279751/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGTATTGCCCTATTTTTCTTCATAACTGGTAATACACTTCAGTGTATAATGCTAGTTTATTGTTTCTTAGGCTATTTTTGTACTTGTTACTTTGGCCTCTTTTGTTTACTCAACCGCTACTTTAGACTGACTCTTGAGTGTTTATGATTACTTGGTTTCTACAGGAGTTTAGATATGAATTTGCAGGGATATTTACTCCCACCAAGAATAGCATAGATGCCTTCAAACTCAACATTAAATTGTTGGGTGTTGGTGGCAAACCTTGTATCAAAGTAGCCACGCAGTCTAAAATGTCAGATGCTGAAGTGCACATCAGTAGTCTTACTCTCAGTTTGCAACAACTCAGTAGAATCATCATCTAAATTGTGGGCTCAATGTGTCCAGTTACAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACGTAAC ++ +&&*+/845>=:7F7667BBB;;6769%4<()6?FE@A<7;=>CDKEJ>;=>58'*&8:;7*27898>=715::=>?DBA6;?DJECCEFB;@EB>B@@H<3>=EJBIC:89;8=<=<;5@>GE;CA+><80--./'/8'$58?<;0'9?8?C@D70-:A486<>?=<>80%$'$+-(%(+(..%$$&'&%),&(&((,((349-4%&*3898B:;7>,??@,<=D?@GGNK@BBDI?FG;=BACB@>>@78@AB=;=??99=:?DFG>1=--*$()'%1)9-EE?H?0'5/456-')*''%19>0@-)4*('..88:<37<10,'947C:99?*/)(15.2/:76=;>=C827448<<=?CH:6:>?AB@55=79AB97&',?C98>3;CBFLD9;9GFKDGDB:;1/<5=:<;11.+*+(05<<6,$ +@SRR11410539.1984739 1984739/1 +CATTAGCTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAACGACAGCACCTAAAGGTGTCTGCAATTCATAGCTCTTTCAGAACGTTCCGTGTACCAAGCAATTTCATGCTCATGTTCACGGCAGCAGTATACACCCCTCTTAGTGTCAATAAAGTCCAGTTGTTCGGACAAAGTGCATGAAGCTACCAGCACGTCTAGAAGGTCTTTAATGCACTCAAGAGGTAGCCATCAGGGCCACAGAAGTTGTTATCGACATAGCGAGTGTATGCCCTCCGTTAAGCTCACGCATGAGTTCACGGGTACACCACTGCTATGTTTAGTGTTCCAGTTTTCTTGAAAATCTTCATAAGGATCAGTGCCAAGCTCGTCGCCTAAGTCAAATGACTTTAGATCGGCGCCGTAACTATGGCCACCAGCTCCTTTATTACCGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +%##%%%&0//14<>N9;5GIDI>>@A@0IPIGJ>?''=6<69?<>35CCAFJH@<.--66875-56$*DC=<=?AA==9PG;?AFFEB>?;42<:=::JD=??AH6?=A><9,912.2,2&,=AA<368;:5666E=6=,-2374-44EDDGIBICA=A@64)):=@=98,(($&%+02<6(G;=KHB=?=9ACD:=,./(9:7E?A@>:A==CD@A8;//--C.3=6:A;@D>?A>76349=BMD349>?B<@CFE@D:JFC*/62/2(*+6HF@IBBC:HE9:A@?8955?A@72&-<9<==><@@??=>9623-.(89:<94=6CCK@B99:;11?488<892),2732569:812=>9?>D;111)87=-.7?AAC=6@=<:@:<=GEL@;886<;=?=ABB>HH?>B=433110-,-/&&() +@SRR11410539.607606 607606/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAACAGACGGCAACGGAATCGACAGCACCTTGATTTGAGTGTTGTCAATGCCAGATGCGTGCTAAGCACTATGTGTGTACATTGGCGACCCTGCTCAATTACCTGCACCACGCACATTGCCCCAACTAGGGCACACTAGAACCAGAATATTTCAATTCAGTGTGTAGACTTATGAAAACTATAGGTCAGACATGTTCCTCGGAGACTTGTCGGCGTTGTCCTGCTGAAATTGTTGACACTGTGAGTGCTTTGGTTTATGATAATAAGCAAAGCACATAAAGACAAATCAGCTCAATGCTTTAAAAAATGTTTTATAAGGGTGTTATCGCATGATGTTTCATCTGCAATTAACAGGCCACAAATAGGCGTGGTAAGAGAATTCCTTACACGTAACCCTGCTTGGAGAAAAGAGGTGCTGTCGATTCCGTTTGTAGTCAAGTCTGTTTAACATAGCAATAAC ++ +%$'('&&./+,).6/):BB<;75343,29$%).*0(()&-'0%&***+*/)79=EKD?JHC>CIKJFHKF@?HIEBLB?B@D;DKNFG@ACF>=&::=7;>(()57>@BC=DA<786%%%)%%%%.A>>;:=B>:?8:<10&&&114,4*;59?'6<>E>F;,9<>4@?CHF7A@A>2>9@@?FDD>B=565.,*/00.5<<5>?.%,');>A:4@=,5%>BGF59A57648<(44:@>=@@>JIDF3@B>8:735*3..8DB>JJF;=BA:=@?A?0.(%%&%9:++<>A44@B02337996:73A6<,-))%%*(+,3375&(7:;870*+()4@=EA1-*.15?@?ED@BD@?A@G@@FCGE987,,+,+76@A=?=?/445)0512/*34;/HDFFE@4B@@BCD@>/140146;/$0&7=>=DBD>@;93=:<ADHG7?:())-)/4*:91:86/)'@8:;@@II:.BAB:IF57.8++$%982,,86<8B=:4*+,,',,888+,.557?DB7@1)$$':;8E@9;29//.@D>>=FA;958<4>@EEA:-,05666:640>6.+34BA@92512DFFA5-&)05+,2..024;>?D(,9:C<72A,9>@A=:3C>:32521.::C>=;?4656>?EGB75%%7<@4.+,-)39;.0,=33/+1==500?=?B>@>/&'5<9AC7*,89A??AE@.(&())+--+++.&)'-35&2;@455?<=>86@DA**>?9BBA1+/,18777111.4.5>5251=79%%$$&'(',0/.7<4?@827?:22:;;.,'%&/1*%&0,;=<9%%$'#24(+,)&),2<22D@@=760,'7;(73;?@*,$$41%%%(*-9800+&/4;42,12$$1&&$(&& +@SRR11410539.1475444 1475444/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACTACAGTCAGCTTATGTGTCCGGCCTATACTGTTACTAGATCAGGCATTAGTGTCTGATGTTGGTGATAGTGCGGAAGTTGCAGTTAAAATGTTTGATGCACTTACGTTAATACGTTTTCATCAACTTTTAACGTACCAATGGAAAAACTCAAAACGCTAGTTGCGACATGAGGAAACTGAACTTGCAAAGAATGTGTCCTTAGACAATGTATCTACTTTTATTTCAGCAGCTCGGCAAGGGTTTGTTGATTCAGATGTACAGAAACTAAAGATGTTGTTGAATGTCTTAAATTGTCACATCAATCTGACATGTTTGAGATTTACTGGCGATAGTTGTAACCCAGCATATGCTCACCTAACAAAGTTGAAAGCATGACACCCCGTGACGAATTGCTTGTATTAGGTGCTGTCGATTCCGTTTAGTCGTCTGTTTAACCTTATAGCAATACGCGTAACT ++ +&$$$$&'12A?@GB512@@C<=99//..:9:/@DACFG<=:>=A>ADF@BD>>78@>6:=BB>>=30+)'%'34/?9:1>?=911-)%'',#&>=6=>B==?BBA?996.&<C:4-('+*/<<98=>*&-&**,,00314,25<@?;=:1.%++,(55)&%$$%%%$(*)2%0/10==?D;BIH,57D11?889A?A9?8423))8;89043332/;@A127/;6DEAC*2=016:BCHH=>77643-)*%$#'"#$$('&&(33-)#63<-,),**1*.496652//30*B/=?;=9,%9%&&(#$#$%$'$*&$%&'(:9>E>B>A??B3831+,'-%4&/61111=>:10:<=??84DFBBF;$*7ADG?BDED<5B<..&%*+0-%%%7?D?=543A@?D2,@A;<;037:6,',999=B=FABC785832'$(%&$%%'$#'&&(($% +@SRR11410539.2243895 2243895/1 +TGATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACAGTATTCTTTGCTATAGTAGTCGGCATAGATGCTTTAATTCTAAATTTGTACTTCTAGTAAAAGTACACAATTGTAGCAATAAAGTAAAGAAATGGAAGCATATAATTAGTACAAACACGGTTTAAACACCGTGTAACTATGTTAGTAGTTGTACTAACAACTTTGTTAAGAAAAGGCTTAGCATAATTAGCTATAGTATCCCAAGGGACACTATTAACAGCAGCTAAACCATGAGTATGAGGGTTTTCAAACCCTAATACTCTAGATAGTTTGATAGGTTTCTTAATAGTAAGACTAGAATTGTCTACATAAGCAGCCATTAGATCTGTGTGGCCAATATCTTCTGTAATTTTTAAACTATGCTGGTTTAAGTATAATGTCTCCTACAACTTCGGTAGTAGGTGCTGTCGATTCCGTTTGTAGTCATCTGTTTAACCTTAGCAATACGTAAC ++ +#%(),./78@CB31;+720017(+;>B;::=9))(+(*24459==@<<;:AB>=>=;<=D=;?69G>82210)&''(6898<.&*?BFJ?97<>?09<6?EKA7-89DFD<<:?/6303AC=>?,*459%39883./-$.1AAB@=@<=9:B?AHJF?=9;==?GADB=?9:?E@G@@>A:%%26./<;=AB1+4901*650%)%$$%357BB?A@91,22/@?EEB55<702&2@D:C>9=238;4=/-8&.2.62E:99))8;<5007?>CBR7:@B<@=0=A7/++,>9(;%$&%%%4-=:7<;7<::<;D==@:4++297:51242..1986BDCE62//0;9?<+*%%34;>A>CCEIBC?77.);;;A@CE:57;FCD35394:0=>?><=><=>?>=?574489AA?70$ +@SRR11410539.609595 609595/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTTCTAAACGGAATCCGACAGCACCTTGTTTATCACCGCGAAGAAGCTATAAGACATGTACGTGCATGGATTGGCTTCGATGTCGAGAGTGTCATGCTACTAGAGAAGCTGTTGGTACCAATTTACCTTACAGCTAGGTTTTCTACAGGTGTTAACCTGGTTGCTGTACCTACAGGTTATGTTGATACACCCTAATAATACAGATTTTTCCAGAGTTAGTGCTAAACCACCGCCTGGAGATCAATTTAAACACCTCATACCACTTATGTACAAAGGACTTCCTTGGAATGTAGTGCGTATAAGATTGTACAAATGTTAAGTGACACCTTAAAAATCTCTCCTGACAGAGTCGTATTTGTCTTATGAAAGCATGGCTTTGAGTTGACATCTATGAAGTATTTTGTGAAAATAGGACCTGAGCGCACCTGTTGTCTATGTGATAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACTTTA ++ +(%$%*.-@AK170:ADF?>;933,8:==0DPHINE=//51,)%.($%12+(())+''85;@A@CC?@CHAABA/*5-+49;%%*9>:3=<6;ACDB0<;?@B@;G@G@@4815@)0<>>@1151-0-,%&(@?<=)-62.:25169--.-4322<:847448835;>F;<>@C><=>AD>>7BD;?AA9?FCCCFI>A:@=<>A?F<0@&74;/2/5HELDA?BC4?2A?=?<=AHCAEEJB<=$9DF:SK:;ADEI@@BC=@C??AC:,-.CA<=9%*%'258?@8:?1=%(DEA@J@>F9:8;6::H:=?::3./.0&$,,B?=8CEEBBDA??A=B@CB4:9=-?AD?@C?CBFJH;=>MIH88<7<=:7>>=EFD@@::73,<;@ACK@;80.##&&$ +@SRR11410539.95343 95343/1 +TATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAGCAGACGACTACAAACGGAATCGACAGCACCTTGCTTGACGTACAAAAACTGCCATATTGCAACAAAGATTGCTGCATTCAGTTGAATCACCACAAATGTACATTGCAAATCTACTGATGTCTTGGTCATAGACACTGGTAGAATTTCTGTGGTAACACTAATAGTAAAATTTGTGGGTATGGCAATAGAGTTATTAGAGTAAGCAACTGAATTTTCTGCACCAAGTGACATAGTGTAGGCAATGATGGATTGACTAGCTACACTACGTGCCCGCCGAGGAGAAGGAGTAGTCTGAGTCTGATAACTAGCGCATATACCTGCACCAATGGGTATGTCACACTCATAGCGGTTGTTGACATGTTCAGCCTATTAAACAACCTGCGTGTTTGAAAAGCAGTAGAACCTGTAGAATAAACACGCCAAGTAGGAGTAAGTTGAGGTGCTGTCGATTCCGTTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +))*+8;<78;89?;@E>;9<97/169?I::=4485;<;13>=>=FE7B9-,<;?A808=A)<@@CBA<31-:<;>>BCH??4E09,'&&$$&;:?9<3:/<=EB@?@67<@:8:@@AA?::?@==6;979882-+0(,',>D@5:?;9=:?D<73885=<=>?A55&'-%/0+;FE<<52,,**%'&$)264GA>AB6A46JDIMF:=>1:9455;F:7,8>>ABEBA627764.,%)1258,.&$'C<1/98;933=;>A?>?B)/).F@CAB;<=@A60$( +@SRR11410539.1119342 1119342/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACGAATTTGACTACAAACGGAATCGACAGCACCTCTTTTCTCCAAGCAGGGTTACGTGTAAAAAGAATTCTTACCACGCCTATTTGTGGCCTGTTAATTGCAGATGAAACATCATGCATTAACACCTATAAAAACAATTTTTAAAGCATTGAGCTGATTTGTCTTTATTGCTTTTCACTAAGCTTATTATCATAAACCAAAGCACTCACAGTGTCAACAATTTCAACAGGACAACGCCGACAAGTTCCGAGGAACATGTCGGACCCTACTCATAAGTCTACACACTTGAATTGAAATATTCTGGTTCTAGTGTGCCCTTAGTTAACAATGTGCGTGGTGCAGGTAGTGAGGTCGCCAATGTACACATAGTGCTTAGCACGTAATCTGGCATTGACAACACTCAAAATCGTTCAGATTCCTTCGTGTCTGTTTAACCA ++ +#$*++4.<=?;8K87'&=@;9AIMKJBBC;;(FIIEF?/%$$#&'9.9>B@;<64-0.799=A:1@BAAB?:?DOFBB*9/0)(&5=A:=:2-;50.0-(&$0.3*)567;6(49>??2876+800.0)+*0;?7:>B?@<688@F;=;<872*'$$'%%$,($&(9;51*2%1+132-,.**,&&+2-.((.-06GA;@C>A850;;6/5DCD@>2.;<2+@./<-0-.?C12-+15?855<@?<=F>78:B@%,20)*0+2<>5,+*.85421--)**669=<:4,%')&&(*4/38<>BCAAA>=@8262%,'-0=2;(+1114088=..3)+$&23:H;1(.'0686C@>A?>F@@9EHFIK35:8:7>=?<-;@@6,&(%/4583BC<65??B>?(0.BCCB6.+)765*+16C5<=338=:>9>,GGPH=@AA?=F65;8?AC?<0-3*)1;<9?A=689::410%588998C>=A::4.-%')67:?:<>B%%5216BCJIF;2?ECB>>2EH;)&%('%$*9018;9?543+6676775%);:=>CFAD??77:>;=EAAGLF38A;639:;A7778;=>?:&,0558>>***>?:;>B@GF:;:BBHDOJCABADB@<4/)1B/09=@=BEB>BCAB?AC?HFK<1;/8964:>C@@?;<<988&*BDF==8/$, +@SRR11410539.107949 107949/1 +GTTGTACTTCGATTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACTAAACAAATCGACAGCACCTAGCACATCACTACGCAACTTTAGATACATTTCTTTATTTAACAAAAGGTGCACAGCGCAGCATTTAAAGTACTAAAGGAAACACCATTAAAGACTACACGTCTCTTTAGGTAATTACTAAAGAACCAATAAATGCTTTGTGGAAATACAAATGATATAAGCAATTGTTATCCAGAAAGGTACTAGGTGTGAACATAACCATCCACTGAATATGTGTAAAAAGAAACATCATTAGTAAGATAAAATGTCAAGTACAAGTAAATAACAGAATAAACACCAGGTAAGAATGAGTAAACTGGTGTTAAACGAATACAATTGAATGACATAAGGAATAGTAGAAAAACATTAAAGGCAGCTTCATGACTGTATTCACCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTACTTAATACATAACT ++ +.019==:;;.)'8.4.7,.)*%/%022,400*;A=AEJ@D?@==88'&&&23'-$&''1000--*5:;;@67>?F>B1DCBA//87-../$%*$$;=AADCMLC9BA:01278-''=D750/0-/-)'$$%'('01,(2..155%')%')$546=BA>@57>3''.4595:B>CCH89;A2753/%)/+$%13;-=123571/A6.3602&&)>989><740=57357544,/.2=8332:6;H=69401032?>>'(*BB24/('&(&54117(66(*(,%&*010%'%)33;;;;9''*,12/0.-+()$,,*(&$%$&))(',('##$&)/482=B=<66@G43:=>5<<21>69??EFA686=97500=7999+)(%&%('$$$8950.%'$'"# +@SRR11410539.2225744 2225744/1 +CGGTGCTGCTTCGTTCGGTTACGGCCCGCTAAGTTCAGCAGACGACTACAAACGGAATCGACAGCACCTACACAGACCATTCCGACAGCGATGACAATATTGGCACGGCGCGCAGTAAGTGACAACAGATGTTTCGTCTGTTGAAGCAAGGTTACTATAGCAGAGATATTACTAGTATTATGAGGACTTTTAAGTTTCCATTTGGAATCTTGATTACATCATAAACCTCATAATTAAAGAAATTTATCTAAGTCACTAACTGAGAATAAATATTTTCTCCAATTAGATGAAGAACAACAAATGAGATTGATTAAGCGAACGCAGTATTGCTTTTCTGTAGCGCAGTAACGCTCGCTGCTTGCTGACTTTATCACTACCAAGAGTGTGTTAGAGTACAACAGTCACTTTAAAGAACCTTGCTCTTCTGGAACATACGAGGCA ++ +'$'0%"*$')+12=0<%*57/3&'+++%$('(+6-((%/++*%=A=@8ACEE=3:-4<==HCHDECIG7---/''434*,1%)'%%&%)'%41&6;5++:8+(('&(.2*&'*%.89=>B=;)''537<66BA1*$$&%%+.+'&#(%&/6::14542/2,0('*($#$)-%46-6//2>@7;=CG=OJC=5645:I69@ACI@A8=67/-'&(39<95-)*13(/-3?@?DFD<55($(.6<@G>7A9C:6<=<(:759<5487:2',%@;<<3%%+6677-.&.$$$+,*..+&(AB??@B23',,*12()&$(&-5%&&&'(%&%($%$#%&$'%%$#%')*,5'''(%#$*(28:1'**&+034600/(4735=A6/-')&%&&'(%%%#$%&''$)$/*%:;:??GLCLC>(-1**08770-)+.-# +@SRR11410539.1312277 1312277/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACGAAGACGACTACAAACGGAATCGACAGCACCTTTGCCTTGGTGATATTGCTGCTAGAGACCTCATTGTGCACCAAAGTTTAACGGCCTTACTGTTTTTGCCACCTTTGCTCACAGATGAAATGATTGCTCAATACACTTCTGCACTGTTAGCGGGTACAATCACTTCTGGTTGGACCTTTGGTGCAGAGTGCTACACAAATACCATTTGCTATGCAAATGGCTTATAGGTTTAATGGTATTTGGAGTTACACAGAATGTTCTCTATGAGAACCAAAAATTGATTACCAACCAATTTAATAGTGCTATTGGCAAAATTCAAGACTCACTTTCTTCCACAGCAAGTGCACTTGGAAAACTTCAAGATGTGGTCAACCAAAAATGCAAGCTTTAAAGCACGCTTGTTAAACAACTTAGCTCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAACCATCAAC ++ +$&#$)--:;=<>C//(;?CECECBDC87***3BPI??4+&&*./>BD==B:=;@=>?D9B6DG9;BA>6)))0*02871+%*=>?:969/.-A?@F4--1892+)'*)+3/@CI??=*0FEHJC?@C:9=;1)4+))&-9<449>=92352,-?EA><@D@ACB=>634:89<>??9-,EABBA?@;>?B@>=9<-08:8'+.27+,:59=76=B20.$$$$&,=A@;=@BAM>E@>520,--9473;==00,,%*0//8),+/-/725'?FF?=<>*BE?@MJ<:?>@<<=4-62();>FCEHF?@7>>>;GC789@A>D>(>A@>B@B=?>@ABAH=9951E-B;34JHA?=@@=@%+;;9:,>%(.9:312.6934/844%,+*',662@AA:/0(%,+.('DDDJGGMHHBE>>11,:)@45+963)/87:,,:;9;6;:;=ACA;>93?;A><580-.+,-)*))%(((*(() +@SRR11410539.1199462 1199462/1 +GATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTAGATTACCAGAAGCAGCGTGCATAGCAGGGTCAGCAGCATACACAAGTAATTCCTTAAACTAAGTCTAGAGCTATGTGGTTTACATCCTGATTATGTACAACACCTAGCTCTCTGAAGTGGTATCAGTTGAGCTACAGTAGGACACCATCAACAAATATTTTCTCCACTAGTGGTCCAAAACTTGTAAGTGGAACCTGTAGAAAATCAAACGTGGTTACTGTGCAGAATGCATCTGTCATCCAAACAGTTAACACAATTTGGGTGGTATGTCTGATCCCAATATTTAAAATAATAACGGTCAAAGAAGTTTTAACCTCTCTTCCGTGAAGTCATATTTTAACAAATCCCACTTAATGTAAGGCTTTGTTAAGTCAGTGTCAACAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +&$-&$$.4569<6(%+/594,4,67:;A;;1JKIFH575<5;3/55178:1:696488><72565643943100'8;;:9=56/874CDF<<:74931<639+54@BDBF@@(@@=DAA@>9:;=?A235@B;998<7/2<7.$$-%)(-;=?A$$*.43AB902;5@41..0.8<2DF:A=.&&%,/$%&(&)(-%+*)%,-&%+%%%(+)('+-2)?:;=EFC?ALJNC:6$&$#0539(),)+5773@CD9:*+2A583%%'&(.*)3&/*&&&('%'2'-4/%%$$&(7;<8F<=D>;C;:9:8--:<=2?>A?>=99@;=?>CL<@;1&'&;=6/A)))8C;@<=((*&99:CC897991,:;<7IID>AFC98?@FGA@967/4CHGI?>C8:536/:F92?:;<87()958=>;?@EJC:;;FBB@GFEA?AFEF<760)((42..;;:8/$( +@SRR11410539.1713237 1713237/1 +CAAATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCAGAATCGACAGCACCTGAACAAAGACCATTGAGTACTCTGGACTAAAACTAAAGTGAAGTCAAAAATTGTGAGTAACAACCAGTGGTGTGTACCCTTGATTGTTCTTTTCTGCACTTTGGAAAGTTAACACCTGAGCATTGTCTAACAACATCAAAAGGTGTAAATTCATCTTCTAATAAGCACTACCCAATATGGTACGTCCATTCATACCATTTTGCAGTAATTCTTTTAATGAAGCACACCTCTAAAACGGCAATTCCAGTTTGAGCAGAAAGAGGTCTAGTATGTCAACATGGTCTTGTGTTAGAGGTTCATAATTGTACTTCATAGCCACAAAGGTTAAGAGTCATTAAGAGTTGTGGTAAATCGATTGGCTACCTGTCTCCATTTATAACAGCAGCGTACAACCAAGCTAAAGAGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACTT ++ +.&&$$&,074459:@12,55832200/19;A776DA=-/0+$('365=>44;4$+(/,;62.?:A4=DH>E@::89?A=120)(*98;;?9BEGA?@C?9$,:<6.?@A?95FIJADECH=3/19<>:;34CCB@?45>@DE=:DB?>?ADSHAD<3;;;.'.8:>>DDC=?;=/)%,69:7@@@<;06---<59<..800?,&6FH-%+:9:.,/23*5-=8A.;,@B@??04,'(&&//**3;87:52:<>>@A;837B;=;>?TMJD@BBE@.?B<53%(&&%15B<8;24*/&*39FDD=6;4=>.*$4+%?(9+@@AA:?79?>@<>8:EGBECA<>33=;C9901307;;;-@AA<;=ME9:0:9DE(7*;==>>?<8A1124=ANHJ@5>/-<:>A?@69===;@=93/06687C?;,,%%( +@SRR11410539.589692 589692/1 +CAGTAGTAGCTACGTTCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAACCAAAAACTTGTCCATTAGCACACAATGGAAAACTAATGGGTGGTTTATGTGATTTACAATAATAGCTCATACCTCCTAAGTAAAGTTGAGTCCCTCTGTGACATCACAACCTGGGCATTGCAAACATACGGATTAACAGACAAGACTAATTTATGTGATGTTGATATGACATGGTCGTAACAGCATTTACAACATAAGAGAATGGTCTACGTATGCAAGCACCACATCTTAATGAAGTCTGTGAATTGCAAAGAACACAAGCCCCAACAGCCTGTAAGACTGTATGCGAGATGTGTATAGCCTCATAAAACTCAGGTTCCCAATACCTTGAAGTGTTATCATTAGTAAGCATAACAGAATACATGTCTAACGCCTTGTCCTGTTAACTCAAGGTGCTGTCGATTCCGTTTGTGATCGTCTGTTTAACCTTAGCAATACGTAAC ++ +'#&%$(,-/2448:C3<&.=?@>=>ADE>>9;:6@IH=?1:685576@A=7:92,357:87?B@B?DEC1@JKCAKNE@:BIJ@?AA6575459:EIDDB=?/79773*+-**4=6?@?@GEC>?<<89;3;.<4>=@;79>*-;;<=;6743A:<1978?=99<34=7<<:::A33<;?2+1'89BDHGGLFGE@A>=9E?EG?CAB;<;=GI<=@?CD@CEECA@BC;:9@>@;;33;;7857:<97??::*99/081%6@:;==>@8;8@>57>78:G@@@?@C>?J?AFC>B8635759;;:AG8>?@&0+AAC:=8:5&%%(*2$0&9/0/*5?B8:;>><:@CHC@4=;=D@A@9:.(4)$%%%##&-244>A?A@56:8@561=>>BBC?8;4=)/66442'&#%" +@SRR11410539.2193694 2193694/1 +GTTGTACTTCCCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTACCACTAGTAGATACACAAACACCAGCTTCTGATCTTTCACAAGTGCCGTGCCTACAGTACTCAGAATCAAAAGTTATTTACCACTCTAACAGAACCTTCAAGGTAGGTGTTAGGAAATTGAATAATAGAGCCATCCATGAGCACATAACGTGTGTCAGGGCGTAAACTTTCATAAGCAACAGAACCTTCTAGTACATTGGTATCATAACAATATGGTACTGGCTTACCAGAAGCATCTTTAAAATTGTACATTCAATAAAACACAAGCTGATGTTGCAAGATCAGTGTACTCTATAAGTTTTGATGGTGTGTAACAGATGTTACCAACTGCACTAAAAACTCTAGGTAAGAAGTAAAAGTCACCATTAGTTGTGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTATATCAT ++ +(/0856===')66A0<4?C=7AD;932/**.*+/457967:::<4//4/,)+.0:?8A88953>:960@9?>?C7>5@@9><<97>78@A:69:3+?FD><>66:>90-+9ADK>?H7>=>EDCF?>CACD;=8+/33<<E;7?:=<;==86333.$-*,:;@?B<2,&99307?>BFH@ADF;6==@@E@>>>27G200*)12<=>@C=07:@1==1/056*&=7;<:)(#58>@A??BDE@?@;<;68/7--+,'7*.;<>CHG>DF?5667AIAA>>687;>>;1/081<5)@6+7544CCA?6%*JQMJ=?:A;-.$%$6>AB7.5I)$)/1()%$$(&(/'+%' +@SRR11410539.1550900 1550900/1 +CAATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAAGGCGACTAAACGGAATCGACAGCACCTTGTTAAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTGTAGAAAGGTTCAACACATGGTTGTTAAAGCTGCATTGATAGCAGACAAAATTCCCAGTTCTTCACGACATTGGTAACCCTAAAGCTATTAAGTGTGTACCTCAAGCTGATGTAGAATGGAAGTTCTATGATGCACAGCCTTGGCAAGTGACAAAGCTTATAAAATAGAAGAATTATTCTATTCTTATGCCACACATTCTGACAAATTCACAGATGGTGTATGCCTATTTTGGAATTGCAATGTCGATAGATATCCTGCTAATTCCATTGTTTGTAGATTTGACACTAAGAGTGCTATCTAACCTTAACTTGCCTGGTTGTGATGGTGGCAGTTTGTAAAATTGCTGTCGATTCCGTTTGTAAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +$#%$%-449;<>BI=81>DBGCBCHDH>=>3),:DFDF=>-.,%,(())02.1353;>>;8423)8@337*..57CD861.+-47=>.+;=EDB3525@CCFDC9;%%<4<9=>*-++,6:EGBA>3:FEDGC-1@;:B33:FIIHFC<79,-(,$)&+((%0978A<=EDE<57::B=@B@4=@?=A@BBBB=:-/)<6854('&&(+;>>9::5*''':;@BGH2@19,6;;9@?C?ABDCAA;=>35>>C2=GKEAB:5888EA67AC<=69-@FAIAFB<>@??E9BACC<64679-<98)$8:CACDA@=D<@=BB@FEFC-?)7,<2/((567('%%'/%#$7:;>67,,375>AA?::A68.(518B64*+&('/4677>BCABFAD45022>?:66B>>@?FH=A>8:.5660/=:<<=3, +@SRR11410539.1781029 1781029/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACTACAGTCAGCTTATGTGTCAACCTATGCTGGTACTAAGATCAAGGCATTAGTGTCTGATGTTGGTGATAGTGCGGAAGTTGCAGTTAAAATGTTTGATGCTTACGTTAATACGTTTTCATCAACTTTTAACGGCCTGTAAAAACTCAAAACACTAGTTGCAACTGCAGGAAGCTGAACTTGCAAGAATGTGTCCTTAGACAATGTCTTATCTACTTTTATTTCAGCAGCTCGGCAAGGGTTTGTTGATTCAGATGTAGAAACTAAAGATGTTGTTGAATGTCTTAAATTGTCACATCAATCTGACATAGAAGTTACTGGCGATAGTTGTAATAACTATATGCTCACCTATAACAAAGTTGAAAACATGACACCCCAATGACCTTGGTGCTTGTATTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +(,-7=;9N9>:<@B=@?BB:9*/-$&$8DBDI>>?=FABJABGBEF48(.(==?<==@=C@@=>>;7*2,921'11122335)$9&(77><$$&('%/')/&&2156-.89745959;87<7>::1439;4>8732;258:68?<>4>:@:>FF8B>>GECB?;918BED=JE<B?D>F???ID:366(,,/887::;;=:))$%&)0;<&&-%+ACC?HI>C>?=@DAF@=;==@>:?A/;=8<8;D8:&,6)*39>DHG>>???G>A@<710C:;=B=EB,<<-1589AGKC::GIH=>BB=A>ECA8=9?=C:BE@F>EGEAA@<:B?2,665.02:<731<@BDAFCIBD=?>FF;/-9:9:@AA;>@5/''(((((1/,>A@A>B@A>@@DCD<69;765430'13:966;76/.$% +@SRR11410539.192227 192227/1 +TGTTGTACTTCGTTCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTCATTAATAAAGGAGCTGGTGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGAAGCTTAGGCGACGAGCTTGGCACTGATCCTTATGAAGATTTTCAAGAAAACTGGAACACTAAACATAGCAGTGGTGTTACCCGTGAACTCATGCGTGAGCTTAACGGGAGAGAGGGGCATACACTCGCTATGTCGATAACAACTTCTGTGGCCTGATGGCTACCCTCTTGAGTGCATTAAAGACCTTCTAGCACGTGCTGGTAAAGCTTCATGCACTTTGTCGAACAACTGGACTTTATTGACACTAAGAGGGGTGTATACTGCCGTGAACATGAGCATGAAATTGCTTGGTACACGGAACGTTCTGAAAGAGCTATGAATTGCAGACACCTTAGGTGCACACACAGCCGATTCCGGTTTGTAGTCGTCTGTTTAACCTTAGCAAACCACGTAAAC ++ +$%++*-+:?AB@K6:'-79>>7D?AF>?@660?OIFKH8B;AFBEBGEDDF7+%'+6>@=E9E2@F;:A5##$**+04.))'=C@@BC=<::-1,=.0+201@;=9@>GJ?,&2%#$&$'&$111;=FCEH?45)''&134238=>((2(*@>=<9*:@DL>>330>IBD<<:ADE@?A?FA;13565CGDBAC7>B=424++''''8;@04)*&,1%/2:>:545<8<<<,,>>;=57221$$,$$#&):;95;=;,(0.5+-+*0789;?B@B;DJEIIKDIH/8D?@B?B=?DBE=CHGDE?A2*-<=<;>?>CCACFI88JA??;@@:4;77*688HJIJ?BEGC?61,,.=FFIA899-234.6.>CFED9LE@;<0A=DA@;;8B@?;<>8>7971'0+4()*$&&$%%%#*204:(,$*&)3146531)7<=AC@2..-.,/0$$#$(&'1311*,&( +@SRR11410539.424988 424988/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAACAGGAATCGACAGCACCTATCACATAGACAACCAGGTGCGCTCAGGTCCTATTTTCACAAAATACTTCATAGATGTCAACTCAAAGCCATGTGCCCATAAGACAAATACGACTCTGTCAGAGATTTTTAAGTGTGTCACTTAACATTTGTACAATCTTTATACCTTTTCCCATTCCAAGGAAGTCCTTTGTACATAAGTGGTATGAGGTGTTTAAATTGATCTCCAGGCGGTGGTTTAGCACTAACTCTGGAAAAATCTGTATTATTAGGTGTATCAACATAACCTGTAGGTACAGCAACTAGGTTAACACCTGTAGAAAAACCTAGCTGTAAAGGTAAATTGGTACCAACAGTTTCTCTAGTAGCATGACACCCCTCGACATCGAAGCCAACGTCAATACACGTACATGTCTTATAGCTTCTTCGCGGGTGATAAACAAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATATATTTT ++ +-***+)452,&6*80453)+)-.:@;ACCC(5;IIIL=?9:?@BA=<=9;9/'$..)6667..1004::2+3==?2/2-24*+$30;/B<<;F;:4>733/+4>;58*,,?A?E<=BGF@5498B4+'A:;=5,9;=3CBE>@=?CCC???ACD?FGE?=<:CAD=>:616(/86CCBA7577HE8B9A<))+BBD?CBG=;F=FG=?JI@70/&+&../$)7:>?&.+)/;34@<>B?EIC@EB=?=?@E=?BC=5285;;=B8,/47;A@=C@$@9AAE>??@=9BFFB>:<::B=6/.@>09634/'52*44AA/)65)),,/11+5((210+)*29,47)'-//25(/7145>:?<>AAB?852)./$$$$'('%0-,*+)5=DHGD>A?9?81'&%),,2BMIE=>=>@>CDADE@>>>$6=DCCC?:844;A7;><::42126-0--.'##%%%% +@SRR11410539.1493037 1493037/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAGACAACCAGCACCTACTAGCACTCTCCAGGGGTGTTCACTTTGTTTGCAACTTGCTGTTGTTGTTTGTAACAGTTTACTCTCACACCTTTTGCTCGTTGCTGCTGGCCTTGAAGCCCCTTTTCTCTATCTTTATGCTTTAGTCTACTTCTTGCAGAGTATAACTTTGTAAGAATAATAATGAGCTTTGGCTTTGCTGGAAATGCCGTTCCAAAACCCATTACTTTATGATCACCAACTATTTTCTTTGCTGGCATACTAATTGTTACGACTATTGTATACCTTACAATAGTGTAACTTCTTCAAGTGTCATTACTTCAGGTGATGGCACAACAAGTCCTATTTCTGAACATGACTGCCAGAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAATACATGCT ++ +++-$$$4579;B+-&06;=;8<8-0(7;?@)989885+&*&(6;?DFDBC97%*%+)+,-/47483CCBDF@HAB:599?$410;@>C@H9<../1?;::?,622=>EA@D<;9.,//13C12<:;<:II;<:5%/A;2C:>B?;GHA@IBBA789998741::8<:9CH=73;8?<@ED7?@BD51-,-+>@;010;=F@A9;9DA:%,%%%'+$(89:<2;DKKLA??,-@C@?@<<8<:-7DEA9@?8<=>7966BB850%%#+3%%523*,H<;HHG?>A463)(--/&'&)'$*%/361:78::8;33@CA@6@==2''-')''',1-1/,%('/&13((+-,-535385;;A=<839%%7**)00292441;8?;:2*+.(22(=8B0A<*3B?B><7?CDA?-06<=72/0-1407<11=<2**&*$$23221$$#"$ +@SRR11410539.103412 103412/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGGAATCGACAGCACCTAATTTGGAAGAAGCTTAAGGTATGTAGAATCTCTCAAAGTGCCGGCTACCCAGTTTCTGTTTCTTCACCTGATACTGTTACAGCATTATAATGGTTATCTTACTTCTTCTTCTAAAACACCTGAAGACATTTTATTGAAACCATCTCACTTGCTGGTTCCTATAAAGATTGGTCCTATTCTGGACAATCTACACAACTAGGTATGAAAATTTCTTAAGAGGTGATAAAAGTGTATATTACACTAGTAATCCTACCACATTCCACCTAGATGGTGAAGTTATCACCTTTGACAATCTTAAAAGACACTTCTTTCTTTGAGAGAAGTGAGGACTATTAGAGTGTTTACAACAGTAGACAACATTAACATAC ++ +$*+-;:=?@99I5;79=>?C?=;465')&.)46:D;DIECCAB>>D&(?D31>GH?;D<<3%)',*&=53<;E?B@>@6-.4:A<.@>:,?BHHEC@9111,4<=;?@D-$$'7%1@7/?AB>5//=:66E79@?%&8@=CG9999@9:'')C=<:@>;=;17897:CD;>01;1=,.32,%'&'*37?===*+5(36B@@:GJ>45FCCDBA;604@@;;278:77;><;=?AA@A67>=@88>A?<=HGFBEE:5;<3/=57024%'$))&&020..379B;:=>09DEA4?:>DE;;<<>BB=>44=?:83&19:@9:<201+&(->?<1-*+,&#$$*$%&+0**99>AENK;>6<:*+*679753;=5--14.*::AG5.7&'&&%%$$%#$%'1%62=99/$%%%,((.+)&,3'')-**/)$+'?78:9%&.<=CC>=@?<))5(6(&%+&)'//'.345=9>A44334/0(GHF=>.(:;+27/0:6DAB<;*($$245.-%%%+&+,1-/5<<>E9=777/.8<=8758+A:48.348-;;=B>BBC/1>D::;73C>B?@<;:,(('$%$%###+())(##$ +@SRR11410539.1987503 1987503/1 +CAGTAATGCTTCGTTCAGTTACACAAGGTTAAACAGACGACTACAAGCGAATCGACAGCGCACCTTGGTGAACAGTCATGTAGTTGCCTTTAATACTTTTACTATTTCACTTATGTCATTCACTGTACTCTGTTTATTTCAGTTTACTCATTCTTACCTGGTGTTTATTCTGTTATTTACTTGTACTGACATTTTATCTTACTAATGATGTTTCTTTTTAGCACATATTCAGTGGATGGTTATGTTCACACCTTTAGTACCTTTCTGGATAACAATTGCTTATATCATTTGTATTTCCACAAAGCGTTTTCATTGTTCTTTAGTATTACCTAAGAGACGTGTAGTCTTCCAATGGTGTTTCCTTTAGTACTTGAAGAAACACTGTGTTTACCTTTTTATTAGAAATAAAAATGTATCTAAAGTTGCGTAGTGATGTGCTAGGTGTTTGTCGATTCCAGTTTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +-&*(%%(&01475HD/&)412025000?CA>>,=<=>>A94-*+,-*-%$(.2540%2&4>8899-9''%#(.09;<:5?=,2456>:<@8955?A<-,-''((7'%),;11/3599<33.($$$:;>:>9-)$&%)'5-0706;5;;:=<5>@AF;>?EDF=FE@>;65*57;=73632.(&3;>@B<=JEA=@@:62/4899;I@GDB8;76@8:;=C@FDEDDB48=;BC=CB;@>C6C;66?/2/.::.),&))+-%%*,'&)&,/,0(-)*-4773*,%0;>>?6)?58B:7<;56''-=>GF:>9@>44-2''+/,0.-+,+1974.20%'$'$)+&3990*=2?>;:0.' +@SRR11410539.1032430 1032430/1 +CAATGTACTTCGTTCAATTGACGTTCGCTAAGTTCAAACAGACGACTACAACGGAATCGACAGCACACTCAGCAACTGTTTGTGGACCTAAAAGAAAGTCTGCCTAATTTGGTTAAAAACTCAGAATGTGTATTAATTATTTTCAATGGTTTAACGAGCACAGGTGTTCTTACTGAGTCTAACAAAAAGTTTCTGCTTTCCCAACAATTTGTAGAACATTGCCTGACACTACTGATCAACATCTTGATCCACAGACACTTGAGATTCTTGACATTTACACCCTTGTTCTTTAATTTAGTGTCAATTATATTTTCAGGAACAAATGCACTAGCAGGTTGCTGTTCTTTATCGGGGTGTTAGCTGCACAGGGGGTCCTAGCTATTCGGCGGATCAACTTACTCCACCCAGCGTATTTATTCATACGGGTTCTAAAAGCAAACAGGCATTGCAGGCTGTTTAATAGGGGCTGAGGTGCAATGCGATTTCGTTTTTGTAGTCGTCTGTTTAACCCAGCGCAATACATAAC ++ ++%&##%(*-209C=7%&%%%$,(.-$#$)'''(-%&++32438++)'%%)).,//4982.&$++*-'$(,$*+''&03243'%489.-+@C:'$&&$)%11'(%%366=6*+6<,,*-3685...=$$)%$$%)%%+.&%&%*(8;B;=DG>113(('%#$%+-C:E=@@=330212,<,::8==61/5??<89*$&'*,..''46646*(%14+--.,0%0&2356588:;4++%$''%%(&(.;<78A12117-477;;89@ED?PB?::<:;?:=10/%&(29:650+,-*..)(@727$'#)+()'('&+%1=9B>:;8''(00*("%$%6;;&'939959?=73<%*6/.0*+'(()&%%$(&*((/..1*'$*51><4$()%'&22**++('(3/*&'''./&)0-:;:::7(&%%4%.>61*$()(($$%'&*,%*2001<97@>;@DGG@56737:BB@87-*4C<<55+)77357$($+-,(('%,.9;:669:;<1&&$(&&#$$'01,('$&''' +@SRR11410539.49493 49493/1 +CGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCTGTTTTACAGGTTCGCGACAGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGATATTATCAGAGGCACGTCAACATCTTAAATTGGCACTTGGCGGGCTTAGTAGAAGTTGAAAAAAAGGCGTTTTGCCTCAACTAGACAGCCCTATGTGTTCATCAAACGCGTTCGGATGTGAACTGCACCTCGTGGTCATATTCATGGTTGAGCTGGTAGCAGAACTCGAAGGCATTCAGTACGGTCGTAGTGGGAGACACTTGGTGTCTTGTCCCTCATGTGGGCGAAATACCAGTGGCTTACCGCAAGGTTCTTCTTCGTAAGAACGGTAATAAAGGAGCTGGTGGCCATAGTTGCGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGATCCTGCGGG ++ +$%%%%%'$$%/$#(&(./,20/4?>:BBD<=C?CD?@H>=*BEIFF>5,/%(&'22;9+*/)72B4<>?BA98<5;>=3=A>77,2'+$%$$..33/2(.0=9)?2/A45=2=CC<'(''./4==<==1-&,047799>:D;@6@B>78A=7.'%&28CJBBC@C@7&8:A);-.;3&$%&#%&'--4403%',/,7*$%()$5815+($&'6<;>97?AA??A:?9?@DHBA7<44546,.4+'70(77844>,&1*:9=>B?;8>;>7DCHB**>C<78:>@?(<63+AEA>JA6BBC>;74230:<11@BDFB8B42/-/33368?@@=55&&.&$%$&% +@SRR11410539.844846 844846/1 +CAGTATTACTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTAAACAGGAATCGACAGCACCTCATCCAGATTCTGCCACTCTTGTTAGTGACATTGACATCCCTTTCTTAAAGAAAGATGCTCCATATATAGTGGGTGATGTTGTTCAAGGGTGTTTTAACTGCTGTGGTTATACCTACTAAAAAGGCTGGTGGCACTACTGAAATGCTAGCGAAAGCTTTGAAAAGTGCCAACAGACAATTATATAACCACTTACCCGGGTCAGGAGGTTTAAATGGTTACACTGTAGAGAGGCAAAGACAGTGCTTAAAAAGTGTAAAAGTGCCTTTTACATTCTACCATCTATTATCTCTAATGAGAAGCAAGAAATTCTTGGAACTGTTTCTTGGAATTTGCGAGAATGCTTGCACATGCAGAAGAAACACGCAAATTAATGCCTGTCTGTGTGGAAACTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGGAACCTTAGCCATCCCGCTA ++ +(&(%%$'%-.-1:D/=7=DB;<;4001=@BEE(.FIHILB@<><7322'=>6*&,7,.779?5=3=?AAF93//BB@AFB?>4;=507:962+/7=BAB>==@=:9=((=((:B8F<,+%-/.'+)1%,88:668%A3E1A675;C?JE:?;;--:77:74+))/56:=9+;>;@?88DA>7?AGLH5'7@B;,/?;;;D@DB@;F45G;?BB@A>//:9LCDD973..)(9878$%5<9@<.0,3:7;?ADDG@:7223BCD1+7B8@CDF96II=@?==::@CCA:::::85.-903?<>A>.77692.2864$%37;ACCALG@BFB>DBEEKBKDCDH@?=@<1-.*,/.*').+549<..996=?:DIB@<;@@08:>?8930/+952.(DB<><2./+'%2.-3&'14$;:;6/3.175>CF<=?=+*%'/0-37:9,%6:BAB=877>-;*)5(*%$%,-$&(%*%''%,-/$%+)&&&.079:8;:>C=>B:<=8:;77=5ADDFF;>A>9%%)$,3,+A;C>@@A3=(@:::B>;55-/0)))0./9:7.>@DI7CCEJ@@9A>;:=??9:13$$&,)+&#%&&%6995PLJFG:85343&();<9:137/712,-.4..4544-0(00-(%+1&)'$)&'&%%&)&158=>>B>3.7,<>:<6<3>16/6.<(3-)+*&(,-:>?<5;2388:994<=10,(*&%%*&'.:@=:65,%#,94(*/.-6677>=9;485+'((,?@<7:/()()+8A@>B<;---,&%&$,*'*%')'.19>E<>3459572%%))(#$#%$'''$'#%%$%(%%( +@SRR11410539.2448953 2448953/1 +CATTGTACTTCGTTCCCCAGCGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGGAATTTGGTGCCACTTCTGCTAACTCTTCAACCTGAAGAAGAGCAGAAGAAAGATTGGTTAGATGATGATAGTCAACAAACTGTTGGTCAACAAGACGGCAGTGAGGACAATCAGACAACTACTATTCAAACAATTGTTGAGGTTCAACCTCAATTAGAGATGGAACTTACACCAGTTGTTCAGACTATTGAAGTGAATAGTTTTAGTGGTTATTTAAAACTTACTGACAATGTACAATGCGAACATTGTGGAAGAAACTAAAAGGTAAACCAACAGTGGTTGTTAATGCAGCCAATGTTTACCTTAAACATGGAGGAGGTGTTGCAGGAGCCTTAATACGGCTGTAATGCCATGCAAGT ++ +$%'(*(/++,',/2'(''$'-22203226000AIGJMD>56:<:7;:6875)5%)&'.<;D=CA8@CE8;C>@@,)<;8924:**87??@C;C66DHJCCEB??297<<>=CEF@9<7727;BDG@72,-0,,.=@<9/3-,*+-1E;=;I=?<33%9;>C..<=4>444449,,77;=8;5BC=89%<=MG=>??@B:=>@?7;@@7/;=..&$)$&%$%('.@//0,%-2+-..,$%'440&(0512*'(57,&0,%**+.17?A772;236>?;5**+*+78&,'**/2=2+*9>?25/1,,2%,(+%%&&$$#%$*'%&$$&$&+2%&&$%&, +@SRR11410539.2111921 2111921/1 +CATTGTACTTCCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTGAGGTTGCGCTGTGAGGACATAGTCACATGCAAGAAGACACACCATGAGGTGCTGACTGAGGAAGGACATAAGATAGTAGCCCTTTCCACAAAAATCAACTCTTTTGATTGTCCAAGTACACACTCTGACATTTTAGTAGCAGCAAGATTAAGCAGAAGCTCTGATTTCTGCAGCTCTAATTAATTGTTGAGTCACACATGTGTCTGCAAGCTTTGAAGTCTGCCTGTGATCAACCTATCAATTTGCACTTCAGCCTCAACTTTGTCAAGACGTGAAGGATATCATTTAAAACGCGAAATTGCACCAAAATTGGAGCTAAGTTGTTTAACAAGCGTGTTTAAACGTACATTTGGTTGACCACATCTTGAAGTTTTCCAAGTGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTGCTCTCCCCGTAACA ++ +%$&'$.(**/$%6<6>6?DAC;<@FAA:A=--1>BB;>;:::812'),%%68:1))055374?>@4<<*%#'-%'$'%'-(&'$')&$$%&)('$$2/+,-++*)90%3%?BCE??8=B@BBBFE;791)&+,'05>5;89A;4&&24/00..:EACE9A7BBADHEM<93A;A;B6@DDEA85-,$'&&)));<7?BBOKI@?=>EAD4?1EGJI6768<>14'82>;(6:1-/+096:02567A<@@@9;>3.?,,BBE=8<=@=@N@?,9:?.9'??;>+++<<=3)=/0/:817:69*AA5:>;)):?===22$$(*068A9?87>><;,,18:3:>)CDDACAFGB::=ED<>=?A564%'(*&&$1148:26/5@A>AC=:=?D:@5=?@>?B=?DFDCE<1+($%).;<;.$&&''' +@SRR11410539.261583 261583/1 +CATTGCCTTCGTTCAGTTGCATGCTAGATTAACGGGCGGCTACAAACAGAATCGACATAGCACTAGCAAATATTGGACTGAGACGGCCTTACTAAAGGACCTCCTTGAAATTTGCTCTCAACATACAATGCTAGTTAAACAGGAGTGATGATTATGTGTACCTTCTTACCCAGATCCATCAAGAATCCTAGGGAGCCGGCTGTTTTGTAGATGATATCGTAAAAACAGATGGTACACTTATGATGAACAGTTTCGTGTCTTTAGCTATAGATGCTTACCCACTTACTAAACATCTAATCAGGAAGTATGCTGATGTCTTTCATTTGTACTTACAATACATAAGAAAGCTACATGATGAGTTAACAGGACACATGTTAGACATGTATTCTGTTATGCTTACTAATGATAACACTTCAAGGTATTGGGAACCTGAGTTTTATGAGGCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +%%()#$&(%'&40)$)%)%4-.+12/+$''&%&&**0#%$(()-1333213540+&%%&#)-,%0$*3552268?AE?;?7:,%%&569??@?IN1:@<89>%.),,4:9$6<33;<:>:442/)&%587+;$('%2'5'>9;A4.@;-4<>--2-&&&%&%&(36;AB=?QI:>FBBF@@E;7>:9?@98':22?=34;301--095%%7659)';598<7F??AQG69-.9?>E;HE@;H;0FFJ:9AIECCHI>41->/@A@>:94-$.06<=D@7:GA6@=)*(-484=B>CDDAAFEFC@AAC;CHG?::?858635/6:>3C89A@>BAAFEC@67;==AFDB@14* +@SRR11410539.2339632 2339632/1 +GTTGTACTTCGTTCAGTTGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACCACAGCGGATGGACTTACCCTCTTGAACAGCATCACCTATATCTAGACATCTTTCTTTAAGAAAGTGATGTCAATGTCACCTAACAAGAGTGGCAGAATCTGGATGAAGATTGCCATTAATGTCAATATAAAGTAACAAGTTTTCTGTGAACTTAGTTTCTTCCAGAGTTGTTGTAACTTCTTCAACACAAGCTTTGATTTTCTTATCATCTTGTTTTCTCTGTTCAACTGAAGGTTTACTTTCCAGTTATAAATAACTTAACTTCCTCTTTAGGAATCTCAGCGATCTTTTGTTCAACTTGCTTTTCACTCTTCATTTCAAAAGCTTGAAACAAGTTTGTCATAGAGATTTTATCAAAGACAGCTAAGTAGACATTTGTGCGAAAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTAACCGCTAGCAATTTGGC ++ +&''%$%%%)(6@+9157*'*&'+7;;@+E(=72;20*+*$$#%%%-)5;<>;A=9BF=;<4:53.FADE/*804:?=CFF%?ABA;;2./GAECKBBE;>A67<>DA;BCCK<;<>IHBB;<8??CFE@JO62C67B12=16OGEA?998/=BBEDFIMCJB.7F<40=:%9><=333A@;A6?@A>E@BA5BEFFCDEHCC@FEC<:<:<97:58HF;FEGIE@9?0>>>6((8?A@@A=?>>:;22434@AF@@72;AFDDBED+;KP?0D<<;?6AA=@74>?M>9A6.'4''7?DEJ5A<4..,$.?A=BC=9;<;E?CD9@=421/9;/+=,?=<6--,2%&)*%*$$#"%#$$ +@SRR11410539.2467772 2467772/1 +GTTGTACTTCGGTTCAGTTACGTATTGCTAAGGTTAAACAAGACGACTACAAACGGAATCGACAGCACCTCATCAGATTCTGCCACTCTTGTTAGTGACATTGACATCACTTTCTTAAAAGTGTCTATATAGTAGGTGATCATTGTTCCAAGAGGGAATGTTTCAACTACTATGAGTTTATACCTACTAAAGGCTGGTGGCACTACTGAAGTACTGGCAAAAAGCTTTGAAAAGTGCCAGCAGACAATTATATAACCACTTACCCGGGTCAGGGTTTAAATGGTTACACTGTAGAGGAGGCAAAGACAGTGCTTAAAAGTGTAAAAGTGCCTTTTACATTCTACCATCTATTATCTCTAATGAGAAACAAGAAATTCTTGGAACTGTTTCTTGGAATTTGCGAGAAATGCTTGCACATGCAGAAGAAACACGCAAATTAATGCCCTGTCTGTGGAAACTAGGTGCTGTCAGAGATTCCGTTTCAAGTCGTCTGTTTAACTGGCAATACGTAACTT ++ +(*+%&$++)&$&&&#&*44)(.<458??C@A/E=;44'+(('2-62/.%1+-;7',(4;979517>?=@D<==924)()149=-34.0*('*335453):9:D;9*A$41234$'$'$%%(+-5:++<=;DGA*/81B>B,A>@AADC<6;442-37=6:=:0(30'64354*9>9>F@;;:BCB6=C>?DLMB=87@@BAA=5@=DDC?A=>ABG<9''6=;??A?B=:@67;%:01572FFE@;9@BH,%??BCC(GFDE;.-15/&)))0,,786>77;B:61.)*&,88;33-,:;6649;417689;A<9=65@?.472*%%'02=@7:8:>3##$'*/*'9-2BA>;2++$*+-0./=>@53**. +@SRR11410539.2285457 2285457/1 +CGGTATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGAGAATCGACAGCACCTGGTACCAACAGCTTCTCTAGTAGCATGACACCCCTCGACATCGAAGCCAATCCATGCACGTACATGTCTTATAGCTTCTTCGCGGGTGATAAGCATATTAGGGTAACCATTAACTTGATAATTCATTTTAAAACCCATCATAGAGATGAGTCTTCTATAGGTCATGTCCTTAGGTATGCCAGGTATGTCAACACATAAACCTTCAGTTTTGAATTTAGTGTCAACACTGAGGTGTGTAGGTGCCTGTGTAGGATGTAACCCAGTGATTACCTTACTACAATCTTTAAAGAGTCTGTTACATTTTCAGCTTGCTAAAGTTGCACATTCCTACGTGGAATTTCAAGACTTGTAAATTACAGCTTGTCATAAAGGTCTCTATCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACACTTAGCAATCTATCTTTTA ++ +0%''$$#359=>E:2*-DECBACHCJ=;>?<312')&*2/899@;61/2;@@?D4;2626<=>=36.43>8<>C@<<83,*&(-?DB@C?9;?>@19*'655=>E0@588:A@611(.+''41,3-3?@@;<=A@>>//0<7735FG?>678:@AE>+,-:<@=><<@CA*BDF=>>AEFD9::?98:AE>>>>7A>B>ALB=>@DC=(+B94???>D?AD@A@?DCG73:-62=<>78;22=?B@BECACA9+.AB@A>8?;<=7:;?>CC>AAB=CD-1-64<9>G?BBBB?J18-,$&&#"+67/9--#**48>?;>A87AA7/E9:>=:62777*<@=6489?ACC@69=CCIE@CB<=;@6??A@A;?@B?>C>8=24--/<=,EGD78FBD::;;:<+GD4BC@009CFA=>356,7@)(CCCCB@>@D2BEB>9%%.*37:HC>8:55B??@=KJ=();CIEEH=HHGEDAHG?DDC@@=@A>BC>=<;@DC:;HDFCDD;A=?CC;CECCPP?GF;H?B9CGIPG11HMHGKKH9>8989>=&+)&#%&%+069=:BD:#('**&&$)'&#%',&&**$$%$&**+-.9;B>@>1&, +@SRR11410539.673633 673633/1 +CAGTATGCTTCGTTAGTTACGTATTGCTAAGGTTAAACGAACGACTACAAAACGGAATCGACAGCACCTCGCGTTCCATGTGGTCATTCAATCCAGAAACTAACATTCTTCTCAGCGTGCCACTCCATGGCACTATTCTGACTCCAGACCGCTTCTAGAAAGTGAACTCGTAATCAGGGCTGTGATCCTTCGTGGACATCTTCGTATTGCTGGACACCATCTAGGACGCTGTGACATCAAGGACCTGCCTAAAGGAAATCACTGTTGCTACATCACGAACGCTTTCTTATTACAAATTGGGAGCTTCGCAGCGTGTAGCAGGTGACTCAGGTTTTTGCTGTATACAGTCGCTACAGGATTGGCAACTATAAATTAAACACAGACCATTCCAGTAGCAGTGACAATGTGCTTTGCTTGTACAGTAAGTGACAACAGATGTTTCATCTCGTTGACTTTCAGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTCAACCTTAGCAATACGTAACT ++ +*#&&+**29@?=H?7=;A<:4B>AD?AE897DPLFI?,&%'*?DCG@?JKI>=:E:BDCGFEAAF9CDAQF@DH?A>6<;?BE7?1744@@6FNFBAGHHBDEDNHI=6@->>HB9:&&<,/%25;9/:1A@A<)*($%&49;@C<3--/*.@:9/93GEEH@IB><53,*%7-:;:2088&&2+2:99355:A@EMJ:CGFDGCAF@EHBC>B2+>**.427*+12>A>?-)<,-33<:;C:?<8>8%,4:>>>B>BF?EBEKKB???DGFFEIB>**/GADE=>?;@7716=:;@;>EKHE9*(C?;:1/)1/,57D=8A7;02<79EC7./4/',+2?::0<89D/*>)?DMA>CF<=ACA?@?88FEG<>?3@?>BB@==/4-54'/1-3@@3487$$(+*./100>@BGB838@<=:@@C;EADA?@G11--1)9&6>>CHB<@@GIB998HGC<89897)'9)*%%%10','))68;DCHA>HI=G=====.?GG=?932412'&&1+9AB8:%,$0574421>DBA@B=24-$;;;7?E4>09:67@B54BD<=BDCE;49?@?@MF9BEF@FFL92>566;==8<3>1200=@ADDEIKCEB?=FFJE?;@;6.4ABC7:>BE@DKFF>IGFFEHHAA;76.=?D=>KBFCC44<>FDG@;>D=:ABICBHD==@@IJH;>DFG<55EKGLC>>994<=::65;??IG>>AE89G<@A8@>D@<<5>43&(%%),-.57;:77>>?4?013<:>06+526CFCBC=6AB0:=?CJI;)*%%$%(,;75;@?8215*(:ABBB;@@44?;EC@@@81:5:=:7>=?;?9><8567;>A@?><3765D>=9;;<<%:@>:9?<33228@@><::;+-1='0*8879<=A?B?@FG?A<>BGE@A?9DDAFD.%,$0&%&#'-..((6/)%%%% +@SRR11410539.565909 565909/1 +TGATATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAAATCGACAGCACCTACTCAGTCAGCTTATGTGTCAACCTATACTGTTACTAGATCAGGCATTAGTGTCTGATGTTGGTGATAGTGCGGAAGTTGCAGTTAAAATGTTTGATGCTTACGTTAATACGTTTTCATCAACTTTTAACGTACCAATGGAAAAACTCAAAACACTAGTTGCAACTGCGACTGAACTTGCAAAGAATGTGTCCTTTAGACAATGTCTTATCTACTTTTATTTCAGCAGCTCGGCAAGGTTTGTTGATTCGGATGTGAAACTAAAGATGTTGAATGTCTTAAATTGTCATCAATCTGACATAGAAGTTACTGGCGATAGTTGTAATAACTATATGCTCACCTATAACAAGTTGAAAACATGACACCCCGTGACCTTGGTGCTTGTATTAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTAACCTTGGCAATACGTAAC ++ +%,)'%&$7=B@;?=EEDE462(()/;D?>>-))/.-&%-$-/002-.(74F9:C@>922AFC=?A>5B-D=A=>ADAHF36=52*-)8-.3582:;D-<58;954,0++86*+)&%++,:D;KF><87A3=>G=>62E..AFFFD>>4178.9BB44<(1;+.,-523+469:5413:;F?>92,)%',327<:::/:D>)21@9<@@--7-/$%&&++,++;A?A71=522454311362),3.@H??@67=>8)-1)(+++8:==CE0/:;.E8AB@22>A?@>>77@<868EFMHF:,0(*0A@<3FF9:97=;4968((121BDAEA8<>BGB,=FAKC@014**(:;14JB:99@7783FGJ57BBA5:79:=<5334,,,022;A=:,2.35??>F%+&7/)-*%,68=D>?C@>?@F5.=>CFDEBDH?;:88.*$&)&*,25-->==3?<975?<;:;DGFFC//0//24>CBCFE?GA=;<.,.'(2667849=JJ988571554.$%&(*788A?I@F@C=*5936K;?DD8;BGHH>DD44??@7%'FGC?B=%%/36,$2/)&08:*6:?E<@@668;9=BDDC?QLJ@;=966HFEC954?DE9;/*;?AB?AC4:-?*.@C@'(B7>=BFEBA;?DEFEEA88<@9=D;ED>@9:;7798788<4+''))'%(65B@9IIDFD?EE;?:1::=85*))/294>5=;5::<9*22589B>?A@?:E57@4GLMEBBCF9J@:;A<;L?41057==);A44A==23(&((-679DGC>?>A?C>>D?@?@>==99<<89D?<()' +@SRR11410539.2204217 2204217/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCTGGAATCGACAGCACCTCCTACCTCCCTTTGTTGTGTTGTAGTAAGCTAACGCATTGTCATCAGTGCAAGCAGTTTGTGTAGTACCGGCAGCACAAGACATCTGTCGTAGTGCAACAGGACTAAGCTCATTATTCTGTAATTTGACAGCAGAATTGGCCCCCTTAAAGCTGTTACAATAGAGGCCATGCTAAATTAGGTGAATTGTCCATACTAATTTCACTAAGTTGAACAATTTTACTATCTGCATCTACAACCTGTTGGATTTCCCACAATGCTGATGCATAAGTAAATGTTGTACCATCACACGTATTTTATATGTGTTATAGTCTGAGCTATGACAACCATTAGTTTGGCTGCTGTTGTAAGAGGTATTATGTTCAAGGGAACACAACCATCTCTTACCTGGTGTGCTGTCGGTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGC ++ +-/13)3+9:=<23)44=412<;:;?B..:EBIK?FDEDA=>=@56G;>6650B::<=<=858./=8=7.,0/;99,)BD<9ADFB;6=B@B>CBEIEJFC22'%;:@46<=,99A?BD=BB=CB??B>AFDB:8;<@94218(())*,''*?@=9@::CB2ABE+>'.0<>AB@DBDHG-?;66*,6&&&.7569?;?E@<>ABLDFEC>?;@??<=@AA794,77?@?;GEN=@>A?HHABAHFCIDGAD:;;A>AF56C@7=8;<@9>>$>=CIIFEJ@;>B:=D@CCGCG;39-/&&#.2;=9855:<2<933>EA'1=A:>FE9@A;%&7087FEDEDACD-4()>BA:@::;?>8,5>?E?>2&%$#$&'($+57<9>,-0053:B<=@9:?@A880804,<;89966)' +@SRR11410539.1607713 1607713/1 +CATTGTACTTCGTTCGGTACGTATTGCTAAGGTTAAACCAAGACGACTACAAACTTAAATCGACAGCACCTACATTCTAACCATAGCTGAGAAATCGGGGCCATTTGTACAAGATTAATTATTAACCACATAAGCCAAGAATTACTAATAAAATGTGCTGCAAAAATAGCTGAAAAGCTCTGGAGTATGATTGCAGCCAATCCAAGTACATGAAACTTACAGTGAAAGAATATATGCCAAAAACCTCTGCAACTAAGCCAAAAGCAGTTAAATCCCATTTAAAGTGAAATGGTAATTTGTATAGTTTCTAAAGAAAGGATAGGTGTCTAAAGAATCTAAACCACTAAGACAAACACTTTACAAGGTAGAACCAGTACAGTATTAGGTTGCAATAGTGACAGCCTTCTCTGTAACCACGAAGGCTACAGTAAGAGAAGGCATGCCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTACAATACGCGTAAC ++ +#$((,30125;=E@>,+.-3+735476=<=3A>;770*7)*87=21*3<934+%&%%(589:85/..6::@A?8976*9<=>))*,;;A@*9>?:<*2A9868;=H@>:G>?=>;==?=?48<2232(-$$**&12&'+1..66@?CG?BC:<01.#$(&''((/.,'*-0(')%%&'((((,#,07:A66:++,$$$-.&&:7873-,0,+)))$%%$%&+34202(>C<@38,,4476,(')+-:?54%-9@=?=99@@<036;AC:AA-'*/61??;=C<>>DI<:C@@1;0FG,07(%@?B83=9A>:A8IS;+C?36:=?@@BFA>CEC?<89><@$$&542--+$').+A>?A;@9,'.)**039@:==?<<9745/-*#$%'+0,0263/--+)##'&&$%'*,.'2667,,+5+7;>793/-.00-0(AA5+0;CDLD?<:58899:9=9112%-%*$%$$1.101..&'$ +@SRR11410539.1812663 1812663/1 +GATGTCACTTCGTTCAGTTACGTGTTGCTAAGGTTAAACAGACGACCTAAACGGAATCGACAGCACCCTACACTATGCGGGCAGAAGGGTAGTAGAGCTAGACCAATAGCAAAGAATGACTCTTACCAGTACCAGGTGGTCCCTGGGTGTAGAATACTTTTGCATGTACCAACCTTTGATAATTTGCAACATTGCTAGAAAGACTATACAAGGATATTGAGTGTTGGGTATAGAAGCCAGTAATTCTAACATAGTGCTCTTGTGGCACTAGTGTAGGTACCTTAATGGCATTACTGTATGTGATGTCGGCACAAAATAATCACCAACATTTAATTTGTAAGTTATTGTACCTCAGTAAAACAACAGCATCACCATAGTCACCTTTTTCAAAGGGTGTACTCTCTATTTAATACTTTACTGTTTTTAGTTACGATAACCAGTAAGACATAATTTCGGTTAAAGTGGTAGTCTAGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTATTCTTTATAAC ++ +)%/&&$#$$&&%%'%#%62()#&$),58:24,:67;?AA>A<5)))$)#'02&)%(:<;CC>B?:9C==EHI@C56>98<7624+,,)$%#$$$$&#&,8=40D/2&96696+,000+(%%,'97A9:=A::;77;D*;3@AA;48::,,-'+4,+$''%$%'',88400.--046525;00<>@B=55$),,-..);<D;<694;.$9<725775.%,.147?A889?87//6-)&68,,;9>:>??CI87.0&',-A/54?-4(:45:<8#%%%66;E??A<:@AB3434870)1&&,1)((,$%$$# +@SRR11410539.2462459 2462459/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAGATCGACAGCACCTTCCTTTGCAACCTGAATTAGACTCATTCAAGGAGGAGTTAGATAAATATTTTAAGAATCATACATCACCAGATGTTGATTTAGGTGACATCTCTGGCATTAATGCTTCAGTTGTAAACATTCAAAAAGAAATTGACCGCCTCAATGAGGTTGCCAAGAATTTAAATGAATCTCTCATCGATCTCAAAACTTGGAAAGTATGAGCAGTATATAAAATGGCCATGGTACATTTGGCTAGGTTTTATAGCTGGCTTGATTGCCATAGTAATGGTGACAATTATGCTTTGCTGTATATCCAGTTGCTGTAGTTGTCTCTCCAAGGAGCTGTTGTTCTTGTGGATCCTGCTGCAAATTTGATAGAACGACTCTGAGCCAGTGCTCAAGGAGTCAAAACGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACTTTGCA ++ +$**%)(//0(:>*4+87:90.11),4>A@6))38:956/58:/:*+/%6:;99744566:5:*1*,5=B44IAFGECFB<>=A:9;>/@@A/<98739BE@A;ADE<22A@CA555=:5756=AD479?AADE>>:=3:99FF5=AC2;;5099274..33/.*-%$**+14;?D?FD?>?<>5;D@ACGB98=C?.)&&-*02>?H@D><11837B:B@@A;:4400/?.-4AEA?7;4456?,3<87:0103@?C5=>D??@9.**-+1;ADKKDFC931;<@A9:-$8.A34B=(>B>>GG7HD>@BC?@GG99@BFEIDAJJFJGC?7/%%).4?CE?>=>=BC;4CC=A1>DG+%$707(*%%)$(&3=<8?54S?AE>JEJ?BC@<@A?A<=EGG??BCCCCB>66:>@9:83*...*.' +@SRR11410539.155783 155783/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGTGTACTCTATAAGTTTTGATGGTGTGCTGGATATTACCAACTGCACTAAAAACTCTAGGTAAATGCAAAAAGTCACCATTAGTTGTGCGTAATATCGTGCCAGGCAAACCAGGCACGACAAAACCCACTTTCTCTTGTTATGACTGCAGCAATCAATGGGCAAGCTTTTGTCATTAGTATAACTACCACCACGCTGGCTAAACCATGTGTCAAAATCAGCATGTTTGTTAGCAAACAAGTATCTGTAGATGCTATGTCACGAGTGACACCACCATCAATAGCCTTGTATCCTATGATTTCACTTGAAAAGTCAGTATGTTTAGACATGACATGAACAGGTGTTATTAAATAGAAAATAGCAGCAACAAGGAACACAAGTAGGTGCTGTCGATTCCGTTTGTAGCCAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +%%24&85;>B=7G<61:@>/;683363>;77/;36031@ACDDC??C@=CAF?BAF.:.(EDE=45GJOOB>-E-88@?7,=89:FE5448>AA:9/.0.1,3*:688C@EB@995B77836?CGG>HDABHDD9>479:53*2,,()*237:@D=>?A@87@EI<3CFHB9CAB446>=38+ACDGF>78,,1./<@@4,*<965.BDE@:?4;7>CC964/1&3989BA??72+-+(-+84463<:<@92++4-9=B?6=<:28((8>AEB@;73:<8/<,,+<7;;@B<;?66:;4<>>?@KAC33277?B@8>B?@==BC7>$$4)*&@BB@FC45=6B85)%%%%&469949:::@AA?@@@?6A)*23.>>=7/*$ +@SRR11410539.59239 59239/1 +ATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTCGCACAAATGTCCTACCAGCTGTCTTTGATAAAAATCTCTATGACAAACTTGTTTCAGCTTTTTGGAAATGAAGAGAGTGAAAAGCAAGTTGAACAAAAGATCGCTGAGATTCCTAAAGAGAGGAGGATTAAGCAGTATAACTGAAAGTGAAGCCTTCAGTTGAACAGAGAAAACAAGATGATAAGAAAATCAAAGCTTGTGTTGAAGAAGTTACAACAACTCTGGAAGGAAGCAGTTCTACTCCACAGAAAACTGTTACACTTTATATTGACATTAATGGCAATCTTCATCCAGATTCTGCCACTCTTGTTAGTGACGTGACATCACTTTCTTAAAGAAAGATGCTCCATATATAGTGGGTGATGTTGTTCAAGAGGGTGTTTTAACTGCTGTGGTAGGTGCTGTCGATTCCGTTTGCTAGATCTCTGTTTAACCTAGCAATACGTAAC ++ +%%&17:0046;C/,&2%)%&$%%%+(3<66+;A><>)6355?=::=>@;=5:,0+1<<=B<9=@B>BA;B11>=:@IF=?>688%'14576'349?:CB-%688'9=B><879=AE>?>11=GJJ>47++'&**+2@@>82/60&&&#$.047@::@C>87,041+''$$#'&)+%''10865:3:2*)'''%'&(.18:8/))(*.,/,-0=@@=@@EF=BA?A<**9=4;?;?:79::;D>GG?61(0:;6++.1+'01?1167C>>><<%977*'562/;.?687B@<:@:C@@?<:<;CA@F@B==>2FHA?B:A=AAB<<43)+*&2453,*2464-8:B;CG;C?:=@4/0)95320.*1;87;)-$'#$%$%%%$().1()2**8:?A:';''*2945:<:>>HG=FAE@@@<37::>=A/'126:@>C@<>?C:::58::?>6:574733*8789;&&8==6.1359;=;())1AAGGJIMG9:BECGHLC679E89@;12=@?:8-2;:;HADBEDJGD;BEA88>95%%+4&&$$%(#(:5>E=>:>I;&*4)'&@@-*&&?757&0)24--(#)$$%%#$%##%)*63/;*88'%%,,59==DC7:;:12;<9=9;<@9/<@=..&%3><:F?7::32%#-6FCJEEBD;;=;879423=>=F>82)*## +@SRR11410539.1510751 1510751/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCTCCTTTATCAGAACCAGCACCAAAATGTATAACTCTCATATTATAGGGTACAGCCTAATGTTAATGTGTTTAAATATTGACACAGTTGAGTATATTTTGCGACATTCATCATTATGCCTTTTTGGGTAATGTTGCACTATCACCATAATTTGAAGGTCACACTTTTCTAATAGCATTCTTTGCATTTTGTAAAGATTAGGCATAGCAACACCCGGTTGCCACGCTTGACTAGATTGTAATTTTGGGTAAAATGTTTCTACATGGCCATCTTTACACACCAAAGCATAAATGAAATTTCTGTATAGTCAATAGTCACTTTGACAACCCTTAGAAACTACAGATAATCTTGGGATTTTATTATTTCAACAAAATCATCAAGTAATAAATCAATAACAGAACACACACTTAGATGAACCTCTTTACGTTGCTGTCGATTCCGTTTGTAGATCGTCTGTTTAACCTTAGCAATACGTA ++ +(%%&,.-+,10321-(4@CC;=?I=B@D?-.2HMHDI>9,,/,/.+*3335:8+//210/42/13377A6>6::DE3.6@01@B4F+:?BBHHAC00179:@-9+:HA>B?CB%>74)>CDABDG@HBDHAEA==@DCD63;<?C<<=>-7+9??CEAF?@?LGMBDCA@KIED>?*('<=,,;4(8<7;@959<@;78=GC?B>>6555.(#'%+$%->BEEB@A?/5=7131:23?C;=8424A;>B=@?BGFD>'>6:7@GIJ=:D>EG@=B@LLEBAB@?:/:790>AC=5:4=?569C:;6()54.-/++18156B==BD=AA<>86'(&&>>-.;>?=A:?;9F9<;?:;5<>8-0%%$''*<)<942(,0&'++79:02++(+'&''&$%('+44B@9BCGCEAD8<8=++$%-&.3;?AE<<<>C@?=>C:AAB?>>8-' +@SRR11410539.2040419 2040419/1 +CGTTGTACTTCGTTCAGTTGCAGCTACTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAATAACGGTCAAAGAGTTTTAACCTCTCTTATATTTTAACAAATCCCACTTAATGTAAGGCTTTGTTAAGTCAGTGTCAACATGTGACTCTGCAGTTAAAGCCCTGGTCAAGGTTAATATAGGCATTAACAATGAATAATAAGAATCTACAACAAGGAACTCCACTACCTGGCGTGGTTTGTATGAAATCACCGAAATCATACCAGTTACCATTGAGATCTTGATTATCTAATGTCAGTACACCAACAATACCAGCATTTCGCATGGCATCACAGAATTGTACTGTTTTTAACAAAGCTTGGCGTACACGTTCACCTAAGTTGGCGGCCATACGCGTAATATATCTGGGTTTTCTACAAAAATCATACCAGTCCCTAGGTGCTGTCGATTTCGTTTGTAGTCGTCATTTTAACCTTAGCAATACGTAAC ++ +'%%&&)++++09B6.&(%&%&%#&*$&'%&(:6::@96,,6+0.-%'++-*0150:9;78,'740>:E?BHC>@?BED55G@.*,.?C6699:4D=CCFA>C@A93=*-A3/@;:=E?@BD;4:BA?B==FAC?EA?>?@;)*,89:?C==<<:&'$%'20.'0;>9957::;;;A=?DFA3/,(;5BE<@>CA<;@H7;=8:DB=DHC?@=<=@E:@A:=DGJGHG?;B<77<2).&2;7.&%*543A3**=:9>FEFCECAD@ABG>205*+-*-01:5?=?A@7865/.5=540-%%%26,&5,+%?@LF=;(->22:<<;<8%%%%1237AMMO=A<@:GE692+D+3-970678>F=6>:>%:<=9@@:;=C5ALFECCCB;>9<(%&*>?CEC@@19&167A=CBA31& +@SRR11410539.279380 279380/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACGGAGCGACTACAAACGGAATCGACAGCACCTAGTGAAATTGGGCCTCATAGCACATTGGTAAACACCAGATGGTGAACCATTGTAACAAGCTAACACTGAAAAGTCTGTCCTGGTTGAATGCGAACAAACTTATACTTAGGTGTCTTAGGATTGGCTGTATCAACCTTAAGCTTAAGTACACAATTTTGCATAGAATGTCCAATAACCCTAGAGTTGAACATTACCAGCCTGTACCAAGAAATTATAGTTAGACACGAATGAGTAAATCTTCATAATTAGGGTTAAACATGTCTTCAGAGGTGCAGTCACATGTCTTGGACAGTAAACTACGTCATCAAGCCAAAGACCGTTAAGTGTAGTTGTACCACAAGTTACTTGTACCATACAACCCTCAACTTTACCAGATGGGAAAGGTGCTGTCAATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACAATAGCTT ++ +1.1340/56;8+++<89?>4>FCBD.7$+%%4/.571:78,71486/1;<20/12::7./1110&&.68==>@D8@F>?DHHHGABFAF@9,-;%%;@;?ADDG:869;7>99C<>=B?G320-/:?DEDDHEDBE@GHCA::A=>DB=@9A?:2.*<:;83A**7;=<,,9;<<;=9C=6DCDE?DOH85)7739?8678@3-'89BA@3'&#><>=<>AD=?@?=F8A@F>?=76$%&))))(&$%%68.4(%*5005'-$7421/:;@.3'0./.23:;?@8,.%+0&)89@61@-333A3.&$&'$&=?B=>I>>?C(&;;:<(88*9:<@4-9$%(%5BE44G899BD678A>5/<:C603:2:>>879<;=@A=3233*03<55GAC@C>-&::?C:@??@D@CC9@$=;A=;:936$&%69<8?8/+09770&'3;9:<;??<:8/0'+,,%'#%%%'&""$ +@SRR11410539.2283803 2283803/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCAGGAATCGACCGCTGTTGAACCTTACAAGCCGCATTAATCTTCAGTTCATCACCAATTATGGATATTCAATAGTCCAGTCAACACGCTTAACAAAGCACTCGTGGACAGCTAGACACCTAGTCATGATTGCATGCAACTAGCTACATGTGCGTACCATGGACTTGACAATACAGATCATGGTTGCTGGCCAGGTTTACCTGTAAAACCCCATTGTTGAACATCAATCGCAAACGGATTATAGACGTAATCAAATCCAATAGAATGATGCCAGCAGGCATAAGTGTCTAAGCTGGTGTTGGAAAGCATGTGGCACGTCTATCCGCATAGACAACAGGTGCGCTCAGGTCCTATTTTCACAAAATGCTTCATAGATGTCAACTCAAAGCCATGTGCCAGGTTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACGCCAACAATACGTAAC ++ +5../3<6;?BA?I+:1:52)'$(.3:--<221@DD@C3=<<@?B?79:656%)'&*$,8;:2/2'&1=@BD@@330,&/232=>7<;8?D@8@@@?@BEEFD;5&+7KJI3?8853:))9368A*+8>;:67<88?AA;?ECAB5.:AC>5.1/1+(-58@9A>><=4AFCAKJBEI>E3(',8:73221B<=@--26=..:,,*(*+:>:,699E?9890&$$$$4=??DB?==DA...56584*9///''=?A=@<,AA@BE11-*%*'(;<64/0.5.('%#$%$%$)53('*..8;,:A?AB>?A.75/=2.((+)*;<66:95447@=D@89><>978;>57GHDG22;@BHG?D@F@94CABBEDIKKBFC?@BDEF;<41%(>AB@;A?=@?AC@B<79:++))('43/-++7:?CF>--E?DFD=?>?46'-*''8:77*;A<=17D>>B7>>AEGEJJ?C:=8111:>62@FE@$#$'09>=?A2?77;E@6:B9.9@=::'.&&.//0;0?C<-:8:?EGDHG:?;:5:99B04<6DDIFEFKGIG@ABDFG<=7CAA@8016589@H@34A;:>=//1269:<7;<=;@@C>:775,2,0A5;CDB:9311*'&,$%$%&,05/0)%+37<<8=CCE8FFGD?BB=;==<4/'$#6?BGF8=D;GBPL=E;@7C@C4FD>@=BCJ:6418;8$-$'*('&''0;?;<9480055*)()%)*,*5C6;DEBDE;A@?<<<76>HNA9;8ADFHE@DAE=;<<:+,'#**/-*3%/39@>AC<9<>7A;@:2<::;;350203$(.+.3225957%$345%$+@CB@=>C=?AC?=:;AG8@15>B899;;;=HDC<>-&&(+74,AC=@?@BB9273A>7A';B;=BB@46/05.06&%&$'276./.>?8;B=@<@A->E=4:<;;:',6.9A>7<=AAEGJJCBFK@H<20*?C8=C?9GHJOFHCD@?CAFBFBA:876&LIB66?;1..=@=)0,++,1:97AA;<@@FI@:979:CC;=GB64//149B)-B:;GFMD<==**A((5@A><>('$(%&(377?8+%2233,)77CBEEC@?7=883AF<-+429=>>BFC;=6><5:-.7=;B;>=;;464&)79;;51*%+3:<:75255666,)+3$&'*)+*-+$),(('(+-&$$%%).14$$';:?<>H@==>;==<,,($%'#&%-958?;79>92+<;7735>=1)'6.5464.),&&&&&,+)%&$(=>97-1346A@,,-++'*'-%%059@<68;;=12/%(233;:9466/<;=;8/+%../2488--#$'687B@<8(&7+08662,9++.%&19)&5886>8:8((/(29@55@?>>?=442611164;1..*3:9*>==,,777:9BDCCB/:%(36<88;)@=?B?999>?=::>?OE7%+)&')6331=.**.-.5:==31/6=BAD<(*&-)43'&.,**+8868874-+$)$(((,%&%$(%$'% +@SRR11410539.116738 116738/1 +CAAAGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAAATCGACAGCACCTATTCACTTGAGGATACCTGGTACTGGTAAGTCATTTTGCTATTGGCCTAGCTCTCTACTACCCTTCTGCTCGCATAGTGTATACAGCTTGCTCTCATGCCGCTGTTGATGCACTATGTGAGAAAGGTGATAAAATGTTGCCTAGATAAATGTAGTAGAATTATACCTGCACGTGCTCGTGTAGAGTGTTTTGATAAATTCAAAGTGAATTCAACATTAGAACAGTATGTCTTTTGTACTGTAAATGCATTGCCTGAGAGACGACAGCAGATATAGTTGTCTTTGATGAAATTTCAATGGCCACAAATTATGATTTGAGTGTTGTCAATGCTGATTACGTGCTAAGCACTATGTGTATTGGCTTGACCCTGCTCAATTACAGGTGCTGTAGTTCCGTTTGTAGTCATCTGTTTAACATAGCAATATGT ++ +,$'%&$$$)065>:;CFC;8?;8<=?B551GCABG@@66;398;994<<4.%*;9=?D=DDFAF;:96.%$"#$%$&1%'49:EADCB>:?A96)&79588GC>>?DFF???6;>8>>.CBFGDFFCACGCDIEGM@>FFE<@)99998=>G@@@??EDCE@CG67;;6*-+'%$#$$+0287''-.9;;2'6,.$%(')''5788486:7//99<0,181A2>ADEEHCAD@?@>H;:5533;>=?CDD@ACDA4@+:9B=:;35;;AB@DC;?>ADGM;0;=9-:;8****777:>?.,?>@EEGCXK>=1BDEFE626<>20,'''&-=:88-).7;885257447.%,+0))#%)+*-.**)56=0414,*1(2>1/1)$&$)>3<7+++,&&&$$$'&,'(' +@SRR11410539.2444711 2444711/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGGCGACTACAAACGGAATCAACAGCACCTAAGGTGTCTTTAATTCTCGCTTCTTTTCAGAACGTTCCGTGTACCAAGCAATTTCATGCTCATGTTCACGGCGGCAGTATACACCCTCTTAGTGTCAATAAAGTCCAGTTGTTCGGACAAAGTGCATGAAGCTTTACCAGCACGTGCTAGAAGGAGTCTTTAATGTACTCAAGGGTAGCCATCAGGGCCACAGAAGTTGTTATCAAGCGACGTAGCGGTGTATGCCCCTCCGTTAAGCTCACGCATGAGTTCACGGGTAACACCACTATGTTTAGTGTTCAGTTTTCTTGAAAATCTTCATAAGGATCAGTGCCAAACTCGTCGCCTAAGTCAAATGACTTTAGATCGGCGCCGTAACCAAGCACCAGCTCCTTTATTACCGAGGTGCTGTCGATTCCGGTGTAAGTCGTCTGTTTAACCTTAGCAATACGTAATGAC ++ +&##$$-%789=@JE:3?BDCGC@@@BAA>44%*$+*,()'+*0/+//%%-/016:72(5/39DC>BBB=<=//65&&$#$/2(++)$%$$&)29AA6698=@>IFA>;>G<;:9==><$*,%(6;:56:5207<<6:>F83@**(356311E@CHH;G/>49AA@A:-<359854./DHIFJEDIB>?>AF=@;>7>8'9%<:;:<7#$##$*2::11)1?@D;872)=251AB@@@B>98D@C8@?6/2()(-<>;***-0$)30*+/)66:.29=>@11>CB@BBBJJD=B/25///==..)'(979BBD?@FGC:?7??BVIDCC::6GH@CMH@1@?@3G8.B8;GD>>>@$;=@1+4AABB&'%8?>@BEFFFVQAC:919(,)'%&%&.-*+//-,)-04*:;+4*.59022=48'+307786>@D?BB.2&(&%'%'+6;43=227;<.--+&$'%' +@SRR11410539.1029530 1029530/1 +CGTATACTTTAGTTCGTTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCTTTTCTCAAGCAGGTTCACGTGTAAAGAATTCTCTTACCACGCCTATTTGTGGCCTGTTAATTAGATGAAACATCATGCGTGATAACACCCTTACTTAAAACATTTTAAAGCATTGAGCTGATTTGTCTTTATGTGCTTTAAGCTTATTATCATAAACCAAGCACTCACAGTGTCAACAATTTCAGCAGGACAGCACATAAACCAGGTTCGAGGAACATGTCTGGACCTGGTTTCACGCATAAGTCTACACACTGAATTGAAATATTCTGGTTCTAGTGTGCCCTTGGTGCTGTGTGCGTGGTGCAGGTAATTGGCGAGCGGGTCATAATGTACACATAGTGCTTAGCACGTAATCTGGCATTGACAACACTCAAATCAGGTGCTGTCGATTCCGTTTGTAATCGTCTGTTTAACACTTAACA ++ +$$&$%&',-&$+34))14/%%&%'%'%+.+,3?C@;>7@<<0*%%3$'$7:6>'/)*%%&:>A<;5;<><;+;<<77/;:6?8?@:?@C8DB@BCEAFBEA@80''==>6:0@GBGF>B?B>;A?FJF7/()%,;=>@B=44;548039:>9;8+-'('.:5('''&&))$&%$'',)A+/*,36336?AB=@;231)#$$$(,)/&(#&%/120;<:=/>0?CFH@><0='?F@DA=B?<=?6E=6:DAD@BD??=$*,'')&*),546B34A<;8<;7/0/1$(&1&,.#(337/.9?ADC@A:;4/43.0>7@@@9;=677$3688<&%%&*++/21,660%$$$"$%%$$* +@SRR11410539.912453 912453/1 +CGGTAGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTAACATGTTGCCAGCCACCACAAACCTCTATCACCTCAGCTGTTTTGCAATTGGACTTTAGAAAAATGGCATTCCCATCTGGTAAAGTTGAGGGTTGTATGGTACAAGTAACTTGCGGTACAACTACACTTAACGGTCTTTGGCTTGATGACGTAGTTTACTGTCCAAGACATGTGATCTCTGCACCTCTGAAGACATGCTTAACCCTAATTATGAAGATTTACTCATTCGTAAGTCTAATCATAATTTCTTGGTACAGGCTGGTAATGTTCAACTCAGGGTTATTGGACATTCTATTCTGGGTATTGTACTTAAGCTTAAGGTTGATACAGCCAATCCTAAGACACCTAAGTATAGTTGTTTCGCATTCAACCAGGACAGACTTTTTCGGTGTTAACTTGTTACAATGGTTACCATCTGGTGTTTACCAATGTGCTGAGGCCCAATTTCACTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +7,.)+()(55604>'+%2=:3.)AAIJ?=F/0.ACCFH@2-1.7@A@@@BAB>@.3;>;=;=;@>8BC???=AB;<=>:''%$%**&&&459<-95/?.=60?;=>03(48;==JF98(&$.&,$$12233@GC?=6$,58><450+67H@D@CE;=9>85>==JKFCA>:>>?:=>EHC>>==:117666=8@?@@>;9<.%@;989:878639@>=>><((**+@??,>@08:;9989;=??F=8>?>@9479<4-8-;<5720$%287:/200/:>>8?>:;?4BAA33==2.56:>3++1&,,12932)''/*+++-6..1')%*+09;??A?>>/;>=?@;7=:966;<225@A17?:B?:=8:4?6,%)**&+0',(04;=>;EC?B<5@>FC?8<<>5LBBEB;=7?A;=EFB64+0*.7+2430)0&%,-) +@SRR11410539.979866 979866/1 +GTTGTACTTCGTTCAGTTACGTGTGCTAAGGTTAAACAGACAGCTACAAACGGAATCGACAGCACCTTTTGCCTTGGTGATATTGTACGCTGGGGGCCTCATTTGTACTAAGTTTAACGGCCTTACTGTTTTGCCTTTGCTCACAGATGAAATGATTGCTCAATACATACCACTGTTAGCGGTACAATGCTTCTGGTTGGACCTTTGGTGCAGGTGCTGCATTAATACCATTTGCTATGCAAATGAAACATAAATTTAATGGTATTGAGTACACAGATGTTCTCTATGAGAACCAAAAATTGAGTGCCAACCAATTTTAATAGTGCTATTGGCAAAATTCAAGACTCACTTTCTTCCACAGCAAGTGCACTTGGAAAACTTCAAGATGTGGTCAACCAAAATGCACAAGCCCCAAACACGCTTGTTAAACAACTTAGCTCCAAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTGAAACATAACGGCCATGAAAACT ++ +%.0:;:776,+:2/*745597@.8@@866*<=68:9)$*$-%$%($$3447:>>>;)>9+-$,&%'&&''&%&%'$%989,0&)%&#$)(*$%&%)031/')*,&%##&&,(@;>>?C18@CB;4=@D==QH79-+.*,9=A;@=>D=A>@C>66BI7HHB11/0)$+$$$)*34,0(.-&($*-8:5*.01A7:@II?AB497<=()A4200-*)0.(6/67//+-16;DD<%$2;?BBBC=+3%%$$$$%'')+(./,(*(&)*)%):5::/-)--,B?==@@5;07CBA@800-$$'2,++56693426A>@A;B6A86;>=C5;AFF>@@?C?AFC?95,(,,2;@>:>BBBEC>A=F<9+333<=9D668;9<:99<968,0;C11'>445=&%78;89.-***01+-550159=>>AB6A22001=<><)@011AA>@=56)..12'(.2;1210<;9:;)'$%&'$$#%%'$%'#&&'%'('''%$$ +@SRR11410539.1646670 1646670/1 +TATTTTCGTTCAGTTACGTGTATTGCTAAGGTTAAGCAGACGACTACAAGCAGGCTCGACAGCACCTGTGGTGATTCAACTGAATACAGTAATCTTTGTTTTTAATATGGCAGTTTTTGTACACAATAAACCGTGCTAACTGGAATAACTGTTGAACAAGACAAAAACACCCAAAGTTTTTGCACAAAGTCAAACAAATTTTCACAAAACACCACCAATTAAAGATTTTGAATTGGTTTAATTTTACCTGCAAATATTACCAGATCCATCAAAACCAAACAAGGATATTTATTGAAGATCTATAAAGTGACACTTGCAGATGCTGGCTTCATCAAACAATATGGTGATTGCCTTGGTGATATTGCTGCTAGAGACCTCATTTGTTACTTTACAAAAGTTTAACGACGCCCCTTTGTTTTGCCACCTTTGCTCACAGATGAAATGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACACTCTCCATCTTT ++ +(+,.9;78GD2+6-/A74::895757:,-;@FA8:)8679>=;;388=:-1/02037:13.3=::890741*,+&)3&''')&)(&+$'$&**,((97.+$$$.2999-.)$)*0444%)$'$$##&+-.,-03''3$&*.040'&'(09:-/46?;<>=A:FGIC860-85//%-'+652/3**559<;=;<82337<97.(&&562/.,>@::8F;@?@@/6ABID3.)))-.1>><=>9<&&%%%'$)*--4672(10;3<33A@>?FHIF@>>>%:56,*,)547@C>@@BEB@9<0-(*++-57,67<=?@A>=6F>CGAECGD?81;9:4222033,)254:=-(((+'(95*)&&)//?2225,*-568:74547+$%###$$+/775.1EF@CC78,+))))$$'6925CA=87C><=>D3<@A?>A::771/18965./*(359;?;;:259=7666658053356803DC'':B:;8;98B9<:B4314)'8=97,7777-///12&)5?C@CGDHKHICD00///97@@(1'((?BBA;:@=035592;+,/;=A?D?9/.(%#&#&&-0%89=55:+++:;.)-))$%&(45663@C<;-1;:@@>:87C@ADB<@?7<=<)+&%))'#%+(2@A1%:+JMG<://A<<84;<9;:65?..5GEKG;=;A5',995,5>>0''-4:<99GKKCE>>)*,017*%%7;=A@==;7<<8//-47>@>*?6:9<78?A=?C>67.,,,6;B55BEF9@;8==;=B?A=5/683'=:1(64.06)))'(%')&&)%&&'.7-0199B03.//1,,1%%%-.64)8;<><78,,$ +@SRR11410539.868783 868783/1 +GTTGTACTTCGTTCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAAGCGAAATCGACAGCACCTTGATTTGAGTGTTGTCAATGCCAGATTCGTGCTAAGCACTATGTGTACATTGGCGACCCTGCTCAATTACCTGCACCACGCACATTGCTAACTAAAGTACACTAGAACCAGAATATTTCAATTCAGTGTGTAGACTTATGAAAACTATAGGTCAGACATGTTCCTCGGAACTTGTCGGCGTTGTCCTGCTGAAATTGTTGACACTGTGAGTGCTTTGGTTTATGATAATAAGCTTAAAGCACATAAAGACAAAATCAGCTCAATGCTTTAAAATGTTTTATAAGGGTGTTATCACGCATGATGTTTCATCATCTGCAATTAACAGGCCACAAATAGGCGTGGTAAAGAATTCCTTACACGTAACCCTGCTTGAAGGTGCTGTCGATTCAGTTTGTAGTCGTCTGTTTAACAACAATAACCGCT ++ +(..+.*--**38.A$)=@==;AGGFBFG00ABGFCE2=8;377,%,$&.10)1%%%47>=ABFHFE;=9;@=?AB>0IHA>?71?898424/.&$(*+;/-6670=..72,/63=:G>?C5:44376439:CHCE6;.>@EHE8@?@B@928>=AF?>>=>HC>@667@C::@ADB2*0-,30=<>EA8:>;:=:A:HG=88/02635)1021%99===>EF?47:6:A:;=<@--1,,5**,ABG<>BB;??@59???@<0)9:1;>@,,?A=@AA:==A44:=@BAAEB?=H<537;9'@3?=?:A?@B88::;AB@BA798>>;BAACAB0+(1785:58:.=-)+:=CB?>A=B888%(3;;A=A;AB@D)1'..3A20/49;6999;4621,,$$%..-*+01&&' +@SRR11410539.1572026 1572026/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAGCGAACGACTACAAAAGCGAATCGACAGCACCTCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGTCTTATCAGGCACGTCAACATCTTAAAGATGGCACTTGTGGCTTAGTAGAAGTTGAAAAGGCGTTTTGCCTCAACTTGAACAGCCCTAATAATGTGTTCATCAAGCTTATTCCGGATACTCGAACTGCACCTCATGGTCATGTTATGGTTGAGCTGGTAGCAGGGCACTCGAAGGCATTCAGTACGGTCGTAGTGGTGAGACACTTGGTGTCGCGTCCTCATGTGGGCGAAATACCAGTGGCTTACCGCAGGTTCTTCTTCATCGCGAACGGTAATAAAGGAGCTGGTGGCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGGAAAGCGGCACTGATCATAGTGCTATCGATTCCGTTTGCTTAGTCGTCTGTTTAACCTTAACAATACGTAAC ++ +)')*889>B?>=G26/:;?;;>FDE=10)ABOICBDCB?:HABH5040A@A@B339.(*=3:9;'/CD@:(34.//;<84.+(34B@AC::HB>>66BB30))&'(.678;5;=3332<9H7C5@ACABNK5'>??DAJF==<8>:;...11;?>;:42(''&%&(+5::<@:CCD?B>BEDAB?>A>;>:AA>699730-5%$%'.2/'&&8;?4:3-%&'(8<:46/473B;<974&44++++2262%%&$%**+.?6))79;?C//>EDBHB2/*4>IBAA3,445@@8<9)),173@@C?FAECFEC<60;789&';C887:EB10.+'(;:4C4725/)(%(/26*?0&9%)+'>79-%0>77E@8=;?@J3++-22::65;8B@BD?@:;9EC?',% +@SRR11410539.537278 537278/1 +CGGTGTGCTAGTTTCGATTACGTATTGCTAAGTTTAAACAGACGACTACAAACGGAATCGACAGCACCTACACCTGGTTTGTTGCTCACAATTTTGACTTCCTTTTAGTTTTTAGTCCAGTACTCAATGGTCTTTGTTCTTTTTGTATGAAAATGCCTTTTTACCTTTTGCTATGGGTATTATTGCTCTTGTCTGCTTTTGCAATGATGTTTGTCAAACATAAGCATGCATTTCTCTGTTTGTTTTTGTTACCTTCTCTTGCCACTGTAACCTTATTTTAATATGGTCTATATGCCTGCTAGTTGGTGATGCGTATTATGACATGGTTGGATATGGTTGATACTAGTTTGTCTGGTTTTAAGCTAAAAGACTGTGTGTGTGCATCGGCTGAGTCATTATAAATCCACATTATGACAGCAAAGACTGTGTATGGTGGTGCTAGGAGGTGTGGTTGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATGCGTAATAAA ++ +$%'+%%&%$%(%*(..$85$$'&$$*.7+(*))0&5673041)4394-?=@<;479;67?DA9DB;@??/1-,+('+456305$31+.6:<9;0,03:<<$($55-09@CJD?+.))1((;9A:DCDB?A;>=<@=D>>EBDEGB964,,8>A>76558EHDE:=::EF?A?;8-/0/76-$./$#/))1557)'(0106487<==@CE=DA><:9?:C=HF?2=;5=?C@>=3A@@DEE@C91-,)%&((:9=<<>?@@<@B=<388@?=6-33/**626?B99?>;<%)?BDA30?8)0@7888&*#$#&$*7/3040)&&')($%)&&*.1((4#&'$(--.,+$(*12+%0227640-4()-48;51/$%%''3;70)+$$$3--.-++98;?286;;4/;@39<=%%;12<6++*$'(44>?A9>AE<9<56923,-6KBC@:1?=<95.34--22:@@?:@AA=;65;;(+0+;=MG@AA9:;:(((1;?;<=B764>@>?A<77<<,*+,))*,7EE=DCKJOK>FD32/3:.+9B71?23;67/:C22@2*?=AF:565;?<$$(73>?>?:)-)+--,0((%0=97.-%# +@SRR11410539.726080 726080/1 +GGTGGCCTTCGTTCAGTTACGTATTGCTAAGGTTAATAATTATTCTAAACGGAATCAGCCTTTCTCACAAGAGTCAGTCTAAAGTAGCCCGGTTGAAGTAAATAAAAGTAAGTCATTAAATTACAAAAATAGCCTAAGAAACGGCAAACTAGCATTATACACTGTATTACCAGTTATAAGAAATAGGGCAATACTCATTTATAATAATACCTCTGGCCAAAAAACATGACAGTTGTACTTCACACAAATGGTTAAGGAAATGTCAGAGATATAAGAACCCACATGGAAATATGGCTTGAGTCTAAACATTACCATAATAAACTTTGCAAACGAGTGTCAAGACGATGCGCCAGGTAATCCACACTCTCCTAGCACCATCATCATACACGGTTCTTGCTGTCATAAGGATTAGTAACACTACAGCTGATGCATACATAACACAGTGGTGCTGTCGATTCCGTTTGTTTATCGTCTGTTTAACTTATAGCAATACGT ++ +%%1&&(''&''.0>9?GC?82,*)*-64/0-2(,())$%$'&%&),3511/2,30*&&#%#$&%$+))('*%1/3-*%4-@A-/30/&22././.)%$5452+/3,&$(#$$$$&$%$($%)('26==:-9++$2136//-2$*10349;;@@?@=999:*(%%&%*+2/63986,1#&%/05+*-4/6/0-+''($$%$%''*(),+,*-.960067IH?;<;??ABDDDGDEG=00+%%#)-,3/.563/1%%))&&$)#&$#$#(%*))9:?-;((/'-%,''&.&6764?>=6*&&%++$*81)6723-%&.&/337?>7--'2112.--)2:;=>@?B@>A<@C57;<;92/8=15E@=AD:@DDH@7979=4%'''*-161;;A<>GD7##%%)%..1.&%(,' +@SRR11410539.1128691 1128691/1 +CAGTATGCCTTCGTTCCAGTTACGTATTGCTAAGGTTAAACAGACGACCTAAACGGAATCGACAGCACCTTGTGTACAAAAACTGCCATATTGCAACAAAGATTGCTGCATTCAGTTGAATCACCAACAAATGTACATTGTACAATCTACTGATGTCTTGGTCATAGACACTGGTAGAATTTGTAACCGGTAACACTAATAGTAAAATTTGTGGGTATGGCAATAGAGTTATTAAGAGTAAGCAACTGAATTTTTCTGCACCAAGTGACATAGTGTAGGCAATGATGGATTGACTAGCTACACTACGTGCCCGCCGAGGAGAAATTAGTCTGAGTCTGATAACTAGCGCATATACCTGCACCAATGGGTATGTCACACTCATATGAGTTGTTGACATGTTCAGCTATTAAACAGCCTGCGTGTTTGAAAAACGGCCTTAGAACCTGCAGAATAAACGCCAAGAGTAGGAGTAAGTTGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACAACAACTCCCGTA ++ +(%)((($$$2628B=%)%<;0%+)4-45=@8675GKHHK>@>>@;<40$'-/:><@DC>??E62BEI@@AK>8B;9?HJKJ<=A@EEGDCIE@F44BJK<(66@?=DEGECAD=>DC@BC;;A>?(C@@@@,0'('$$(&('6=?;@73:=C@A5?CCC9=9?;?<AG@A@FDECCCHCD776/?:<@>@BAACDFCG@BF??A8<&';6E?AC/?778@983KJHDHB:*.**,...0,(',-.0;77@+59<895A14;@C;76:=9A9??EGCBE*>;@7*/65:?@89/1-),6+0@=>@=?E>511,*(*-246;96B?G@B=DD>=9<90,-27+,**/05-2-((')*-.1E?DG?@.;<$&&&B;;?808?>ABFA@7/@=>=:<=@CBC?%(7=>@=?BC<=42A7FDFC95'()1-,#%%'*&&* +@SRR11410539.1586846 1586846/1 +GATAATGCTTCGTTCAATTGCGTATTGCTAGGTTAAACAGAGGACCACAAACGGAATCGACAGCACCCTATTCTACACTCAGGGACCACCTGGTACTGGTAAGAGTCATTTGCTATTGGCCTGGCTCTCTGCTACCCTTCTGCTCGCATAGTGTATACAGCTTGCTCTCATGCCGCTGTTGATGCACTATGTGAGAAGGCGCTTTTGATAAAATATTTGCCTATAGATAAATGTAGTAGAGATTTATACCTGCACGTGCTCGTGTAGAGTGTTTGATAAATTCAAGTGAATTTCAACATTAGAACTGGTATCATCTTTTGTACTGTAAATGCATTGCTTACTGAGACACGACAGCGATATAGTTGTCTTTGATGAAATTTCAATGGCCTAAATTATGATTTGAGTGTTGTCCAATGCCAGATTACGTTGCTAGCACTATGTGTACATTGGCGACCCT ++ +*(.(*&'//164:-<$'$/$-.4223)%240AEBBF?475,<8=4,?AIKAAAEBB76<=;6AB=HKB=?750'%.$$-.)27>B>;52,*')(&'2-06%%'**3B:>DG52<345?@?A67?7(795BA@>>DDDCIE4.;==?=?:<:EIIAA5B5;3-(*/,7B=?AGGFA@E@??%%;@<)-+'%$###$$$138=??;66DAB644750)2:5589?075;,2*$.##'1222::<-(08B0:56@>:44.41$#$&/12.$%)'7AB;>=<:0:=?C34:9=?+++-.-3/170*)184+%*(')%$'&%,4>;;2--&88;::;--/**---& +@SRR11410539.1320448 1320448/1 +CGATGTGCTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAAGGTGTCTGCAATTCATAGCTCTTTTCAGAACGTTCCGTGTACCAAGCAATTTCATGCTCATGTTCACGGCAGCAGTATACACCCCTCTTAGTGTCAATAAGTCCAGTTGTTCGGACAAAGTGCATGAAGCTTTACCAGCGCACGTGCTAGAAGGTCTTTAATGCACTCAAGAGGGTAGCCATCAGGGCCACAGAAGTTGTTATCGACATAGCGAGTGTATGCCCCTCCGTTAAGCTCACGCATGAGTTCACGGGTAACACCACTGCTATGTTTAGTGTTCCAGTTTTCTTGAAAATCTTCATAAGGATCAGTGCCAAGCTCGTCGCCTAAGTCAAATGACTTTAGATCAGCGCCGTAACTATGTACCAGCTCCTTTATTACCGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAA ++ +*%&&$,%58::>C?C;>FD<<;<=<;>@=H?%3CDDBGG;B9CDDF@>=776&+247?;=?A30A=>A>@?@6=AB>@CCD9::;;))8*5:AHBJ/88108@:KG;=?GG@2=;;3A>ACBC>9;:<85:>,0FC@@A>=:<8;HF:17@+';334*('%%A;?CC?H;>?DE?BBC?HFF;@@34DFKIAAB0B)&'1?=5228:D5F?.E=?IA=46:=>3:F4=AI>>@=8=;A52?EGKC==>EF83635-%3BAA@@AE;3;62),2==EGFD8A?CKFB:.@58+(66&$$&=HJ@A;EFI=?LA;B?>ADBIIGCD@EE?:3<1/+*=;5&/ +@SRR11410539.2397387 2397387/1 +CTATCAGTAGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACTGGATCGACAGCACCTACGAGAAAGCAAGAAAAAGTACGCTATTAACTATTAACGTACCTGTCTCTTCCGAAACGAATAGTACATAAGTTCGTACTCATCAGCTTATTGCCTTACAAAGGCACGCTAGTAGTCATCGGTTCATCATAAATTGGTTCCATTACTGGATTAACAACTCCGGATGAACCGTCGATTGTGTGAGATTTGGACATGTTCTTCAGGCTCATCAACAATTTTATTGTAGATGAAGAAGGTAACATGTTCAACACCAGTGTCTGTACTCAATTGAGTTGAGTACAGCTGGTAATAGTCTGAAGTGAAGTAACTGTGTAATACAACACAGTCTTTACTCCAGATTCCCATTTTTCAGTATAACCACCAATCTGGTAGTCATGTTCAGAAATAGGACTTGTTTTATCTGGTTTTATCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +)'%%'%%$$''%&&&(38;988675201/-.(27$(6620@B7;017=@>?7?=:8,(''(1051,)*'$%+.1)(%)$),'44<<+@4@5)'9@ECFJGEC??7153467@@D@?@AE=?AAFA6<55F6...1,$$,-7.1:;;8:@9<88/%%&#$##(0/56$.>=09*))%$&$'&%%*'06B@DB=C687::;A+18:FHHEAA>GEAA@=>BD%B@DFJEDE89BAD6996>?B<>?B1:4CIGIDCDC34FF?ACFA3;B4,65B@;:C-(2532:<=A9:B:=860&-.)>A;6@99>DBCA89794/;666070++-331'*&&)/449:/-')1844'161008470-+-.1548=C8:37:?;/&+2&17;,/&%)+1?AIH40'*>;AEFFD0>>B?7D=59AC@==B?BG4<758873418?CB=?:@??/-22=>:=B?>:9@66>=@8,:>BC>GGA>63&* +@SRR11410539.1200022 1200022/1 +TGTTATTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTAGCGGCCTTCTGGCAAAACACGCACAGAATTTTGAGCAGTTTCAAAGAGTGCGGGAGAAAATTGATCGTACAACACGAGCAGCCTCTGAGTACAAATGCATAAAGAGGACTCAGTATTGATTTCTGTTCACCAATATTCCAGGCTGCTTGTAGCTTTTCCTTTTGTAACTTTAAAATTACCACAGGATTCAACAATTTGTTTGAATGCTTTATAATCAAACCTTTCACAGTTTCCACAAAGCACTTGTGGAAGCAGAAAAAAGATGCCAAAATAATGGCGATCTCTTCGGTAAGTTTAAAGTCACCAACAATATTGATGTTGACTTTCTCTTTTGGGTTATTTCAAGAAGGTTGTCATTAGACCTTCGGAACCTTCTCCAACAACACCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +$1-+&%*/66;;:C994@AB>1.''&&+-7'(3DMIDGCB><93<3420/567;8:>=;>>?C?>>:=>9<4>7>A>@A@@7&&+9:D93>>BEC@A@6;85:67BBAACG>:;56/7C@5<.($/2,:47978:5156*8%.>32=>27A@?D>=A@;;09;:>=::?8611-'()$%.,1222>565@@?9;8737;:?@>>>=89;114<;5+,10+0,,+)*(/4(&&&-3:;47/4774$%;678<@=IFAD=@GH;@A?C3#$3054>@?CEE>55.'(&'.:=>@?<91&%%+:<:KKEBE8;97)$&$%,9::0D78/?A0=:@B=<8:;CBJA@B>6@C?D:=DCF88BFF>I4;@ABD@@CB@HF:?DA?CA<67;HBFGEDBDEEC:A:;CHD@@6+$8;).BC>>9988://3C6:><)83??D?EEC99:<+,$.+//AB@@/2*)99B1);>@9;>?GA>JEMLC7$%7;BBGE@B@:11;>45;>>A;=;$((&()*.2:9<@@B:@>DG=?97862'(121:???BA?72;A@>>;BBEBD;CAE??@9>884.=369<:<=<>99<700+0$*()*+)-%%&&'%((' +@SRR11410539.874918 874918/1 +TATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCCAGCAACTGTTTGGACCCTAAAGTCTACTAATTTGGTTAAAAACAAATGTGTCAATTTCAACTTCAATGGTTTGCTGCAGGCACAGGTGTTCTTGCAGGTCTAACAAAAAGTTTCTGCCTTTCCAGCAATTTGGCAGAGACATTGCTGACGCTACTGATGCTGTCCGTGATCCTGAACGCGAGATTCTTGACATTACACCATGTTCTTTTGGTGGTGTCGGTGTTATAACACCAGGGAACAAATACTTCAACCAGGTTGCTGTTCTTTATCAGGGTGTTAACTGCACAGAAGTCCCTGTTGCTATTATTCATGCAGATCAACTTACTCCTACTTGGCGTGTTTATTCTACCTAGTTCTAATGTTTTCAAACACGTGCGAGGCTGTTTAATAGGGGCTGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +#%&(4:8=D3:3I<4/9??@>@>IEF:>>55?@BAGH8;6:3.51567::;4137-455691:+;2<633>AAA<3.0=48&&4?9/;@@=?FCGIIN<>EH138>==AAI;@9@=C;<:?<>88697<1179;DA7'&&$#$,>?5/,94?;112/0(*+'4<;:=9'+8%>352@I?>;9;**(A:=B22,-&%&.64BBFCJDB@:45:7BA>67.%%%+3((*+:9A<>;DEDF?BEB4H>??>@BD=GDG=68<./387>.5)1)*(59EE0@@=;/.27887=7CE))1%%)3;(,44=?<==16:5<<<9417771*$)$%DG699;;;BCCRAFHKIBF@?I?711BB0AF9A5?G@),)/A<;;96<41EF==7ADD;GH@AA;-( +@SRR11410539.1808574 1808574/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAACAGCGACAGCACCTACAGTATTCTTTGCTATAGTAGTCGGCATAGATGCTTTAATTCTAGAATTTGTACTTCTAGTAAAAGTACACAATTGTAGCAATAAAGTAAAGAAATAAGGCATATATAATTAGTACAAACACGGTTTAAACACCGTGTAACTATGTTAGTAGTTGTACTAACAACTTTTGTTAAGAAAAGGCTTAGCATAATTAGCTATAGTACATCCCAAGGGACACTATTAACAGCAACTAAACCATGAGTAGCAAGGGTTTCAAACCTAATACTCTAGATAATTCATTAGGTTTCTTAATAGTAAGACCAGAATTGTCTACATAAACGGCGCCATTAGATCTGTGTGGCCAACCTCTTCTGTAATTTTTAAACTATTATTTGCTGGTTTAAGTATAATGTCTCCTACAACTTCGGTAGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +)&((3430008?K5:3=8@B97><:8%%-3.EGCBHG8748:8967+++-)&)%02/-6:>@<:8:957?<;;@HHMGHGEEDGAB2)069=C=A88/,18<>=>@<6(5'356:C?CC?@AC9259AE;-6:8<<7??;B9536656))*-2?DJ=':;8.-.,+)()*&5=4544./?88696132<>:<><;/..(879ED23;6?<;@@BG:>01/,22'(:<@DCC?C0?'9/?)89(/5AA<>9A?=89<;=@==?1:=??85:-&45;9:'/$*%$%&,,1,2&6;>>>BF?B==:;;:C9<@?:,58:5BD?7>2:&*AD=78.1-2-/'46GBECC=?:8@=DAB?B@4833877ABEEBBA;2), +@SRR11410539.1630004 1630004/1 +GTTTTCTTCGTTCCGTGTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAAAATGTATAACTCTCATATTATAGGGTACAGCTAATGTTAATGTGTTTAAATATTGACACAGTTGAGTATATTTTTGCGACATTCATCATTATGCCTTTAGGTAATGTTGCACTATCACCGCAATTTTGAAGGTCACACTTTCACAATAGCATTCTTTGCATTTGTAAAGATTAGGCATATAACACCCGGTTGCCACGCCCACGACCTAGATTGTAATTTTGGGTAAAATGTTTCCTACATGGCCATCTTACACCAAGCATAAATGAAATTTCTGTATAGTCAATAGTCACTTTGACAACCTTAGAAACTACAGATAAATCTTAGGGATTTTATTATTTCAACAAAATCATCAAGTAATAAATCAATAACAGAACACACACTTAGATGAGAACCTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGGTAACCTTAGCAATACGT ++ +&())'%%466<''(..%;115+++*2102:4262454.5:::;73%(%/569=>A>;>@=<=?77&);BABCC??E@ADDEIFFHEA@D@J?9A<<2279?EAGCHFC9076<:95*C>=7<3(-'55673--./5712>>.230),-+'%&%%%-&,+022=46.4007//0-.(*06.4+7<<=?DCHCEDEE=07++%;98900+0//-)69;8953//==AB<47.---$$97,+24822:>?=:=:7890$111-8;B?878168.*-/6EFFD992-9%'''&',,.1)8=><44+>';=>A%:,;:<<::..$%%)599BB;>>?A75FE?CEHGB<>8A@=>??;4:89950($&&+2+471571)'(%& +@SRR11410539.2310793 2310793/1 +CGATGCGCTTCGTTCCACGTACTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTCACCAGCTGTCCAACCTGAAAGAAAGATCACCAGGTCAAAGTAACTCATGCAAAGTAAGTTGGGCTCTAGTGATGTTAATACCTGGCAAATCCAATGGTTCTAAAGCCAGCTTCAATGAGGGAGATCACGCACTAAGTCTCATTGTGCTTAGAATATATTTTAAAAAATAACCATCAATATTCTTAAACACAAATTCCCTCAGATTTTAAATGCCCTGTTTTCCTTCAAGGTCCATAAGAAAGAAAGAAACTGAGACATATTCAAAGTGCAATTATTCGCGCAGAATAATCTGAACTCACTTTCCGTAGCTTTTGTTGTTTTGTGTTAATAAGCAAAAATGGATATTATAAAATTAGGTGCTATTCAGTTCGTTTATCGTCATCTGTTTACCTTCTTAATAAT ++ +/'&$$$$#$&#&.0&-%*%+$$-#$-9<<<>74-/.29:727599,,&%*0566)-)-334573310/362313,-:;,4.2%-9)&%,('$$%%%&,()(&$$##%'$'&%'13/.7&&)2.$%&**8===>=AGBGD7861&'+122589&&9=71.1@2:.9;5120$*-20*$$%&%/34233454.-(+=8/0''$$#$$'&=.255;=;@:<2<84;9=?=6=;>AB8988;10,657:97/0'&''*/..0%..,%&%$%%&%()*,'44/2557@=9;A9;12+3(*7./--*2.%$(('$'&$$$$(9;>8;ED,3ABC;IFG??<:....,-$$0./3,)('/1554:68?;BC697EB/1-')/00+,#*?@;??;470&%2+$$-.,)(*$%$'$%$$(.%)'/.%&&0*$)&'/.($50,45+*)'&'%$&(('%%' +@SRR11410539.851512 851512/1 +GTTGTACTTCGTTCAATTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTTGTCCAACTTAGGGTCAATTTCTGTACAAACAACACCATCAATTTATAAGTAACTGGTTTTATGGTTGTTGTGTAACTGTTTTCTTTGTAGAAAACATCCGTAATAGGACTGCTACTGTATTCTAGAAGGGACTTTGTAAGTAAAGCACCGTCTATGCAATACAAAGTATTTAGAGAGTTATATGTTTATAGTGACCACACTGGTAATTACCAGTGTACTCACTAACACAAGTAAACACTGCCATGCTTAAGTTCATACTGAGCAGGTGGTGCTGACATCATAACAAAGGTGACTCCTGTTGTACTAGATATTTTGTAGCTTGTTTACCACGCATTACCAAGGTATCTGAACACCTTTCTTAAATTGTTCATAAGAAAGTGTGCCCATGTATAACAGCTTAGGTGCTGTCGATTCCGTTTGTGAACTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +,3434/;>A>:E;?(((5/50686:/>B77.CA@@A=8<<>ABA==9;AA=6748@53:6426-=CEDD;**<>?0005-7/%>;<>6846HE?@A5:/08:<>?AMFGE34AC662/:56665=5'*2::?@<91?5?;?FID99>45..+/*4+&'##%&)-;?:B6843:76&&7=>9>735,$##*-3516'(&+08@A;:?<0&3//?>==@BCE==78=02/18>AE>CE95@GA@/;555C=67**)*&&&&()54<;:000242?--%-*+322;9.//@<>>206=88?5A5@9:7?<*%:F=>BE<&$7''+(%?;=?@284<3--//7:BA==FBHCB?CD?A>/=66)8%&&&/14@=<:9872149:<4;:8%($$$#&*+:=>A<>;9:=:9:9129876;<>?7./ +@SRR11410539.1789191 1789191/1 +GCGCATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACGGAGCGACTACAAACGGAATCGACAGCACCTCACAACTTGCGTGTGGAGGTTAATGTTGTCTACTGTTGTAAACACCTTAATAGTCCTCACTTCTCTCAAAGGAAGAAGTGTCTTAAGATTGTCAAAGGTGATAACTTCACCATCTAGGTGGAATGTGGTAGGATTACTAGTGTAATATACTTTTATCACCTCTCTTAAGAAATTCTATACCTAGTTGTGTAGATTGTCCAGAATGGACCAAACCAGCAAGTGAGATGGTTTCAATAAAATGTTCTTCAGGTGTTTAAAAGAAGAAGTAAGATAACAAATTATACGCTGTAACAGCATCAGGTGAAGAAACAGAAACTGTAGCTGAGCTTTGAGAGATCTCATATACCGAGCAGCTTCTTCCAAAATTAGGTGCTGTCGATTCCGTTTGTAGTCATCTGTTTAACACCAACAACGCT ++ +##"##&*5179<9:G<;99AFD@>==;?68<...DCBAA73%)%'0332,,(0/(0(*'-26>C?B>9:@EFB6@=D@BD??1-B2?=C=BC=;;4<0,,.6;;:=>BG:25?;/&)//*2/1>;58@A?;57548>C>:8?@D@/9,=46/*$&%&$$)**3;>A899,BAG>4+375.0344709:980<;82-,()-/182&&8?8:73%+2*)$%$,/60/022;@/34571><8@?A>9<:D=???<;4@=>@>>;6?782697.426-17-=F=9972*)&'.%+--/?=;&,/.23626120000812,:(0059DB28A=6;:<;>>BA?A5,8<::8,09=:+,.4687--&#+*++&&%&(*+*-*+*##% +@SRR11410539.556256 556256/1 +GTTATTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCAAACAGCACCTCATGAAGCATCACGGTCAAATTCAGATTTAGCCATTCAAAGACTTCTTCCAACTTTTTAAGAACAACTTCAGAATCACACATTAACCAACAACCTGCTCGCAAGCTTCTTGAGCAGTAGCAAAAACACATATGATGGAAGGGAACTAAACTCTGAGGCTATAGCTTGTAAGGTTGCCCTGTTGTCCAGCATTTCTTCACAAAGCTTGTTTATGTCTACAGCACCCTGCATGGAAAGCAAAACAAGAAAGTAGTGAAACCATTTTTCAAAGGCTTCAGTAGTATCTTTAGCTAGAGAATGTCATTGTGTAACTGGACACATTGAGCCCACAATTTAGATGATGATTCTACTCTGAGTTGTTGCGAAGCGAGTAAGACTACTGATGTGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACCCAATACGTAACT ++ +(-/11438:;64714*<>>=:6:66844<43==CA>A7@?CA?88<8559:1/%'&(03'*'776?>88=>1)+$#%*<9<==993?6::?4362<89680/.9G:@AB+7:&&*&&2%(,.%%'++1;>2=FE@@?A6:;<74?57568;EF;<<>48681><7.:,5667872+?>A>CA64//0&'&-1-2057@?@4(02?BA9AIIBEHDPFC=EFHA4$%6AA?71.2<>=GD><;FGN?+6FG0.->B*:27?A8?7):;H=>9:6AC2=338;?A>?7,,5.-5331>>=<@CC>EEI@HC;9,9;:=F9=:6DCCA>;=:A?E,+A<;<4135;<:@8926232/)))-,..0*/(('& +@SRR11410539.350912 350912/1 +GTTGTCTTCGTTCGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCCTACCTCCCTTTGTTGTGTTGTAGTAAGCTAACGCATTGTCATCCAGTGCAAGCAGTTTGTGTAGTACCGGCAGCACAAGACATCTATTCGTAGTGCAACAGGACTAAACTCATTATTCTGTAATTTGACAGCAGAATTGGCCCTTAAAGCTGTTACAATAAGAGGCCATGCTAAATTAGGTGAATTGTCCATACTAATTTCACTAAGTTGAACAATTTTACTATCTGCATCTACAACCTGTTGGATTTCCCACAATGCTGATGCATAAGTAAATGTTATTGTACCATCACACGTATTTTTATATGTATTATAGTCTGGTATGACAACCATTAGTTTTGGCTGCTGTTGTAAGAGGTATTATGTTCAAGGAACACAACCATCTCTTACTGCTTTGGTCACTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAT ++ +),+&'%$179B;:3?=B@CCJKI?=B114>CDKNJ5@5<6;918A?:A8H3BA7;B99B:497<=669A?EF>:;DD54420--=7<>ACBHDDFB=?A$$>4?FCC@85>7=EEG5>?>A?=:88631.:8995746?<=?1((*08:?AA=D>?<:==6<=BE4??;?BB7>??853+,+.FEI<8C6=28<9+3/01./3.5==::??=961+--*+-/:///489:>;77A=660=JA=:9/022?8787.7)..*263A?AG?=:6>63333%%&(5849/>?A33*>CEE@@AEDFE@?/'#';;48@34<6+++///;=50?<9/@AGBBBIG;1++*+&&8B=?=DBEKD<@=?=8/25:;8@CIHAGIJ<5//GDB@BDHE??76:97ACHA228<;?A1;<.)&((&%%%#&%%$)56<=:679254<;B**66;=8<<9:AC2<>C<:3/'311449''%% +@SRR11410539.458452 458452/1 +TGATGTACTTCGTTCCAGTTACATGTTGCTAAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGCACAGGTGACAATTTATTCTGACAATTTCTAAGCACAGGTTGAGATAAGTTAACAATTCCCAGCAATCTCTAGAAACTCTACACCTTCCTTAAACTTCTCTTCAAACCAATCAAGGACGGGTTTGAGTTTTTCGCAAAACGTTACAAAAAATGTTAGTTGCTTCACTGCGAAGTCAACTGAACAACACCACCTGTAATGCTGATGACCATTACAACTAGATTGTTAGTAGCCAAATCAGATGAACATCATAGCATCAATAGTCTAAGTGAATACTGTAAGGGTGTTCCATCTAGTATTGTTATGGCGCATTCTATTAAAGCACGCACGAAGTTGAGCAGTTTCAAGGTGCGGGAGAAGGTGGTGTTACGACCTGCTAGGCGACCTCCTGATGGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTCCAAACATAGCAATACGTAAC ++ +#&$'%$#()+((,0%,&*,,%'%%%,-)(*/.'%0'(-./1026931/-56==3*/23>>>CE60CFIBBFHEE;072?@66>4739-##$'%$+(..(+3)$$&*34545=E<557?7..-:;55;7776$(&'&0-*#$%&#%$34497.=<1<43/.9;=AMPC=><9*=>H:0:004:=..4AKKB<;C@B>;--49:;167'%*+:8?454*+.)*&+%&,*5C=7;6;:?/5-%'#%#%%$$)0+&1/**)$$$(&&"$&$#(&''%*5.SI>@=DBF==<:261;@9076$'$%'%$$*&'%%%%/+,()& +@SRR11410539.1192032 1192032/1 +CAGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTAAGTGGAATCGACAGCACCTCATCAGGAATGCACAACTGCTTATGCTAATAGTGTTTTTAACATTTGTCAAGCTGTCACGGCCAATGTTAATGCACTTTATCTACTGATAGTAACAAAATTGCCGATAAGTATGTCCGCAATTTAAACACCAGACTTTATGAGAGTGTCTCTATAGAAATAGAGATGTTGACACGAGCTTTGTGAATGAGTTTACGCATATTTTGCGTAAGCATTTCTCAATGATACTCTCTGACGATGCTGTTGTGTGTTTCAATAGCACTTATGCATCTCAAGGTCTAGTGGCTAGCATAAAGAACTTTAAGTCAGTTCTTTATTATCAAACAATGTTTTATGTCTGAAGCAAAATGTTGGACTGAGACTGACCTTACTAAAAGGACCTCATGAATTTGCTCTCAACAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTCTTTATGTATAA ++ +%$&%&32566<@IG969:<8@9410.07;4548?<::.)$$%%)'&%$%$'&('+59;442DCA==@<.,8254(%*)1->88@F>=ABA@C@EAD?C?>BDB34?B@:;<<<6=>600.65-&,0./4,/>D;<>@?::C<=;EE;<;>D33-/+/4-//.3'5,/,67967:AB(7>EF?BEFCH:B5EIC36.)&*20488-*(+-,.<=>A8CHFI???JFJC:=*3:@CA@IH;77946$5;==>91?A@9++.(3=>?B60?A=?F;=?7=>6;57>:>3*-)33,=>95?@C@=@3/<36/4:=69C;A:8;0-@1:9A=;>@?>(-JB<=?<43./.((7(%*%%596?=7)':?>>CB=<569CEG:;G?9?2104,*((15$.1,5,:;;8<:3$'+-130/3'&,2'''%##%''&$% +@SRR11410539.70594 70594/1 +CAGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACGGCACCTAGCTCATAAACTCAGGTTCCCAATACCTTGAAGTGTTATCATTAGTAAGCATAACAGAATACATGTCTAACATGTGTCCTGTTAACTCATCATGTAGCTTTCTTATGTATTGTAAGTACAAATGAAAGACATCCCAGCATACTCCTGATTAGGATGTTTATTAAGTGGGTAGCATCTATAGCTAAAGACACGAACCGTTCAAATCATAAGTGTACCATCTGTTTTGATATCATCTACAAAACAGCTACGGCCCTAGGATTCTTGATGGATCTGGGTAAAGGGAAGGTGCACATAATCATCACCCTGTTTAACTAATTGTATGTTTGAGAGCCAAAATTCATGAGGTCCTTTAGTAAGGTCAGTCCAACATTTTGCTAGGCTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +)%$%(-*4409;E8402;>B>;GGFJ8DB$%309A@A(4161<0//69:;<<=BFHB>?9::+0/>><3<,1(7%+,-4803((/:<8:CF;21383283.67*@?CBB:;8/%0')7:8988E?>:AB@@0/0/;3)66.+-/3334')'*)).<9-';'2(;;<::>>27887?9FAEE?>>>::B?@@935>:7>:;))>=@B@=9<:2*-%&-**+''),6>?>:38<8>3BE8BCB@5&&,-.2=28+-*&$'(01,<9??9<;79))345,(),233/:<<76=>A:+5'*%$&(,B=>;>485=@>>GE?B@CA:<9.,0/)*('-(2,3+)%%'3/24201-++//-,=7<=A:3/5$$$(#&,$$79::7+0('1==;?885()-'(6--90?C?>82837/.&100?EDD>FGM<2150-)#$&%,0-@<==@@:=>>;BACG=A@A=@+3700', +@SRR11410539.364789 364789/1 +TGATGTACTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACCTGAAGAAGTCAACGAGATGAAACATCTGTTGTCACTTACTGTACAAGCAAAGCATGTGTCACTGCTACTGGAATGGTCTGTGTTTAATTTATAGTTGCCAATCCTGTAGCGACTGTATGCAACAAAACCTGAGTCACCTGCTACACGCTGCGAAGCTCCCAATTTGTAATAAGAAAGCGTTCGTGATGTAGCAACAGTGATTTCTTTAGGCAGGTCCTTGATGTCACAGCGTCTAGATGGTGTCCAGCAATACGAAGATGTCCACGAAGATCACAGCTCCGATTACGAGTTCACTTTCTAGAAGGGTCTGGTCAGAATAGTGCCATGGAGTGGCACGTTGAGAAGAATGTTAGTTTCTGGATTGAATGACCACATGGAACGCATTGCAGGTGCTGTCGATTCGTTTATGTAGTCGTCTGTTTAACCTGTAATACGCT ++ +',+&'+&9<=;>F6<5=FEA@=FHDFAB08)>JEDG?/+1+:?==91;<=075;9@;<>A>:=:?A>D@66253/'('::A55@:2;AFHED=+,''('%&*,C@BGLF@3DGFHA;?8=;>=2386;+,=DE=>@@<,-;4CB;:FCCAB@=?CFI<;45@1B@=CE998AHBHGG?B>:D>>?7B@>=AA-%>+54<;.011++:?2>?4--9786(/(068;85833%49=:746AB0;:2:>8/5)54.5;:;:44%$.0=;B=93,B?E8;:>@GFBA<<07$:9=?A>?>BAA?:@DEE<>;418921*$/$%)$3/27;;;A=8C@=?(?9LI/&&)+0.:?==A??BBB88&(&&$01,,1$#% +@SRR11410539.1279441 1279441/1 +CATTGTACTTCGTTCAGTTACATTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTCACAACTTGCGTGTGGAGGTTAATGTTGTCTACTGTTGTAAACACCTTAATAGTCCTCACTTCTCTCAAAGAAGAATGTCTTAAGATTGTCAAAGGTAATGCTTCACCATCTAGGTGGAATGTGGTAGGATTACTAGTGTAATATACACTTTTATCACCTCTCTTAAGAAATTCTATACCTAGTTGTGTAGATTGTCCAGAATAGGACCAATCTTTATAGGAACCAGCAAGTGAGATGGTTTCAATAAAATGTTCTTCAGGTGTTTTAGAAGAAGAAGTAAGATAACCATTATACGCTATAACAGCATCAGGTGAAGAAACAGAAACTGTAGCTGGCACTTTGAGAGATCTCATATACCGAGCAGCTTCTTCCAAATTGCTGTCGATTCCGTTTGTAGTCGTCTATTGGCAACAGCAGCCCGTAA ++ +&&,.78899=>=G9;76;<:9(')66=>?EB@1AHCJKH>78<,56334567-*$'*.34?B>:A>:07=93:77.//7>69:;;:(ABBBEH>??@==>B@AD:;=%$348;@@??=?ABCA78>-).A=??G:B@BC;<>48965,+52++96<@@EB?=BDAAB.4@7:+,$251164983BA/A=A;:-%-687++2>''5@/?D9@9CB5>::58AECE9@9B@<81D(=.//9=:7EC=@EH?C>AB=@D766@97456/8DDFJDG@E9C2994253.3670CC00,3536?;:;+)(#68<:?;B861(*)?CBL5CA:<&&C><;>=2709<565)6675:01+),<>=?8?@:213?ADHGIDLD=EA,.('&&+$)-+5;>:<>8:5:9?27:999711(%%)%%###%%&&(##&&#&$& +@SRR11410539.440169 440169/1 +GTTGTACTTCGTTCAGTTACGGCAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCTTGGTACACGGAACGTTCTGAAGCTATGAATTGCAGACACCTTTTGAAATTAAATTAGCAAGAAATTTGACACCTTCAATGAGAATGTCCAAATTTTTGTATTTCCCTTAAATTCCATAATCAAGACTATTCAACCAAGGGTTGAGAAGAAAAAGCTTGATGGCTTTATGGGTAGAATTCGATCTGTCTATCCAGTGCATGCAAATGAATGCAACCAAATGTGCTTTTCAACTCTCATGAAGTGTGATCATTGTGGTGAAACTTCATGGCAGACGGGCGATTTTGTTAAAGCCACTTGCGAATTTTAGCGCGAGAATTTGACTAAAGAAGGTGCCACTACTTGTGAAGTGCTGATTCCGTTTGTAGTCGTCCTGTTTAACCTTAGCAATACGTA ++ +$#$&*)''943:/525;906(*'')6))38(=:>>>7'423;6;DC>>09?DAAHD><=CAAE@:865A:?@C9>KLMB=@@9;8;)><5:C=D>JAA>=JEI?@JDG<841103)*:;<%97@?'6EBAAJGEAG:;CECB?0:768@36335EDBA06<;>>=8BBDDCC67?4CBACB)=:';;GA5'%&&:>D=A;;<48/128,-(+-7:<:@=ADC@''/2$/(-&*&(,.8@BEJ07E99:CDDG887+0*%%)19;B<86BBCDE@D?@DEC<<,-.73@;;DD=CAE>>EG?;?B8A:;<>><1(/4+*.-'+2061@?99BC,:830=A??=53344440+%%$7BBA>60,->@@PNMEFF?584''15;DEC//7:64/,1//+&*#$$ +@SRR11410539.2362438 2362438/1 +GGTGTGCTGATTCAGTTACGTATTACTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTTCTGCTGCTCTTCAACCTGAAGAAGAGCAAGAAGAAGATTGTTCAAATGATGATAGTCAACAAACTGTTGGTCAACAAGACAGCAGTGAGGACAATCGACAACCACTATTGACAATTGTTGGTTCAACTCTCAATTGAGATGGAACTTACGCAGTTGTTCAGACTATTGGTGAATAGTTTTGGTAGTTATTTAAAACTTACTGACAATGTATACATTAAAAATGCAGACATTGTGGAAGAAGCGTAAAAAGGTAAAACCAACAGTGGTTGTTAATGCAGCCAATGTTTACCTTAACATGGAGGAGAGATGATGCAGGAGCCTTAAATAAGGCTACTAATACCATGCAAGTTA ++ +$%+%$$$)('%)&$%$,5/*-+,.'0-%&3DI@57*<7;EDFH)8**AI;>>950(80<&$',-+&$''7<;E<=E=7.;/.3=@CBDFFC1575)*1/110+&664509,-887/.,+&$''&'&%#*-'($)*#%#&&.,%*=<9%&$$$-<)*%'$*-18685-#%&#$$)(-)-$52&,.3;>7;:#&,&&%(#%)/0-$%((34/'&)1ACHE>EB?;:?>99=@@;>AH67>@>CFEGJ8:=??;-;6-'$0783-$-7:?@=973&&21?ED??ABA??>9;=6''014-/-((($$$&1%%+,0:51+ +@SRR11410539.1873717 1873717/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACCACAACGGAATCGACAGCACCTAATAACGGTCAAAGAGTTTAACCTCTGCCAGTGAAGTCATATTTTAACAAATCCCATAATGTAAGGCTTTGTTAAGTCAGTGTCAACATGTGACTCTGCAGTTAAAGCCCTGGTCAAGTTCAATATAAACATTAGCAATGAATAATAAGAATCTACAACAGGAACTCCACTACCTGGCGTGGTTTGTATGAAATCACGAAATCATACCAGTTACAGTGGATCTTGATTATCTAATGTCAGGTACACCAACAATACCAGCATTTCGCGTGGCATCAAAATTTGTACTGTTTTTAACAAGCTTGGCATTACACGTTCACCTAAGTTGGCGTATACGCGTAATATATCTGGGTTTTCTACGATCATACCAGTCCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAA ++ +#&,,:B@89;)$?5@9:KHB=71/-.-74@A*EIC9;:A:;?=30+&$'%&(15/:;;:44023/8)C44/%&85:68A9()-=03%'(()(0'$'-$%;<=:C>E:77?>@9..4//,0)*&%1?B<@DEC0<5699+*/3512:*1@.*@?><:56371/62;.-':7-8;8;:937+/33((5+2%..+*%$%#)&%&-&-=@<33<>;>(39:90@=?-4;63%)+,1,,3832EC:@20,-5?96)#$%%&&)*%&&$.&*4-3#+,,8;?=?9-.),*/$,7<=:A65326<921%%&&5:CE@C0)(0(*-*/2$')..3>;?>?ED=<=<=,-968->@?9=1&&)'$&88>;C;=)954+56.8B@?2&*5DFBA8854*345-')=BBF:1($%)+.9//035CB7797/66<*<<>::85>?)38?B;/.--=@2,A.1,-*9<>B?>9:80.(',)+$) +@SRR11410539.1816026 1816026/1 +CAGTGGCGCTTCGTTCAGTTACGTATTTACTAAGTTAAACAGACGACTAAACGGAATCCGGCAGCACCTAGCACATCACTGCACGCTTTGCGATACATTTCTTTGTTAACAAAAGGTGCACAGCGCAGCTTCTTCAAAGTACTAAAGGAAACACCTTTAAAGAGACTACACGTCTCTTTAAGAGTAATTACTAAAGAACCAATAGAAATGCTTTGTGGAAATACAAATGATATAAGCAATTATTATCAGAAAGGTACTAAAGGTGTGAACATAACCATCCACTGAATATGTGTAAAAACATCATTAGTAAGATAAATGTCAAGTACAAGTAAATAACAGAATAAACACCAGGTAAGAATAGAGTAAACTTGGTGTTAAACAGAGTACAGTGAATGACACATAAGGAATAGTAAAGTATTAAGGCAACTACATGACTGTATTCTGCTGTGCTGTCGATTCCGTTTGTAGTCTGTTTAACCTTAGCAATACGTAAC ++ +,%/.%&()'''+9G=//+168)%%%$&)%1/$$+&/ADC999<@2/**-.,+1524''>01&..1/4*4/:;:@4,,(*.%%$'&356/%%&%49??BDCBB<0*-1//9:+-/*,*,+())+,,-&''4><=3237:>AE5FE?%&,&4CCCCFB=BHO;<=;<77.4+.)C@-%04881$/+72*/>@,+/<-3*,4;9521'-7;:77=872*%$&:<3066:8:..2-6533&73$'<<;;?)++97@454EEICB62)9+8E==AG@A5845?A1110-&$%%)501,##'''77===@;.+)))%%&&&;44=><<;,(47@D4B>45:77:32+031243<@AHG988::-%%*+9>;;GB:44%+%&4%%$$))984&-$ +@SRR11410539.1656368 1656368/1 +CGGTAATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCGGAGTCGACAGCACCTGGCACATGGCTTTGAGTTGACATCTATGAAATTATTTTGTGAGAAATAGGACTGGGCACCTGTTGTCTATGTGATAGACGTGCCACATGCTTTTTCCACTGCTTCAGACGCGTAACCTGTTGGCATCATTCTATTGGACTGATTACGTCCTGTCCGTTTATGGGTCAGTGTTCAGCAATGGGGTTTTACAGGTAACCTACAAAGCAACCATGATCTGTATTGTCAAGTCCATGGTAATGCACATGTAGCTAGTTGTGTCTAATCATGACTAGGTGTCTAGCTGTCCACGAGTGCTTTGTTAAGCGTGTTGACTGGACTATTGAATATCCTATATTGGTGACTGAACTGAAGATTAATGCGGCTTGTAGAAAGGTTCAGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAACTTCGTA ++ +.$''#'%%78:=>I2/)>497A=BB>A22;%&8@B@?@'/,.*-<><;E=;8%3&('$014+19-26AA?<76<:CJAC779<<9=;73.3//8=EFFE=:87&*+<9>8;80-$&&&'//81?A;=ABD?@@@@>=?GC@95>@<;9;;BA?7:4=EC334*$&(&$+%&&&)*-;?A;98;,8%-@CB><<>C8933./16/-'-&,7779;(82030&.8@8ACA????:1(4;8=5>A:9:E640*(=57;;@<<423<<GHDE;=::=88<57<;?4482/).$)*.64;*6++5:?D>C@>587::*1(3BFE=70.=8%?FCB79/7:>?@DE<>31)),/5037>@H?;=BB==23*+21?><9B:<:ED780??0.?4;%$$$###%&&,'45.56602.BA66?A12@A7BC99:ADJHED=1NJ==EEI87?;94248/2-<70,(>?C>;/+7*<D;<25?F@DC@BC>@@4,1'%%*=BABGEGGDCFEEHB9B:;=D=<@LF=%$-12041;BEAEDB<@A/364>A560E>9>A9?<>JBFJAGF=8(:69<@870>5=/===AA@B*8177/$$(;=?C?GC7--/0''6AA,)9ACIGCLIDD>;243;/;9<:9A;@GEF=79;BCH>@A@9;%%8;8;3/#%+')&%&%&)////954**% +@SRR11410539.1357596 1357596/1 +TAGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGATCGACAACACCTAAAGACCATTGAGTACTCTGGACTAAAACTAAAAGTGAAGTCAAAATTGTGAGTAACAACCAGTGGTGTGTACCCTTGATTCTTTTCACTGCACTTTGGAAAGTAACACCTGAGCATTGTCTAACAACATCAAAGGTGTAAATTCATCTTCTAATAAAGCACTACCCAATATGGTACGTCCATTCATACCATTTTGCAGTAATTCTTTTAATGAAGCACATATCTAAAACGGCAATTCCAGTTTGAGCAGAAAGAGGTCCTAGTATGTCAACATGGTCTTGTGTTAGAGGTTCATAATTGTACTTCATAGCCACAAGGTTAAAGTCATTAGAGTTGTGGTAAATCGATTGAGAAACCACCTGTCTCCATTTATAACAGCGGCGTACAACCAAGCTAAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +#'$$%,*89:98H?=;;GGA?>AACC;D@AA,AFDBEH3A1?/879A@=@A8-.)*29=:9%%034)6BD;=D=@AA3+(889954@<>C@ABHGI>9EI?44AE<386>II;FADB?A-:?>?F:;99:9956<7423999''(1316=BEPLDF@DG@E>@A>&'*(&%#&%-2321$$*;*6>1+B/66>@AA4.5AC:+BCB@14-;>?@;<=1;0++;>?BCH?*+*):?@=>8B?I;CEEBCCAB.ECD85>:>?C?A>BFCC>C==A9DD@87,'&&.9-.7>@:;BEA=4@??:=>@@79GF?:=0.*($4E8<566;<9:<=>@,809,3.=44;DJIFIC@?G998:/*6*0B<9>@=A?B@9:@:=?@@F=:>>.*6;+4?:ACBCC.A456CBKL.2?E<B?>LE-868AD4:D>9=2,@3CFJD<2-../9;=>955=85*)%% +@SRR11410539.911293 911293/1 +CAGTATGCTTCATTTCAGTTGCGGTATTGCTAAGGTTAAACGGGCGACTACAAACGGAATCGACAGCACCTGGCAGCATCCTGGCAAAGCACAGAAAGATAATACAGTTGAATTGGCAGGCACTTCTGTTGCATTACCAGCTTAGACGTACTGTGGCAGCTAAACTACCAAGTACCATACCTCTATTTAGGTTGTTTAATCCTTTAATAAAGTATACAAATACTTCACTTGGACCTTTAAAAGGGTGAAACTATATACATTTACAGGGGTGGTTCAGTTCTGTATAGATAGTACCAGTTCCATGCTCTCTTAGGGAATCTAGCACATTTCAAATCCTGTAATCGGATAACGATGCCATTACAAGGCCTACCTCCCTTTGTTGTGTTGTAGTAAGCTGTACATTGGCATCATCCAGTGCCAAGCAGTTTGTGTAGGCCACCGGCATACAAGACATCATCGTAGGTGCTATCGATTCAGTTTCTAGTCTGTTTAAACATAACAATGCCGCTAAC ++ +#%'(*&&-..,&*/3(-:14+0%($%+,*)-$$+=<:@C;8*..*87@@<7??5?584;;>:;5224/-'&'(,&9@=))*0.10131)A?800:?).C@8<:92/=340++'&'(*&3:98=@;A<:?5-1''(&,.**&&&(/(+3:=;:.2,2*(/07?A;22606<=2FA??0,-22+/=4@??8;=65&==;>B?BEEH;886.1.+<3)%#+-(&'$&)3*).+%)*#$$)),-'%'/+))(($$&&%$##$%#%'"#$%'')/).*(44:C16))8925-9--*9<24>9C?.,*%$(,.('0359?<>@9;-(+#=?<==;,,2-&%$((0'+'*$$$$%$%('$#%#'#'##'$((++45;77?D=GI=BBCHE89<5*+*+-&&$&$$(*+,(<>;%%.'&,&&0&'&*-(;>D/5-'*'%&&%%'#$2%$))1245%.11/3,&&&'*$$#&%3:??E*-%&##%)$%&+8%%**)/2+.$%$$')*)'(($$+)-, +@SRR11410539.628809 628809/1 +CGATGTGCTTCGTTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCGGTAATACAAGGAGCTGGTGGCCATAGTTACAGCGCCGATCTAAAGTCATTTGGCTTAGGCGACAAATGGCACTGATCCTTATGAAGATTTTCAAAGAAAAACTGGAACACTAAACATAGCAGTGGTGTTACCGTGAACTCATGCGTGAGCTTAACGGAGGGGCATACACTCGCTATGTCGATAACAACTTCTGTGGCCCTGATGGCTACCCTCTTGAGTGCATTAAAAGACCTTCTAGCACGTGCTGGTAAGCTTCATGCACTTTGTCCGAACAACTGGACTTTATTGACACTAAGGGTGTATACTGCTGCCCGTGAACATGACATGAAATTGCTTGGTACACGGAACGTTCTGAAAAGAGCTATGAATTGCAGACACCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAA ++ +)$$%'0.9GE@C69)))'..0,))696;#'&79;DD:83;=<=DD:;>=3(+%*+'1+7>AABDCDA?>:6530&-&-:;;'(7:-*;79<@75-680CDC>:52<-&8?=?=D71)2499?<>;>;9CC:????<<<<:;A9?AA5-:><78C6>FCHG?GGIHEIKJDB>?<=23>>=@BA)&78780&--/+#$&%%%&%125:3ABEH?5678<@E9ICDIRHD;K8@568C4*-HIHKH*==>=A.@<94=AGG?B9EB@75@48=99?8?BBAGH;;=52+.348<334(- +@SRR11410539.392938 392938/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCTTTGCCTAACAAATATGGACTGAGACTGACCTTACTAAAGGACCTCATGAACCCCGCTCTCCAACATATAATGCCTAGTTAAACAGGGTGATGATTATGTACATTCCTTACCCAGATCCATCAAGAATCCTAGGGGGCCGGCTGTTTTGTAGATGATATCGTAAAAACAGATGAAATTTTTACTTTATGATTGAACGGTTCGTGTCTTTAGCTATAGTGCTTACCCACTTCCCACTAAACATCCTAATCAGGAGTATGCTGATGTCTTTCATTGTGCCTGGCTACATAGAAAGCTACATGATGAGTTAACAGGACACATGTTAGACATGTATTCTGTTATGCTTACTAATGATAACACTTCAAGGTATTGGGAACCTGAGTTTATGAGGCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ ++./2>/&&AD@Q17,<0/)A>CBCH<=>::1DHFBE+==CA>;2<:>>;()1B>>A:0,.--.,$%&.''(-/*%%-6:>33478;-*6,8=7::>>BC-+D?7:9=3.-(&$$$$.16.3$5()'(%$&**.+%#(->7=DF?==>66@65:9BF?;2*(#%%%(/-&(-05766A88A=7=++25@**/1''('3;C@=DACB>>D738?8DA?>>A;AAB>882234743/'#$%-*,:9=<:67<'+==3-E;679>:111-810)0*,-.@B==953..$$&.6/;;<=><;:58790656-AC?=?268FLAGIB?BDB0@DG;JHE>?64CDAB>:BCDKE+=;A@E??B@:+88=87CDA886956438@AAGC9632%% +@SRR11410539.1236414 1236414/1 +CGTACTTCGTTCAGTTACATGTAGGTTAAACAGGCGACTACAAACGGAATCGACAGCACTAGAGTTTCTTAGAGACGGTTGGGAAATTGTTAAATTTATCTCAACCTGTGCTTGTGAAATTGTCGGTGGACAAAAATTGTCACCTGAAATTGAGAGTGTTCAGGCATTCTTTAAGCTTGTAAATAAATTTTGGCTTTGTGTTGCTGACTCTATCATTATTGGTGGAGCTAAACTTAAAGCCTTAATTTGGAAACATTTGTCACTCAAAGGTTGTACGAGAAAAGTGTGTTAAATCAGAGAAGAAACTAGCTACTCATGCCTCCAAAAGCCCCAAAGAAATTATCTTCTTAGAGGGAGAAACACTTCCCCACAGAAGTGTTAACAGAAGTTGTCTTGAAAACTGGTACGATTTACAACCATTAGAACAACCTACTAGTGAAGCTGTTGAAGCTGCAGGTGCTGTCATTCCGTTTGTAGTCGTCTGTTTAACAACAACT ++ +'$&'02568A470@:;55%#%(((?>:9;=3+-&.311-*$-/&,'*%1:9<;8:7894(:0*-4;;EGAD=;>?E@BB>78/(+,,2:26+,,8=@A?@.@33>=B3?523507:872@+19=@98@A275:@30+)(('-*/430#$$%&BA956%5677;68@=5:;BA>=D;;89B9,<=:@5<:**=BC=;99@7<;9@D?@++,,*(*127(-,+,5646/()$%'%'337:?<::;CC>>=?98??4474-520/,::>B56*1(#$(.-3890598//,,.-1:<=B74569::>?:;974/.*&&&$%($ +@SRR11410539.1479416 1479416/1 +CGGTATGCTTTATTCGGTTACGTATTGCTAAGGTTAAACAGACGACTTTCGACGGAATCGACAGCACCATAGAAGTTTACTGGCGATGGTTACTTCATTAACTATATGCTCACCTATAACAAAGTTAAACATGACACCCCGTGATAGCGAACTTGTATTGACTATGCCGTGCGCGTCATATTATTAATATACAGGTAGCAAAAGTCACAACATTAGCTTTGATATGGAACGTTAAGCGAAGATTTCATGTCATTGTCTGAACAACTACGAAAACAAATACGTAGTGCTGCTAAAAGAATAACTTACGCCACAGTTGTATGTGCAGCTACTAGACAAGTTGACAATGTTGTAACAACAAAGATAGCACTTAAGAATTGGTAAAATTATTTAATAATTGGTTGAAGCAGTTAATTAAAGTTACACTTGTGTTCCTTTTTTGTTGCTGCTATTTTCTATTTAATAACACCTGTTCATGTCATGTCTAAACAAGGTGCTTTTATCCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCATTACGTAAC ++ +.$*)$###$&('&%2)/:=;732/;?6?7))22>;8<;5272)($&)))'+12.3/9:==@/3+0..+*(-%&&&,/+&4<:>A?@B38&.+'''#'$&.-()(/9''*/9?>?80033835*8)-%+-1%;=78549;+)%#$$%%%+&$#$%&)))+*(),&$$&&'*%$*987?(%%--&-1.,'&'&%&'974@<56+**6834322,7+)'%&,:?B;79;=63'%%($%$%)*)--<@D?6;38;:@A;6:;6688/,()$%()??IF?DEIE:;BIK68D6/:9?--056%%%%,&(7451212+55.447;<A@A==%*9BAA<BNF@C9B@99C?ACC88LBA96BC?<<><<;A:9I8F@8D@G999:8:01=5:@?99:5:93/,-+'*01-,&&& +@SRR11410539.143872 143872/1 +GATACATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACACAAACAGAATCGACAGCACCTAGTTTCCACACAGACAGGCATTAATTTGCGTGTTTCTTCTGCATGTGCAAACATTCTCGCAATTCAAAAAACAGTTCAAGGAATTTCTTGCTTCTCATTAGAGATAATAGATGGTAGAATGTAAAAGGCACTTTTACACTTTTGGCACTGTCTTTGCCTCCTCTGAGGTGTAACCATTTAAACCCTGACCCGGGTAAGTGGTTATATAATTGTCTGTTGGCACTTTCTCAAGCTTTCGCTAGCATTTCAGTAGTGCCACCAGCCTTTTTAGTAGGTATAACCACAGTTAAAACACCCTCTTGAACAACATCACCCACTATATGGGCATCTTTCTTTAAGAAAGTGATGTCAATGTCATAACAAGAGTGGCAGAATCTGGATGGTGCTGTCGATTCCTTGTAGTCGTCTGTTTAACTAGCAAGCAATACGTAACT ++ +$)-&%.448:64/99828:?A<5BFFJ=<@??7KHCDGB<>;<77/-23<<:-0'0>>@AD;;;C@=<0),26A:<=32-&(,.,17B<=@@@;>J8.*BA??BB?@@DDF@??@>765%.+.0(('#&&($*0,,)+:69=9A9:00',478>A<@@22>;>?78,7DC6:588@>@B63?BF;AA>;4*(316;A=?78;A>ACA7()%*2:688<;AA==@AB?DC?7981376*++4=>88985+,-,03/>6>??139****,$%-%&$(()+400,9%;4AED>24-(0>>>>>DAA>79;;:9*+#%%'*,*,;>995)$8%(9:>@?89.0:;?A::>658+433()896/,&'$*6=>FFF?NLA618:D??GGGJA:>;<8=;@88:8:=>6-;J@FEHB=?;E>56>:/0C709B=@87@8')+-..46EHE4.'&&'(&''2/0<=HDE?;,. +@SRR11410539.148880 148880/1 +CATTGTACTTCCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAACGGAATCGGCAGCACCTCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGAGGTCTTATCAGAGCACGTCAACATCTTAAGATGGCACTTGTGGCTTAGTAGAGAGTTGAAAAGGCGTTTTGCCTCAACTTGAACAGCCTATGTGTTCATCAAACGTTCGGATGCTCGAACTGCCTCATGGTCATGTTATGGTTGAGCTGGTAGCAGAACTCGAAGGCATTCAGTACGGTCGTAGTGGTGAGACGCGGTGTCCTTGTCCCTCATGTGGGCGAAATACCAGTGGCTTACCGCAAGGTTCTTCTAATGGCAGAACGCGGTAATAAAGGAGCTGGTGGCCATAGTTACGGCGCCGATCTAAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGATCCCTTAAGGTGCTGTCATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATGCAACT ++ +&$('586333%(377)%29:3@9<<;=.99./''DHC>@?-)/(2-,*(%%25*8'+&29;%&-0)<8EA@@9>8655==>GFLCB<,-%&&666>;?64&-+8B<@B@7323,&28,;67@44565-4445&:B5696?2=/2%&'*0>=;D+2<<=FCKI<<7:;')++,0071-@C@AF@BDB??9>4>:;76$$8=3681..2.,)*13,===:@HHA?<99;@9A<0./145:-&2<;=@DCB@@%:44(BHA=?+1*##$&&%++1:%%;;?B?AC;H3-7,8>>;>8<<:9&-+4..);+49FFCA9.@2DG=:3@E=>>FHD?@@8=;@=B>:;7...77:()786''<))122/>?6:;63=00427:@=6@=>B::9?C:755;@=<>))&&&$$#& +@SRR11410539.492258 492258/1 +GCGCTTCGTTCAGTTACGTATTGCTAAAGTTAAACAGACGATACAAACGGAATCGACAGCACCTCCAGCAACTGTTTGTGGACTAAAGTCTACTAATTTGGTTAAAAACAAATGTGTCAATTTCAACTTCAATGGTTTAACGACACAGAGTGTTGCTTGCTGAGTCTAACAAGTTTCTGCCTTTCCAACAATTTGGCAGAGACATTGCTGACACTACTGATGCTGTCCGTGATCCACAGACACTTGAGATTCTTGACATTACACCATGTTCTTTTGGTGGTGTCAGTGTTATAACACACCGGGAACAAATACTTCTAACCGGGTTGCTGTTCTTTATCAGGGTTAACTGCACAGGAATCCTATTTATTCATGCAGATCAACTTACTCCTACTTGGCGTGTTTATTCTACAGGTTCTAATGTTTCAAACACGTGCAGGCTGTTTAATAGGGGCTGAAGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAA ++ +$&$'*.25<04*<280@;<8::%$.79;7)#'$#('%**+--,,//7>?9?444876382AA=9*+=>CFBD2.35663?@448F>A>AB9<@B+=EB7>BCD=::8281513E@875=B::805:CHF551&$0//,-'=@C<3&#&&+*,///(:-0035618??>3/227:9/2>==DA?B:(.0&&229??=@565621988@C;>64.-02//99?9779;4311076578>@AALD@>CC6C?>B=3B<<9;@95+$$*01(414%)20BCGHHBD=;-B(BCGG04FJMABNAGE<=<=<9,.*-)$*-+'/*+&&&.%('**134>=.6@08,((627-&3''$$%))512($&,2/38;25-1-40>4435:;98>;501/202CA35;0+/;6=D3.;33=0(+26;@55++5414489@A:()%)%,/..22/.633%+ +@SRR11410539.1935584 1935584/1 +CGTGTGCTTCAATTTCAGTTACGTACCAGGTTAAACAGACGACTACGACGGAATCGACAACTGCCTAAGGTGTCACGATTTCATAGCTCTTTTCAGAGACGTTCCGTGTACCAAGCAATTTCATGCTCATGTTCACGGCAGCAGTATACACCCCTCTAGTGTCAATAAAGGTCAGTTGTTCGGACAAAGTGCGTAGGCTTTACCAGCACGGCCTGGAAGGTCCTTTAATGCGCTCAAGGGTAGCCTCAGGGCTACAAGGAAGTTGTTATCGACATAGCAGGTGCTTATGCCCTCCGTTAAAAGCTCACGCATATGAGTTCGGTACCCACCACTGCTGTTTAGTCGTTCCAGTTTTCTTGAAAATCTTTGGGATCAATTACCAAGCTCGTCGCCTACCAGTCAAATGACTTTAGATCAGCGCCGTAACTATAGCCACCAGCTCCTTTATTACCGAGTGCTGTCGATTCCCGTTTGTAGTCGTCTGTTTAACCTTAGCAGCCCGTAAC ++ +#$*')$()('$%$*;/+7771+$%%%(')156;B@8582,&$%*$$&(+#'&)('%##$$#%#'(+'()-4/*&$*'('*0:))5.<<@D@@8**'#%&%$')$&&+1523@>A??>@?B(*0.2-$,$;28CF6>/+;?@:<0,(+$%&4562)((%$$$%#$%%'$&%*''%%)*..))*'%%22=;;(1966$$$%-&.(&#(%'$%(%',221%*(20))&0#%&%'#%&*&$%%$$%++))'(*.)&&%%%..5+'%%$#$)*).86&%$%$#''...*).''%%/1.'+('&%%',$')10.%#$))',0--((&&'<=5=)+)*&*3128?CC64=D554/%&(7/'>?>;4%&&&/84,-,00--0=?@@4=;A?>9@;AC>3?GDDFA?GFFJ@;=A9:<=;LA5.69;857;A@@42<55>EFDGJE<99<0)-989423&,)()&&''&#&(+./1-$%$('('$',*3165;<>BB88=?),)2'*/027((()'(78:?=?=A>96@;6>@=--40./.+%%)$042;;=AA-1,)',-21126$$./66B2?5;9=628<+:CE863<97(&58979.'%%-1B<@B47??I3D-;>:<98F@=>=/5130:8=23DJIECF?BE>:8@@B;FB;16A26678,./$$$%0%%=>?<;>?0=/';69FFB@EBCB>?B5=I79F?==:>;=855/3>4HLDCF59,-%%"#%%%'%'.+106<3<6-@352<@647-5445B0154:98%$$$$69<96<577>A2267739,4CB;:3D@0-#$ +@SRR11410539.1882773 1882773/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTTAGCGGCCCCTTCTGTAAAACACGCACAGAATTTTGAGCAGTTTCAAGAGTGCAGGAGAAAATTGATCGACACAACACGAGCAGCCTCTGATGCAAATGCATAAAGAGGACTCAGTATTGATTTCTGTTCACCAATATTCAGGCACCTTTTTTAGCTTTTTCCTTTGTAACTTTTATAAAATTTCACAGGATTCAACAATTTGTTGAATGCTTTATAATCAAACCTTTCACAGTTTCCACAAAAGCACTTGTGGAAGCGAAAAGATGCTGGAAAAAATGGCGATCTCTTCATTAAGTTTAAAGTCACCAACAATATTGATGTTGACTTTCTCTTTTGGAGTATTTCAAGAAGGGTTGTCATTAAAGACATTCGGAACCTTCTCCAACAACACCAGGTGCTCATCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +(+-396;=>>9>@@BC>?::820%%.2&,%57=DGDBB@2<>CCAD?A-54CDLC-.4*:AC0,E;0:B:C;4:D?81)',7;8;::8))1,(,,():+117068:@CBE@?>@(3(9ABA=B:?8=EFGE??C??EB+=B>?FB?54;HB33-/*-*&+856=?@=>33+3%%C;)04/)$&&',4966(423=;A?CC@H@3.-..+(;DGFHIA>C8BAA?>HMIJC>:)A)CDFE@IKJEF;EA@4*,(-828<:9)*.&&-/)*%'./+69>)/)8?AB/8:);..223C>A943/+$$.()6<>CCC;>>HDH8;FC:=98@?ABCKABCDHKKA=>@EC=CD5.$) +@SRR11410539.1425784 1425784/1 +CAGTGCCGCAAACTAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAAAACGGAATCGACAGCACCTAGCCTCGCAAAACCAGGTTCCCAATACCTTGAAGTGTTATCATTAGTAAGCATAACAGAATACATGTCTAACATGTGTCTGTTAACTCATCATGTAGCTTTCTTATGTATTGTAAGTACAAATGAAGACATCCAGCATACTCTGATTAGGATGTTTAGTAAGTGGGTAAGCATCTATAGCTAAAGACACGAACAATTCAATCATAAGTGTACCATCTGTTTTTACGATATCATCTACAAACAGCCGGCCCCTAAGTTCTTGATGGATCTGGAGTAAGGTACACATAATCATCCTGTTTAACTAGCATTGTATGTTGAGAGCAAAATTCATGAGGTCCTTTAGTAAGGTCAGTCTCAGTCCAAAACATTTTGCTAGGTGCTGTCGATTCCGTTTGTAGTCTCGTCTGTTTAACCTTAGCAATACGTAGC ++ +"#$,'$%#&#$##&#**../9<><9--4%%/;LEDH@DBAD=B@?@F?;=<@9:.1-877:??@DBEHEEE>B@BC((9:=/)/&*=F@:;@@CD<:419;;;>@BB?<:>=D=01BBC?=AB?=?227::;>1++4479?>2-:38=?;>=?A>:;421+2%((-E>M=,<<>:8:B@9:31,679<733349:<**73%%:=??*;(@?@:;5BDFDFF?6B9)'/??AIB99@4C@:B:==@B/'/2,(&&%)$%"*09;7A1:7;:DGEBA@CAE?@@@KCD2:))9><>?>A8>824=;/:?=>@J:<;3'(,'-85>?>;58:2(626'57&'/+2,389@=C@507447:7:8:/03;5:CE?=:878DC<@?@A;3109;89>@A91@8*+'6365;;?@A;A229120(5>=@IC575321C??:>8::>B<134=67ACBA:8788980'$&%% +@SRR11410539.1133190 1133190/1 +CGATGTACTTCGTTCAGTTACACGTATTGCTAGGTGCAAACAGACGACTACAAACGGAATCGACAGCACCTCCTACCTCCCTTTGTTGTGTTGTAGTAAGCTAACGCGCATTGTCATCAGTGCAAGCAGTTTGTGTAGTACCGGCAGCACAAGACATCTGTCGTAGTGCAACAGGATATTCACTCATTATTCTGTAATTTGACAGCAGAATTGGCCCTTAAAGCTGTTACAATAAGAGGCCATGCTAAATTAGGTGAATTGTCCATACTAATTTCACTAAGTTGAACAATTTTACTATCTGCATCTACAACCTGTTGGATTTCCCACAATGCTGATGCATAAGTAAATGTTGTACCATCACACGTATTTTTATATGTGTTATAGTCTGGTATGACAACCATTAGTTTGGCTGCTGTTGTAAGAGGTATTATGTTCAAGGGAACACAACCATCTCTTGCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACAATACGTA ++ +%%%&).-45=.AN;@8@?=-(+=?B@@<-/(%($)&04778C?&%(+=@BC@=CG63CDB@<;2/>634*(.3....1,&)-179;7845131+.+->B:5-+02.*855.-6:113:E>1=C>FGEAEF;<;C;>A;5C@BAC>9;DD69OB?=@-<=@=BA=BCGC;;C@IA@?676837565;:7:65;D<=?>?793529;?B<=CD=63=>GCF=4DCCIHIHKJD@EF?B:ECFIHD?8A9<==5A6459<@C=CEDJIC?))0235BHFFD?DC<=01/>?;@BK>99CA@>D8=IJC>BA-8DEC>B=CCJF:9:?MKOACE?8;89>7;;942+(--,,1,)) +@SRR11410539.59797 59797/1 +CATTAGCCTTCGTTAAGTTACGTATTGTAAGGTTAAACGAACTGACTACAAACGGAATCGACAGCACCTGGCACATGGCTTTTGAGTTGACATCTATGAAGTATTTTTGTATAGGACCTGAGCGCACCTGTTGTCTATGTGATAGACGTGCCACATGCTTTTCACTGCTTCAGACACTTATGCTGTTGGCATCATTCTATTGGATTTGATTACGTCTATAATCCGTTTATGATTGATGTTCAACAATGGGGTTTACAGGTAACCTACAAAGCAACCATGATCTGTATTGTCAAGTCCATGGTAATGCACATGTATGGTGTGATCGTCTGTGACTAGGTGTCTAGCTGTCCACGAGTGCTTTGTTAAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTGTGAAGGTTCAACAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAATACATAAC ++ ++%$&'&&&'*$'5)%%*121500.**&3/0-ALEDH/7++3++<762:6774/$&$09<@E>8B@B<@BEBI@C==50//-<=4-*3<:>@>50.-(,-,-,,5-+$&5;;;=A==<@=>?:?@ECEF@:<@@9:<;8348,/,;@<>0330//12725.():7886-,34/,-16:;>?<==7;?;7A9:=91+-1*0*9<@BAA?28;:;5('148;A:HH:CFGEDGHDCE@@934=446-0<;CB7$$&'))78DBF<=GHC:?>><;4320*@2=C?DE2,ACD?68;;2?CC6;@?BDD7((%%000<9960(&'02$$9==>6521=624.)4>=@23@JLGDJH+-D=AGHEB>>::;>A?@98=>??=B78:F=:+++-9=?>=<67ADD?:43<&-(6;--3095>46;<;;CCEB=?:>=E5AEB;>9491&-,+01%*%$,--/0(**+' +@SRR11410539.1172049 1172049/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTCAATAGCCGCCACTAGAGGAGCTGTAGTAATTGGAACAAGCAAATTCTATGGTGGTTGGCACAACATGTTAAAAACTGTTTATAGTGATGTAGAAAACCCTCACCTTATGGGTTGGGATTATCTAAATGTGATAGAGCCATGCCTAACATGCTTAGAATTATGGCCTCACTTGTTCTTGCTCGCAAACATACAGCGTGTTGTAGCTTGTCACACCGTTTCTATAGATTAGCTAATGAGTGTGCTCAAGTATTAGTGAAATGGTCATGTGTGGCGGTTCACTATATGTTAAACCAGGTGGAACCTCATCAGGAGATGCCACAACTGCTTATGCTAATAGTGTTTTAACATTTGTCAGAAAGCTGTCACGGCCAATGTTAATGCACTAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTTAACACTTAACGTACGTAA ++ +*--)+*9:;76H15-4A@>:8:=CF?A?$&5BMGDH=6061187:;9;<=:5,0-7;54317:=D>?J>;/-*,-;<=@?A>;A7?:C22.,-/32>>=>@=?BB@CC<@@@@CAB62147D;A==40+.3/+*>88EDABBA<;?DDE;3/.0:789'68230=)@B?@?:44+09F?-3@=FB-);.>FC;<88:=998IFFB;=AE?@>=G@==@B8:>9CC<AJKF<>;=(=%65@1;;-+57>??:6?:2=:>;?<7%?C693BEA9A@E@C=9;BD?MEF=A>?>:8+@87629>FFAA66::C;>IIGK>B;25??DD<;8;:>7:=<989;:9576.6117;77>AI<;??;>5>>EB=>E76=EBA?HB:29+,,'?@<@@C@E>><<06BEBCFFB@13>>B>7:;;52;964=>$&3=8:302+20569:9;;4,+/'#$$$$'#&#$$$#$ +@SRR11410539.2265078 2265078/1 +GTTGTGCTTCGTTCCGGTTACGTACTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTCCCATCTGGTAAAGTTGAGGGTTGTATGGTACAAGTAACTTGTGGCTAACTACACTTAACGGTCTTTGGTGCCGATGACGCTGAGTTTACAATCTATTGGTGTACTTGATCCCTCTGAAGACATGCTTAACCTAATTATGAAGATTTATATTCGTAGAGTCTAATCGCATTTCTTGGTACAGGCTGGTAATGTTCAACTCAGGGTTATTGGACATTCTATGCAAAATTGTGTACTTAAGCTTAAGGTGATACAGCCAATCCTAAGACACCTAAGTATAAGTTTGTTCGCATTCAACCAGGACAGACTTTTCAGTGTTAGCTTGTTACAATGGTTCACCATCTGGTGTTTACCAATGTGCTATGAGGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACATGGCGC ++ +-().:3:===9A?$)%*770/*)%00,-*(0'*%:</=:?;=??2$%#$$$')+,)5%$('$',3,$)''%($""$$%&#&$%&'*)))+():899=;,''&%#$&%&;@GCKA5401,,+59;/4;=?58E<>'(<83,;=<4;35702&&+;ACEI>>:669;3A?A7897--//68<5?B0399;<:?@59>?::3,68BC;>-=?BA?88.3.39;:==69:ADL278:ABJ98866726HFG84DE?HAA@?@*;417833>3>3<=;6-2+,&%%%%'%(8>;B@B>CGM?IC?@&5>@4,DI=.6=D>@?+@;69@>A?BF@HDFE5C>-;;22>@A@49FH<98=DD@@<:3,=;:>?=A@>?1;,++-.+.9=01079>CECE?@AIE@DB?DIBLIABKCFENE@7748?A:959;AFD9?973&&5.05;@;=;9@CC<@A<=H?<3@B=?432')<(=>>7=25AFEDD@==GD3/2:B=C@AD=A?AE::/DJEAA3''%#$688<24,.:9-7:?98>>:7:EAA?7*)-.?=>A75@7879>::5.>CAIDA?>7:?DE?AA?BCA@RKRGDD@BFLHFAB>?C=A8=AE;=:>BFG=6:(),%%1=*7*>?1EEE,&,556*B<75*1'+?=<=1//,7(55336>138?<%$$$&.4;01=:B@A6299&((',,**3(9<75><8,$1123@C=749A9?958:;9:37,%,&&0*)7:)))D8AD<97-)):1=BD66EDDDBGH>E<B72.112160(..?>>@<>CEI77B338B?<:FI:4;=''=<:>=:0+('(.*+++(+//:73?=<34;>4**&)&&78)$?%-;:0<=A3CDABB&;;:<27ED>>CDBFEKE1@@FDC<=C<(79;844)*%'6;?AFC=9+)% +@SRR11410539.638293 638293/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTCCCATCTGGTAAAGGATTGAGGGTTGTATGGTACAAGTAACTTGTGGTACAACTACACTTAACGGTCTTTGGCTTGATGACGTGATTTGTCCAAGACATGTGATCTGCACCTCTGAAGACATGCTTAACCCTAATTATGAAGATTTACTCATTCGTAGTCAATCATAATTTCTTGGTACAAACTGGTAATGTTCAACTCAGGGTTATTGGACATTCTATGCAAAATTGTGTATAGCTTGAGTTGACACAGTAATCCTAAGACACCTAAGTATAAGTTTGTTCGCATTCAACCAGGACAGACTTTTCAGTGTTAGCTTGTTACAATGGTTCACCATCTGTGGTTTGTTTACCAATGTGCTATAGGCCCAATTTCACTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATAT ++ +-))1631237:C?2-57;,B;@B4@30../7AI@;=81*/+9822269:=8=8:BF?>A=1+;<8;;A?@A=9:B7@C>=15@:C66./8;7:;<@@B9;<>BB<12$$%)%%%$*%$%#'('(%%7446;/3320862/'#%',,,+)).4.1221.023=>29=>;647.*(&&%$%&$$$,-01;;,--%''%%%'#2317>@@@DE;@34>81/62,>B::=021/$$%231348;:*)).&()'(+.+***'&,/0('$%%$%%24$$):<=>830('+*+')%$015:?D?;02.:898B<>:6?4A?8--:AIIP90*;?;3.+&),.5?A;A<443$%.**/(*9@9./+8$4884+&'&&$9446&'&*'+(>*JJE?>=46477:9;;=F>>CCFIAB8(*@GCGDAD=:589:9:20279C@@??J@@CA::;?05@609757.,8:@@A:>CB@(@ECED>BEF9B@A?<36#%$('%($#$$*-069@FJ:FB;690=??>=?>>D@@9:;*8;?:8-.74@968=76<=<@&'(::ID:;@+47@:1A5**7@:DCC:75,+)//39@>:(157:?>=>?><=9,*%%%$%%--7))%# +@SRR11410539.240762 240762/1 +CGCGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGGTGAATACAGTCATGTAGTTGCCTTTAATACTTTACTATTCATATGTCATTCTTTGTACTCTGTTTAACACCAGTTTACTCATTCTTACCTGGTGTTTATTCTGTTATTACTTGTACTTGACATTTTATCTTACTAATGATGTTTCTTTTTTCGCACATATTCAGTGGATGGTTATGTTCACACCTTTAGTACCTTTCTGGATAACAATTGCTTCTATCATTTGTATTTCCACACAAAGCATTTCTATTGGTTCTTTAGTAATTACCTAAAGAGACGTGTAGTCTTTAATGGTGTTTCCTTTAGTACTTTTAGGAAGAAGCTGCGCTGTGCACCTTTTTGTTAAATAAAGAAATGTATCTAAAGTTGCGTAGTGATGTGCTAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTAACCTTAATAACTCTAAC ++ +##$&&%7:<<;O23*=24?A=KHFIDE>91*:BB?BC=33>9?6/==:::7?02:E>>@A8@4?4976913>9:EEEB?<2:BC=?B>DFE>BBEA@A@@56EC;>CB@=9=6?02@ADDDBAA:++32)().*+,5::--/ECB@A?PFB=?G>5@8<@A@@A=<=F>@C=:<;D<=>=:;=@>:::;@BB@B@D@@>13/31../%'+..*7DJ4@???K36,(@?KJ:@?DIEA=;9@A8;CD9HD@C>BJJFIEA0=INE089>96C:,#*68BC<@@@77=>9GGHCKF?B=>;;2*(0ECFB=6A===85KM?3<=AB@//&&3/08BDCDE2+<<>9@:;:9576)$%'45;;=0=>?F@ABC:?C=984(96:54=,+,))+-+89BKC7A27?A;HF;>CI@B@A@=<58?B;<8:AB@?=:@@EGEIHF=?@?>4&+8750+4?4/>88$$'1*11;BEDD;I9?9=-...+.2,,,+%%%+%$%'(0(6'.-*4-*,$#"#*69=A==+&786/02913*7FGEA?3G/22?AC>66CD@@CDC6::/,*5:43867;8..&5''.::&=>1;.08<;*7,16/%&**(-3;@;;=?;536<>=>@@5&4%+9<6CFHBEMHE<ACFB@955,7)44+.0-*)$"&:@1477=B=BGA@7>=EFB=@>><7*4;@AEH:=C<*L?:<:DA?3)&$-0%-7&.&''0,2%8(8.-(*&&*(-($'$%*,'&%864'( +@SRR11410539.2352751 2352751/1 +CGTACTTCGTTCAGTTACGTATTGCTAAGGTTATCGACGACTACAAACGGAATCGACACCTACTTTTGAAGAAGCTGCGCGTACCTTTTTGTTAAATAAAGAAATAATATCTAAGTTGCGTAGTGATGTGCTATTACCTCTTACGCAATATAATAGATACCCAGCTCTTTATAATAAGTACAAGTATTTTAATTGGAGCAATGGATACAATAGCTACAGAGAAGCTGCTTGTTTGATAAACTCACCAAAGAAGCTCTCAATGACTTCGGTAACTCGGGTTCTGATGTTCTTTACCAACCACCACAAACCTCTATCACCTCAGCTGTTTGCAGGAGTGGTTTAAGAAAAATAGCATTCCCATCTGGTAAAGTTGAGGGTTGTATGGTACAAGTAACTATTGAACAATACACTTAACGGTCTTTGGCTTGATGACGTAGTTTACTGTCCAAGGTGCTGTCGATTCGTTTGTAGTCGTCTGTTGCTATAGC ++ +&(&&49=>>FB?7:=?/;>CC?=:=7<@@>@>?:BA%$$$<:@D5/EKCF<==<<9>78865@@<=>;*+))&(*'8<>=-./366106;05=C9>74+>90))('-29>83:994:.(()&&+..%+'$074<(0--*57333-$''()686',@?35,,-@>=;432'+./++&&+,,3768-::;>?0*7**+0,2$%::21A656+*-56;?=>@:87521,,1()2=8+%1&&(.+,30,&-74%%(;?<>?9:98601/23??A???>4-;464-,75..9./(1>==E82/.')'+-02A@B?@;=;;;52()#$'&$$$# +@SRR11410539.1152939 1152939/1 +CAGTATGCTTCGTTCAGTTACACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGCCACAGTACGTCTACAAGCTGGTAATGCAACAGAAATTACCTGCCAATTCAACTGTATTATCTTTCTGTGCTTTGCTGTAAGATGCTGCTAAAAACACAAAGATTATCTAGCTAGTGGGGGACAACCAATCACTAATTGTGTTAAGATGTTGTGTACACACACACACTGGTACTGGTCAGGCAATAACAGTTACACCGGAAGCCAATATGGATCAAGAATCCTTTGGTGGTGCATCGTATTGTCTGTACTGCCGTTGCCACATAGATCATCCAAATCCTAAAGGGATTTTGTGACTTAAAAGGTAAGTATGTACAAATACAACTTGTGCTGACAATGACCCTGTGGGTTTTACATAAAACACAGTCTGTACCGTCTGCGGTATGTGGAAAGGTTAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTAACCTTGTAATGCGTAACT ++ +&$&)*,,;=.00?;;1:DB7$6=F=;AAC:>A;@@CD>>HCA@%%721/1$%&93(=+**0=464..&'1,1-.50//,.21&%55>?()=9BA?C@CDG=F@?CFC64:::564<<**-)-$%.(97CA''?%%%78:845+)131BDEA.<>?:BBEI>+)4E@C?>@2167@AB82$/./9:;;=11200.$$%+'@A<>2><8=EGG/%1$'%'-/824430;7<6=773;?49B.:HA>::;@8<.?C705&<>@@A;8;?AJF<>8@?275:9>78=9,:;+983400*+**'&)*,-/-) +@SRR11410539.366867 366867/1 +CAGTGTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAACAAGATCGACAGCACCTCAGCCCCTATTAAACAGCCTGCGTGTTTGAAAAACATTAGAACCTGTAGAATAAACACGCCAAGTAGGGAGTAAGTTGATCTGCATGAATAGCAACAGGACTTCTGTGCAGTTAACACCCTGATAAAGAACAGCAACCTGGTTAAGAAGTATTTGTTCCTGGTGTTATAACACTGACACCACCAAAAGAACATGGTGTAATGTCAAGAATCTCAAGTGTCTGTGGATCACGGACAGCATCATTAGTGTCAGCAATGTCTCTGCCAAATTGTTGGAAAGGCAGAAACTTTTGTTAGACTCGAAATAAGAACACCTGTGCCTGTTAAACCATTGAAGTTAGAAATTGACACATTTGTTTTTAACCAAATTAGTAGACTTTTAGGTCCACAAACAGTTGCTGGAGGTGCTGTCGATTCCGTTTA ++ +*$#&(-(--/)(-)-&0<>B@<<><(1I8>0/0:4:B744963=/ECLNJAGEJLI50-9=<++*+,-247;;8;<6AE>?@DK>J;=()')(4704.'7:@2,)4541389>,)6=@;939:CED?-);DF@D6:89:;<@5/79;4=?:=;?46;D70/&&*3646:29-0=/5-6-2*$#$%16657=04;<:99;?;....02337'&*%)14(045)(+4,@*B;@AC32;B@@?B?-*,$$5)# +@SRR11410539.1660182 1660182/1 +GTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCATGGCTGCATCACGGTCAAATTCAGATTTAGCCACATTCAAAGACTTCTTCAACTTTTTTTAGAACAACTTCAGAATCACCATTAGCAACAGCCTGCTCATAGCTTCTTGAGCAGTAGCAAAGCTGCATATGATGGAAGGGAACTAAACTCTGAGGCTATAGCTTGTAAGGTTGCCCTGTTGTCCAGCATTTCTTCACAAAGCTTGTTTATGTCTACAGCACCCTGCATGGAAAGCAAAACAGAAAGTAGTGAAACCATTTTTCAAGGCTTCAGTAGTATCTTTAGCTAAAGAATGTCATTGTGTAACTGGACACATTGAGCCACAATTTAGATGATGATTCTACTCTGAGTTGTTGCAAAACTGAGAGTAAGACTACTGATGTGCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +$&%-&,,18;C,:5:DE?A=GHFG?ABC9.A?9:;18--=->??20-/0')0337::@EDJEC@::CAFEAB?=0;618HKCA9>45448@=<=CB;;333CDDEC=;<0/($4:;;2.*+>??@JC@.@&=56,,+6+8D5ED=ADA@BHIFCDGHBGAC?FCD5+%$$$"%.115;:56),5<3666.'021378489=98:*4;=BCC:=;>=??>D>@EB>>=?;9,@A>;//9:==;EGMJE<:756CBFEB?KGCIAGE:;@FG:?=>A?>:=,'77:<>EC?AAC;;+/7511:@BHE=;8?6238,.,9(39;<;@BIC1856)0''9>;8@A6-889DFGFB?:CD*&+;36=A?@@=B9>;5=BADCB:0-+/=7?9.$%*3*-;<>?C//B;A>;CC88>C27+:EG@BC8AGGH:7797+5(CACC=5@DGEGBF6C9;C>>@=C::>?@=AD@;67AACFCDA31) +@SRR11410539.1874045 1874045/1 +CAGTAATGCTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTAAACGGAATCGACAGCACCTTTTGACTCCTTTGAGCACTGGCTCAGAGTCGTCTTCATCAAATTTGCAGCAGGATCCACAAGAACAACAGCCCTTGAGACAACTACAGCAACTGGTCATACAGCAAAGCATAATTGTCACCATTACTATGGCAATCAAGCCAGCTATAAAACCTAGCCAAATGTACCATGGCCATTTTATATACTGCTCATACTTTCCAAGTTCTTGGAGTCAGATGAGAGATTCATTTAAATTCTTGGCAACCTCATTGAGGCGGTCAATTTCTTTTTGAATGTTTACAACTGAAGCATTAATGCCAGAGATGTCACCTAAATCAACATCTGGTGATGTATGATTCTTAAAATATTATCTAACTCCTCCTTGAATGAGTCTAATTCAGGTTGCAAAGGAAGGTGCTGTCGTTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +&%#&$$$#'(.(;G=81>FD;==EFDDBA;GG)-DCCFJ8;254852-)*+)*-0/3645266:B>3BDAFADDAC8;;;:87DHCEIBEBGAD<;;;>@<=HBBC>C:=><<9*0++(+58?)):9:@C5GE>*+31267++-/.6:7679830,CB14?D9=:=0.-,*++;>8;>HB<=;@@>EEEA<=>;=>;72<89-A<87B?C;>A?5<<712/4;:9002,;<9?7;@<9976665.-,),3=A6=;?9;=A/5,-:7:BF)%&*$'',,9>=A.99BCEA?@?A>>:;@<=;*1578579E1182180/;:0==@9:C@@?AD>=?CFC<;:=G=A23=49?569?D?>A==ADDKFC>?DC@.&&-/54=7>?AH,408;;=<&74-,%);-.2+'&$'.:=;B>A?BGB=??;A;?CCI442625@.:@@=>:7.'()) +@SRR11410539.2289681 2289681/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTGGCACATGCTACGCAACTTTAGATACATTTCTTTATTTAACAAAAGGTGCACAGCGCAGCTTCTTCAAAAGTACTAAAGAAACACCATTAAAGACTACACGTCTCTTTGAGTAGTACTAAAGAACCAATAGAAATGCTTTGTGGGAAATACAAATGATATAAGCAATTGTTATCCAGAAAGGTACTAAAGGAATGTGAGAACATAACCATCCACTGAATATGTGCTAAAAAGAAACATCATTAGTAAAATAAATGTATCAAGTACAAGTAAATAACAGAATAAACACCAGGTAAGAATGAGTAAACTGGTGTTAAACAGAATACAGTGAATGACATAAGGAATAGTATTAAAGTATTAAAGGCAACTACATGACTGTATTCACCAAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTAACCTTAGCAATACGTAACT ++ +%566;7568APKGIA;3458;9:>65+.(($)-777=?55277=>;%.04<3((+6?<-/$%89;EC@CDEA677(((4ABHGGCB>BB*&+9D>>66695)::;4483?28GH614;'&,((&($-1/<6;=EE23.9A88@.?;;:;DA@A,(#1)0%(%0656;*A6<;AA::8-2D33599A1>7.%9E>?GAFHI@@?B=902':9<7@<=AC4+;$$$%///%+-'33=?A>B:;BE@@DEICF;?E?@9EOH.$'98&9:G=@AC@;<::@D?44:?B900@=FID?@BE:-/3-))*&-3352BGGICB@?;<>?>@EF4*/:=+,>AGC8?;:;EAEDA;385=88%-.<6:<40?<9?A;=AEAB051/%64878>8512978;:BDFD>?BED<.%- +@SRR11410539.2225052 2225052/1 +AACATTCGTTCAGTTACGTATAGGGTTAGCGCGACGACTAAACCAATCGGCAACTTTTCTCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTGGAGAACTCCGTGGAGGAGGTCTTATCAGAGCACGTCAACATCTTAAAGATAACTTTTATTGGCTTAGTAGAGGATTGAAAGGTTTTGCCTCTTGAGGCAACCCCTAGTGTGTTCATCAAACGTTCGGATGCTCGAACTGCACCTCATGGTCATGTTATGGTTGAGAGCTGGTAGCAGAACTCAGAAGGCATTAGTACAGTCGTAGTGGTGAACACTTGGTGTCCTTGTCCTCATGTGGGCGAAATACCAGTGGCTTACCGCAGGTTCTTCTTCTGGCAGAACGGTAATAAAGGAGCTGGTGGCCATAATTGCGGCGCCGATCTAAGTCATTTGACTTAGGCGACAGGCAACGATCACTTGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTTAGCCTTAACCGTACATGCTT ++ +##%$%+-6661-:5890-&$%,%''&+%%#$$'$'*$(+'(%%&$.07'&'''#$$$$+,.15-00/+.03?A7@3>=@:2=01;>8A;5,2,)(($%('(+,,(*'2+,.+)%)+++,/34-,%%'.'2/79'(,,+-$$*+%(.-$%####%)),,0''15-)*%%%(%%'%%'$%&*+++$##$$"#$$&&5'(+**)('#%&)*&-3+%(*''79<83&)9502667-29::@<>;=A6<4:<@<<:-/9886.041%1499-0-(1+(,&9?58&''&'',)(%&&(%&$&))**+/002<>55;8889==995;=5<3789;88;7.36EE303=<%%=;DD3041@GA=@=853-$'))9,?CB679398;;+'$$))+,.0%%0.$#$&$..4*0:/.,)+-8-02.61)),7=1(33==<@?:0$%')%%.'&&7#"%&%*.)3=,:@BAA@2BBJCH75==CHABLG:@GFA@AEHF5@=4BFCEA9:@>25888;AC@BFH=B@>BBCBBHIOJI=>BD?;899''/7++7:/.:ED@B@229>EE.+2,3/5<>BCCFD;=@JI,49B,3'&$&1(1;=<;:?ACH;6=@:786&&%)>BFE>EI7===ED66;'547('9H@7*-5EC?AFGE/E'G576,,949<;=;<@>DA2C>>:AC=/*7$%$<><335/$$$$8JH>?GH7E<8:;?A<<FFBD=?CA-+--3)('-14-514>?F@GIDEFGDCC;>==ADB>C=>?556;.45::,=J9(/@:326=A>DB>)./2($024;CEKFMP%2317/5FDCEA<@DDKGAB6ECJDA@@9@87A=:??B88=?846*3,-*(%%#$ +@SRR11410539.714447 714447/1 +CATTGCTGTTCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTAAGGTGTCTGCAATTCATAGCTCTTTTCAAAACGTTCCGTGTGCCAAGCAATTTCATGCTCATGTTCGGCAGCAGTATACACCCCTCTTAGTGTCAATAAAGTCCAGTTGTTCGGACAAAGTGCATGAAGCTTTACCAGCACGTGCTAGAAGGTCTTTAATGCACTCAGAGGGTAGCCATCAGGGCCACAGAAGTTGTTATCGACATAGCGAGTGTATGCCCCTCCGTTAAGCTCGCATGAGTTCCGGGTAACACCACTGCTATGTTTAGTGTTCAGTTTTTCTTGAAAATCTTCATAAGGATCTGGTGCCAAGCTCCGTCGCCTAAGTCAAATGAGCGCCGTAACTATCGGCCTGGCTCCTTTATTACCGAGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAG ++ ++$$%%&('3/3&()+&//20?>36;45,@HIIK:1,/-,0/.56767+*'%42/110()./1%9;<38B70,35?::7.0'%1(:??GFH>@$%::61@A=@;E;=%26;?9A<96;D?4,)$27A536')%'-*+.'972,+*,;9;614-'#&.+++5;>6712./?7=>;;52.02&((')2@BC:-474=??80'),0+,8/3C;<=;06:8:@.8=*7&9=36>8CBAC?82;>9:..*9''':-2<>@;8C>C9?9;70)**A8223455==@;>9@<89@>:;4%'))-95(;*(-9:==571-4$+&.)47982358@;;6,+'%*,&,569.&+,--(-./)$)68(1(+<935-=7;.$%$999;>>9@::541189+1@<94504#)%&%'$&$$%%%$$&((+()(35-/+$*'-337*,-6*+0+366300%&$#%&(*00:?>=>8C:1/'$28:79:=AA???=>9<=2/0069:;=?A><>467(,6>;>@2+,:>>?>788<>9?G8;@?812+(&&+,,306/0;DD:;;>A<88''/02@@5:9?C20+'*))#%#&%+2-1/*5:4./-79AC@D9.3)1.592>:?ADDB=<@30.150142.,585)4<@B>67625GBC?@>EA>==+CB81<9??999$(,+4:D@A?@?<:-.869@?B<=<848:@?B>@<;()'8?=<;*%,013?665:52*')48>>;A;>867%(.++*,**4+*)/'&&%# +@SRR11410539.699316 699316/1 +GTTGTAGCGTTCAGTTGCAATATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCATCTTTAAGATATTGACATTACCTCTGTCAGACCCTATCCACGGAGTCTCAAAGCCACGTACAACGTCGAACACATAAACGAGCAAACTGGGTTCGGACATGTGTTTTGCTCTCGTTGAAGCGGACAGGCTCTCATCCTTCTTTCAGGTCACCCGGACAAAACCCTAGATATGCTGATGATCGGCTGCAACACGGACGAAACCGTAAGCAGCCTGCAGAAGATAGACGAGTTACTCGTGTCCTATCATCAACGACAGTAATTAGTTATTAATTATACTGCGTGAGTGCACTAACATGCAGCCAGTGACAACCACAGTTTTAAGAAGATCGTTTAGAGAACAGATCTACAAGAGATCGAAAGTTGGTTGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATGCGTAAC ++ +$&)$(+*4987)'..3$2#%%(%&$$%$&4;@FF?==>=B=501,7474=03(/'10016989>=E@=93571//7/**;+,+/$$%%+).++#&$%+%+*)'$(&1+.&**:9;:>456((),,&'&4%),+)'%%%*$&%$#&*(%$&3$)(**#$$#&$#(43$&$%%(*###"%)(+687754&1$*)*%&')*)%+(.+(%%&&*.-&*58>3>IG>DACHG>@@B=:%%7,(*%%(&&-))7=6<@B@A?@>EG=A=@56@A<<9:>?7,'>CCFD,$%$%%&''))*)'$*''*01;91/$)-..;*%%$$,:9CA6E>@@:9.$)#1&&+.()(')65/0$%&&%'%($)(&$)%''*&--/7=700/---.**'*7&%*$&%7;2&:,-:7DDD67:=@>4<=ADDCC=6667515%&'($$857()$ +@SRR11410539.1242026 1242026/1 +CGGTATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCGCCTTGCACATCGGTAGTCTTACTCTCAGTTTTGCAACAACTCAGAGTAGAATCATCATCTAAATTGTGGGCTCAATCATGTCCAGTTACACAATGACATTCTCTTAGCTAAAGATACTACTGAAGCCTTTGAAAAAATGGTTTCACTACTTTCTGTTTGCTTTCCATGCAGGTGCTGTAGACATAAACAAGCTTTGTGAAAGGAAATGCTGGACAACAGAACCTTACAAGCTATCGCCTCAGAGTTTAGTTCCCTTCCATCATATACAGCTTTACTGCCTATCAAAGAAGCTTATGAGCAGGCTGTTGCTAATGGTGATTCTGAAGTTGTTCTTAAAAAGTTGAAGAAGTCTTTGAATGTGGCTAAATCTGAATTTGACCGTGATGCAGCCATGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTAACATAACTTAAT ++ ++%%)&(&%&));@=?(.@?<:;@93-59(71=24ME580/3..?>2C*,;7>3859C:6D>8:8-0>;9/825>A29()&$$%%*,29<>925565568;=>A=<3422/131//'':539:342**428?F@B@AA6'&&'+%0,*)--33@ADIG>A@BB;9;=2268'78;C<<>;2'&&..-&$19:CB;::''()(.>854487,)$%,-1/=4*-BD;:?>=692278:>:<2%+%%)%.&(('%&%$%$(%+,)*'$'''%%%;<::E@;=3,A,?<&<CDOC<9;5:**?:AB;>?JMC)&,14@<<,1-99:FFED>FBC;55?9NR@>?=@53ACEB><;889,('/55@@A6>.38?<;C><=:;;A57>GEJBAFB<>=;?AD<:-*.$'#$$&',-' +@SRR11410539.2288664 2288664/1 +TAGTAGCGTTCAGTTACGTATTGCTAAGGTTAAGTAGACGACTACAAGAATCGACAGCACCAGATGACATGGTTTGTAAGCCAATCATCTGCGCGTATGCCTTCAACAGGTGAACGTGTACGCCAAGCTTTCTGTTAAAAACAGTACAATTCTGTGATGCCATGCGAAATGCTGGTATTGTTGGTGTACTGACATTAGATAATCAAGATCTCAATGGTAACTGGTATGATTTCGGTGATTTCATGATACGCTTCAAGAAAGATGTTGGGTTACTGGGCGGAGATTCAACATTATTCGTGTTAATGCCTATATTAACGCCTTGACCAGGGCTTTAGCGCAGAGTCACATGTTGACACTGACTTAACAAAGCCTTACATTGGTGGGGATTTGTTTATTATGACTTCACGGAAGAGGTTAAAACTCTTTGACAGTTGCATTGGGTGCTATTCGGGTGTGGTTTGGCGTGTGTAGTCTGTTTACGTCTGCCAACGCTCCCTTCTATTT ++ +#$&&$*+2?5C;?AB9;510//352''-BB<33,+.0/<>B5531**#%168@?.5(,+*%%()%&#&%(#&&&%'+(($('#%$$$%&%$$&&%$##$#$#%$$#$,339:;=;6>=9><458?DC;@46=?;@C<;?D39>AB?A?@>?=>;;EEF=CBA@AD8<(&%%#$'$"$%%$%%(&&'$%$#&$&'%&$$'%('.$'$$%)-&$%&%*379<+$72129<@B@AB?;>6+,%3452<7<=DAA=A<@CMH=M=5-&,.*%&)%%&2$#$$''%')+%/0+%)*'%#$0:?=6C;C88JKCD,*7BA><<<9%'37721)($&'*&*,/0%'$/'%'$#&$$'%,$+(-'+.&(&$#%%$%$$%&$%,.-%&((-,++,''(%')).++2,+*14, +@SRR11410539.2011633 2011633/1 +GTGTGCTTCGTTCGGTTACGTATTGCTAAGGTTAAACGAACGACTACAAGCGGAATCGACAGCACCTTGGTGAATACAGTCATGTAGTTGCCTTTAATACTACTATTCGCCCATGTCATTCACTGTACTCTGTTTAACACCAGTTTACTCATTCTTACCTGGTGTTTATTCTGATAATTATTTACTTGTACTTGACATTTTATCTTACTAATGATGTTTCTTTTTTAGCACATATTCAGTGGATGGTTATGTTCACACCTTTGTACCTTTCTGGATAACAATTGCTTATATCATTTGTATTTCCACAAAAGCATTTCTATTGGTTCTTTAGTAATTACCTAAAGAGACGTGTAGTCTTTAATAATTGTTTCCTTTAGTACTTTTGAAGAAGCTGCGCTGTGCACCTTTTGTTAAATAAAAATGTATCTAAAGTTGCGTAGTGATGTGCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCCTGTTTAACCTTAGCAATACGTGAGCTTT ++ +'/)1'..127=*8',/1+-*2-/1349222EDA58+1%%+)3211)*/2$(*+(.;B>8899972523(*+%$)+(41:7?@==215%7-$%%'+%'&&(-)1754)5&''';:5/=89<=87:;33'(<79;7?<18..6:@FF;6;,?;?@CJI?//.,-C;DDDFB;70,$3$$(-/038535=;;>569>8;>@@IE?45GB9=359=9=C=>;<6;9FC<;;89)7A=?E>DD:06@78=90$)$68:@C=>:;AC,,8>??B=:>?;C<>97536>:>/;GGC279:7796:58:9:DK?HC>79;?=;@BC>:=<'/-6?=?;>=9?9@?9@A1'==B@B>B@>>01/35CDAFC@@AC098<0?-,=3-::8BDFJ@@B8EC@8655<:6++.A@;?@>?7740*))++/056('&&%%*' +@SRR11410539.2215734 2215734/1 +CAGTATTGCTTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAAGCGAGGAATCGACAGCACCTTAAGGATCAGTGCCAAGCTCGCCTAAGTCAAAAATGATAAAGATCGCGCCGTAACTATGGCCACCGAAACTTTATTACCGTTCTTACGAAGAAAGACCTTGCGGTCGCCACTGGTATTTCGCCACATGGTCAGGACGCAAGTGTCTCACCACTACGACCGTACTGAATGCCTTCGAGTTCTGCTACCGACTCGGCCATAACATGACCATGGTGCGGTTCGAGCATCCGAACGTTTGATGAACACATGGGGGCTGTTCAAGTTGAGCCAAAACGCCTTTTCCAACTTCTACTAAGCCACAAGTGCCATCTTTAAGATGTTGACGATGCCTCAGACCTCCTCCACGGAGTCTCGAAAGCCACGGCCGAGCACGTCGCGAACCTGTAAAACAGAGGATGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAGC ++ +,%)''%%%$&'(%1;<>8984-,.0--1)-5,,5EKC25'0,.--3255(+$%$'1**-0<=8;>B+9%1,6868../B;3=6@FAF@A?5<::>%%$0.)'$%*('$')3(:89?@>CA@@,&),>;:%-9;<@>@;C00@@9;?<<@CB:;>@E7A;<;%+<;=<2+5/>%&7%'2%%&5=>;@&5556520+4+*)+.:4/<=@A/A<;==?8GCC?C?AEDC<;1;479$3300(*)*78::(=2/>:;<<@@C>9-69:?;<;(1:%-&'++*@;=7@,7CC?@D?;02&' +@SRR11410539.455079 455079/1 +TATTGTCTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACAAACTGCCACCATCACAACCAGGCAAGGATTAAGGTTAGATAGCACTCTAGTGTCAAATCTACAAACAATGGAATTAGCAGGATATCTATCGACATTGCAATTCCAAAATGAGCGCCACCATCTGTGTGAATTTGTCAGAATGTGTGGCAGAATAGAATAATTCTTCTATTTTATAAGCTTTGTCACTACAAGGCTGTGCATCATAGAACTTCCATTCTACGGCTCACAGCTGAGAATACACGCTTAATAGCTTTAGGGTTACCAATGTCGTGAAGAACTGGGAATTTGTCTGCTAATAATGCAGCTTTAACAACCATGTGTTGAACTTTCTACAAACCGCATTAATCTTCAGTTCATCACCAATTATAGGATATTCAATAGTCCAGTCAACACGCTTAACAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTCTTTAACATAGCAATACGTAACT ++ +#%(*%&#&17C--&8DEA;A9988;>A<=/=A@?=,.+0+96/'&/1574114.8<@;CBCC?GFBLHDEF5@>;:9577FBEB9&'=;3>?8(*(0$6900+;=7/1:*5&/8375*+1>97<9?9746++/064428$767537=85?128:/(('(&0:7?76=>DE=:0)/ABBGEMD>:859557DC@DEBFF=99,79A=DBB;:=::??9BB9:>?@7>C<@?EIHA=>AB?;E=@D@,.1$%43954/,--/+(#%7;>9@==>$<<-BEBB?@88*-$%&35;;==CA@BBA@>0:.@9=6684?8<>+(/+&&&&,-.05/>@;98795373*- +@SRR11410539.1928163 1928163/1 +AATTATGCGCTGATTTCAGTTACGTGTACTAAGGTTAAACAGACGACTAAAAAACGGAATCGACAGCACCTTCATCAGATTCAACTTGCAGCGGCATTGTTAGTAGCCTTATTGCGGCTCCTGCATTTTCCCTCTCCATGTTTAAGGTAAACGTGGCTGCATTAACAACCACTGTTGGTTTTGCTTTGGCCTTCTCCACAATGTCTGCATTTTTAATGTACATTGTCAGTAAGTTTAAATAACCACTAAACTATTCACTTCAATAGTCTGAACAACTGGTGTAAGTTCATCTCTAGTGAGGTTTGAACCTCAACAATTAATTTGAATAGTAGTTGTCTGATTGTCCTCACTGCCGTCTTGTTGACCAACAGTTTGTTGACTATCATCATCTAACCAATCTTCTTCTTGCTCTTCTTCAGGTTGAAGAGCAGCAGAAGTGGCACCAAATTCCAGGTGCTGTCGATTCCGTTATGATGTCTGTTTAAACGCCCAACAATACATAAC ++ +$$%&$$$$&%'&&(,,21-672,&*(.)7=342@FB=>0/%&&+&&&(/11.51557?B>@?A@CDCAABBCB;5A>;?A@532;=5=A?;(2$&*.)--1669:BCADC84,*%'5(($&(/+'+(161,&%8:..:78**()$&&('(.,-,-#$+0255>>F>@<@;925?9@@CBB89>3?'&3447=9:>@834?>88<=85C@ADC:;B@=B@;BF??@<>=553:GF>?DD?IBBDMCELAE?@CD0.@98=DC/;CD718,&&(')5003;=<;=9;:&-772;;>??=ADEE=&('')&&$&%%**10470+.+2%$$$((,.,+*.*,*)( +@SRR11410539.709951 709951/1 +GTTATTACTTCGTTCGGTTGCCTTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTTCCCATCTGGTAAGTTGGGGGTTGTATGGTACAAGTAACTTGTGGTACAACTACACTTAACGGTCTTTGGCTTGATGACGTAGTTTACTGTCCAAGACATGATCTACCTCTGAAGACATGCTTAGCCCTAATTGAAGATTTACTCATTCCGTAAGTCTAATCATAGCATTCTTAGTACAGGCTAGTGTCAGCCTAGCGCCAGGAGTTGTGGACATTCTATGCAAAATTGTGTGCCAAGCAGGTTGATACAGCCAATCCTAAGACACCTAAGTGGGTTTGTTCACATTCAACCAGGACAAGGCTTTTTCAGGTAGCTTGTTACAATGGTTCACCATCTGGTGTTTACCAATGTGCTATGAGGCCCAATTTCACTAGGTGCTGTCGATTCCGTTTGTAGTTGTCTGTTGCCTTAGCAAGTACGTAACT ++ +(-///63=?@?8G4<',12#$%$%&2825<67/C?=:=&067:;A=>?9A<=83-7,@=>DH@;IHG:=G845/29@=5660/7.3%&,/=BA;::?<99<955,)(($&.4<11012..9?;=?))*BCE:>?A7:?24**)+(-*+/'%%:@@5,:;6'':2331-)/.)%5$.23669:961:996500-<&:540675+888?@HG1',,,$%)',-:8;779;:93:*(+$%&,/.,,(,+*-'(&)'&&&$$$%%%$'$&&#$)*+%%056'29<9A=@7<53456>>8;:A:?86$((32''''5?@?>;798==:*+++-734A:<>EA=()(&$(*(:?1<81)2'1,>-/(+%557.&'*%%((((&1,/,*40::>4AA<@<<:46<<>74475A7366:33''&'**%(<>A@;/++4+556<>?@7'26;;<)&)1*3%)))&-/####&)"%$%#%)/442/(, +@SRR11410539.430821 430821/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCTTGGTACGGAACGTTCTGAAAAAGAGCTATGAATTGCAAGACACCTTTTGAAATTAAATTGGCAAAGAAATTTGACACCTTCAATGGGAATGTCAAATTTTGTATTTCCCTTAAATTCCATAATCAAGACTATTCAACCAAGGGTTGAAAGAAAGAAAAAGCTTGATGGCTTTATGGGTAGAATTCGATCTGTCTATCCAGTTGCGTCCCCAAATGAATGCAACCAAATGTGCCTTTCAACTCTCATGAGTGTGATCATTGTGGTGAAACTTCATGGCAAGACGGGCGATTTTGTTAAAGCCACTTGCGAATTTTGTGGCACTGAGAATTTGACTAAAGAAGGTGCCACTACTTGTCAGTGCTGTCGATTCCGTTTGTAGTCGTCTGCAACATGGCAATACGTAACT ++ +$,,464666<>I,-%9=<3<;=:7;8?9&'7@CAAC@:,,4*675.&;:<<4--6<<691,%:6.??G46310:<AA6:C-BCF98??C59668JH4&*CACB@@A=:;@&:'):CDE;<=BJC=AABKKHD97:79@=@/.0FGCB=3:>;;<<8''=5;AA44/$$(%&++3*$$1$$2&&(;88B<=D9+2+9?E./;=8:?6563)>;CAA<@9DG>?9=;A;;9;<63))&'%$&.<>(,)8>BGOKF-BD>@70AA>>EF@=''0DGFFC@3=C5>?=<7797@=999'/0,0<:>;A;.*;AA<4:H<827:@BBBDH@E:?>004D?@AFCBCDB=@=9;C??@-C9:A<<;A>?><@:><:;:>4@/<4<=<=A<=45<=:2?<<>>9@><@5::@CHGBHJF9/)>.>@>B6;14959846,+/((A8;B;=:?A05DGB9=45)>?:=<113-058DACC?66?;+%,(&.>=?;568:8:<<773.,@,5?:6,,('//75<7:AC=>==@=5,-38;ACGK@;5,,657/94DBF=?9888795>:=@B?=676>=47=<=(884/./-*$$$/&'%'-'8=;0*00)79>;AB=@:>BA=;=9:<=0%20/6,%(35AAC>9=42@=/0?B>78ACJ=:G;DFA>=443A>@@=F9:<0/3=@DCD:6EEFLB==7;:C@BJ<49:>A:+6$8638;<@?:C1<;:FFD@966--%.$/4';22>;7551237625$'(-87AEB>>9>=@=66,$$,'45=25:28+153A67*)*%3384/0/=BEB?;?A?99:5/.((76?DGDA;<.-,794;3;;>=687JJF'A>467,,-%*->=@AF?=>A>B>:<97;5@A3-./%1(185((B<=C:91C==BE@BEID/0,,8<:;8.B22687+9=?@F?,3<=<656>>A89<67/'<<@%505:90A,3H88-5/<3976/-A9;$>;AIFC/)=9DF@BIB686AEGDF99==9AA9:AD;;1>ED&::B>@M<1124862&B<<;68@A??;?@B:@@LDIB?=:<=/%1)&'(/00/0-/766:;59-'),5090?E;2B01=A;,@EDEE92488:9++:GGI?5154:6512.762&&()'+*+,//+#%&' +@SRR11410539.1713242 1713242/1 +TGCGGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACACGTGGTGTTTATTGCCCTGACAAAGTTTTCAGATCCTCCGGTTACATTCAATGGGCTTGTTCTTACCTTTCTTTTTGACCATTTCACTTAGTTCCATGCTATACACATGTCTCTGGGACCAATGGTGCTAAGAGGTTTGATAACCCTGTCCTACCATTTAATGATGGTGTTTATTTTGCTTCCACAGGAAGTCTAACATAATGGAGGCTGATTTTTAATTTACTACTTTAGATTCAGAAGACCAGTCCCTACTTATTGTTAATAACGCTACTAATGTTGTTATTAAAGTCTGTGGTACAATTTTGTAATGATCCATTTTGGGTGTTTATTACCACAAAAACAACAAAAGTTGGATGGAAGGGTA ++ +$$)$&-0/.,,.,+043.1<>B=A>)959%7:;ECIBE>FD?58'.5=6823-<;227-43%6<92121328>/2*.4))4*%8%+,/099>47,*$#%$#%%&,3732'&'%%*&$(()%$%#$$)++#$$&&$-./-0;:7<<<63*(68<;61;=/640.8:88;:56%3-*+65067:@>@?45GFA@9:;<8/345890&*%''728:>:;0335?B4266'*''(%'%)+06-23;1132,$($+.1-&%B@88/#%#%.+-/337@4+0&20-(&&%,*&,00687-:8689579379++*,,,4>H??A;<$$AC9;?=?@AC@4+/,06,.(&%'&&.JE>B>A98845A@EBB<46975=?GEBA?1,-(9:<544**5:97.427466407('($$/$ +@SRR11410539.1255481 1255481/1 +CGGTGTACTTCAGTTACGTATTGCTAAGGTTAGCTAGGAACGACTACAAACCGGAATCGACAGCACCTAGTTCCACACAGACAGGCATTAATTTGCGTGTTTCTTCTGCATGTGCAAGCATTTCTCGCAAGCAGTTCAAATTTCTTGCTTCTCATTAGAGATAATAGATGGTAAAATGTAAGGCACTTTTACACTTTTTAAACGCTGCCTCCTCTACAGTGTAACCATTTAAACCTGACCCGGGTAAGTGGTTATAATTGTCTGTTGGCACTTTTCTCAAAGCTTTCGCTAACGACACCGGCCTTTTGAGCTAAGGTAACCACACAGCCGGTTAAAGCGCCTCTTGAACATCACTATCTTTCTTTAAGAAAGTGATCAATGTCCATAACAAGGTGGCAGAATCTGGATGGTGCTGTCGATTCCGCAGTCATCTGCTAATACGTAAT ++ +-$%&&#$#%&-%<%-*.)&%&'&''$$.3-+%%$$$&&&-;8:9;69:7-%0(+$*1<<><<;?.:92,9?;;;1-8?@A@/-<8<<>?DE=>H<>=CB<=@77@=DA=**)2+<35.85:=;:46.3(%'78:?(8''7EGIDMF6=@A;C=5503)$$2,***/.6>686$'&&$$+45-62346665331:@@A>799/4,.92*)069@><=769<=;66<7>?AE<>3965?9D72'*'%'*(78<++*,%'&*6464447%(2-566@5>13,-'+'')),%%)&&(&#$')*',%($$##&%&$$%%,.(**()#'"%$'$0&)3667.%'$&&(8455.(',(5)),(.23::5=><560(/1180.,.',,,*,;8;77;45*,<395<0077=:3420%)30-..79?<=;23%+-163)03&$#$))&%($$%%$ +@SRR11410539.2207520 2207520/1 +CAGTATACTTCGTTCAGTTACGTATTGCTAAAGGTTAAACGGGAACGACTACAAACGGAATCGACGGCACCTTGCCACAGTACGTCTACAAGCTGGTAATGCAGCAGAAGTGCCTGCCAATTCAACTGTATTATCTTTCTGTGCTTTTGCTGTAGATGCTGCTAAAGCTTAAAAGATTATCTAGCTAGTGGGGGACAACCAATCACTAATTGTGTTAAGATGTTGTGTACACACTGGTACTGGTCAGGCAATAACAGTTACACCGGAAGCCAATATGGATCAAGAATCCTTTGGTGGTGCATCGTGTTGTCTGTACTGCCGTTGCCATAGATCAAATCTAAAGGATTTTGTGACTTAAAAGGTAAGTATGTACAAATACCTACAACTTGTGCTAATGACCCTGTGGGTTTTTACACTTAAAAACACAGTCTGTACCGTCTGCGGTATGTGGAAAGGTTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTCAGCGCCATGAATACGTAACT ++ +%#$+)+&$02135+.&.9;650,((+68;=>%,=76*+)2$(*)&5<=>;249;;827950<=@I-5GHBC@A10.0462@?A><=D5857/5=155)*))&3$*;(44@G?>=E@A@ED79DABEIB26+/A;.,9;5/37/38>EF@..@BGG?CE<=0:GJ@@:=ADE?A<1<=4<4>@,DDB@F<@CA?;BGD<A;?BD@<=@4>9:@==<:;:-.)869654>;=5.=4=>,,<4=AJI?FFGAM4FJ<&.0<+,8?D?:1/446976788;DEC56-*+->>>A??8*1&&%)7:@IHEB912-$$%;=;>491<698<<<<==@;9:>/:'-01&')6:@;=>EEI7/783-&&+'%%''$%%/#$%##%###&(('&&"# +@SRR11410539.902025 902025/1 +TATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCTTGGTACACGGAACGTTCTGAAAGAGCTATAAAGACACCTTTTGAAGTAAATTAGCGAGAAATTTGACACCTTCAATGGGGAATGTCCAAATTTTGTATTTCCCTTAAATTCCATAATCAAGACCTTCTATTCAACCAAGGGTTGAAAAGAAAAAGCTTGATGGCTTTATGGGTAGAATTCGATCTGTCTATCCAGTTGCGTCACCAAATGAATGCAACCAAATGTGCCTTTCAACTCTCATGAAGTGTGATCATTGTGGTGAAACTTCATGGCAGACGGGCGATTTTATTTAAAGCCACTTGCGAATTTTGTGGCACTGAGAATTTGACTAAAGAAGGTGCCACTACTTGTGAGTGCTGTCGATTCCGTTTGTAGTCAAATATGTTTAACCTTAGCAATCGC ++ +#$$&%*'./2::G460>B;0=6@::?@@DBB(HGFIL@:22534121()23*4),)+462-(%6=?BAD..@AB?.7@FCCKD>ADJIIIF54..199=@<>I4FA=BA9;72-<@DGJDB7L=9/67:)&=3:.,(&&009;9:;?:A623.(.13',0*,+%'%/0..36<==;8:=52$%($(3+:8((00>47FKJKH;1-.1B<=436<=AMKDECDC7.=69:4'+*,&67@9B@@??>>/:=?EBB<-,'43<:1&''(46<>CDUPCCA8>@3,5,('.(011891+?-6**=++=A:575932=8986=4GFJE78@?CEK?@GEC@@A4<22*,.6C99?,+4<3@CB9FGCKKDB4=@A78+,.*-87.46:?>DJP/%.123693>;2))*78595BDDDAE>AABA?:5(34(=>=4+*<>3(-,'.557710.+(*,05:*6@2;=98<=====@G@68,.*(&&)11%23*.**9&-12&&(' +@SRR11410539.1375574 1375574/1 +TGTTGTACTTCGTTCGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACAGGTTCATCTAAGTGTGTGTGTTCTGTTAAATGGTTATTACTTGATGATTTTGTTGAAATAATAAAATCCCAAGATTTATCTGTAGTTTCTAAGGTTGTCAAAGTGACTATTGACCATACAGAAATTTCATTTATGCTTTGGTGTAAAGATGGCCATGTAGAAGCATTTTACCCAAAATTACAATCTAGTCAAGCGTGGCAACCGGGTGTTGCTATGCTAATCTTTACAAAATGCAAAGATGCTATTAGAAAAGTGTGACCTTCAAAAATTGAGGTGATAGTGCAACATTACCTAAAGGCATAATGATGAATGTCGCAAAATATACTCAACTGTGTCAATATTTAAACACATTAGCATTAGCTGTACCCTATAATATGAGAGTTATACATTTTGGTGCTGGTTCTGATAAAGGAAGTGCTGTCGATTCCGTTTGTAGTCGTCTCAACCTTAGCAATACATA ++ +$%)+7?;89,7:K7<4<9--787798;>440=<<>B88577A@B?@;;99+&),+-:;<=544:?CC=:959>JEB>ABC;=:B@:033>A;7711&(#%#&&*/C:>==;6)1?EE@F6=,7B?69*666923;7+-(135048A?:9CCBC?==@A1?KA;6@??(=E@<:.7()12'+&,024033KFJH?=?>4@BD>JMH./745?B3)BF=>;87:7+5(2@%@@AHG9=9<9AC>6<;;5*A@@?>@F<;;66-:+./30./)(0,.-(%$&69;;644@BDG55<@G@DE>09130?@94-,0%&,6:=>@DAJIE898@@BBB+:CD3.@=@?BE?=@DDEM=@>@339:0A;:1--59899<7CDB;AFD@B;7*/25;;@?>>.,0$'2903<1-:<<7@<:6?;6')((55221'+$%4740'15--0-+)($ +@SRR11410539.643475 643475/1 +GTTGTACTTCGTTCGGTTTTGTGTGTACTGAGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCACGTTCACCTAAGTTGGCGTATACGCGTATATCTGGGTTTTCTACAAAATCATACCAGTCCTTTTATGAAATAATCATCATCCCACAACGATTGTATGTGACAAGTATTTTCTTTTAATGTCACAATTACCTTCATCAAAATGCCTTAAGCATAGACGAGGTCTGCCATTGTGTATTGGTAAGACGTTGACGTGATATATGTGGTACCATGTCACCGTCTATTCTAAACTTAAAGAAGTCATGTTTAGCAACAGCTGGACAATCCTTAAGTAAGTATAATTGTTTCTTCATGTTGGTAGTTAGAGAAAGTGTGTCTCTCCAACTACAAGTAAGAATCAATTAAATTGTCATCTTCAGTCCTTTTCTTGGAAGCTTGTATAGGTGCTGTCAGTTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +&3433/=?A=?D76%**-((*31(36430&&@PJIN=91518=9=>BCGG>9+055+50*(,165;<=?>BC;?GLGM586/.EE?93@2:871##$-.+,23*%$+388@<<23-0=D:D8D<;//,+*+$.0378=+0&47/?;==ABCG=8B97:9',.%,+488@@?<=:B>;;=>C@A;?CAA@@F?A>A<<>=99>;;2>1EG:354EC0-.,=<>;=?CC;7288995>BB<@E=AE:<>AGD=8425.9?6695,+''&*'((777?85/0(:-.1&7/?EDBEDEBBB2,/<<>=4&%*337679698<:>441$$$$$&%'%,=667.%'(#25--&/2@7D>>972554799853+.*,%$$//:>?@<'.% +@SRR11410539.1980880 1980880/1 +CGGTAGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCTTTTCTCCAAGCAGGGTTACGTGTAAGGAATTCTCTTACCACGCCTGTTGTGGCCTGTTAATTGCAGATGAAACATCATGCGTGATAACACCCTTATAAAACATTTTAAAGCATTGAGCTGATTTGTCTTTATGTGCTTTAAGCTTATTATCATAAACCAAAAGCACTCTGGTGTCAACAATTTCAGCAGGACAACGCCGACAAGTTCCGAGGAACATGTCTGGACCTATAGTTTTCATAAGTCTACACTGAATTGAAATATTCTGGTTCTAGTGTGCCCTTAGTTAACAATGTGCGTGGTGCAGGTAATTGAGCAGGGTCGCCAATGTACACATAGTGCTTAGCACGTAATCTGGCATTGACAACACTCAAATCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTGGCAATACGTAACT ++ +/$$)$''%$72EEHLI>@=G<@D;;=>=>/:25265>@H7G5CE8/98?<@<=-5==>>AA702;;BDB=9:?991DB?=B>@A>6%:64>9;=<=D?>@20;:53&&,.$%1A-EIKFLBDGJGAFEE<;HE?BAILKAADJB>E66B=@>?/,/>>:,09A;87(&*9:8B00==?;?B?=;50:>467@<&*..;>ABCB;;>?C?@CCBFE;=:=DF?>:@120:>><)D@AA><67;;C0&(1(=89<;;:-005$$49:676;?>6FHE-.-1>/733.:C?6444=ACFG=>=CA6D4D4--.;6;320C5465$#%8:?44@FEA@5666=67+-DBED1-CCHH?38?NLMCCEA>@<31+.*/*9333867:90;255930644:;:6@>@,'&0.9481:>>917;384A67DBH@>>>@647?AAIGE:@CCGEAG@65AC=?AECH?::,),$%-0+12/<51+1()9@;D>GFD@A4F?AG?3($-$#*,-;9KGEGGCDADDWDC@BE11<>?<:85>?=<;.377ED:'(>>>-><=>:3>@1('45/0?A942-/.,>?BBD;<4%*$%,++1,,,1,4687@AB?@>D>B@>@;7<@BFD<@AHAB;AA:CC>=@>4443@6==1587439&-><<4/*5%584.3572)6A?LK=ED88@-(%&('.7<;A?B@;C=?%%,;C.<'2*+)*>>7>A@BG?B:5B8=(''*ADA@A;=*&&%+$009@>@?B78CGG793;77D>@76**4<>=EDKG=7>CI<@@A67CC?67*) +@SRR11410539.2471101 2471101/1 +GTTACTTCGTTTGATTACGTATTGCTAAGGTTAAACAGACGACTACAAAACGGAATCGACAGCACCTTAAGGATCGGTGCCAGAAACAGTCGCCTAAGTCAAATGACTTTAGATCGGCGTAATAACTATGGCCACCAGCTCCTTTATTACCGTTCTTACGAAGAAGAACCTTGCGGTAAGCCACTGGTATTTCGCCCACATGGGGACAAGGACACCAAGTGTCTCACCACTACGACCGTACTGAATGCCTTTGGGTTCTGCTACCAGCTCAACCATAACATGACCATGAGGTGCAGTTCGAGCATCCGAACATTTGATGAACACATAGGATGTTTCAAGTTGAGGCAAAACGCCTTTCAACTTCTACTAAGCCACAAGTGCCATCTTTAAGATGTTGACGTGCCTCTGATAAGACCTCCCTCCACCCGGAGTCCAAAGCCACGTACGAGCGTCGCGAAC ++ +(%%((*--9@6'-)*-01-<888967.(89>>?B@AAAADBBBOE./>B848'+5+&&'&--()'$*5)202/0/6=;<=>@=BHIAI;5/3$&('&$$##$..40+++*+89=,%8(0()=83:>>>>IB>;;-.>,:0543AB@>GKCF/89?==CCBFEC8=''$'68A623<$46E603)*,.146499<@AA=B:8<:=>?;2400)&(9:>AB<=37628.73967;>*71285:==.7((*')2BAA=BCC>;;@A@000.'))$-.364<:;61'0$#)&.(5128@E22835B9?>?DDBI>??@==-3**'*42;>A>6FDC-3@AB9=9:71235<:-A<=AE@),%%&%&)&&00)2A=@A==@8<>=<:<>@A9:;7<;8689A>%&9<:>=@88977..'5<40B=ABD=;;B.3.>>AB?A?BBA34<3?;:=5G>@HDDG4D?8:+'("$$&:=:.@?LG<<<888L580076683,((2$&-88:/?:;BBJ?3...40/05:=24C>AE<9F?9:&595/>@?>?>@:;?=A@=A=CDFBA>>=8=446956/48;:9/39=@A?D?@>'**,-;55;4:2)-68;%02(;;>;=7>8?9:F<@<>>::;:278>>:5*+)+&( +@SRR11410539.1228354 1228354/1 +CATTGTACTTCGTTCAGTTACGTATTTGCTAAGGTTAAAACAGACGACTACAAACAGAAGGATCGACAGCACCTTCCTTTGCAACCTGAATTAGACTCATTCAAGGAGGAGTTAGATAAATATTTTAGAATCGCCATGCCAGATGTTGATTAGGTGACATCTCTGGCATTAATGCTTCAGTTGTAAACATTCAAAAAGAAATTGACCGCCTCAATGAGGTTGCCAGAATTTAAATGAATCTCATCGATCTCCAAGAACTTGGAAAGTATGAGCAGTATATAAAATAATAATATGGTACATTTGGCTAGAGTTTTATAAGCTGGCTTGATTGCCATAGTAATGGTGAGCAATTATGCTTTGCTGTATGACCAGTTGCTGTAGTTGTCTCCAAGGGCTGTTGTTCTTGTGGATCCTGCTGCAAATTTGATGAAGACGACTCTGAGCCAGTGCTCAAAGGAGTCAAAAGGTCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTGCTTATTACGTAAC ++ +'$$%/3+:AD<>N21+4;;:8973249=?B/0-:>=,..*(&+&831.)%)01**&,&&*%220-<;FDFG<=E>89:CHFA-.GEDCA@?A:;89=2?@9AJ=5=@G==>BC>A?77=:9(4+8C;;**,,,5.>?>H99809&7*&&*2++*5???AF?@@CEEGHBC9?:>:AA?<=;C@G:CGML??4G(8@8HD@CADJGE22(<869340167><<3<;**,-/11-(39<76'?<=EC@>?<>;;9/0&%-%54+2;CD==>H3226A;0?06E:0-%%*&&&)&&&:,+2>@?:;96>ABA,1510)4/0)6):<5665036144<@::4-4,478==?6=<;?=>F%@66/3D>CF37CEB@77724?A><=/2<=EHI?EC?=<8032&+ACD>=EE/2658/;;;*'+3%%&4:@BBCD?A=DAGBCCB:>;9:8=>;@:90-//''(6>;9,/' +@SRR11410539.2220484 2220484/1 +ATCGGTATTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTATTCTACACTCAGGGACCACCTGGTACTGGTAGAGTCATTTTGCTATTGGCCTAGCTCTCTACTACCCTTCTGCTCGCATAGTGTATACAGCTTGCTCTCATGCCGCTGTTGATGCACTATGTGAGAAGGCATTAAAATATTTGCCTATAGATAATGTAGTAGAATTATACCTGCGTGCTCGTGTAGGTGTTTTGATAAATTCAAGTGAATTCAACATTAGAACAGTATGTCTTTTGTACTGTAAATGCACATTGCCTGAGACGACAGCAGATATGATTGTCTTTGATGAAATTTCAATGGCCACAAATTATGATTTGATGTTGTCAATGCCAGATTACGTGCTAAACACTATGTGTACATTGGCGACCCTGCTCAATTACAGGTGCTGTCGATTCCGTTTGTAGTCTCTGTTTAACCTTAGCAATACGTAAC ++ +%'.-1/+(+%,-228@9:3:=@B;AEEBD3,<9:3CLHAE7>//>;ABBC@CHKH@9=<=98>D@?@@=D@A?BB@4ABCD>:CBBBGB:=,'8@988=68CBB@@C@B?A=C@EB@BBGC?BDDD>'(976533;7(4.6'&-,245:;78==B9975,$*)&(((,099;9?4<=:<945...)/('28:7.3/,42-;=??E9'3<8:@D@@=84CECAA@B;:@54:;<8A<4,(((+,4ABC?C@@ACI46++CBEFCFC?@87:79D>C:??=A<6/%&88@99CB9@><::;BCBGEAB>:8751?CFFBEACACMI71*'*9>=9C?ABA98''8'.384=9>9==/58?@E>=39<<===;/39BAJLJGBEK<4838>4,09EGFFD>B=?<.69>IIN@DFD;:%1:999<=?=>>9300008,761''% +@SRR11410539.1892985 1892985/1 +CGGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACTAAACGGAATCGACAGCACCACACACGTGGTGTTTATTACCCTGACAAGTTTTCAGATCTCAGTTTTACATTCAACTCAGGACTTGTTCTTACCTTTCTTTTCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGACCAATGGTACTAGAAGGTTTGATAACCCTGTCCTACCATTTAATGATGGTGTTTATTTTGCTTCCACTGAAGTCTAACATAATAAGGGCTGGATTTTGGTACTACTTTAGATTCAGACCCGATCCCTACTTATTGTTAATAACGCTACTAATGTTGTTATTAAAGTCTTGTGAATTTCAATTTTGTAATGATCCATTTTTGGGTGTTTATTACCACAAAAACAACTAAAAGTTGGATGGAAAGTGAGTTCAGAGTAGGTGCTGTCGATTCCGTTTAACGTCGTCTGTTTAACCTTGTGCAGTAACTTT ++ +'#$''*'+--&,992-502.,)66:=9CF,,8>98;?54'('*'.115(,9<679::46763'*,*%%44;13BBA?;9=@@B@87.+&0203;T3;32+%4,71;=865DDDFDA8:;:9:3>:FDHBJBOA6@A?BC?BDA=CC;:=9;;@:;=@<>BA?>BFA:8DEB=/B*@24ABA:29@=>CB7A<=?BC>BDBJI423:32:'')&3>C2;=>@@AD?'8.%,.98:8LKJ??CJ=;C62EGHAA2?<7$$.%'%$%3366>>=?BABB=CE>=@>?>::C?<;8:))>>3CD?A?6811-4+)'3587CEKG=>?DOK;D@FC@=9;G@GGLJ;;>=FIEEFEBE?=>5@BDCD?8-.((89A2:;>8:BD;>5874DFAED4A@=1B/-,:AACCB=>?@EG>>,774%&&%%'5<>B:DA;01/-**$'$'%%%%)&''& +@SRR11410539.1230662 1230662/1 +CATTGTACTTCGTTCCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACTTTTGAAGAAACTGCGCTGTACCTTTTGTTAAATAATGTATCTAAAGTTGCGTAGTGATGTGCTATTACCTCTTACGCAATATAATAGATACTTAGCTCTTATAATAAGTACAAGTATTTTAATTGGAGCAATGGATACAACTAACTACAGAGAAGCTGCTTGTTGTCATCTCGCAAGTAATGACTTCAGTATCAGGTTCTGATGTTCTTTACCAACCACCACAAACCTCTATCACCTCAGCTGTTTGCAGAGGTGGTTTAGAAAAATAAGCATTCCATCTGGTAAAGTTGAGGTTGTATGGTACAAGTAACTTGTGGTACAACTACACTAACGGTCTTTGGCTTGATGACGTAGTTTACTGTCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAATACGTAACT ++ +)((,8:7>2AIIFIDA88>00%#%#%-051.1>?FBCAECAAB=22332116.1*%%0')+06-*$((,28;?DB22-*&-'(9=;B7GJ::AD?44,&&5<>H>ECCDA<>@6:=:DA==..:AA><<:=8'-ABD=<@A>BF>89<:A6,;$%%&418,56??EDHDF@=D=63))%%9:DCC<=9:7?866/3-943432<&12345@,,9;8->C?ALH2C'?=>@06/0*)5;;G;:FA40,)0457722/9;0CAD=8689;D;7*&1?@C9<=BJHIAC>BBEBAB9=<:AHC9:9210387;2200'*CEB=;((#% +@SRR11410539.1607630 1607630/1 +GTTGTACTTCGTTCAGTTACGTATTGTAAAAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACTCTGAACTCACTTTCCATCCAGCTTTTGTTGTTTTTGTATTAATAAACACCCAAAAATGGATTCATTACAATTGAAATTCACAGACTTTAATAACAACATTAGTAGCGTTATTAACAATAAGTAGGGACTGGATCTTCGAATCTAAGAAGTAGTACCAAAAATAGCCTATTACTGTATTAGACTTCTCAGTGGAAGCAAAATAAACACCATCATTAAATGGTAGGACAGGGTTATCAAAGCCCTCTTGTACCATTGGTCCCAGAAAGACATGTATAGCATGGAACCAAGTAACATTGGAAAAGAAAGGTAAGAACAAGTCCTGAGTTGAATGTAAAACTGAGGATCTGAAAAACTTTGTCAGGGTAATGGCACCACGTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATAGTAACT ++ +%24*76:>4=7K=82<>8103;=<;*6>@*'%(>JIDH?:B;AB>D?A=<>>4.236?:69888?@B?>7-)@?@ECC>B@+9BCD;5@8802&''-;<9>D9C>82'*$%'0564+(()$'**,6ADBADCDCBLMGCFD::<89H@=2*98<6;?JGFAD98.$$,1137=428/$$$'&$$+*#&&30>277+,,&''&&$%%&&&&%('&(%+/0,%$(')'167=9BLH?;45.:157;:9?@DB<45.0157A;@>FEDH6>:<70A<@)7&*:82(09++&'-,+.'%&&%%')0)0,28:=+<)(('362:68<>75<<8?<@;6*8-.18=@A88>=?@GK18E;*248()27<>79867:7:;=BB>>A86859?D>@A?=:608,&))%-%:;=3,:-C<ACGI;<8FFL?C26=<9;>/:5736>2.&&',50&, +@SRR11410539.2265575 2265575/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGAATCGACAGCACCTACTGTGTTATGTATGCATCAACTGTAGTGTTACTAATCCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAGAGTGTGGACACTTATGAATGTCTTGACACTCGTTTATAAGTTTATTATGGTAATGCTAGATCAAGCCATTTCCATGTGGGCTCTTATAATCTCTGTTACTTCTAACTACTCAGGTGTAGTTACAACTGTCATGTTTTTGGCCAGAGGTATTGTTTTTATGTGTGTTGAGTATTGCCCTATTTTCTTCATAACTGGTAATACACTTCAGTGTATAATACTAGTTTATTGTTTCTTAGGCTATTTTTGTACTTGGCCTTTGGCCTCTTTTGTTTTTACTCAACCGCTACTTTAGACTGACTCTTGGTGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAACCATACT ++ +''..8;9;=@85H=>:@ECHFEE<:ABCCBCB?<;7:9@$%???G???=;B:;?./<98A?::30'(><+/16,9((-:BEBD;9:=?DGDDCEG79HFCA;;94?@KHGDEE6<=122+*340=;:>AC?@B>?7,./8:<7:?@<=:;67@=J?7>?>A8CC@DIC?7-61E@?<>;999>?=>:>8899<<6B@ECPGALEAAB?B;:./2477/.9336:7884,)(.+''/1&4.46/.2BFDDCC-/$$#.+4?DB@-*)(()')+*',=;<<85::BLE9==@>/&6=?$%<;44;4/067=>@89CEAC9E@?C?I8=FDG??>864+DD?@4:=ID>989:=<@AAABEEF:@933*+$$%',)%## +@SRR11410539.2236911 2236911/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACAAACTGCCACCATCACAGCCAGGCAAGGATACAAGGTTAGATAGCACTCTAGTGTCAAATCTACAAACAATGGAATTAGCAGGATATCTATCGACATTGCAATTCCAAAATAGGCCCTACACCATCTGTGAATTTGTCAGAATGTGTGGCATAAGAATAGAATAATTCTTCTATTTTATAAGCTTTGTCACTACAAGGCTGTGCATCATAGAACTTCAAAATTTCTACATCGGCTTGAGTACACACTTAATAGCTTTAGGGTTACCAATGTCGTGAACTGGGAATTTGTCTGCTAATAATGCAGCTTTAACAACCATGTGTTGAACCTTTCTACAAGCCGCATTAATCTTCCAGTTTCATCACCAATTATAGGATATTCAATAGTCCAGTCAACACGCTTAACAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTT ++ +%$&'3630:09;A:A=>@@1<==:?B?C=>>%-1DD?B/,4019.-,+//479:5;6=;>><:A=DBGFKA?A@+6A9CCE??EBDD.<$;:>AB6,-&'%$%&./(BE4)+--,36<><:2)4=,'/'((6;?BB?ACHAC34*1,;>7986??<89@>=86:6A;<<0.,)(('.0/85:C:C>7@98;BBE>89C15D;<;8':;3:<23*3C+>)8<:6909=?>A@=CCA<@=66*((-351;0.9;:68=;<<4/*90/14/4)*.01(0''&&3:CAA7B5/;*,$$$%$-'$+*1:9:;22.(.157827AB@CAECGB>>85.00(*(('+'156;E<>B@?=5CEB;;836*,+2359:=23:72++3-./12?>=>@F=?H>FH>AADGEIE>@;<<9)+14==;;>@518?AABCFDGEEA@??=?A@33B;3+>79A/:62248:><<(:45;;>?AABGC<=>OKKD@B=8=>>A9;870 +@SRR11410539.1158374 1158374/1 +CAAGCGTACTTCGTTCAGTTACCTATTGCTAAGGTTAAACAGACGACTACAAACAAAATCGACAGCACCTCATGGCTGCATCACGGTCAAATTCAGATTTAGCCACATTCAAAGACTTCTTCAACTTTTAGAACAACTTCAGAATCACCATTAGCAACAACCTGCTCATAAGCTTCTTGAGCAGTAGCAAAGCTGCATATGATGGAAGGAACTAAACTCTGGGCTATAGCTTGTAAGGTTGCCCACATGTCCAGCATTTCTTCACAAAGCTTGTTTATGTCTACAGCACCCTGCATGGAAAGCAAAACAGAAAGTAGTGAAACCATTTTTCAAAGAGGCTTCAGTAGTATCTTTAGCTAAGAAGAATGTCATTGTGTAACTGGACACATTGAGCCCACAATTTAGATGATGATTCTACTCTGAGTTGTTGCAAAACTGAGAGTAAGACTACTGATGTGCAAGGTGCTGGTAGTCGTGTTTAACTTTAGCAATACGTAACT ++ +$$%"$%)*/05;A892CHGGJA6<9AC=CDIF;@GM;@;@GJDD08;;@KA=DDCB>FEHG?BC6)5?FD>HFB;;9?>>0?+3EECA?A49><48;8II@>640)+75BI@DG>@=.0%&.)24*))'%$#%&--5=>A@EE3ACC?=:;=-2EKL:?@B<<;GGHHBEBD35246&>HJOJ@C:<633=47=A;D>B?AB@ED)/$'*&%,3777457ABC>?7/GGA>0&>@B*,(*)?>?>@9@D@=<;;A@B?CCD5=8/2;:?753$$$)$&:55@:((11;AC?82>;><=0A?=73%&#%360%*1/3B::7:@6/997/*)&++-.&% +@SRR11410539.292614 292614/1 +TGTTGTAGCTAGTTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGGTTCTGGCAATTGGTGTAAAGGTAAACGAAACTGTATAGTTACCGATATCGATGTACTGAATGGGTGATTTAGAACCAGCCTCATCCACACTACAATTCAATTAAAAGGTGCTGATTTTCTAGGCTCCTACTCTAATATACCATTTAGAATAGAAGTGAATAGGACACGGGTCATCAACTACATATGGTTGATGTTAGGTACATGACTGTAAACTACATTCTTGGTGAAATGCAGCTACAGTTGTGATGATTCCTAAGAAAACAAGAATTTCATGTTCGTTTAGGCGTGACAGATTTCCATTATGATCTTGCAGTTCAAGAGTGAGCAAAGATAATAAGCATAATTAAAACAAGGAATAGCAGAAAGGCTA ++ +$&%%$##$$(',(+<83;D?4?ABD<;438<:1@FGGH3<77;0>CCF>>EGC;'(455<>?)':<=C8C>AEM-29<<;+-+0$%9-,67-+9B?B>:&&*:=@>9(')%%$./26=BA=BBDAA==B>BADA)*8>?>QJ;2'3,?8;06'(0F-,$..1:969@'%385..8111-)6;;9H4?K>(/(03A>;B?>@CBD?<;>=::72@?@?>AD=BBE:;GIC@E@2-#'-2++8:;;8=A?@EGAEEE@;:BCD/6@??+B?@D=.'.%$$$5;AE<848D948>>16*03$332)2+%>@<$=;9=A@@=9:A<%&&&/-:&'&/361-'2>>9+?9**,-22@HF?A@CBD@8;337:29<78:''AA<4:85' +@SRR11410539.2323656 2323656/1 +CAATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGCACATCAGTAGTCTTACTCTCAGTTTTGCAACAACTCAGAGTAGAATCATCATCTAAATTGTGGGCTCAATGTGGTCAGTTACACAATGACATTCTCTTAGCTAAAGATACTACTTGAAGCCTTTGAAAAAATGGTTTCACTACTTTCTGTTTGCTTTCCATGCAGGGTGCTGTAGACATAAACAAGCTTTGTGAAGAAATGCTGGACAACAGGGCAATATACAAGCTATAGCCTCAGAGTTTAGTTCCCTTCCATCATATGCAGCTTTTGCTACTGCTCAAGAAACATGAGCAGGCTGTTGCTAATGGTGATTCTGAGATTGTTCTTAAAAAGTTGAAAGTCTTTGAATGTGGCTAAATCTGAATTTGACCGTGATGCAGCCATGAGGTGCTGTCGATTCCGTTTGTAGTCGTGTGTTGTTTTAACTATAGCAATACGTAACTTA ++ +,$(*,++=@C@ALC929<7@:;<7=;65?>396<;D=?BCBEACF?=D<40C72A67:=97<@B>>A8.3*?*2HD;A66CCGBD8<24>7C>>B=B??@9>A=:<=<;04==@F69'()*+,'$-2;:;=>=<7:7?8>BE57,**.4-69BB30CB>=97,,/0.,099>?AA?AOGCFBCEKKFCG?A>>AC99??D@J=D=;::;=<:;<3;4:>>>DFB9=?C=>>;.4<,6-14>7:8D89A:CD@A=:>=6-%')+667;AA683686:9532?>@BAADD>@>>C@CA=?:66/0>8=?ABKKGIJDBDBC6>45%0-&&:>>:?6199A=;=-+1:--039EG@?CB??:111:BJHDHDEFD4+759:5)%*?CNLBDDK<@H@FC>KLGAHGIHDEDFED>?=B0598;-,=?:<5./4<::D?9>=9::8<7>:C;9B>8.&%&)'*.,::?>81+/*?A?@A922942()%&'( +@SRR11410539.44699 44699/1 +CGACGTACTTCGTTCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCTGGAATCGACAGCACCTAGAGTCCAACCAACAGAATCTATTGTTAGATTTCCTAATATTACAAACTTGTGCCCTTTTATTGAAGTTTTTAACGCCACCAGATTTGCATCTGTTTATGCTTGGAACAGGAAGAGAATCAGTGTTGCTGATTATTCTGTCTATATAATTCCGCATCATTTTCCACTTTTAAGTGTTATGGAGTGTCTCTACTAAATTATTGATCTCTGCTTTACTAATGTCTATGCAGATTCATTTGTAATTAGAGGTGATGAAGTCAGACAAATCGCTCCAGGGCAAACTGGAAAGATTTAGCGATTATAATTATAAGTACCAGATGATTTTACAGGCTGCGTTATAGCTTGGAATTCTAACAATCTTGATTCTAAGGTTGGTGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACACCCAATACGTAAC ++ +-(%#&&&8;;>>I>8,.38BE=JIJG<>;+,0>BBDF8;55?<:939@:<<8)))-&--8<@7969<;9510*6&&2---9///((,455989;98<<')/,,5689?A)C>ED?AGD5++.;4(.*/HD?@DBACC?>6?3239A6?B?E@=A:-'*5=ED>?,.7.=<@E-,(.,%)#%$+$*89<=;<9116/3+(2&'(49:;79<KKP>00/CDB@:978/=@B=?.<)7:=>@996/-124..30)(&&(.(+(68=;4;:A54-&,56;DACCI?@<<<<3;&%%;?=<;;+.);--65>>A>BEFI+D@@DGEHJ20569.1.69:<,&%%64=?=B6869FC<>8GD>A::BHGEIDNA>?<B@<>EA<<;?:;967>A@BDBC4?0FF0ECCBBFGH@I<3B@@F@;BDCCD?B@JHE>;36AABB@?((&%%---.6=B@;&%& +@SRR11410539.864290 864290/1 +CTGATGTACTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAATTTGGAAGAAGCTGCTCGGTATATGAGATCTCTCAAAGTGCCGCTTCTAAGTTCTGTTTCTTCACCTGATGCTGTTACAGCGTATAATGGTTATCTTACTTCTTCTTCTAAAACACCTGAAGAACATTTATTATGAAACCATCTCACTTGCTGGTTCCTATAAAGATTGGTCCTATTCTGGACAATCTACACAACTAAGTATAGAATTTCTTAAGAGAGAGTGATAAAAGTGTATATTACACTAGTAATCCTACCACATTCCCACCCTAGATGATAAAGTTATCACCTTTGACAATCTTAAGACACTTCTTTCTTTAGAGAGAAGTGAGGACTAGTAAGGTGTTTACAGTGAACAACATTAACCTCCACACGCAAGTTGGCGAGGTGCTGTCGATTCCATTTGTAGTCGTCTGTTTGTAACCTTAGCAATATAT ++ +)$&$%&/-11234?--&4+/*9:>A=@-4+.*2=>@C796:69885+**23*.%'&(.730>;BC?H=G?@>@J9:HM:AE8EJEFGE9,757.<3?99/90300?1++((,/,,&'/C+83?HHE??J=>@<=BGD?FB?<=@?=;BC<=B@C@AB=GA9H6C7EHJGA?=9:GKB7>B@E>>5--/&',&0+0/7;@@@@>GK;:G=?F?$''6(89'3::=)-0139?:;A?>@GC@<5=1,2979735,/):=+8)*,(+A=:=''02&&'..?77<68=66547>8@<==:<93-)677++0,,,&'-(%&$(,2:993**+%$$%&)+'-4-1025969;D==AF=>BAEGF?>??ABBEFI>DC10,/5<;69;>@@AB9(-/$978)6;;FBB=?8>@&&,:34@556=<488==5)1.(4/.,;<(((,-9?<:==@9;11/4).,36=??=>797:>):<96'(%%%)&&&))/'$-0'% +@SRR11410539.98118 98118/1 +GTAATAAGCACAGTTGATTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCTACAGTCATGTAGTTGCCAGCTTTAATACTACTATTCCTTATGTCATTCACTGTGCTCTCGTTTAACACCAGTTTACTCATTCTTACCTGGTGTTTATTCTAATTATTTACTTGTACTTGACATTTTATCTTACTAATGATGTTTCTTCTTTTTTACTTTCATTCAGAGTGGATGGTTATGTTCACACCTTTAAGTACCTTTCTGGATAACAATTGCTTATATCATTTGTATTTCCACAAAGCATTTCTAATTGGTTCTTTAGTAATTACCTTAAAGAGACGTGTAGTCTTTAATGGTGTTTCTTTAGTACTTTTAAGGAAGAAGCTGCGCTGTGCACCTTTTTGTTAAATAAAAATGTATCTAAAGTTGTGTGTGATCATGCTGGTGCTGTCAATTCGGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTA ++ +)+&'&%%))()%.')(%()**/,+,168>;;(-66@BC;<8;>CCFFEEFG9<367@=<991+&$'-425<926*83<==1+&%%%134010..96*/7::%(*2<;?:989<=-,-+)%122(%&238<;:--84@68D@BFB<=@AFHBGFI48AD>?8543+(*++4335578;>@@@9;><56>@CJHC=@8:5E;@891%8===41&$')'%&11++)();9;=B,0<:6')<9C<;C89D@9%%%%%709;5C4B?BDKCCAECH7;--;<,7AA;A:;8:5;4(=AB2+5<;=.),0++**%')011%'98371:576>4))4407AAD4>C;B=::-5-/-++%'#'#%$$&%#%(+1/6;55;#�>,2FF@;?B=;;46:17;9:89;;;2A(.:80/*&($ +@SRR11410539.97901 97901/1 +GATGTACTTCAGTTTCGGTTACACGTATTGCTAAGGGTTGGCAGACGACTACAAACGGAATCGACACACCTTGCCACAGGTACGTCTACAAGCTGGTAATGCAACAGAAGTGCCTGCCAATTCAACTGTATTATCTTTCTGCTTTTGCTGTAGATGCTGCTAAAGCTTACAAGATTATCTGGCTAGTGGGGGACAACCGATATGGTGTGTTAGATGTTGTGTACACACTGGTACTGAAGTCAAGGCAATAACAGTTACACCGGAAGCCAATGTGGATCAGAATCCTTTGGTGGTGCATCGTGTTGTCTGTGCTGCCGTTGCCACATAGATCATCCAAATCCTAAAGGATTTTGTGACTTAAAAGGTAAGTATGTACAAATACCTACAACTTGTTGCTAATGACCCTGTGGGTTTTACACTTAAAAACACAGTCTCTTGTCTCAAGGTATGTGGAAAAGGTTAGGTGCTTTCCCATCGATTCCCGGATCGATGTTTTAACCTTAGCAATACGTAA ++ +)#&''%**,&%+690+%-9:3')6.0/;=;;=:;)/$2-(+))&*)2235..34'-%)%<86,+&%%%--//'&&$$%-,'%)**;-9:79.2/*+/.2116/0+2&&+&-%10.-0;:;:D@JGE>5@9;=IH<;9?57'<3689A98,-(&*+/(,$%,'//5590<6513057=9-/<;::9=<:81,&$,+2')%0453///./8063.<1:6;18'&$&(%$'(*+1-<*239:?>KR6&'77))553,)6:9:92,-543+/%&((('%&)+9=ADCBB?;2*869=HGJ>349((+,-983441-;35+&&'&++'$$#+7;:33==>.35(9=<8-,/+*').3$&%+.26224())$&$-.$$-$+,0-&'&'%((*.3399210&' +@SRR11410539.822872 822872/1 +CGATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGCTGTTATGTACATGGGCACACTTTCTTATGAACAATTTAAGAAGGTGTTCAGATACCTTGTACGTGTGGTAAACAAGCTACAAAATATCTAGTACAACAGGAGTCACCTTTTTGTTATGATGTCAGCACCACCTGCTCAGTATGAACTTAAGCATGGTACATTTACTTGTGCTAGTGAGTACACTGGTAATTACCAGTGTGGTCACTATAAACATCTCTTCTAAAAAACTTTGTATTGCATAGACCCGGTGCTTTACTTACAAAGTCCTCAGAATACAAAGGTCTATTACGGATGTTTTCTACAAAGAAAACAGTTACACAACAACCATAAAACCAGTTACTTATAAATTGGATGGTGTTGTTTGTGCAGAAATTGACCCTAAGTTGGACAAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTAACCTTAGCAATACAAT ++ +$$%'&-,;>><?:922,-0%%(?>0)75865033A<>>>=::A?7867:=>DA:-048851+.68===<=>CC@@ACABBECEBH;EA5=6.@:?8-0%.36,/0.1&)5;7@;=6<:<=-42315:<=?>>A?*(:,/687534472)5;@C7('',CBG?FGFDFCD5.72067==;>=E??)?>@DA=@<2=??EF:CD>7;41>AABC;9@B:@74;<5,=%6189C:@477.0.,)/2523.0.4;@C;=>?5877(-.744.A(>?7,),--2C8777<:>?;))2$/.()92./103499@?CD?<79;+1@*4310*;;2,0'?*0)*,.7:FI?HDRKEDI=HG1*C:KE>411@AAB=:>JK?>>B@JD;>BCGB?A<*+@6',7A@E=7%1''88@?@CAA>=/><8BA242.*+19@?@?==ADGJA:;4>932>295203+,'4:?AAA@B=:5<*-%(%+#$%)'+,%17''0=5;=?79$$/3864*('--+/#$,(68:9:9:79;?@:?DA.8+,%-5<7>=>8-1:3:685FI7?;@;>G>=>33;==;<=+<=::0?+47E?=>-/,''##%%)+-..::/010''''3443;A?<<7CC8&'*$$+313'534-9;:1,4)%)3769,1218:89>A>FKGDAEB@??ACBE9C;<-24;>B<>AA?@<=9=??:$'<83-(.4;9969,,9;?501820)/'*++,,9855%(&&,**,.,+$(,43+%,+)0&,9;;;6)&)69?0'4(7;969&(//7DGG78/3?=58%$?78:28;?>61/.%%'*+*()%%7066AEIC@@BBA>ABGDB;@GA7<449<;:80*%*-734?02*4$)+,>7<@>?@C@@9)*'2&''(CD@<<.5512664-&,9;JC>?>?85-.$""%(%(%$# +@SRR11410539.1370297 1370297/1 +GGTGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTTGCCTTGGTGATATTGCTAGAGACCTCATTGTGCACAAAGTTTAACGGCCTTACTGTTTCACTTTGCACAGATGAAATGATTACTCCAATACACTTCTGCACTGTTAGCCGGGGTACAATCACTTCTGGTTGGACCTTTAGTTATAGTGCTGCGTCTAAATACCATTTGCTAATACCAAATGGCTTATGATTTAATAGTATTGGAGTTTGCCGGAATGTTCTCTATGAGAACCAAAAATTGATTACCAAGCAAATTTAATAGTGCTATTGGCGAATTCAAGACTCACTTTCTTCCACAGCAAGGTGCGCGGAAAACTTCAAGATATTGGTCAACCAAAATGCTAAGCTTCAAACAGCATTAAACAGCTTAGCTCCAAGGTGCTGTCGATTCC ++ +%%&&(+/.45=89B@<7:FFEECCHEB::>:=>@6@:=:B<>98)4':=:<7A?3/1///.:96*&'.%%--,%&&,-0+%*,1907,,-,&/0E7C369..).22347.$+%)#%$%&&%&%)$+&)268868;9>>G9:3&3---33385())))/.$$#%&79*-%+"$'*,$/&*(%#$#'+6()==;727+684.**,-77,-()061/-/,+'&$'(*9@BA56($3531957:*+&%&,26@:<>>9=74367),<=35(*5%4*+(&($$$$.3-,06=?4,351)%%$&159A4485584.2-+36&& +@SRR11410539.1893571 1893571/1 +GATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAGCGAACGACTACAAACGGAATCGACAGCACCCTCTTTTCTCCAAAAACACCTTGGGGTTACGTGTAAAGAATTCTCTTACCACGCCTATTTACATTCGGCCTGTTAATTGCAGATGAAACATCATGCGTGATAACACCCTTATAAAACATTTTAAAGCATTGAGCTGATTTGATGTTTATGTTGCTTTAAGCTTATTATCATAAACCAAAGCACTCACAGGTGTCAGCAATTTCAGCGGGACAACTTTCGACAAGTTCCGAGGAACATGTTGGACCTATAGTTTTCATAAGTCTACACACTGAATTGAAATATTCTGGTTTCTGGTGTTGCCCTTAGTTAGCAATATTGCGTGATTGCGGGTAATTGAGCAGGGTCGCCAATGTACACATGAGTGCCGCGCGTAATCTGGCATTGACAACACTCAAATCAGGTGCTGTCGATTCCGTTTTGTAGTCGTCTGTTGGCGCTGCAATATACT ++ +&#'%%%',018C-5-:8;7796779212,-*<,(%%##(%%'004483798;/138541.+*5;>==>=6<>G?;4&5??;<5-),0,,(*781-/,);-2./&.&00569><;6>?+@?;:6%%%%#$#$%$./:;??:?33/2+-..4771&&;?=685314:;=A55=@==>124;AAC%*%&%%)213238885:;;6/117:5884AC87=3/+%('+&%%+.015365617878.782:(8;A<49...,*%$$),/,)'&*)+,'($':034*++(#%'1,/.*60-&&--&&&)+$(++))+-/'(%&.(,+.7?<6;553;9350/97896..:>.*)%&%042.578--/=87=B>;964832>77.&,(-8A@CB;7>EBC=>?>;:F>4125:=8:<88.,'#%$#*).+,+'&'$$ +@SRR11410539.1115088 1115088/1 +CGGTAATGCTACCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTAAGAGTCTGTTACATTTTCGTATAAAGTTGCCACATTCCTACGTGGAATTTCAAGACTTGTAATTGCAACTTGTCATAAAGGTCTCTATCAGACATTATGCAAAGTATGCCTACTTTTGCTCTGGTAATAGCAACAGTAAATCTGTTTACATTACAGAGTGAGCTGTTTCAGTGGTTTGAGTGAATATGACATAGTCATATTCTGAGCCTAATGGTGAATCAACAGTTTGAGTTGGTAGTCCCAAAATCTTTTTGAGGCTACAGCATTCTGTGAATTATAAGGTGAAATAAAGACAGCTTTTCTCCAAGCAGGGTTACGTGTAAGGAATTCTCTTACCACCTATTTGTGGCCTGTTAATTGCAGATGAAACATCATGCGTGAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ ++#&&#%##$+%$&5>00)-13.30348.0+723-CGG?@7>8EB??A77;9;<*.$%%)56>E=GDCHEDCBB?40&?.ADD>D;8434)%%#%45+3(,?CE?HC;8--4)=9CCD?6GE7:>?@CCH@'-++',,323<=?=;@A>==0/?=ABA>730/2*;9:==??=GH>>@E>@B=><:<<=>():><;?FEIDGCD>?/0'/06;7C;=AA=EEDGIC-C.2A230*=>&<=3658>38GF11*.11162376*()3'.A89=<;<9@CD?@=;>;<;882EHJIE:23*)&&0>66EICD@*9,//22;;@7@>1,>,,+*'*24=>BG=E>20/&)%//ECF595:<@.>>>:<7.1+<89DDDCCD3?*7??::2<<:1%( +@SRR11410539.273682 273682/1 +CGATGTACTTCGTTCCAGTTACGTATTGCTAAGGTTAAACAGACGACCCCCTAAACAGGAATCGACAGCACCTGGTGTTGTTGGAGAAGGTTCGAAAGGTCTTAATGACAACCTTCTTGAAATACTCCAAAAGAAAGTCAACATCAATATTGTTGGTGACTTTAAACTTAATGAAGAGATCATATTATTTTGGCATCTTTCTCCACTTCACAAGTACTTTAGGAAACTGTGAAAAGAGTTTGGATTATAAAGCATTCAAACAAATTGTTGAATCCTGTGGTAATTTTAAAGTTACAAAAGGAAAAGCTAAAAAGGTGCCTGGAATATTGGTGAACAGAAATCAATACTGAGTCCCTCTTTATGCATTTGCATCAGGAGCTGCTCGTGTTGTACGATCATTTTCTCCCGCACTCTTGAAACTGCTCAAAATTCTGTGCGTGTTTTACAGAAAGGCCGCTAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAGCA ++ +%'%%%%&'-/-7>@%(%357.+'/(/2=B8<;+=GBAEC685970.-'''&)574)%+-*:84=CFFCAB=:B++>;IKDFFBGEAE851:C<;8<:;LK?-)=/2-8@537?;8,+)())-.1+1=>9@CD623&&''661((0''/,+0&,87;5;733*/49?@A?4-4%,$$$'+%$./+418::5.2*/6757(1./G@%3/>EDGGAB@669%)-;@B66:B7-4@?A?>JN?,.?>?A=?>:AK3,,'76=><>78/4AEGC==8:;>-&%31/-.9<==9710444857<=>>-,,:9>?A-.././.%$9;?@BE97A=69%(%(320)-&)/1<;.0-'+''===4/-=;ADBC6CDDCC<@B;;A>>?;?=C@IB?>;63,4;;=895$%249;>2==>94/*')$$# +@SRR11410539.2485496 2485496/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACACACCACTGGTTGTTACTCACAATTTTGACTTCACTTTTAGTTTTGGTCAAGGTACTCAATGGTCTTTGTTCTTTTTTGTATGAAAATGCCTTTTTACCTTTGCTATGGGTATTATTGCTATGTCTGCTTTTGCAATGATGTTTGTCAAACATAAGCATGCATTTCTCTGTTTGTTTTGTTACCTTCTCTTGCCACTGTAGCTTATTTTAATATGGTCTATATATACTAGTTGGGTGATGCGTATTATGACATGGTTGGATATGGTTGATACTAGTTTGTCTGGTTTTTAAGCTAAAAGACATGTTATGTATGCATCAGCTGTAGTGTTACTAATCCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGG ++ +$),.)-,9;;>6>1,%5>AD?;IECF;:;()/@HFEIA@BBH>@?>@<:?@3+,0.9;;AF=C:CDC@F:;B=G:7/*6:=FH>>?;;EA<@=>5=A?BC:OI>B=BHOH>ABDNC-1*1%%%&0*::?DFCDC;=<<,79B;HCLHFFA>;4&&@AG;;5678:<:@?>CDH@G@><.21AD@C6DD<>1,++;=H@=GHMJ5??7?FCDDA=>71*>?;@;.&#*=?8ABD+2/9;9=34-41:ACE7=?=:01GB:;@>EF9>GB??A;A@9:=?D=7A;:=IFME=*+@9=;<0)-)%$%$79=>B<;BCA=7BDICFG???EDEF9:ACE=?EEIDFIDE975)+5=.479:@>AEA?<;7B/1<;<33,)( +@SRR11410539.1341175 1341175/1 +CGGTAATACCGTTCAGTTACGTATTGCTAGGATAAACGGGCGACTACAAACGGAATCAGTTCAGCACCTAGTGCATTAACATTAGCCGCGTGACAGCTTGACAAAATGTTAAAAACACTATTAGCATAAGCAGTTGTGGCATCTCCTGATGAGTTCCACCTGGTTTTAACATATAGTGAACCGCCACATGACCATTCACTCAATGCTGACACACACTCATTAGCTAATCTATAGAAACGGTGTGACAAGCTACAACACGTTGTATGTTTGCGAGCAAGAACAAGTGAGGCCATAATTCAGCATATTGGGCATGGCTCTATCACATTAGGATAATCCCAACCGCAAGATGAGGTTTTCCATCACTCTAAACAGTTTTTAACATATTTGTGTAACCACCATAGAGAATTTGCTTGTTCCAATTACTGGTAAGCTCCTCTAGTGGCGGCTAGCTGAAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTAAGCAGCCTTATGCATCATA ++ +#$$($%&'(-1;5&'04511.--03&&('(*,)%*&-$($2:;?@>A8:59031.+)#&$$#'$&,,%/-2BAD==9./)&$&&'()(%%-.**'5221,'%%).+,,<>?C=6668,2:57<2:62:;0:96?>'+()-<22-*-97425);9;-0%0-5/2?@A9442,(&'&%121922%%%(()('))(,&-8((6:01)&#(%()%)2*=>;A;<;87?@B6/?2AC?AHG@;(0AC;7-11322/*)--7,?8BA31=88BBC11./15,.758601&'('..00-+(*'0%&%%&'))+)+0:27*/:3;0-24'449/,-083).6;9661$&'')&010-%##$'%+#&# +@SRR11410539.679840 679840/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAACGGAATCGACAACTACCTTGATAGAGACCTTTATGACAGTTACAGTTACAAGTCTTGAAATTCCACGTAGGAATGTGGCAACTTCTAAAGCTGAAAATGTAATACTGGGACTCTTTAAAGATTGTAGTAAGGTAATCACTGGGTTTACATCCTACACAGGCACCTACACCTCAGTGTTGACACTAAATTCAAAACTGAAGGTTTATGTGTTGACATACAACATACTAAGGACATGACCTATAGAGACTCATCTCTATGATGGGTTTTAAAATGAATTATCAAGTTAATGATTACCCTAACATGTTTATCACCGAAGAAGCTATAAGACATGTACGTGCATGGATTGGCTTCGATGTCGAGGGTGTCATGCTACTAGAGAAGCTGTTGGTACCAGGTGCTGTCGGTCCGTTTATGAATCGTGGGTTTAACATAGCAATACATCGCGCGTACTTCCAGTTTTCA ++ +%5358:2<@<573;A<@KHI==;776+)-&&-:=?ADI-D.FBCB?F=9-0-+668358>2123.,,89'5547:78))00:8=::;A.0-88589;:<<,,/1/20748B?<@DB>>==>89*6,(&&&+;4AA;==>7?<>=?9:<>CKDADDHCFB?7:3.B9:A7622)&$$%,74,523?:>A@BEF@EA?+$&,0--9;:=6347<>@?@;12487;9?BGD><35AFD@75C.(7)%-,111127??@<3.2:43798<;7?()('17B@2%$$*+76,+,/3340--/**4-14523-$#&&%%($*',,-$&#*(/50/% +@SRR11410539.2303602 2303602/1 +TAAGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACCGGAATCGACTAGCCACCTCCTTTATCAGAACCAGCACCAAAATGTATAACTCTCATATTATAGAATTTATTTAATGTTGTGTGTTTAAATATTGACACAGTTGAGTATATTTTGCGATAATTCATCATTATACCTTTAGGTAATGTTGCACTATCCTGTGCATTTTGAAGGTCACACTTTCTAATAGCATTCTTTGCATTTGTAAAGATTAGGCAACAACACCAGTTGCCTTGACTAGATTGTAATTTTGGGTAAATGTTTCTACATGGCATCTTTACACCAAAGCATAAATGAAATTTCTGTATAGTCAATAGTCACTTTGACAACCTTAGAAACTGAATCAAATCTTGGGATTTTATTATTTCAACAAAATCATCCGATAATAATCAATAACAGAACACACACTTAGATGAACCTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAATAATACGTAACT ++ +##%%&'&$/0(+1:=0*HJDE42.1.,888732:95$7%))258''$'&&'*2324364CBC<7@1=@:9C1/84@@ACB.,,-;89<@(/<,-,30*&,%%$%'&(&'.,-,4360:6);77704A=>>3($%$())50%$,,3>>?:HH62./-+&/4((&$%-./)*%*356546??AAD=?@B@?7A,,0($$$%-,17522857-/,,(%/02,+34.-.367878BGCEEACK4:@A/-60/.)%($$)000,,,'5.20'&$-0+(&&)''.34=A7>E@1*10'+646/9D?:.-%##$%&20*313265=EF235.)8;@AD:??8;438@BC477'',$$+(*(#)36BD=DBGGDGD7=F@?HE9<5:AE?@?;>?=GFAC7IGD1)7*:>78::6>?>552826''%..)+.,.,,%% +@SRR11410539.1971260 1971260/1 +CACTTTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGGAATCGACAGCACCTGTAGTTCTTTTCTTGTGCAGGGACATAAGTCACATGCAAAGACTACCATGAGGTGCTGACTGAGGAAAAGGACATAAGATATTAGCGCTTTCCACAAAAATCAACTCTTTTGATTGTCCAAGTACACACTCTGACATTTAGTAGCAGCAAGATTAGCAGAAGCTCTGATTTCTGCAGCTCTAATTAATTGTTGAGTCACATATGTCTGCAAACTTTGAGAGTCTGCCTGTGATCAACCTATCAATTTGCACTTCAGCCTCAACTTTGTCAAGACGTGAAAAGGATATCATTTAAAACACTTGAAATTGCACCAAAATTGGAGCTAAGTTGTTTAACAAGCGTGTTTAAAGCTTGTGCATTTTGGTTTGACCACATCTTGAAGTTTTCCAAGTGCCGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +)$"$%&567=63*,3-%%$-$..8@?BE+GE@8944596>;?=<><33)*$*#'0-)%18??@>:992&&$==9<>CB?JG/@8.+/FE?;+1.62/80<:55654''(&('9;?>@-1@>@@;<95553*(&,&$18?<8:;=A<1+1+$%%$*56B-0;6;<381,A22?AHD934:;;C<44>/0/=A/:<:A=B9DACFCCCE?;>&,31'*&+///592,)';9;;<767:@<<==9=<=0B9:BFFG82A8:9@8@B<13++*/../42,=>E0/56ACC9%%*/402==>@@=?@CEG88?@A=B@AEGE>=>-.))**A<>8864-$%143:65:3;964'''',<24LC%(234>4)+4854F94DEBCA;>?IHH?>8845/<4@B;=C><633450278<>850*)$& +@SRR11410539.714208 714208/1 +TATTTTTTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAATCGACAGCACCTTTCACAATTACTGTAGGCACGGCACTTGTGAAAGATCAGAAGCTGGTGTTTGTGTATCTACTAGTGGTAGATGGGTACTTAACAATGATTATTACAGATCACCAGGAGTTTTCTGTGGTGTAGATGCTTTGTAAATTTACTTACTAATATGTTTACACCACTAATTCAACCTATTGGTGCTTTGGACATATCAGCATCTATAGTAGCTGGTGGTATTGTAGCTATCGTAGTAACATGCCTGCCTACTATTTTGGGGTTTAGAAGAGCTTTTGGTGAATGCAGTCATGTAGTTGCCTTTATTACTTTACTATTCCTTATGTCATTCACTGTACTCTGTTTAACACCAGTTTACTCAATTCTTACCTGGTGTTTATTCTGTAGGTACTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +''.//-*)%%+/;:G5=5=EEH>?IIDD?=B783@KHCD>34471@C?CB?:;(2&)':>GAH>AAC:<=C0-./4/2B@BB=:>8B?H>DA7,,/*139:84>6>.-=@D>=8>AFEFF@BCC=?BD8D4DA>*+-?.2/*%':?5?010;48?>C@;7876>:AA57C9<<88>&'+-<@@2**-()+:=D..99::;<94/->=?;:E>@DDA;;7((.$(14DA@;,&),16697BA;/4ED@BHJE58@>)3&(-&:B71FFIJF;==LFJ:@HE:=?;CDBCCC*+::?:86:3*.?=C671@AAAEC7-.2)$%%103)+52368=;<12+6.26>;+&/232:+*-/6*=;92=AFB=@,6))264531##$$.*C<<<<>ACEA=ECA@9;B3B<>;@<=8??C>5135:+$*$$*5896A<<?3A/((0C=@<8@;83@:B?90?@>8.//./7+,,.559346966,('-6<==<<765;>D@A>@>?<>8ACFC?@E=9:389A<=E:6850:0.++$7<4;=:>E9BAFHD=@:;5665.59;6'*%'.++-7((3,85-:7()'<:<9<;=0>;?--=@ABBJKNKDC?;:7>CBB1>@>;C;????FG:?::925<>>@B?>6.$' +@SRR11410539.375351 375351/1 +ATCAAGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTAAACGGAATCGACAGCACCTACTAGCACTCTCCAAGGGTGTTCACTTTGTTTGCAACTTGCTGTTGTTGTTTGTAACAGTTTACTCACACCTTTTGCTCGTTGCTGCTGGCCTTAGGCCCTTTTCTCTATCTTTATGCTTTAGTCTACTTCTTGCAGAGTATAAACTTTGTAAGAATAATAATGAGGCTTTGGCTTTGCTGGAAATGCCGTTCAAAACCCATTACTTTATGATCTGCCAGCTATTTTCTTTGCTGGCATGCTAATTGTTGCGACTGTATACCTTACAATAGTGTAACTCTTCGATATGTTCACTTCAGGTGATGGCACAACAAGTCCTATTTCTGAACATGACTACCAGATTGGTGGTTATACTGAAAAATGAATCAGGAGTAAAAGACTGTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTCTAACCTTAGCAATACGTAAC ++ +$%'%&$&'('56885FA607=<483:337:=?55577<:?94./3832+&&'&$&)&/,,%#-.,69==90-*%%&56?=@(A;:)4@B>/1CC?BBC7DAG0:7/(=>@CF@CA+BE5AB?347;3/;2565.5?@';54,;D=$%%%)(+28<1;<6D>=?;:8>@C?>*.CD@AB>5<@DEF??D=>=97-,*,:E/>9:6)?AA777///0,$%&%0%$$,-;$:;ACGMH-(->7<85./.+,%$#'/)%*+%#%.//.49/-<=84-?D4591.*448;2==:7/6417*//)(%3.69939<99=6;680/45799>HC;,0(($'%'&%*-13-(445,568-1-4E@;83+5'$/5:>?GGPC;F<@/3&',&0'%+%%4500/5'/((')($'$$$%-,,89ACBCA,,96:5=D;:9<-706;::?A77127@DD.@*CBD<4875>BAEE>?NKBC@0@BGF<>;/.%%'''%%7;9>=8/;1320-,'5:5*'7<8<33+0%--7<36=8093151*33:<6//9=@BA>??GGCC8EDBHF??@$*:;F-@GC5543++-'../$'4>+,;7B6?710.-0:=>22**13667:;.+.22(+.6$*(+&.2;?==;5>C547;8;99::CEBE?A?5744&+?>CG@=7;:=?@>:1;78>BAD=87-*).12(+)+-(((21067117<<5.41')1&&&&;=GEF9'&&&(($%$$$#%&/=>A,*&$$'-')#(,,-34@?;'%4%+E)1:==D9AA0HI:-...8@/+>,*9:.(()%-.,/+,,-30.*&) +@SRR11410539.400038 400038/1 +CGTTGTACTTCGTTCGGTTACGTATTATTAAGGTTAAACGGGCGATACAAAACGGAATCGACCTTTTTGGCTGGTTCTAAATCACCCATTCAGTACGTCGATATGGTAATTATACAGTTTCCTGTTTACCTTTTACAATTAATTGCCAGAACGTTAGGTGATCTTGTAGTGCGTTGTTCGTTTCTGAAGACTTTTTAGAGTATCATGACGTTCGTGTTGTTTTAGATTTCATCTAAACGAACAAACTAAATGTCTGGACCCCAAAATCATGCACCCCGCGTACGTTTGGTGGACCCTCAGATTCAACTGGCAGTAACCCAGAATGGAGAACGCAGTGGGGCGCGATCAAAACAACGTCAGGTTTTACCCAATAATACTGCGTCTTGGTTCACCGCTCTCACTCAACATGGCAAGGAAGACCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGGCAAC ++ +'%#$(+*++,(056;%,130*'3,,*#&&()1>D>9<<=$)$6'&*136883.5788:955$'$$$$'8968;=B395;>;46.7898A@,2'2+/&&&%$)'$$&*()*0)''(%3=?@03*.5823;>>@@?B@FC=BDEC<84633-42433+2)-$%787+&&+/>6<9A=(;>=;G<96+;;:@:>DDJ?581->;86=5<*.C?@@;7@0<..8>@A=:83846215%%,6+,+2DEE=671349<,><<55232CAGFG;==>@A?>=-7.-7@A>.////2211<8755)&(13=<=B521A;?==D>@F<@@?>8850/1:8:8=OJA>;=98=92.,>>B78(650//-1(82:7182521,2$*/.25?;B@8>:;C:22227>>>B;AAAA89*-*-*++11.'$#$%$%& +@SRR11410539.934027 934027/1 +CAGTAATGCTTCGTTCGGTTACGTATTGCTAGGTTAAACCAGACATTACAAACGGAATCGACAGCACTCAGCCCCTATTAAACAGCCTGCACGTGTTTGAAAAACATTAGAACCTGTAGAATAAACACGCCAAGTAGGAGTAAGTTGATCTGCCTTGAATAGCAACGAGACTTCTGTGCAGTTAACACCCTGATAAAGAACAGCAACCTGGTTAGAAGTATTCCTGGTGTTGTAACTCTTCCTCAAAAGACAGCAGTGTGTAATCTCAAAGAATCGAATGTCTGTGGATTTTTGGACAGCATCAGTAATTGTAAATGTGTCTCTGCAAATTGTTGGAAGAAGGCTGGCTTTTTGTTAGACTCAGTAAGAACACCTGTGCCTGTGACCGTGAAGTTGAAATTGACACATTTGTTTAACAAATTAGTAGACTTTTGAGTCCCTAACAGTTGAGGTGCTGTCGAGATTCCGTTTGGCAATCTCTATTAACCTAACAACTCTATCTTTTT ++ ++%+(&(''7:>;CCDEF<1&0+)7;53>;A::EC45(1*++4445A5,*:=35A3<=94=1&#$%**).)*#&$$&%$,-''+'2)-,-&;4;89<=F?@>AABFJ9D9:???D=?8=+/,*0000$%-++%%14$$$$$)$%&$)($/1/&&$&%$$'&(%$'++,'('',-%&*')&%%-((&1149896&&%%%46875;D,)6-0-()(+$$$%$$%&&&(('%%&/)0178-/24./$&%%$%',0678CCE:9-0>67:AB<.9:D<<=8:/$%$*()%*-'&9<>??ED&39::=?;:96'%%$**724@BC>>==8<<<<<3%%2347&&)&''((-/'%&0((1.+++'&&;=:::>:/'%%&&(''+*).0###&%((())++0'()&,/.-- +@SRR11410539.1327526 1327526/1 +CAGTGTACTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACTAAACGGAATCGACAGCACCTATTGAGCAGGGTCGCCAATGTACGCGGTCGCCTTGCGCATCAATCTGGCATTGACAACACTCAAATCATAATTTGTGGCCATTGAAATTTCATCAAAGACAACTATATCTGCTGTCGTCTCAGGCAATGCATTTACAGTACAAAGACTAGCTACTGTTCTAATGTTGAATTCTTTGATTTATCAAACACTCTACGAGCACGTGCGGGTATAATTCTACTTTTTATTTATCTATGAGCAAATATTTTAATGCCTTCTCACATAGTGCATCAACGGCATGAGAGCAAGCTGTATACACTATGCGAGCAGAAGGAACGTAGAGAGCTAGGCCAATAACAAAATGACTCTTTCAGTACCAGGTGGTCCCTGGGTGTAGAATAAATTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATC ++ +)$))()(++-+1>8/*;AB*?=8225*60,+%+%%$268?=>A?=:/.))*5;>9&,'.;013;D7;>?==<1;1567>?4=/2@?BE:+)?FG40AB;;:<68@89>33@441/1164.001,-&&-/444*24-5/334.)9,+0%%**5485853<>67A;>1/2.)%)'%%%&30(>=???:<92,,.>>><<89@97'*+1,0'/'*@1*''(&&%%3680*9.%)&%$.13.**:8406;EA@?=04;<&0$$$*@8=<:?+,..5<57,,%27=8:?=?@:0,*)249@4165564++('.'%%$&()($$%'..36884994$%/455>79459<:92,.:B>35.2+7;=<>@FG=1=@9-0)+9.&.().:@A;:7@>?<16>GFC,=<<9;>99<<:8',-%(%($###$#( +@SRR11410539.2016084 2016084/1 +CGATGTAAACCGTTCAGTTACGTATTGCTAAAGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGTGTAATAATACTCAACTGTGTCAATATTTAAACACATTAGCATTAGCTGTACCCTATAATATGAGGAGTTCATACATTTTGGTGCTGGTTCTGATAAAGGAGTTGCACCAGGTACAGCTGTTTTAAGACAGTGGTTGCCTACGGGTACGCTGCTTGTCGATTCAGATCTTAATGACTTTGTCTCTGATGAATTCAACTTTGATTGGTGATTGTGCAACTGTACATACAGCTAATAAATGGGATCTCATTATTAGTGATATGTACGACCCTAAGACTAAAAATGTTACAAGAAAATGACTCAAAGAGGGTTTTTCGCATTTGTGAGTTTATACAACAAAAGCTAGCTCTTGGAGGTTCCGTGGCTATATGAAGGTGCTGTCGATTCCGTTTGTAGTCTGTTTAACCTTAGCAATACGTAAC ++ ++%$%#'#$##&2932+297/=?>BDE:/799$758(/0,3/9,>;?>::57643844666;26/4606%)#%%$)(&#%'%&1978<=7A@:A89??D>547<:*A3231/6:9=>@@B>?=;<>==9++,+.'&&%#&'*&%*),)++**25.24>+0;9C=;9@;@F>CDF??;9AB=8;;>F9?<;F@DCB<A>>6EF@?=B:)-=9:JJ?AC;./<=<=>A-))+3&:;=A@>?>8-2>;>B<:=@B=JA68:57==9<638:;=<6;:;5<=9FMKA?77:;C?B@)ALIL>>?@;/12')*CDDIFKA@>36:::CD=:)>=;BAA>9;653,;??9=???=?;>;C:9@86,;9;<6&'%%%''&''(..//.*)' +@SRR11410539.2156762 2156762/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAAGCACCTCATGGCTGCATCACGGTCAAATTCAGATTTAGCCACATTCAAAGACTTCTTCAACTTTTAAGAACAACTTCCAGAATCACCATTAGCAACAGCCTGCTCATAAACTTCTTGAGCAGTAGCAAAAGCATATGATGGAAGGGAACTAAACTCTGAGGCTATAGCTTGTAAGGTTGCCCTGTTGTCCAACATTTCTTCACAAAAACTTGTTTATGTCTAGCACCCTGCATGGAAAGCAAAACAGAAAGTAGTGAAACCATTTTCAAAGGCTTCAGGTAGTATCTTTTGCTTCAAGGAAATGTCATTGTGTAACTGGACACATTGAGCCACAATTTAGATGATGATTTCTCTGAGTTGTTGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACATAGCAACTCATCTT ++ +&$%/61:;<17K+.&1CD@@@FEBFABF340CIGGJG>=<>AA>=>9:243..0./35:?9%'+89;;G?CH>D>CCB?:?CF592=7(''*.38-9;52;;<5?@C98::$/58<<=?5?67@C@B;()?CB?35((*&+:+++.+)&((.2=AB)*4745556>:76311,-27206C@ACBA?A:@A@=@C9FA?AA?02@B5>>B=;776:4?FB=978'8:<=99>7;<>;%%4&'&227D=@7.,,-0**&1156/5-(/3:893466;906/4*&&44775.-/4/(+))-++,459:=>J>>IL2/C::7+%(&#%$'(,,0875*)*,0'(0(.-<<=8A8BEA?BDDF=E@A@;7<0/2./40/++9<8<@>>;7//<;9;9)-<74<;GNMCA@A6&?@>>D@:??AH>/7B><2335143<-4/*3(+)&*'&'%&'%&'+%)3;21<8=C><=D:;ADCCBJ@8((0;?AC6&%%(02389=5BC?01,>:=11,69;?CA:::6DEHH<6/&(''4:8:;;<==331,*-CAEF,;@ACA;FA3;7>?,&&4/;<77-<<78A.35+0.<98:8:,,+'/*)//,$'$&''$$&./1-7('+87745,*$(&%'$&5<>;;6865666@>?.1<>;00>;;,8-069=8BGAJ;?A?:?;>B>BBCC55+2+.8$(34=>E>80/%*$ +@SRR11410539.1317217 1317217/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAACCTTTCCACATACCGCAGACGGTACAGACTGTGTTTTTAAGTGTAAAACCCACAGGGTCATTAGCACAAGTTGTAGGTATTTGTACATACTTACCTTTTAAGTCACAAAATCCTTTAGGATTTGGATGATCTATGTGGCAACGGCAGTACAGACAACACGATGCACCACCAAAGGATTCTTGATCCATATTGGCTTCCGGTGTAACTGTTATTGCCTGACCAGTACCGGTGTGTGTACACAACATCTTAACACAATTAGTGATTGGTTGTCCCCACTAGCTAGATAATCTTTGTAAGCTTTAGCAGCATCTACAGCAAAAGCACAGAAAGATAATACAGTTGAATTGGCAGGCACTTCTGTTGCATTACCAGCTTGTAGACGTACTGTGGCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACATGTAACTTTC ++ +0++-.4/79:7@HG82BJH4>@<>=>:;B==&@CA;<.>>?B=A=+:;966'3(-)347<==6608>?G@@89663,236<@A:46E<>9B-47*@AA94A<9<+)%%$$&'(&+44:@::)12-@=@;>--0=:<@:?@9DE5.=<>31:97242+58;:@C*(77:<;>?:>BC?FGB>**2*+,*+3)8877;9AC@6;,+$&499@67E?;9438+0(0(9/06=?DFD@65;?ED@GG),;49<99?GA=@D1BEBA8;9999?59=>>01:@@D3++/@@@@GCBA05:312$-44&+4=885B@89B>AEKA9:>6A998:21=C?J@03@@933?<<:;@A;@:A;FD>?;@8067<8>EE0:@A8947A@@A>:A??DA=<588<++*)586:=<<6:@<=CAD2=''<=9)....19:5694' +@SRR11410539.724924 724924/1 +CAAATGTACTTCGTTCAGTTACATGCTAAGGTTAAACAGACGACTACTAAACGGAATCGACAGCACCTACCACTAGTAGATACACACAAACACCAGCTTCTGATCTTTCACAAGTGCCGTGCCTACAGTACTCAGAATCAAAGTTGTTACCACTCCTAACAGAACCTTCAAGGTAGGTGTTAGGAAATTGAATAATAGAGCCATCCATGAGCACATAACGTGTGTCCAGGGCGTAAACTTTCATAAGCAACAGAACCTTCTAGTACATTGGTATCATAACAATATGGTACTGGCTTACCAAGCATCTTTAAAAATTGTACATTCAGCAGCCAAAACACAAGCTGATGTTGCAAGTCAGTGTACTCTATAAGTTTTTGATGGTGTGTAACAGATGTTACCAACTGCACTAAAAACTCTAGGTAAGAAATGCAAAAAGTCACCATTAGTTGTGCAGGTGCTGTCGATTCCGTTTGTGATAAATCTGTTTAACACCAACAACTCT ++ +6)*%(+/-:;89;CB8399:/1%%%6;::-:@@HIB1,0-,&%(()*,.0012508;:;>=>BDA@<<@<<3/785:@<5655>?@D$(7+1,02/9:<>(@CC)AEIAHALBCHDD59::?A;=92363=@?<=<679&&&&6<>A<:AC?:B=8@((;63:=CE+D:;FNEJGA@IEG=?3%-;=3=G7?E;/@ABFA:BBDGEAEGFE@JF<6463.:94=@0??D94:.()*:>C8@DA@;4=.%>>?>BDC?B66FKE>3::<9;46:?@'9=?66=ED1//1;640?8CA@4.(+&%&&2.,+131((&&#(&%*%&%*'% +@SRR11410539.2158253 2158253/1 +CGTACTTCGTTCGGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAAACGGAATCGACACCTGTCCACACTCTCCTAGCACCATCATCATACACAGTTCTTGCTGTCATAAGGATTGGTAACACTACAGCTGATGCATACATAACACAGTCTTTTAGCTTAAAAACCAGACAAACTAGTATCAACCATATCCAACCATGTCATAATACGCATCCACCCAACTAGCAGGCATATAGACCATATTAAAATAAGCTACAGTGGCAGAGAGAATTAACAAAAAACAAACAGAGAAATGCATGCTATGTTTGACAAACATCATTGCAAAAGCAGACATAGCAATAATACCCATAGCAAAAGGTAAAAGGCATTTTCATACAAAAAAAAGAACAAAGACCATTGAGTACTCTGGACTAAAGCTAAAAGTGAAGTCAAAATTGTGAGTAACAACCAGTGGTGTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +(-.-89?65E7<%-55=;9;<014>:AA&4F??ADE?<;A89;5<<;786&).3./316)+96:>;<=?8?BDD;B%+2D-@FEA;596=>0/29+=><@@?EF88548;+,&'*3-099;=782*?ADAB>85467897,3016B;=<99CAH>@=CH@GJH@/98<77A??=A,-@'(850*,*(-,,-0110==))0.///4428=6253>A?CC<;;A=>@=?8::<;EA;=,ABF@=>>:4*/'.%((,++2;;9IJ<;A;8@B84<2-1(,2-3341*%'$$5379EDA830343>;;A@9:?@=;AAADFB2714299>.)7345))*=B>?ANIAC@B:CCBNN<2*&BD>CC70B>A<F;<:-1895$..780*,<@;>@::::>;DCI<:D@9:63?11?ACBB:,*.699CC>C=::7+$ +@SRR11410539.1888160 1888160/1 +CAGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACGGAGCGACTACAAACGGAATCGACAGCACCTAGGTGTGAGTAAAAAAACTGTTACAAACAACAACAGCAAGTTGCAACAAGGTGAACACCCTTGGAGAGTGCTAGTTGCCATCTCTTTTGAGGGTTATGATTTTGGAAGCGCTCTGAAAAGCAACAAGAAGTGCAGCGCCAACAATAAGCCATCCGAGGAATTTGAGGCTTGTATGGTATCGTTGCAGTAGCGCGAACAAAATCTGAAGAGTATTTAGCATCCTTGATTTCTGCCTTCCAAGTTACAGTTCCAATTGTGAAGATTCTCATAAACAAATCCATAAGTTCGTTTATGTGTAATGTAATTTGACTCCCTTTGAGCACTGGCTCAGAGTCGTCTTCATCAAATTTGCAGCAGGATCCACAAGAACAACAGCCCTTGAGGCAACTACAACAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +,%*205988744:<=AAC,933723$'+0/33;<>+++697:0;:(%--8-3@ECA>CEAFFK>969@@HB<==;+IPK<>EF>BDG@A9865//&9%&534'**=E;.3'1997)*:127*0-12<66<-,%&%%%*73+78566.)/&#%))')'&(3,&,;<8531,))'8:;9:A>=;B.'&$$#$%4*9>013/23338::$$$##0%*0*:'.<6:;??@CGDBC,531057308<@8;=?/=>>;01776--/799;HE9:79642(0//.#$#&>=@@B7=32795+6?;;2)-77/1-&'9>89>//05//$7)36;FC..-;(BFACE>98967<33.9=@47296:/)92:BF@@=2823:/3232:;;8+-$ +@SRR11410539.698621 698621/1 +CGATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTAAGGATCAGTGCCAAGCTCGTCGCCTAAGTCAAATGACTTTAGATCGGCGCCGTAACTATGGCCACCAGCTCCTTTATTACCGTTCTTACGAAGAAGAAGAACCTTGCGGTAAGCCACTGGTATTTCGCCCACATGAGGGACAAGGACACCAAGTGTCTCACCACTACGACCGTACTGAATGCCTTCGAGTTCTGCTACCAGCTCAACCATAACATGACCATGAGGTGCAGTTCGAGCATCGAACGTTTGATGAACACATAGGGCTGTTCAAGTTGAGGCAAAACGCCTTTTCAACTTCTACTAAGCCACAAGTGCCATCTTTAAGATGTTGACGTGCCTCTGATAAGACCTCCTCCACGGAGTCTCAAAACCACGTACGAGCACGTCGCGAACCTGTAAAACAGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAGCT ++ +-'%##&'45736@0?8AGGD749,-3HIGDF5/.,%5980-78BC4;((*-0/'/7<67?<=;<'&@>6-887B<58()'>>>:<>CDCD?A>:A<=C=?AALF739>CEJJBEDE;@A9:5<:D>@ABHF@@;44322%-)(''7;AC8FE+EFDC@A<63C4=>DE@<<55@?:2821,1-7=@7?:?4B:?-->?4;00.49@BID;::41=7578>@59.-/7(%,%$)?>LJC99;446421/,')*33?:8;/8@=BC@E6C:?:DK8?))*3668/-(+.,=A??==>0CB=B@C>=;D6%)*B@?==<>@;98<5=;7C9<79-.+5,666.(:;7?;=99@;@<@F:8=89;DBGDGHI??>>8::AAB>A=DBGGD=A>IEKC=D99<9;=CEHIDEF@CCC@;;;2,,<8/-+%$ +@SRR11410539.437199 437199/1 +CGATGTACTTCGTTCAGTTACGCGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACGACAGCACCTTGAGGTGGTTCTAAATCACCCATTCAGTACATCGATATCCCGGTAATTATACAGTTTCTGTTTACCTTTTACAATTAATTGCAGGAACTAAATTGGGTAGTCTTGTAGTGCGTTGTTCGTTCTGAAGACTTTTAGAGTATCACATGACGTTCGTGTTGTTTTAGATTTCATCTAAACGAACAAACTAAAATGTCTGATAATGGACCCCAAATCAGCGAAATGCACCCCGCATTACGTTTGGTGGACCCTCAGATTCAACTGGCAGTAACCAGAATGGAGAACGCAGTGGGGCGCGATCAAAACAACGTCGGCCCCAGGTTTACCCAATAATACTGCGTCTTGGTTCACCGCTCTCACTCAACATGGCAAGGAAGACCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +&%&%%%$449,?H72,1./$%$#$$%&*03>884B@>BEA::;==D@=;>=@C<6?>FCC@A<,3&&%4;><''57((:814<%&%)??CA=AIG1:7?CA?8>@=HE@9=686800.)$$(380-2(,+&,2+/-2779:HGB@AE@@>59<:>>@@@F79=CAFAA0139;?@...2395=457,-6D<>D@DCD6;?0065BCLNC*-::;4,+.'588?FDD::@C@B::9AAC@AD?@A@>BA@>F<9=8A=021,($4228A@@A1?77E@=?9.-(?EG;----@@@AF@@=5'* +@SRR11410539.1628695 1628695/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACGGACGACTACAAACGGAATCGACAGCACCTTCGCACAAATGTCTACTTAGCTGTCTTTGATAAAAATCTCTATGACAAACTTGTTTCCAAGCTTTTTGGAAATGAAGAGTGAAAAGCAAGTTGAACAAAGATCGCTGAGATTCTAAGGAAGTTAAGCCATTTATAACTGAAAGTAAACCTTCAGTTGAACCAGAGAAAACAAGATGATAAGAAAATCAAAGCTTGTGTTGGGAAAAGTTACAACAACTCTGGAAGAAACTAAGTTCCTCACAGAAAACTTGTTACTTTATATTGACATTAATGGCAATCTTCATCCAATTCTGCCACTCTTGTTAGTGACATTGACATCACTTTCTTAAAGAAAGATGCTCCATATATAGTGGGTGATGTTGTTCAAGAGGGTGTTTTAACTGCTGTGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTGCTGGCTAT ++ +#&-.7:;6717;B4<48:4ABD%(<>?DKKLGH88PSA??:>49:@?>C<=;982/@BA@<9<:*'705+.612-990>/BB)3<7CFC89*23>@@D>>8866678-)479+@@@4=?;?;22:$::98'.9GC9BBGDC@?;=>.:7?<2<>?61'68=?COFGI??C>@CDD=?A<923*)+@6>AB8=?5125,+>>@DDB?EFEB?9*01$%+,+177--3#&#,:=9551%(;DE>IH<>FDGFDCE>?H@7=NR=.DA>)?A3(05@@C@5A91/6''-9?CKEML>OEF==*(7@B<<8>F:11;@=<911*+4*<1;87G>7@AAJF:>:FDG4;<=;><<@>BAA;11/.%($%$$#&$# +@SRR11410539.1660895 1660895/1 +CAGTATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACAGTATTCTTTGCTATAGTAGTCGGCATAGATGCTTTAATTCTAGAATTTGTACTTCTAGTAAAAATTACACAATTTGTAGCAATAAAGTAAAGAAATAAGGCATATAATTAGGTACAAACTGGTTTTTAAACACCGTGTAACTATGTTAGTAGTTGTACTAACAACTGTTAAGAAAGGCTTAGCATAATTGCTTCTGCATGACATCCCAAGGGACACTATTAACAACGTCGCCATGAGTAGCAAGGGTTTTCAAACCTAATACTCTAGATAATTCGTGAGTTTCTTAATAGTAAGACTAGAATTGTCTACATAAGCAGCCATTAGATCTGTGTAGCCAACCTCTTCTGTAATTTTTAAACTATTATTTGCTGGTTTTTAAAGTATAATGTCTCCTACAACTTCGGTAGTAGGTGCTGTCGGTCCGTTTGTAGTCGTCTGTTTAACATAGCAATACGCT ++ +$#(%&%$.8;E>>>A=79AA;==BA@BEC=9:00%)GKDBAGEGBCC<3,.,,-9=.7D54@>@C>;>@;@BD@D==:?CC<+''->;0022174/'/$026;;:>;>@/;940)'9<<7%%19;,,&&*+88;<:2225**+-)/-,,.*&&/9:AA9:/7@FDEADEB@++9)))(*0/25D?86<9;69-.8>>EBE/),-,AF@<<8411>;@:F?@DAA1()*%*%(989>A?=@=<9;3:@;CBB>><8808,'1)%%'&&&+=?B?HBBFAC<@8888<@F6>9<73*=@F99D?AKHLD>8921=CF?A?A77;=?A?>:3%&>@BCB+->B:@?B?A45;%%.*98<76:7611/#%%&*5<;>:20/%(- +@SRR11410539.646790 646790/1 +GTTGTGGCTTCGTTCCGGTTACGTATTGCTAAGGTTAAACAGACGACCACAAACAGGAATCGACAGCACCTTGGTGAATACAGTCATGTAGTTGCCTTAATACCACTATTCCTTATGTCATTCACTGCTCTGTTTAACACCAGTTTACTCATTTCTTGCCTGGTGTTTATTCTGTTATTTACTTGTACTTGACATTTTATCTTACTAATGATGTTTTCTTTTTTAGCACATATTCAGTGGATGGTTATGTTCACACCTTTAGTACCTTTCTGGATAACAATTGCTTATATCATTTGTATTTTCCCTGAAGCATTTCTAATGGTTCTTTAGTAATTACCTAAAAGAGACGTGTAGTCTTTAATGGTGGAAACCGTAGTACTTTTAGAAGAAACTGCGCTGTGCACCTTTTTTGTTAAAAAATAAAGAAATAATATCTAAAGTTGCGTAGTGTCTGCTGAGTGCTGCTGTCGATTCCGTTTGTAGTCTGTTAGCATAGCAATACGTAAC ++ +%)+#$#%#$''300%(*321(50/2,-,35''*=:<8=940135836(''12','&'$/45@><7670,/8=,0;?FCC1614>@D@CAJHB<;=8,/A@7ACC>??2:4,CA?>>/4C>@B?;==?>>?AADCAA23/0452)*$$$71,::65-1%#$0+/7=888:>9CEB=D9A7>DGD%'3=63-,(0059;AA?;?=84.-5+0701%31-70///-,$$20),'&8;5@545)&$#$%%%++++*)+.78?9;<;97+'-.)%#%(6687=>2?3:;)9-++.*('&(++(%/0-,2%#&*'1>>?<%*+'-A97;869'&,'$&)&.;+5004620/**' +@SRR11410539.1567269 1567269/1 +CATTGTACTTCGTTCGGTTACATGTACTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCGGTAATAAAGGAGCTGGTGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTGGGCGACGACTTAGCACTGATCCTTATGAAGATTTTCAAGAAAACTGGAACACTAAACATAGCAATTGGTGTTACCCGTGAACTCATGCGTGAGCTTAACGGAGGGGGCATACACTCGCTATGTCGATAACAACTTCTGTGGCCCTGATGGCTACCCTCTTGAGTGCATTAAAGACCCAGCCTTCTAGCACGTGCTGGTAAGCTTCATGCACTTTGTCGAACAACTGGACTTTATTGACACTAAGAGGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCTTGGTACCTGGAACGTTCTGAAAAGAGCTATGAATTGCAGACACCTTAGGTGCTGTCGATTCGGGTAGTCGTCTGTTTAACCTTAGCAATACGTAACTA ++ +#$%%)(6;CD@AC7@*1;;&%'$$+%7=891BEDCF1@=??ACF=<:934+3/20662'+69/<=?@HD:@F?@7DE=0=4AGBEBA>62<72%&,,8+++((8=36737;>3358?=AB<$(<@?@:=***)($%&****..5.0C=44=4<>GL=A770=1?A?ABDG@B9ABKKD>@8822((%*37?CBC>EDC)1::>=?58@<:52'&&333'+337=4.1/36:66A33BA;;8D=?>?33@445..00(3(3*-0::6>AFEFIEBD=<;>;658-+35=ABDIL708&30))'&0922,.-,-0??AB79?>;0=ACAB6)&2;@BJ3.<..6<2388;<@..1;==4B?3*'18;1)1*8;473747:7:91*12EDDHHCEEB?@B8@>32271''''')%&((7:06*1C><43200*%$)36<4@/34:)2--?@=:=?;---.1''5223&)*$$&&).17916:4A?B>=>?>>=<24?A@B=42%("'$ +@SRR11410539.1895395 1895395/1 +TGATGTACTTCGTTCAGTACGTATTGCTAAGGGTTAACGAACGACTGGCTGGAATCGACAGCACCTTGAGGAGCCTTGAATACCAAAAGATCACATTGGCACCCGCAATCCTGCCTTTAATGCTGCAATCGTGCTACAACTTCCTCAAAGACAACATTGCCAAAGAGCTTCTACGCAGAGGAGCAGAGGCGGCAGTCAAGCCTCTTCGTTATCATCCGTAGTCGCAACAGTTCAAGAAATTCAACTCCAGGCAGCAGTGGGGGGAACTTCTCCTGCTAGAATGGCTAGCAATGGCAGTGATGCTGCTCTTGCTTTGCTGCGCTTGACAGTTAGATTCAACGAGGAGGCAAATGTCTGGTAAGGCCAACAACAACAAGGCCAAACTGTCACTAAGAAATCTGCTGTGAAGTGAAGCCTCGGCAAAGAATACGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACAGCCTCTTTTTTCA ++ +#($$$%%,0448=9,(&33;=6-+0-+&089;+&*6=;C>?BAGIDFHI=BAB=?B?7)($$$59780.8=6=::.7'&:25446<>4845./%):@==://1/01BB-(+GBFF)58A=?98.5/*/5:00881453,*&<8:;;>:<;/&%"&%''*%%($,229=1812<;=>;>$&()05;>A;>A@-;42%./2-*(0(+)**&)*''',1*3-/6530%+6;<=-));,+%)'&%%)./+&&68?F7F@7111=6-.'$&%&'+&'$%$%%%$"%(*))'$*%%*+1(+<96-/&'**,-,(68++<34C12>:::?;>=?'68=:>??=@A5=BB;:6)$%&%$$$,''656;;<<0+(1.+$&'&&+,*.6721B1)=9;GE18.78;.788;5079<148674(+('$$$(($$(%$##)(%&&%$$$% +@SRR11410539.1455590 1455590/1 +CAAGTGTACTTCGTTCCAGTTACGTATTGCTAAGGACAAACAGACGACTACAAACGAATCGACAGCACCTAGCCTCATAAAACTCAGGTTCCCCAATACCTTGAAGTATTTATCATTAGTAAGCATAACAGAATACATGTCTAACATGTGTCCTGTTAACTCATCATGCTTTCTTATGTATTGTAAGTACAAATGAAAGACATCAGCATACTCCTGATTAGGATGTTTAGTAAGTGGGTAAGCATCTATAGCTAAAGACACGAACCGTTCAATCATAAGTGTACCATCTGTTTTTACGATATCATCTACAAAACAGCCGGCCCTAGGATTCTTGATGGATCTGGGTAGGGAAGGTACATAATCATCTGCAGCAACATTAACATGTTTGAGAGCAAGAATTCATGAGGTCCTTTAGTAGGTCAGTCTCAGTCCAACTTATTTGCTGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +&%'#)*679;=@=A>%*8;;A=<798444:6+,'5&%+1%;9:;7<8;73956+*&)+009:>?82;8',<*;:>>44@BAG@+38/>;6)000DFD>586864.+*&,..-8969:71444,4+*),7?A4=?99B?>8@;;:>=8=?D0/%%(*00))$#$%D<><8;=922462)*,1/:79:99+;4088.*/%,.042/2+.6;=H9<6ACF@78,&*(14&@02106?:42:@+567<845575C@>=:==AB>?@=B8+?AAC64605579>7<0:05453?KHFB28:=;?A955)1%89,-0*3,/8;56:8)'/'%+-%'$$+&%*%%&'..:<2++),%512%*(167+)'%2789?<@EC?+?*D;@5879:==:44;+,)**88,/,02,0114>943%&&& +@SRR11410539.2193881 2193881/1 +GTTGTACTTTAGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAGATCGACAGCACCTACTACAGTCAGCTTATGTGTCAGCCTATACTGTTCGTCAGGCATTAGTGTCTGATGTTGAGTATACGGAAATGCAGTTAAATGTTTGATGCTTACGTTAATACGTTTTCATCAACTTTAACGACCTGTGGAAAAACTCAAAACACTAGTTGCAACTGCAGAAGTGAACTTGCAAAGAATGTGTCCTTAGACAATGTCTTATCACATTTAACATCGGCAAGGGTTTGTTATTCAGATGTAGAAACTAAAGATGTTGTTGAATGTCTTAAATTGTCACATCAATCTGACATAGAAGTTACTGGCGATAGTTGTAATAACTATATGCTCACCTATAACAAAAGTTGAAAACATGACACCCCGTGACCTTGGTGCGCTTGCATTAGGTGCTGTCGATTCCGTTTGTGATCGTCTGATTTGTGCCGGGATTACGTAACTTA ++ +%%&,((%%&(():;@<DGC>2.4+;;<@D<8CBC?=8535?:6?=BCA?@@A>?,0,12'=<;B@@@DC?5'&00238733;?@FD>@DHBEC:/8&51'$$3'(+())),*,/5)*/.089792.'-24@@;@>--5:A?BCL:CC?C229999::5,++++*-'(1312+63;<=;=79:95>:?:D67>?5(.$$$)+*)'#'04:45+4268:E@00714<>C=CD?1)+%%&$&'%%$&*/.6:2217>>C=257)5:9:9;;0DEBDGD==BD2AECABC3EB=:@<><=720444=>9B1@=:A;0)<0IDA722.4/B;?=8:67<;C?@@C@('&'$%%2:98:8=?@/+,-5+4017CB=87@ADEJH:95;>;89GJCB?HEB2822((1*/'&,,#$+,1/47C<=A@>BA@=@;>?D=A8*'$&')&:/52757,$###(*)%+29>8765%%,% +@SRR11410539.2322211 2322211/1 +GTTGTACTTCGTTCAGTTACGTATTGTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTAGCGGCCTTCTGTAAAACACGCACAGAATTTTAAGAACAGTTTCAAGTGCGGGAGAAAATTGATCAACAACACGAAGCGACTCTGATGCAAATGCATGAGGACTCAGTATTGATTTCTGTTCTCAGTATTCAGGCACCTTTTTTAGCTTTTCCTTTTTGTAACTTTAAAATTACCACAGAGTTCATTGTTTGTTTGAATGCTTTACCAATCAAACCTTTCACAGTTTCCACAAAAGCACTTGTAAGGAAGCAGAAAAAAGATGCCAAAAATAATGGCGATCTCTTCATTAAGTTTAAAGTCACCAACAATATTGATGTTGACTTTCTCTTTTGGGTATTTCAAGAAGGTTGTCATTAAGACCTTGAACCTTCTCCAACAACACCAGCAATACGTAAC ++ +(+,+,(%%*@@G1-&85686.?89:(&&'4=EE=?58:7932/,*(-/238365?=ABHCFAAG@?F>C4C*29>:;8,-/?BGFC><9;6798/&&)%%#&%(%,$'2B4A2.&;164<,:)539..3-,+,#$$(()63,+%*.''08??@>D?EFGH211-(#%'+%%*)($(&,,+&'+1.)&*+$$&,(47<,9:;BAE??DDHD;4-5<===G<=CAFDE>;3.)=@>HN;3254567206$(%+&&#%)&)A7@BA22;822794/$$((%58;@4814<7987>AA@1408:;3.$.(&&&%+##'$-)-))(+*@53)&3$$%)7965A=7CD1271<=@246<@BGH==8=?801$>?BFAA755DA:;81?A>AFD?>F@G>>5,)43:?C/?$%/2,4>;/,25;>@3332&%$$*#078787:,970+;<2@@:F0@DEE?CC>+/& +@SRR11410539.881123 881123/1 +CAGTAACCTTCGTTCCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCGGAATCGACAGCACCTAGCAGCATCTACAACAAGCACGAAAGATAATACAGTTGAATTGGCGAGCACTTCTGTTGCATTACCAGCTTGTAGACGTACTGTGGCAGCTAAACTACCAAGTACCATACCTCTTTAGGTTGTTTTAAATCCTTTAAATAAAATATCATCTTACTTTAGGACCTTTAGGTGTGTCTGTAACAAACCTACAAGGTGGTTCCAGTTCTGTATAGATAGTACCAGTTCCATCCTCTTAGGGAAGTCTAGCCCATTTCAATCCTGTAAATCGGATAACAGTGCAAGTACAAACCTACCTCCCTTTGTTGTGTTGTAGTAAGCCCCAACGCATTGTCATCAGTGCAAACCAGGTTTGTGTAGTACCGGCAGCACAAGACATCTGTCGTAAGGTGCTGTCGATTCCGTTTATGTCGTCTGTTTAGCCTTAACTACGTAT ++ +(&%+#$#$#%(3?<*11799..'+,,1088$%.A@;;>;7..4(1&79-,*-&/369:9;>EBBAC@?93-05134;;B.%4++/**&,)-&&:'-EHCDGE@;CCI=>G31461-)26<=55+-*)%+7;<;;:56?34.=5BB:10&+.568117;@B=B9969:<;=?@F776&$++*&'&%%*%%#$$#'+95><=7223-.3*+6-8'):38?B@8GHEC@=:=786<:@=1<9/*:9@4B28+.*67?>=;027''0+;>7,3//%)$16*+',5.+)*.-37''*-,628?9C=AAC=?746C=A%&)==5576;;0*:8;5;$$&<(EA<787.+$%$*'(01%%$$%(.85:===@)&?7A@<444.'+&++'(B:A;:316567;<.(;=3079@E=76D4>>9=<&&.;D@DEC>@>;8=;=>FD+#%%05=>G>@88,'%$&$&%&&&$+$%#% +@SRR11410539.2128799 2128799/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCTCCTTTATCAGAACCAGCACCAAAATGTACTTAACTCTCATAAACAGGGTACAGCTAATGTTAATGTGTTTAAATATTGACACAGTTGAGTATATTTTGCGACGTCATCATTATGCCTTTAGGTAATGTTGCACTATCACCACATTTGAAGGTCACACTTTCTAATAGCATTCTTTGCATTTTGTAAAGATTAGGCATAGCAACACCCGGTTGCCACGCTTGACTAGATTGTAATTTTGGGTAAAATGTTTCTACATGGCCATCTTTACACCAAAGCATAAATGAAATTTCTGTATAGTCAATAGTCACTTTGACAACCTTAGAAACTACAGATAAATCTTGGGATTTTATTATTTCAACAAAATCATCAAACAATAAATCAATAACAGAACACACACACTTAGATGAACCTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACAATAATAAC ++ +$%%&-2/;B;=>F270:FD@<9CB>D@@>-.?@HCBD11()/6999:4.::31&)%+-65:24/74179).:==EC*&;>7?DD?N:GIFAGFIK?@:;''(;=66&(+&(+,*(/%%%+&-111657>AA>35/0@<;<@8;;9DBA26,6ACEG=8-2;AGEC>CD::32.(03767232-0077890*10-:<56@B@BG@B72920/$''$'+--9-9399:>8886?49@1B=BDGDAGJI@CA@BPH>;47867600*6=B<:9998>ABCA.5?FEBF4A56;::;5255-1:77===AIGEBJ==E@E:<89>?8:C=?DB16=20AHIJB<:::=2*B6DF?C5.;=33BCDA=B@7:8=FCE??=@B>>;FA>CH>??;8;<:FHHHACB@GDEB,-7==A@;>1+>.0'+058<=?;A<<;><9<760.9$4&/47565:39977<<<;>>)'&&&$$%$&*' +@SRR11410539.2374698 2374698/1 +GTTAATACTTCGTTCAGTTGCATATTGCTAAGGTTAAACGGAGCATTGCAAACGGAATCGACAGCTTCCTTGGTGAATACAGTCATGTAGTTGCCTTTAATACTTTACTATTCCTTATGTCATTCACTGTACTCTGTTTAACACCAGTTTACTCATTCTTACCTGGTGTTTATTCTGATATTTACTTGTACTTGACATTTTATCTTACTAATGATGTTTTTTAGCACATATTCAGTGGATGGTTATGTTCACACCTTTAGTACCTTTCTGGATAACAGTGCTTATATCATTGTATTTCCACAAAGCATTTCTATTGGTTCTTTAGTAATTACCTAAAGAGACGTGTAGTCTTTAATGGTGTTTCCTTTAGTACTTTTGAAGAAGCTGCGCTGTGCACCTTTTGTTAAATAAAGAAATGTATCTAAAGTTGCGTAGTGATGTGCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTATTAGCAACGTAAC ++ +&$%#$'&23538H?92:68&%#)))+-3;79,H@;BD;=%+%%9+,/'*/0-+69=<559-+.&#$$$$$(%+3;AA:?DFDF:=;??=>9>>9<@D=>=;94<=C>BCB9950.,'4')?@BC:;>=76FD@@1,4?>A>1(232)*'/+,1869>?=8:01554?CC@KFF?AEDG=DAC;;=86>166553/045>EHD@?46@?@FD?ALG@@B@9D77@8:EF@@:D>>@@AC@<;=A>))*$&5%%%%)5.)$$6=CC??DK70;EGIJKEF=728$22:A73=6288=@JJECDA34@@@AK;=BDE>>@;;=BA913B/A967=:BDAA82;??=ACALK>GIDGF@CH<&9C@8:8,&>)@A0,4@@==8<@ADBJDDB>@>?>566F0>38B?-%%#'%$"#$-68HA?CGKA?B>O<>8@A:<..6D?..-+''67?<8=>=<48>;>3+,$*&&(4<>*)>;>'(=@6126&(6AA?=:*+;5;12%1'1'*=<:@@D;@:?22?<8=@=-1F??FN<0DAAGG9GAB;?84-68989B4C2.7;@<6@>=8=9DB@0/-()(B?DCGH=?G>BB?><>):&97??E@C@G;566$#)&)>?<8E@??=@CBBCCBCABA9<:GH>6>67:;9<;BD=0-&*16:?ACC@:>AAI@?B>B>C66880.';,782-(.%34350./..+$$%%%*$$ +@SRR11410539.1106375 1106375/1 +CGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACCGTCGACAGCACCTAGCCTCATAAAACTCAGGTTCCCCCAGCTACACTTAGTGTTATCATTAGTAAGCAACAGAATACTATGTCCTAACATGTGTCCTGTTAACTCATCATGTAGCTTTTCTTATGTATTGTAAGTACAAATGAAAGACATCAGCATACTCCTGATTAGGATGTTTAGTAAGTGGGTAAGCATCTATAGCTAAAGACACAACCGTTCAATCATAAGTGTACCATCTGTTTTACATCTACAATAACCGGCCCTAAGTTCTTGATGGATCTGGGTAGGAAGGTATAATCACCCTGTTTAACTAGCAGTATGTTGAGAGCAAATTCATGAGGTCCTTTAGTAAGGTCAGTCTCAGTCCAACATTTTGCTAGGTGCTGTCCGATTCCGTTGTAGTCGTCTGTTTAACCTTATGTACGTA ++ +*%.-.+---.4677228=<==?C=@?>D995>JDCF:00/27;?><@91/%$&%+*05/((99?=;A:CC<<,48<82;63.4;268743'1%%'%%%%&(++8:BC?;>897.2+%%)),-7<6->;8&&4.0%%(:<>B7=<><,,0<>A@31.6460/(*$$-%***<>8B@97761132&.1+3/19:58;:34*<841A>ABA>,,=*,8956273;7A?CB=5=97;;D<:B=89.:?;D@>918<5*+(+%3.1+2585ID;>4-6(*&)+=<>BCD@AEFBB?=6%&015-'''&$%%12;<=,,*+,1,=><=<89054*+7;;>34.6*-%63@B<:47567359>:8333/3(*$')-29;38-.-1$))&*0.*(+'*3))3);82?<+,.:2=;@67-947))@@@@BDFLG@A?=8.@9748$$93.*.676A>:;55A?89=21-/./&$$$$)$%% +@SRR11410539.2020881 2020881/1 +CAGTATGCTTCGTTCAGTTACGCATTATTATTGCTAAGGGTTAAACAGACATTGGCTTCTAAAAACAGAATCGGCGGCACTAACCTTTCATACCCAGACGGTACGACTGTGTTTTTAAGTGTAAAACCCACAGGGTCATTAGCACAAGTTGTGAGTATTTGTACATACTTACCTTTAAGTCACAAAATCCTTTTAGGATTTGGATGATCCTATGTGGCAACGGCAGTACAGACAGCTTACGATGCACCTGAAGGATTTGTGATCCATATTGGCTTCAGTGTAACTGTTATTGCCTGACCAGTAAGTGTGTGTACACAACATCTTAACACAATTAGTGATTGGTTGTCCCCACTAGCTAGATAATCTTTGCTTGGCTTTAGCAGCATCTACAGCAAAGCACACCATGAAAGATAATGGGTTTGAATTGGCGACATTCTGTTGCACATTACCAGCTTGTAGACGTGCTGGCGGCAAGGTGCTGTCGATTCGTTTGTGAAGTCATCTGTTTAAACATATAGCAATACGTAACT ++ +&%'7;99788;:KF51930(()4((,&.0,,0((+&'%'0++/250(*,3%$%''$&+$'56351,('$-')#$'$'(((,.0&+&*-(//(+5423A@242//&*6;87766432462E?@=CIF<@DFB>$$(;?855..-44>9?;5<@6643+&)$#$$$'0.)#$&-.,,0(%4-$&*%69833>@GH:@6>77+-&02+1<<9A;<8..49;:;92%.),/*,.@94>=<8@@@=44=C==;7/20>7786899@C?@E;?>E@344=:B:=G:B6>7<><>;;A<4%#$%$&%%%&&'')+0<==884>+988-))()'#$$%%%('%/)'')$&'#'1.-,&'$%&*&+,/5<44@?3$$-))-11354''-2:;;:/,2)++'.3-17/10;>@BD;63%(&,1075+&%'$$*.3%*+''26/+,''$(%*58=00//9<;98)) +@SRR11410539.1500677 1500677/1 +CATTATGCTTCGTTCAGTTACGTATTGCTAAGGTTCAAACAGACGACTACAAACGGAATCGAGCAGCACCTATTCTACACTCCAGGGACCACCTGGTACTGATAAGTCATTTTGCTATTGGCCTAGCTCTCTACTACCCTTCTGCTCGCATAGTGTATACAGCTTGCTCTCATGCCGCTGTTGATGCACTATGTGAAGACATTAAAATATTTGCCTATAGATAAATGTAGTAGAATTATACATAAGGCGTGCTCGTGTAGAGTGTTTTGATAAATTCAAAGTGAATTCAACATTAGAACAGTATGTCTTTTGTACTGTAAATGCATTGCCTGAGACGACAGCGAATATAGTTGTCTTTGATGAAATTTCAATGGCCACAAATTATGATTTGAGGTGTTGTCAATGCCAGATTACGTGCTAAGCACTATGTGCATTAGCGACCCTGCTCAATTACAGGTGCACAATAGATTAGTTTGTAGTCGTCTGTTTAACGTAGCAATACGTAAC ++ +$#&'%%$()))1;:1,=9<.?>?<=B0/A<='646$$&#+)*/,46'%128?LF591*),+*./0,9@?1A@?9@?=BBCEA:A/487((<;><;>DC?@959EHGBBB::6.449:89>7<@@;@7<:<=B=>56*)0'...3;=?.%%?;C;A@JH@C?FCFIJAAA;+$9$98:<0+))*)%&&*.,=11228F:86<7=447:I@>B>DD?D7<=>304?1>DBC:;@FFC?@99@<<53,.*&%%$$$$+7?@=>@=2+*+&&(4@B2?>=2236-55998;AEDD?BJ:6-(6BBLM83>CF@?7;)'26473:5:99-;.-*---)*&$+(#*,///8467.7:@@BAA<2/.%$2)045>BB@<,+' +@SRR11410539.54220 54220/1 +AGCTTTTGCTTTTGATTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCAACTTACTCCTACTTGGCGTGTTGTTCTACAGGTTCTAATGTTTTCAAACACGTGCAGGCTGTTTAATAGGGGCTGAACATGTCAGCAACTCATATGAGTGTGACATACCCATTAGTGCAGGTATATGCGCTAGTTATCAGACTCAGACTAAATTCTCCTCGGCGGGCGTAGTGTAGCTAGATCAATCCATCATTGCCCTGCACTTCATAAATGCACTTGGTGCAGAAAATTCAGTTGCTTACTCTAATAACTCTGTGCCGCACACAAATTTTTACTATTAGTGTTACCACAGAAATTCTACCAGTGTCTATGACCAGACATCAGTAGATTGTACAATGTACATTTGTGGTGATTCCGGCTGAATAAGCAATCTTTTGTTGCAATATGGCAGTTTTTGTACACAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACTT ++ +&&'('%&#(,,,+)((+/*38;5B>D?GF8>@>?,@DDBFG7>6:6@A>B;@??2+/2369=9E=F?/@;<=??'&B:=81<=A9=9443&'$35;>>@;BGMB@BDE@DBBJ35ABB5.1+D>??BGEICEC=BC5<2@HDA@44::<543+0$'007;?@B>/4)0=7CEF?=77KIF?B2%*6-../==;9;:==CB307=26+$$7-4447:8;9;>;=<0/%('&&)%))&'&$"&$$&'/01-482>=>@=6945@?'&=B89/C.61*..5966%>,21###%%'%*-57876//20/./(A9CBA>>0)1)65;BAEHBJF>ADC@B?EI@@D-8.A=-+252789115=?>@??<06;BABBA,/36>45==$.%'*)*$%)()).>B55GEGHB78:66:;<;1-*%)*9>>A>ICB>C@A'ACDA?@=CCEKB'468;>6>44640;?>?>@;5700.,)))9;;=:;910%%' +@SRR11410539.1110144 1110144/1 +ATCATTATTACTTCGTTCGTACGTATTGCTAAGGTTAAGCAGACGACTAATATCGACAACTTTTAGCCTCATAAACTCGGGTTCCCAACTACCTTGAAGTGTTATCATTAGTAAGCATAACAGAATACATACATGTGTCCTGTTAACTCATCGCGCTTTCTTATGTGTGTAGTACAAATGAAAGACATCGGCATACTCCCTGATTGGGATGTTTGTGAGTGGGTAGCATCTATAGCTAAAAGACGACCGTTCAATCATAAAGTGTACCATCTGCTGATATCATCCACCAAACAACCTGCGGCCCTAAGTTGATGGATCTGGTACACATAATCATCACCCCTGTTTAACAGCATTATTGTGTTGAGCAAATCATGAGGTCCTTTAGTAAGGTCAGTCTCAGTCCAACGCTTAGGTGGCGATTCCGTTTGTAGTCGTCTGGGTAACATAGCAACCAAC ++ +$#%$"#%#%'&+335:,()2,-)%%$%(+178+EB@9;%/,.-1+)&&$$'(1-908++10001636750/39<<78=(,??<384//%+/1204833GA>972%1)++(''(.02;9(;%&7882:(-4.+))52770/,,,'*84**%$$$&'$30%%%-(),(%'.53635470($)&+('%*-232,.67'%((&#%&&'34:691'$%,+-/-.801++$./3-3*+'&$$'#%/044''.%(7;=7;9881&&/&%+1,*(,02*(3+<;?<3055-'&%/-0473$-1'-($(+%)&&&$#'&&)$+3--5++4107//4802,668+<79**2+)(&$$%*&+0&'&-./2898:9.,0-28<72<5&&$$%*-'46/4$%&&&'$ +@SRR11410539.823019 823019/1 +ATGTTGTACTTCGTTCAGTGCATGTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGTTGACACTGACTTAACAAGCCTTACATTAAGTGGGATTTGTTAAAAATATGACTTCACGAAGAGTTCAACTTCTTTGACCATTATTTTTAAATATTCGGATCGAACATACCACCCAAATTATGCCAACTGTTTGGTTGACAGATATTCTGCATTGTGCAAACTTTAATGTTTTATTCTCTACAGTGTGTTCCCACTTACAAGTTTTGGACCACTAGTGAAAAATATTTGTTGATGGTCATTCCATTTAGTTTCAGCTGGATACCACTTCAGAGCTAGGTGTTGTACATAATCAGGATGTAAACTACATAGCTCTAGACTTAATTTTAAAGATTACTTGTGTATGCTGCTGACCCTGCCTCTTTGCACTTCGTCAATCTGAGTTTATGGATTTATCACAATAATGAGTCGTCTGTTTAACCTTAGCAATACATGCT ++ +(0112:6**1-23<2)#%1%0(''.+*'&'>DDFG77((1)>>?@6523+3.0-;;9:42.-13:;AF514<5/678042(+%$2351,$%%$,*($#'0'&#(.**0(,)&'$%(*,-++++,)&'&)$)-/,+%#$&&&&'(+,--/0+))$%$##**-,7:;5./%()'&'',&+'(%',;:>?0'95;AB<=>139=7>@?>=EB<@62<1-:A>44DD?<6:>;9%&($(1.*,/47/)00>0)+%/1+-,%#(*0068()$()'+*:5<:;;+*196324,2/7>=9:@<=.,%#'.-)6?;6145:;<8244765?@.40.-)(((*%,*+*,::3/59;BD=7.((&%$$#%&$#$&$&&%**+.%$$,$&%&)),&*+)$()%&$$$$&*$$08:.(-,6::<67@BAB<9;<<9:3$$$"# +@SRR11410539.1027762 1027762/1 +GATATTACTTCGATTTCAGTTACGTATTGCAGGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCATCTGGAGATGCCACAACTGCTTATGCTGGCCAGTGTTTTTAACATTTGTCCAAGCTGTCACGGCCAATGTTAATGCACTTTATCTACTGATGGTAACAAAATTGCCGATAAGTATGTCCGCAATTTACAACACAGACTTGCGGTGTCTCTATAAAATAGATGTTGACACAGACTTTTGTGAATGAGTTTCGCATATTTGCGTAAACATTTCTCGTGATGATACTATCTGACGATGCTGTTGTGTGTTTTAAATAGCACTTATGCATCTCAAGGTCTAGTGGCTAGCATAAAGAACTTTAAGTCAGGTTCTTTATTATCAAAACAATGTTTTTATGTCTGAAGCAAAATGTTGGACTGAGACTGACCTTACTAAAGGACCTCATGAATTTTGCTCTCAACGGAATGCTGTCGATTCCGTTGTAGTCGTCTGGGCGCAGCAGCCAACGTATCAA ++ +&#&&&*&,,.&'$8==><<@FH@B>C4<.,-/199(&.&(.9770&/1-477786++/.*(%)#%$%%&--3?HE@A?<99:?<&&;???AC>8/-,*+62AA=>,,)(,00384;78//<=<+166:62:+)','446.2-/9<88+6(&&*++%%'&//,,1>:@6==:80C;66(;B95:22A?@,*15=>=FB@61089:187::/4*('4451--+&$$#(+%+(../832?3@C18237778'-.*'(*+&'(,46988686>22.=?D685GAEAC??F76FKB:6@ANKA--,1,&*6/0=HHDCED>:=797&0('$&.;EC99<>;<@E<=+7;<2A89<>ADE?CFBB?<:C=@AIB9C@HJ.&75%+(())//1HJSMABK@7C::=*-***+595:?BDJC5:;FD5/8504::;5,,)$&&$%%$%#$#$'(%%+-$% +@SRR11410539.1372458 1372458/1 +CAGTATTGCTTCGTTAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTAGGTCTTCCTGCCATGTTGAGTGAGAGCGGTGAACCAAGACGCAGTATTATTGGGTAAACCTTGGGGCCGACGTTGTTTTTGATCGCGCCCCACTGCGTTCTCCCATTCTGGTTACTGCCAGTTGAATCTGAGGGTCCACCAAACGTAATGCGGGGTGCATTTTCGCTGATTTTGGGGTCCATTATCCAGACATTTTAGTTTGTTCGTTTAGATGAAATCTAAAAACAACACGAACGTCATGATATATAAAAAGTCTTCATAGAACGAACAACGCACTACAAGACTACCAATTTAGGTTCCTGGCAATTAATTGTAAAAGGTAAACGGAAACTGTATAATTACCGATATCGATGTACTGAATGGGTGATTTAGAACCAGCCTCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +)$,()#$'036@:B=496:H=:1FEG><<'(1EHFJL><457??:@;'(.3:=ECHC7*)8:44):;=8>BAA=/<5798253/35./.**/)-<@@B63702-.F@DCBD8@DD:59;96B=:E6,1-***798)56:<;<:>?5=@GFADC@BCF?EDCGA>;6:78:>A44>;?BA?G?CABCJI>>9>ADELB:;7CF?77934717//5538:76324%$$+23755:<=GCC63821-4)*/7++,./:;<*)>?5=@;0/1GECJGDBB>>79GE>:>>?ABBADC?BF5,(30=?9:$'322;>C<B84249DBFA38G>GDFF6=-/8=4:-@@9:))7,C@A>?AB@<8=A@?;7@=>87%% +@SRR11410539.1731916 1731916/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTAAACAGACGACTACAAACGGAATCGACAGCACCTACACACCACTGGTTGTTACTCACAATTTTGACTTCACTTTTGGTTTTAGTCCAGAGTACTCAATGGTCTTTGTTCTTTTTTGTATGAAAATGCCTTTTTACCTTTGCTATAGGTATTATTGCTATGTCTGCTTTGCAATGATGTTTGTCAAACATAAGCATGCATTTCTCTGTTGTTTTTGTTACCTTCTCTTGCCACTGTAGCTTATTTTAATATGGTCTATATGCCTGCTAGTTGGGTGATGCGTATTATGACATGGTTGGATATGGTTGATACTGGTTTATCTAGTTCGCTAAAAGACGTAATTATGTATGCATCAACTGTGTGTTACCATCACTGCGGCAGCAAGACAATATAATATTAATTACTAGAGTGTGGACAGGTGCGCAATCGAGTTCGTTTGTAGTCGTCTGTTTAACCTTAGCAATGCGTGAAAAGAAAGCT ++ +&*,7<:=?;;6D3;5?FC?AB@FDF54;-,-).=@F?DAD?EI=BC>AC<3,0.986486<1?>EEE@BA6@@A=:9/1+2CVGD@88888&+?@A<:;//6@-/87;A9A?=AB=FBFCBIGMF?98;GEDADKC408::425//3;<@<;;8;))%&(=5>22,/(9778D709341.6968+68;:B@=>A;90*-%-7>=CBC<=;6=<;=AE>EA=@??18<55=>???ECK<..846),;?AD7A<54.((/1/74769?HHGDAB@63*+;AFB@9A?=854%,?2.$,+/3+2>@*)29+'+,/()69EJ2%(54'*(*)-/(++.%$4/6;$$++%,'%%+-($(*%-##''-$%.,$4,-'%%#$%')$'#%#%&++,%$&$'',...26=7-4:2%#$$**(&%#'4);5D@J66B:5/);?9<45B989789201//$$,'+&%$$##''')$$ +@SRR11410539.1635244 1635244/1 +GCATTGTACTTCGTTCGGTTACGTATTGCTAAGGTTAAACGAACGACTACAAACGGAATCGACAGCACCTCGGTATGAGGCTGGTGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGATCCTTATGGAAGATTTTCAAGAAAACTGTTCACTAAACATAGCAGTGGTGTTACCCGTGAACTCATGCGTAATGACTTAACAGGAGGGCATACACTCGCTATGTCGATAACAGCTTCTGTGGCCCTGATGGCTGCCCTCTTGAGTGCATTAAAGACCTTCTAGCACGTGCTGGGTAAGCTTCATGCACTTTGTCCGAACGCAACTGGACTATTGACATAAGAGGGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCTTGGTACCTGGAACGTTCTGAAAAACTATGAATTACGGACACCTTAGGTGCTGTCGATTCCGTTTGTGATTCGTCTGTTTAACCTTAGCAATGCGTAACT ++ +*.*,2371=BB@>Q9A&-6:7?=;;::;6;221CEA?A81*(*1.)*007CEC775%%,*'?@B:=A==:9998=>8(($(5+;<>7.C3HL96=GAEEAA?BDCBEA:>;<443///-16>@AB@&&.&.>>/13'&49<=77+,+084-*,+$$%)'+2344/5?.;9::89AF=?>65?>BC5:?C?CEB>>:==A64))'*+&*$$$&/3464:DBB986>8;5.';=9;??06(=;:4766IJ>B6>*,//15ADB=@B@8$$86/0&%0,-;??@($@>A@E;/--,.'97A8ABCDDAB@F>;9;;=?6>/6+56/...1241$($6:7@DAHBA8<773,)25907---+%/,0-*9@?>9=1@9<:B>>ABBB@?B8=9;1,*$&%**2>6;IID@?,/+,25878%%;<8531( +@SRR11410539.2351902 2351902/1 +CAGTGACCCGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGCCACAGTACGTCTACAAGCTGGTAATGCAACAGAAGTGCCTGCCAATTCAACTGTATTATCTTTCTGTGCTTTTGCTGTAGATGCTGCTAAAAAACTTACAAAGATTATCTAGCTAGTGGGGACAACCAATCACTAATTGTGTTAGATGTTGTGTACACACACTGGTACTGGTCAGGCAATAACAGTTACACCGGAAGCCAATATGGATCAGAATCCTTTGGTGGTGCATCGTGTTGTCTGTACTGCCGTTGCCCATAGATCATCCAAATCTAAGTTTTGTGACTTAAAAAGGTAAGTATGTACAAATACCTACAACTTGTGCTAATGACCCTGTGGGTTTACACTTAAAAACACAGTCTGTACCGTCTACGGTATGTGGGAGAAGGTTAAGATTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTTAACACTTAGCAACTCTTAA ++ +.*0534421&/1)12=>;67A?.:779?C?BD?<884.--,'-2331(,1888=A0->==;96.:66=<<581003CB>?B@E@A?:=>::@EABD?A84:DEG=B9:88==II32ECAE@?A:@AA@:<=6.-'78:7;78),8?A94B20@??25;36?BG;>>A?>>;>:>6797@@FDF4?,;E=EF8FA>F(@9B:103685::;7;=A8:A;>66>?=56@?@:;>.'69.8B669;<4',237@CE<6,&8,<>-8:430+8<>8859((,,*53<147=9''?550)9&%4>27JD?DDD;<9ACF-',-*'(*=<3302:BBBBBBA@=@:7'(+'$%'0017778HI=C?;=<8<57.-.878=88-,C8@FB>@=99+6(/;&H46*+.'&,<>BA?BAA==<>6.,.%##%)%''&#'##$## +@SRR11410539.1038477 1038477/1 +CGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCAAATCGACAGCACCTTCAGGTGATGGCACAACAAGTCTATTTCTGAACATGACTACCAGATTGGTGGTTATACTGAAAAATGGGAATCTGGGTAAAAGACTGTGTTGTATTACACAGTTACTTCACTTCAGACTATTACCAGCTGTACTCAACTCAATTGAGTACAGACACTGGTGTTGAACATGTTACCTTCTTCATCTACAATAAAATTGTTGATGAGCCTGAAAGAACATGTCCAAATTCACACAATCGACGGTTCATCCGGAGTTGTTAATCCAGTAATGGAACCAATTTATGATGAACCGACGACGACTACTAGCGTGCCTTTGTAAGCACAAGCTGATGAGTACGAACTTATGTACTCATTCGTTTCGGAAAGAGACAGGTACGTTAATAGTTAATAGCGTACTTCTTTTTCTTGCTTTCGTGGCTGGATGCTGTCGATTCCGTTTGGCAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +'#$$558/6DA3):8=A:?HGDEBBF>>-FFBAD@=./;6@>>=<:;:(,',9>@>@>E?EE?@B>9;88@769:816>22://+&?+EB?9A677>?FCCDA=A=?EFD<=:=>/1<@3..;@D;AIFC?9;;<8F@JMD:7666;151CBA8<<;;=4552A1E@B??=4EDHBB:>CA@/>::@/@&&&(.--4+?;;C>86:7;>@BA:>D@A@E?9BC?DAC?;;CDA:<;?AEBAAB=ABAJBA:999%)/&+:>@;BLICA-.E683@FI@II?A''46.79<@GGHF5>;;;;9,577CADH?>BDE@@>AE=@C=21(-7DC:>;HK<;45=6<<:?<==><<;4.<;@::B=?@@<=:59??<>?;6:<07$($$$%%$7643D@:=;FA>=@D@>C??41<=>BDAB=030-'$$%5:0/&&$&*-$64;5:9BECHEBD-&%%&8@>>AA?@?=''=B;=C??>>)6=96'1# +@SRR11410539.1390629 1390629/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCTGTTTTACAGGTTCGCGACGTGCTCGTACGACAACTGGAGACTCCGTGGAGGAGGTCTTATCAGAGGCACGTCAACATCTTAAAGATGGCACTTGTGGCTTAGTAGAAGTTGAAAAAGGCGTTTTGCCTCAACTTGAACAACCCTATGTGTTCATCAAACGTTCGGATGCTCGAACTGCACCTCATGGTCATGTTATGGTTGAGCTGGTAGCAGAACTCGAAGGCGTAGTGGTCGTAGTGGTGAGACACTTGGTGTCCTTGTCCCTCATGTGGGCGAAGCCGATGCTTACCGCAAGGTTCTTCTTCGTAAGAACGGTAATAAAGGAGCTGGTGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGATCCTTAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +%*+24.;>?CCH=>4AED@@?B>>>74/2(BQDAC2=>>@=>994553437/0.7<H4)1/&118?:??9116:/53:;78EF>BC@LNFCAF><50(69:=EHDMGDADE@?ADD=??2M>%1*&>53&'$$%(&(1%%>?A@@:?0+(,;:)'*9+,3;>AA5@B@<69@E;31:>89AB:@CB>?:986-&&%&*'$$$%%(,$)79+%''+0.&$''-//-,*06,-3?H<===?BDCB>++-2/-,5:9??8J.0A1<>;99>443/-57<:<;=33:?CBEB8:>AB9<8@=@A6,*<=;377=C@34(.../056(*:;7''.(,&'.5===@61D@?AC?A?JDK@@>@:@-):CB@BFEHDA@;633=?CJDE<52% +@SRR11410539.921407 921407/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACCGAACGACTACAAGCAGATCGACAGCACCTGGTGTTGTTGGAGAAAGAGTTGAAAGATATGGCGACAGCAACCTGTAGAAATACTCCAAAGAAAGAATCAACATCAATATTATTAGTGACTTTAAACTTAATGAAGAGATCGCCATTATTTTGGCATCTTTTTTCTGCTTCCTAAGATGCTTTTGTACAAACTGTGAGAAAGGTTTGGATTATAAAGCATTCAAACAAAATTGTTGAATCCTGGTAATTTTAAATTCTGAAAGGAGAAGAAGCTAAAAGGTGCGGAATATTGGTGAACAGAAATCAATACTGAGTCCTCTTGTTATTTGCATCGAGGCTGCTCGTGTTGCTGATCAAATTTTCTCCACTCTTGAAACTGCTCAAAATTCTGTGCGTGTTTTACAGAAAGGCCCTTCTGGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTCAACATAGCAATACGTAACTT ++ +$$+-59655379B*0(28>A117578/0945.@9:784&,**.-0//--013&.))//08;+$..,--1799:041/0-./(64,$$$%&#$%%*&'')$$$%,(.&0)*227.*%%1?>;:58'0/-+&0*&'+&$6$'+%%$%%*)-+%.%&$*)&()/6@CD>@=:;924?*8:<<=8:;?AA6:A>>87+-.10,-+$%&%&&&/0//*%#'+++&0-1..&))(**&7:475F:4;>@A5;<3645:9A@@F@8+($&)&&&(-'+10/+0)$)*((12.$+980*352:GGI@<>@ABA04,-2.23467400124**2(*%&#&%+,/12;0.-'$&'00++--,/-(+(&')&''%''-/-+2+%*&%)**,*&++(:3@BD>>;>>=8:094;8DCDEK816..1+%)3-,##'''&(*>;=BA>AC?KC?@9?@D=91/-'%12&&& +@SRR11410539.1934526 1934526/1 +GTTATTACTTCGATTTCAGTTACATTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGTGTACTCTATAAGTTTGATGGTGTGTAACAGATGTTCTTTGCACTAAAAACTCTAGGTAAGAAATGCAAAAGTCACCATTAGTTGTATTACAGTAATATCGTGCCAGGCAAACCAGGCACGACAAAACCCTTCTCTTTATGACTGCAGCAATCAATGGGCAAGCTTTGTCTGTTATATGTACACCACGCTGGCTAAACCATGTCCAAAATCAGCATGTTTGTTAGCCAAAACAAGTATCTGTAGATGCTATGTCACGAGTGACACCACCATCAATAACCTTGTATCCTATATGATTTCACTTGAAAAGTCAGTATGTTTAGACATGACATGAACAGGTGTTATTAAATAGAAAATAGCAGCAACAAAGGAACACAAGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATGCAATAACC ++ +&%%'%*6888+0+?E(<8;:>@=**.95:ACH:;9DLIDG@=449;=9?@6;8:<:===B<@7DCDC>>9E>:8?9:A<:8B?<==999-*))+41:322/**,7%+115:@A?1689;45538;.89:50&&?:<>1+14*.,0/=?G>C::1,21409B=>>H)&+::>>>ED:ABG=<5=4.%$*000:1AA@=?6-A775$%/014>AE78;K@*:BEBADFFF?BC=AO@8;:@59EF??D<>==?<;>@@@--5560/33E?LOKNJHIG>76;2@E?721<('8>776(*C?@B97,-+;8;3?9><;929ACD@B9FEI93C7:7.9<::=@5((&'&(6''''))2%&&'(%% +@SRR11410539.1424426 1424426/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAAACAACACCTAATTTGGAAGAAGCTGCTCGGTATGAGATCTCAAAGTGCCAGCTACAGTTTCTGTTTCTTCACCTGATGCTGTTACAGCGTATAATGGTTATCTTACTTCTTCTTCTAAACACCTGAAGAACATTTTGTGAAACCATCTCACTTGCTGGTTCCTATAAAAGATTGGTCCTATTCTGGTTAATCTACACAACTAGGTATAAATTTCTTAAGAGAGGTGATAAAAGTGTATATTACACTAGTAATCTACATTCCACCTAGATGGTGAAGTTATCACCTTTGACAATCTTAAGACACTTCTTTCTTTGAGAGAAGTGAGGACTATTAAGGTGTTTACAACAGTAGGTAACATTAACCTCCACACGCAAAGTTGTGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTGGCCTTAACTAATAAC ++ +&($&&*'(/012<9,'87>DDEGGEE10C34/9A?CDF>9A@==<=?==FBIF@E?>CB@876;?BDD??7<68==<=?8=1:=;@A71:;<;?<>>>5(AFC>@BEE$698AA;::76=?75886<=9:AA/0ABAFK5%,--1%'''*(;@<70%)04=@=B<0,//)*:6C<=8>>%(5EEI>D<)+;6&,65=//3:>>@6C741,,,017?3410,4;:<<9;/6-+:97?DGG@?>?CAFB;A=>FB:;>A=B55C:>9@?E=@:87.///3858=7.))%.3)*4600;>C:A01,)6-0/$%25?:;;2367::?==<3&524/0795-24@<>?;7C>:FF:;0::IA:;9796==))2AB9'('%%*%(.+-+)*0225485950$$$%''#$%$*2,,("#$%&+*147*%$%$%&/5//:B=87=<79=567<8:2327,+-&'.12.)/07DC><>==>;552'95A@B?F<43;88:57%&&224><=B36+=%11?BADE:74445'*)/<;;;9B<474=453;=8-/15?@98?5DHCCD;11+/48:7798;;:?>5(&&,0))%),+(--=:;111'').)'(&0-10045++114845-.6;<;2563.+*+)(%&#%&$&,(-996=@?;5357-$/0%'%$%4600111?:;?@C8;=976.2(*.065-,1021+&#$('1756:B?@>9:BE<;5/0;EMKGKE.0+*%%%%>B9BDBHL=A373;8=BHBBEGF@@G>AB>856==?@>>78FGCHFCHFFKCB8578536,,+3..-5/@=4449;A@@:<9>?B>;FIG:8:34.''')*%*,22<965/(3:6337='*16GHDC>0B<>9=9CAC6=9:?8//A))+EC/=CCFBB:)&#&+1*78:5:D,?/*('.4560+B8<9;;==92&A,>ACECBAIABD5.C77@@:726$&$$(##%#$(*),44,?99:;H<()%$*&%%%(+)(8,(/:>@;;66@5)--8D>9:CEGC=ABA+C:<=@:85)-,1<=996=6>DB0+&%/');0//.156*0,50=;:::67().-17?=>&'&%%&*7)<=;;80,$'%%%((&$&+,+$ +@SRR11410539.1221028 1221028/1 +CGGTAATACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCGGAGAATCCGGCAACACCTTGGAAAAGAAAGGTAAGAACAAGTCCTGAGTTGAATGTAAACTGAGGATCTAACTTTGTCGGGGTAATAAACACCACGTGTGAAAAGAATTATTGCTATACGGGGAGTGGCAGTGAGTTCTGGTTGTAAGATTAACACTGACTAGAGACTAGTGGCAATAAAACAAGAAAAACAAACATTGTTCGTTTAGTTTATTGTTTCAGAACATCACTAGAAACTAACAACTCTGTTGTTTTCTCTAATTATAAGTCTACCTTTACTAAGAAGAGATAAAATCATATCATTGATTTGACCTTCTTTTAAAAGACATAACAGCAGTACCCCTTAATTTAAGGGAAATTTACTCATGTCAAATAAAGAATAGGAAGACAACTGAATTGGATTTGTAGGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +2$&*%&)*/3:9:@7)*-9;<==GHFH@??+(236:67012389CA?<=)2)-0/2:$$5$&8/0;>CCEE?A;@F'1C>41>;)).1)1+,.006989?D>;:?>;3)(%$',*<@=33((+-69C60;./+9136757;9?@A=AAA./#'DGB09*(2)8887A5237;339.+.00>??@@A@?9C?1./%+,'*+%$&%'))*>@A>CB==F@AD=599;;;=7635055+87=?@@0<:,,1((,*::<@CBB:A:BA@@77=BCIHEDA;?@E6OIN>DF-%,2123559673;8;9BAD;8BCECI@860(',478=C76;6>==9>@A=;BH220:9=;@*6DAB83.:<997<8;4:AF;.5+.8B:AB=8=A==>AC?HDL?9149949=:>?=122&)&'2%056=??553,& +@SRR11410539.811643 811643/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACCGATGGAAATCGACAGCACCTATTCTACACTCCAGGGGACCACCTGGTACTGGTAAGTCATTTATATTGGCCTAGCTCTCTACTACCCTTCTGCTCGCATAGTGTATACAGCTTTGCTCTCATGCCGCTGTTGATGCGCTATGTGAGGAAAGGCGATAAAATGTTGCCTATAGATAAATGTGGTAAATTATACCTGCGATATGCTCGTGTAGAGATGTTTTTGATAAATTCAAGTGAATTCAACATTAGGAACGAGGTATGTCTTTTTTGTGCACTGTAAATGCATTGCCTGAGACGACAGCAGATATAGTTGTCTTTGATGAAATTTCAATGTGGCCACAAATTATGATTGAGGTGTTGTCAGTAGCGGATTACGTGCTAAGCACTAATATTGTACATTGGCGACCCTGCTCAATTACAATTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCGCCAGCGGCTACGT ++ +&(*00-46>>>>9A@8B;:=<<;/24-$4,=993441./-.%+8;>FJI;<51-&8@8330&*/)1,6>4877?<)5(,'''/;=77?EDBBH==?A,8&7%(#($&$%,--((,54:<8:BDF88CA9:94840%#%%$$+04(533$+(-'(9=A@D%%ED<==?<>7:;6*-88=<168+*%*005.++;((%#)'$'()/(7+(&.%*'96?><;9CGF@>=KDD622=862GJF@@B442&-,%-,*'%1=72445<:551/&%$$C>?73@?BC88ABC@?+8%%-.1)789%%%&$$$,124@AE=12(?<7+3:<>=>7/1)'(&&'%*)55&%$&'').003**+'+''&'$+6>74<8=<GF<54*+%&&*$%#$%)12&$ +@SRR11410539.1713855 1713855/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAGCAGACGACTACAAAACGGAATCGACAGCACCTTGTTAAGCGTATTTGACTGGACTAGTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTGTAGAAAGGTTCAACACACATGGTTGTTAAAGCTGCATTATTAGCAGACAAATTCAGTTCTTCACGACATTGGTAACCCTAAAGCTATTAAGTCTGGCCTCAAGCTGATGTAGAATGATGGTTCTATGATGCACAGCCTTGTAGTGACAAAGCTTATAAAATAGAAGGTATTCTATTCTTATGCCACACATTCTGACAAATTCACAGATGGTGTATGCCTATTTGGAATTGCAATGTCGATAGATATCCTGCTAATTCCATTGTTTGTAGATTTGACACTAGAGTGCTATCTAACCTTAACTTGCCTGGATTTGTGATGGTGGCAGTTTGTAGGTGCTGTCGATTCCGGTTTGTAGTCGTCTACTAACCTTAGCAATAC ++ +$$237:6>AC?AQ591==7689B?CFD?GBFD89<*%/'),?A@>B>A,(,'$5=>D?B66:A9=9:9=3372>@//59>DAAAFF>G<=A4+5&--%*@D+9%%39&%A>E7>GI@EA89%>@B=EEEG@E:-67>6C=<>GC,6474:@?>'%&8=.AEF39?BBK90=GIA=?9002+,$'#+*)+-*=<=C?DHFBA.:*0,-*'%'*79:3.8=?DCDE;>@?A8>4*3+CB@B@A95++1=>DFFH;@5:&35:8B4C8EAA=DFCBC=>9'>ED>4A5>CDCED@?B=D?>A>34>;238*:61*@>>345:C?E==:5@A;A58/3?A@CE>FEC951/.(.9BDBCB=?66AHBBD=9B?DB5555...499>?B()%6888>A>I=@A984+:.0G<<>A:=66608;86DC7@=AJF<599:8=655,%'*55?AE3'68013,( +@SRR11410539.1547229 1547229/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGGCGACTGGAATCGACAGCACCGCCTTAAGGATCAGTGCCGGCTCTGATCGCCTAAGTCAAATGACTTTAGATCGGCGCCGTAACTATGGCCACCGCGCTCCTTTATTACCGTTCTTACGAAGAAGAACCTTGCGGTAAGCCACTGTTTCGCCCACATGAGGGACAAAGGACACCAAGTGTCTCACCACTACGACCGTACTGAATGCCTTCGAGTTCTTGCACCAGCTCAACCATAGCGCTGATATGAGGTTACGGTTCGAGCATCCGGAGCGTTTGATGAACACATAGGGCTGTTCAAGTTGAGGCAAAACGCCTTTTTCAACTTCTACTAATTGCCATCTTTAAGATGTTGACGTGCCTCTGATAAGACCTCCTCACAGGTCTCCAAAGCCACGTACGAGCACGTCGCGAACCTGTAAAACAGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +%**+'+'47;8:@91,8:@B7414=AA;<<=-BJF<>,2-4760/)&$&&(68AA*&<:>3-&66>@@<(D1++'+8--,#%&')#&&:??@A666.7;9D<4ED580)-733:116?A@?73+''&#%(**))7@B9A;A;?583$7:FIDII65:980))-B>=9EG@A=@?=B577=77),-23*++(25751/0151/?>&?BC=00?+,,?;5;EAGCCE<<;44('+34<@BEEE15<<=6-/(:60,$$'()+071?>1-.==4,0$&/*0.*%$-/&$=(,&<*.:;:88AC@'':'(&'8=@@?0/887:9,2203439;59EB=)+*96:+0469::15>?@>?CA-?()226A7B<7+)%(/45@>@IE@./1(5::<>977C@=;4B5559679887:4;)><0)1>;>C0A7999C?+8::77<7778=51=11313.0,-%4756/0-=21=5-<755617=GBD;>AB;=;K1?:=FD?2*75;8/5;%&*&08;9:234.=@BEG@HI?B9?:?::8?658C?<>90/+-'%%%8;36AB>2+'),+32CCDJABDQBC=?445=5=:A@G?8=5:>A@A552/**(''&5502(0446;7:=<9EHHG9;67..9=@>?507)@7=:;DBDC>CDAK@CBECF=2<3.5'('(<95*)24EBCBB(11)*5687=68-*&&*.(7:2+01289689+'/*'(5.0;;=;?@<5=>>)(6;<5$&%9:=@?;>BD>0/),0*&654*5733)+683@6:=,,,2503)1>71,))*1>>G>@A23*+%*=9--@<3@CCE>E8AA=?=?>9@?;>ID>9?AEDH@>?PEB,-)8&&/.1&''1173?CA?>-%82++//002->E<<>150)+><>D>:@=785:B;:ABC99:462/*'('')-*%'((+' +@SRR11410539.378820 378820/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACTACCGGTTGTAGGGAAGCATTGCTACTTAAACCAGCAAATGGTTTAAAAATTACGAAGAGGTTGGCCACACAGATCTAATATGTTGCTTATGTGAACAATTCTAGTCTTACTATTAAGAAACTGTGAATTATCTATAGGTATTGGGATTTAAAACCCTTGCTACTCATGGTTTAGCACAACGGTAATAGTGTCCCTTGGGATACTATAGCTAATTATGCTAAGCCTTTTCTTAACAAAGTTGTTAGTACAGCTACTAACATAGTTACACGGTGTTTAAACCGTGTTTGGCATAATTATATGCCTTATTTCTTTACTTTATTGCTACAATTGTGTACTTTTATAAGAGTACAAATTCTATAATTAAAGAAACATCTATGCCGACTACTATAGCAAAAGAATACTGTAGGTGCTGTCGATTCCGTTTTATGAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +*&))1329:;69L==5:DIHAAIHDE@?988''3;=DFD1212>EJAAE:;<,4$'$.53&%&48=?>=90++%$/#'05/%*(''&#/8,,/)252..5BD;5)%%&*+)&''/236676688+(011--2987*))*34BA@?,&>+)*),%%*/89?@;740&&035615@A=?9=?A>CH;=@<>9943$&+&=IHHED889A@BAGK9CA5;;831*;?9?@;<1*&4747-%245HG@?8/.,%,%(%'8D<8-'''*$'EGA.355=B?@>>%%A@?G==7@HD3;-.CD0&(00,++4329.3@AA<4.<=@BE01+.4:+%%$$(8;<6@:7@>500'($&035<=ACJEIB5(+ +@SRR11410539.2197758 2197758/1 +CCGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAGACGGAATCGACAGCACCTTGGTCAGAATAGTGCCATGGAGTGGCACGTTGAGAAAAATGTTAGTTTCTGGATTGAATGACCACATGGAACATACGCGCAAACAGTCTGAAAGAAGTAATGAAGCTGAGTACATCAAACCTACAGACAAGCCATTGCGATAGCAATTCCACCAGTGATCAATTTATTCTGTAAACAGCAGCAAGCACAAAACAAGCTAAAGTTACTGGCCATAACAGCCAAAGGAAAATTAGCAATTATATACAAAAACCTATTCCCTGTTGGCATAGGCAAATTGTAGAAGACAAATCATGTAGAATAGGAAACCTATTACTAGGTTCCATTGTTCAAGGAGCTTTTAAACTCTTCAGCGGTAATAGTACCGTTGGAATCTGCCATGGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATGGCTT ++ +3+)++22.4245.)3:@@>;7634326%&1986/1*2769BAE>AA652?<<96:-/69D47G@E@IDFD<:675:@?A91@:D;9/&..,)8++:2+6EBC=:47++195:*:<@<0D3@AC>84&'096>3@EGB0+-&=)./=2%((*(6:7013-326+(*'+3/9,0$346,)/(60-/.><..10;:A.@()-.-0'('),,-<8,'09;:.158*,:12:;BA@=?=@3>;A<9611=78/77526F?@?BFC@DC<<<>>;@>:??;<'2&%A:9:&360412//243.2';8::=?8<>:7355=8;5;>95686?D??9?9F8@>>=@52@8;??-3)$$$.0/0//*&&### +@SRR11410539.1225701 1225701/1 +CAGTATGCGCTTCGTTCCCAGTTACGTATTGCTAAGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCTGTTTTACGAGTTCGCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGAGGCACGTGGCATCTTAAAGATGGCACTTGGCCCAAAGCGGTAAATTTGAAAAAGGCGTTTGCCTCAACTTGAACAGCCTATGTGTTCATCAGCAATTCGGATGCTCGAACTGCACCTCATGGTCATGTTATGGTTGAGCTGGTAGCAGAACTCCGAAGAGGCATTCCAGTACGGTCGTAGTGGTGAGACGCGGTGTCCTTGTCCCTCATGTGGGCGAAATACCAGTGGCTTACCGCAAGGTTCTTTAACTTCGTAAGAACGGTAATAAGGAGCTGGTGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGATCCCTTAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTAACCTTAGCAATACAATAGC ++ +,''.'%$##+9<>=E7&*'$)76,.(;;;84.%#$/)-8;8@11;+9697-146*6',24:;<;9C<<8>=AD@??=@/$&&&,3*9%('.*)(&,->:62625/D@A**0?9EAC=EBE@@<74'%.3327>9=65256202++*()5BFEAECD8:=<@:=>@=@?8302%-*((+*''42:52;/@BB'8-,')06DHDG1&805=9A8D:=;;;B>AC8A45,(%%14;::D@@>;>;2:==:((2<@A?=@>HDGCNE20078:;+DI?<<;*566;==99=;?CIF%0;''')*(-(;>===?>@?>56/BA@5C+3DGHDF@7@8;>42@G9:1032=<<;5:81129700;--200.;CDBC=8ABBG@BDDEA>IH05+(/23-67%+5=;88)HG@><.7?8:3+.1.4,&(353++*982>E;E4<=CB@C>DEBBGBB:5:3//0,'99@E@@BFF@:6//-..88:5.++#&$-:;>=?A>@DD+0776@A@@@CDG@AC=>;8-'(-+79<8679.>=''+>?ACEEIB>:H>;:>268DA>@?@C?=>B@@@27CCEFG9;=?B>?@@A?6>9;=>@B;IA9=B@A:<78=B66@=>;@=344=D@,,<9@DKBHF?='7&')%70406'75:79GE?FB93CECCBC@F<;IQ@2?CB<>0AABD;=IFB>F?3328;B:'DJGH88E8?5(&;?BEMK;>C=?9;882(4ADEB?H@?=%%($$8ABCECBCB@86*$$%#$001;=?@D<9-1& +@SRR11410539.853615 853615/1 +GTTGTACTTCGTTCAGTTACGGCCTTATTGCTAAACAGACGACCTACAAAAACGGAATCGACAGCACCTAGCCTCATAAAACTCAGGTTCCCAATACCTTGAAGTGTTATCATTAGTAAGCATAACAGAATACATGTCTAACATGTGTCCTGTTAACTCATCATGTAGCTTTCATATGTATTGTAAGTACAAATGAAAGACATCAGCATACTCCTGATTAGGATGTTTAGTAAGTGGGTAAGCATCTATAGCTAAAGACACGAACCGTTCAATCATAAGTGTACCTGCATCTGTTTTTACGATATCATCTACAAAACAGCCGGCCCCTAAGTTCTTGATGGATCTGGGTAAGGAAGGTACACATAATCATCACCCTGTTTAACTAGCATTGTATGTTGAGGCAAAATTCATGAGGTCCTTTAGTAGGTCAGTCTCAGTCCAACATTTTGCTAGAGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACATGTA ++ +$$$',+11102361-<94+3'(%$'.,,1652:>)($)$--/(%(/3575938264>;9>E<8A8>BB/)<78'>*6>@ED@+ACDIMF56BFIEA?@ID=<77=:>@B=C?D?45=B@;=CCAB5:415//69;>=>?@BG?9:;9&&)*)$+36580>;;F<<1B19;<9*#)99@I324;(%8%%%5314@9=?<88=7CE>FGHHC>;50/%@94CBFD;DCCACC<8EE@893)02:=547<>>FACCF>@2:67/=:832/'(38?BC>DADB;7688BD>>?:=0)268@D<<::403-*((+'(3'0BJHFCA<=E7C89>2311/?4599=96+(7+A9A;>:;6A<>,,A9:ABKJUMBA>=:%7B;<<40><:8<68<@=JBDD@:?<>@=A>>812/2/1)23/*&%$(%$"% +@SRR11410539.152875 152875/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAATGGAATCGACAGCACCTACTTTTGAAGAAGCTGCGCTGTGCACCAACTTTTTGTTAAATAAAGAAATGTATCTAAGGATTGCGTAGTGATGTGCTATTACCTCTTACGCAATATAATAGATACTTAGCTCTTTATAATAAGTACAAGTATTTTAATTGGAGCAATGGATACAACTAGCTACAGAGAAGCTGCTTGTTGTCATCTCGCAAAGGCTCTCAATGACTTCAGTAACTCAGGTTCTGATGTTCTTTACCAACCACCACAAACCTCTATCACCTCAGCTGTTTTGCAGAGTGGTTTTAGAAAAATGGCATTCCCATCTGGTAGAGTTGAGGGTTGTATGGTACAAGTAACTTGTGGTACAACTACACTTAACGGTCTTTGGCTTGATGACGTAGTTTACTGTCCAAGGTGCTGTCATTCCGTTTGTAGTCGTCTCTATTTAACATGGCAATACATGTTT ++ +)/0696<=>?@M972?IEB@8987;-:7//'7-7DHJ8D9C@BB><55//+&$''3>@AHECIJBFDB>8=BG;532/32'<@8B88<.D;:425$$&./;<@BHEACE>EH:+11@<>CD?C=??%?+EKEDDBG?B9;@(><@@9971&$.>==::=GHFEK=&&&)7:78@@DCBDFA?>458?F<=<>8D5ABEE?@=;>A>55./,.054$:AABFH/(,,?7:712A9@==CGE>BBCEGHDGE=?EDF@76=73@402+9))79:<402>J208829<>H@BC7F?@DOL>;C88=;1256<=@99>?EEKFTIEBDHD9@>DAHAA9;@=88?><6>C@>B@GEKA<8778404-'()00.00.(/&.6661/+/&$&&% +@SRR11410539.2484305 2484305/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGGAATCGACAGCACCTACAGTATTCTTTGCTATAGTAGTCGGCATAGATGCTTTAATTCTAGAATTTGTACTTCTAGTAAAAGTACACAATTGTAGCAATAAAATAAAGAAATAAGGCATATAATTAGTACAAACACAGTTTAAACACCGTGTAACTATGTTAGTAGTTGTACTAACAACTTTGTTAAGAAAAGGAAACAGCATAATTAGCTATAGTATCCCAAGGGACACTATTAGCAGCTAAACCATGGTAGCAAGGGTTTTCAAACCTAATACTCTAGATAATTCATTAGGTTTCTTAATAGTAGGGCTAGAATTGTCTACATAAGCAGCCATTAGATCTGTGTAGCCCAACCTCTTCTCTGTAATTTTTAAACTATTATTTGCTGGTTTAAGTATAATGTCTCCTACAACTTCGGTAGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACTT ++ +*++(*)57::=D8/*6+/<63443617812/?HEFJAAB?F;=94/7:?A=*$7;<;..<=87))<>=06756DAB>76@E?CG,=BGDGA;B6>B;859:53/0@8ADCA?1<,1>BEL??>9;=>@@99FGH@;EA>H;21(+196?>651)+),.=;2+11B9<=<=?BBFB>?828-?>>=@?;8(&<78;?NF@76/6=9:1249743/-/'**4,08<;8-.+*%%$%'589;22(35/*&&)'&*0-19?EFII@CCB=ACCEE::>845+;?54951)$$)(115=0CE;<@?:$*281512:%;CCO6?110=&:DHG?=<@:>B?87)6&)%3,8&.9@ED=>===<9-.56:205%%+)3..71054)%%&''...47AD8.%,6<@CDDEQOE@B0<1EFB8C>QEJI>@LK=23(,.1:>?B<=C8?B;:=:))D8>=;129A63?BDD:48:...699DCE=BED;>?>B=ACDD???>;<=<=BBADD><98$$& +@SRR11410539.378851 378851/1 +CGTGTACTTCGTTCAGTTACGTATTGCTAAGGGTTAGAACTGACTACAAGCGGAATCGACATGCACCTGTTGAACCTTTCTACAAGCCGCATTAAATCTTCCGAAAGTTCATCACCAATTATGGGGATATTCAATAGTCAGTCAACGCGCTTAACAAACGCTGGCTGGACAGCTAGACACCTAGTCATGATTGCATCACAACTAGCTACATGTGCATTACCTGTGGACTTGACAATACAGATCATGGTTGCTTTGTAGTTATAAAGCCATTGTTTGAACATCAATCATAAACGGATTATAGACGTAATCAATCCAATAGAATGATGCCCGCAGGCATAAGTTAATCTGAAGCAGTGGAAAGCATCAATGGCGTCTATCACACCAGACAACAAGGTGCGCTCCAGGTCCTATTTTCACAAAATACTTCACCAGATGTCAACTCAAAGCTTATGTACCAAGGTGCTGTCAGTTCAGTTTGTATGGTCGTCTGTTCCAGCTATGTTCGCTACGCTAACATA ++ +&%($$$"#$&)()($/.-%1./001('-'('+7>6---,),75?>9;79%;*,,0*2-,+&#$(+00-+)&%%&(,(..2)&$25,33%)$##'+*)-$(#&#%%%,9<:85.',,')'*((&*794($$%'%%'&.&6-9=@C@?7;:9=>;:6@F??G=@>=@A==<<4<>@CCD776)((*+&9;=:NJF@@:<=0//-(//43+/EE3../2,'%(*+'-01,$,%+$*(15?:><368565.-/--,.814,,?=>9264?6-/3-1/#$%%&1:01021,2-,)*%&-2,-,):*+**'&,&$$%%($&)-44+)-6.2&#&01:9((0&&612-(/8=%41-79;=>5GGL>=990$$$%%$#$####$)$/%%*%$&%$%&&%%&''$$'.%)+*(&&&%&'#$$#"&#$##$%#"%#%%$---.'($ +@SRR11410539.1346832 1346832/1 +CGGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTCAGGTGATGGCACAACAAAGTCTATTTCTGAACATGACTACCAGATTGGTTATACTGAAAATAGGAATCTGGGTAAAGACTGTGTTGTATTACACAGTTACTTCACTTCAGACTATTACCAGCTGTACTCAACTCAATTGAGTACAGACACTGGTGTTGAACATGTTACCTTCTTCATCTACAATAAAATTGTTGATGAGCCTGAAGAACATGTCCAAATTCACACAATCGACGGTTCATCCGGAGGATTGTTAATCCAGTAATGGAACCAATTTATGATGAACCGACGACGACTACTAGCGTGCCTTTGTAAGCACAAGCTGATGAGTACGAACATGTACTCATTCGTTTCGGAAAGACAAGGTACGTTAATAGTTAATAGCGTACTTCTTTTTCTTGCTTTCATAGGTGCTGTCGATTCCGTTTGTAAGTCGTCTGTTTTGAAAACATAGCAATACGTAACT ++ +5$(%,--;==9;M.5/<@@=B?D??D@AC66-BCCDH6?:9=A9:7676FG@>;=FD?==?;97B@@BA/0*9=@8=B?@;99**4231+&8,CGE06,33=>AJEA:1))BDB<;>>@@B:3+*(&(*03(-4CB?:.51,9;DA@=;4++,7<=<6CA<40125868/0.4&4/423@=7@4@DDC>8=?BDB2>999;776?@@>A=998956@>?ECHL;AFJBE''?33/77-6>7:=AE::/'4877GFIJF49()(-75878=<;BA>?>B?A@DCCBFGGLA?;GE>@?FI88/040)5894ACIHA@>AFA876(&>>CC?=D9217@AA;886>;;31;<=5116=?@>?@1)))($%%1233AB;=EBB91#( +@SRR11410539.1236160 1236160/1 +CATTATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACGGAGCGACTACAAACGGAATCGACAGCACCTACTACCGAAGTTGTAGGAGACGATAAACCAGCAAATAATAGTTTAAAAATTACAGAGAGAGTTGGCCACACAGATCTAATGGCTGCTTATGTAGACAATTCTAGTCTTACTATTAAGAAACCTAATGAATTATCTAGGTATTAGGTTTGAAAACCCTTGCTACTCATGGTTTAGCTGCTGTTAATAGTGTCCCTTGGGGATACTATAGCTAATTATGCTAAGCCTTTTTCTTAACAAAGTTGTTAGTACAACTACTAACATAGTTACGGTGTTTAAACCGTGTTTGTACTAATTATATGCCTTATTTCTTTACTTTATTGCTACAATTGTGTACTTTTACTAGAAGTACAAATTCTAGAATTAAAGCATCTATGCCGACTACTATAGCAAAGAATACTTGTAGGTGCTGTCGATTCCGTTTGTGATCGTCTGTTTAACCTTAGCAATACGTAACT ++ +(%$&(%%-./36=:=35=@.BDA?>B;>?AA+@DD88-6$)$$58=<=408908')+><@?>7>CFGPE@A;<07873**.$+&,+'''61,=++:;?AFHABE@F@89CC>@>9:<:7?0:BA<;99KJHCIJ??>?<0:<>::++AEBBCADAB?;6+@B9=C@EGH?55?<145-,4#&==;@/*6989?89:*.8<:,(05329..0*.*,=8<:@++)252@C@??KF321><:>9?69>B>97?67AEC;D:7/+;---2-**0.968=AD5HF?DC?>@,2/,+&'$'.,&$$4786.=@6,--*&',/AA>IDIHB8;<8<<087:<@CKB8:8<0-6&1)8>CE><6.5&8801?@+*<<:BA=$$6)&658130)*3+2BB-':<32,/4&0635??>BD=A@>?2369A;3+,#$8;:>@:=8;;4-6675('(*)'''01/05,2.'&+'(%'*+/%++8:*@065430/+')-;2.:<<0956-4145+19..10./222+1'064--20.;;D73A@;56:;<;7;7875735B<:9925''.''%"&)&*.2:5>22*)500.'':230)1/29$+975120-/,.*)&*+.*0+5&9C@<9:?;88:>7::>@,209=?@;9381)+;@@DF>85901--'054$+'1&*'--731,,6>>@AB<:8C?>>>9118=88/)301B7;>?679=?5=.(.3=>=AAC//ADBICEC>=2).((-974<4==;5:52'%$,CBBD?;EGDCA137:96)'785A;7D..-.&()$($%%##%-.*)1$(,-&& +@SRR11410539.2477472 2477472/1 +TCTAAGTACGCTAGTTGATTACAATATTATAGGATTAAACAGACGTTTCGACAGATCGACAACTTCACCTCATCTTTAAGATGTTGATGCACTCTGATAAGACCTCCTCACGGAGTCTCAAAACCACGTACAGTACGTCGCGAACCTGTAAAACAGGCAAACTGAGTGGACGTGTGTTTTTCTCGGTGAGAGCTCCAGGAATAGGGCTCTCCATCTTACCTTTCGGTCACACCGGACAAAACCTAGATGTGCTGATGATCGGCTGCAACACGGACGAAACCGTAAGCGGCCTGCGGAAGATAGACGAGTTACTCGTGTCCTGTCAACGACGGTAATTAGTTATTAATTATACTGCGTGAGTCATAAACATGCAGCCAGGTGACAACCACCTGAACCCTGGGATCGTTTAGAGAACAGGTCTACAAGAGATCGAAAGTTGGTTGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTGAACCTTAGTAATGCAATGGCTT ++ +#####$##"##($#$%%$(,$,$$)(+,'(%'&#%(((--',&$'#$%'&)+*//01,($#$"##+$14584<>=;*./0,$&*&&#/&3$$5:0**.&'.5428(0.1++&.&6780;678'7911,/,,'(&+-(%%%%+)+887;19:731-14=8;75373+5,1/41?:82;;<;2)+5$%)*&%&$##&*()$%*'*)*&%&&-1<6;A8,$%*$&/9++*5)()*5%*.')*'*21)%,.)''&$%(%(&%/5+256875;8@%.3,-%.+667((-,.,1,&%%%+1-*/()('&())%($$$(&&(+'(*-1(-%&%%(*-+)'&'('*'+5++-&-/,)*-,**+**%(+&.2--)++(,3*+*&&-<+2<>-23,1180::0*@>99;=A:9;7))*/4968?<<:8.%-',+)*%#%+,,+,$$(%%"#$ +@SRR11410539.1642578 1642578/1 +CAGTGTACTTCGTTCAGTTACGTATTGCCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTTGTTAAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTGTAGAAAGGTTCAACACATGGTTATTAAAGAAAGCTGCATTATTAGCAGACAAATTCCCAGTTCTTCACGACATTGGTAACCTAAAGCTATTAAGTGTGTACCTCAAAGCTGATGTAAAGGAATGGAAGTTCTATGATGCACAGCCTTGTAGTAAAGCTTATAAAATAGAAGGTATTCTATTCTTATGCCACACATTCTGACAAATTCACAGATGGTGTATGCCTATTTTGGAATTGCAATGTCGATAGATATCCTGCTAATTCCATTGTTTGTAGATTTGACACTAGAGTGCTATCTAACCTTAACTTGCCTGGTTGTGATGGTGGCAGTTGTAGGTGCTGTCTGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATCGTAAC ++ +*%#&(*+&&+)29+=7=DEF98<<8;51%$$%.@NFEE>6,/.5;:>A8399*'&)-.=C?E@F@II@AHJ;DE895=;CEEDD>CF>ADAA>8;8;DD@44560/%&%(%%7>?B@@C74242&1592511B<@DPLA=336B*0FE5<69@@D:@7?@0&65:;26533;CB;GFEE<<>3$*)(')*/1?A68@BBFEDG=0/.?<:7ACJE>;0,/01+&-3.,:586@343,=:=750-%&%)(/=:56226;94*&&%'3357:?:@ACD4,%)(,.,'555=>?AB@><0/8??A6.>@;><>@ABA1(27:=B:66:)-.41:;6:>B?<>BEDIDHDI>;B=;;B5?=A?>787>?B>HEH::=GCDHBC9=(1>BE=A?A47/0$146=>ED?@B<;@H>>E?>/3400.)898C4480),'24?>&('+.D;=<;76210$$)+'+,(+(.0--+,#$%$&'% +@SRR11410539.20470 20470/1 +TGATGTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAGCAGACGACTACAAACCAGATCGACAGCACCTCATTTCATCTGTGAGCAAAGGTGGCAAAAACATTAAGGCCGTTCAAACTTTGTACGCACAAATGAGGTCTCTAGCAACAATATCACCAAGGCAATCACCATATTGTTTGATGAAGCCAGCATCTGCAAGTGTCACTTTGTTGAAAAGTAGATCTTCAATAAATGACCTCTTCGCTGATTTTGATGAATCTGGTAATATTTGTGAAAATTAAAACCATAAATCTTTAATTGGTGGTGTTTTGTAAATTTGTTTGACTTGCAAGCTTCTTGGGTGTTTTGTCTTGTTCAACAACTATTCCAGTTAAAGCACGGTTTAATTGTGTACAAAAACTGCCATATTGCAACAAGATTGCTGCATTCAGTTGAATCACCACAGGTGCTGTCGATTCCGATTGTAGTCGTCTGTTTAACTATATACATAATTT ++ +%34&&8%89;<>A>>+8.2)''.,-25?@>?5-57>)5.0=8??E>>@CCBAHB9@EJB?>F?<=;8@996&+09013.35/+.*%'/00,,-+--&')%;==7*+$&+..1/1<3811?58-8*/'1%%/>A>4/2'%.$%('2--.0202265CD=DDCB@852),.),*;A?EIAD:=:52)*%&0>AJ9AEE?>@C=::B<;=8-%#"(*$$)/'%4+,%-7A9.0<:733@DH7===?:235;<@279*)&,;>@SPI@BCC;?>48ABCCNL?A882?DK@@CB<7&&&%%01)<88%&&+$$%+2;?B?>;@A9015&&,>@=A(.23JGDE99A>CC?HG;22.4>%87;@BB6..481<=9B12-55=AAFA):A5;2?BAEC++)$%*3,22:=778,,01-011++(%'%'&%$$##$ +@SRR11410539.860199 860199/1 +CATTGTACTTCGTTCGGTTACGTATTGCTAGGTTAAACAGACGACTACAAACGGAGATCGACAGCACCTTTAGCTTGGTTGTACGCTGCTGTTATAAGTAAAGGACAGGTGGTTTCTCAATCGATTTACCACAACTCTTAATGACTTTAACCTTGTGGCTATGAAGTACAATTATGAACCCTCTAACACAAGACCATGTTGACATACATTTGCTAGAGGACCTCTCTTTCTGCTCAAACTGGAATTGCCGTTTTAGATGTGTGTGCTTCATTAAAAGAATACTGGAAATGGTATGAATGGACGTACCATATTGGGTAGTGCTTTTGATAGAAGATGAATTTACACCTTTTGATGTTTGTTAAGACAATGCTCAGGTGTTATTTTCCAAAGTGCAGTGAAAAAGAACAATCAGGGTACACACCACTGGTTGTTACTCACAATTTTGACTTCACTTTTAGTTTTAGTCCAAAGTACTCAATGGTCTTTGTTCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +##$%%''78:<8G0?%,064.(0*+.*.,1&?KI@B)9**7<>>?:0;5678.(.$792:(.,*//+.+,BB=<<<>BEKCHEAFBF>=I=FD=955$('*''-0/2.<=:;KLBD,C<;79=;BC>?=?@;=H?88>A@F@F@B?;8:83-1=?9>5/*+&#$(%')($$%)&$$%&*-/'<=ECF;:)#(@@CCAE;?D9896CBN@:66-%%,.0@=:=>6:98JL@(%-*2/++'&6;AA?@?:0>6C?>@<@?HBACEC?GBD:9;*-;B=CF@BAE9;458769;=?DC-1BB5/=.+)+7--=7.'/8AADD>.0(3688$973+55?4<==:966<.?IHBG?EGH@9BDEQ:07,,4%%%%76AD=AB>:==A>>@:C7/5-=BAB=@FDCAB:&'/2017037754/++''% +@SRR11410539.432634 432634/1 +CATTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGCAGCATCTACAGCAAAAGCACAGAAAGATAATACAGTTGAATTGGCAGGCACTTCTGTTGCATTACCAGCTTGTAGACGTACTGTGGCAGCCTAAACTACCAAGTACCATACCTCTATTTAATTTTGTTCCAATCCTTTAATAAAGTATAAATACTTCACTTTAGGACCTTTAGGTGTGTCTTGTAACAAACCTACAAGGTGGTTCCAGTTCAACATAGATAGTACCAGTTCCATCACTCTTAGGGAATCTAGCCCATTTCAAATCCTGTAAATCCGGATAACAGTGCAAGTACAAACCTACCTCCCTTTGTTGTGTTGTAGTAAGCTAACGCATTGTCATCAGTGCAAGCAGTTTGTGTAGTACCGGCAGCGCAAGACATCTGTCGTAAGGTGCTGTCGATTCCGTTGACCCCAGCAGTCGTCTCTTTAACAACAACAACTACGTAAC ++ +%$,3/:@:?9=/-%;<=:(2.''*9:A::2BNKILGA>@=CC@@>'%:>A@23:>;=AFEDABAEA=:4604B><<>;?@?>==3,5?;F@;GE/8DA>-(?59;888:220++BBD?EGEA<:H?D@@?>@8;2;=>;B?AB<6@A<=;08>A><:,9680(%&$*+,.G3?<>7;??>A=7<7.(*&-/.-27'3@:>@++>BD@CI?F:;;@>9;>5-3@C6@=A8240847,()(/6756AB6:<=?><5;3/'()%+.-2)+((*69>8>>;=C>BFDHDB.7(:BC8:A>C?HFI?AA1?<>B89<>;858:$$98>CDCF=:DEA><=;BA>@A=73&+78:;>::?B=AB3<9@@,?=C:355008:78BDBD<>C=7;15H;:-2,.(9ABA/?>AAC>@?6)-.('*%045908:2;483766()9>F;:E>86<;?=4422-)&&&&&+&&*'),)-.1+441/-3$%%%%,+,./*/0322( +@SRR11410539.125624 125624/1 +CAATTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGAGTCCAACCAACAGAATCTATTGTTAGATTTCCTAATATTACAAACTTGTGCCCTTTTGGTGAAGATTTTTAACGCCACCAGATTTGCATCTGTTTGTGCGGAACAGGAAGAATCAGCAACTGTGTTGCTGATTATTCTGTCCTATATAATTCCGCATCATTTTCCCTTTTAATTGTTACTTTGGAGTGTCTCACCAATTAAATGATCTCTGCTTTACTAATGTCTGTAAGATTCGTTTGTAGTGGGAGTGATGAAGTCAGACAAATCGCTCAGGGCAAACTGGAAAGATTGCTGATTATAATTATAAATTACCAGATGATTTTACAGGCTGCGTTATAGCTTGGAATTCTAACAATCTTGATTCTAAGGTTGGTGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +1$%$'%))+&&#',&;;8/A?D?CA/,=::/>>@GIA?@@>;20.%%&5758498<9::?BC@@+=:1'&+'--;/0<@86@DDEC;A;398/.-/*87;@89DAB;?/66>=?799:+,322)&2;<4:8=0/)$9:FE?56@AC>538B:4+(,157688:B88;9=?=98;4AA=B;<;JB:;++32*%&$&3,-,'''&$'%&)'*+.&(&%')#%)+)&''2223=82375)**.264181.3&.30792$59C8$&%7%'('';;;==;8309..=;<=9;9=AGAD,?AFH?@'&/0679@E=A<2/**-8DE@A>?DC=;00B@8:HA1+++7;:?C9??E2(%(''((<=B;D;=:>?CFI@EADGED7=-*,0>A@68B6:7@7;BCB5:<::78:<@??>C===<9556>=87C>23+.+--+09:<?@50)+($)*,+/0+0.0(*,215*5--&&5:88E5615-.91@D?6:C:9@GHKD:5:5;?G@ED?E<2*42;=H@7&%%%'*9:04;::>1/8)))(.-;/@?<;87)+'$9/-&$-53&=;;@@?CC?):/8;=:<%%''&&&.2/0876688572,)('&+)--,.6689/,,1'$$&%*'+55736667:@;>>DFGDH=AA@<<>95>>KI>>/F@0*',1:@>C==BBCD@DA=?<30,&35:;B@B9>8:'+'*C)+8>>=EBAGGBAAAA>G5:(,/;96=:664;/A=A?53%48;=@@>?B7?-.-:9998@:?6<71:?=9=?DD<:54=5'4++$%+(%469:06B6?7365?;4(+:=D>@1>,?<;9C956;////857=F=@8:9:7<>;@@BA=>57527+48841%)(.,,$ +@SRR11410539.618617 618617/1 +TATTGTACTTCGTTCGAGGAAATTCGTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGTTAAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTGTAGAAAGGTTCAACACATGGTTGTTAAAGCTGCATTATTAGACAAATTCCCAGTTCTTCGACATTGGTAACCTAAAAGCTATTAAGTGTGTACCTCAAGCTGATGTAGAATGGAAGTTCTATGATGCACAGCCTTGTAGTGACAAAGCTTATAAAATAGAAAATTATTCTATTCTTATGCCACACATTCTGACAAATTCACGAGATGGTGTATTTTTATTTTGAATTGCAATGTCGATAGATATCCTGCTAATTCCATTGTTTGTAGGTTTGACACTAGAGTGCTATCTAACCTTAACTTGCCTGGTTGTGATGGTGGCAGTTTGGGGTGCTGTCGATTCCGTTTGTAGTCGTCGTTTAACCTTAGCAATACGTAACT ++ +&&02224,,1/7=4+'%*)(($0.&%&&&*'''*).8;<><7252@?A?:85AC:9<>@A9:>@:7<@GA92=@EJ9:C74A>:;@?>=*,77.&&,9=FHI66;HCE<>=C:8:45E<=C<9=2..*(047<<;@>;;:1966=7+5?C=366;8?AGABNO>>ADF:7BGCABKF9<>,5=75-$'88:9=8AA?C1&4.>>>A024))%%%672/;DC?HE78;CA/79;;=7988<@DG>;->=<*C<9<,2+)4<>>DIIKFDD9B376''$553?=@>@?,,+,.09?@<:<,96;@@>55('%(&&*2(*)'$'&&$$($,.-,$$%*12537774-5;<=:=95..?9/)B?G?B;>@@B8?@@?>@BBJL@HIK>A=D3BEEFBCB?6/*;222))%&-%%)'%9;<@B;==>;G6@6:<>;=@@FBF64/--2,23669:<99**#% +@SRR11410539.64134 64134/1 +GTTGTACTTCGTTTAAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTCTTTATAGCCACGGAACCTCCAAGAGCTAGCTTTGTTGTATAAACCCACAAATGTAAGTGAAAAAACCCTCTTTAAGAGTCATTTTCTTTTGTAACATTTTTAGTCTTAGGGTCGTACATATCACTAATAATGAGATCCCATTTATTAGCTGTATGTACAGTTGCACAATCACCAATCAAAGTTGAATCTGCATCAGAGACAAAGTCATTAAGATCTGAATCGACAGCAGCGTACCCGTAGGCAACCACTGTCTTAAAACAGCTGGCCTGTGGTGCAACTCCTTTATCAGAACCAACACCAAAATGTACACATAACTCTCATATTATAGGGTACAGCTAATGTTAATGTGTTTAAATATTGACACAGTTGAGTATATTTTGCGACAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACATACAGCAACTCCCCTTCTTT ++ +$%&032;<.6998+&'+@@A=8=?GE<:>;9-CI?>B;:@EG:EAC@@>??=<--*/652@9//C4AEKDCEFCC6;>,8;:?G<=BAC?=<6EOF?@HB;>87471<99.7517763@C9DG>89@3+,.+$%+-9:9;798;8841===,4+,6:<<=>@A<5?GF@?CE@BC88/,6:5?9@1$49;;=4@C6@@9:A<4<455;:9?E374ACEFFIGFF@<4C3@@66=?@ABC=>@=DFG=8<6,2,,,,+)''.C=A44;:54))*+'8975619013.+=9998.+-))%(8;22?G;8F:5DA?''>EEEEEBGH;@9J>B@37)@BFCAECEEA7:?GAJD=@;;?>@@79=<5$'%-,+/,+,$$"$$&('''%%%% +@SRR11410539.1015052 1015052/1 +GATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAGATCGACAGCACCTACAGAATAAACACCAGGTAAGAATGAGTAAACTGGTGTTAAACAGAGTACAGTGAATGACATGAGAATAGTAAAGTATTAAAGGCAACTACATGACTGTATTCACCAAAAGCTCTTCTAAACCTCATAAAATAGTAGGCAAGGCATGTTACTACGATGGCTACAATACTGCCAGCTACTATAGATGCTGATATGTCCAAAGCACCAATAGGTTGAATTAGTGGTGTAAACATATTAGTAAGTAAATTTACAGCATCTACACCACAGAAAAACTCCTGGTAAAGATCTGTAATAATCATTGTTAAGTACCCATCTACCACTAGTAGATACACAAACACCAACTTCTGATCTTCACAAGTGCCGTGCCTACAGTACTCAGAAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTT ++ +&$*%-%36;:A??A3/@;;3CDFHJG=A+A&CEA@G><:53)(4**/?CC2BH+78@>GJ;9<;A>HDCCD=1''&$+,688ADCC:>648/*+58@BH@=67//+4&&&*2+;698<@BA<<OQ?,5B:;:8:6@CCA>F??BFMFM<=7./1$-;<>>C5,+$%%67@CEEIBEEB=>8CA@6253A<;339*+).;;77CD?F9BBBA>=6879B<:FFKB12>8:=CHI@HG3*+133B>DFD@F>2;:=:HEAB<??5.7-6-8?AA=BDE<88CA96)).(+9:;=?4324=?>K>BA':A@>;>>;CF61364.0.,AEG=>>:76==DB787C:F9@B<9969;A=74+ +@SRR11410539.2047746 2047746/1 +CGATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACGGCACCCGACGAATGTCTTGTGCTGCCGGTACTACACAAACTGCTTGCACTGATGACAATGCGTTAGCTTACTACAACACAACAAAGGGAGAGTAGGTTTGTACTTGCACTGTTATCCGATTTACAGGATTTGAAATGGGCTAGATTCCTAAGAGTGATGGAACTGGTACTATCTATACAGAACTGGAACCACCTTGTAGGTTTGTTACAGACACACCTAAGGTCCTAAAGTGAAGTATTTATACTTGCATTAAAGGATTAAACAACCTAAATAGAGGTATGGTACTTGGTAGTTTAGCTGCGCTGGTACGTCTACAAGCTGGTAATGCAACAGAAGTGCCTGCCAATTCAACTGTATTATCTTTCTGTGCTTTTGCTGTAGATGCTGCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACTATAACCAATACAT ++ +%%&&&)'9<<7527>;<:966<>A>=@1;BD>EEE??@;;:'3D3=%%83A3>POJ:>:=??(&@DIDIF=))25-=F6//2@<:ML=9:>A>558?4;,ABA,,>?@81@==?A;@HDAB>DBA?;?I=FJ?DBE=F48>;;56494??IH@902A?B?:9,?**-8EH45:87.-24479,&&,,,%'&$(56&1;1;::><;@B=-=DFC<;$+$$0-966,''''(+*2,AAF?EAC;*;>>;>3702782(769(:=8;@?EB;<:5-)'**'@8>>FEB@987:@56;==?B@8887B@FFICGB=LDNL:DBDCAADH4@BAD3A;B@DB>CIG=@:;<656&(+3''%0&&&#%&% +@SRR11410539.2123302 2123302/1 +CACGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCATGGCTGCATCACGGTCAAATTCAGATTTAGCCACATTCAAAGACTATTCCAACTTTTTAGAACAACTTCAGAATCACCATTAGCAACAGCCTGCTCATAAGCTTCTTGAGCAGTAGCAAAAGCTGCATATGATGGAAGGGCTAAACTCTGAGGCTATAGCTTGTAAGGTTGCCCTGTTGTCCAGCATTTCTTCACAAAGCTTGTTTATGTCTACAGCACCCTGCATGGAAAGCAAAACAGAGAAAGTAATTTGAACCATTTTCAAAGGCTTCAGTAGTATCCTTTAGCTAAGAGAATGTCATTGTGTAACTGGACACATTGAGCCCTGAGTTAGATGATGATTCTACTCTGAGTTGTTGCAAACGAGAACAGAACTACTGATGTGCAGGTGTCGATTCCGTTTGTAGTCGTCTGTTTAACAACAATAATAT ++ +'#$$$$36:479)935BBD@B.-35/.7?@6@JFHKH<)):7218:C<@A45%'('2386*(''144;=8@=BJMEC<7A<@((1)''&6;@@>ADE>@@BBEBEH0??@01+&+%.7$)BDDMHFD1A*90878553=F;@H>A@AEDJGD=>=>??DGEA>8:'4,(%)(.0,=?=@A;?CEFKDBD?BB98)+:=A@=8::BAGF969AC:GGJELJJB63>??987777:947=<:A7930;>=ACEGDEA>7:(1=>877C.16.,&9(&(%%'&,-(&&%'+48;(6771-;END937763-1$$*)-+,7879;+,89H6.%6358'8./,,&7;>A?82%%'11=98*%#&&&)%&&.+*8:;>BB@;DJI>@B6688(&&'&'#&)%$$%*((48;=1,(&*')0&6:;>B4':?;:@:4777()420&''%$& +@SRR11410539.321039 321039/1 +CATTGTACTTCGTTCCGGTTACGTATTGCTAAGGTTAAACGAACTGACTACAAAACAGAATCGACGCTTTGGTGTTGTTGGAAAGTTCGAAGGTCTTAATGACAACCTTCTTGAAATACTCCAAAAAGAGAAGTGTATCAATATTGTTGGTGACTTTAAACTTAAATGAAGAATCCTTATTATTTGGCATCTTTCTGCTTCCACAAGTGCTTTTGTGGAAACTGTGAAAGGTTTTGGATTATAAAGCATTCAAACCAAATTATTGAATCACAATAGTAGGTGCAAAGTTACAAAAGGAAAAGCTAAAAAAGTTCTGCCTGGAATATTGGTGAACCAGAAATCAATACTGAGTCCTCTTTATGCATTGCATCAGAGGCTGCTCGTGTTGTACAGTCAATTTTCTCCTGCCTCTTGAAACTGCTCAAAATTCTGTGCGTGTTTTACCGAAGGCGCGCTAGGTCTTGTCGATTCCGTTTGTAGTCGTCTGTTTAACATAGCAATACGTAA ++ +(#%'-.*,,-*;B?(-'-88/*+3398,(6./0>><98+(($%$%,,5:/63477&$(48837//%$%%'/1>:C@;9++BC=81:)=A?+)%('&%%$.#$2,>>AGGJG2;3.1:;8:?@=:71---1''-%%,%%)(**/5;::;B>@EA=;.**9:8ADD<5566'+/--.%-*&*--1>@6/*+61,711.@AFB8=@DG?CAA?5-4,.&$)/0.5346>><=742,%$&)')%11,.2'-'+0+9>@:=;FA@DCBKDBB@F:>>6/''$%'%###$&%(%%&$'($'$$($('%$%)&-,87=@68:;:3,/..5527:3=?F=728,69<@:42+) +@SRR11410539.2159471 2159471/1 +GTGTACTTCGTTCAGTTACGTATTGCTAAAGGTTAACAGACGACTACAAACAGAATCGACGGCACAGCAAGGATCAGTGCCAAGCTCGTCGCCTAAGTCAAATGACTTTAGATCGGCGCCGTAACTATGGCCACCAGCTCCTTTATTACCGTTCTTACGAAGAGAAAGACCTTGCGGTAACCACTGGTATTTCGCCCACATGAGGGACAAGGACACCAAGTGTCTCACCACTACGACAAATACTGAATGCCTTCGAGTTCTGCTACCAGCTCAACCATAACATGACCGTGAGGTGCAGTTCGAGCATCCGAACGTTTGATGAACACATAGGGCTGTTCAAGTTGAGACAAAACGCCTTTTCAACTTCTACTAAGCCACAAGTGCCATCTTTAAGATGTTGACGATGCCTCTGATAAGACCTCCTCCACGGAGTCTCAAAGCCACGTACAGGCACGTCGCGAACCTGTAAAACAGGAAGGTCACCACTCGATTCCGTTGTAGTCGTCTGTTTAACCTTAACCATGCGTAAC ++ +%6-4377:65?=+&&/;65'2+*/6?@;;9<<>>BE?F::8/66=98:9?&,0)0%%%%&=E=2;7;DBB?-./ABA??FF@>:;=87@@AB>GCADE;<;=9=08@A@???B@<8%:344.//..7231715-**-17=?GFCFE@7543--%.,%&/((((###&.2&**8:<==@;:=:C<=;<3=14--%=C52?@89A9++7/17C>;=,A>?871('.8:800/24<.IBI?CABD4;329EDBD?-4@ACI?D?@77>?6<6,3;<<5))$5753AAF1+AIC;88IAC-->))1A@HHC@A?229C>;:2/8=@@=;E;@::58+%')(*35;8/.==<:701--/07;7561'($$$')%'-B4315=@FECABC2>?7;@<:$$13164B:BBA:;DC>9:16A>E8?9=8?9;.B=>(&88$2+:;6$$977=0-B:?99<=>>?8<>:-/$'$()'&%##%&$',>@GKG;=>@@0,0/0.&=?<6AA<75*,*,$%#)+''+('('% +@SRR11410539.1668473 1668473/1 +GCATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGGCTATTGATTATAAACACTACACCCTCTTTTAAGAAAGGAGCTAAATTGTTACATAAACCTATTGTTTGGCATGTTAACAATGCAACTAATAAAGCCACGTATAAACCAAATACCTGGTGTATACGTTGTCTTTGGGCACAAAACCAGTTGAAACATCAAATTCGTTTGATGTACTGAAGTCAGAGGACGCGCAGGGAATGGATAATCTTGCCTGCGAAGATCACAAACCAGTCTCTGAGAAGTAGTGAATCCTACCATACAGAAAGACGTTCTTGAGTGTAATGTGAAAACTACCGAGTTGTAGGAGACATTATGCTTAAACCAGCAAATAATAGTTTAAAAATTACAGAAAGAGGTTGGCCACACAGATCTAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +$%%$)<::>A:9N?=8;9;>7-.+,3%6,44,DGGCG357;77@?>8@98722,15:>:B=6;:;492*$&28BA?C9GLRB::+55,03.@BC<6;5&+BA:=@E?@55>355.463%,-,58?C@BC>;745<>?BBB57=BBEACA@D?=;=?>9+--345:;A:75/9/5;:8;;=8CBDA@C?@UKGA@JDF;>6;3,'3;5=.6;C>?;=87CD03:667>CBB448EBBDF==?CAAG<7?AC71)?4938>=2***=-,00''$$%13,17541157=AH>B=MMBCMF@/.0*00.:8$539>>=<=A@A?B:<=>:>>87>@<<;CA;AEGPH78=;<<=ABA=>=?=78?ACCGC>.'#& +@SRR11410539.814121 814121/1 +CGAATCGGTGTGCTCGTTCCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAGATCGACAGCACCTAGGTCTTCCTTGCCATAGGTAATTGAGAGCGGTGAACCAAGACGCAGTATTATTGGGTAAACCTTGGGGCCGACGTTGTTTTGATCGCGCCCCGTTCTCCATTCTGGTTATTTGCCAGTTGAATCTGAGGGTCCGCAAACGTAATGCAGGGTGCATTTCGCTGATTTTGAAGTCCATTATCCAGACATTTAGTTTGTTCGTTTAGATGAAATCTAAAAACAACACGAACGTCATGATACTCTAAAGTCTTCATAGAACGAACAACGCACTACAAGACACCGCAATTTAGGTTCCTGGCAATTAATTGTAAAGAGGTAAACAGGAAACTGTATAATTACCGATATCGATGTACTGAATGGGTGATTTAGAACCAGCCTCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTATTTAACCTTAGCAATACGCCAAC ++ +)*&%%&#&,,/$$'&##,$+&-015464..8,672239?=54.,7.:D@B<;6C9:+)((0%;8AD@<>5E@GF826@>DC:9=ADCID2)##$&%)%&-.$+59,.2;//(6459>=2.6$$$%'#%)37HAFIE2=1114A7ABCED9D<9C@A<87BC8:::0?2623*;&&-%(/214119;<@,'749HDHDHNNJFC?@2353&&5,1/@AFBA9>:;A;D@=@GD?A?E>E=A>7?:DE8.%(779=:424*&569===A@B<<3340%+++69739==E@((/<@@<5652350<=<,%#$'#9797=:61@MG68B@DGCAML?@@E?=CE0('./5<@?6*++9=9A<9??HCDDECEE@@F<6DBBCA>:HCC?FC7B?>>?;==A>?<5;86.)9:*$+,,11%)$&%$$&&##&&$%'(& +@SRR11410539.1096916 1096916/1 +CAAGCGCTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACCCGCAAGCAAGTCGACACAGCACCACCTTTTGAAGAAGCTGCACGCTGTGCGCCTTTGTTGAAAATAAAAATGTATCCTAAAAAGTTGCGTAGTGATGTGCTATTACCTCTTACGCAATATAATAGATATAAGCTCTTTATAATAAGTACAAGTATTTTAGTGGAGCAATGGATACAACTACTTCACAGAGAAGCTGCTTGTTGTCATCTCGCAAAACTCTCAATGACTTCAGTAACTCAGGTTCTGATGTTCTTTACCAACCACCACAAACCTCTATCACCTCAGCTGTTTTGCAGAGTGGTTTTTAAGAAATGGCATTCCCATCTGGTAAAGTTGAGGTTGTATGGTACAAGTAACTTGTGGTACAACTACACTTAACGGTCTTTGGCTTGATGACGTAGTTTACTGTCCGGTACTGTCGATTCAATTTGTAGTCGTCCTGTTTAATATAGCAATACAGCCAAC ++ +5**##$)+/+6;2/#''-(*079:<76*3&ELG@A8-'.'311(&'$(-.,2+,+692++)-467:77&%&%//.00<;?5(..'#$)*/.*(&$$%%(-31--''&%$$'+(6<:<=:%&)6=?<428B?-.$''+88>B-+,,-.*,077<344:7,0?@>DD>B8@59,#&$&-831'*>?@=>1:9<000,-%&'$&070/7;,:>;8359,?BC>A0,;19%%89,*133*@==897@DC@;>@:;9AB>7BB45;9-/&5=EGBA?AB;<8>98:45;3ACFGCI@>2@-.>D>@KJJ>9((*45?:/5;8=@4=@@=BC69??A=5=/-%0?HK=92'&**),,-0=..((*2@AEBH@D@9A<>5&&*BEHBB<>DEB49>@>65;;9+-.0;04?;028..9$((%)*4:92131+&'*2B2::<>>9$$'/.57,+)$$'%%&((+&&$%%%)*% +@SRR11410539.1682158 1682158/1 +CGGTAGCCTTCGTTCCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGCCACAGTACGTCTACAAGCTGGTAATGCAACAGAAGTGCCCTGCCAATTCAACTGTATTATCTTTCTGTGCTTTTGCTGTAGATGCTGCTAAAGCTTACAAAGATTATCTAGCTAGTGAGACTTGCCAATCACTAATTGTGTTAAGATGTTGTGTACACACACTGGTACTAGTCAGGCAATAACAGTTACACCGGAAGCCAATATGGATCAAGAAGAATCCTTTGGTGGTGCATATTGTTATCATACCGTTGCCACATAGATCATCCAAATCCTAAAGGATTTTGTGACTTAAAGGTAAGTATGTACAAATACCTACAACATTGCTAATGACCCATAATAGGTTTTACACTTAAAAACACAGTCTGTACCGTCTGCGGTATGTGGAAAGGTTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTGCCTTAGCAATGCGTAACTTA ++ +'$''($$$'+25=>'+&,?A;:6:69?16=/01=ACGKD=89<8A;22@A6A?@A=>DC>A99;:8?8DG>;:@@<9AGEC9B55?CAEBCHD=?NJHA75A?787;>@DC@DH@60:9),&03&%&#%*'%&554;DA769552?=AB%&:??:BC547==99.21?<>:4'&-+&53744?=6661240238A=D9>17=EC5=<>CDA=@?7;./4$$2AD9:DD::A>>AA>AA:?2+9777335'&,((*''%$$%*)),)7??>A6+/+%%)4574+56/3,589566432::A;>CCFE;:=;?-1B/)(0=;C@@DADD;;7?>?HLC=%%84><<;8=DB7-&%6??HAHBEA?A?>?7;A?;>GCB948>BHDC><::<0=5,8>>>FE:FEB9A23)34A9A(/CBD>5@85<@>9?7096-&##%$$92.2=<7C8?:40//-*)/3;<-+1FD=@B-/?<;::7;??@HDA@=@@?EB;===IJBC52-6;;BD()02278:5(*./8-BDD33B>A;=86<>AEEH=?9BC@417:**AADC<==@BA;:5;KIE87)'&'669@>?@E.672AE;4+%(1-*--14/,7<;/9D>B?DDBG>HJ78=>A=>JKD@GD;3+*$(,*/>7<@26DG75.:;FH>:A8:A?A:9683,($&'')(00,/*&%%&++*5;66:=A=CA@$('09?<:>B@>>G>?;=;;;56>=65+*'#%& +@SRR11410539.1305186 1305186/1 +TATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCTGACAACTATCGGTAATAAAGGAGCTGGTGGCCATAGTTACAGCGCCGATCTAAAGTCATTTGACTTAGGCGACAACGGCACTGATCCTTATGAAGATTTTCAAGAAAACTGGAACACTAAACATAGCAGTGGTGTTACCCGTGAACTCATGCGTGAGCTTAACGGAGGGGCATACACTCGCTATGTCGTGCTTCTGTGGCCCTGATGGCTACCACTGCTTGAGTGCATTAAGACGCCTAGCACGTGCTGGTAAAAACTTCATGCACTTTGTCCGGAACTAACTGGACTTTATTGACACTAAGAGGGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCTTGATGCACACGGAACGTTCTGAAAGAGCTATGGTGCAGGTATACCTTAGGTGCTGTCGATTCGTTTGTATCGTCTGTTTAACCTTAGCAATACGTAAC ++ +$$3355;,8&788=;7:./2GIIHKA92441**),)*5609@88$0&+##"#'-A0CH:-27.0)2&'')-86:@DHCFE445B?B2),;==:3951;A46?%75+56?:@E@B>969/9<8=:79<89;:>D@<**8=430-$%%%.7@C=7>AC73888833:0')/.-2((//4566879,,*07./%%%/02228EEIFMMMMGG@>@B-6@@5C=89BGA@FEDI413987CED?A@IJ8H<550/#$$$.-4@15=CEB@.>298>6)>962,*+-90*#%$$$$%79:<&A@?<+2<8:://17:?BD@A@>A95?8EEEECDDBIHAA@AB>?;22.*& +@SRR11410539.2013324 2013324/1 +CAGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGCCTCATAAAACTCAGGTTCCCAATACCTTGAAGTGTTATCATTAAGTAAGCATAACAGAATACATGTCTAACATGTGTCCTGTTAACTCATCATGTAGCTTTCTTATGTATTGTAAGTACAAATGAAAGACATCAACATACTCCTGATTAGGATGTTTAGTAAGTGGGTAAGCATCTATAGCTAAAGACACGAACCGTTCAATCATAAGTGTACCATCTGTTTTTACGATATCATCTACAAAACAGCCGGCCCCTAGGATTCTTGATGGATCTGGGTAAGGAAGGTACACATAATCATCACCCTGTTTAACTAGCATTGTATGTTGAGAGCAAAGTCATGAGGTCCTTTAGTAGGTCAGTCTCAGTCCAACATTTGCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAATACGTAAC ++ +()$%)1-<>CC?L(0%<9;8<>DCBC::9()*>JCADA8))0)1012:9<=1?8;05/6:GFGB<=:7/01*-.=:@707.AB;=JC90087559,(1=8@B@B?661$%-6<><<8?<@AK=@BDEA=@<6=;B>6@<;9=223<@:;:<<@>74:@=8-A+9IFGAADD?EHHFIEA;<0.-9<=<77<@:5C<76:%&:=?=298::FEM=9@C@C=57FB>=688B:?FC886BD@CBD?C==D@CA=ACEHE;:>><;8-?7941,-.@:>C?8,,&/%$**0&339,459==FI:6;=BFB@A4897==4$133:867>79=BC64/0051*7259;8754..410/(.094-2024?CBB?:>9:E@<886855<@>B8;6@9B>>95<2%85=+=?AB,0-.1'',&'&),,./:+9:=899<;C.(09ACHGG><(+()@@?>>CD3;((%&,-212048.738033&(010')0)(.8===F:;ADC=<8/-)-:@8-/3:@A=:&8;4E*=45)4/.5:99263;/5333;??+.6*2<=/./'(%%*%%#&&$%('-()''# +@SRR11410539.1147191 1147191/1 +CAAAGTACTTCGTTCAGTTACGGCCCAACACTTCATATACAAGGTTAAGTCATTAGAGTTGTGGTAAATCGATTGAGAAACCACCTGTCTCCATTTATAACAGCAGCATTGCAACCAAGCTAAAACATTAACTGTAATAGTTGTGTCCGTACCAGCTGCTTGTGTGCTGTTTGCCTGTCAACAAAGGTCCATAAAAAGTTGCAACTAAGTCTGTGCCAGCATGAACTCCAGTTGGTAATTCCATATGGTGCATGTAACAAAAGAAGACACAGTCATAATCTATGTTAAAACCAACACTACTGAACTGATGATAAGGAATGAACCCTTAATAGTGAAATTGGGCCTCATAGCACATTGGTAAACACCAGACAGGTGAACAATGTAACAAATAACACTGAAAAAGTCTGTCCTGGTTGAATGCAGGTAAGGTGCTGTCGATTCGGTTTGTAGTCGTCTGTTAACCTTAGCAATACGTAAC ++ +4#$$$''.058:L<;77>5+3./...(*-:9;77&#,*,<79;3CFCC:<@::0:'(5(,>A>A>4468A?>G<87)132(-:=<=:89@=@?@?74=762%*,&*+*,5%44377017=:@A8.:6347.+:<>>>82@@C/5:00.&-1;:B6<>5..4-&$(013276@9>:D>8C--7;<%)+))-+3?@A3359=07&&$%---)/.';<>?@C8/+),)79*>A9;9;9<>>>;99;<9;=D99C.-0&'%#&&*9*.8C>:AE?C6@CBDB@@DEB=?95?316*$%%&%)...77<=:<;00' +@SRR11410539.1083446 1083446/1 +CATTGTACTTCGTTCAGTTACGTATTGCTGGAGTTAAACAGACGACTACAAACAGAATCGACAGCACCTGTTGAGAGCAAAATTCATGAGGTCCTTTAGTAAGGTCAGTCTCAGTCCAACATTTTGCTTCAGACATAAAAAAACATTGTTTTGATAATAAAGACGACTTAAAGTTCTTTATACTATACCACTAGACGAGATGCACTTAAGTGCTATTGAAACACACAACAGCATCGTCCAGAGAGAGTATCATCATTGAGAAATGTTTACGCAAATATGCGTAAAACTCATTCACAAAGTCTGTGTCAACATCTCTATTTCTATAGAGACACTCATAAAGTCTGTGTTGTAAATTGCGGACATACTTATCGGCAATTTGTTACCATCAGTAGATAAAGTGCATTAACATTGGCCGTGACAGCTTGACAAATGTTAAAAACACTATTAGCATAAGCAGTTGTGGCATCTCTGATGAAGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +(&')'((674::B/<59FD<:684?B')/$%$9NEAEE945?BHI?CB>==6((%.1:=CECCAADB>I7CA>9EHF4252>CCF?FDA@224'+3,,(&,$(&@GFHH46EE9,%%'&%&#$%.*2003.&)==D@@<,,0@B;E?>>8>>34=<>@@FD??7E4CC<@<%%:@(((2168::58DCB88413+(5411LDDA::E@A@@>864/012=@:C<@B6AFAC1;>7C@>@;=3;;:6;;.=>C>:FI64152/''',,?9?'-6$'$*<,80%033,>/0572CADHB1IGJIHG>>LGKG>@CE?BBA*,&'(*439.042/;>GJKA-'1//514?48::34-/./<@5*8/7?>C,8,=:1;.,020-/577=@@B9;7JHH@CA8.<98.7=47876:99<97@;:66FDA(5% +@SRR11410539.74585 74585/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCATCCAGATTCTGCCACTCTTGTTAGTGACATTGACATCACTTTCTTAAAGAAAGATGCTCCATATATAGTGGGTGATGTTGTTCAAGAGGGTGTTTAACTGCTGTGGTTATACCTACTAAAAGGCTGGTGGCACTACTGAAATGCTAGCGAAAGCTTTGAGAAAAGTGCCAACGAACAATTATATAACCACTTACCCGGGTCAGGGTTTAAATGGTTACACACACTGTAGAGGAGGCAAAGACAGTGCTTAAAAAGTGTAAAAGTGCCGCACACATTCTACCATCTATTATCTCTAATGAGGAAGCAAGAAATTCTTGGAACTGTTTCTTGGAATTTGCGAAGAAATGCTTGCACATGCAGAAGAAACACGCAAATTAATGCCTGTCTGTGTGGAAACTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACCTCTATCTTTTCA ++ +-(()7::69<:>G;66;HEH??HJBH;;=568FIGHLE;666@<>;8==:;94277?>??C=8AEE=>F?<%%?79798:;C99,++';=;3,:C<37>@>=9(>:<8C;<A?ABADA96GO=%&ACDIIFE><<:;:==;<;<=A@;;@?;?A=26<6DCEAC=A?BDB>=?65:2<'>;=:=4121,73:>B5FG;?D<:@;89;8FJL947377?A:-)>1,,'())0;;@?@<;=?.,=/B<;=:9;:CFJDJF6&@79?DE4DIG5LB??<>;//>ACEEAIEMPJENKOA:23&-+01..))0?ACAE>><++3*2B=:@=;:><=>AB>@:3<?;<%65=3;?@?<@:>ABEB3=;ECE6:A?<>==>>=FFCAA.3.0((&$&&(&+++,'$$& +@SRR11410539.909503 909503/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGTTGAACCTTTCTACAAGCCGCATTAATCTTCCAGTTCATCACCAATTATAGGATATTCAATAGTCCAGTCAACACGGCAACAAAGCACTCGTGGACAATGGACACCCTAGTCTTGGTGCATCACAACTAGCTACATGTGCATTACCATGGACTTGACAATACAGATCATGGTGCTTTGTAGGTTACCTGTAAAACCCCATTGTTGAACATCAATCATAAGTTATAGACGTAATCAAATCCAATAAGAATGATGCCAACAGGCATAAGTGTCTGAAGCAGTGGAAAAGCATGTGGCGTCTATCACATAGACAACAGGTGCGCGCTCAGGTCCTATTTTCACAAAATACTTCATAGATGTCAACTCAAAGCCATGTGCCAGGTGCTGTCGATTCCGTTTGTAGTCATTCTGTTTAACCTTAGCAATATG ++ +#%)+(*(--0*6@9/&)799:4=9;A214+,2@?9.1/4./0.3/3<48=>:4+-0;:;AF=487A@?IEFC?AB;@;>1:*)),/*;<8>989==4-EB&):@;?B=8E;CBDEDD55A>;8B?@?;;&'&,5AEBE2(>:;84,/-(/<8:982,(###',%&9.7=>BGE==?AG:<69E<9=EAD;;>E@CFF?@A*+9?BBGH5C=0/=6;/7)(5349?E;<9>?C@>=71...00A::9%&:AIADFEEIF@@>@<@B;3((,ED=>.-';:=7><+,32-&;;/456.41/:<:95=9;DD:6:ABCLAB;>>5=<@=BC?;E:;+2?GIEGC@B>CFAE?EA?4.%$*.%')&*,-(-&++&,385>**>;BFBCFEBE8?9<4<:<>EAHGEBBBEADBDB:A<<97:<>B?F89CBAB0;'-./'4=<6732$(.6127A?<64500.*((+%&&&&(%&%%(-%//((-(0&'-*67AC><38;>A;7801()0+/D=F<2;+1%)-**0989.#%1777117++/+9;=>*),*,)0/0.3+%963+%&(%&'(&%)$+'&%&%&+'('/%&)+226.>293@4547;?BA<:>;EAAD==A??@C@4368::=9104;.18%63/:>>802+&%%$$)&$%%%'5727#*-..-/66722,(*)*$$(%+0&200-+*/-*5*6,8(&&&(,-,.,,4)*3'*&&+,+&&,&$-/046,-=@45C=:EGLED2+;?0*241%&%)& +@SRR11410539.65839 65839/1 +CATTGTACTTCGTTCGATTACGTATTGCTAAGGTTAAACAGACGACTACAAACCCGAAATCGACAGCACCTACCTGAAAGTCAACGAGATGGAAACATCTGTTGTCACTTACTGTACAAGCAAAGCAATATTGTCACTGCTACTGGAAGATGGTCTGTGTTTAATTTATAGTTGCCAATCCTGTAGCGACTGTATGCCAGCAAAGCCTGATCACCTGCTACACGCTGCGAAGCTCCCAATTTGTAATAAGAAAGCGTTCGTGATGTAGCAACGGTAGTTTCTTTAGGCAGGTCCTTGATGTCACAGCGTCTAGATAGTGTCCAGCAATACGAAGATGTCCACGAGAAGGATCACAGCTCCGATTACGAGTTCACTTTCTAGAAGCGGTCTGGTCAGAATAGTGCCGTAGGTGGCACGTTGAGAAGAATATTTGGTTTCTGGATTGAATGACCACATGGAACGCTGTGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACATACCAGCAATACGTAACA ++ +'%'(&&$))).7<-,'$/3.14C?EH7B79:/?LHCGGCCCDD>>;8,1++(%)%$,30,,(3)%)5,3%)%99@??C><:;():;>7D>&'*/9>8;>>658489((((-120544>>87766194.%%%)5=?;8;13%*$2.&')&1(=8596575;@>9B>=@=:6%+57>9*4/1.,)*/+*)*(&(''*$''%'''&%%%)33988=220+)*-)/%%,4444;;%'%+:,2;@?D/@:/A5*;EA<=GGEG70&==23A&03&%4:=789&'/*,&5:33:5@FFG>:D@:6<:-'A(&.)-)9@;((=4:3240/24428>;3,,;55-.%./,:@:@>51DDD(<84;;674387<@<E?;?H>6434-,22((><5'*-3@7,.3,==?8?@CD;;,;-;8=@<**--*/*0042>539?>?:6>BDA?9=;>?B@B?@BA1-*/)9=8A;55,'(+,-&++,>C;=@>44%*1&&$(1-225//36..-'&**)'4130,5:AH>>>)&EEC<9C;:8GF;B?7=<:9689;=A<:,5'487::F95:/B778>>A7;=*000BC6@>@?><@BCC<6?1@=BC74;7:611>?@//>((1.1589834>B@D:=C@84A@BDCEJFC67:@AF?I5>BCA5<29:;?KD@E=.)AC=<@@@GDDCHHDD7?38*3*022=8@>>88>;>=/-41<@,($,+.+0//@EFH;(>9635;=4519:AB=C:8973:8AECGLJD17.-.=@B?>>:=<6/*,%#(&#&#+%'(,7<;1203001>=@<65'61:*<97-0/<<34/21978=@1B*44@?=?@AD='%*$)-,21)''AA?;455;:C<;86;9ECFAGAE@H=54-45.&%.-2'/+57756;=88<91+4&)%33077-&,+-1068:;9=;00103+4%:7C:CHDSMGAD/>=9=?GDA?A:/<;>BD0/?:<672$+-$%1AC<549::=78;>?=3:95.*688'9>752++77BE=;2/66/'*'(///'',#$$%$6@99;-6A38823/.:76'**48<;9===9414359861)(#%'(0-;B=@82+)=/AB>>9<>B5(''':?@):(3&%2,,<>?CBAB86;(+$;>:9EC=ABA?>9<;975*+462758;9>=>;44%($'+%*7:@FB;9++$( +@SRR11410539.1178449 1178449/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGTAATTGAGCAGGGTCGCCAATGTACACATAGTGTAGCACGTAATCTGGCATTGACAACACTCAAATCATAATTTGTGGCCATTGAAATTTCATCAAAGACAACTATATCTGCTGTCGTCTCAGGTAGTACGTTACAGTACAAAGACATGCTGTTCAATGTTAGATTCACTTTGAATTTATCAAAACACTCTACACGAGCACGTGCAGGTATGAATTCTACATTTATCTATAGGCAAATATTTTAATGCCTTCTCACATAGTGCATCAACAGCGGCATGAGAGCAAGCTGTATACACTATGCAGCCCGAGCAGAAGGGTAGTAGAGAAAGCTAGGCCAATAGCAAAATGACTCTTACCAGTACCAGGTGGTCCCTGGAGTGTAGAATAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTAACCTTATGTCATATATT ++ +&78;8600.6=I==8=B5,=8A=B>52-%%&9>=ADB?9;??BE@FCC9<3A=>6=?==E>:AAA@CGAEIHIE=8:16/7<8444415992.//9:4/5?6?@EDEB@>?<496(..*+2955;;@=CCD@A@@;224BC4<9?:?8<=)3+10(&$))5-6;6783=8=9:&)@><--97:A,)45-.56$$8=13//885&&'66>=<>;<;C:<713034$<&74819778?8,&,&.2),<>:GLID<=0)5122448>7:<>D>>?DAB?9=E>G>AD?76A33-,)52:D9<>9-459/11859578;979<66(%%+&)()'1)%*&++%'.)4)*'#'%'(,=:**9;>A8/,--8:7=89233+14654<689@8<=>>@;*+''*<@FD;>9=>;@AA8679;83$$#%%'%&&&0* +@SRR11410539.1092856 1092856/1 +CGACGCTTCGTTCGGTTACGTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACTTCATAGCCACAAGGTTAAAGTCATTAAGAGTTGTGGTAAAAATCGATTGAGAAACCACCTGTCTCCATTTATAACAGCAGCGTACAACCCAAGCCTAACAGTAACTGTAATAGTTGTGTCCGTACCAGCTGCTTGTGCTCTGTTGCCTGTCAACAAAGGTCCATAAAAGTTACCTTCTAAGTCTGTGCCAGCATGAACTCAGTTAGTATTCCATATGGTGCATGTAACAAAAGAGACACAGTCATAATCTATGTTAAAACCAACACTACCATGAACCATTAAGGAATGAACCCTTAATAGTGAAATTGGGCCTCATAGCACATTGGTAAACACCAGATGGTGAACCATTGTAACAAGCTAACACTGAAAAAGTCTGTCCTGGTTGAATGCGAACAAGGTGCTGTCGATTCCGTTTGTAGTCATCTGTTGCCACTAGCAATACATATAAC ++ +$$#%$%)*/6:/:%*9;6+((('*69.8,FHB=AE6;64/*)%'((,.001685/44:86;<>A@GBAA@@5:5233??:;7=>@>@244.%-8<>AF?:?CBB620/687=?1AA@::;B4867<@@<=<85;1-2++*..+*'((*++*('$&%+$1237:98550/67;'0855900,<72=<>://10/'%3,149:+456/--*).==)2?78;7(>>135HHB;9;1,(''*7339CABFE5B;??0'0/503:>>?A?>B@B:4$$)))***'%'78??D40?7=;F=@;>DHOB;:80-55.-.,.<=>F>>888DC:BEIE77@HB88>;=1;:533,--328?@?@8))+*+$,&&(.24-/+.**69:;A;<;BBBBA?B=:=9=>DQK?6.56B?77=::=BB?DA64;4578>>+@B=;9238>@B=+.;??B:36674(-96450##'&$+'&'+,)(/-**2--( +@SRR11410539.1753754 1753754/1 +GATGTGCCCCCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTAAACAGAATCAACAGCACCTTGCCAGAGATGTCACCTAAATCAGCATCTGGTGATGTATGATTATTAAAATATTTATCTAACTCCTCCTTGAATGAATTAATTCAGGTTGTAAAGGATCATAAACTGTGTTGTGGCTTAATTCCTATTACAACATCCACAGTTACCAATTCTAAATGTGTTGTCTGCGTATGTGATTTGGTTCATAAAATTCACTTTTTTGTGACCTGCAAACAGTGCGCATTTGAAACAAGACACCTTCACGAGAAAGTGTGCTTTCATCATATGACAAATGGCAGGAGCAGTTGTGAGTTCTTTTCTTTGTGGGGACATAGTCATGCAAGAAGACTACACCATGAGGTGCTGACTGGGGAAGGACATAAGATGATAAGCCCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAGCCTTAGCAATGCAGTAAGC ++ +##.$%#%%''05@,71657)40)&/2(5878+5,2)*/3%%1/3-++464/1));;=,*17*5*--+-(+05694<..5;/-&5%,4-,3$5??GE=?DFCFB:98328,$(*2464,,01=75:3)**72888>89626+)$$$&/2.--'0005(%.1)*><69==CF?>@4648;'+')''(465935.8-1+33229-.5()%'./+$0.0..('()/.,4,8<,662&(,*(%%,3+38(,0317()*,)()--&$%%%$$$#''%'((*122)+,%;'$()--/,'%*(.%&0:>A4=2/5&533+,1(,?:=:8991,&%'&&%57>EFIIF=?953971/-=B?2$$-%,3:EDIB8::6.('*67/.&&(*41-,*-./10+65**17;;<;;;)&88;?+6$,.-+**,./*).%%%((*( +@SRR11410539.1246576 1246576/1 +CAGTGTACTTCGTTCAGTTACGTATTACTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTCACAACTTGCGTGTGGAGGTTAATGTTGTCTACTGTTGTAAACACCTTAATAGTCCTCGCTTCTCTCAAAGAAGTGTCTTAAGGTGTCAAGGAAGAGTAACTTCACCATCTAGGTGGAATGTGGTAGGATTACTAGTGTAATATACACTTTTATCACCTCTCTTAAGAAATTCTATACCTAGTTATTGTAGATTGTCCAGAATAGGACCAATCTTTATAGGAATCCAGCAAGTGAGATGGTTTCAATAAAATGTTCTTCAGGTGTTTTAGAAGAGAAGAAGTAAGATAACCATTATACGCTGTAACAGCATCAGGTGAAGAAACAGAAACTGTAGCTGGCACTGAAGATCTCATATACCGAGCAGCTTCTTCCAAATTAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACTTT ++ +(%$'*64?AC@AA1@9=BCC85>?<1&9:0031<D=BD8;JLHAD8:EC7?D>8AD:=>6567,,>=@?=.015979<1?+47==9)0'==''++6A<;==<;;%&=1-1/.,-0//44;887=A43/3?=@>239;240.,-1?BEGABD@D;9<89<@@BEC60073222216:;><;A7GE@7:6?@A67757;<12B@>?>DC@EAD>>D4:.5-'1*6--/.C=><>>*8ACADG.*<649C8:?=48<>34;F<@BE66B?<29@''>?<+4311'/9AC>A<:9830+178;:>@(+35>><4;*0%'/5;>?CF@9;=C@7AD?=A@?@>BBB;@A<><=E36;<>?;10(2''++ +@SRR11410539.1896966 1896966/1 +AGTGTACTTCGTTCGTGCGTATTGCTAAGGTTAACTGCAGACGACTACAAACGGAATCGACAGCACCTCTCATCTTTAAGATGTTGACGTGCCTCTGATAAGACCTCCTCCACGGAGTCTCCAAAGCCACGTACGAGCACGTCGCGAACCTGTAAAACAGGCAAACTGGGAGTTGGACGATATCATTTTTCTCGTTGAAACCAGGGACAAGGCTCTCCATCTTACCTTTCGGTCACACGGACAAAACCTAGATGTGCTGATGATCGGCTGCAACACGGACGAAACCGTAAGCAGCCTGCAGAGAAGATAGACGAGTTACTCGTGTCCTGTCAGCGACGGTAATTAGTTATTAATTATACTGCGTGAAGGTGCACCTTCCTTTAAGCATGCAGCCAGTGACAATACAGATTTTAAAGTTTCGTTTAGAGAACAGATACAGAGATCGAAAGTTGGTTGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTGGCAATACGTA ++ +#'#$&$***9;>+,$*&.,623:;@:89);><:,$)#'%,%497:>;9..013<;9:;073/99<:==>+):*;55)&B<6/*1.7,,7C@C<;C;?@?=;?:4:?AD=/'13679+//-,)$*'.;>=5,,'%&%$-//,5309:F??6=>>8087/C<@8ADIKD8>DE>E40&<15+EBG@CFFB8?A6%%2'7A;AB:=BC8,+19A??===/<;5@A>21.-'&('0789=;;449AD><;<:B?++01)/*/'.>EI39114,+$'&(864,%%"%%%+((*(*+-+&&-A>=ID55311168551(''-*,(3+::;C;?KD:=BC;><:6-A/:;:7==9;<8<@EDIBABB:6<<@BBEB4+,,0--(//+*'&(#%$ +@SRR11410539.209013 209013/1 +CGGTGTACTTCGTTCCGGTTACGTATTGCTAAGGTTAAACAGACAGCTACAAACGGATCGACAGCATAGGCTCTGTTGGTGGGAATGTTTTGTATGCGTCAATATGCTTATTCAACAAATGACTGATCTTTGAAATTGGATCTTTGTCATCCAATTTGATGGCACCTGTGTAGGTCAACCGTTCCCGAAGGTGTGACTTCCATGCCAATGCCTTGACATTCCGAAGAACGCTACAGGCGCTGGGGGCAAATTGTACAATTTGCGGTAATGTTTGTAATCAGTTCCTTGTCTGATTAGTTCCTGGTCCCAAAATTTCCGCCCGGGTTTGTTCTGGACCACGTCTGCCGAAAGCTTGTGTTACATTGTATGCTTTGGTGGCAGTACGTTTTGCCGAAGACTTCTTAGAAGCCTCAGCGGCAGATTTCTTAGTGACAGTTTGGCCTTGTTGTTGTTGGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACTT ++ +,$&&'*)4541005$&$*$653+/((*/:A45+=G>13)'$)%)%$%&#$#$$/%).$$//((%*'.,8=36@47:@F9:?=HB@AAB@>>=@::<=<<=BE@AB5''445*101((12;>@?44*))*08==67///,'(&//D)))FEC=@788AB?B7)9+'9>9A3442'25'-8;::.5B'596CPQBH:/*%%$$'$##$)63;<=>,1<6,-,-''12(())12357*,/)*.''$+401,3#%+->4+81)=C;;C?:?@D>O5-39=;;H==99@>@A9DADC)+$$%(&,>CDB@<8=?>CC?$,815/->>=CBJGJ:4521+.1%(6:;4564927=:63-(($)'-%%%&-$$)%07AE1?:C=;1*30:>??0F?C?A22.-.-*79;;;8''+ +@SRR11410539.393760 393760/1 +GGTAGCGTTCCAGTTACGTATTGCTAAGGTTAAACGCCGGGCGGCGACTCTAAACAGGGCTGTCGGCGAAGCACCTAGGTCTTCCTTGCCATGTTGAGTGAGTGAACCAAGACACCCAGATATTATTGGGTAAACCTTGGGGCCGACATTGTTTTGATCGCGCCCCACTGCGTTCTCCATTCTATAGTTACTATAGTTGAATCTGAGTCCTAAGCGTAATGCGGGGTGCATTTCGCTGATTTTGAGGTCCATTATCAGACATTTAGTTTCGTTTAGATGAAATCTAAACAACACGAACGTCATGATACTCTAAAAAGTCTTCATAGAACGAACAACACTACAAGACACGAATTTAAGGTTCCTGGCAATTAATTGTAAAGGTAAACAGGAAACTGTATAATTACCGATATCGATGTACTGAATGGGTGATTTAGAACCAGCCTCCAAAGTGCTGTCGATTCGTTATGATATCTGTTTAACCTTAGCAATACGTAACGCT ++ ++1544/$$8%)$67=:;776789;=77).32-.%&##%&,.1&'&*$#)($&'(*$)%$#($-0#%'$$#+88?<:=6B5'.69::>>CD@?BA?32?03*0.88>1>5626:((1'$$$)&&)%%*,/0301%$+$%%'8660,%,#%+)6?>7877><-ADDDC3699<6?:;=7?=>;7.''*'4943*#'#%%')(/8802*2((-)(*%(%)+++'7$(38CBA;<=D:('):8<71-+$$@9?>RM5B1B;@8:/'5&'('0((',4220++9;35665*#'?+@B?1,3=@IH??;>@?HC<=B?448454058882',5-2-36-$$0;A@:;@::;(*(3?A>B>689+'0'%'.5$$$>DGCC@@7:6%0%%%.4862+$%&&'8?=<@9+$2.)+7940+).&&&%$&$$&+888;9-(%&'.;A?<=??=<=((,&%/$'(.,/++..((BEB:21220:=845'5834%*$&0,-((.,*514-*3.)6;>::;390086.309>5:,15B>:99>61'%.'./<->34368-:CBA99G=<>?9<=E;;6798D>?D:+>>?>@;2+/**(%$%%&588++1,&+?:@:;==8492B:>?;>;//3$($?6;,21*1&&/0(*-.1-/%(''<=;BJB@?><89=601...//<<9>@=<6@A>'?<;:<>-(:+?@>A@<;=>:0.-/B>=88=BGGD;>@33D@?AA.)89)3(,)&,&0-24,,%&$/4:C;<>@>>=880+999=;669HHC;AB93330/35;66=:9A4.A=C>E==?:41(4=@B@@>,,*))()()-*&$($$#$ +@SRR11410539.2437535 2437535/1 +GTCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACGTGGCTTTATTAGTTGCATTGTTAACATGCCAAACAATAGGTTTATGTAACAATTTAGCTCCTTTCTTAAAGAGGGTGTGTAGTGTTTATAATCAATAGCCACCATCACCATTTAAGTCAGGGAAAAATGTAACTTTAAGCTCTCTTGAAGCAGGTTTCTTATAACCAGTTAACTGGTTCGTCATCAACAAATTTGATATTATCACATACAAACTTAAAATTATCGAAGCTTGCGTTTGGATATGGTTGGTTTTGGTACAAGATCAATTGGTTTGCTCTGTGGAAATAAGAATTGTCTTTCTTATAATAATTGTCCAACTTAGGGTCAATTTCTGTACAAACAACACCATCCAATTTATAAGTAACTGGTTTTATGGTTGTTGTGTAACTGTTTTCTTTGCGGCGCGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +$%##=9:H@<78GF>:8977:448<=*AJFDH@597:<52.)()6866'-/7;:>;+768BEDB9??G>B//A=864013803..009=>A@<0167>@C@DF/:,8C@:@330//%)-)/C?DAA;=AAE>G?88),*79;=:13'$0=??C/$%8:7<78;66:=?>*>A?CCB?AA=7::4/%1=6ANJGMC=;85-:=??AA@D>G?9;ACE9;:>@HCC=7::C56++2AABCFC?@4-G>A<=.:,((<:;AAB=FJIG>@:3900>>FMKE@>LJG6;?==;*0>@9:LKRFA6768,289I))CA<59%&)-;<8;'/44=F?@DIMEH705?DEDFDL::;BD@AB@>??4+?6:69CFCDB@?AFBA8971>?D&&E=>=IGBF0BFDBA:;>?+ENCB@)/<@:AIBHHBA@><:3/1==89B<9/-& +@SRR11410539.1908484 1908484/1 +TGATGATATACTTCGATTCAGTTACGTATTGCTAAGGTTAAAACAGACGACTACAAACGGAATCGACAGCACCTGGTGTTGTTGGAGAAGGTTCGAAGGTCTTAATGACAACCTTCTTGAAATACTCCCAAAAAGAGAAAGTCAACATCTGTGTGTTAGTGACTTTAAACTTAATGAAGAGATCGCCATTATTTTGGCATCTTTTCCTGCTTCCACAAGTGCTTTGTGGAAACTGTAAAAAGGATTTGGATTATAAAGCATTCAAACAAATTATTGAATCCTGTGGTAATTTTAAAAAGTTACAAGGAAAAGCTAAAGGTGCCTGGAATATTGGTGAACAGAAATCAATACTGAGTCCTCTTTATGCATTTGCATCAGAGGCTGCTCGTGTTAGCCGCGATCAATTTTCTCCCGCACTCTTGAAACTGCTCAAAATTCTGTGCGTGTTTACAGAAGGCCGCTAGGTGCTGTCGATTCCGCGCCAGTCGTCTGACGCTCAACAATACGTAAC ++ +%(&*$$&'-,,./&$$(-4-7@D@>;>;:=;6'89(@AC>=9'9--1+;;;957:;94)/46939-.(,,,9:9))=768/@<;<=8:<+89)5(().37748B?BEC:64$'$$&%&&+563313$'$@A:%$(*&...1:>01/.,+$$(,)+'*&/8:;BFE925566789864D'4../-**077:5FFIG68>>:9;?@>%3(./0137-6:2/405777%4,-04857-/%)('&,,%55646;IG;3:=86?DH><;<.6./,,-''.>AA78;<51+19@@>ARC@@3.-:CEB=AA%658//37+42))?AABBIFJJIEEAA041++46//)81(BCA::/*#%)%%*/;9:B:96=9>?N;C<93/.56@?>76981C8)+$%%%%8<@=E;<:A?858?GE<<7@BABA?/>(?BC>>9581+29>7;%,-45'%/()*=DCBE=8''3)%&$&+&&8:4-%**26?E>?:F>=>?@5$3)1///2=@79:::12=D999I?EFCK=5??>?@GG?=34*54835>BG=@9;:JLFB?>%&<+1C==2>15$8::0004950=++89%3=<:42014&&&(+,04?;25/,(&%2-42323-00():;:;3=C@IFID>5.0A38-0C8?42(62@891-.*2%$#%:;=DA%%>009:668=9;@:?@GF?DFFA762897/+,(7?@@EAA775/1'/28>33:@,+,)&)454>A=9C>0001201','=?DE2AC@5)//74,;27<>00,00/))888C@=9854.459//9%8<>@EF?BBMKI98C76915<0:CDB;=*(((///66>>FDB97)) +@SRR11410539.586359 586359/1 +CATTAGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGTTTCCACACAGACAGGCATTAATTTGCGTGTTTCTTCTGCATGTGCAAGCATTTCTCGCAAATTCAAGAAACAGTTCCAAAATTTCTTGCTTCTCATTAGAGATAATAGATGGTAGAATGTAAAAGGCACTTTTACACTTTTTAAACACTGTCTTTGCCTCCTCTACAATTGTAACCATTTAAACCCTGACCCGGGTAAGTGGTTATATAATTGTCTGTTGGCACTTTTCTCAAAGCTTTCGCTAGCATTTCAGTAGTGCCACCAGCCTTTTTAGTAGGTATAACCACAGCAGTTAAAACTTACCCTCTTGAACAACATCACCCACTATATATGGAGCATCTTTCTTTAAGAAAGTGATGTCAATGTCACTAACAAGAGTGGCAAGTGGATGAGGTGCTGTCGATTTCCGTTTAGCCAGTCGTCTGTTTAATATAATAACTCTCATCTT ++ +$###%$&'-1/4?@GFCBG?99=EBHHEEBJI=:=E>?:(53,022>7@FD76CELC=EB./;;8>=?--,9:8>>BCB.4::-568/),,+,2017=AA4,*=8;BB@612%.;<989;?>EB>>@8=@>:24$&$'54--:;?@?>@B3JCEBB=6<726=@=B>=<@9:BB@<7869>9@?A>;2/)$$57CEE8@560#678=@::04(=<>?D?58AF>@?=:7;>9:GGB<:5:.44;7++;<>7;-,(.%-+.33%%&-:://45683?>333-7>8>>@A9::97)=??B>;>;:BDBH9<<>56+874:C9>?50><>@?9??/9;;:78/1.5665$%%104<52**2;59@4092,66:,---5)$%$$,),+&*2%$(+-%%&%%#$$#%#&&(')'$'( +@SRR11410539.786146 786146/1 +CATTGTACTTCCCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAACCTTCGCACAAATGTCTGCCAGCTGTCTTTGATAAAAATCTCTATGACAAACTTGTTTCAAGCTTTTGGAAATGAAGGTGAAAAGCAAGATTGAACAAAGATCGCTGAGATTCCTAAAGAGGAAGTTAAGCATTTTATAACTGAAAGTAAACCTTCAGTTGAACAGAGAAAACAAGATGATAAGAAAATCAAAGCTTGTGTTGAAGAAGTTACAACAACTCTGGAAGAAACTAAGTTCCTCACAGAAAACTTTGTTACTTTATATTGACATTAATGGCAATCTTCATCCAGATTCTGCCACTCTTGTTAGTGACATTGACATCACTTTCTTAAGAAAGATGCTCCATATACTCAGTGGTGATGTTGTTCAAGAGGGGTGTTTTAACTGCTGTGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTTAACCTTAGCAATACGTAAC ++ +&%$%))(788&+3:D3@=?BC97222).;BABC-DDEILFB0@D@6533(,0326.2/26087>&'$)57@88>@@@?;91>,('&2/@@C;GNDDDDFE86:BEAAIJ<==?62:>C014@CCE>569;==))+(23.074413(*,'2,--4<45''7:>779<443<=45HI?AEHF7FB@?=AL4.(,-6-934<>=38?KG>FFIC57?=?EDDHD@GED@..1BCGCBCAB=?>=92%%:/.44>><82:99D<;CDH?C=++'.5*//('%)27865,+$%$(&4479@EGBCC&)-)7846715297DFHABCAG@>><6+.+2)/1-)246/389;<@=EDK=???8:99,56<BB889:::?@?@87+->>;=:4--@AIL@B<@AC=<8<184.-&('#%"#$%%626=<<6+(,&*2001DONCDAB>AA;9:B;7889?//6/2;:@8:11BC8...2093A>1,549<8778B?=6368:BB11*)7')-/.AB>EFD;>>??;JGI;4<9F?IC<:H@;CHLME4-D0.7/@D@E@B;?8.?;8><@A@AG8F;=6,;0HJFB;;A=GDHC>>C7.465:<=<@LCA@4><:=@CD8:@:=A@FG:C2>?ED18C=<=<;(289?08@B=<907-:;9BAD?;0,*$&+77,3;;272577=GDCAAED>1+8786;-;D@;><8>A<;6689@A;-798:<61,/304''&&&''043.&&B@A95)+ +@SRR11410539.2006663 2006663/1 +CAATGTACTTCGTTCCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTAACTTTTATCACTACGCAACTTAGATACATTTCTTTATTTAACAAAAAGGTGCACAGCGCAGCTTTCTTCAAAAGTACTAAAGGAAACACCATTAAAGACTACACGTCTCTTTAGGTAATTACTAAAGAACCAATAGAAATGCTTTGTGGAAATACAAATGATATAAGCAATTGTTATCCAGAAAGGTACTAAAGGTGTAGACATAACCATCCACTGAATATGTGCTAAAAAAACATCATTAGTAAGATAAAATGTCAAGTACAAGTAAATAACAGAATAAACACCAGGTAAGAATGAGTAAACTGGTGTTAAACAGAAGTACAGTGAATGACATAAAGGAATGATAAAGTATTAAAGGCAACTACATGACTGTATTCACCAAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACTAGCAATACGTAACT ++ +6+,++-//049;B9'.9:9551:CA?CB:?=?:@@=?<;3522190<<9=3<:<5:@DD;:;=>++,.*7>DCABDM=LHE@D?@:9/125.%(.@-9889=:52-6%%*4140(@H?33:=48780('6?=?7@BCCBHNB/A22B0;??=>GEMI=@>@=:<9B?;@DHG,BH=:C:;;@>;A<79GABCAEEBD@AGIAG@B5<&&5?/;86)017));;.+0:.2,+.24>???@@88;>9>@;?;<89=6A9FI;+))*+A<>BI=2<7CGFCC=A:A>CGFHJ8,,>A?E9AC<HL?)9EHF@HB:6>>=?669D8=AEC'+9>@>FD;===C?35=CDME@IB;=89<;421-%%#$2(///..<<6>?2* +@SRR11410539.2324982 2324982/1 +CTGTTGTACTTCGTTCAGTTACGTAATGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCATGGCTGCATCACGGTCAAGAAATCAGATTTAGCCACATTCAAAGACTTCTTCAACTTTTTAAGAACAACTGGTACAACAACAACCTGCTCACCGCTTCTTGAGCAGTAGCAAAAGCTGCACATGATGGAAGGGAACTAAACTATAACTTTAAGGTGCCCTGTTGTCCAGCATTTCTTCACAAAGCTTGTTTCTACAGCACCCACCATGGAAAGCAAAACAGAAAGGTGAAACCATTTTTTTCAAAGGCTAAGTGACATCTTTAGCTAAGAGAAATTGATAGTAACTGGACACACAGGCCTAATTTAGATGATGATTCTACTCTGAGTTGTTTGCAAAACTGAAAATACTGATGTGCAAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTCTTTAACAATACAT ++ +'$%$%.+*''''-0+-5-86:.(($''%,5//4CIEEF==113/76989>68,2$%5797:1,),--,)24()((#$#*98<&0(($1$%&**'%20159;6C6==7DEHC?@A/6+%-0>==>;:6;ABA:=BC==6-)%($&*&&%&/--7//0)+14+/%$$#$%.129@@77/=>D::BB20+11('$$18337)*,00-%..)1/1$'&$('%$-1,'(-*5568=?>@B=88@<>D@@CACE?0,,..()667:>:922,--+..,**&%+864637-(7>>E?8--7.'.,6388&669:;QIB>:477/15.0%%%#%%%*-,),,6<<90*..%1'/16-%+*3367;=>?;75-.-+(((((00->B?968E@.6)>8=799>+A==@D3.*(''%**+-1)&&99:67%248;:>=?ABH39?A<:?D@FCDADI=A56<:54>*%%+66?2:1<@<9:81;9;;A89CACBGGHGDGD:BC9FCDCBMEDHBD?;DF:;B??>>DIGF>.75;B94=/09?B=?G,='66ABG?A?<=?@./)%+=+47=?224;=A&'%&&('/?=>BBCDF<9B?GGJOLFBD=892=<>;<;,,('$$,'247A>:<=;?==789344?:(>?23,99:<<()*+0387++34429:<952-$+$$%+'-$$$::78<8'-5.1<861&**$-*7EGA=A8;*#%5'%38;?B=>*)()))*'166/....*8C?@B%:8=98:)/=?:BEDE:90;:8:>4)$$1%23-.:22@AAB*/22379<%.,(99?=DFIB545<;>A=3).;:((3+/116,$)%;9;:77:8>AJ:EE?;JD?67>@BD;581*/.45+,CDB:9=6439+,,6;%$2C2GIE00=DKF=..-,41AB@='',(%%('$BC8@=/((((0402;2>AI5B:>@<''&'(((,',55%&/1$'%%$$$3.--6.,%',/6/37@@FC?BDC<=>>CACAC>/00=>@ER=?66?<;?B>;?%=45%3#6@654*8?;9@A7:@=:C?&.5>7??21:98<6>>@A.>JIEI76<6455350''),/08<>?@9:B@'><&&3,*,520+)%&(&:BAFD;A>9:>994&&*;;:;9B@=EFHDA???2,>C9*5DA614-.;.>1>5?1C698B;8598=<@?E56/*-&5*;FA=;:>=><;=8846/,$),;;FF@>GRL1&5C;;9;=:=CABA/.881@;88<:==@0026'3$9-&7-6:@;>?++48AA@9<%%0/97980$$,*)%&'&%'(&0//0/*$$%'7;4899+1%,,>5668874(&1><97889626)-$(:78,;+12-*3.982467%47@DEAHD<>A52399??3333%)(%&$(7),43,6055-3556.39;:>;4*)(048;=?>8:@78,2,18-/.//.0.,,,%% +@SRR11410539.1516895 1516895/1 +CAAGCATACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAAGGTGTCTGCAATTCATAGCTCTTTCAGAACGTTCCGTGTACCAAGCAATTTCATGCTCATGTTCACGGCAGCAGTATACACCCCTCTTAGTGTCAATAAAGTCCAGTTGTTCGGACAAAGTGCATGAAGCTTTACCAGCACGTGCTAGAAGGTCTTTAATGCGCGCACACTCAAGGGTAGCCATCAGGGCCACAGAAGTTGTTATCGACATAGCGAGTGTATGCCCCTCCGTTAAGCTCACGCATGAGTTCACGGGTAACACCACTGCTATGTTTAGTGTTCCAGTTTTCTTGAAAATCTTCATAAGGATCAGTGCCAAGCTCGTCGCCTAAGTCAAATGACTTTAGATCGGCGCCGTAACTATGGCCACCAGCTCCTTTATTACTGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAGCACGTAAC ++ +2&&$$%%%,,.48:30)A>A>@;4=/6562.-2@HEAC:-(3(0,*,%&('(&'9;489<;A:C6=ED2@>@=?@59?5758CD9IG??@?;@120*,)/%%:67AB>B1?;@9;DDHHFGE@8@/.0;;<>B<8<44-'&A@?,8(539==>:=>77''85-*'%%&-/)$$)*0-=-:<42.',4;:8@:21-,A=9646>?;AFGGB>D>@@::?A879A??-7:1''446AA-*3ECF@+-1G3:CA>96>965?=>G:@6?<;BB:137)C*;?<54@AB?AFDAAA?@/'CBEICCBCRN;00-%907=9:2+,/,*)#&8;=?6A;:?>=*2*+A:;8'$*'0>BBHJB@B35)*'**&;;2$(% +@SRR11410539.1391150 1391150/1 +TATCAGTGTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAAACGGAATCGACAGCACCTAGCCTCATAAAACTCAGATTCCAATACCTTGAGTGTTATCATTAAGTAAGCATAACAGAATACATGTCTAACATGTGTCCTGTTAACTCATCATGTAGCTTTCTTATGTATTGTAAGTACAAATGAACATCAACATACTCCTGATTAGGATGTTTAGTAAGTGGGTAAGCATCTATAGCTAAAGACACGAACAGTTCAATCATAAGTGTATAATCTGTTTTTGATGTCATCTACAAAACAGCCGGCCCCTAGGATTCTTGATGGATCTGGGTAAGGAAGGTACACATAATCATCACCCTGTTTAACTAGCATTGTATGTTGAGAGCAAAATTCATGAGGTCCTTTAGTAAAGGTCAGTCTCAGTCCAACATTTTGCTAGGTGCTGTCGATTCCGTTGTAGTCGTCCTGTTTTTAACAATATCTGTCTTTC ++ +%&''#$)'*(*,1,04<4/9A>910999<416,-.+7:564<9<95500*1078847)+*375706477,25-**-*3;38>@479.0.%#$%%'1.''150-((3=.7:1)+$#(*++-$%-0;984*2*4,013=<85?:>A@?;==8../((::2*#,%.057..//68=?A;:9/446//6CF77;CF=>@810,)))&2%%/2//26%(965525-482):;>*@>43/;'*:<)+7?93<52597:;*+'*)17800.''&24:552;0-)+$,'+&%%,)(0.2765'('$$'&('.''''),++('*+&)**.-,)'+&;;435BB@8:2+90'-5134&@:=?@;@&BC>94,+6((1)-,&6/+-*+-/3338863.5&&@>CB@EFTJ;:-6'4>308+'/21<>$)**.+'))487..2+,6551-)($%((+%(*%,,,,-# +@SRR11410539.1062869 1062869/1 +CTGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCAAAATCGACAGCACCTAGCTCATAAACTCAGGTTCCCAACGCAGCAGTATCGTAGTAAGCATAACAGAATACATTGTCTAACATGTGTCCTGTTAACTCATCATGTAGCTTTCTTATGTATTGTAAGTACAAATGAAAGACATCAGCATACTCCTGATTAGGATGTTTATTAGTGGGTAGCATCTATAGCTAAAGACACGAACCGTTCAATCATAAGAATTAGCATATCTGTTTTTACGATATCATCTACAAAACAGCCGGCCCCTGGATTCTTGATGGATCTGAATAAGGAAGGTACACATAATCATCACCCTGTTTAACTAGCATTGTATGTTGAGAGCAAAATTCATGAGGTCCTTTAGTAAGGTCAGTCCAACATTTTGCTAGGTACTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +%&$'(120;>A;>FD=57?BDA=@B98576&0')065/51355:=A@2>+/%6$&26@>:956?>;>AB''&$&+&*$%#(1+%-,.>@A9@A?;891401(($&#)%./247C>>A@E66;=>B>72.,--7:8::(;+EIFC9;;5),BBGJC<,.8A4;:>FD=@K6.2<6/49-+3;21;7BBBCCGDAFI85GEE?==@AD-@5;$8@-6=A?C3-9:779;9A@GAB@?:=;BCDB=??A?<88&<<9EE=G/DC4:??0B/0619;6=756'<7;/544?C@;=<@=>4559:$+))'*.,.&*%*,))-1:>@BF>?>C?>?0.2,,-0@.BBEC=>?BB?,--/6?;B4D:6-/*@?<90KJ6@BI.&7&%12;AC=?E@>@D<80/=(40-9>??,8.0&'489>CE>EDCGB@-C*@>AAOI>:A=:=?CIJF34D?:4=6;=ACA@96))'01A@>A>?@AB?BD=GD>EEDD?00<>DD@@JKKGD35G37(<@3CBA24$.=@?>>@>@A1:<95<><97)9=:=BA297);ED,76'(*8:@BEFD@;<;7@D?8=@168:/'*%%/+85699<>>758:8EEEBD;;++/89.:=@EE<;:D;>C>?7AEFEBKE=?BBMFEB?E>A24/.-619;=AAF>5. +@SRR11410539.487450 487450/1 +CAAAAATCAAGTACTTCGTTCAGTTACGTATTGCTAAGGTTCAAACAGACGACTACAAACGGAATCGACAGCACCTTAGATTACCAGAAGCAGCGTGCATAGCGGGGGTCAGCGGCATACACAAGTAATTCCTTAAAACTAAGTCTAGAGCTATGTAAAGTTTACATCCTGATTATGTACAACACCTAGCTCTCTGAAGTGAAGTATCCAGTTGAAACTACAAATGGAACACCATCAACAAATATTTTCTCACTAGTGGTCCAAAACTTGTAGTGGGAACACTGTAGAGAATAAAACATTAAAAGTTTGCACAATGCAGAATGCATCTGTCATCCCAGGATTAACACAATTTGGGTGGTATGTCTGATCCCAATATTTAAAATAACGGTCAAGAGTTTTAACCCCTCTTCCGTGAAGTCATATTTTAACAAATCCCACTTAATGTAAGGCTTTGTTAAGTCAGTGTCAACAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTGCAGCATAGCAATACATGGC ++ +(''((&%(#$%&&%&(*3?36.,:=CE?97794;243(1((28:(.92;6=;>><;?<1<'7$+*0002/6/102-8.-66*9/.99FCD@/<+6$(,,.*%%%,$.9<@>51*+3;9;<277512,5($'0:/0A02A30+-,.2>?=;?;867:6+'3B64,6==7320+'&))&(0797(0,%'35967>AK:;9;BE=8;@8:9*(,+,27;997--:*9(1-IGCE?GDDC9=7011.047B=7.;*))349:CE@B??FADCKB@@C:<6@;KF=<573))=FB9=<1@.DGIIECC>+*<:;?99>>8**+?AAA?:;6,#(-EDCB*+++>5=@67;77:/18=579<66<;;<<8::AB95.0011'((*+010$'*&-(@??=8/&&/$,'%% +@SRR11410539.299203 299203/1 +CGGTGTGCTTCGTTCGGTTACGTATTGCTGAGTTAAACAGACGACTACTAAAACGGAATCGACAGCACCTCGGTAAAGAGCTGGTGACCTAGTTACGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAAACTTGGCACCTGATCCTTATGAAGATTTTCAAGAAAACTGGAACACTAAACATAGCAGTGGTGTTACCCGTGAACTCATGCGTGAGCTTAACGGAGGGGCATACACTCGCTATGTCGATAACAATAACTTCTGTGGCCCTGTTAAGTACACCCTCTTGAGTGCATTAAAGACCTTCTAGCACGTGCTGGTAAAGCTGCATGCACTTTGTCCAGCAACTGGACTTTATTGACAGGGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCCCGGTACACGGAACGTTCTGAAAAAGAGCTATGAATTGCAGACACCTTAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +'$%%%&%-//146/&$)'+,1.-.00)/,&'7/.%)'1.4025.-.(#%0461;,0,<820)+*%(%568=(-(&$')&763)+'&%*)$&'%2/@3;EBDCEB;=6>?769@?DDCFFCJD>AB@<6+%'*%---&-D=9&877//6/28:44)5:C=59=::.01?E>B>BE=B@:;EIFBB>?=738703>-17:AC@8*2.6>A>87688831??@?214;=AE<2BAA:>E78<;;==4,05534<873+*$+)'-014--./6688.'+#$%($$8AB@BA<39/5?@CFGHIK84A;?1.;-+5'**(27C@CD@K?97253,(),002<8<ECBFHFBBBAHC:A9;7,6*'''*2:-3$'@CC?F@PH?@B@J3,&*$*$/66:324;:@9:*8<;=<=;;BBCEB@=C;:KE;=;BD?9:64;>>BEABAG?:4577877>??CB.1&,% +@SRR11410539.1457199 1457199/1 +CGATAACTTCGTTCGGTTGCATTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGTCGCTTCCAAGAAAAGGACGAAGATGACAGATTTAATTGGTTGCTTACTTTGTAGTTAAGGACACGCTCTCTAACTACCAGCATGAAGAAACAATTTATAATTTCATAAGGATTGTCCAGCTGTTGCTAAACATGACTTCTTTTAAACTTAGAATAGACGGTGACAGCAATTTACCACATATATCAATGCAACGTCTTACTAAACCTATTAGCAGACCTCGTCTATGCTTTAAGGCAATTTTGATGAAGAGTAATTGTGACATTAAAAAGAAATACTTGTCACATACAATTGTTGTGATGATGATTATTTCAATAAAAGGACTGGTATGATTTGCTTAGAAACCCAGATATATTACGCGTACGCCAACCCGCGCGATTGAACGTGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAGCCTTAGCAATACGTAAC ++ +%$#%$$#&*(79*=,3;=++&%**,,&)1..4>=;><1*-,(&$&)$&*/03$*$09??:2/0:8>?CE>993468*/*,-965&':A:118:FHBD04,,AD<;<<>,.6@/6;><99950103>>//%)')&&#%315<:DA25>3@1>BB?GGBGH61('#$*$%%%%&(.567A@CJ>@>EB-213+**$$$$$'%(*0%:453-,.,'*(&.+,79<<>612&&(%$&*1))$&'&--77A;42:3@=?=DD7&((.0%5/499<;4$$)'%*645355;:7(=?8GHN8$(;=@9:79:.154:732312120DE4B00=99===?A:FE?E@C05B?DGCCA1(&(*11=;B>B<;>:<8=<363-8566,,/($$&('($$-6.:>:?@:+>?53E502<''(.1=III?9=?@810B<:4,% +@SRR11410539.394448 394448/1 +GTTGTACTTCGTTCGGTTACGTATTGCTAAGGTTAAGCAGACGACCTAAACGGAATCGACAGCACCTAATTTCGGAAGAAGCTGCTCGGTATATGAGATCTCTCAAAAAGTGCCAGCTACAGTTTCTGTTTCTTCACCTGATGCTGTTACAGCGTATAATGGATTATCTTACTTCTTCTTCTAAAACACCTGAAGAACATTTTATTGAAGCCATCTCATTGCTGGTTCTATAAAGATTGGTCCTATTCTGGACCCAATCTACAACTAGGTATAAATTTCTTAAGAGAGGTGATAAAAGTGTATATTACACTAGTAATCCTACCACATTCCACCTAGATGGTGAAGTTATCACCTTTGACAATCTTAAGACACTTCTTTCTTTGAGAGAAGTGAGGACTATTAAGGTGTTTACAACAGTAAAGACAACATTAACCTCCACACGCAAGTTGTGAGGTGCTGTCGGTCCGTTTGTAGTCATCTGTTTAACCTTAGCAACTCTGGC ++ +%77%(',/--181:%*:=@C?CC=@ACA-*.8EC78*0,,1.6,5.22325(+*::;>G9D5>?CEF9:991$48AAC>>F;HA5398?CIJC>FEAC<84?=@GFE?EDALG?MFG=BFHEB??>EFBB74-C>EFG;104<@@)==A9;7,#'('':6:?+6)958:&244;>?'')BC@4*2(.9$88339>-&878<;A7497.%(3BBKAI?01>956;5>9:**/>9:;@G5><-09=6>@BBB83,*&#.=>875@>CDFC@ECGB873@()<94<>@?7@=F;KHFFD89++*8@8.B>8:>899453389?:;:=43-'&&&&++22./89;=9:<=A68(3'(1566;97-0;2*?@??@>8;,*227;?=8'*,-,--,+12B?400,1,)&&)$&3.32*++ +@SRR11410539.2010016 2010016/1 +CATTGTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGTGAAGTTCTTTTCTTGTGCAGGGACATAAGTCACATGCAAGAAGATACACCATGAGGTGCTGACTGAGAAAGGACATAAGATGATAGCCCTTTCCACAAAAATCAACTCTTTTTGATTGTCCAAGTACACACTCTGACATTTTAGTAGCAGCAAGATTAGTAGAAGCTCTGGTTTCTGCAGCTCTAATTAATTGGTGAGTCACATATGTCCTGCAAACTTTGAAGTCTGCCTGTGATCAACCTATCAATTTGCCCTTCAGCCTCAACTGTCAAGACGTGAGGATATCATTTAAAACACTTGAAATTGCACCAAGTGGAGCTAAGTTGTTTTAACAATATGTTTAAAGCTTGTGCATTTTGGTTTGACCACATCTTGAAGTTTTCCAAGTGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACTATAACAA ++ +,%%&$%$&2323?.*%9=<8.200/4=CE@@4CGC?C4>9:;672::77::*0'*'698>@>:GGFCBG@ACA9ABB999A:?DD4E;:38>@=@/6013?B?:*%*71242.1+%)+04635734CB??HGI>;<'%(4&'?H>DAADFD;%%23??@@DDF,.5:HH=@;5B67?A;KFQLA>AED=78>767@C*BCFD0A5@?7BAF;;:4512)&&($'%1.,)7909,%(*:779;86:12>/02/2,,*3&&1%$;:<>9??@<9&&-())463-=A=99+8<><>74//7;96?47;77.,4-/-.<7-8**62-79717&&(2>75)),/1324502++A88'<,1*-27..12524>A778:4)$08DBCB0G@B@??D:()*/1;-@C=?>?@A=9-;9=BYI:>;<9MIDBCF;412<=BADFC;;;EDIBA@A:<75:?AH?@ED>.%4-(*8FDGH@7393>/018/9?A??;=>A=A@@60ECECBHAB@>;;?;=>ADE7643%$%1/47A33ADEB?C8@7050/-0>F>A5/;-->;%%=?C@EIGFFDFB6>@BD;?78-*?6>./=059EHGD>BE0?:;:778<88BE;;@=;=:77:CBBCF9;A<4)4AAAABA2*<>BC@D=?C55@AC--86>>=>8:5?A>:5)>0BBFEDCA-D=BDB32.BD@DIE8//-(,-:6;6:66720*.)16:;9<:@@@DCCC>AA>''<90<,,,:*9;E@>A>%*9>>=97:?:;?88>089AA>24G:;HA=,,=/;+ADE@G=@@?F?>76(0%'110=<<=@F?>?CFAHMRC>BEC99221*,335;A@?A@=9B@BHAE@3?/5>ADBB>88949;LGPJEDFEHBD?00C6&$$$1<565)07:A;6;>A><=60,./$$'),57<7BBECEH947<+3)('&'*4445<816,=?ABCGBIEC?BGA0'7AB48<<;;><9<23658((2?ACA;>@>BB6711%+3213*//36253-'99876<6.$ +@SRR11410539.1262957 1262957/1 +GTGTACTTCGTTCAGTTACGGCGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGTGAAGTTTTTCTTGTTGCAGGGACATAAGTCACATGCAGAAGACTACACCATGAGGTGCTGACTGAGAAGGACATAAGATGATAGCCCTTTCCACAAAAATCAACTCTTTGATTGTCCAAGTACACACTCTGACATTTAGTAGCAGCAAGATTAGCAAGCTCTGATTTCTGCAGCTCTAATTAATTGTTGGAGTCACATATGTCTGCAAACTTTGAAGTCTGCCTGTGATCAACCTATCAATTTGCGCCTTCAGCCTCAACTTTGTCAAGACGTGAAAGGATATCATTTAAAACACTTGAAATTGCACCAAAATTGGAGCTAAGTTGTTTAACAAGCGTGTTTAAAGCTTGTGCATTTTGGTTGACCACATCTTGAAGTTTTCCAAGTGCAGGTGCAATCGATTCCGTTTGTAGTCGTCTGTTAACCTTAACAATGCTCAACA ++ +%(+/-7=@<448@<>96.-%')(',((,@@@AD3>:<>>=>76?945.4*/-4<<@=997:;;;=:12-+5,*-3=>A>7$&:3.AAAAA;7&'&:AA:4=;)7&)(124-;;@5?913.:9?CC>A=;;;7$38%:@=A;AC?>>67=9?DCCCEE9;-352=<2+;12>B:JH<955:866@47.?E.2=.'*<B=><86AJ=AB=DFC6EJGA@@,--B=8>A?BEG;FBCDDF9@<576502/2>DB-/5:4C>9B=9ABB,(;B?>@9?;=C@??GC>762B01:8B=69:=:==(*$%%)4>@=?=B?D+?>CC?<@<@>C@AFC<3*),20(7:C><65>574219;=0:?6EGF@A?BEB77:=47;@?DEB><=>9E07::?@8.17?@=>==<.+/*)#&%#,--0&*775J>:>598.++)--6/02597<>F:@FC::314133/()$)$('&)''$#"#%%$%$ +@SRR11410539.1480000 1480000/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAAACTGGAATCGACAGCACCTACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTAAAACAATTTCAAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTGATACCTCACGCAGTATAATTAATAACTAATTACTGTCGTTGACAGGGACACGATATCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCGGCGATCATCAGCACATCTAGGTTTTGTCGGGTGTGACCGAGGTAAGATGGAGGCCTTGTCCTGGTTCAACGGAAAACACACGATCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTGCGTGGCTTTGGAACTCCGTGGAGGAGGTCTTATCAGAGGCACGTCAACATCTTAAAGATGAGGTGCTGTCGTTCCGTTTGTAGTCGTCTGTTTAT ++ +,3420/'&*--3//)7A??:7777914>56-B>C9:037649=623367C>=8A<@=@BDBFFEA12++/077<:9545?6><<4300((,,%32,/.16976..0011$*)-07;11/,918<<17A>?-::@?ED?21&%&&)%'$$''82;3272<8:898945=898F=/):,+3*()((-.8<-'=,:=?LBF?=:AACC:=FF??A67>@E8-07B(/5**1>5326)69A?=:5.,+8:;BBC?;64-6$+$$'%%'/'/47>21/'%.7547%-/2()0>67?71*=49KAGFD=B?>80/(@;JGD7765;5C==C8.<(83E8;556968(+:@1;>GAAC>:0,><>D777<7;0=AE;>;7F67>77930GJ;15<41)4<6;:5(%$,;38:EEH15654:+*22266-&$ +@SRR11410539.2321235 2321235/1 +CGATGTACTTCGTTCTGGTGCACGGCCTGGGACGAAACAGACGACTACAAACGGAATCGACAGCACCTACTTTTGAAGAAGCTGCGCTGTGCACCTTTTTTGTTAAATAAAGAAATGTATCTAAAAGTTGCGTAGTGATGTGCTATTACCTCTTACGCAATATAATAGATATAGCTCTTTATAATAAGTACAAGTATTTTAGTGGAGCAATGGATACAACTAGCTACAGAGAAGCTGCTTGTTGTCATCTCGCAAAGGCTCTCAATGACTTCAGTAACTCAGGTTCTGATGTTCTTTACCAACCACCACAAACCTCTATCACCTCAGCTGTTTTGCAGGAAGTGGTTTTAGAAAAATGGCATTCCCATCTGGTAAAGTTGAGGGTTGTATGGTACAAGTAACTTGTGAGGCCCGCAACTACACTTAACGGTCTTTGGCTTGATGACGTAGTTTACTGTCCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACAGCAGCCT ++ +'$$#$(,((,1:@43*$%,$%#$#&%$##%%$##'4'87::?==6389FF0+5964989>?>GA:F=I>2EKFBB@<<;>B=A@FIB45=FB?@9:1<5-8&:5;DCB;2:=A@@BCEBABCFD?=>974-++*04%*89>0?BGECD?BG<@A?9>7:>??EC/8?8>;=98<>>IJE:>=9A>>19BC+8@?@D:B8:;>=@MB>9=9$$5406-AC?D@CACAE?ADDB=HB;:>?E?4><;>7<<:E=;9=388)64/321*+***&&/0$)+<=>DEJ@//AF<F??=>@A??C*.4=7?366=9/%&>GF7*-?77634123ABA>BE5'6%/,//0,1++355>>9:>BCI<>89CED>C@EFB@8?3:?>88811:22(+9:@?C<<:9.2(+$$'FB?J;5=:=?>@@AGAA:>:8804332(0&&%0&$%& +@SRR11410539.1662695 1662695/1 +CAGCTACTTCGTTCGGTTACATTATTGCTAAGGTTAAACAGACGACGCTACAAACGGAGATCGACAGCACCTTGAAATGGTGAATTGCCCTCGTATGTTCCAGAAGAGCAAGGTTCTTTTTAAAAGTACTGTTGTACCCTCTAACACACTCTTGGTAATGATAAAGCTCACAAGTAGCAGGAAATTGTTATCAGTGCCAGAAAAGAATAATTTTCATGTTCGTTTAATCAATCTCCATTGGTTGCTCTTCATCTAGTGAGGAATATTTATTCTCAGTTAGTGACTTAGATAAATTTTTAATTATGAGGTTTATGATGTATCAAAGATTCCAAATGGGGAAACTTTAAAAGTCCTCATAATAATTAGTAATATCTCTGCTATAGTAACCTGAAAGTCGAGATGAAGCATCTGTTGTCACTTACTGTACAAGCAAAAAAACAATATTGTCACTGCTACTGGAATGGTCTGTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +0$$#$%*/325H<9%+)/.0$$*158666+,=AHB=@4<67@AB@<>IGD?<6B8:866;=<<:5859335:B@;;;?2;&C?>3&12//:80689?<5-;>=23??8.232335/1/0.'''(*).2677:@HH43:<@=7)+%233(5;AE:>====6,$$46449><==9C35%>?>CFBCE;682236==AA=:;==44><-&$&&78=BABD,(D((D=B?C=?ABB??5=6::9@B93;4BBBD?;?>>>=>?=ECFBECB:><;<4<:9A?@8<88>1:55>BDB=''#( +@SRR11410539.1822939 1822939/1 +CAAGACGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGTTTATCACCCGCGAAGAAATACATAAGACATGTACGTGCATGGTTGGCTTCGATGTCAGTGTCATGCTACTAGAGAAGCTGTTGGTACCAATTTACCCTTTACAGCTAGGTTTTCTACAGGTGTTAACCTAGTTGCTGTACCTACAGGTTATGTTGATACACCTAATATTGCAGATTTTTCCAGAGTTAGTGCTAAACCACCGCCTGGAGATCAATTTAAACACCTCACATACCACTTATGTACAAAGGACTTCCTTGGAGTGCTTAGTGCGTATAAAGATTGTACAAATGTTAAGTGACACACTTAAAAATCTCTCTGACGGTCGTATTTGTCTTATGGGCACATGGCTTTGAGTTGACATCTATGAAGTATTTTGTGAAAATAGGACCTGAGCGCACCTGTTGTCTATGTGATAGGTGCTGTCGATTCCGTTTAGCAGTCGTCTGTTTAACCTTAACTTATTACGTAAC ++ +.%%$$#%&')%.-41/2;??9:IHF>./).*213310+3778BBFBGA?>EHFB3=&,$)/668AE>>J<43%):99;9:9:6A<7937%%%.;>,8:16:6776955.&3567;>7-1&1,;CB79K59CB>=?C>DEA:;;>.)<+1::5>??<=8==<;>98<=H@<+1C>A9LOGE;4++$:9C===:/%;9817;CE@.57>=,--$&&&&)%'9641A=BH<@DFAD@C?A?HGF;-.49;;FL>E?;=??9>88-+&,474<=B@KD?@DGHEDECAB:EG;BBMJEEADD@DA>28=:<1-648@>?BKK@?=<1AF:9=A8/1//06A;=?<;:228B<=>?:=DCA:>7@<>,48344022&'065&%%%&&467:<>C==@CGD.BC''&''4')-;;6*4* +@SRR11410539.1352976 1352976/1 +CAGTGTGCTGTTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCACGTTCACCTAAGTTGGCGTATACGCGTAATATATCTGGGTTTTCAAAATCATACCAGTCCTTTTATTGAAATAATCATCATCACAACAATTGTATGTGACAAGTATTTCTTTTAATGTGTCACAATTACCTTCATCAAAATGCCTTAAAGCATAGACGAGGTCTGCCATTGTGTATTTAGTAAGACGTTGACGTGATATATGTGGTACCATATCTAACGTCTATTCTAAACTTAAAGTCATGTTTAGCAACAGCTGGACAATCCTTAAGTAAATTATAAATTGTTTCTTCATGTTGGTAGTTAGAAAAGTGTGTCCTCTTAACTACAAAGTAAGAATCAATTAAGTGATATCTTCGTCCTTTTCTTGGAAGCGACCATAAGCGCGTGTGTCGATTCCGTTTGTAGTCGTCTCAACCTTAGCAATACGTAACT ++ +($&%%+$%*'7:5;498=;5-96344:8483DQIEG:)%*%1,'&/*.22%&024:=?ACDIBIDD>F?CCCNICGIF>9:=GE<>ECCEDD@:5:;8;B??@>A?<:FH?50&$'9A=?756>=>?9:?@@KG>>B7:GECED=8E?@@=C<<33>CDC@B?C>>CDG:=>760;>@=FBGC>@>A:<;>;9CCBCDBAKHEA;>GHGJ<>A>DCGIB;:C:779767B?7=?>?1///66&&;<2+.9<8A0C770<)>9?A@8;>67?<=123:=@??D4D>@@AE><>A?@BB9FCA+70'+)*)-34$9640:9;=8::56:5:=AAN@=;94=2-.)&&'(+(0=38>>AF@<:,*#% +@SRR11410539.1345613 1345613/1 +CATTGTACTTCGTTCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTCCGCAGATTCCAACGGTACTAATACCGTTGAAGAGCTTAAAAAAGCTCCTTGAACAATGGAACCTAGTAATGGTTTCTCTTCATACATGGATTTGTCTTCTACAATTTGCCTATGCCAACAGGAATAGGTTTTGTATATAATTAAGTTAATTTTCCTTTGGCTGTTATGGCCAGTAACTTTAGCTTGTTTTGTGCTTGCTGCTGTTTACAGAATAAGTGGATCACCAGTGGAATTGCTATCGCAATGGCTTGTCTTGTAGGCTTGATGTGGCTCAGCTACTTCATTGCTTCTTTCAGACTGTTTGCGCGTACGTTCAGTGTGGTCATTCAATCCAGAGCTAACATTCTTCTCCGGCGTTGCCACTCCATGGCACTATTCTGACCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCGGCGACGCCGCCGCGAAAAGT ++ +&%$'%+&34:;=?34(,<:BF?DDBG98G>>0AF@,-,87;8=54/50513+'#$*/398)@%;<6670.&&))04:9=34;+2-+4/)*44899ABCCH>5&(()<=*))&4?AB?>?9;7:O@AA4,70..()0+819?:**?FDJC8;=@DF=?8ACEBC@@?=69ECC8=239?@GEB@<;@8245++,*4'<>??@=HF.C9678.%&8866EAEDDKG?FC<=1F>A7.7+50(48+/+/07--45>78687<:=9<123689:;BAG?>;=;1-9%%('+46;:=C>=>@?>?>B>D?CBEDCJBD;??@?=CEDEFAE?EDE:9940(%&&$$$&####$$#$%&&$$$&$$ +@SRR11410539.650329 650329/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTACACACCACTGGTTGTTACTCACAATTTTGACTTCACTTTTAGTTTAGTCCAGAGTACTCAATGGTCTTTGTTCTTTTTGTATGAAAATGCCTTTTACCTTTGCTATGGGTATTATTGCTATGTCTGCTTTGCAATGATGTTTGTAAACATAAGCATGCATTTCTCTGTTTGTTTTTGTTACCTTCTCTTGCCACTGTAGCTTATTTTAATATGGTCTATATGCCTGCTAGTTGGGTGATGCGTATTATGACATGGTTTGGATATGGTTGATACTAGTTTGTCTGGTTTAAGCTAAAAGACTGTGTTATGTATGCATCGGCTGGCGTGTTACTAATCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAGTGTGGACAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTGAAAGCCTTAGCAATACGTAAC ++ +#$./5:><<4=:@??8CGFH=ADD>?<<:347DEAAD87799>:9/022?@2-@*/%&(%,6.68BAFCAE=DEEG?<038B=<0%&.-((8<:?ICDCCTE<::DDE:2:CB?3633ABD;?=@GAH<>A'&:C>B>A?4225D907:@@7=BB:3?&BB966/)*7>ABFJHCID@=ACC@A/47?:A>C=DDCIE;DCADE9=CFGAE1=8@8@C7DF=>==,+,,'126;?<3812A@>:@;58FGKA?A>;?HH@8:6?E,,?<:408&(/=2/ACC06/9EFEFF?CDDOI:=<@=H;8:::<,&2((34,$'%%$)+,.9)680)&*..'+( +@SRR11410539.762619 762619/1 +CAGCTTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTGGTGTTGTTGGAGAAAGGTTCGAAGGTCAATAACCTTCTTGAAATCTCTCAAAAAGAAAGTCAACATCAATAATGTTGGTGACTTTAAACTTAATGAAGAGGTCATACATTATTTTGGCATCTTTTTTCTGCTTCCTGAGTCTTTTGTGGAAACTGTGAAAAGGTTTGGATTATAAAGCATTCAAACAAATTGTTGAATCCTGTGGTAATTTAAGTTACAAAAAGGAAAAGCTAAAAAGGTGCCTGGAATATTGGTGAACAGAAATCAATACTGAGTCCTCTTTATGCATTTGCATCAGAGGCTGCTCGTGTTGTACGTCAATTTTCTCCGCACTCTTGAAACTGCTCAAAATTCTGTGCGTGTTTTACAGAAGGCCGCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTCTGTTTAACCTTAATACGTAACTTTTGC ++ +(%$#$%''()''()&#'&*'''+((,375%%1<7=ABFF30,0185;89*'=@?AAA$%=7B>-9858=7>*%/:?8/$%(&$'%''%&)$(78;;6836&&&'&&-=>0($375;8;=45584922-'(&&))),;>5335--*9<<<4561-1-)(,.5&&%*78:443=<23149<<9JD=<+,%$*(%%%FOH7>@EAE?CH?7A444,(2+090187><9;=6)'.**$%(31()%%,0''/-,+&(+')$&'&')784/021+%%*58;7)?7DI<0(&.?CABFEGKLGIHC=@:8/9<%%>B91@@@:8),/0>9:@=AEC=6+1D:AA562626***7;<<:CC<6D:;@-/-,)5<.0.5GB>A0B2;DGI;8<98;&9?:ADDBCAC/HEGE>?>CJFCANFD=87>:879://1@+CCDCHD?,$7,8*+:>=66:=9:)+;;6((''#$%$$#$ +@SRR11410539.287909 287909/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGACGATGACGGATTGCTTTATTAATACAGCCACCATCGTAACAATCAAAGTACTTATCAACAACTTCAGCTACAAATAGTAGTTGTCTGATATCACACATTGTTGGTAGATTATAACGATAGTAGTCATAATCGCTGATAGCAACATTACCATCCTGAGCAAAGAAGTGTTTTAATTCAACAGAACTTCCTTCCTTAAAGAAACCCTTAGGCACAGCAAAGTCATAGAAGTCTTTGTTAAATTACCGGGTTTGACAGTTTGAAAAAGCAACATTGTTAGTAAGTGCAGCACTGAAAAACATAGTGCTGGTTATCTAGTAATAGATTACCAGAAGCAGCGTGCACATAACCCAGGGGTCAACAGCATACACAAGTAATTCCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ ++(#%(((56;9NOLGD>=,0')*/&9:&&&&&,.073**.(6:=A@AE?FDAABC@@:AFH?4C@?FGF>D/0<1*%<81.(=CIGGIFBBD76=BB:6;%446204,*/C?DF;><68?987=>=<11:572-*.)*8=;BBDAD;;CCA21&&''+%%+.27<--/@@?@:FD2'%$,?>9?L=5948B45.D-=AAHE88:?9<;?KN9+--)44''-.*2684A0;FG@?7C/CCCG>C<=PJF054)*%&+-4<-,@;>=BF84AFF?=<@97)++)++&&''$**+963181)-&$+.0/.-)%$'&($%%#$('+*=.&:)2%&146@9AEF@;8:-<.))9'64<1/)./-&&&*'$$%&.1;,,-A:AD;9:88344:9:5=23@-,9>9A@<=-()5537C;<;65=>@>0/$ +@SRR11410539.1060588 1060588/1 +CGATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGTCGACAGCACCTACCTGAAAGTCACGAGATGAAACATCTGTTGTCACTTACTGTTAACTAAACAATATTGTCACTGCTACTGGAATGGTCTGTGTTTAATTTATAGTTGCCAATCCTGTAGCGACTGTATGCAGCAAAACCTGAGTCTGCTACACGCTGCGAAGCTCCCAATTTGTAATAAGAAAGCGTTCGTGATGTAGCAACAGTGATTTCTTTAGGCAGGTCCTTGATGTCACAGCGTCTAGATGGTGACCAGCAATACGAAGATGTCCACGAAGGATCACAGCTCCGATTACGAGGTTCACTTTCACAAAGCGGTCTGGTCAGAATAGTGCCATGGGTGGCACGTTGAGAAGAATGTTAGTTTCTGGATTGAATGACCACATGGAACGCATTACAGGTGCTGTCGATTCCGTTTGTAGTCATCTGTTTAACCTTAGCAATGCGTAACA ++ +0,+'(-(008@?E=31?BCBFDJKKH>?,:;0>C@7;/.%%0*)*('$&/12.&&0254/,&'1>=G/:<881?/09?>07,9A535@/=;;BA347=6@23<;6983#$()'+(.&;@DBCEG?:CAAEAEF54@9;5GE>C<>D?FBE@64649EB=;DGG>55<=9;?E=>>DAACECB/.6.91/08:<53534374<+356,4?@GIBB?BH??DD=*+&(:HA/)9<<>>?535;<>LHI@A>9=32200;22710+).02@2282>+(7/4666%*(,,*4=BB<911;552;9B://6124..09+(5***5>=9=92161.,(&399AA;;<>.--02+/<6=?FCA:2AF=DG@=FHEEG6<-,)78==.?;;864'4'%'8&':;58FFB??=A6ADBAC>?@@F2E=B>A?6.%)**.0,&/0.25CA;C?CA?;>=C?9//,-:<55>)'67/;<;?9821212&$'))/.0% +@SRR11410539.94797 94797/1 +CTGGTAGCCATGATTCCAGTTACACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACAAACACCATCACAACCAGGCAAGTTAAGGTTAGATAGCACTCTAGTGTCAAATCTACAAACAATGGAATTAGCAGGATATCTATCGACATTGCAATTCCAAAATAAACCTGCATCTGTGAATTTGTGGGAATGTGTGGCATAAGAATAGAATAATTCTTCTATTTTATAAGCTTTGTCACTACAAGGCTGTGCATCATAGAACTTCCATTCTACATCAGCAGGGGTACACACTTAATAGCTTTAGGGTTACCAATGTCGTGAAGAACTGGGAATTTGTCTGCTAATAATGCAGCTTTAACAACCATGTGTTGAACCTTTCTACAAGCCGCATTAATCTTCAGTTCATCACCAATTATAGGATATTCAATAGTCCAGTCAACACGCTTAACAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +'&&%*+$##$'$$+-%4,7?@9)5678;-@?@E==.=86-0'((*&-1(2--0;>=>@BGD;A22=<7@;=58<:=>?7BGB@?H5G,=ACC;0.1>>:>GG@:B:/9;@D?@0BADCFB=A4793@EID?BBF?>7@@@AD722.>;?>:-%,.8<@AAED:8311)'%%.+44=;'@AG>DHDD6?5556?=>=CD0.35BEAE:<<=<<+5B>79**(%&'-3+'0114.BDAADDB<:6*,,,/7DCFKCE?>@CEC>?C;=BF=:,07674?B4@BCCDFAEH//(>@AE>8?+//9;9>@@EDF,+21;<34?:@@=<1.**++125BB:>@>@<<$$489=@B;=EBCCAA@FBILG=7/0*$2859;@?<;;>@A0:6>:<:8GF,:1229=BC=>>:@GKB=37@DF=7605<=/->9:@C>63>?=BA@BA@999C@7-+/9832:8=9>ABGG=?GFA??7366?>=8+--$(%%%%$+()/:=;<;8==9<ECEC?B45737.0=5=69EGE>@FFIIFC44=><>40:54%$$37996C=:>98=@BC>.11;=BCLFGCH?=<=3F//>IDA?+?89:63>ECF?C4/96)7'1ABAA;B=G@5@@=D:7+4799:5378252+26$%%)+39:<@CB:;AGAC=><635((8135<9A@@C?0?=KGBD;@=9===AC?<;/2%9<=A6:A;:)4212,/% +@SRR11410539.55398 55398/1 +CGTGTACTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAACAAAATCGACAGCACCACACCACTGGTTGTTACTCTACAATTTTGACTTCACTTTTAGTTTTAGTCCAGAGTACTCAATGGTCTTTGTTCTTTTTTTGTATGAAAATGCCTTTTACCTTTGCTATGGGTATTATTGCTATGTCTGCTTTTGCAATGATGTTTGTCAAAACATAAGCATGCATTTCTCTGTTTGTTTTTTGTTACCTTCTCTTGCCACTGTAGCTTATTTTAATATGGTCTATATGCCTGCTAGTTGGGTGATGCGTATTATGACATGGTTGGATATGGTTGATACTAGTTTGTCTGGTTTAAGCTAAAAGACTGTGTTATGTATGCATCAGCTGTAGTGTTACTAATCCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAGAGTGTGGACAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACCAAC ++ +*%++-+:<=;>=)'=37,15GI@=CA0*.340=::<<>GD81.999:9=@EC@=C@BB=?=>CAB;<9798?==::9?;847<=HADBBLGRHD;=IDJCGGGC:7=:?@?99?;C?.5;>AC<@@ABGC89G2+69:=<:?B12;>D>)D?EEK@C@DCDCF<@?LHGF;=C;A@DCDF981.39@'1A>HGE<>=JIEEADC;;>?863,<<-1>@@@BD<;;:BAF;?CB>?CD@?@E??BC0-.87;?8@?@;;98:5541,ABE@B@<:;GB>?98ADE:;A;?DBDIEKF@00.HH?BB:@>??:;?;?H:;20&.25&(*)/@A>AD<;5814.+087@BENH:<;;<469<187:&&*%((#%#%$#&(*6>:>7==8;>=:/($&'$,1-++%$'%'*+*.53.%%(1/1..*+$%%)/*5#$-&0-24/-%$&*/14,-1.((&')**$%#&%*('.)))*%./58<<>8-,0'+&31522--03569;<695+56(6&62*0$$&&''%$#%*(*.+$55,-.632'%.+./5=:7++,+.))&+&06524<;3++('.33;7++*-*0156=?E?@@<>78::++7,:A46;<773,**,*%(&&+2/311.+'(,&(2/++)'/*),)-//.*$)086::3434/**&%%$%%%)**)*($)$%#%& +@SRR11410539.769147 769147/1 +GTTGTACTTCGTTCAGTTACATTATTGCTAAGGTTAAACAGACGACTAAACAGATCGACAGCACCTACACACTGGTTGTTACTCACAATTTTGACTTCACTTTTTAGTTTTGGTCAGAGTCTCAATGGTCTTTGTTCTTTTTTGTATGAAAATGCCTTTTTACCTTTGCTATGGGTATTATTGCTATGTCTGCTTTGCAATGATGTTTGTCAAACACTCCAAGCGTACATTTCTCTGTTTGTTTTTGTTTACCTTCTCTTGCCACTGTAGCTTATTTTAATATGGTCTATATGCCTGCTAGTTGGGTGATGCGTATATGACATGGTTGGATATGGTTGATACTAGTTTGTCTGGTTTAAGCTAAAAGACTGTGTTATGTATGCATCAGCTGTAGTGTTACTAATCCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAGAGTGTGGATGCTGTCGATTCCGTTTGTAGTCAATCTGTTTAACCTTAGCAATACGTAAGC ++ +)01'74<@B47DE>:<@9&,%%('')+01561>;=>DG6:98:421&/36620:4210+7'...*.'0+778457DB9BD?=@B7:H<@=8EC=54==>>5/;=?B@&-+7>141--.;01(()67:DD:?716;EBBC=<8/,/6?CC?>>D?LJ@@BDCCC9>?6713@>@;5++0:9AG>A@E=CE@DDCPMDKFEB>AGBA=3+5.B8;67DDIDA?B:EC786A35=540.%%8=BHCFF@BIG=>@CBB9>EIEA@?BCD?CED?=B>25$B9455>:C@6/-=;A@5@79BAIHCACG@<4-BAA@+#(>BFC=@?@C<><13>BDC8=.->A9GM??@D978>>>A%%;==ADC5>-39)$.+,124#),078:=/'#$$''$$,(,,/1.,-&(&(.+-229A=?;),*) +@SRR11410539.1331613 1331613/1 +CATTGTACTTCGTTACGTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGCAATTGTTTTTCAGCCTATTTTGCGGTACATTTTAATGTGTTAATTCTTGGCTTATGTGGTTAATAATTAATCTTGTACAAATGGCCCCGATTTCAGCTATGGTTAGAATGTACATCTTCTTTCATGTTTATTATGTATGGAAAAGTTATGTGCATGTTGTAGACGATTGTAATTCATCAACTTGTATGATGTGTTACAAACGTAATAGAGCAACAAGAGTCGAATGTGCAACTATTATTCAGCTGGTGCTAAAAGGATAACTGCCCATATCTATGCTAATGATGAAAACTTTACAAACCACAATTGGAATTGTAATTGTGATACATTCTGTGCTGGTAGTACATTTATTGGTAGTGATTGCGAGACTTGTCACTACAGTAAGGTGCTATCGATTCCATTTAGCGTCATTGTTTAACCTTAGCAATACGTAA ++ +''%&'0-9:>445,8:8>66;-3,+('&*,00<;<=@::>CI?KF>>@D??=@@H@(&'($-=??DB).#%*#%$7882%&'*.%$'&'%*97;,1;<;A657(,2@?8AB??A27C6;3=A0.2;A?>?A@:==3(..)45@88831/36?>C?@88;;BA665*.B;17A)1::9>8.(/3)&%($%,$$%%'-1'**+69&'&$$&%+'()'%#(-99537+/*),$$%&)3400&. +@SRR11410539.1602193 1602193/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCGGAATCGACAACTGTAAGGATCAGTGCCAAGCTCGCTCGTCGCGCCTAAGTCAAATGACTTTAGATCGGCGCCGTAACTATGGCCACCAGCTCCTTTATTACCGTTCTTACGAAGAAGAACCTTGCGGTAAGCCACTGGTATTTCGCCCACATGAGGGACAAGGACACCAAGTGTCTCACCACTACGACCGTACTGAATGCCTTTGAGTTCTGCTACCAGCTCAACCATAACATGACCATGAGGTGCAGTTCGAGCATCCAGACGTTTGATGAACACACATAGGGCTGTTCAAGTTGAGACAAAACGCCTTTCCCTTCTACTGGCCACAAGTGCCATCTTTAAGATGTTGACGTGTTACTCTGATAAGACCTCTCCACGAAGTCTCAAAGCCACGTACGAGCACGTCGCGAACCTGTAAAACAGGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTTTAGCCTTGGCAATGCGTAACT ++ +#')+154679;?>FFJKGNEEC33/?FA?A<7((33=23%)8:9@;-5'-$$'''.11+4=0A>:G>>:06+++12;>?529,$8@@DFHC=C?@C?23DVQ@;B@<>0<:F@?;-->=BBC??><&&913CD8?:D>2457?B:<-440898>FGBAIE?BBB9;''.,47@@ABAABCCE?;?@AC?DBBDBCE>?9@87(&'9<9BA9<.?<8G/><=:<:7&(>7CG45?DH=8@D;4%%94A%%7''8?9I<;87GFDF?9''411&B6483A<;D><==72(%&3??@<9,,-+.5-2..384,/-$&654,*+)?653?<@ED<67:@C?FDDA82/0++%&;@B=<@>?E?77*370?:,/%(3571800'&89388;9=;74:40135-...3;<,(,452142,(2@76=92662>=.56FFK32=47=A?@AB55;925.789?(1444((*53./** +@SRR11410539.1192782 1192782/1 +CTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGTCAGCACCTTACGACAGATGTCTTGTGCTGCCGGTACTACACAAACTGCTTGCACTGATGACAATGCGTTAGCTTACTACAACACAACAAAGGGAGGTAGGTTTGTACTTACTGTTATCCGATTTACAGGATTTGAAATGGGCTAGATTCCTAAGAGTGATGGAACTGGTACTATCTATACAGAACTGGAACCACCTTGTAGGTTTGTTACAGACACACCTAAAAGACCTAAAGTGAAGTATTTACTTTATTAAAGGATTAAACAACTAAATAGAGGTATGGTACTTGGTAGTTTAGCTGCCACAGTACGTCTACAAGCTGGTAATGCAACAGAAGTGCCTGCCAATTCAACTGTATTATCTTTCTGTGCTTTTGCTGTAGATGCTGCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACATGTAT ++ +'&''''66<1:J,8/6DGE>?FFCI;A844/APIHK4?;;B>BE@C7=GIJBAEC@3*%&,2677<=D?7ABA@B?GKC<=KICFA=B=DA/>A>:>?CB@BJ>>F42EJJC:;BB=9;?C?7>==><:.:999=DD)AIE>?FBAABKJKB>:893,3A?<=C:;D?DJL;--46?:>A8<=AA@46>985/;==//>CE./9DCCC>AIF=@;BEG>FE;@CB@@@F@B@;?=BJG>5<:;EF=9;1@GGG=;:33))0/+01129AF>&*$$(.6834?CC9E74@A3&58=>FHB;;(.=AAB<8:BA;87?<>=CD98>=@?DEA@?/02C0>=2H?FFMEB@:879B:;@EFEEHE=;;==?EB@?:5754:27::876:>2267806716,772;ADCDCAC9DB+->?=82416;>;=<95..-,&&(36:;5%$%$$# +@SRR11410539.2215318 2215318/1 +CAGTATGCTTCGTTCCAGTTACGTATTGCTAAGGTTAAGACGACTACAAACGGAATCGACGGCACTACTACCGAAGTTGTAGGAGACGTATACTTAAACCAGCAAAATAATAGTTTAAAAGAATTACAGAAGAGGTTGGCCACACAGATCTAATGGCTGCTTATGTAGACAATTCTAGTCTTACTATTAAGAAACCTAATGAATTATCTAGGTATTGGTTTGAAAACCCTTGCTACTCATGGTTTAGCTGCTGTTAATAGTGTCTGCTGCCTTGGGATACTATAGCTAATTATGCTAAGCCTTTTGCCCTTAAAGTTGTTAGTACAACTACTAACATAGTTACGGTGTTTAAGCCGTGTTTGTACTAATTATATGCCTTATTTCTTTGCTTTATTGCTACAATTGTGTACTTTTACTAGAAATTACAAATTCTAGAATAAAAAGCATCTATGTGAACTACTATAGCAAGAATACTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +-*$'%%%0023=EA/3<7GFGBCFDAA:?4++7@@520&$1>?>@?=9;73)+'/9:>2%)()%'77?<9331043B>:@@BE6;=;AHIBD;44><=?94E6A@8:@A><<&&'9:A:96C<>DF.7+*,460<734($%&*$)8G?BB=B:ADFDCE=;A?=?77.+-.''%$%$&'23234;A85/75/75AB:77$7<:996CB<>9::2-$-$$,77AA?12&-04A@:;:544%79;99-169;572278D@=)579@77;.-649:<8<3159>>@EMK@=18'73&&+%>=><>=7204))/..447'8@=@=10($&'+&2633/$/-0//(6==<=EACAG>GFCB@>ECGFE=?=DBIAB>=9<::=>@===>>DDD8>+678<=ACF>6)* +@SRR11410539.1116391 1116391/1 +TGATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGGTCAGAATAGTGCCATGGGTGGCACGTTGAGAAAAGTATTGAAAGTTTCTGGATTGAATGACCACATGGAACGCAGCCACGCGCAAACAGTCTGAAAGAAGCAATGAAGTAGCTGAGCCACATCAAGCCTACAAGTTAAGCCATTGCGATGATAACAATTCACCGATGATCAATTTATTCTGTAAACAGCAGCAAGCACAAAACAAGCTAAAGTTACTGGCCATAACAGCCAAAGGAAAATTAACTTAATTATATACAAAAACCTATTCCTGTTGGCATAGGCAAATTTGTAGAAGACAAATCCATGTAGGAATAGGAAACCTATTACTAGGTTCCATTGTTCAAGGAGCTTTTTAAGCTCTTCAACGGTAATAGTACCGTTGGAATCTGCCATCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +&,*$&(%.46:BD18488?FB<8754*7;001028>>.,(1'.'(;??AHIAA/2./4:5:06+-*--,.)+,2@9??66&-3:/59:<<>=A;'7<0'&(&-*$&$$*6@@B=592D>:9>422?>(-(+-.145*+*'--+000177:<>91+9079C62E=5E:;>>?=69A7=@?3:;7*.40D<>???62994,+-464D@34>AE>FG983'(38::)*'(('%879:C78791,,3B>>DFG9,*/49)4<=6;:?EF?>@??(89>>8:=CB>@.18;?DBD74FB?DC/.:*0:<9:*+''(%'%*60:9:@II;E<>@DF3>/9CFEGE9>@BFC@NJC//>$*=<@1A.>15;4/079886=/:;:878+;=9-- +@SRR11410539.1996412 1996412/1 +CGGTATGCTGGTTCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAACACCTTGTCGCAAAATATACTCAACTGTGTCAATATTTAAACACATTAACATTAGCTGTACCCTATAATACTTGAGGGTTATATACATTTTGGTGCTAGTTCTGATAAAGGAGTTGCACCAGGCTGGCTGTTTTAAGGCAGTGGTTGCCTACGGGTACGCTCTTGTCGATTCGAATCTTAATGACTTTGTCTCTGATGCAGATTCAACTTTGATTGGTGATTGTGCAACTGTACATACAACTAATAAATGGGATCTCATTATTAGAGTGATATCTTTGACCCTAAGACTAAAAATGTTACAAAGAAAATGACTCTCTAAAGAGGGTTTTCACTTACATTTGTGGGTTTATACAACAAAAGCTAAGCTCTTGGAGGTTCCGTGGCTATAAAGAAGGTGTGTCCAAGCGATTCCGTTTGTAGTCTGTTTAACGCAGCAATACGTAACT ++ +,&+('#%&,$&/(>-1<=;2+<67;)%&45&=>9:>64031A?B=AGD@B7<5:1A:23&%&&'-1148?85%&448>;2,%$+:88>?>=2,>;;DDIGADHH>:;+.4&6,249.%+'('&%#&(,)'(()$&&&1/1>67KGB=BB<=144144('-&&>=8466C:4++/57C>;=AD@3BCE?=?HA?GDD9(/)3A7:71*,-/@@CH6:?ABCE?GGD9:;DCC624(5;015:@CA=?FA===67/0&%+/++)'++0.)57:<889;<:44EKKIL?@AB6><<%2CGCIBF?D><'&;HK2'6?G@OLTED<;FJGFFGGJ6A>=C@?.531A<;6;@E?A@>B9FJ8&.'0*-')%$$)#$%%++(+>?9>?;0.+))5*''()%%&$$)&778:/510.-&' +@SRR11410539.127831 127831/1 +GTTATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGGATCGACAGCACCTAAGGTGTCTGCAATTCATAGCTCTTTCAGAACGTTCCGTGTACCAAGCAATTTCATGCTCATGTTCACGGCAGCAGTACTACACCCCCTCTTAGTGTCAATAAAGTCAGTTGTTCGGACAAAGTGCATGAAGCTTTACCAGCACGATGCTAGAAGGTCTTTAATGCACTCAAGAGGGTAGCCATCAGGGCCACAGAAGTTGTTATCGACATAGCGAGTGTATGCCCTCCGTTAAGCTCACGCATGAGTTCACGGGTAACACCACTGCTATGTTTAGTGTTCCAGTTTTCTTGAAAATCTTCATAAGGATCAGTGCCAAGCTCGTCGCTAAGTCAAATGACTTTAGATCGGCGCCGTAACTGTGGCCCACCAGCTCCTTTATTACCAGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +&''%%$4564?>7?98838A=DEC>A591ACCCEGC==?FJBB?@DA;);77)*&.(+)&&-,55?>32087A;13DA=D566GH:.$;22@B?D;EHIG:5>/,8;;<;A<;575+.%%,%'/6-<6+D@AFA93445969=@34A/82A<9;=<=89;211?794<279B?B969;8:52'-+(*)%$.4)'-03@A=<9>=:>>946-<<=:27344158??=;592+$-?>@KMA@:A>??4;;?;??;>C;8(/0?;BABF;CB67;%&/<5B<619.==659;A2%.=@AHB?@@CFG??FD<=>;:30% +@SRR11410539.1916943 1916943/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTGTCCACACTCTCCTAACACCATCATCATGCACAGTTCTTGCTGTCATAAGGATTAGTAACACTACAGCTGATGCATACATAACACAGTCTTTTAGCTTAAAAACCAGACAAACTAGTATCAACCATATCCAACCATGTCATAATACGCATCACTGGCTAGCGGCATATAGACCATATTAAAATAAGCTACAGTGGCAAAGAGAAGGTAACAAAAACAAACAAATGCATGCTTATGTTTGACAAACATCGTGCAAAAGCAGACACATAACAATAATACCCATAGCAAAAGGTAAAAAGGCATTTCATACAAAAAAAAGAACAAAGACCATTGAGTACTCTGGACTAAAACTAAAAGTGAAGTCAAAATTGTGAGTAACAACCAGTGGTGTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACAG ++ +$%()015-.10:B.=77D@.5.;323%0=-.:=AAEF9A11=8;<87((%'%(*%+346?>@EHE>=G>:;C9@EGB;>$)@22@;>>=2'#053'&,4@>@D5>4;53AC>B<>?98B:95?7?>:::7@/CD8/1.5;94@8;?A>59&&?//<:=@96@45779B(($##%(&$$&2<6AA6675=?AGGIDDE:G>23EDFBJHHB==)-1/''&'6675EFEJF>HIC;$(6*+@A>=IBC>GEB:C:-%A58GG>475441/%')&'(165989>?CAF=:@:>IE7((:7BHE3(.3?5<>C?;449FGJE4+'$)@>;CGA<>5>46:.'3?AB544DHH<7(5%2<B<9C961>A@474B?18@A:AC&7?D:<2-64:B@DB;:8<@GEGFC7B>9=>;CE33$>*259A>=C=FIBBHEEACDDNEACAGACBE@>96DEDH?ED:8>:9>?CB9:>@BAB741'.889;877(/%)'7:@>;5=@A@CCAF@;$'5=@??:?B?778?46@4.>.-:=7FFE=A=<;<18A=<5<6B;5,,.=@:IG@@KBA;<>B=GGDD?A?@(+2847565?=753>>?:ED:>8885BCH>BC<;BD5*+,.*+0/%058?=>153654::;@HCJ@?=86EA=<:,08:C?CCA;22+0DA>8CDCC9@A?=DBCC/:05M=45>:3-/>=35222GA=?93%33)=>>85'4BAAAD=ADGIE8923?F73074416<<<9;>=>8<8;(($#&%&651*0' +@SRR11410539.1463754 1463754/1 +TGATAGCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAATAACGGTTGAGTTTTAACCTCTCTTCCGTGAAGTCATATTTTAACAAATCCCATAATGTAAGGCTTTGTTAAGTCAGTGTCAACATGTGACTCTGCAGTTAAGCCCTGGTCAAGGTTGACTATGAGCATTAACAATGAATAATAAGAATCACAACAGGAACTCCACTACCTGGCGTGGTTGTAGCAAATCACCAGAATCATACCAGTTACCATTGAGATCTTGATTATCTAATGTCAGTACACCAATAATGCAAGCATTTCGCATGGCATCACAGAATTGTACTGTTTTTAACCAGCTTGGCGTACGTTCACTAGTTATTTGTGTCACATAGCGTAATATCATCTGGGTTTTTCTACAAAATCCCTTAAGATCCTAGGTCATGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTCTTAATAC ++ +%-(&(#(*6+59>FD@=78778+>8<<->HHDG>?;=9.6+/5+4682+138=;9=AC9883@:B>>7$$'#&,+$%%/8C@>A;:=3;@CC@DED78?@&7;?999;<:<6;<:.%)4668;36972@:;7;:6CHGCD;;2)%)#)/0,982,;=<>78,:4+$*$%&'%$'.,+,<>==?6:0@CAC>()$$+%,..2145=B=>=A7>4476554,,%&%*.-/))(%%'.+%2'#$##&(&'+)0357?<7-:8''+79>?<>?@BA@G;6?7..520>57?5;/'-*)*$3)(1&&(/0:C>7&&$%$$110-/*0)'*'3+4+.*')4)&''((*(%/,.%%$(')+,-,,$$+1=580@DBCB;*/++018<''5&&)#%+$((++,(**'*()--75GE:<6?>C=9<9;>657)+65-.,$&&*$$%'&%%& +@SRR11410539.276914 276914/1 +GTTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGGAGCTAAGTTGTTTAACAAGCGTGTTTAAAAGCTTGTGCATTTTGATTGACCACATCTTGAAGTTTTCCAAGTGCACTTGCTGTGGAAGAAAGTGAGTCTTGAATTTTGCCAATAGCACTATTAAATTGGTTGGCAATCAATTTTTGGTTCTCATAGAGAACATTCGTGTAACTCCAATACCGGTAAACCTATAAGCCATTTGCATAGCAAATGGTATTTGCTAATAAAGCACCTGCACCAAAGGTCCAACCAGAAGTGATTGTACCCGCTAACAGTGCAGAAGTGTATTGAGCAATCATTTCATCTGTGAGCAAAGGTGGCAAAGCAGTAAGGCCGTTAAACTTTTGTGCACAAATGAGGTCTCTAGCAGCAAT ++ +%*-.<>A?>F.81:@@::8:<;;F5?A=DKDIJC>*/DA<=CHA006BGGL827<=7D920:ACC@>:=>B9D-+))+344;8@>A??<=EDBH>?FHEF>>CA:983()'128;3?A4CC@EF8/278435<@FD;??>8>0//34&-.6'16453&,,-323.3578JHFH9>??GA8FA<4>??86'+090/+:+3/*8',3/& +@SRR11410539.491996 491996/1 +TGTTGTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCATTAGCACCTACTACCGAAGTTGTAGGAACATTATGTAAACCAGCAAATAATAGTTTAAAAATTACAGAAGAGGTTGGCCACACAGATCTAATGGCTGCTTAGCATAGACAATTCTAGTCTTACTATTAAGAGAAACCCTAATGAATTTATCTGAGTATTAGGTTTGAAAACCCTTAACTACTCATGGTTTAGCTGCTGTTAATAGTGTCCTTGGGATACTATAGCTAATTATGCTAAGCCTTTTCTTAATAAAAGTTGTTAGTACAACTACTAACATGGATTACACGGTGTTTAAACCGTGTTTGTACTAATTATATGCCTTATTTCTTTACTTTATTGCTACAATTGTACTTTTACTAGAAGTACAAATTCTAGAATTAAAGCATCTATGCCGACTACTATAGCAAGGAATACTGTAAATAACTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATGTAGC ++ +$'&(%&&+..17H/+$:.57B=DA@@;;977/554-12;:::;;;;6<;?B<=9;<=0)&$%(1319970;?:GA:6166?895BC*,.%099''==A6JEGF@DEFEGK?:@?A@ISD;87:12,/;.*04A?@7772.34120=7@9=@E@B=@:***$$#&&023A>><4>2=A<>EE:3=BCB5585+/DHCDC?%%*$%$,18/*7$$$'2526769II=9;?>822++-%%,4::C
@CE<5:?A2@A?>B=<21/?;88A;<;AD;2+,-&-.88=?B@B><<9=.;,<=CHL66,1,,/=A;047?1BC;=LI?8823.;:78=>@$*$772+7:,39;:7.16+;;98+)650=?9=;==78BC?<068B;CA>6@GKC;;A<9=0100.1/,79<==1(-*:+3'*=4===<7AC.>%;9+,563+414C<911:65DCEJ@?D0)*'"%#%)&'%%&(=364587+,)&'#$&')($'()(),/-766*$$+$$()$%-34:)FIK@;5BKJC=>@=-->&25:81459;6>C:-88=>?@?>:;8578112--D<=;;=<@CEFE>B=ACA226;29=;66/.*)2'22.,%%&8;>IDBFA=B662303*B35A7=>AD@;&&:02)<>16:CEG>@96().,*')&'&&$%'#$*,,/+,0)))/0,***01+57976;B??>?;94+9/@A@DBDE=;5>;63%%-021>@F>FD=>BD;,@>?9?B8DA;@GH??BDG,999?AC?00CAHCBBD@GE>@B=?:1,%&&&:?9>I>4(//22&'('007;B/;=5**3546<842*/*,2//--,#$&$$# +@SRR11410539.1929900 1929900/1 +CATTGTACTTCGTTCCGGTGCGTATTGCTAAGGTTAAACGGGCGACTACAAACGGAATCGACAGCACCTTGAGGCTGGTTCTAAATCACCCATTCAGTACATCGATATCGACATTATACAGTTTCCTGTTTACCTTTTACAATTAATTGCCAGGAACCTAAGTGGGTAGTCTTGTAGTTTAGTTGTTCGTTCTATGAAGACTTTAGAGTATCATGACGTTCGTGTTGTTTTAGATTTCATAAACGAACAAACTAAAATGTCTGATAATGGACCCCAAAATCGGCAATGCACCCCCGCATTACCTGGTGGACCTCAGATTCAACTGGCGTAACCGGGAGTGGAGAACGCAGTGGGGCGCGATCAAAACAACACGTCGGCCCCAAGGTTTACCCAATATACGTCGGTTCACCGCTCTCACTCAACAGCAAGGAAGACCTAGGTGCTGTCGATTCCGTTTGGTCGTCTGTTTAACCTTAGCAATATA ++ +%#$%*0/679?CE=(,),3'356;@C,*)((0EGC7:7>+144&%$/*-02*;9;33:=>B;;@@D;=::=48=48:@@=:=<::6558)+)-(($/.66:?@=;C=B89+6364<579:IF=7(((--)+,55<@?8?04-42337B@AID4+.&&10+-./;<@:AA;6<<9?=E@J:51,52-'%':::8600=:>6:=DBE@=?AE886BHJ5,5&)2),;;=A=;986$33680)++9<;A558;AB5,8'%,6%%%$(,22*733:>@?9=62@DBB<7>?<>:-,1110$%6857>?B46@BC8=8.&/.+*&%%& +@SRR11410539.618447 618447/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACACACCACTGGTTGTTACTCACAATTTTGACTTCACTTTTAGTTTTAGTCCAGAGTACTCAATGGTCTTTGTTCTTTTTGTATGAAAATGCCTTTTTTGCTTTTGCTATGGGTATTGTGCTATGTCTGCTTTGCAATGATGTTTGTCAAACATAAGCATGCATTTCTCTGTTTGTTTTGTTACCTTCTCTTGCCACTGTAGCTTATTTTAATATGGTCTATATGCCTGCTAGTTGGGTGATGCGTATTATGACATGGTTGGATATGGTTGATACTAGTTTGTCTGGTTTTAAGCTAAAAGACCTTGTGTTATGTATGCATCAGCTGTAGTGTTACCGCAAATCATATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAGAGTGTGGACAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACTTA ++ +&55.1-=AB9;I2:<;FB0=@CDDE=><2**@LIFK@A66A>>A@9D?DE=?02;>::,,,0+-,/,'89@CHCCGFC:<5H>:;42>8445648;9@<8NI='&EFLC@?GEF87755BA>79EEE?EE=E?IGHC@@<++:B>@@?:8;A>BAI>>9<6(+37:&?@<>4>B0/.<;?7*.,-.6:EBOE;=D95$))'9<>@;587A:?;=7>>'/<@B?H?/?FD@?3DFB?==45D?13:;?B7AI3*?08;GFE?;;D?=:3)(1'##'.-;0:?CACB><)9<0?C8?@72&+7650%""%++.+(:(.0>A>'9$9;;EIG?B:.08:E?=33B=%.CCB<;8896+)6638>H84=;<7,)+4?<>HD=@;GDH9>=?8=9=@==BE/9:@DC;4>?D>>=,,&&&$ +@SRR11410539.513337 513337/1 +CAGTATGCTTCGTTCAGTTACGTATTGCTAAGTTAAACAGACGACTACAAGCAGATCGACTAACACCTCCATGGCGGAGTTGGTACTATTACCGTTGAAGAGCTTAAAAGCTCCTTGAACAATGGAACCTAGTAATAGGTTTTCTATTCCTTACATGGATTTGTCTTCTACAATTTGCCTATGCCAACGGGAATACGGTTTTGTATATAATTAAGTTAATTTTCCTTTGGCTGTTATGGCCAGTAACTTTAGCTTGTTTGTGCTTGCTGCTGTTTACAGAATAAATTGGATCACCGGTGGAATTGCTATCGCAATGGCTTGTCTTGTAGGCTTGATTAATGACCGGCTGCTTCGGTGGTGGCTAACCTGGACCTGTTATGCACGCGTTAACGTGGATCAGCAATCAGAATTAACAACTCTCGGCGATGCGCACTCATGGCAACAACTCGACCAGATGCTGCATCGTTCGTTTAGCAGTAAGTCTGAACAACCACCAGCATTTTTAGTAACGCGCAGCCC ++ +-(----'$++-.1,0(:93+;6>:@=420(((0'''%%#&$)&$((%&#%&(#$)*)%##$%%-'))0$-%-',1+.%*44%&((4524738<:GDC>D8;:@@>34/(3554>49DCE>@@;?AF@@;320;9:60/5257-1-*78&*&(277804&364))*+)$$$'&'&,6+)+(.00.8--5&+3.,*$&(+'.:>7:B;:C>?=B;=>.%4;9712631/0048DA9)*$'(,37<2?7=EBIB@;<3EJADABB>A.&9,47,2>/1./0:=EC>:?*+>??94+<<;:<@@417-9=>=.))1$%*+%%1'*-.%$$%$&$%#$,)*%***,/&$'%#%*''&%(((%'+'&$&$$%%$&(($%#$'*)'*)$))%'$%&%%%*,&)#%%$#')$%(%')/')&(%&%&$$#&)&%$()'%$$#%#$).,,%(--++%$#"#%%''*.4$&$$$'(%'&%%'%$'&)%%$'%##$#$$'$$##$% +@SRR11410539.286573 286573/1 +GTTGTACTTTGGTTCAGTTACGTATTGCTAGTTAAACAGACGACTACGAGCTGGAATCGACAGCACACCAGTTACCAGAGCAGCGTGCCGCGGGGTCAGCAGCATGCTGGTAGTTGTAAAGCTAGTCTAGAGCTATGTGAGTTTACATCCTGATTTATGTACAACACTAAAACCGCCTGAGTGATATCCAGTTGAAGCTACGATGGAACTGCATCAGCAAATATTTTTCTCACTAGTGGTCCAAAACTTGTGAGTGAGACACTGTGAAGATAAAACATTAAGTTGCACAATGCAGAATGCATCTATCATCCAAACAGTTAACACAATTTGGGTGGTATGTCTGATCCCAATCATTTCAAATAACGGTCAAGGGTTTTAACCTCTCTTCCGTGAAGTCATATTTTAACAAATCCCACTTAATGGCAGGCTTTGTTAAGTCAGTATCAAAGAGTGCTGTCGATTCCGTTTGTGATCATTCTGTTTAACGCCAGCAATGCATGT ++ +*+,&&$&'(&#'2.0)342),*(%%('*($%%&$%$*(*'$+('&$&&((%%13;A<:7*%$#$#$%&&%$)3/&0(+((*'/1(-($%#&%(*43-*',&()($%&%$'&%&(*#)),+$#%%'5>=@=9D?4+))-++8DFCDA4&&))%#*-*/44443..-&,+.01&+0###$$$()&#&+&&,&)&-%$#''*%%%26/0,,010:/%.<&<@AC<=A:96B;?==?1:)>8<33;?=+*#&'&-&'(()%%767150-%%($99;<@89-?5,,(7B3222110+,-+$3%%6655)%23+$$><>=838?<5.(399:7=3=@BBA?>@<632(*(,,0/()%%*()*$')(,'(%%)0*$%('5,1;5558:=9DCD?9;=8>62/*+*/1011091@@AGHH@CBEG&@EFACA9+*0094=?:878.*)')%&/,5:9+,-)/68==>9<6B6FH08DI?GEEHBJ@==,:<@=6:C>?@E?FEA=BBABIDC>?>66@.%87?AB7;=>CCEGCCEEB<,40-==CCG?%'%*&,&$,?EB>@CEC<0011.38;--3/2&'&%%%&%669ADD67;<,03=;3*%.<771=>BL<>:;:4*$.1&&3*5?BBDDCD=HA4,)0'%#%'-*)*0/>??G>:393258048@ABAAPNI@4B23CF:=IIM@))24B9>C?8:<>EC>?BB?ED9;@@B:<9>==@8EH93669=BF@?4%'%-2446=778@BF9?::CCI49CF?11=<:@CAEEHIJ@>?>--A2221A28A>9>=BGC-4;@AF11510;6@C73=;;0+('% +@SRR11410539.395798 395798/1 +CATTGTACTTCGTTCGGTTACGTATTGCTAAGGTTAAACGAACTGACTACAAACAAGAATCGACAGCACCTAGCACATCACTACGCAACTTTAGATACATTTCTTTATTTTAACAAAAGGTGCACAGCGCAGCTATTTCAAAAGTACTAAAGGAAACACAATTAAAGACTACACGTCTCTTTAGGTATTACTAAAGAACCAATAGAAATGCTTTGTGGAAATACAAATGATATAAGCAATTGTTATCCAGAAAAGGTACTAAAGTGTGAACATAAACTATCCACTGAATATGTGCTAAAAAGAAACATCATTAGTAAGATAAAATGTCAAGTACAAGTAAATAACAGAATAAACACCAGGTAAGAATGAGTAAACGGTGTTAAACAGAGAGTGAATGACATAAGGAATAGTAAAGTATTAAAGGCAACTACATGAGCTACCATTCACCAAGGTGCTCAGCCGATTCCGTTTGTAGTCGTCTGTTTTAACAACAACA ++ +%&03596?EF@?G*9$)*272/6658<<>()1/+/?B75''+%&9;@?<?E=9:A@DC<72245>?CB?EG:7;@/%78-:;BDAEBHJKBIEE>D@<;/07=;.(&2A7B>62:<8+:%$+&033/GIF76A::;AB8).5322+-(%(.>>,4F;9=AF=<>@D:OI6.8?,A&1A=@IQ7,>E>>=:16-45=00223;'<+,17;6+8?BHC==@B=BC4812-39FHB11DC>D960%844-6:::=963@AA>??@ADID?:BAAAH;5719)(;:98:8763D;718>=<**%*>=:==?(2,+'%%-377>AGD;C>GH7CAJ7;7@BC:=EI:=@5-,'#&%))(, +@SRR11410539.37919 37919/1 +CGGTAGCCGCTGATTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACCCGGAATCGACCTTTCCTAGGACTGGTATGATTTTGTAGAAAACCCAGATATATTACGTGCCAACTTAGGTGAACGTGTACGCCAAGCTTTGTTAAAACAGTACAATTCTGTAGTGCCATGCGAAATGCTGGTATTGTTGGTGTACTGACATTAGATAATCAAGATCTCAATGGTAACTAGCCTTGATTTCGGTGATTTCATACAAACCACGCCAGGTAGTGGAGTTCCTGTTGTAGATTCTTATTATTCATTGTTAATGCCTATATTAACCTTGACCAGGGCTTTAACTGCAGAGTCATGTTGACACTGACAACAAACCTTACATTAAGTGGGATTTGTTAAAATATGACTTCACGGAAGAGGTTAAAACTCTTTGACCGTTATTAGGTGCTGTCGATTCCGTTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAT ++ +($.'*#%%$$&$#(*&#)21%'(7138=>F668ENG?A41&&.%-1;:33458&=:/3:?=<56&.&&&+69A:EB=>8=CC@C@EHLJ@EHCGFNI?GB<>BF@:C<97966655-::;>7>?:;6><5;FIBEEDCB;4-()9,78>>-0:9784=99=>?CCEHIC59@30+*#&$$$,AABI*B:>=@@TLJA9@=@IKACA?BAC>=9:8C4=.0+CJE78<5JH>968>@@>AGBJE==>A66<.:<9:87A54EELOECB0@'::///,/-.?8@GJJ@FD688>?<887231../:?42-,/491>796,=;;KIAC?>;?<932=BC@87+427>;;@C@?644#%$ +@SRR11410539.2339655 2339655/1 +CAGTGTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCTAGCACACTCCAGCAACTGTTTGTGGACCTAAAAAGTCTACTAATTTGGTTAAAAACAAATGTGTCAATTTCAACTTCAATGGTTTAACAGGCACAAGGTGTTCTTACTGAGTCTAACAAAAGTTTCTGCCTTTCCAACAATTTGGCAGAACATTGCTGACACTACTGATGCTGTCCGTGATCCACAGACACTTGAGATTCTTGACATTACACCATATTCTTTTGGTGGTGTCGGTGTTATAACACCAGAGGAACAAATACTTCTAACCGGGTTGCTGTTCTTTATCAGGGTGTTAACTGCACAGAAGTCCCTGTTGCTATTCATGCAGATCAACTTACTCCTAGCAGCGTGTTTATTCTACGGGTTCTAATGTTTTTCAAACACATTGCAGGCTGTTTAATAGGGGCTGAGGTGCTGTCGATTCCGTTTGTGAGTCTGTCCTGTTTAAACGCTACAACGCCCGTACATCAGC ++ ++$$%(').46:9/3'/03($&'(),%();4BG=>:?@@?@:@@@>:;7HPO7,0/97C@D?A@BD?AHDILHG@>@?A@A@A;?+0+/@=9:**.@EEC@BEFC64*#)89:755,3;6.9:3.)1.*(07E:DED5=B:99AC=?=::C?=6:FFC@@5CIBDCB;+,?@HJBBJJIB+?<90/82:210%**2:DA>227.///;76677<1<9=<:770.7,,1/4/$%%$&02+/11157?%%-,*5%-2368;;//*-./3,%5757>>@F?@9=-=+;;09$,@HDCGHDEB@ECE529.;/2:,CEAC>@72,)5&/2?:;>296CC987&&)3088C@CC;@7;;<<%$=6:/,#%(,-:C@EEDEC>>8))&/BGA@?;?ACHCGD8CIIB;78'%(%+)+,/36=88>A>@:9D<:.?4=BEGCE91/*(-0%(&236')(&(/1)*((:;=CB>78/3('%#($%$%&'$%&&'%&&%$$ +@SRR11410539.2279760 2279760/1 +CAAGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACTGGAATCGACAGCACCTTGCCACAGTACGTCTACAAGCTGGTAATGCAACAGAAGTGCCACCAATTCAACTGTATTATCTTTCTGTGCTTTTGCTGTAGATGCTGCTAAAGCTTACAAAGATTATCTAGCTAGTGGGGGACAACCAATCACTAATTGTGTTAAGATGTTGTGTACACACACTGGTACTGGTCAGGCAATAACAGTTACACCGGAAGCCAATATGGATCAAGAATCCTTTGGTGGTGCATCGTGTTGTCTGTACTGCCGTTACTTACATAGATCATCCAAATCCTAAAGGATTTTTGGCAAAAGTAGTATGTTACAAATACCACAACTTGTGCTAATGACCCTGTGGGTTTTGCCAAAACACAGTCTGTACCGTCTGCCAGGGTATGTGGAAAGGTTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACTATAACAATACATAA ++ +1%%('*/0245D23,/03-//B8@B?@;.-6?MIFJB8>>??0/,73@8<6&%+-,355?91-@EC=?FI@=@6=7<>;<<<@=GA@@4;=8=DACDDB99:0/,,3@:;1((,HC8;B@?:@BFDF@79::<@93.;:9?@GF44==9<9@DBBFDE=DIB>994*550$0638*9?=,C<04).)+-.?@DF66==95AC3DAA==+.95B=C@B>00837:=>=BBFC3=7625(/55344-78=?6/>&)'8A33<3CEDCFG629299:>D9889C/%%%%-.:5C5:;>?..B;=>$$);?A(550=@>6-,++-.(&%'(%&0$$+27:AB5-,7(0<67559?DD<9/$$&67424@A;;=@??A>>@<:?B408/644)/$$967--&0AIB9AA??@?=>@=<=7:;DCCA?7<>=A;>D@601%%()**21,'&-%'%% +@SRR11410539.745498 745498/1 +CGGTATTGCTTCGATTTCAGTTGCATATTGCTAAAGTTGAAGCAGACGACTACAAACAGAATCGACGGCACGCAGCATGTTGTGCCAACCACCGCGAATTTACTTGTTCCCAGTACTACAGTAGCTCCTCTAGTGGCGGCTATTGATTTCAATAATTTTGATGAAACTGTCTATTGGTCATAGTACTACAAGATGAGACACCAGCTACGGTGCGGTCTATTCTTTGCACTAATGGCATACTTAAGATTCATTTGAGTTATAGTAAGGATGACATTACGTTTTGTATGTCACGAAAAGTGCGCTTGATCCTCAACTCATTGAATCATAATAAAGTCTAGCCTTACCCCATTTATTAAATGGAAAACCAGCTGATTTGTCTAGGTTGTTGACGATGACTTGGTTAGCATTAATACAGCCACCATCGTAACAATCAAAGTACTATCAACAGGTGCTGTCGATTCGTTGTAAGTCGTCTGTTTAACCTTAGCCAATATTTATA ++ +-$$&$#%%))+(%$)-0+.124,42557=>><76*721*/6,;697+3&860/78+3234==8<9=$,5/%$*%)2-,+A>*@CCACICFMMI@B;C=;-,(1%%')(%.,;6'*35;=<934-<;;//<23%%$'+5=<1121%$#&(&&2'&&/,.''(+,1()'26<=D==@FB;4+-0((06)*,,($(-2*>@;A>D88856,+790(/=?AB:H?=@:GHD:9979-$*-2>GFEEIE63.-*-F?;?=8:9AC@?CFCB;;CMGCUF:>?@<;GFFFEFGF::7<9><=925+)387A66=;;74BBE@BI*64;<(&)(1=A?;@?A<>>00./0//(&-11+)#$%$## +@SRR11410539.2282109 2282109/1 +CGGTGTACTTTGTTCCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGAAACGGAATCGACAGCACCTGAAATCTGGCAAAGCACAGAAAGATAATACAGTTGAATTGGCAGGCACTTCTGTTTGCGTACCAGCTTGTGAGCGTACTGTGGCAGCTAAACTACCAAGTACCATACCTCTATTTAGGTTGTTTAATCCTTTAATAAAGTATAAATACTTCACTTTAGGACCTTTAGGTGTCTGTAACAAACCTACAAGGTGGTTCCAGTTCTGTATAGATAGTACCAGTTCCATCACTCTTAGGGAGTCTAGCCCATTTCAAATCCTGTAAATCGGATAACAGTGAAGTACAAGCCTACCTCCCTTTGTTGTGTTGTAGTAAGCTAACGCATTATTATGGTGCAAGCAGTTTGTGTAGTACCGGCAGCACAAGAT ++ +-%&*$*'12379><-/14ABCBBDMACAC9==6INIFICC=>A:A;9=93%'$31.2%)-2<>@9-(;=<=;*$'&2()&),6@BC7:DC<:<438DA=DC:=(+%/-00'&&&)/2+,+9:?879)3(-.;,9/FGA@;047;<8A><<>;A>;@ACBEB:85?75CB@CFJCH>?@@@;>?:D4DG@B@9913::=>37345/0)7==?B=9=55=61633=>A=>;9:8?CEDE=529*;:5&/8/;=EEI9CE9?;;6++-@???DC;C=A@?A@/(-+-2//01489$('-.)/2;=CDFE;BD:=>BAA<9;A::F>@7856;-,-('))++.**+..-,23CDI:?CLCDIKKL>A=DC9=?AAHCADBA?=+%/5<<@+)-BC8EF4=227-2/,626<;?L<@><9=>?668DF;(-/38./*EK8<=9?DF=2311:>DCE8>=9<61/17C=,-->?>>=>881>>??+?)>@EB<@ACC??D35'58;;9?:=6+*2:0.0*6845933,#$%&%)+663:3*8%%21;*''&&"#%'+2B??5CEFBAD>;B9:90,,'%$&%%#%(((&117<943*)& +@SRR11410539.2307189 2307189/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGGTGAAGCTACAAGCAGATCAACTAACACCTGTGAATATCATCCATGTCCTTCCCTCAGTCAGCACCTCATGGTGTAGTCTTCTTGCATGTGACTTATGTCCCTGCACAAGAAAGAACTTCACAACTGCTCCTGCCATTTGTCATGATGGAAAACACACTTTCCTCGTGAAGGTGTCTTTGTTTCAAATGGCACACACTGGTTTTGTAACACAAAGGAATTTTATGAACCACAAATCATTACTACAGACAACACATTTGTGTCTGGTAGCTGTGATGTTGTAATAGGAATTGTCAACAACACAGTTTATGATCCCTTTGCAACCTGAATTAGACTCATTCAGGAGGAGTTAGATAAATATTTTAAGAATCATACATCACCAGATGTTGATTTGAGTGACATCTCTGGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACCCAATACGTAACT ++ +%.0+4.23712?42.9><:=;BGEH2-A5631//9:40*/))*')(*)&'#$&((%-(($%%%##$))))%$(%%-3296%%'(&%%,./:<<>0A@=8=6?DD?>=<21,./(/009:HA=C;)9>?BA<<@C@<==77:552*+2'()03@'50'(/(+33.)4($+31>CHEC>CH9470@@=><>4><'.;9=EA?@HCABD9?>9@;<69?A@;**7:9>5DC*.9;9=<92**('%()%+04;:?;:=69:>474.+3448.359<6<=6:432+1%%++15;?<9:><=<,++556AD=9@./90-+7)&<;<;6?@823=//772701>@DA@==;;;C?B@CA<.*>&,710AF=B9DDEGE;?863.#$%&&)9%'3=;;:6666@9CF:8CBGF2%$2:;*8B?DAFC;;2928?19873?EEHA;==DD?3;;?<@=9:A=49ABB@>HI53))*++114..'*%# +@SRR11410539.2200529 2200529/1 +CGTTATACTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGGAATTACTTGTGTATGCTGACCCTGCTATGCACGCTGCTTCTGGTAATCTATTACTAGATAAACGCACTACGTGCTTTTCAGTAGCTGCACTTACTAACAATGTTGCTTTTTCAAACTGTCAAACCCGGTAATTTTAACAAAGACTTCTATGACTTTGCTGTGTCTAAGGGTTTCTTTAAGGAAGGAAGTTCTGTTGAATTAAAACATCTTCTTTGCTCAGGATTAAGTATGCTGCTATCAGCGATTATGACTACTATCGTTATAATCTACCAACAATGTGTGATATCAGACAACTACTATTTGTAGTTGAAGTTGTTGATAAGTACTTTGATTGTTACGATGGTGGCTGTATTAATGCTAACCAAGTCATCGTCGGTTTGTCGATTCCGTTTGTAAGTCGTCTGTTTAACCTTAGCAACGTAAC ++ +#%$$%,,238<>O860@9=A68464667*=*EDBFI;=9@:=>=AEHAFF5:$'#):==<(?&;@AA>6=EBD==6;<>@79=@3)3;FCHHNKEE=7+*,-056DB;=8:%%*:@A?FCAED;=<:;FBEF=*)((8;A>;@FH=<@;;7<><==?-223<<55357CFD;;&,$7:8244021310,-%9;=>ABP:17:BBBB@?>)-;'(43-8AD9IH7%&;:8A'.54-@-7-9CEBBA=<77//.$%$$8A?@B?42:>=9@<9C=@CGFDE88>7FC??ADE76/6431=:69''4.569AC89<@=CA=@AH==6-B;?:DD?;B??=618??@C::@$<@87;=IEFB>?=:<7?=>>?;++;BIEBD161320756/+644)9;FD>?;;;:@CC>8<<7;A<><30,$#%+:84=@E??>=@:.---0834,((+..>@JIEDDDCCCEKFB=98:600'89=ED@=;887622/004388?@A;<9,798>DDFFC=78?>ID?-=/0>@8(=%0*778AB>A79+(.;**&)*5=;:.-815,,7++%87ADC56558/928?:;>=4911**//2'&,-.?=;<<=A:B:99,()#$,'*-25==AD<<@CB591B/C@;;G:=>9;.;,0%:9<9);FGG?FB993<<;-->@3?;9C33BADBCHED?A>/(/,3>@DEA@59>B>?>;=9BBE33@><@;:?7@78444987;?8;BA<<72884'* +@SRR11410539.1427267 1427267/1 +CAGTATTGCTTGGATAGTTACGTATTGCTAAGGTTAAACAGACAGCTACAAACGAATCGACAGCCACCTCATGGCTGCATCACGGTCAAATTCAGGTGTAGCCATTAAAGACTTTACTTTAACTTTTTTAGAACAACTTCAGAATGCTATTAGCAACAGCCTGCTTTCTCGCTTCTGAGCAGTAACAAAAACTGCATATGATGGAAGGAACTAAACTCTGAGGCTAGCTGTAGGTTGCCCTGTTGTCCAACATTCTTCACATAAGCTTGTTTATGTCCTAGCACCCTGCATGGAAAGCAAGCAGAAAGTAATTGAAACCATTTTTTCAAAGGCTGGTATCTTTAGCGAAAGAGAATGTCATTAACTGGACACATTGAGCCACAATTTAGATGATGATTCTATGAGTTGTTGTTGCAAAACTGAAATCAGACTACTGATGTGTGCCAAGGTGCTGTCATTCCGTTTGATCGTCTGTTATGTTTTGTA ++ +)$(&%$($'''(+&$#%%+(-$%$$)),-%&,==4,-+&%'(&#$#&28=>:,%$14..''%)),(34;<*-)*$%#,5:>4CA>6C8;=B+.(1)0'#($$$-1012,*,$$+&$#$&$))/7:G@8,6&*A?99=>404,-0,%$%*,.2(1(''$&))&$$$%*-&$$$%'%$&%*-('-''$1:<3%/969687>?>:,-&(13++,--/.:=<;<74,%)%$#%%(--/:<;AAFB><=0('.$$*),/(++$%%%&)),+,.0?@93*''#$''245772'4:6./369/'%')#*,),/954&&&(.+..38;:1(()().%.(.)14788&&'&'25;=:;54+++*&...'(9=9BA=9?A>?>87A@<8,&**8;>>;<&>B;?>?;593-,*%$#$'$#++16<;B1$9A<$;56*/-+*,$&&&&)+.354(&&(*)&($%&(%$#$%%%#$# +@SRR11410539.1664447 1664447/1 +CATTGTACTTCGTTCAGTTACGTGTGTGCTAAGGTTAAACAGACGACTAAAACGGAATCGACAGCACCTCCAGCAACTGTTTGTGGACCTAAAGAAGTCTACTAATTTGGTTAAAAACAAATGTGTCAATTTCAACTTCAATGGTTTTAACAGGCACAGGTGCTTACTGAGTCTAACAAAAAAGTTTCTGCCTTTCCAACAATTTGGCAGAGACATTGCTGATACTACTGATGCTGTCCGTGATCCACAGACACTTGAGATTCTTGACATTACACCATGTTCTTTTGGTGGTGTCAGTGTTATAACACCAGGAACAAATACTTCCTAACCGGGTTGCTGTTCTTTATCAGGGTGTTAACTGCACAGAAGTCCCTGTTGCTATTCATGCAGATCAACTTACTCCTACTTGGCGTGTTTATTCTACAGGTTCTAATGTTTTTCAAACACGTGCAGGCTGTTTAATAGGGGCTGAGGTGCTGTCGATTCCGGATAGTCATCTGTTCTTTTTAACTAAGCAATACGTAAC ++ +'%&&*0+-.023DA@:@?7*0,*&$%.9@=9:1E88;='2040<:6449:7%935277633)+$%**-.7>E<9+,;=B?<<::AB@;=9-.%$)'':6;9=>=957230<4607:::510/>;?><9;;=A.(&-'&'(&,./)',-'#%'3382DAA?<=4454./12348++++;<<887:69;EDAJFFFA99=C@C=>>=B@?>F=DB69==@9,'82<=;.9;>..@C@6@2>:;789966311$%;:=9?$(?AHAEDA?>>EA@1-7/<=;AB?@0/.=+E@@@>1'/;=>AB?C?EB:3?23=>>B@>%*/;9:;34:;E=48@;::@;?568?=<>;7;>55'*%(%'14.664.40&&'''&**''%'$,320%$%&((( +@SRR11410539.819470 819470/1 +GTGACCAACTACGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTGCAAACAGGATCGACAGCACCTTACGACAGATGTCTTATTGCTGTCGGTACTACTAAACTGCTTGCACTGACAATGCGTTAGCTTACTACAACACAACAAAGGGAGGTAGGTTTGTACTTGCACTGTTATCCGATTTACAGGATTTGAAATGGGCTAAATTCCTAAGAGTGATGGAACTGGTACTATCTATACAGAACTGGAACCACCTTGTGGGTTTTGTTACAGACACCTAAAGGTCCTAAAGTGAAATTATTTATACTTTATTAAAAGGATTAAACAACCTAAATAGAGGTATGGTACTTGGTAGTTTAGCTGCCACAGTACGTCTACAAACTGGTAATGCAACAGAAGTGCCTGCCAATTCAACTGTATTATCTTTCTGTGCTTTTGCTGTAGATGCTGCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATGTAGCA ++ +%'%##$###%#*1;<.(-2-$76//&&%/5'(1BFEDG>:8;9<87+-&-13.)%&%',.00-**))))(((29<>:CAA89;F5**-2/1+#&'*)&:22%%;?A?D;8@@--=>=3/>@DA8???.$.--5<<9;>44477<<387&.526272/9=CDA9:7455*'*/0'/)&))/((2:3&&&66+,/,'2415*+*/3'*(9:-.8>@&)4=;:>+.986>;><797-+9/00,+-,.38;*354765&,@FFM?2&)'',8>?4.))%)''.1132+,+,146=@?BB.&)94=9@A5?45D=BILC6920/2><>?23/44DF>C:<>?7?31+07<<2->,&568)38(&67<=>=,-/A+.-?GEAABB7@@@>6>2/654.:(+?<:>?CED;H?9:;;;46826;5;H@DE::;@8:G>98:8=BDGC?B;FED.*..7>8=9D;>?5$%,,--&+,*)$&$&$&# +@SRR11410539.56894 56894/1 +CATTTATTACTTCGTTGATTGCATGTAAGTTAAACAGACGACTACAACAGATCGACAGCACCTACAGGTTCATCTAAGTGTGTGTGTTCTGTTATTGATTTATTATGATGATTTTGTTGAAATAATAAATCCAAGATTTTATCTGTAGTTTCTAAGGTTGTCAAAGTATTCATGACCTCACGAAATTTCATTTATGCTTTGGTGTAAAGATGGCCATGTAGAAACATTTACCAAAATTACAATCTAGTCAAACGTGGCAACCGGGTGTTGCTATGCCTAATCTTTACAAAATGCAAAGAATGCTATTGAAATTGACCTTCAAAATTATGGTGATAGTGCAGCATTACCTAAAGGCATAATGATGAATGTCGCAAAATATACTCAACTGTGTCAATATTTAAACACATTAACATTAGCTATTACCTATAATATGAGTTATACATTTGGTGCTGGTTCTGATAAAGGAGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACATGTAATACCATCAAC ++ +/1782..1)332'%)+**27-1(&$(%&420.2-44469?@>='++)''&67;>@KJA@8A>792,)2,441?BEFGCGFAHE?:;<;59>?:32)68>9>FDADA674.-89:696877=::>-$&<35>B5:BB@@AC?=?;CCH>?@DFEL92ED?@@2>0=;(;5?A1&%&-,/+,1-440(:($%,,)*'*&95;?881>*,+C3A<(#(.3-3*55:88><3*33530))6??*+*2,-1.+*/'',,$)*)57698KO>85:32$&/:6>>A@D;>;3@=>GHNH>BEGDHEHGDFFH11.0&&'%$&&1*2?=;>A?@?&+(0340=<=<5*+;,+79;DEDBFC>>@$524.0,%6%37-(2'%(-)28?A>/5()8;64@:4><71/0'%&%0021$($'()(% +@SRR11410539.1549846 1549846/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTATTTAAACGGAATCGACAGCACCTATACAAGCACCAAGGTCACGGGGTGTCCATGTGTTTTCAACTTTGTTATAGGTGAGCATATAGTTATTACAACTATCGCCAGTAACTTCTATGTCAGATTGATGTGACAATTTAAGACATTCAACAACATCTTTAGTTTCTACATCTGAATCCAACAAACCCTTGCCGAGCTGCTGAAATAAAAGTAGATAAGACATTGTCTAAGGACACATTCTTTGCAAGTTCGCTTCTGCAGTTGCAACTAGTGTTTTGAGTTTTTCCATTGGTACGTTAAAGAAGTTGATGAAAACGTATTAACGTAAGCATCAAGCATTTTAACTGCAACTTCCGCACTATCACCAACATCAGACACTAATGCCTGATCTAGTAACAGTATAGGTTGACACATAAGCTGATAGCGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTGTAATACCTTCAAC ++ +-+./2>9<=>967.=3>?B9@A@?<>?B?==,CKH@B-60205<:83*&&(359:/2(07=AA867:>BAIGEIB??8BGKE=:-943-=)/@9==''4%,-(0;=G>?>?;ADD@?@A;)::912*5:AAABDC@663+:4549A:=FFEBDB40-;=CBH:@=@?=AEEDC:9JGI=EF@FE=BIH?>>DGAEPF?AAGFB:=CCB>CAA:A%%=**9FG?HBCGG896=BLBHFEG@DL@=EGBA?C5267;3?CI:C?A=>AJGA8=@A@;+&+33578:;5>4734++;?DAFD?=>:=DDED79B;;ABE@;8<88+6;99;2&)??588/-GJBE;>@ADI@D78;:;><67$$A;B>G?C;<;7734=>A:=@;<0*/7>=00:?AGI@A>@:89+%$(#+)%&$(9724@>ABDFB:9367E8BD?8;3,&*?AB>**&&$'+,6642&,%%#%&$ +@SRR11410539.2008465 2008465/1 +CGGTAATACTTCCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTAAACGGAATCGACAACACCTCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGAGCACGTCAACATCTTAAAGATGGCACTTGGCTTAGTAAAAGTTGAAAAAGGCGTTTGCCTCAGCGAGACAGCCCTATGTGTTCATCAAACGTTCGGATGCTCGAACTGCACCTCATGGTCATGTTATGGTTGAGCTGGTAGCAGACTCCGAAGGCATTCAGTACGGTCGTAGTGGTGAGACACTTGGTGTCGCGGCTCCCTCATGTGGGCGAAATACCAGTGGCTTACCGCAAGGTTCTTCTTCGTAAGAACGGTAAATAAGGAAGCTGGTGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGATCCTGCTGGTGCTGTCGATTCCGTTTGTAGTCGTCCTGTTTAACCTTAACTTAATACGTA ++ +/&()((*8674%(A@<;478<3>=<>',>??<=7EA@<>'1*+01=50,671//2072?@E@'(;DC?@C3?@;AGNLHEFAE;7H@AB;496-(;--%%%&.-+%2009:=DCAB0,26:6:??9525,,7<3B?=B22A?:?>9DE@>=C162(&&&(-,,,-34**&$2$);5521$*??BG@1,002.7%'&%%)*6%;668?928AJJFA9A?C=>@B$&&176-2<3&=946669:6/*3))+.7>9?=<.@<869;F?320:66>=8;@AEDGB;<=5<43)7>@?A<;&',.49$*212*130*9CCDCB=AA>>@>?562184B999+*)4/15524;@686;?))1('))&(/%(/*(9<>@A=**.D;98A>>=B?>%%%%%?B@A<:*. +@SRR11410539.105820 105820/1 +CAAGTGCACTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAGCAGTCGGCAGCACCTAATTTGGAAGAAGCTGCTCGGTATATGAGATCTCTCAAAGTGCCAGCTACAGTTTCTGTTTCTTCACCTGATGCTGTTACAGCGTATAATGGTTATCTTACTTCTTCTTCTAAAACACCTGAAGAACATTTTATTGAAACCATCTCACTTGCTGGTTCCTATAAAGATTGGTCCTATTCTGGACAATCTACACAACTAGGTATAGAATTTCTTAAGAGGTGATAAAGTGTATATTACACTAGTAATCCTACCACATTCCACCTAGATGGTGAAGTTATCACCTTTGACAATCTTAAAGACACTTCTTTCTTTGAGAGAAGTGAGGACTATTAAGGTGTTTACAACAGTAGACAACATTAACCTCCACATAAGATTGTGAGGTGTACTTAATGGTGTTGTAGTCGTCTGTTTATATATATGCAATATTT ++ +-&'$$%$%.56:?F6=7>@C?.'A8@A:=+2&?IHHK@92527==<=;:;;(,%$/6$&,')+,,)0:>;<=4655<$;B=>>?9@>:>@IJIDJECBACA?G1-@8=>>@CEFJ@JCB?8%*7BHEBIJCDDBAICEFCFCHF9>HE@;?B?:::<=E7/=>FA:=C@>A??;832+.9BABCM8,,124978:AAB?>6122//851BB::BC?<;8;?;<<>2247:??@>:<82?@@BCCDJD55@;E5?@A,<&6<::9=9=32=/@??@C7HLB>;8D@>?==>A67:2,764;866/3?A@IAADA47786/+)/-13;9:9:61-853,+(023$3A;A;;<9@CD8EEA?=.:<<;>;=D=HC@FKDC;EIEE@?9;6883389++#,*%(/2,245(.%'& +@SRR11410539.1167057 1167057/1 +CGGTGTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGTCCAACTTAGGGTCAATTTCTGTACAAACAACACCATCAATTTATAAGTAACTGGTTTTATGGTTGTTGTGCCCGGCTTTGTTTTCTTTGTAGAAAACATCCGTAATAGGACCTTTGTATTCTGAGGACTTTGTAAGTAAAGCTTTTTCGTCTATGCAAACCTACAAAGTTTCTTTAAGGATTATATGTTTATAGTGACCACATGGTAATTACCAGTGTACTCACTAACAAGTAAATGTACCATGCTTAAGTTCAGCCACTTCCAGGCAGGTGGTGCTGACATCATAACAAAAGGTGACTCCTGTTGTACCTAGATATTTTGTAGCTTGTTTACCACACATTACAAGGTATCTGAACACCTTTCTTAAATTGTTCATAAGAAAGTGTGCCCATGTACATAACAGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACATGTC ++ +*#%%%)$7<;>;JF405<7/4221224)0-./A<;AC;69@B?@:8/*9DB?4588?>>9D>KBLA>/0--:<:>?@MHNC?B-/01/56-2'%%%#&$%'&$','),6:='''25:K>@B:<>::>>51776&*&(14==>2>-5+JKJ98*++8453'110../56::/)(#$$%#%$&#%')$,7;?;<::-()725:676.%88;6D50,/.2'#)&'--0,5;=A773('''--))*((.64+-$$%'%%'#%&/442119''&('*,.//*:*<:=8@>>+'5<2/+/%53;BB7+*/$653@;7=:C@1,(.56898<;=87(+12$$+18-.28<:69<=<>>8((((*-24,/019;A6558/0/;51;CCA@@?4??C?+=5A;<=9?4/:5A:8B;88;:CB=>7:893.43662664455.+,*/*+%##%&%%))(&%$ +@SRR11410539.635065 635065/1 +GTTATTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTAAACAGGAATCGACAGCACCTAGCAGCATCTGGCAAAAGCACAGAAAGATAATACAGTTGAATTGCTTAGGCACTTCTGTTGCATTACCAGCTTGTAGACGTACTGTGGCAGCTAACTACCAAGTACCATACCTCTATTTAGGTTGTTTAATCCTTTAATAAAGTATAAATACTTCACTTTAGGACCTTTAGGTGTGTCTGTAACAAACCACAAGGTGGTTCCAGTTCTGTATAGATAGTACCAGTTCCATCACTCTTAGGGGATCTAGCCCATTTCAAATCCTGTAAATCGGATAACAGTGCAAGTACAAACCTCCCTTTGTTGTGTTGTAGTAAGCTAACACGTTATCATCAGTGCAAGCAGTTTGTGTAGTACCGGCAGCACAAGACATCTGTCGTAAGGTGCTGTCGATTCCGTTTATCTGTTTAACCTGTAATACATCTT ++ +$$'('+)44=@?H6>;?FFA?:CADA8=.==0:FFFI>><;>3;/*(268,&;<,5>AAE=GGHFBB7230*'(626)$)8GHH>IEI9=6AEA)FG>?IG?:BB84,,+2*$$$''8>D@A@B@9;28/000-99AA@898E@A?2--;9@CECDGD9A?DC?<3>@A49389?35>3:;;>:'1--045)-,77<=(9>79A:#%%%4100303;118/5-2-99>0347''2.7<98*+)2**(*&+&);>43;@:?=9C@ECA7===@732676?>?>73/-8:<;9;+8?<>FBB=<6657))1AFB8<%<;=>;?4;07@9??BCJAGFDTG668CF@FE@BE6FJDGG?@FAGB@@3,?455?8:BB<@G733?::7CD1>@C6+;>AC<=LI@?DFH>DC66:=>D=>856CC<6736865>=E01=1;>7:7*-+()33=<@;>=3/%8=@F=--+=@;:9BGHBCDG>JHLQF<93B?AEG9%%%?EC9,)$%&*)-3>@FBGC876/5;1*'',/38887%&766>EA77<84/8ADB?>=>C22&%'26B:8:>F=IHD@BA><>34=:7::9>:==>;=5/.75?=?CC@=>776=B09;B?A>7FHCGG9%%4>DCA::<BFBCA?&88844;AAH.@>@CGAA=@>DFD;;:BC@&,397=?<>68@;92+*($&%$&)$%%&)% +@SRR11410539.1857886 1857886/1 +GTTATGCACTTTCGTTCAGTTACGTATTACTAAAGGTTAAACAGACGACTACAAAACGGAATCGACAGCACCTGGCACATGGCTTTGAGTTGACATCTATGAAGTATTTTGTGAAAATAGGACCTAGGCGCACCTGTTGTCTGCTACTGATATAGACGTGCCACATGCTTTTCCACTGCTTCGAACCACTTATGCCTGTTGGCATCATTCTATTAGTTGATTACGTCTATAATCCGTTTTATGATTGATGTTCAACAATGGGGTTTTACAGGTAACCTACAAAGCAACCATGATCTGTATTGTCAAGTCCGTGAGTGTGCACATGTAGCTGAATTGTGATGCAATCATGACTAGGTGTCTAGCTATCCTGATGCTTTATTAAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTGTAGAAAGGTTGTAGGTGCTGTCGATTCCGTTGTAGTCGTCTGTCTTTGGCTATAAGCAATACGTAAC ++ +'&(0-,&&&(+,+0/-%$'4<0*%%%('#)-89''36;=@D@<<>684-/-5332287;)3:<>E94:@89=82,%&103-2&&,589;EIFEE57:0(*%&''67>>><&%56;?E922,;0/*%)2)-0043:8571762+-+%$%,//,(+-,1&2%,/'7466;=AHC36?ADB;=-)($%#'&&13=29BAI2;=.51:=B=?/?-2(+%:.0:867.758??:@AF@EF>@?D3,*776EFDJ;HAC>?@--+*,-?EGI;624129:>BAD=?46003++/-(())5;9'((:<(6=**0$$/&&#$%*%40,,81//.6/52.,-)+).**<0@>>7900+(-,&*5?.)-.A:32.&&0/19;CED>>A@C2;667*2:071/5>3-($)&%?=?=3.@==GI;>9B@36655+56<4-'&')*)'#&%.&)&+&(&$*('&%$ +@SRR11410539.920390 920390/1 +GATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCAGTACGTTTTGCCGAGGCTTCTTAGAAGCCTCAGCAGCGGAAATTTCTTAGTGACAGTTTGGCCTTGTTGTTGTTGGCCTTTACCAGACATTTTGCTCTCAAGCTGGTTCAATCTGTCAAACAGCAACAAAGCAAAGAGCAACATCACCGCCATTGCCAGCCATTCTAGCAGGAGAAGTTCCCCTACTGCTGCCTGGAGTTGAATTTCTTGAACTGTTGCGACTACGTGATGAGGAACGAGAAGGAAGCGACTGCCGCCTCTGCTCCCTTCTGCGTAGAAGCCTTTTGGCAATGTTGTTCCTTGAGGAAGTTGTAGCACGATTGCAGCATTGTTAGCAGGATTGCGGGTGCCAATGTGATCTTTTGGTGTATTCAAGAGCTCCCTCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACATAGCAATACGTAGC ++ +'$&%('56999@@99CCCBC;?>33>DHEKOH@99A5B@77<>@DC@?AFG=9<;1D.DD58?8/3D@@@KGPA3.$..2+%/:338-2:>IH.CG>=>;>;@?C82100+$835;GG@A=?9>9:?:956=/73<>AA:35;:%-%6=%%<>?;26@?+78>&&..<;8688@I0B(F75<5@B?C;><:-7977%(5426=>;=@>>A>:A?.9BEEDB@CE8I5=66997666>?BFG79GH9EC?B?@A5AA78;8=4./....:,+-31+-024;2@01A:78::6:?A=@@<:89:?9;@<7?==?=@:72+)%*.-44;9327&$%&( +@SRR11410539.2170521 2170521/1 +CACGTGCTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACACAGACCATTCCAGTAGCAGTGACAATATTGCTTTGCTTGTACAGTAAGTGAGGCAACAGATGTTTCATCTCGTTGACTTTCAGGTTACTATAGCAGAGATATTACTAATGAGTATTATGAGGACTTTTAAAGTTTCCATTTGGAATCTTGATTACATCATAAACCTCATAAATTAAAAATTTATCTAAGTCACTAACTGAGAATAAATATTCTCAATTAGATGAAGAGCAACCAATGGAGATTGATTAAACGAACATGAAAATTATTCTTTCTTGGCACTGATATACTCGCTACTTGCTGAGCTTTATCACTACCAAAGAGTGTGTTAGAGGTACAACAGTACTTTTAAAAAGAACCTTGCTCTTCTGGAACATACGAGGGCAATTCACCATTTCAAGGTGCTAGATTCAGTTTAGCAGTCAATGTATTTGAAACGCCTTAACTCTGTGGC ++ +,$&%'$7:A=;D-+%;;?:E?EDBB'%.%8<007:)8@;CCCAB:B;DC=C@?AC<;;@BH?/:?ACEDCA?8@?(-33FE@6-0EGDB>/))A=16<>F@;EG?=DB@>><=5*$%')213@C@HC@EGDD82@46COD@@CIJ5.'-&16.+66;60+/'92:;::>7'/&)&&$(=4<@=+10@DD>GJC9>>2104D?CABDL?C=<:>B1.'%*24?;;:7;<578>?56,)&03-2412>CJD=>B899>?A:>E;59:;'8A@=@ADEFCC=DFFHF@AE9>53(($@A?;8DDB@AF@D>DIGREDF9B<<)&57%'8?65:;=>?FC:83541>D=?A?1.))'9;0/77///%$22.3ABC?@9B>AEHEDEA,(?GF?BDE8?20-@C@B56/<,84<>>>3==6'%'+*))/19?@?GD@(AADD@D?@:=85CBABA@?@B>>ADF>?++367&&&$$'1')&.,1-%$%()&.#$%$#$%&&$%%#%$%&$$#$')&$%'#$# +@SRR11410539.2162857 2162857/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGATTAATAGACGACTACAAACGGAATCGACAACTTCTCCATGGCAGATTCCAACATTACTAATACCGTTGAAGAGCTTAAAAAGCTCATGAACAATGGAACCTAGTAATAGGTTTCCTATTCCTTACATGGATTTGTCAACTGCAATTTGCCTATGCCAACAGGAATAGGTTTTTGTATATAATTAAGTTAATTTTCCTTTGGCTGTTATGGCCAGTAACTTTAGCTTGTTTTGTGCTTGCTGCTGTTTACAAATCAAATTGGATCACCGATTGGAATTTGCTATCGCAATGGCTTGTCTTGTAGGCTTGATGTGGCTCAGCTACTTCGACTTCTTTCAGACTGTTGCGCGTACGCGTTCCATGTGGTCATTCAATCCCAGAAACTAACATTCTTCTCAACGTGCCACTCCATGGCACTATTCTGACCAAAGGTGCTGTCGATTCCGTTTGTAGTCTGTTTAACCTTAGCAATGAC ++ +#-0187;=??:E?;4@DBD812(23.05)*3)&'$$'-//2CF@@FCBD9:$&,/('%%'*)$%&&(%358449**>BH>E0'$$)+$&.$$:<:C:C?::;01$//0BC85508-8(6;9;7875',51;673:@?@795@GB4+-;9=@5622=:ED>@39CB3./&(,3*3585@><334688>82/670/(,--/34B=56)6<>87C:?AAC@,#)&*&%%-003=E>>G:7@))BCG>BEOL@<=E>24--,566DCIED7:=+8:7:73$$(./(+.158::A<=@;?@AB:2611641/84=517;44+:<A5*)(-376:@A8961269AAC=888.?&6511782-+)+34<898<:66B9((8:9=A=CIFB8746448-,0$($&%$$$-,,16<.4))%(')/(*)04=974..0/)()-7607412*+-()+,0),:23%)2>?86;024;>572,,-$%>;;;>=69662%,*++++'&(($'''&&'88-,4,-/000,+3/7:=&-@14*2?7433-::3687<7<;8&')5251.<32.,'$&$'$%%%$%#$#$ +@SRR11410539.151547 151547/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTAGTAGTCCTGGGAGAATAAACACCAATAGTAGATATATGTGCTGGAGCATCTCTTTGTAGTCCCAGATCACAGTATTAACAGCCCAATGTCCACACCCAAATTATTGAGTATTTTCACACTCTGGTACTGGTTTAATGTTGCGCTTAGGCCCAAAGCTCAAATGCTACATTAACAGGTAATGTTTATTTTCAAACAATTCTACATCAACACCATCAACTTTTGTGTAAACAGTGTTATTAATGATAGAAACTGGTGCGCTCACCCTGTTGTGTCAAAATGTATATTTACAGCGTAAATGACTTTCTGTTTCAAATTACTTGTAAAAGTGTTCCAGAGGTTATAAGTATCAAATTGTTTGTAAACCCACAAGCTAAAGCCAGCAGGTGCTGTCGATTCCGTTTAGCCAGTCGTCTGTTTAACCTTAGCAATACGTA ++ +&-.45378:<8G70+7GE@<:><=:9842-(#&%+,''-*$&,1(%&&(,./403::?>?;;;E3@/-;AC?JKDBG8:FE1:-**--+)+++45((E/=78:8:>ECBCFA2865<;87:>?>/@:D?K0@=?7@??B;:=HGIKDG?-0**+(&#.*'((()/%$$%-(-;<8?5<>%%#(('(%$$#$&&%$$$##$#$#)#$#&&%"$%'&&$##&%$&$$&%&.34368B>=EE:;+1A1,,DE74ECFDJ?9@9=GIHAEELC:D;=DCDEUI>JBF77>60A?=9@<>ADED57938661()%%%'123>;11=6-- +@SRR11410539.590637 590637/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAAACGGAATCGACAGCACCTTGTTGACTGACTTAACAAAGCCTTACATTAGTGGGATTTGTTAAAATATGACTTCACGGAAGAGAGGTTAAAACTCTTTGACCGTTATTTTAAATATTGGGATCAGACATACCACCCAAATTGTGTTAACTGTTTGGATGACAGATGCATTCTGCATTGTGCAAGCTTTAATGTTTTATTCTCTACAGTGTTCCCACTTACAAGTTTTGGACCACTAGTGAAAAATATTTGTTGATGGTGTTCCATTGTAGTTTCAACTGGATACCACTTCAGAGAAACTAGGTGTTGTACATAATCAGGATGTAAAGCTTACATAGCTCTAGACTTAGTTTTAGATTACTTGTGTATGCTGCTGACCCTGCTATGCGCTGCTTCTGGTAATCTAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACCTTCCCATG ++ +)&#$398;<===OB:35;;;<5A>:987-.)DGFDF?301259:<>96=>;94%''%54;=959:@>ADG<::3&$*?@CIF<==JH;19864$''()'*<:?I=GHJDAC<>=;80'.01378+2>>8E7')5>B8<123=?>@=98=A984>>?JHMA;=C@A><),<9.567:7>:956===@E@99B-?4;89;;??FGK:=@A@BAD@B%?CCEDB<:?114+E==$&%3333:<6;A?MH/344:<8:>CD2A28:75:@@?8?FHC-...,/0+1)6459:AB>AA?@@>?=@-)?@D@?=:..017-/$$&>7==<:/&''(+98,7-/%'&++).7?@;;;7+';<,)..+/,66'450)'*-093/+18:D?@>?A>:=44*%(+(-D:BC1,>4BHEC45-=34,)-&),4;8:59IG9*871A5DFEDB>98,((@=>8;>C=:5;B:46:;;8911.5=:<364CBCEFE8;.*5:?>B?AAB?+,+&&*.,1A=<@<=@@./:<:8;>8CJC3/9:>:B0EAC=<><>98)B@=6;)('''/194>>@(?13.&:0::<;@:685AGDDDA>F895=978>CC@>8:5>;AEBC?;=A?GCAA=GEJ2;==;.'108@HIB884114;679978?:1(-%% +@SRR11410539.967465 967465/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAAAACTACAAACGGAATCGACAGCACCTTGTAACTGGACACATTGAGCCCACAATTTAGATGATGATTCTACTCTGAGTTGTTGCAAAACTGAGAAGTAAGACTACTGATGTGCCGCCCATCTGACATTTAGACTGTACAGTGGCTACTTTGATGCAGGTTTGCCACCAGCACCCAACAATTTAATGTTGAGTTTGAACTCTGTACTATTCTTGAGGTAGAGATAGTCCTGTGAATTCATATGTCTAAACTCTGTGTGAAACTAGTAATCATAAACACCAAGAGTCAGTCTAAAGTAGCGGTTGAGTAAACAAAAGAAGGCCAAAGTAACAAAAATAGCCTAAGAAACAATAAACTAGCATTATACACTGAGTATATTACCAGTTATGAAGAAAATAGGGCAATACTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTATTTAAAAACCTTAGCAATATAACT ++ +)3735466<911('(0../7;:?58>B;>>D@>AFBEE).;;;;806:@A+?;;=@>EB?:/4454:@?AEE@BEDA?>9&(#%),&&3475D489?>@BBDC?==6>@(1>899:HBA96$+5%DCBI?>@''.*'87>>?&&A:;9ECEF:=ABD?CBC67)+21;1&''85=@@:75($+,'$%$((366**00(6654H>>602%$()'$%#**)'%%$*'+/,''*%&*,/+,.01.1-%(+.');5=87.>4@BA@=8;99>C>447=@B:0@@,'&+)'*-,78=::222+-9>B<>>1>DAB>?>A@DE<==5&/-389CD@AB?6.-&%''$'-.0;:6,**2(87>F<@:@>=;97889=<91&%047:&239:D8@?<9B;9<-*67*$&('&%)%)5'0$$%%-16.( +@SRR11410539.1453183 1453183/1 +GTTGTAGCTACGTTCCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGGAATCGACAGCACCTACCTGAAAGTCAACGAGATGAAACATCTGTTGTCGCACTGTACAAGCAAAGCAATATTGTCACTGCTACTGGAATGGTCTGTGTTTAATTTATAGTTGCCAATCCTGTAGCGACTGTATGCAACAAAACCTGGGTCACCTACACGCTGCGAAGCTCCCAATTTGTAATAAGAAAGCGTTCGTGATGTAGCAACGAAAGTGATTTCTTTAGGCAGGTCCTTGATGTCTGGCGTCTAGATGGTGTCCAGCAATACGAAGATGTCCACGAAGGATCACGGCTCCGATTACGAGTTCACTTTCGGCGGTCTGGTCAGAATAGTGCCATGGAATTGGCACGTTGAGAAATGTTAGTTTCTGGATTGAATGACCACATGGAACGCGTACGGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACAGCTCCCATGT ++ +''($$$#$)$36=>%.%+8;DF8<<;A;D<1.(7CA9:'0./=?@C@:2=;=9)((1).63<=;;:8.?+:847211/-&#.99@E9>6@/0;>?C7<=<6<$$-/0?512//.78>93D77;1@A<=E:=CF=??7>-8@DF66==;?E@:LH=:AA<=<;>9;566$%%#+DECGGIB@A3@>:<>99;>J5?EFBB===?>@6D527'1&->>1==5CA;5B;DEB=5000&&%'28<7?<;8-;7313*(=DBDB@>13'%$+566;EBC720)4)7<@GD?779<8>A>AHIE;<;<99..+,$''$'%'%$# +@SRR11410539.1086220 1086220/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACATAGAAGTTACTGGCGATAGTTGTAATAACTATATGCTCACCTATAACAAAGTTGAAAACATGACACCCCGTGACCTTGGTGCTTGTATTGACTGTAGTGCGCGTCATATTAATGCGCAGGTAGCAAAAAGTCACAACATTGCTTTTGATATGGAACGTTAAAGATTTCATGTCATTGTCGAACAACTACGAAAACAAATACGTAGTGCTGCTAAAAAGAATAACTTACCTTTTAAGTTGACATGTGCAACTACTAGACAAGTTGGTAAGTTGTAACAACAAAGATAGCACTTAAGGGTGGTAAAATTGTTAATAATTGGTTGAAGCAGTTAATTAAAAGTTACACTTGTGTTCCTTTTGTTGCTGTATTTTCTATTTAATAACACCTGTTCATGTCATGTCTAAACAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +&))%&%$%*&7D1@8>@CC=;<:4569<90+CEA::*:66=3@<>A@AAB:78;3=<>A<9A4?GC?7+7?4D/44DC?//5?@B9B>?@BH?6669789?B5>9::><:=;5>94EHACEBC<6DHG>CEE:81109>6F=>?IGCFFBDAA:1(&&).,@@>?GLBGFKD>A;7?B6DC6/+15<+6334::>111243=?:CBDGMIDAHDHI2)39<6<''&&29<@3,*1.@D664;;60522,168,'';;8:'2$&&%%/;=B1%??B>::80-AD;5256;GEB>=?@C>A@;E=DC>?=))4*+',533=?@=<2@B57C=9<=@:;<:;1&%:00:BEBGCI@MHAFFCDAC?BF@:;;1256;AHINF34+)(>>=>?;=CCEDDD1,:>6&&67<>C>:EBJG37=@>@ABA8:BCGD7=:13EAEBD=?A>@A<>;EAF<;>>AJC?@<7/:;=@77>766:=8<412&,>=??EB:79668<;=%893/+-%%&2,,3:>=:79;D?DFA88=>>CCCB@ABAC>@@?::<>DA>?=4/--,=1355?;87:;.?+$1&&%):A:B?>==DAB@MG?2B2EDBAB>9@=<239#374=<32(#&&/142+65103;77FC=:F<22CF?C8>9@785*)&&$(/3;;===-7+ACFDFH>BFB77C?;>@>;==<90;<:5-*)*(4((868>;@K6,8'19859((((%&%$$>>@GAA?A>=?C?><;B@@?:>>>;M@258:;EAB=<:+&44;912323..((((:;@?DD>31& +@SRR11410539.299474 299474/1 +TGATGTGCTTCATTCCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTTAGCTTGGTTGTACGCTGCTGTTATAAATGGAGACAGGTGGTTTCTCAATCGATTTACCACAACTCTTAATGACTTTAACCTTGTGAGCTATGAAGTACAATTATGAACCTCCTAACACAAGACCATGTTGACATACTAGGACCTCTTTCTGCTCAAACTGGAATTGCCGTTTAGATATGTGTGCTTCATTAAAAGAATTACTGCAAAATGGTATGAATGGACGTACCATATTGGGTAGTGCTTTATTAGAAGATGAATTTACACCTTTTGATGTTGTTAGACAATGCTCAGGTGTTACTTTCCAAAGTGCAGTGAAAAGAACAATCAAGGGTACACACCACTGGTTGTTACTCACAATTTGACTTCACTTTTAGTTTTTAGTCCAGAGTACTCAATGGTCTTTGTTCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +#&%%$%%9;=7(8:)-2>BD??;B??A//,9:.C5;..'(./68FD>;86@BAB;>>D?@PKF?<6%->?D9A?AFDG?DRRHCC>9=@?,;%845053.)(*;?ABA?.):<=:9>%)??@;E?78@ABA@>?@?:1+666/3>4<<248@AAICC13ACDEE;?DFG=;@9<>==:;11;=@A>%798()*9;?8966%&77:>@=>;?FGCB=73<8:>>ACB>=01&&'(-85;@F?%%&BB:DDADDEB:5$9=HBHBA9:4AG'?DKEII=:9049<3=@C=E;;?;>@A9DC??><85+5?<@HB?=))/;98;=I;1:2:>=;:9''.0%$*022'AFFD@C>?KB=925/))%0+/865>===>$0:GFLDGEE=?=>A;<<@=B>:8:AG?BDECIBCE<1$* +@SRR11410539.1301140 1301140/1 +GTTGTACTTCGTTCAGTTACGTATTGCTGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGCTGGCTTTAGCTTGTGGGTTTACAAACAATTTGATACTTATAACCTCTGGAATAACACAAGACTTGGGTTTAGAAAATGTGGCTTTTAATGGTATAATAGGACACTTTGATGGACAACAGGTGAAGTACCAGTTTCTATCATTAATAACACTGTTTACACAAGTTGATGGTGTTGATGTAGAATTGTTTGAAAATAAAACAACATTACCTGTTAATGTAGCATTTGAGCAGGCTAACAAACATTCGACAGTACAGAGATTGAAAAATACTCAATAATTTGGGTGTGGACATTGCTGCTAATACTGTGATCTGGGACTACAAAGATGCTCCAGCACATATATCTGGTGTTTGTTCTATGACTGACAAGGTGCTGTCGATTCCGTTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +'()%%&(+.23C)-&:9=@C==;;:658$(36>@?2//)(415.55=<21#%%$'*.(/)+-566B760-,*+,-+89<>:=8;AONIBA>@/C@CDFA>>;9,,,=A89-$'+)74;074BI75-&&%4455002+.'$$#$#%&.)&$#%(5:7A=?E?HB0)32<>;4.';'*:;;:9ABJGFFCBC7D).95312299@AAFDD@D47?@E>::/+----/48>E;77A@@AC>?G?HF==ADDJHEGGG=92)'%%$$$)&.(*(1%#%$**+'*/)'%$$'$%'''>@@=?@A7C@A@7;79>157BCC=?=AD@9:/27@B:>/0.)(-27325-?<>@A;A@4+::::;98567&7,..03--,$'#*,./14-,*(%1>?)+-.6;@0-??1)+*3:>:54?@=BADCCD?>C?862$-7:DAEGIFE:;65:87A;C--0E=?A=89>A<87*+94(.&)*+*'#$*0;=>@CB91))/<=2C7EC/(),-1-$%'(+4415=<;98DB?JHE=?73;29:=@5282><@ECF@BB=?:5997'04.3--&'%#$%-611?:385:$:9>EB8898;A>8886139%5603:;>@;<>DD=)*'%&&'.)&%%+/#&*-2;?><<4648@A@@=MJ,,5+*//>)8:8<:;5$#$$$,299;;7/((#%,#"%%&&(*&#&<;@>82%&*%#$%''$'-12768F=?@CC>>>5(+# +@SRR11410539.1842478 1842478/1 +TGATATTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGGAGCTAAGTTGTTTAACAAGCGTGTTTAAAGCTTGTGCATTTTGGTTGACCACATCTTGAAGTTTTCCAAAGTGCACTTGCTGTGGAAGAAAGTGAGTCTTGAATTTTGCCAATAGCACTAATGGGGTGGTTGGCAATCAATTTTGGTTCTCATAGAGAACATTCTGTGTAACTCAAGCCACCGGTAAACCTATAAGCCATTTGCATAGCAAATGGTATTTGCTCAGCACAGCACCTGCACCAAAGGTCCAACCAGAAGTGATTGTACCCGCTAACAGTGCAGAAGTGTATTGAGCAATCATTTCATCTGAGCAAAGGTGGCAAAACAGTAAGGCCGTTAAACTTTTGTGCACAAATGAGGTCTCTAGCAGCAATATCACCAAGGCAAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +&+&'%&*%5560:E:?7=I0F;:ED6A/1074;CE=@CCCDC@5:@B;@@I@@=AA?A@@02&>@?>?@=B8384>?AGG@<3F>EF@FO91---+0594A96:632771=;A8=>?=BFSM>=?<4*%%%%6:%%5$&$$3&-;?<:*-(..<91$*9BG@E@IDEGI@E?3782.&)2><;><;=187:<><($&($%%$(**,:987.%%*>BB)16**;88=5+)++)8<>FKB96?EF??ADD8455,2??>+>?AE?>;;=EB;7>)A?:=>JGCD;>FEEC2BA<<6C00?685>??>$=:C@AC?;???DFBE9@@JCBAA=?:;=?9676/0,,+,+((((99A75))& +@SRR11410539.1669469 1669469/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCATCTTTAAGATGTTGACGTGCCTCTGATAAGACCTCCTCACGGAGTCTCCAAAGCCACGTACGAGCACGTCGCGAACCTGTAAACAGGCAAACTGAGTTGGACGTGTGTTTCTCGTTGAAACCAGGGACAAGGCTCTCCATCTTACCTTTCGGTCACACCCGGACAAAACCTAGATGTGCTGATGATCGGCTGCAACACGGACGAAACCGTAAGCAGCCTGCAGAAGATAGACGAGAGTTACTCGTGTCAACGACAGTAATTAGTTATTAATTATACTGCGTGAGTGCACTAAGCATGCAGCCAGTGACAGCCACACAGATTTTAAAGTTCGTTTAGAGAACAGATCTACAAGAGATCGAAAGTTGGTTGGTGAGTGCTGAGTTCCGTTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +$125?>>?A;AD.4,62-$?@CHGI>>B*+:DDA@AC;89HFCC4B1:90&():*:>.4+59G9;0@=>;)90000@>-C>B=833431@?@E><901,0,*(./1/1/=;03267;;?:+=@D79B>AB@?B<2;@?;7440',&-65/=>>@BC?>C9=85:?;:89?@5>=C>D;>C5HA@ABFCD-.<2D>D?;44<;68;BFH9CD>EBC525,5,%2-(,(,+*$-64;%&99<913@;;:91BBA;9;454897(%78::>>?FIFC.=?II7>?@BHFFB;&,CEB6@0DB=>9GGEDMKN@FJ:>F?<>>D6;EB9:D;+&,))'3)))*'&&(%'&,1<>>6.192*8?77??9;;:;:@=8:ACCE<@:03,* +@SRR11410539.712190 712190/1 +GTTGTACTTCGTTCAGTTACGTATTGCCTGAGTTAAACAGACGACTACAAAACGGAATCGACAGCACCTACTTTTGAAGAAGCTGCGCTGTGCACCTTTGTTAAATAAGAAATGTATCTAAAGTTGCGTAGTGATGTGCTATTACCTCTTACGCAATATAATAGATGCTGGCTCTTTATAATAAGTACAAGTATTTTTAGTGGAGCAATGGATACAACTAGCTACAGAGAAGCTGCTTGTTGTCATCTCGCAAAAGGCTCTCAATGACTTCAGTAACTCAGGTTCTGATGTTCTTTACCAACCACCACAAACCTCTATCACCTCCAGCTGTTTTGCAGAGTGGTTTTAGAAAAATGGCATTCCCATCTGGTAAAGTTGAGGTTGTATGGTACAGCAGTAACTTGTGGTACAACTACACTTAACGGTCTTTGGCTTGATGACGTAGTTTTACTGTCCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATGCAACTT ++ +&-0(,-;>A6=G0+$(.3374::EESEAGJ@E:=FKDA=7=0?/.+-.-8F?JKCD@5--*39<88@?76,<><:LM@B>@>BGFDJ4B?==8382<==A=9B@AFFE?BCD@81()1+1=A:C>95:68;579@@:@A440:@;=<5<@CA;>D=AB9-.::7'-8=<:?AAC;=30?A9B43-&$7@?@ALJD@CDEEHF@@@C=E?99>@100+;CD/AAB>@7/<978>&?C=DHF>?QJA@E=:;B<>DFI>87IJFAFB?DH@@>?B939A=@ABEH/0;3+)(4+2>?A@<=60*'$'3-9::+++))-1,&=57?D94-%%)23A9==>FDG=?))@@A<2177434FAFDCA@=&&@11=7<4>BB@9?;929===?;;=449:7...1-*-$'%%)%.$$**( +@SRR11410539.1602242 1602242/1 +CACGTCACTTCGTTCAGTTACGTATTGCTAGGTCCAAACAGACGACTACAAACGGAATCGACAGCACCTAGCAAAATATTGGACTGGGCTGACCTTACTAAAAGGACCTCATGAATTTTGCTCTCAACATACAATGCTAATTAAACAGGGTGATGATTATGTGTACGCTTCACTTGCTGAATCCATCAAAGGAATCCTAGGGGCCGGCTGTTTTGTAGATGATATCGTAAAAACAGATTAATTTACTTATGATTGAACGGTTCGTGTCTTTAGCTATAGATGCTTACCCACTTACTAAACATCCTAATCAGGAGTATGCTGATGTCTTTTCATTTTAATACTTACAATACATAAGAAAGCTACATGATGAGTTAACAGAGGACACATGTTAGACATGTATTCTGTTAATACACTTACTAATGATAACACTTCAAAGGTATTGGGAACCTGAGTTTTATGAGGCTAAGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +#$$$$+$$)'09?4946C634298:;*(*)(''%%-1*;<;>CEHAF@@GFDD8:B?;E;:A85)*+,BEIG>C@<9?-.30*+.9@<911)''19=A-25C>@C;8476,5.3587)+$%%(.41472&"$%.14457<=FH5>GC==D544<=278<9/1A=AK@>B;1JKH?995+&&01),7224:BE=4522.37:34<@FEC;442=B<<245;5786866227>@:;9:.>2>EDE79@(8;ACK;6:;GGM=D>?8:789%%,46<=:778@9:@?8=EB@14( +@SRR11410539.856880 856880/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAACCTTTCCACATACCGCAGACGGTACAATTTGTTTTAAGTAAAACCCACAGGGTCATTAGCACAAGTTGTAGGTATTTGCATACTTACCTTTTAAGTCACAAAATCCGCTGCAGGATTTGGATGATCTATGTGGCAACGGCAGTACAGACAACACGATGCACCGCAAAGGATTCTTGATCCATATTGGCTTCCGGTGTAACTGTTATTGCCTGACAGTACCAGTGTGTGTACACAACATCTTAACACAATTGTTGATTGGTTGCCCCCACTAGCTAGATAATCTTTGTAAGCTTTGGCAGCATCTACAGCAAAAGCACAGAAAGATAATACAGTTGAATTGGCAGGCACTTCTGTTGCATTACCAAGCTTGTAGACGTACTGTGGCAAGGTGCTGTCGATTCCGTTTGTAGTCTTCTGTTTAACCTTAGCAATACGTAACT ++ +%$%'328<>>9C8+'79<<1(637:310894'>HEIMFC>?A7,,)+(,,2293712=>?A9H6B;?97::@A@DB;?6B:=*2@@:%&%)8+861,03++%%DGIID'7;@@@9;$$&)55::BDB2I.3/4=@9DB>&-*)002>DDAA<>B:DHIFC((-'(*'$%(7%AB=6;CIFA;?=:552*-<22;./.,/33<<=AB:75/977EBC@:;/>>?'.A8DEC?ADA7CD?;26FCEC9>A:61(59--+-&&408B:?<>AAADDC?+&(3:EB.4?@/+/44456/38:;..>5=D>AHGB.0..)$$'+$(<9@=?;B?21/01:;823/58$$:5&0=8+)'&.+046677:>69-%.A@G@ECE@;IH=EAB9)((#$$$$%$(-/A94837E<3144'(1:ABBEB=FCEP8597GEH:762'%#$&%(7;=999<=:189;;CF>;:2.$& +@SRR11410539.1506430 1506430/1 +CTAATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTAGGCTGTTGGTGGGAATGTTTTGTATGCGTCAATATGCTTATTCAGCAAAATGACTTGATCTTTGAAATTTGGATCTTTGATAAATCAATTTGATGGCACCTGTGTGGTCAACCGTTCCAGGTGTGACTTCCATGCCAATGCGCGACATTCGAAGAACGCTGAAGCGCTGGGGGCAAATTGTGCAATTTGCGGCCAATGTTTGTAATCAGTTCCTTGTCTGATTAGTTCCTGGTCCCCAAAATTTCCTTGGGTTTGTTCTGGACCACGTCTGCCGAAAGCTTGTGTTACATTGTATGCTTGGTGGCAGTACGTTTTTGCCAGGCTTCTTAGAAGCACTCAGCAGCGGAAATTTCTTAGTGACAGTTTGGCCTTGTTGTTGTTGGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACATAGCAATACGTAACT ++ +&(&&*1.+))),+8:882649?75=98;7<@241?ACEH;66674%%%/&%/,*1&()77786,/'''%'&'.($$,8AB>=A:;&677868>=68?B?;1.9//-2****,BE;ECA;>?:=994;<84189BB;?=;=*A>9;:563586,,++%(19=:>>F?A>=<=784.))'(1;D34:.5;8.0$&::;55.'(+(*(-/?>?@CD@GBC??C8(::9,'?DFCB94034-69<58EE882-++2589734/4>6:44=633:;=?A4:<@9A;A=7)+*//+:1E7==:=A>5768889;<;HG;>:=@'*''37AMI:722-=@A6>:7?:9>(64/.*1152238BC;:04&',(&&'&&&&&,822,(8774?D?MD?995168++5=6-=*><(5('/.0%,*)+$%'(,896+**04566$%('+.:80-+-732665:84994:;AA>27=<7::@A:714780:&9>5=AA>FEBA4.%( +@SRR11410539.1270606 1270606/1 +GACATGCTTCGTTCAGTTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCAATTTTGTAATGATCATTTTGGGTGTTATTACCACAAAAGCAACAAAGTTAGGATGGAAAGTAGTTCGAGTTTATTCTAGTGCAGAATATTGCACTTTTGAATATGTCTCTCAGCCTTTCTATGGACCTTAGCGAAGGAAAACACAGGGTGTTCAAAATCTTAGGGAATTTATGTTTAAGAATATTGATGGTTATTTTAAAATATATTCCCAACACACGCCTAATAATTTAGTGCGTAGTGATCTCCTCGGTTTTCGGCTTTAGAACCATTGGTAAGGAGTTGCCAATAGGTATTAACATCACTAGGTTTCAAACTTTACTTGCTTTACCAGAAGTTATTTGACTCCTGGTGATTCTTCTTCTCAGGTTGGACAGCTGGTGATGCTGTCGATTCCGTTTGTAATTCGTCTGTTTCTTCCAGCAATACGTAAC ++ +&#%&''/02.:A/($+,-(*0+/:,,++9:GHE<55916/27=8CD98*,295740.*011772@@@AEB?++*+--+%07<=I@379==2,%&)&01)+,-*'$%)*.<<496,$)(()$(*.%*$%&.0+$$)9==8;,;(%9?>,+&,269>6997''&.)78:9A?,%)*+)$&%$%+58<>?6632.17780?>0&&')))$%,-AAC@;/-8+/+*%)**)588@>>>?A=(*&$%%'..5311.&'(-..:48/6-.(*.(*%'79>3:73#'6;<;>?.2'&)59==>/1.%)$$$7=C<>:23(0&/41/1)-56/===?:9=EBA;./):AB@9;>?99>>8,'.+*,--85*-.%$%)&%3/0)*#(($&'2$'(%&%#.)*'.,:53A?:=B889&04::8*.))(/998<99650%&%(,(&)68>?7)+%)& +@SRR11410539.1842263 1842263/1 +TGTTGTACTTCGTTTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACACACTGATTAGGAATTGCTATGTGAGATTAAAGTTAGCACACATCTACTTGCTATGTAGTTACGAGAATTCATTCTGCACAAGTGAATATATATCGTAAACGGAAAAGCGAAAACGTTTATATAGCCCATCTGCCTTGTGTGGTCTGCATGAGTTTAGGCCTGAGTTGAGTCAGCACTGCTCATGGATTGTTGCAATTGTTTGGAGAAATCATCCAAATCTGCAGCAGGAAGAAGAGTCACAGTTTGCTGTTTCTTCTGTCTCTGCGGTAAGGCTTGAGTTTCATCAGCCTTCTTCTTTTGTCCTTTTTAGGCTCTGTTGGTGGGAATGTTTTGTATGCGTCAATATGCTTATTCAGCAAAATGACTTGATCTTTGAAATTTGGATCTTTGTCATCAAGAGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +#$#%&**--.&)(5=82.>:>7>7EC?E8+112;BJFAD76-.1)57=61366024/1&&''/0/.2<8C=>DAG67,/+67='&9568:A9>>ECEF/9/10&'$'&.5;B=96692?C=<389BB@9;9722588@@@?BB<=7800+7**-097;=A;=?@>@,31233-*''$%/>BH@JG>;6,)''#(/3578B@@DD.13,9>3;37=:>A???<=;=<;84/761=;;<=>@9446:5BB=DG2@@@<@629;().(())>BC%%?66612.,2-41/<;?EC:704C9>@85CEAF.,FB@BC=BABC==@DAC78&/7:;<+(((+&9/?5=0.34,44?@:E?;?>FD=55A?CDB4199:5>>?DC=>>B82<49BCAD;:B9:8><8:JH?;97>?CH45/(''?G@>A<6A*+9+9=56628=@=KA<>6BAH=;C?<>;:<335:=:95320.+:BC>>D?>--* +@SRR11410539.2039774 2039774/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAAAACGGAATCGACAGCACCTGGCACATGGCTTTGAGGTTGACATCTATGAAGTATTTTGTGAAAATAGGACCTGAGCGCACCTGTTGTCTATGTGATAGACGTGCCACATGCTTTTCCACTGCTTCAGACACTTATGCCTGTTGGCATCATTCTATTATCCGTTTATGATTGATGTTCAACAATGGGGTTTGAGTAACCTACAAAGCAACCATGATCTGTCAAGTCCTTAGTATGCACATGTAGCTAGTTGTGATGCAATCATGACTAGGTGTCTAGCTATTTGAAGTGCTGTTAAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTGTAGAAGGTTCAACAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +'+-231:>8;=HF0,<22.?>DA=DAC?9=/25379F==5777:2$A-2A<8555//-)'%%3645GG@9=>BE?8:9?:12'&&*/,0177C:CE879>>:A=;<444450@;@=;;5&&##"$+/:@A70?@AOFB>EAFEE67BEHF=>@B?9,)%%+7;CAAC=DDC<9%&@@?>:5.3.%6?*+-..3++'+*5<=CC@FBD@>@C9;??B@>@AHD>>A@B?@??:7;2.>72:12--+&+,-65-7@'&FELH>>65/D9CC=<8;790,,*)-4/<='./657:?CBB:<;:;;4257955*(::<;>;>879-6'0+9;731'*%254;<<29?B@?;<9==;7-=>@?9:89CBC;;;A?<687:7**.&&../0$)$%$(;970<;9:BGBC87'$3*86::=:9:255>;@;1113=803=>=<:9;&'+'%9EB?@=43,-,,047::5542,),.:=?039=;;;5.&'%(-,-00/38?7:;><6/2,,+*%#$$(2::9999;050:;@:<@>ED;2<:;E0>6A@B7:IDBBB:479++27=>29==,(+:6;0.)/2552/+,16:<>AF=@49+%0012<6:1:7,=C?>2$,+9'@<=58967:>AB@;=44,739=A@FB0<,832301:;6:0?BB>==<@EFNA>?;ABG:9C>?ADD:98FSIFG-.)/);?@@8/'601/765492*8:;*4EEA7D9:C;>*9ECMLBE<>()'()()4.;,9:<14?>?7DBA65'*&*(:>@5;AH4+9$./?>??C>A42:A@A:@9D@7A:>DAFED?A&:23.4/226?:>4/@EEMC;;A67CLFLJC=?=,))*>>BGB>=A>=?C@?::;=AC<:6***%&'.*+-1;@A79&'&)+.=><.&&*/BDHC;<$&%&-6-0$(559>@?C62GJD=<%/DC:#%#$$'%%$)/*,.8/.4/483&(%%&/#$$$&9;AFD=>2556CB@A?90<'::;9-%&7511)*(=*;ACCA4@8<:<45020&8;64,%&'))2)1%%%%(1.%&915<9<>;:.,&('%(#%$%&())(,(/0-)$2240.-3,%&$00,>@CB@==>AC40;360:<510++573900-$13/*&')/'))*()*)+,'*+.,(&&0)/25///6>B?=?,=91/.2.-$)$&#'+-32,.$/22:773)1**39DB=8063/9=@@C66:;;.)19=@=3(*-)+/00.)+4610.4)55;>?>9@>@???D70<)*+%$,&*,*36<=:0'+54407331-116&--*'(-/36*+433++&+1'+,+*%$$%)((/''6AA91>66541==532*//')'(000688<55--.$%%*,-587=AAD;=F>7&4*(#'''),(+-,./-*((-5)*A<.6,++(/(,,4,9?@;:>443.67:872356456597'$$#%$$%$%%,'$'&# +@SRR11410539.848688 848688/1 +GTTGTACTTCGTTCCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGGAATCGACAGCACCTGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCTTGGTACACGGAACGTTCTGAAAAGAGCTATGAATTGCAGACACCTTTTGAAATTAAATTGGCAAAGAAATTTGACACCTTCAATGGGGAATGTCCAAATTTTGTATTTCCCTTAAATTCCATAATCAAGACTATTTAACCAAGGGTTGAAAGAAAAGCTTGATGGCTTTATGGGTAGAATTCGATCTGTCTATCCAGTTGCGTCACCAAATGAATGCAACCAAATGTGCCTTTCAACTCTCATGAAGTGTGATCATTGTGGTGAAACTTCATGGCAGACGGCGATTTTGTTAAAGCCACTTGCGAATTTTGTGGCACTGAGAATTTGACTAAAGAAGGTGCCACCTACTTGTGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACAACTACGTAACA ++ +$02*,(;<==C=:;;89@AB447DHEHL?798?476669:78-/(*))99@DD?B@B:D>>/3CDCB?>?C>=HA685;DDFC@BCCDHE?B=?CGL@9?7>=;851.1339?CCD?B?96GA/1;@DLJHE@=H:=:9;GGCC@<@@=A?7D@BD?:5-2)%')()())>>C80/1&(+,,)#%((:9A771255@=<<>EH?49><<<;<===<;D;06(+.2>@I22@<:;8<9=<>@B9+:=BE4:?A>DEF>@?KK=B@E@@:69-,0032)6=B@ASOMF.B8./.'6629FF@@<:D448624C=A>IHKHECC;?A=>?D@?<;;4325'&($%#'&'%,.1/( +@SRR11410539.715925 715925/1 +CGGTAATACTTCGTTCAAGTTACGTATTACTGGGTTAAACGAACTGACTACAAGCAGAATCGACAGCACCTCAGCCCTATTAAACAGCCTGCGTGTTTGAAAAACATTAGAACCTGTAGAATAAACACGCCAAGTAGGAGTAAGTTGATCTGCATGAATAGCAACAGGGACTTCTGTGCAGTTAACACCCTGATAAAGAACAGCAACCTGGTTAGTATTTGTTCCTGGTGTTATAACACTGACACCACCAAAAGAACTTGGTGTAATGTCAAAATCTCAAGTGTCTGTGGATCACGGACAGCATCCAGTAGTGTCAGCAATGTCTCTGCCAAATTGTTGGAAAGGCAGAAACTTTTGTTAGACTCAGTAGAAACACCTGTGCTATTAAACCATTAAAGTTGAAATTGACATTTGTTTTTAACCAAATTGAAAGTATTAGACTTTTTAAGGTCCACAAACAGTTGCTTCGGAGAATTGCTGTCGATTCCGTTAAGTCGTCTGTTTAACCTTAACCCAATCATCTTTTTA ++ +3&('$%&'*+1,=>,4#%(#$+/)+$%%112*+<;==>01%%&$$*)**((56&,-&&&59>D>;ABD998)&&5%%:<47CE??<>D>+.8?IBBBG@@LKI>?5600.25:5//'<;OJFEDG<95@@=887@FF7;?AFIO@.HKEJ?ADEAAJCFD02$--;>C@@=&)5,,;7DC;>33;3(-'<..'136-6/14@>>@;<>CD71?B@AFA87;A:''8/74/09;907):9;:<<=A@:821/1/.66BBAEEKA&4:99B<6*,$(%$'*(//,,)%)$&&$&&589=;/02(,*(-/+*2446>>(AEGB-??F<;444B02559'''&$$(&)%%),//10.$$/+*,/'(15-849:2($$%&&(($(&&0,3>>;9;11+)'0*436511?7=CG78;A>CDDD>A;5+-)&'%'%%).)$#%'-58DG.*=<23A>51../;=BD55C6+;))+0189ACAC@EDDIIKOH?9B?/039911-<;:70/$+$-3+)'*3=>DA8=IF=;G:97;@<99;;=?<4*))*:>A;=:;615@B<==CD@=A=?BG?B;=<1889;;8F><45>4312,*><467988/)),0645.'%++%,)%$%$)+022;49@:6>=@B1A;;9:33/%&12272)6//;<>A>B?@95CD>B68897BBB?@@B@53, +@SRR11410539.1031143 1031143/1 +CAGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCACAACTTGCGTGTGGAGGTTAATGTTGTCTACTGTTGTAAACACCTTAATAGTCCTCACTTCTCTCAAAGAAAAGAAGTGTGTGTCTTAAGATTGTCAAGGTGACTAACTTCACCATCTAGGTGGAATATTGGTAGGATTACTAGTGTATATACACTTTTATCCTCTCTTAAGAAATTCTATACCTAGTTATTGTAGATTGTCCAGAATAGGACCAATCTTTATAGGAACCAGCAAGTGAGATGGTTTCAATAAAATGTTCTTCAGGTGTTTAGAAGAAGAAGTAAGATAACCATTATACGCTGTAACAGCATCAGGTGAAGAAACAGAAACTGTAGCTGGCACTTTTGAGAGATCTCATATACCGAGCAGCTTCTTCCAAATTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACAACTC ++ +/()*...;;=>CD8>8>?=<63GCEF::A//AGHEHL<@>>E>=89966880./2687.>F9G5A@=-,)0?BF@+1:7I9:DFGDECDC=CCB@@>ACGD9:;>9=67:EG=;?FF/-:93+'=8@C='D&F@DB<()4$$,.(.77&)9--&266028('''(66<7?9;),44---18;BB<<6CC:<8>6A5(01+(4<==BEG@:%%(89C<=8'(**+226>8>9=928123/$$(:;:;64;@--=66.:<>=D<>==>89DE@A74>7?:8@9@9<@AEBA=,7-)&('-489)BD=?43CEG>@A@HLFA<@B>>BEE><9(--+67784=/**@@>/GDHE;;DAQE0=F>::94:<:=>A?9?@@K@AB9D@A4235.:79989./*$%$)$%((0)'$+& +@SRR11410539.1943800 1943800/1 +CATTATTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACGAGACGACTAAACGGAATCGACAGCACCTAATACAAGCACCAAGGTCACGGGGTGTCATGTTTTCAACTTTGTTATAGGTGAGCATATGGATTATTACAACTATCGCCAGTAGCTTCTATGTCAGATTTGATGTAGCTGACAATTTAAGACATTCAACAACATCTTTAGTTTCTACATCTGAATCAACAAACCCTTGCCGAGCTGCTGAAATAAAAGTAGATAAGACATTGTCTAAGGACACATTCTTTGCAAGTTCAGCTTCTGCAGTTGCAACTAGTGTTTTGAGTTTTTCCATTGGTACGTTAAAAGTTGATGAAAACGTATTAGCGTAAAGCATCAAACATTTTAACTGCAACTTCCGCGCACTATCACCAACATCAGACACTAATGCCTGATCTAGTAACAGTATAGGTTGACACATAAGCTGACTGTAGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACATAGCAATACGTAACT ++ +&$'(%%.)56:;CB5B?HH@HDBEAA7B@=//.)#*&7*;'1(69?:*%:?CF7G?ACGFBC@CFB?E@9K@EBB9=D9DF;>BAEDAH5733))@C=98898?;;553:?E>;)/(:8.'04737$9?;=;:4,;1G%%%(AAE<.%715/())262.(''&19868;98445;1::<=>=80:;GGCDCA3,8,-=;39>3=B=A:75@11?BEED>>>A>A><:78E:;@A>DF?CD6.3;A5E@?A9@@8F;7':=7788<92@9:=A;I@BDB?A952)>),(3005377>??:<;;9DIERKH;>55957BC6>CB66'()C>@A9115GC46A>?24&,)**+)37934-09CBEFQEA;5JIB92,?@>A7%)*>?3:ADBF@CBH2@A11D<775??B@C:034AAJJBAHBBA468?AE;4147=>?@?B@@D<0=%?B:>CDAEB;9&&#% +@SRR11410539.2287969 2287969/1 +CAGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACGAACTGACTACAAACGGAATCGACAGCGCTGGTGTCTGCAATTCATAGCTCTTTTCAGAACGTTCCGTATTGCCAAGCAATTTCATGCTCATGTTCGGCAACGGTAACACACCCTCTTGTAGTGTCAATAAAGTCCAGTTGTTCGGACAAAGTGCATGAAGCTTTACCAGCACGTGCTAGAAGGTCTTTAATGCACTCAAGAGGGTAGCCATCGAGGCCACAGAAGTTGTTATCGACATAGCGAGTGTATGCCCCTCCGTTAAGCTCACGCATGAGTTCACGGGTAACACCACTGCTATGTTTAGTGTTCCAGTTTTTCTTGAAAATCACTTCATAAGGATCAGTGCCAAGCTCGTCCTTTAAGTCAAATGACTTTAGATCGGCGCCGTAACTATGGCCACCAGCTCCTTTATTACCGAGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +)$&$)/-9@A?>I54/0=@><:B==A===**68>A<@=;**2((@<<9+412-314-79;@<,-+($)/%)19@C@EECE@DEB=;CEC?<:>53753+)%.,('&*%++-,0466ADEFK?B:BDBDEFAD@@+23@&'6'-2#$$%(68902>:8))48D:4CEFB<<>==@LIECHB@BA?FI@B@HG8=()68I34442::.)6$')?@>D<9533B9;?9:E;@CHE=>?;;:/AB?88,,97@@@=C4HE@AGADC5//BDAD>C=2.*&+22289CCC@>;?00@A@ADE=8:@B@:.54>45;77(**22=82'%#&47A<=BG6F5+>49IAGEBB:B@@<&&.&((121)?77&6?A>?B=A=A?5ACDIC?ADFGDBF@JF=/6>A>@@=AF?>@G>?;:9:HBEFIDA8:8$&& +@SRR11410539.716146 716146/1 +CATTTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGTTGAGAGCAAAATTCATGAGGTCCTTTAGTAAGGTCAGTCTCAGTCCAACATTTTGCTTCGAGGTGCTAAAAACATTGTTTTGATAATAAAGAACTGACTTAAAGTTCTTTATGCTGTAGCCACTAGACGAGAATGCATAAGTGCTATTGAAACACACAACAGCATCGTCGAAGTATCATCATTGAGAAATGTTTACGCAAATATGCGTAAAACTCATTCACAAAGTCTGTGTCAACATCTCTATTTCTATAGAGACACTCATAAAGTCTGTGTTGTAAATTGCGGACATACTTATCGGCAATTTTGTTACCATCAGTAGATAAAGGTGCATTAACATTGGCCGTGACGAAGCGACCGATGTTAAAAACACTATTAGCATAAGCAGTTGTGGCATCTCCTGATGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +$#%%#(/=D7-&866@B=BGEG;;?--/<:996*+*//34476>@;6:;ADAKEGCFE=98:AA=-8;>:993*579=ENGCAB'(73-=580626/000E==D>?FRK4=F/+($,,+$#*6:;4,?GLK?DEPGDGFFLCIQO,FJ@DICAGCJK68DEBOKB<##'2&&6778@=@>;,&'$$$)$(,42;=8:;DCA;GH:<@@BHA>FBC=?F=?=77B@;BDIHD=;=>=-B>A44AE?HEHGH@@B69.;0A<=B@:,,>B31<@84>6EHA=@<@FMC@CDDE==>>DHEBB66:4736CH9JIC=?62B9;@F=?<@B*(#7./6?B@@IBFG?;??=ED>((%%%%/+)*%(-8@D77,:<=:;<;=<599<7+,*1-378+7>BDD?CF$'GD90>+2=>@?C?:33,-1#%##'A&266<2:4@6:BBCBBCBIFI<>BCA@EG@-1& +@SRR11410539.1105915 1105915/1 +CGACGTACTTCGTTCAGTTACGTATTGCTAAAGGTTAACGAACGACTACAAGCAGGTGACAGCACCTGAAGAGTGGGCCTCATAGCACATTGGTAAACACCAGATGGTGAACCATTGTAACAAGCTAACACTGAAAAAGTCTGTCCTGGTTGGTCACGAACAAACTTGTACATAGGTGTCTTAGGATTGGCTGTATCAACCTTAAGCTTAAGATACAATTTTGCATAGAATGTCCAATAACCCTGAGTTGAACATTACAGCCTGTACCAAGAAATTATGATTAGACTTACGAATGAGTAAATCTTCATAATTAGGGTTAAGCACATATCTGAGAGGTGCAGATCACATGTCTTGGACAGTAAACTACGTGTAAACCAAAGACCGTTAAGTGTAGTTGTACCACAAGTTACTTGTACCATACAACCCTCAACTTTACCAGATGGGAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACAATACGCTCA ++ +.%%$$&&5553;A/+&0/8CB?FDGG=B5@A(,7++79:&&.9CDBA<;??-.0)%&..)'682;>0''&(%$859<<;>3124240@>CF?A@@B3<**4=5GE5:B<>>BA0BDFC>??=;669@99:8?4448;;8200745:97&&%%&))%%)248223*%$1,735:>>99-2/191GA05=?AA6/@677?::'')(((()&'%'5@A@FOI/;9<=?<;;834>?>7-0;=))(091522,,%*+(,+*+-+*+02444/;;98;3.(%47**;233@=@>>?=>GAAE<>@MBG@?9@H@::'%%&$%&&&&&%%+%-3-444=6>8;>>D<=DC=@C4-0:45$$+%2+(&*+-)$$57*-?;35;75=A;AEFA98;;/1<@>?=@;;B89AFF4)??9:C>9>B<879976BA:>::JF>A>IF@+*&)9945=?=?>7('++*'&'%#&$$ +@SRR11410539.374465 374465/1 +GTTGTACTTCGTTCAGTTACGTACTTTAAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGTTTCCACACAGACAGGCATTAATTTGCGTGTTTCTTCTGTGTGCAAGCATTTCTGCAAAATTCCAAAGTAGTTCAAGAATTTCTTGCTTCTCATTAGAGATAATAGATGTGGTAGAATGTAAAGGCACTTTTACACTTTTTAACACTGTCTTTGCCTCCTCTACAGTGTAACCATTTAAACCCTGACCCGGGTAAGTGGTTATATAATTGTCTGTTGGCACTTTCTCAAAGCTTTCGCTAGCATTTCCGTAGTGCCACCAACCTTTTTAGTAGGTATAACCACAGCAGTTAAAACACCCTCTTGAACAACATCACCCACTATATATGGAGCATCTTTCTTTAAGAAAGTGATGTCAATGTCACTAACAAGTGGCAGAATCTGGATGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACACAACT ++ +'462:7=@C?:KA6)*A@@883/++-7:;*&3ABEF:6;;<=A@B@>32301:===76<;1.;=AB@9486;A?CBBIGHDJ<8=GD?@@GHDGM<6=A@:9G=?;7(&%&?:;;:0+==?.:7-7120)*,&'$&'$$+(;(A&&/47==/6.0,*.5(9<<=5A-9:;>8;:97<5,)23@B;<='&1:=>CDJC@@,+EDC;6(&1>@C<8<85/$%%,7:9<',)/&4+.6998434:<=8BC@B@E53@7?>=8;>@9>GEA&*'+08BADA9@>%%9<>=HG?68>A=<43<79<>C;@:7378?B;8@GG;22)4/*,D99B=;=1268:BFF;;<@((*D::3;2429CBH62=<6<7=>66::D@ACAEC;E@AA@:8/0''#% +@SRR11410539.2478545 2478545/1 +TGTTGTACTTCGTTCCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACGGCACCTAGAGTCAACCAACAGAATCTATTGTTAGATTTCCTAATATTACAAACTTGTGCCCTTTTGGTGAAGTTTTTAACGCCGCAGATTTGCATCTGTTTATGCTTGGAACAGGAAGAGAATCAGCAACTGTGTTGCTGATTATTCTGTCTATATAATTCGCATCATTTTCCACTTTTAGAATTCTGATGTCCTCCTACTAAATTAAATGATCTCTGCTTTACTAATGTCTATGCAGATTCATTTGTAATTAGAGAGAGTGATGAAGTCAGACAAATCGCTCAGGGCAAACTGGAAAGATTGCTGATTATAATTATAAATTACCAGATGATTTTACAGGCTGCGTTATAGCTTGGAATTCTAACAATCTTGATTCTAAGGTTGGTGGTAGGAAGTGCTGTCGGTCCATTTATAATCGTCTGTTTAACCTTAACTTAATACGTA ++ +%'./8:7881;=C@','.5:7E?EEMK@?E>>-EGFEJ?<;;@<:17705,.-*%(1796:8>%/@6DA8>4/,%<,-AA66>H:E9/=7GIF8@55-'46>),=@A?@9?EEDF@BDD+@?AA>@HE@68?99;CDEVMFEJID?6$+**3//,(,0:?AABC@C?B=JHFJ<893<6.11>=7@4898:669BBGB=<=;/=?=8;(&?)<+-3=?B3:09<;<8@@OF;>>?DDF/7&&$$'$%'','&&-5/56>??56:49;EFD=><78??:><;65594:;*4;>BKFA;;:<:6,&%$*3159979<30500>355?;>=9*>>=?EIHNF?C@C6?5/3/866=<<>=?+%%8@:7.6/00(&)0%&*=1.4=75$%('+%(''$$&'+*$565368622''&'$%##$1320/%%+ +@SRR11410539.569689 569689/1 +TGTTATTGCTTCGGTTCGGTTACGTATTGCTAAGGATTAGCAGACGACTACGACGGAATCGACAGCACCTCAACTTACTCCCTGCTGGCGATGTTTGACTAAGGTTCCTAATGTTTTCAAACACGTGCAGGCTGTTTAATAGGGGCTAATTTATGTAACAACTCTCTTAGGTGTGACGCCCCCATTGGTGCAGGTATATGCGCTAGTTATCAGACTCAGACTAGTTTCTCCTCTAAAGCAGGCACGTATTGTAGCTAGTCAATCCATCATTGCCTACACTATGTCACTTGGTGCAAATTCAGTTGCTTACTCTAATAACTCTATTGCCATACCCACAAATTTTATAATAGTGTTACCACAGAAATTCTACCAGTGTCTATGACCAAGACATCAATGGGTGTACAATGTACATTTGTGGTGATTCAGCTGAATGCAGCAATCTTTTGTTGCAATATGGCAGTTTTTGTACACAGTTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACAATACGTAAC ++ +#%)($$%$,,,*$&:/<%+BA?B>B>?C76:--/7$5&)$'))*).-.'('+,,&+(-6=6''%*#&3>>=7=:AFH<899673;3;<555?.>*76:8DF832DD?6>58&'-/)%&$%%%+=:=C=BBE7F631@DBBAGDD:;FB>@GEFEFHD??D>BA;D99:5711..8>CG?@?:A@CBA1=9<<54;,25+%%,,./0314=@C<=LHGF<:<:9./5721.+$+-6<<9:<:??D==2724##-2245000.-& +@SRR11410539.478559 478559/1 +TGTTGTACTTCGTTGATTACGTATTATAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTAGGAATTACTTGTGTATGCTGCTGACCCTGCTATGCACGCTGCTTCTGGTAATCTATTACTAGATAAACGCACTACGTGCTTTTCAGTAGCTGCACTTACTAACACCAATGTTGCTTTTCAAACTGTCAAACCCATTCTTTAACAAAGACTTCTATGACTTTGCTGTGTCTAAGGGTTTCTTTAAGGAAGGAAGTTCTGTTGAATTAAAACACTTCTTCTTTGCTCCAGGATGGTAATGCTGCTATCACGATTATGACTACTATCGTTATAATCCTACCAACAATGTGTGATATCAGACAACTACTATTTGTAGTTGAAGTTGTTGATAAGTACTTTGATTGTTACGATGGTGGCTGTATTAATGCTAACCAAGTCATCGTCAAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACTTCTTTTTGCTCAT ++ +#&-..3,22'.*1'%#'.5B<=;9-%-''2<9:=>14..5=@FABE?LNHDAC;B@ACF>8FCGHFB>=CDJBFB>BB=*,;C>@@OFEJNHIHGICB=**-:9:./=67@@CADCCB;30,/>CA@F@=AAGC3-36D>>=-?7>DC@<900+'%/--009<88:;C?HHK@@>/%:895-2*(%&%%(-./9<<*+8AEHA?='.13,;8><./94A=EDCDCC''*88;<7799:1118=B?F61:74=;642>=A?8MKOBCEB%=D;>=>AFBB?;==CC>C@>;23&.001592=?BFHF=@>JHJCGD@>B==BEF>?:%%"%)$$$%).###%&' +@SRR11410539.925075 925075/1 +GGTATGCCCCTACGTTCAGTTACGTATTGCTAAGGTTAAACAGACTTTGACTACAAACGGAATCGACAACACCTTAAGGATCAGTGCCAAGCTCGTCGCCTAAGTCAAATGACTTTAGATCAGCGCCGTAACTTCTGGCCACCAGCTCCTTTATTACCGTTCTTACGAAGAACCTTGCGGTAAACCACTGGTATTTCGCCCACATGAGGACAAGGACACCAGAGGTGTCTCACCACTACGACCGTACTGAATGCCTTCGAGTTCTGCTACCAGCTCAACCATAACATGACCATGAGGGTGCAGTTCGAGCATCCGAACGTTTGATGAACACATAGGGCTGTTCAAGTTGAGGCAAAACGCCTTTTTCAACTTCTACTAAGCCACAAGTGCCATCTTTAAGATGTTGACGTGCCTCTGATAAGACCTCCTCCACGGAGTCTCCAAAGCCACGTACGAGCACGTCGCGAACCTGTAAAACAGAGGTGCTACATCGATTCCGTTTGTAGTCAATCTGTTTAACCTTAGCAATACGTAAC ++ +$'('+('('%&$)(:)80A<=B@AFIIJ>@ACD0>B?9:2.*+-&%&%;988298;:6$)#-<=@?;$%-*--,2::>A;3923D:;?56/<+@@<5@>=8343>D@BEBBAFKL>A<816.@?<<9GEEA3383185541<@FACA,5*,-414&*,7??>FC;9;7*1;F;;6:=@69721%$&)+)))4157-6,..../)))(8:;7787>=>11-<$-$6?C=@36;AA2A9;?=C<=:?>9777;87ABF?<97CB;EDEELIKHNLEAC66FE=F<>@5;A<8;?379-//:;467IFAB=;=@ECGJD>8;GFIGC?IG5:5D7<8=>@B<<9=6:5+5'*()+*68=);79/.@>;2-..;::CFF=BCK?<>?>:>G<)7))75..-/$$$5>??D748:GIM:<:/'+&&+598:;:;4.-,/434==8>2//(,' +@SRR11410539.1640915 1640915/1 +CATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGAAACGGAATCGACAGCACCTACAGAATAAACACCAGGTAAGAATGAGTAAACTGGTGTTAAACGAAGTACAGTGAATGACATAAGGAATAGTAAAGTATTAAAGGCAACTACATGACTGTATTCACCAAAAGCTCTTCTAAACCTCATAAAATAGTAGGCAAGGCATGTTACTACGATAGCTACAATACCACCAGCTACTATAGATGCTGATATGTCCAAAGCACCAATAGGTTGAATTAGTGGTGTAAACATATTAGTAAGTAAATTTACAGCATCTACACCACAGAAAACTCCTGGTAAAGATCTGTAATAATCATTGTTAAGTACCCATCTACCACTAGTAGATACACAAACACCAGCTTCTGATCTTTCACAAGTGCCGTGCCTACAGTATGAAGGGTGCTGTCGATTCCGTTTATGTCGTCTGTTTAACCCCAGCAGCCGTAAC ++ +(#'279;>?A?QA=75JIE72;65:726)*3CNIHJ><))2)2/2,3/*+$)65<=?'28>>>I?B=><9331%359:9FLGJAA>99933,=FJFFFDIM>;FBA>HO0/EC?@DIGFCGED>?9=@@;7434,?C8>?823+#158=9:A:6;7;>I@>=@7:>:>@@;=B=?FE@>=7114663EBBBC@>A?0/@@A<8<:**@HKG>BC@@ICC@EFGCA<4C780?89:9;FHC?BBC?;823134959<=@<56=73B=D<=98>4<53381?==A7:G,28&&&*37>9@A@A;%&'1)EEIDBE>BCBF7D=A@80.+-600&'(%)%(%$379=33FA068<:-'''488;==?=<8/0,---*&%+$%(--&&' +@SRR11410539.2211922 2211922/1 +CAGTATGCTTCGTTCAGTTACGTATTGCTAGTTAAACAGACGACTACAAGCAGAATCGACAGCACCTTGTTTATCACCCGCGAAAAGCTATAAGACATGTACGTGCATGGATTGGCTTCGATGTCGAGTGTCATGCTACTAGAGAAGCTGGTACCAATTTACAGCTAGGTTTTCTACAGGTGTTAACCTGGTTGCTGTACCTACAGGTTATGTTGATACACCTAATAATACAGATTTTTCCAGAGTTAGTGCTAAACCACCGCCTGGAGATCAATTTAAACACCTCATACCACTTATGTACAAAGGACTTCCCTTGGAATGTAGTGCGTATAAAGATTGTACAAATGTTAAGTGACACACTTAAAAATCTCTCCTGACAGAGTCGTATTTGTCTTATGGGCACATGGCTTTTGAGTTGACATCTATGAAGTATTTTGTGAAAATAGGACCTGAGCGCACCTGTTGTCATGTGATGATTGCTGTCGATTCCGTTTTGTGATCGTCTGTTTAACCTTGCAATACGTAACTT ++ ++'%*'&&3360=R;4/8>>)B?FCCE87..()/+-1.(-)-;:97?;<;$+$(.:;?>?95FDC@A?>;@9DE?=A:662-..2?BAA9;=>?>>CB@4>JHD@<9;)?A>B=?I<>8A5-73+14&$%,039?><49+2%1637138:>>8:839<.5'7=:<9&36IGD?BCADABK>=,-988&),7;<=9@:BAF@=AAGA>:>ADBA?877AD@B;.?GHJAD@B717.<.2.0E@A8;9<:===>8:JC=<>:;=FHJ5;:=C=D$'<>82;-0=78;CBBALF=@JGDDFHIEGDGHDHADB>6A/?-2A?<@>DDB@666A?FCLBFF.&(/34975'%$#&8=@9;=:;CD04525B8&/''/4(809@=<%&:>AD==<,,$$& +@SRR11410539.1153096 1153096/1 +GTTGTACTTCGTTCAGTTACGTATTGCTGGAGTTAAACAGACTACAAACCGGAATCGACGGCACCTCGGCTACACAATGGCAGCTGCGTGTTTGAAAACATTAGAACCTGTAGAATAAACACGCCAGAAGTAGGAAGTAAGTTCAGTCTGCATGAATAGCAACAGGGACTTCTGTTGCTGATTAACACCTGATAAAACAACAGCCTGGATAAGTGTTGTTCCTGGTGTTATAACACTGACACCACCAAAAGAACAGCATGGTGTAATGTCAAAGAATCTCAAGTGTCTGTGGATCTGGACGACATCAGTAGTGTCAGCAATGTCTCTGCCAAATTATTGGAAAGGCAGAAACTTTTGTTAGACTCAGTAAGAACACCTATGCCTGTTTAAACCATTGAAGTTGAAATTGACACATTTGTTTTAACCAAATTAGTAGAACTTTTGAGGTCCCCAAACAGTTGCTGGAGGTGCTGTCGGTCAGTTTGTAGTCTCT ++ +$$&34244,*(8+-(48:43/+)./'&)%(#9=:67*.')/&0)*0/&$047::61&(:%*8869/5$%$$$,%%--1&&)&$')+86BA@A*+$$$#1---132+9<857>7>J@AB=7C=??35*+*7/.*.%$).().'(***77;51'044:AH90:;?;>@66?LQ;%,=4).&(+.'(0-,...(/7==)%&18=/@78<>3/3'%+-/+&&#(,$$$$.)((-/301=7/'&*5@B=B;@=CBEF89%56();CHJKPJ@DBCDDC@<97884/&*)/+;9G@>AA,*88:G:DFBDND?@EF<4::<58?D:A>DDC?GFG@BFA@;=;C7GBBD8A8878:(--($'$*.0168<=FCA?HH@CDCAD?DBBBHHDIB=JKS?>:1;@E?E>FFA833?=@FHIJ:D?GA<>F;5.;,?@H>?F@BCBABBEHID=?=;>44=C21%%?=I>9D:99>DAFB<'-&,08=<7.,#&$(%++8??AD;@CCDF??99:7+1>>651-,$$%%)$&&&--9;;<<==5589?;57B:9856*?II<5;=0<=<=7=CFFF@?CHHMGBB:KGHIFBF;A@>@HGHGEBB<=;8>0<@?CJG@=/3( +@SRR11410539.1712816 1712816/1 +CATTGTACTTCGTTCAGTTGCGTATTGCTAAGGTTAAACAGGCTGACTACTAAACAGAATCGACAGCACCTACAGGTTCATCTAAGTGTGTGTGTTCTGTTATTGATTTGTGCCGACGTTTTGTTGAAATAATAAAATCCCAAGATTTATCTGTAGTTTCTAAGGTTGTCAAAGTGACTATTGACTATACAGAAATTTCATTTATGCTTTGGTGTAAAGATGGCCATGTAGAAACATTTTACCCAAAATTACCCAATCCTAGTCAAGCGTGGCAACCAGATTGTTGCTAATGCCTAATCTTTACAAAATGCAAAGAATGCTATTAGAAAATTGACCTTCAAAATTATGGTGATAGTGCAGCATTACCTAAAGGCATAATGATGAATGTCATAAAATATACTCAACTGTGTCAATATTTAGAAACACATTAACATTAGCTGTACCCTATAATATATCAGAGAGTTATACATTTGTGCTGGTTCTGATGATAAAGGAGAGTGCTGTCGATTCCATTTGTAGTCGTCTCTGTTTAACCTTAGCAATAGT ++ +$#$%%$%0148;B-2,86;%.),,694@=--;A@<46--%($'.;56:6))@A=)6&'(58>=-)8<>CBC4,12=ME;51;3;?>H@<:=>A>56=<=72**3A@DA6&%'((&##%/6<9/%<@>@65$%#0047337612<;5@B7GDE93>?@@0('(<;:<611673286:;B:=ABA>;=67:E>><>?685+BC:<=7@:;3:2--.6;BBJ.$$:9<=;;43-%.&')#%*73,(97:7349'+*)*,-)1$$+4;=53.%22/10-9<88EA8;:@?<=-,==>D:?DD@?.3<9/4<>??>@A>39.;=7<9A9,>?477-7=<=2,62?@H?B<<%%=@7A8/2EHJIKGIGG;<5/((&&(().-<:A??BCBA>6+718>;2/5(.,+=@<9:?B:::9949<<8A=9<34'+5643874(7:88;110-1(-2+1-/::9CE=88+-*)212,8;=41:>=/<8948;1CJ871118BBE<>B<*G*DIE=;64B@>--/&%'+8//.0--46>)*')9;=D>>F?@>GAA.5E:>22368A=>=@GAAH?=9;<@B716;<@DDAFD@9<3/26:>8+,'-)2:::7<,,1=:79?<>:@=?>GD;?622.0-+26FF?67,,78;BABEDCDED::<<@?//:86;?>:5510%*3*.9=B>C?8:ADGE@4A>A@ECDE?EF?DBDMF9-(8,CFBEA+%BBE@3A:;9>E35CK6;:,,)$'#&,0:8,;9;:71/9>AB?>LHGBA=:=2/.11A/>2;35EDHE@@EBG@>I==E@@A851176=;8()'%+4:;41:?AH>@A9B>;C=@9>A8AE@BB@B09--9976B24GF::7.6BE7/99?.20036:?97748.=9=@DB:9BCCCB?D4B?AB566623#:7?AB>=91778:?A>=3-'5'+552../../+-7>8@=-&&))4.)9CG>DHC<2,,66@A?:D./1+<@B@D(;$4$$5655239.2+((/26*+%(*,%%*%-/1*))(*+-(,/79=GDKDAAA<=>>>5;56//12152/(4:::8683,' +@SRR11410539.547225 547225/1 +GTTATTACTTCGTTCGGTTACGTATTGCTAAGGTTAAACCGGGCGACTACAAACGGAATCGACAGCACCTACTGTGTTATCTATCATCAGCTGTAGTGTTAATCCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAGAGTGTGGACACTTATGAATGTCTTGACACTCGTTTATAAAGTTTATTATGGTAATGCTTTAGATCAAGCCATTTCCATGTGGGCTCTTATAATCTCTGTTACTTCTTCTCCGGGTGTGGTTACAGCTGTCATGTTTTTGACCAGAGGTATTGTTTTTATGTGTGTTGAGTATTGCCCTATTTTCTTTATAACTGGTAATACACTTCAGTGTATAATGTAGTTTAATTGTTCCTTAGGCTATTTTTGTACTTGTTACTTTGGCCTCTTTGTTGTTTACTCAACCGCTACTTTAGACTGACTCTTGGTGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTAACCTTGGCAATACATGGC ++ +$1.%%-,..F@=R:E-5=B(83;55:>94++/F?>:<6)5&,&7=:5/*4<<9=:?=@;8AD>ACBAFEHC@BAAD:;0,%$%).;6=0:BB@:12@&+)2.22=29,AE:@0000=BBC=B:(<9;B@ADA@F88?G@A9<86),<@@,58B<::<>?BAB@79?AHCDA?:@A83HEC=9;A;<%%%#%-8=<==8*++,224729<5+88.+,205%5',6;9%%.36,58+9;;6859<3784.2$69>=,10DDB;13?CB@A9:6A:BED?2AG?;76;;>C?B@J6=44E?ADAA<@D.;2;G@<7C:<<-50=>?0$4)*(&&#$#'(''%*%6.==GDD>=BB591())-@8699=:<:B<68*576676:546400B8=EF;9:;8:5663?2-&)##$$$('*,-/1.1$+&&% +@SRR11410539.605344 605344/1 +CATGCGTTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTACACAGTCTTTTACTCCAGATTCCCATTTTCAGTATAACCACCAATCTGGTAGTCATGTTCAAGAAATAGGACTTGTTGTGCCATCACCTGAAGTAATGACAATTGAAGAAGTTACACTATTGTAAAGGTATACAATAGTCGTAACAATTAGTATACCAGCAAAGAAAATAGTTGGCATCATAAAGTAATGGGTTTTGGAACGGCATTTCCAGCAAGGCAAAGCCTCGGTATTATTCTTACAAAGTTTATACTCTGCAAAAGTAGACTAAAGCATAAAGATAGAGAAAAGGGGGCTTCAAGGCCAGCAGCAACGAGCAAAAGGTGTGAGTAAACTGTTACAAAAAACAACAACTTAGCAAGTTGCAAACAAAGTGAACACCCTTGGAGAGTGCTAGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +((#$'7./44->=>E<;?=98(9:&(9FA9;=4:;<:8542-0*3:-V+6388>;=>F?A@>DEBGJ9?BI?<=?>*@AB%&8:<=8C?HB=HE87=0?D?BGC@DCAECD9-789;B@BCEFCF5+>>>::;,/,.-:62--46I=<-/:PHQB:;:4*68B>>=<15G7>02$&09;57<98;'(7.9B646CFC;>=@GK0.@68464==3,(.=;,34.746?EEEJFGCHE66>88>:DB9'-5.03.+9>BE5@A8166/;87588>88>45(((10:996HN@FFHHADFABAA>BCCAA?@A>BB@A0$'8898),9@@GC<8=;>==@<9<73)*78:74+.>>65//.&'& +@SRR11410539.1359962 1359962/1 +CAAATTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCAACAGCCACCTGGCACATGGCTTTGAGTTGTATCTATGAAGTATTTTGTGAAAATAGGACCTGAGCGCACCTGTTGTCTATATGTGATAGACGTGCCACATGCTTTTCCACTGCTTCAGACACTTATGCCTGTTGGCATCATTCTATTAGTTTGATTACGTCTATAATCCGTTTATGATTGATGTTCAACAATGGGGTTTTACAGGTAACCTACAAAGCAACCATGATCTGTATTGAAGTCCATGGTAATGCACATGTAGCTAGTTGTGATGCAATCATGACTAGGTGTCTAGCTGTCCACGAGTGCTTTGTTAAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCATAGGAGTTCAGCGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAGCGTAACT ++ +)%&%#$$#$%/4?450@BA<1/4FBDHF=>=?;=@@=BDBD>*$&%,''$$&)$$)+..0,'(%..4/5?BB;65?>='#%0.'*4(((=@??CNJ6DEE>7@=B=ABA9;2)?=77@@@K=LM@<><$4;;?DEGCCBA@>EB@<4/;22777;@=@7:=@;=..,/3;:226ACEGF;=DA=AGD;>>;A@@A:953>84>?B<=@@=:;@?EFC;B77>79766799,*))'')(.89;@F49C>>67>?CA;<5A138)7<94465<58:<92<<>:=7293A;6:3,-&($00:::.-06*(.0A>6878197DDGA:0)0:HCE@A@BACIIHEHJJBA?;;535846@A@.'%$&,%'#9'.*/$)&',(68<:;>8ED<=8??A3:@=;=8D:<84;=5@A?:62.,%%()++,78;DI=519@EHBA@554-+)(&(*669541).**%+&%$%%%487?><=97=HG)3C@6BCG<))BCEE:;><>CNIGD@<=AF;=0'/4&&128:>A>>9<@:;;4749;EE69918')765')BBE;;89@B:;BHFB?BFBA@:;>AACCCIE/>,4?AG?>?EE@JE@8?@/10-(4-.<1030$%$%%$$$#%*24AB9415=?AD;=B>+=>61+(#2-.>:::DF?MFEBGDE@F<+5/?<>MG@5)&)''%(,6<<594I@EABC6?BFACI@>>;FCC?A49?=9;=6901HI7%*.9(+<=9AA@A?6BAB;BEGDBC33AA@AB@A@<817434.1-0627==AEEBC(4% +@SRR11410539.1244325 1244325/1 +TGTTGAGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCACAACTTGCGTGTGGAGGTTAATGTTGTCTACTGTTGTAAACACCTTAATAGTCCTCACTTCTCTCAAAGAAAGAAGTGTCTTAAGATTGTCAAAGGTGATAACTTCACCATCCCTAGGTGGAATGTGGTAGGATTACTAGTGTAATATACACTTTTATCACCTCTCTTAGAAATTCTATACCTAGTTGTGTAGATTGTCCAGAATAGGACCAATCTTTATAGGAACAGCAAGTGAGATGGTTTCAATAAAATGTTCTTCAGGTGTTTAAGAAGAAAGTAAGATAGCCATTATACGCTGTAACAGCATCAGGTGAAGAAACAGAAACTGTAGCTGGCACTTTGAGAGATCTCATATACCGAGCAGCTTCTTCCAAAATTGGGATTGCTGTCTCCGATTCCTTGTAGTCGTCTGTTTAACCGCTAAGCAATACATAA ++ +#&&&$#&'-5<>8:B=921DHD9:>B=?>@>;/4;C@8=?5161=:96<8.+/3?CEC:;44=A:=BDH>C@@C=<>@C@=ACBB9;6:822668>GH6&@A21<5;><1987BDC55=,&;?@*/8=:@G=<676+**+>)),(88756)*)5*+4/106,5+'*')/**823AB;6//4/345:;-&8'((727:0+:$;:<<>@BA?@EBBAA@A:@88<54:@?:;:9/89;996<5877<=??:?>G?F=/4<.BA@;<;<;FC:=DGED<=?;2;1=>>:;7)*'-+%''$&255,921/99678;;::;/-,%(2==BA?@?CCEHD==931,##*$$%(,(((''/),+**2;;=,$'%(++%55&'%(*&21/+&:@7A@60-'(1./%&').3-//0366(592?>.901*,*($##($$&0/-,%%('&().%$(,..//2*#$'+*0&''%$10/,,,-.55+(&&/3'%&&,%%/#$%%+(-%(###)-34&)47668:3AF7/;FB4):>>4@?(6)'%)$$&,--'-2+(+42;5.5#%&./5892084226789,,56:<80,)3-,$+/323935757C688,7114'&&-.&.192777>;:;?4<1+*/$-/&'-4<::7:/)=--+(=+>?*$7'/1+#$%'##$/0&%()%&$&,%%#)-0+-('%,)*'''''.16565<95.'($&%"048;.%$%-.-**$((,493043<=;7:356%&5?>;CF:2;6=A::72+064*1&).<<=C>;6BDA@>7722,*$(,/481121<7:AD?DHLEA@=><:BJC3A.%29=@9@3<;9.%$&.28:::9@C<=GE=@FIE=::74>ABC;;HI?@?@AEJAFD+;+0-0;+19B;==9=DCCF?B@C?@D??=89;@::85:?;1)A?6-178:968;?9++9--,?C@GD8;66?A83=7....*3**46)/8:7?@275632110356'<<79611,1)%%:8:DE9//138@BA9:A>?A<=::=<<97;1>=44;>?>C:4@?0)&(.&%:+4/)'*./,8678971ADD>A67CE><75=BCCFADE44CB>GE(;:=95,-)-+,1*,7>AH9=?=99241)(-06:;8:824'+**)'&&$ +@SRR11410539.1714375 1714375/1 +TATGTTGTACTTCGTTCAGTTACGTATTGCTAAGGGTTAAACAGACGACTACAAAGGATCCCGACAGCACCTTGATTTGAGTGTTGTCAGCGCAGGAATTACGTGCTAAGCACTATGTACATTGGCGACCCTGCTCAATTACCTGCACCACGCACATTGCTAACTAAGGGCACACTAAAGACCCAGAATATTTCAATTCCCAGTGTGTAGACTTATGAAAACTATAGGTCCAGACATGTTCCTCGGAACTTGTCGGCGTTATCACTGCTGAAATTGTTGACACTGTGAGTGCTTTGGTTTATGATAATAAGCTTAAAGCACACATAAAGACAAATCAGCTCTAATGCTTTAAAATGTTTTTATAAGGGTGTTATCACGCATGATGTTTCATCTGCAATTAACAGGCCACAAATAGGCGTGGTAAGAGAATTCCTTACCGCGTAACCCTGCCGGGAAAGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTAACCTTAGCAATACGTAAC ++ +##'+46,/(0024>K,2)AA@:<@><3238:()52.1:;@34/C>A?GAEC>76*.+2&&:2>?5>-@H=>CFBDGE,21*E<17.%(&%$$/&-'$%%+')$''65<>:AD?CA/0>@A339-7?>@MPIJCC:=4545)''(*8;@BC=;CBBABD:8/?A?@AB.:<:?8C9:%&$(&(**.1(?;>9:%-*38>B@?9&&48=355//4BD?BA0.6;''@<>=A<:=IF?@,@;BFD()A=7?4:>;@1&$2$#156?;8?KJM=EGFIB9:;07--BFC''(A<@@CC==:939::22.))*BCB836(*-2%---.//04;>=C55@78>AF15;<8;670((#$%''+76()%$%).&&,*'+/9;???<6BDFNG=@?FCA9=4548-*=0714$$#$#&()*++*+-.+()& +@SRR11410539.582859 582859/1 +CGGTGTACTTCGTTCCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACTTTTGAAGAAGCTGCGCTGTGCACCTTTTGTTAAATAAAAATGTATCTAAAGTTGCGTAGTGATATTGCTATTACCTCTTACGCAATATAATAGATACTTAGCTCTTTATAATAAGTACAAGTATTTTTAGTGGAGCAATGGATACAACTAGCTACAAGAAGCTGCTTATTTACATCATCTCATAAAGGCTCTCAATGACTTCAGTAACTCAGGTTCTGATGTTCTTTACCAACCACCACAAACCTCTATCACCTCAGCTGTTTTGCAGAGTGGTTTTAGAAAAATGGCATTCCCATCTGGTAAAGTTGAAGTTGTATGGTACAAGTAACTTGTGGTACAACTACACTTAACGGTCTTTGGCTTGATGACGTGGTTACTGTCCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAACTACATCAACTTC ++ +(#&+%%$,3697@?$*%<<=7AC1?AC=<:A@'2AIGILB@22<;CD?DHB;>68+/*36=<=)2+;CB=BCF?(*=6LC7AE:3;8:68&$#$%&*37:@AEHB:?A))0//39;D=EH3?18>?CBG;H:1(&&)<=?898-79?;BCB?>?449=5DBGDECDB236BH@>?AEEDFFDA@9B=?:,:BC=:;CB?<-.>0=$$0-.7&120866623-$4/-#$&*<@=>B=.-78'.2%+:3CDFCED?L>3=,)39;0?@;6:>@BFGFBF@9:7121368?=?<<4102&>?9DA:6<=<=;@>EA@FA@=A89BB2JGIKDDG<=?>>E<@HA:?ACF0471+)&%+(%%)$(,6<EH@@?778616)(),-,9899;FEC7:1C@/.2%'123'*DFD@?=--<**)=C9<=>A;=7445621.+-('#%#%*+,&&$$$# +@SRR11410539.2126554 2126554/1 +GTTAGCGTTCAGTTACATGTTAACTGGGTTAAACAGACGACTACCGACGGAATCGACAGCACCTAGCAAAATGTTGGACTGAGACGGCCTTATAAAGGACCTCGCTAGTTTTGCTCTCCGGCATGGATTAAACAGGGTGAAGTGATTATGTGTACCTTCCTTTTAGATCCGTCAAAGATCCTAGGGCCACAGCTGTTTTGTAGATGATATCGTAAAAACAGATGGTACACTTTTCTCTCGATTGAACAGTTCGATGTCTTTAGCTATAGATGCTTACCACTTACTAAACATCCTAATCAGGAGTATGCTGATGTCTTTCATTTTATGCTTACAATGCATAGAAAGCTACATGATGAGTTAACAGGACACGTATTAGACAATGTATTCTGTTATGCTTACTAATGTACTTCAAAGTCGCCCCAGGAACCTGATTTTATGAGGCTAAATTTCGATTCCGTTTGTAGTCGTCTCTTTAACCTTAGCAATACGTAAC ++ +((+,/59?/,%&)069%%$'($%'+#$)22<>;?56=76.)+&$&$/./12?<=<@6;4A??1;3=A685C?@:=;@?86227,%%&,-*+%*01)4;7.851&%%&'%(DB1+.78$<*+($)%&'%*#%&/*2))44,'$-%%&,...,)((0112$/6788:8@771$,+%)((<78>640&)00#,)-7@3@AF@1694702*&'&%$(),'78A=@EB6454,7568;3/1-&%$(.0))4)%<(1,$$0(66;=5.17.<;98;6'#/4136/.67<89=>:=;,,.@?@;<686+3@:''.-/.=:;@FF==8:984/('234:8=>$#0+,*-876C=91(,4/.:2145754227DF>FFHD91)%('(00:;>>ABCLIEIMPD7?3@?DD73041CA<<>B=;F=GG@@DD?F;BH@A8/<@<7:?=?FAFE?>A<4<;?@AED?5<=CE+F6>5>B>@5A?27B=JJJ5CD0:+?=9,>@BA<..;:A3*3506--1.=39DF;@D=AA?4+;788;8=45<@>5'*>=HC9:<;84(23BBH=55;6763(0107&(>?=@B@EEOI<=A<=FJHCE?9:;)4888/-(,')&$%696@FAD=;GHD?6@*7+0>22C;B682584/.2:>:7>89-.583?CEA>6FD8:HK:=/=*-@6BG<567-(778=LIM@A<=9,);;>;;8-.-2-3E;ADEADBA<20&' +@SRR11410539.1774309 1774309/1 +CGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCCATGGCAGATTCCAACGGTATAATACCGTTGAAGAGCTTAAAAAGCTCCTTGAACAATGGAACCTAGTAATAGGTTTCCTATTCCTTACATGGATTGTCTTCTACAATTTGCCTATGCCAACAGGAATAGGTTTTGTATATAATTAAAATTAATTTTCCTCTGGCTGTTATGGCCAGTAACTTTTAACTTGTTTGTGCTGCTGCTGTTTACAGAATAAATTGGATCACCGGTGGAATTGCTATCGCAATGGCTTGTCTTGTAGGCTTGATGTGGCTCAGCTACTTCATTGCTTCTTTCAGACTGTTTGCGCGTACGCGTTCCATGTGGTCATTCAATCCAGAAACTAACATTCTTCTCAACGTGCCACTCCATGGCACTATTCTGACAAGGTGCTGTCGATTCCGTTGCCGTCGTCTGTTTAACCTTAGCAATACGTAACCC ++ +$'+&9AD??MC5*+;;/45>==?9?1/04CGHFJ@@>AA::20*55?@?;491::;>::>6:677<0:AC9:7/.4==%+%%3$%.%)$%9;;<;D@AA747A223BC<66274&,&&0073#)CCEBE?7=<9DBFDBBDHHA240<=B6:59633.,1&37;:;BB9AB?A@@CI>@@D;1129450>?BA7;9>>DCLE@=;<<<343533,)-37;8@H@58@AB@CDIFEEGDA@A@DBE8748:;7$$&&);D?><>&$?9:AEECHLLJ>7D59HB>@=>EAC@8*&&&$%9481//8<=DE>C7<:;D?DEKIE@B<;$))))***11G>>>DC5<918;::=>815;=:@?;66021A??BEKGD7*3+')2>:7=D757:<:;A>8A2:6??D77L>>EHE:FD>@=*?93?:55=4;>>.AFFFA@A<5,,-;=9($&=<7,+%%*-&*))+(+1../%$4$$#'.&$'+56=A=C><2,''4##$')))'.++'/.47=AD:>87:9<5881$3*,.400//5+&*'&.'56:=>=<=>CC@8==9=9?>>B<==;?C?IGE>(,,>782**..,(%&&1.59,#),1%,48:<9,')%&%&%*5:962:.&((#$))56/*&%&$#'/,EG>12=?E@<9382/.4.3845<;:5+;@DEEG<8:DIA04@DE><9+8887;>:7:1$*:FHL<>...=;>?>CE@A?8,4;6088=;55DACCCDIFHC8?7;39;)1+,(#(*248*@?EA@B8A?2+-,,'-'39548,#$%##$$&#$#$#"%$'$'& +@SRR11410539.2012668 2012668/1 +CAGTACTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCATGGCTGCATCACGGTCAAATTCAGATTAGCCACATTCAAAGACTCTTCCAACTTTTTTAAGAACAACTTCAGAATCACCATTAGCAACCTGCTCATAAGCTTCTTGAGCAGTAGCAAAAGCTCTGCATATGATGGAAGGGAACTAAACTCTGAGGCTATAGCTTGTAAGGTTGCCCTGTTGTCCAGCATTTCTTCACAAAGCTTGTTTATGTCTACAGCACCCTGCATGGAAAGCAAAACAGAAAGTAGTGAAACCATTTTTCAAAGGCTTCAGTAGTATCTTTAGCTAAGAGAATGTCATTGTGTAACTGGACACATTGAGCCCACAATTTAGATGATGATTCTACTCTGAGTTGTTGCAAAACTGAGAGTAAGACTACTGATGTGCAAGGTGCTGTCGATTCCATTGTAGTCGTCTGTTTAACCTTAGCCAATACGTAACT ++ +##%/.7880%&0A;@HG>==?<<=(9/;+?<>B@A@DDDB@>3CBEE>>;:<:9:4/+.,41269=5:865<===C??AF>BDF.<=>@B:;<=;/3<<>@A;812,89<<==@ABEC<66FG@?:::<:?<10045/4;>?87:9A@B<@8/?@???1AB=<>@@BD8F:36998;5'&.(%'24-=97>A?@CBDMB74@A,97CH3B9A?670(((13639;=6789:A>:20396<852<;;<9:)7=BEDB@66@EA<>>3/*'++-<:9>220921&+1.-767@;:A=@@=:55>>>68*$6?BBDDCC:7)* +@SRR11410539.2293739 2293739/1 +CGGTAGCGCTGATTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCAGAATCGACAGCACCTCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGGAGACTCCGTGGAGGAGGTCTTATCGAAGGCCGCGTCAACATCTTAAAGATGGCACTTGTGGCTTAGTAGAAGAAGTTGAAAAAGGCGTTTTGCCTCAACTTGAACAGCCCTATGTGTTCATCAAACGTTCGGATGCTCGAACTGCACCTCATGGTCATGTTATGGTTGAGCTGGTAGCGAGGCGAAGGCATTCAGTACGGTCGTAGTGGTGAGACGCGGTGTCCTTGTCCCTCATGTGGGCGAAATACCAGTGACTTACCGCAGGTTCTTCTTCGTAAAGAACGGTAATAAAGACTGGTGGCCATAGTTACGGCGCGGTCCCAGTCATTTGACTTAGGCGACGGAAAAAAGCTGATCCTTTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +.(.-,(+'()&$--($(&($4.?;DA9:<''0@ID?B&>22?B972.(&()$(''-389>@B?DE7?<;;;:26<;4(%%(+408=;RO=,2;@GJGF=0565>2*$55;;C7<0><8+=9:CGGE@@?BAB86;:0=/3:6*&,68/=<=AA?<=>?6@>EBG@@;>=98*'#*.+-*136102-1*+*&8294@:979;79/7)%/,++&'<78<@<01)')(*,)8%%.80(3-#''+$(((048&(%+>D:76<>GD2259:'+01012?;99/68@A?G:;6;:A<==80=7=@AE?>C@A>??A===?ABFE>=62%% +@SRR11410539.502390 502390/1 +CAAAATTGTACTTCGTTCAGTTACGTACTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACACACCGCCTGGTTGTTACTCACAATTTTGACTTCGCTTTTAGTTTTAGTCCAGAGTACTCAATGGTCTTTGTTTCTTTTTTTGTATGAAAATGCCTTTTTACCTTTTTGCTATGGGTATTATTGCTATGTCTGCTTTTGCAATGATGTTTGTCAAACTATAGACATGCATTTCTCTGTTTTGTTTTTGTTACCTTCTCTTGCCACTGTAGCTTATTTTAATATGGTCTATATGCCTGCTAGTTGGGTGATGCGTATTATGACATGGTTGGATATGGTTGATACTAGTTTGTCTGGTTTTAAGCTAAAGACTGTGTTATGTATGCATCAGCTGTAGTGTTACTAATCCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAAGTGTGGACAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAGCTGCCAACTCTTCACTA ++ +/&'%$%*')',284:C2+&8A@=5),%-=561FNJHK56;=>@DA><5(;;;5')%*45520+..5::F>;>>=74#$$(-35:-2==>FBBEFC9=;=A?----$&:;=;3;38JD>>$$/G(5FKFIDAGHA<715DGG9BC6%7;<=88DBFC@ACMHFCD<<=<%%9.4)'--AEC?B>JH;@;GFG:DD>=??><<=MH===DBHF9?7ADEEGEKD66DDA?<48=C@B>@BBIA?=A?EDADFDHD>04;>9AC@CFF?AC?BOH67<9AD9=GHFED@C=F:=?@8:B?<=HHRE;<:A@HK5868?;:?=<>@CEE=@E?7@;9777-)-:7+,34>?B227.45CGJCE=@5F9HC;=BCGFDDB@FBAA66>B?<885$&%)+*=>E4;2=ADB@A;@@HC>=917*.552,,'%$&(##$&'$&&'*5%$/% +@SRR11410539.336997 336997/1 +TATTTTATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACCACAAACAGATCGACAGCACCTGGTGTTGTTGGAGAAGGTTTTTCGAAGGTCTTAATGACAACCTTCTTGAAATACTCAAAGAAAGTCAACATCAATATTGTTGGTGACTTTAAACTTAATGAAGAGATCGCCATTATTTTGGCATCTTTCTGCTTCTAAAGTGCTTTGGCTGGAAACTGAAGGTTTGGATTATAAAGCATTCAAACAAATTGTTGAATCTGTGGTAATTTAAAGTTACAAAAGGAAAAGCTAAAAAAGGTGCCTGGAATATTGGTGAACAGAAGTAATACTGAGTCCTCTTTATGCATTTTGCATCAGAGGCTGCTCGTGTTGTACGATCAATTTTCTCCGCACTCTTGAAACTGCTCAAAATTCTGTGCGTGTTTTACGAAGGCCGCTAAGGTGCTGTGGATTCCGTTTTGTAGTCGTCCTGTTTAACCTTAGCAATACGTAAC ++ +%&'''%&**798;2;36/;3/&,4/<;@?@B==2CGGFH1@:;A;?=201/02*0,,;;>@E=:AA?DDLEEL6B<>>?;.)./+/43&@;CE'F>@DD@C=<;8@@4;>=<8<@@OA@AA,;DC+,:,58@A8>LKF?A011255998?+:<<:=557?EG@CBMK=?=::AA>?A@87A9?1<>529+1223134;;=89/+*,+/'197H695:;BB?BC9@;=:0-/+)@E=GC<9;33,$:/8<4:;:8:ACGK5?/7G?ED9(B>?@;=>A@IL9,+(+=AECA09;9=??EE8:=;;A4+++%$$+17788956:<@C;ICD=<;CABAEIAD+(=A9268---.0.*=99?<9=;A<6C9<59A=9?:A19,+*2:4:%$*+,8<@BCDB>?BAEC?58;4345;6/5*$ +@SRR11410539.393872 393872/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGATAGAGACCTTTATGACAAGTTGCAATTTACAAGTCTTGAAAATTCCACGTAGGAATGTGGCAACTTTTACAAGCTGAAAATGTAACAGGACTCTTTAAAGATTGTAGTAAGGTAATCACTGGGTTACATCCTACACAGGCACCTACACACCTCAGTGTTGACACTAAATTCAAAACTGAAGGTTTATGTGTTGACATACCTAGCATACCTAAGGACATGACCTATAGAAGACTCATCTCTATGATGGGTTTAAAATGAATTATCAAGTTAATGGTTACCCTAACATGTTTATCACCCGCGAAGAAGCTATATGTACGTGCATGGATTGGCTTCGATGTCGAGGTGTCATGCTACTAGAAGCTGTTTGGTACCGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGCT ++ +'%##&,'2357:A-0*=BCE<9A<@B==G?@?HIC>CD:@=A>>=31:45417/48;;=>B8C3ADAA<>=<-;*944ACGDCBC@BI?C>75&3724?CFH23;=<88:?<=8<:<8I=@=@BCD.,-B7AF=HC5DK70::C972+678(>@?>:A<9;:=8;;=@A007=?5@:56;;:=?+728<7=8C;88@B48C@;B;;9??.4B@>6011)*)*1*2/./()(%/264:C:B;;-EE=A@=812/<<<:A3B>;<:84,-9=>DEHF6;CHHFADHB7421217-C697,<2;E37CEAEAE9656==@EEGC>BFHDJED<;?,..5><0(-$$%'57E@K@DEIAKE3;;HFF@BK;314%2@?<8$+BA=;76@A@>267$$6D>>BA:*45:8;><511/%%+=57@A>>1)() +@SRR11410539.2377687 2377687/1 +CATTGTACTTCGTTCAGTTACGTATTACTAAGGTTAAACAGACGACTAAACAGAATCGGCAAACTTTCCTTGTTGACACTGACTTAACAAAGCCTTACATTAAGTGGGATTTGTTAAAATATGACTTCACGGAAGAGAGGTTAAAACTCTTTGACCGTTATTTTAAATATTGGGATCCCAGACATACCACCCAAATTGTGTTAACTGTTTGGATGACAGTGCATTCTGCATTGTGCAAACTTTAATGTTTTATTCTCTACAGTGTTCCCACTTACAAGTTTTGGACCACTAGTGAGAAAATATTTGTTGATGGTGTTCCATTTGTAGTTTTCAACTGGATACCACTTCAGAGAGCTAGGTGTTGTACATAATCAGGATGTAAACTTACATAGCTCTAGACTTAATTTAAGGAATTACTTGTGTATGCTGCTGACCCTGCTATGCACGCTGCTTCTGGTAATCTAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTA ++ +''../5378;59L=?;:EF@8::80+%9476''+/:=;5364;3/,(.-'('*/2:<+,5<:$#'('##$&'/360:159D:.//78>@A(321422,,8422@ABE4:'2%%.../:9))377<578-266<8;>:B217=@@@G78;13-,'(*(37;1-&&0/7;6C@>@B,&??>8911::GG5??ADA<='7B/-02:9979>=B<<>D37=<<14;?B1@E;;979;?<@A?>>889?DI>ACHIH@<>;CBF>>>@?@;==96;>C>A8;J6'D:5<:67;B?E?@E;D?%&$*)%&'3799B=>BD0>CBA::>?.@5IIHNHG:D@=;;9:;*%AA793;3.(<=A7E8-.68F?@?>>@DCNI:=;B:4*8;<<:23::863*++47><7A7=I=;C@EEBC=::7CEDFI@B?AA@=>?DDD::8+/))+5;:99;7::B@F256//:;>A;>44;59?@B8=97/C@<=;???=-538ABCCD=>ICA=9*(78>@@<7;GC>++745,;52%*1'225:BA/0>@=19772BDB?==C<=>;ABA=:8>E:*/=84:467B67A?9@CB@7DAD<=CBCACB;A<>=;/49;:66#$$$#$&6A=?>?:>9@A8*-02=@CA=:32.7<;9>>@D:>448;<>F@@???-$+,#)38C?94B:D==95><21=@:*,(5*&7@B@@@?I=@A=;B@;=@@=@CB?65;=>@173528:4+&'7945-.0-,0+5<44;?B>,469++1&'&/*,.+%06<<:E?9B<71>A@<:B@B?9<:46/))*HJ>2=0/+'&($'#&#$#(%%%%$(),;7;<<6:9:459G@@4BE>CB::7-+919//.&&)%$0+.3/0??>26EDB@:FE)%'+,*5;21/<9*/0/3DF=E?:;/1/53'',4:;<<721:97>>53/120&.+-->?;,(&&+./4304-)%()3&''*.34222&&5$$&.,-4>:'&&&02:>=KK923'+04B6=:=F@BC>=<;;;;9'36@;@>>99.,*..7:CCE?:00160=>>>AB9CD@A?=4<978=@E?7,1$ +@SRR11410539.914423 914423/1 +GTTATTGCTTCGTTCAGTTACGTACTTCTGGGTTAAACGGAGCGACTACAAACGGAATCGACAGCACCTCTCTTTAAGATGTTGACATTTGCCTCTGTTGAGACCTCCTCCACGGAGTCTCAAAGCCACATTGAGCATTCTCGCGAACCTGTAAAACAGGCAAACTGAGTTGGACGTGTGTTTTCTCGTTGGAAACCAGGGTTAAGGCTCGCTTACCTTTCGGTTACGGACCAAAGCCTAGATGTGTGATGATCGGCTGCAACACGGACGAAACCGTAAGCAGCCTGCAGAAAGATAGACGAGTTACTCGTGTCCTGTCAACGACAGTAGTGGTTATTAATTATGCTGCGTATGAGTGTGCACTAAGCAGCATGCAGCAGGTAATAAGCCACACAGATTTAAAGTTCGTTTGAGAACAAGATCTACAAGAAGATCGAAAGTTGGCGGTTGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAATAAC ++ +&.-$$(%57:34:*.(3%=>D?478A70.1*(&+#$%%%().89&+*%#*$-03/31%+',.3.534(201/67((/''&((&(%%%'$2+2<=?@EE@;=FD?B;?;8.7>@:<>89:@BCBAM>9=0344$,,+))*&(+5&*7721;.')785-5957-.'*)+%*36<,>678'>:?33=8+5&099<9-&'688>==(*3EFBH52()2-=?@9;:*=;;@>3;93382/575*+/-)4/-?1,<1448<=11401058((/312.8%()%)90/88;?>892*&-1800/('$$$%*)**+.&12%*$-,-27::45.3>?>;FC*'(+&-2%&45/9-))&(%132)&3)+*(1),+'#,./3,.**$&5(784;>BEEC69=LJC/8547<89;:(672%)$$%(/$*015<>86(*$&(# +@SRR11410539.979342 979342/1 +CAGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACGAACTGACTACAAACAGAATCGACAGCACCTACCACCAACCTTAGAATCAAGATTGTTAGAATTCCAAGCTATAACGCAGCCTGTAAAATCATCTGGTAATTTATAATTATAATCAGCAATCTTTCCAGTTTGCCCTGGGCGATTTGTCTGACTTCATCACCTCTAATTACAAATGAATCTGCATAGACATTAGTAAAGCGAGATCATTTAATTTAGTAGGAGACACTCCATAACACTTAAAGTGGAAAATGATGCGGAATTATATAGGACAAGAATAATCAGCAACACAGTTGCTGATTCTCTTCATTCCAAGCATAAACAGATGCAAATCTGGTGGCGTTAAAAACTTCACCAAAGGGCACAAGTTTGTAATATTAGGAATCTAACAATAGATTCTGTTGGTTGGACTCTAGGTGCTGTCGATTTCAGTTGTAATCATCTGTTTAACCTTAGCAACTACGTAA ++ +*'($(-,1264C:B<@:>>D?<889=>68./*03/1&?DJ=F9A31ADD=A??DBDEHCEC=:37?:>?A=A?:-+&+8A8:C=;B?:A2675:@<;;:1++(CD:99>=&-'3(,HDED@;206300JFH@:=?B=:>>C252G/(+(*0>:>@FDAA54<68>55=03,,:?4:*6997+///896-B@B7AFI>@BC00.4?@>ACB??>>3>:&'59C>AD>6>-177=EB?AIJ?>CC,4/.>A08?@?BAF207733694.)8;<>A>>?,,1/.226=7:;::@?@/?-353<>==61/-,52',#(#$##$$&&$/258;95+)$&$)'(1()+84233%* +@SRR11410539.1420379 1420379/1 +TAGGTAGCCTTCGGTTCAGTTACATGCATTGCTAGACAGACTGACTACGAAGCAAGGTCGACCTTTATCACATAGACAACAGGTGCGCTCGGGTCTATTTTCACAAAATACTTCATAGATGTCAACTCAAAGCCATGTAACCCATAAGACAAAATACGACTCTGTCAGAAGATTTTTAAGTGTGTCCTGCTGTTTGGCCTAATCTTTTATACCGCACTACACATTCCAAGGAAGTCCTTTGTACATATGGGAGTGGTATGAGGGTGTTTAAATTGATCTCAGGCAGTGGTTTAGCACTAACTCTGGAAAAATCTGTATTATTAGGTGTATCAACATAACCTGTAGGTACAGCAACTAGGTTAAGCACCTGTGAAAAAACCTAGCTGTAAAGGTAAGTGGTACCAACAGCTTCTCTAGTAACATGACACCCACCTCGACATCGAAGCGATCCATGCACGTGCATATGTATAATAACAAGCGGGTGATAAACAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAAACATATATGCGTAACT ++ +%#'(&&%%&#%$$'((,(-/-)/%%$%&()%&($)&*',''(3/*%&$$('#'%&''*)((#&##&.,4(2+,>>9&+)**/6:8-/*+,ABBE:?9<>83467=D72?*+)()678193'')*&&568,0=@CA:894<986695>:B5+8-,2)0079776234:4)5((-*)%%$&(.((&&&%%56331,*+,)1&*%%&''-42<)1823/60)78:=?CCBAC:83-)'**%(0&&+'222%$(35:=;6826=B=;>-><410-032596--)1.%+)())*.:>A>I:=897/2+.0%%)98?;C=<:<.,+=:11BAA;($?=:<<9;:12,+3*=54-/#544292,$%5.*/.65,2:>?@>DF1-;723'B7;86=;==<@<<&%%%%./69;863040..%%-8669=;942/*$$$%%$%)'*,00.++)((&)%+6/06CHJ>A341;@@AB7..;<>D9>9CAB9:782/)6;1224)35-/')%%(&%&$'$,'' +@SRR11410539.81436 81436/1 +TGATATGCTTCGTTCAGTTACGTATTGCCTTTAAGGTTAAACAGACGACTACAAACAAGGAATCAACAGCACCTTGTTAAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTAGAAAGGTTCAACACATGGTTGTTAAAGCTGCATTATTAGCAGACCATTCCCAGTTCTTCACGACTGGTAACCCTAAAGCTATTAAGTGTGTACCTCAAGCTGATGTAGAATGGAAGTTCTATGATGCACAGCCTTGTAGTGACAAAGCTTATAAAATAGAAGGAGTATTCTATTCTTATGCCACACATTCTGACAAATTCACAGATGGTGTATGCCTATTTTGGAATTGCAATGTCGATAGATATCCTGCTAATTCCATTGTTTGTAGATTTGACACTAGAGTGCTATCTAACCTTAACTTGCCTGGTTTGTGATGGTGGCGGTTTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAATGACATAGCAACCATA ++ +%.,/(*':=?:;>'<7;==58767582$%$(<;<)CIFIL7CCEE=?>@>41;:01$%(,,48:&+46:<:>BBH>AC=>=50G;EGEFBD?B;74*).78<>?125?>D69=C>GIILBCEC4@989%&&$&57;>=118D%*?HF>++,+-'/+08=414GJB=9BCCBBC>A;34445;(*1)+5;A==;=CK@922(,')07@=>HFE6>M8@?B?ED&::IB5A>:=>HD=?==@IDA>4417A=>A@:GIGBA>EGIHC3B>@>>@::&/.//288>>>;444?>FKJJ?87<00+(219<:@@@=9;;;;=46CGE=/7';?@BFCC7GEEGBE?68=8-/;;@?E=B;7524435=>?78/3.<=;=?>98-6C>CI=9?BC@>9GHFIF@;>A?<-31/..99<;AA<-/$*71/99;34=+*)$(/;?677>9E?:;8769568;>=<>?<@8;897'($%&)&&++.&'(-%$$ +@SRR11410539.1886476 1886476/1 +GATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGTACGCGTTCCATGTGGTCATTCAATCCAGAAACTAACATTCTTCTCAACGTGCCCTCCATGGCACTATTCTGACCAGACCGCTTCTAGAAGAGTGAACTCGTAATCAGGCTGGCTGATCCTTCGTGGACATCTTCGTATTGCTGGACGCACCATCTAAGGACGCTGTGACATCAAGGACCTGCCTAAAGAAATCACTGTTGCTACATCACGAACGCTTTCTTATTACAAATTGGGGCTTCGCGGCGTGTAGCAGGTGACTCAGGTTTTGCTGCATGCAGTCGCTACAGGATTGGCAACTATAAACACAGACCATTCCAGTATTGGCGGTGACAATATTGCTTTGCTTGTACAGTAAGAAGTGACAACCAGATGTTTCATCTCGTTGACTTTCAGGCAGATCCCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +&####%+1(36F><7>A?7<92.//$11/0->62)/*+4:>CCE=>@C@9535.%&&000.%4ECEC:1.&1464$*,4?7:@C?000&#*-8;95:.)*2A?@8;=68;4?6:>78,?D;>GD@@;GJ=(=AG=CB>><<:7BA>;<@,.+)8?6;:;.6>6F200/,+062.,)/0&4:9>C;)#*/3,&%.+*786680))*72>?;:822<<8934$30077;98?F5,493..$$##$#&,((',,43>A923355//3692(+'+++%($/>?D>:5'>89=87CD7:+&&($%%*;19:;+.)$%#'$#%#%#/15=>>LG36:ADE<979458<;68CE5313436<67??:?A=;3.& +@SRR11410539.1136118 1136118/1 +GTTGTACTTCGTTCAGTTACACGTATTGCTAAGGTTAAACAGACGACTACAAGCGGAATCGACAGCACCTCAGCCCCTATTAAACAGCCTGCGTGTTTGAAAAACATTAGAACCTGTAGAATAAACACGCCAAGTAGGGTAAGTTGATCTGCATGAATAGCAACAGGGACTTCTGTGCAGTTAACACCCTGATAAAGAACAGCAACCTGGTTAGAAGTATTTGTTCCTGGTGTTATAACACTGACACCACCAAAAAGAACATGGTGTAGAATGTCAAGAATCTCAAGTGTCTGTGGATCTGGACAGCATCAGTAGTGTCAGCAATGTCTCTGCCAAATTGTTGAAGGGGCAGAAACTTTTGTTAGACTCAGTAAGCACCTGTGCCTGTTAAACCATTGAAGTTGAAATTGACACATTTGTTTTTAACCAAATTAGTAGACTTTTAGGTCCACAAACAGTTGCTGGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTGACCTGT ++ +')-343:;;>=E71)0:>?)=67>?@E/.2))73CBGIA4''-*9887/356$*$&%),.79IKIADEECFB->JDDG@ADE;=*91&,9:8;5:99;4719333(';<@A?+,*05/)---.6.3A>:<64=:CHHLHEGF670<.44+%&)8:>C3,(,-3=ADEGCD0?>.6::??;04E8G/720@;>@DB@<+,1,.6=54--%'.7:5=1/;=@6?ALIA+&*DB<>@//63*'#&(*+4<+-6;=:;@A001CA5;===?@514$,2$#&5;975,13:6=404+/7=@>A5211+-FHJ?D5AD<=<98/(++$%&$&&+7&:3;;ECIGHK<;>;FDC>?:9?=6HPIFHEA;A67:K@;;AAAABED8:=<6+%4050CNKE752<113(*=@A<@BIKEGI@B8D?:CAB>9;66ID=?:CBFA84=;?9:=A@?<1),,.5)% +@SRR11410539.2428356 2428356/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAACAGACGACTACCGGCAAATCGACAGCACCTTAAGGATCGGTGCCAAGCTCGTCGCCTAAGTCAAATGACTTTAGATCGGCGCCGTAACTATGGCCGCAGCTCCTTTATTACCGTTCTTACGAAGAACCTTGCGGTAAGCCACTGAATTTCGCCCACATGAGGACAAGGACGCAAGTGTCTCACCACTACGACCGTACTGGTCACCTTCGAGTTCTGCTACCAGCTCAACCATAACATGACCATGAGGTTAGTTCGAGGCATCCGAACGTTTGATGAACACATAGGGCTGTTCAAGTTGAGGGCAAAACGCCTTTTTCAACTTCTACTAAGCCACAAGTGCCATCTTTAAGATGTTGACGTGCCTCTGATAAGACCTCCTCCACGGGGTCTCCAAAGCCACGTACGAGCACGTCGCGAACCTGTAAACAGAGGTGCTGTCGATTCCGTTTGTAGTCATCTGTTTAACCTTAGCAATCTATCTGGC ++ +$-/0+/,68898;.715;5(''--.1$#&$$,8=7-),%'((72251$&#$*&)/55;=<=:@884B,(@(0BE??-.-442-=A:;9:71,1=@A;9>83554003/627?@A@?DD50;<:)-%6/=ACCD:>=I=5580DC??@E;=65;6*0+?:>9?69,/226)42+)((%%#&?@C>>B2?*)(&,.11(+:>>=%*566B>76;CBC@25&"&./+*7B>>>(($$#25;;9;5E;EF@;<00=**@@0;=?ABCFGDD>0<))<11-6>@;7-&)/-%%3))/5((7BBBDBAA9-@<1/BACCA?>8>)+.?=C;060:9=236>;87;778DACJJF>@EBCGHDHE=?HB698>>D??:=B6;8=./:0<,3%('05;?-6;<@665587<;>EEE8IB=..67<;'1@:?:9D::6>;0-','($$$$&**'&% +@SRR11410539.2458380 2458380/1 +TATTGTACTTCGTTCAGTTACGTACTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTAGGCTCTGTTGGTGGGAATGTTTTGTATGCGTCAATATGCTTATTCAGCAAAATGACTTGATCTTTGAAATTTGGATCTTTGTCATCCAATTTGATAGCACCTGTGTAGGTCAACCACGTTCCCGAAGGTGTGACTTCCATGCCAATGCGCGACATTCAAAGAAGAACGCTGAAGCGCTGGGGGCAAATTGTGCAATTTGCGGCCAATGTTTATGTCAGTTCCTTGTCTGATTAGTTCTGGTCCCCAAAATTTCCTTGGGTTTGTTCTGGACCACGTCTGCCGAAAGCTTGTGTTACGTATGCTTTAGTGGCAGTACGTTTTTGCCGAGCTTCTTAGAAGCCTCAGCGAATTTCTTAGTGACAGTTTGGCCTTGTTGTTGTTGGCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAACAATACGTAAC ++ +%$46,83=@A9:<**%).59<62$2.))CGIDG5=<=B9=A>@92<=25<>CB;<;D>F;EH??GD>?B?CC;;FG@BD5655<44DDOHDABA96'$:79BGB;8IGAG;6I->EEHLA@@%%5>>?AD?.))))%+*-08;?IHNC?BA((A67552=>2&557::C@D==;A2,<459:(=;JG?C/6,+31?>@??>=5/9=@CCA=08)*'.3,*:585<9;/:=,<;8/06BC<8813;3?78681:L@H:@A?FD@B@@31/&5'/-27=?@EA89;>:A914A):-3579@<5=<:29>I;>BA;@EHHKCD@E=?AEEB9E;:@A??:54--/<<<5>;8<3)&0*:3.@C:95D:;3,19?D=MDDB@=>64.47>DBCDI@IG:;<;0&'*$$,:;C?774>AC??==?BL,6/4==@>;7621-7<'(5?AG84???B84@9A?=4DG<=99'(%::44?@?41$ +@SRR11410539.206915 206915/1 +GTATCGTTTGTGCTTCATTCAGTTACGTATTGCTAAGGTTCGATCAGACAGACTACAAACAGATCGACAGCACCTACACTATGCGAGTGAAGGGTAGTAGAGAGCTAGATAATAGCAAAATGACTCTTACCGGTACAAGGTGGTCCCTGGAGTGTGAATACTTTTGCATACCAACCTTTTGATAATTTGCAACATTATAGAAAACTCATCTGAGATATTAGTGTTGGGTATAAGCCAGTAATTCAACATAGTGCTCTTGTGGCACTAGTGTAGGTGCATAATGGCATTACTGTATGTGATGTCAGCACAAAATAATCACCAACATTTAATTTGTAAGTTGTTGACCTCGATAAACAACAACATCACCATAGTCTCCTTTTTCAAGGGTGTACTCTCCTATTTGTACTTTACTGTTTTTAGTTTTGATAACCAGTAAAGACATAATTTCGGTAAGTGGTGGTCTAGGTAGGTACTGTCGATTCCGTTTGTAGTCGTCGATTATTATAATAATCTA ++ ++$$%#&%&004-//-'#',)&.,-+/)0,18+06&'-&'+%#$$$$'(&%&#+.)),--)(+)7:<;0>-??=757;7'26---&$$#$$'-34.2-/&$&$.&3*((-)&&%0&2?@>B>BBC?;44000&.,&,%&%&0&)3:=33+,&+;.2-,)&&+./698@65785+,:;778.0+801251%'$$*'())4++;;:B<>?0)C+..4<@;@6+-+(),'(+36;671<7;22+.+3+--3*1+(*##%&&.(15:>B@::5@4-+)&-(.$6;=A17A@BAC;>?3467;;:3329749:;DEA:6;<;CA15'-/''99;;;<<87=<>+,<:45;>;>,1'(/&&)-('=+../(,27.4&(&%(/2304**+)+*%60&%&/0-$*')$,(($'(*&&%)*'')# +@SRR11410539.278949 278949/1 +CCATTGTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGGCCTACAAACAGATCGACGGCACCTTACTACCGAAGTTGTAGGAGACGTTTATACTTAAACCAACCAAATAATAGTTTAAAAATTACAGAAGAGGTTACATGCACAGATCTGTGGCTGCTTGTGAACAATTCTGAGTCTTACTATTAAGAAACCTAATGAATTATCTAGAGTATTAGGTTTGAAAACCCTTGCTACTCATGGGTTTGGCTGTGTTAATAGTGTCCTTGGGGATACTATAGCTAATTATGCTAAGCCTTTTCTTAACAAAGTTGTTAATTACAACTACTAACATAGTTACACGGTGTTTTAAACCGTGTTTGTACTAATTATATCTTATTTCTTTACTTTATTGCTACAATTAATGTACTTTTACTAGAAGTACAAATTCTAGAATTAAAGCATCTATGCCGACTACTATAGCAAAGAATACTGTAGGTGCTGTCGATTCCCGTTTATAGTCGTCTGTTTAACCTTGTAATACGTAACTTT ++ +1'$$&$+&$$&$-(,+$7=5,1&725<:9B56,210&(07161>243)7//@@:<222'1?44))(&''''(,,*0-/$$.%,,(1(2/325%&'%'$'%%)+.*24%%%;>AD<-9,75:516654138557797(.-=6.$&'&%$%0*+2-5+'6>@;B@8:/=65502)*1884=<7.9&8',)>:==4456:203379AA661089@B?71/-/3+7?+100)07>A?A;@6E9..8.1'(12;42..*(*%$,$&%(///5:78%252AFBACA>?=EEE@86/)(/63;>603+)02238498+%''%%))85.1146-,))%&$'**,-574--$$+* +@SRR11410539.666616 666616/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACTACCGAAGTTGTAGGAGACATTATACCAAACCAGCAAATAATAGTTTAAAAATTACAGAAGAGGTTGGCCACACAGATCTAATGGCTGCTTATGTAGACAATTCTAGTCTTACTATTAGAAACCTAATGAATTATCTAGAGTATTAGGTTTGAAAACCTGCTACTCATGGTTTAGCTGCTGTTAATAGTGTCCCTTGGGATACTATAGCTAATTATGCTAAGCCTTTTCTTAACAAAGTTGTTAGTACAACTACTAACATAGTTACACGGTGTTAAACCGTGTTTGTACTAATTATATGTATTTTGCTTTGCTTTATTGCTACAATTGTGTACTTTTACTAGAAGTACAAATTCTAGAATTAAAGCATCTATGCCGACTACTATAGCAAAGAATACTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAA ++ +'&%%,20-/7.&:694@E<2D@IOJK><>$%2GIHHJ7)%)%86550--783=-1/399CJ=>62'BBFHHEAAE@>=A@E:214'/9BD@@B4-%$$565/;B;<467C:<::99B=H?B?709279===7=;1149;BIKGE<>A;1@311;=E>64/))+-*&'9@6ECDGMKE?AE=?5<.0:FFIIBB@DE7//A=13199@@A3<-GA9:?99?=A=>9;73-11;@:4546?=74;687>=DGD:?AFC?>?<@>5=C6<;ABA;=9:<@B?9;F5B@=)BE?A632,'64434-%%'(.+1=?IDGF1/=E7ABAE?1?A<@ONVLF;9J4K@EIF??@:7:75:00405GI11.B>B=A;==;44*1?=DE5-<;EE&-9<44?0?@==93A==EA:<=LHKCAG><@86B:?<=:)*))+028::::;<+,$) +@SRR11410539.175445 175445/1 +CGGTAGCCTTTGATTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGGCTGCATCACGGTCAAATTCAGATTTAGCCACATTCAAAGACTTCTTCAACTTTTTAAGAACAACTTCAGAATCACCATTAGCAACAGCCTGCTCATAAGCTTCTTGAGCAGTAGCAAAAGCTGCATATGATGGAAGGGAACTAAACTCTGAGGCTATAGCTTGTAAGGTTGCCCTGTTGTCAGCATTTCTTCACAAAGCTTGTTTATGTCTACAGCACCCTGCATGGAAAGCAAAACAGAAAGTAGTGAAACCATTTTTCAAAGGCTTCCGGTAGTATCTTTAGCTAAAGAGAATGTCATTGTGTAACTGGACACATTGAGCCACAATTTAGATGATGATTCTACTCTAGCCTTGAGTTGTTGCAAAACTGAGAGTAAGACTACTGATGTGCAGGTGCTGTCGGTCCGTTTGTAGTCGTCTGTTTAACCTTAACTTAATACATGGC ++ +.%&)&&$$#&(&&-/84-6;<8233100/,,()*:KGFI?>>?A>?=>CGEDFA9:==902(%&215:?>?/2DEAECB6@GCC;=BGHBF=:?=C<633336@BBBB@AEFCC@G6C4BAHDCKE5534.'')%#()):<36=9>;DC:3%%+))-11897<./52(743>?@DF>@<7:=:CC6-@DA>?ILHAMI90:DECICED:EA@?B;;<=9=?GI?=3ABC=@/964@HKOB;22E@BB5C/?EEEECDBDFNH+>@A09F=CD?@H@6,<96CF,&'25@BCB&&763%(1716GFAG?3287:>ADB@<;=+)%#$'(22=FG?CD849-2-01>@C@437:>DBF@FE,:(4?:;;939&'(&*%&).(-'14;76=;<:63'''1,.$$$%(1320/%$#$% +@SRR11410539.767457 767457/1 +GTTGTACTTCGTTCGGTTACGTATTGCTAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGCACATCAGTAGTCTTACTCTCAGTTTGCAACAACTCAAGTAGAATCATCATCTAAATTGTGGGCTCAATGTGTCCAGTTACACAATGACATTCTCTTAGCCCCTAAAGATACTACTGAAGCCTTTGAAAAAATGGTTCACTACTTTCTGTTTGCTTTCCATGCAGGGTGCTGTAGACATAAACAAACTTTGTGAAGAAATGCTGGACAACAGGGCAACCTTGAAGCTATAGCCTCAGAGTTTAGTTCCTTCCATCATATGCAGCTTTTGCTACTGCTCAAAGAAGCTTAGCAAGGCAGGCTGTTGCTAATGGTGATTCTGAAGTTGTTCTTAAAGTTGAGAGAAGTCTTTGAATGTGGCTAAATCTGATTTGACCGTGATGCAGCCATGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTGCAACATTACGTAACT ++ +$$%%%&''*)4?*9%+)-)A?HKGC0/.6(>GD>C>81/59@B<777CEB;.4.;<;<;?>?CFBF@E?A7B72@?>=D3+)(+**9A2;6;:>J?@66EABB>?%&)1716@>,,7.?/8BAFFDE@AB?@<7927+01<8$$$/>?)&=@@ABB?AABJI:>A@7?/9>?@D?>A5+($#'(&)**/:;A@40/019)-;;:72B=BBBD@?A77@AB><<2/+,%245;3)354&44A>?8:=>?@229.9:;;E@?CEC::188399'&(&'&&%'#&-.*.,+.>==7,-/59<=>46>88J@?@BB>CEFBJE?EA=?<A?FGEI7E;EFB;/4'$/>?=D:9DAAEF:=GF=A84@:7=3)-,,,.-3783&''&& +@SRR11410539.465845 465845/1 +CAAGCACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCAAGTCGACAGCACCTCACAACTTGCGTGTGGAGGTTAATGTTGTCTACTGTTGTAAACACCTTAATAGTCCTCACTTCTCTCAAAGAAAGAAGTGTCTTAAGATTGTCAAAGGTGATAACTTCACCATCTAGGTGGAATGTGGTAGGATTACTAGTGTAATATACACTTTTATCCTCTCTTAAGAAATTCTATACCTAGTTGTGTAGATTGTCCAGAATAGGACCAATCTTTATAGGAACCAGCAAGTGAGATGGTTTCAATAAAATGTTCTTCAGGTGTTTTAGAAGAAGAAGTAAGATAACCATTATACGCTGTAACAGCATCAGGTGAAGAAACAGAAACTGTAGCTGGCACTTTGAGAGATCTCATATACCGAGCAGCTTCTTCCAAATTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAACCATGC ++ +,&'%%&..768H/1,:;?>C?CBCB:>9&'2B@<24/,%&&'5745.,01$.()(488D?A;F5@=,/:D01((,041;32::5.F@@482(66446:>DDGABAAB@?<>??<9:;E=E>CACC56:II3*@<;%*)=@F@B;;?@475;-)9GG8(<@B61B6BA=:FG?@68@05>@;=;FHBD=762/++/9459;::22<'/@FI?78048<<2B0=:8=9B=DEF>@@;@=@?FB//@A?>H?ACFGBD8712796B>A>E><;=H<;9:9AGC=A+=?;EBFD?NCF9?;/+)40778>@FD=9>89>DBB=?BEBF=GDB1,64.+%&)14>?H?BA6;87AF3.8A6+0)*182?4:;@JFD7*&6=?:5>=:873*+&'$%+&+'(+-&%$# +@SRR11410539.737963 737963/1 +CATAAATGCTTCGTTCCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGGCAGCACCTACAAAATGTTGTTGGACTGAGACTGACCTTACTAAGGACCTCATGAATTTTGCTCTCCAACGCTCTAATGCTAGTTAAACAGGGTGATGATTATGTGGCCTTCCTTACCCAGATCCATCAAGAATCCTAGGGGCCGGCTGTTTTGTAGATGATATCGTAAAAACAGATGGTACACTTATGATTGAGCGGTTCGTGTCTTTAGCTATAGATGCTTACCCACTTACTAAACATCCTAATCAGGAGTATGCTGATGTCTTTCATTGTACTTACAATACATAAAGCTACATGATGAGTTAACAGGACACATGTTAGACATGTATTCTGTTATGCTTACTAATGATAACACTTAAAGGTATTGGGAACCTGAGTTTTATGAGGCTAGGTGCTGTCGATTCCGTTTGTAGTCTGTTTAACCTTAGCAATACGTAAC ++ +%$"#$$%$79<7:GD%(%+9;6@>CHAA779%&4@9?CE92((-6<>@D88=@4:24575-%&*****+**%'14:B;::9&)+88=??:>@B?BGF@CHG?<9BE'B?98>=9;?:=IKKD($8;:=EDAB9/43070&)69367==:@6F4F;=B;6C::DCC../;:4(''''-11DA=GA9:IF?I;@>E910*1.-048A=@;>EHBA=HIE=A668D@=78/A9912955>ABBG@99MHGC=?>68<;@@<3=AGC@<911.(2:;;AA@>;65?BBBAA?DCE955-**,EJFBBC6600256<:;;A@B<852&&'$(%*,,,+*&))*)-.012:DBPD9?@@/1977,89=:@ABA?CD:;:<;88:;8-,' +@SRR11410539.2368368 2368368/1 +CGGTGTGCTGAGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGGCTAGCACCTTCAATAGCCGCCATAGAGGGAGCTACTGTAGTAATTGGAACAAGCAAATTCTATGGTGGTTGGCACAACATGTTAAAAACTGTTTATAGTGATGTAGAAAACCCTCCCTCACCTTATGGGTTGGGATTATCCTAAATGTGATAGAGCCATGCCTAGCATGCTTAGAATTATGGCTTACTTGTTCTTGCTCGCAAACATACAACGTGTTGTAGCTTGTCCGCACCGTTTCTATAGGTCGCTAATGAGTGTGCTCAGTATTTGGTAAAGAAATGGTCATGTGTGGCGGTTCACTATATGTTAAACAAGGTGGAACCCTCATCAGGAATGCCACAACTGCTTATGCTAATAGTGTTTTTAACATTTGTCAAGCTGTCACGGCCGTGTTAATGCACTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGCTCTTT ++ ++#&($'*')*&''(/-2?A;74>:;>54A;<+AEEJLI?:9AAEG?B<:9:5<,1,,,/#$$%$##$#$%(%./..042146,*/)(>;,+,78A?C?<58?;>:>@CIG>=>1401<:<B>BB7:9<99:8967286:BA<=DMD>A?KKJ?98AIIFFC492>:E651*$&),0'*147<3./0@EE;NK:4:A=CAC@BA=>;12+(79BFD?*0&%c?84501:C74-,6*)(60114&)/%&$&368;29=A;=?9D;<=B6;KI;>@<9>A--2-%&&'%&)$%%(',03,,0*0213-&.**,,5=<<@C>9?DB<EC:>@CEGDA634)*+22$+)&&%&+,*14,/:;AB@64271983+2+8=>>>D465;;DAAA@5:5-+*,++(++,,,/976773).%#)(((* +@SRR11410539.1722559 1722559/1 +GGAAGTGCTGCTTCGTTCAGTTACGCTGTTGCTGGTTAAACAGACGACTACAAACAGATCATTTCAGCACCTTTCTGAGTACTGTAGGCACGGCGCTTGTGAAAGATCAAGAAGCTGGTGTTTGTAACATCTAGTGGTAGATGGGTACTTAACAATGATTGACTGAAAGATCTTTACCAGGAGTTTTCTGTGGTGTAGATGCTGTAAGTTTACTTACTTTAATATGTTTACACCACTAATTCAACCTATTTGGTGCTTTGGACATATCAGCATCATATAGTAGCTGGTGGTATTGTAGCTATATTAGTAACATGCGTACTACTATTTTATGAGGTTAGAAGAGCACTTTGGATACAGTCATGTAGTTGGCATTTGCTCACGCTACTATTCTTAACCTGTCATTCACTGTACTCTGTTTAACACCATAGTTTGCTCATTCTTACCTGGTGTTTATTCTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +$%$$%#&'-***,9:HA>67@<35$$)$.1$#$$'$+48.<884238?7<@8A==60(.+,/)*2315;9=-51'B%%*::;=<:;=>?:*''$$&')'+%-B=@?8;:.9<=<822355;?@8''63&%%)%$&',:<=KHB<=AC?60CACNEDC?:9<98;8<98315%%$%''*'$&''$$%&&%*7;9;CC8/)245CE6GHGE?23@>:2:74'(-+17:G>@F?5*&&)*-37*3)$"#.0/()1(%<;;=@=7-)-((+'*,$#(/%#&%$)%&:49@89-/)*$$#"&69?=>?49ADDA:EEAC@GHF><>0+*($$,/:8$###..5=CBAD?I8;AEKMHFCC?>>331+<71>@B?DAEDEB<<+3*3BEBCD62-6*=>@:1)-/0'0##(,88517)1(,.120<>11DABBDA??*((&&/48=@>@23<15>;;:HFDB;@@8:F@<8767+6<3/-><9DF=EB@>-765>E>CDJHIL4B>F12490*15B@?@GABB==7314'))-$8=>>1/0?@<9A@EA668..5'%-1<;9<77'1'%',%-$6+'-'*204/7;DB>@<=89556:45/%((4698A@<9>5212('''>>/374==?=45AA99CAEB;4;5<><439941+0$78:>A66;:0&2ABC@@09;IHDCGBACG3*5'/20.,68<EA<88=714:AC>>:GB@>0-#' +@SRR11410539.1784654 1784654/1 +GATGGTATTATTTCTTCAGTTACGTATTGCTAAGGTTAAACAGACAGGCTACAAACAGATCCGACCAGCACCTACAGGTATTCTTTGCTATAGTAGTCCGGCATAGATGCTTTAATTCAAATTGTACTTTCCTATTAAAAGTACACAATTGTAGCAATAAAAATAAAGAAATAAGACATATAATTAGTACAAACACAGTTTAAACACCAATTAACTGTGATGAAGTAGTTGTACTAACAACTTTGTTAAGAAAAGGCTTAGCATAATTAGCTATAGTATCCCAAGGGACACTATTAACAGCAGCTAAACCAGGAGTAGCAAGGGTTTTCAAGCCTGTCTCCTAGATAGTTCGTGTGGTTTCTTAATGAGTAAGACTAAATTGTCTACATAAGCAGCCATTAGATCTGTGTGGCCAACCTCTTCTGTAATTTTAAACTTTATTATTTGCTGGTTCAAGTATAATGCAACTTCGGTAGTAGGTGCTGTCGATTCAGGTGTAGTCAGTCTCATTTGGCCTCCCGTAAATATAT ++ +*%'%%'$$&$"#&$#'1-000/,'*&&+)*1()*%#&)*$.132.$$'-*&''*,+))$$$-('%,0*43523('%()*')/5573--33+%++++**145<5/-,11.())%02-.'$$$06&)&),-5$,0+%&451&$2245222-2'''),581%&/6)6@B:&4/95354+2:9:9/0.-,%+%+2443.)'&,-,9:86&$&'+).''&,#&'&/**(&--3,3%)$*212:-,)56.%*07;17;/';.((.537<9BEF;387/43.12834::./-3@<;1?@C6:647;/29++***'$'$$(#1,+%(%&*(159:52'(&//*%%%'(-+&'*&('$'$$+&''*'()%%%))--,.,')+%%,$%$%/25A<<=CA?@-.(021&&&%(/)<*+))1,+..&&#%&%(-:A=;686=?;775&&,8001*67@666(,+.*$&$,,).0.'&&&%354/33,/5755;::>50//(((&$&%#$%$%'&(',,**$%''#%%$)$+($&%&$&%&$$ +@SRR11410539.1998471 1998471/1 +CAAGTACTTCCCGTTCAGTTACGTATTGCTAAGGTTAAACAGACATTTGAAACGGAATCGACAGCACCTACACACACCACTGGTTGTTACTCACAATTTTGACTTCACTTTTAGTTTTGAGTCAGAGTACTCAATGGTCTTTGTTCTTTTGTATAGAAAATGCCTTTTTACCTTTTGCTATGGGTATTATTGCTATGTCTGCTTTTGCAATGATGTTTGTCAAACATAAGCATGCATTTCTCTGTTTGTTTTGTTACCTTCTCTGCCACTGCTTAGCTTATTTTAATATGGTCTATATGCCTGCTAGTTGGGTGATGCGTATTATGACATGGTTGAATATGGTTGATACTATTTGTCTGGTTTAAGCTAAAAGACTGTGTTATGTATGCATCCGGCTGTAGTGTTACTAATCCTTATGACCAGCAAGAACTGTGTATGATGATGGTGCTAGGAGAGTGTGGACAGGTGCTGTCGATTCCGTTTGCTCAATCGTCTGTTTAACCTTAACAATAA ++ +0%&#'*+02)-35C<<7<=<*601127?@F?>4GIHFH8;5954'''&$--,2:>9;9??E>EAE?B:3:$-)@<@6603/2C@@5-LDA7:;ADB;BD?B1&#-*661&-:8A7865DBF??ABPGDC?:**<>8GC=889?ALDF:>IHPM@DBEA51@=++B>BEGHAA@AC<7:EGK:A@;;=C69=GB@AE5==;;JEKAEDL<2:>6>?C>@<630116235&&'91-24=JHHD=>BA@08;???@?=;6C6;G.7*----48C@D@,)73/(,8<;C@>?NLA459?=IQD.0>;;5$<78<7EGA6/(1+15'--,*$&#')/3687>@//4,-6:@8&*'+,&'=928:87+18A64AAAC>B=BA@;C0905D><*34..).;DC??@<>C>A=?B>FD5,$%%*+('$.356E=50-(*),&&2++%#$ +@SRR11410539.2476742 2476742/1 +CGGTATACTTCGTTCGAGATTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGTTGACACTGACTTAACAAAGCCTTACATTAAGTGGGATTTGTTAAAATGACTTCACGGAAGAGGTTAAAACTCTTTGACCGTTATTTTAAATATTGGGATCAGACATACCACCCAAATTGTGTTAACTGTTTGGATGACAGATGCATTCTGCATTGTGTGCTTTTTATTTTATTCTCTACAGTGTTCCCACTTACAAGTTTTGGACCACTAGTGAGAAAAATATTTGTTGATATGGTGTTCCATTTGTAGTTTCAACTGGATACCACTTCAGAGAGCTAGGTGTTGTACATAATCAGGATGTAAACTTACATAGCTCTAGACTTAGTTTTAAGGAATTACTTGTATGCTGCTGACCCTGCTATGCACGCTGCTTCTGGTAATCTAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +%#%'(%%,-10;>/+$442192E@ACBBD9:3JMHIJ::&&3,8+40')356=2638?@BC61BFH@@BN@@DD@?BD=ICBQH;;DIIF<==B@*ACA433%&&$-2:;H=)<59;:?'+5BBEHJDD?>9@@=?5%68EF@E@@6?;:.1=4/>6771+$//12/5/'(,%28D9.1678<=DDN<>@CIF:C7B=;@DC=815?>?=>:NK;<@63B>=:4>=;39>?<89238I@:;;9-)(%*<;CA378;E79>BE>B?:;70/+/+1;@=?96A7GIDH@D54=933?B?D/&2'*9;67+2D9:?89;;.0;443;+--4-,8678;8/%&(,6:>;8:@ACC8=CB3);+563:>?A@971/%+,%.3;;6-/,85842521=>978;846/7734438661-% +@SRR11410539.548657 548657/1 +GATGTACTTCGTTCAGTTACGTATTGCTAGGATTAGTAAGATGACGACTACATGACAGATCTGACACTTTGTGTCACACTCCTGTGCATCTATCATACACAGTTCTTGCTGTCATAAGGATTAAGTAACACTACAGCTGATGCATACATAACAGATCTTTTAAGCTTTAAAAACCAGACAAACTAGTATCAACCATATCCTTCATGTCATAATACGCATCACACCCAACTAGCAGGCATATAGACCATATTAAAAATAAGCTACAGTAATAGCGAGAGAGTAAACAAAAACAAACAAAAATACATGTATGTTTGACAAACATCATTGCAAAAAGCAGACATAGCAATAATACCATATAAAAGAGTAAAAGGCATTTTCATACAAAAAAGACAAAGACCATTTGAGTACTCTGGACTAAAACTAAAAGTGAAGTCAAAATTGTGAGTAACAGCCAGTGGTGTGTAGGTGCTGTCAGTTCGTTTGTATGTGATCGTCTGTTTAACTGCTCTGTATCCCGTAAC ++ +&$'#'%&&+%150782?==96750/&&(&&-$'%'#'#$$%%%'12776&)(&&&&&%,%$####$$%&%#$$%(15:8)*.0#$#&'%%''%&(,//89:9<@<=<,.50,:,9'))3)=9%&%,583C?B<:C>D:322722602//./,'&())'))&&&&+#$#%%&%'%)%($(-/+.341.*/130-'(%&$$.552)386DFGHD;?;7237,.==56613--0/4+0),7821-&&,.($%$(**$'&(.78-(.;=BCFLHFC=A;*((20..3,%-$'.,-+243'$''%%%#160.A19=;6)&$0#$*'&$#%&&(+'**+% +@SRR11410539.2286820 2286820/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAGGCAGACGACTACAAACGAATCGACAGCACCTACACTATGCGAGCAGAAGGGTAGTAGAGAGCTAGGCCAATAGCAAAATGACTCTTACCAGTACCAGGTGATGTTCCTGGAGTGTAGAATACTTTTGCATACCAACCTTTGATAATTTACTAACATTACTAAAACTCATCGAGATATTGAGTGTTGGGTATAAATGATAATTCTATAGTGCTCTTGCATGGCACTAGTGTGGAAGTTACTTAATGGCATTACTGTATGTGATGTCAGCACAAAATAATCACCAACATTTAATTTGTAGTTGTTGTACCTCGGTAAACAACAACATCACCATAGTCACCTTTTTCAGGTGTACTCTCCCTATTTGTACTTTACTGTTTTTAGTTACACGATAACCAGTAAAGACATAATTTACTGATTAAGTGGTGGTCTAGGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTATTTAACAGCAACTCTGTCTTT ++ ++35)6/K950<9=EC@EGDE<:A//3D>18'%4.20.979507;=7+3$:::=?:B4AAA?9,'':?B<<4678@=8C::3@9B:>;96.25:>C=A@?AB96-/DEFG<>:?A:;3%$$(,,.44,%#)#)+),+$%$,-*03122++146;9@B322@?<;92,26><@@:;(57:BEEFIABBBB=;8;><==66(+124+.+,$)(83:GDCI=GC./)%0*.3'+*'5/3%($$%$$(%'*==<.5DCDCB@@20;77@@>=402$)++158>FC?B>E@B?CA>+8IA889@>C>597>.0100./$$)&&03.,%%%(9;:<541178QL2+2&0@@>;D?8=5530@A>A1-*.3=C?;<>>;:80$%261&+6;>A=?E>-1=?A<8D=?>4545(##&+%23*-5:9:>97562(-/20241/.)&&11-/0/69>>@32335/877)$.,*,*+'$%,+&)*0,32/2( +@SRR11410539.1849204 1849204/1 +CGGTGTACTTCGTTCGTTACGTAGTACTAGGTTAAACAGACGACTAAACAAATCGACAACACCTCTTCTGGCCCCGGACTGAGACTGACCTTACTAAAGGACCTCATGAATTTTGCTCTCCTTATACAATGCTAGTTAAACGAGTTGTTGATTATGTGTACCTTCCTTACCCAGATCCATCAAGAATCCACAGTTTAGCTGTTTTTGTGATGATATCATTAAAGCAGATGGTACGCTCATCGATTGAACGGTTCGTGTCTTTAGCTATGAGCAGCGCACATAACATCCTAAATGGGGTATGCTGATGTCTTTCATTGTGCCACAATGCGGCAAGAAAGCTACATGATGAGTTAACAGGACATATTGAACATGTATTCATTATGCTTATAATGATAACACTTCAAGGTATTGGGAACCTGAACTTTATGGAGGCTAGGTGCTGTCGATTCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTA ++ +.%('&&$()*&/00-+.0/($%%$$$$)-'5@?;=61%%)$319(,-$.,/43,-%/(),--.*$$$#$#$)+,-@,2<@9;<7*)32/010423023'*##$'#%13531*$)66672-&%*$'&$')+27=-.68569:79.3.2255.2+&$&(39867%))//+&'#(&*)(/12423433()%(42,-*)0'&++-(%.)0*..0.,1'(+)#$$***6899;2-6+0446/389410?97-&%#&&$($&%.&%++,$$#%)--)%$&(212.*$%)#%$../1-1125'3263-123$$)#%%$%&+)%686168=?A=893.<93'#''&($$&'*,.84/3*'+/11.,--'../335A==%%2222,-(5-,/2())(+()'*$**--*78'+'67:5.7+C?>C*$/1),-23=>E9;785:548728;9'(..-*&$$5.&&/,&& +@SRR11410539.2113941 2113941/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAGCAGACGACTACAAACGGAATCGACAGCACCTGGCACATGGCTTTGAGTTGACATCTATGAAGTATTTTGTGAAAAATAGGACCTGAGTTTACCATTGTCTATGTGATAGACGTGCCACATGCTTTTCCACTGCTTCAGACACTTATGCCTGTTGGCATCATTCTATTGGATTTGATTACGTCTATAATCCGTTTATGATTGATGTTCAACAATGGGGTTTTACAGGTAACCTACAAAGCAACCATGATCTGTATTGTCAAAGTCCATGGTAATGCACATGTAGCCAGATTTGTGATGCAATCATGACTAGGTGTCTAGCTGTCCACGAAAGTGCTTTGTTAAGCGTGTTGACTGGACTATTGAATATACTATAATTGGTGATGAACACGAAGATTAATGCGGCATGAAAGGTTCAACAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +$%,.+0/;=@<=EE@88AA:*$##"'66;./2GJC>>,.,--.$$-3/74:>504>>;A:A84>BBCCJ<;=;AEH8/%'((/-7@BCBBD?E@=.??BAB?CDDD/9<+/(5:42-)'&#$#$$%'58A=?@D<>CDA0+5+0+>6=;98A<<899HF>A@AF;:=?624D==B<:;:.&&+.3.9=AB<><586'2@DDCF<>@;A>BCCC;@?@AIDIIE;;>?@G67:>EFD;115218/177=B>IJB=?*+><@9777?<;>CFE<2<&(%%'(-5:/0;;>?@?@<=;;94+*')(048C;:@@F;==<7>68:64.&&9B@:<-5/894224*)'/,,)@866:GCGDEAA@A<93:721:3--2%-//999533/.1'5C@?D--.:*5'79:?=@BEF?&',$&<-155=?3+<<??A@322134431&&% +@SRR11410539.1457535 1457535/1 +CAGTATGCTTCGTTCAGTTTCATGTATTGCTAGTTAAACAGACGACACAACAGATCGACAGCACCTTGATTTGGTGTCAATGCAGATGCAGTATAAGCACTATGTGTACATTGGCGACCCTGCTCAATTACCTGCACCACGCACATTTTGCTAACTAAGGAATTTTATAAGACCAGAATATTTCAATTCAGTGTGTAGACTTATGAAAACTATAGGTCCAGACATGTTCCTCGGAACTTGTCGGCGTTAATCCTACTGAAATTGTTGACACTGTGAGTGCTTTGGTTTATGATAATAAGCAACATAAGAACAAATCAGCTCAATGCTCTAAATGTTTTTATAAGGGTGTTATCACATGATGTTTCATCTGCAATTAACAGGCCACAAATAGGCGTGGAAGAGGAAATTCCTTACACGTAACCCGGAGAAAAACGTTGGCTATCGATTCCGTTTGTAGTCGTCATTTAACGCCAGCAATACGTA ++ +%$%$%$##%((391,%($&%%#$$$'%'%$$%&%(+--4246-.*+&)(()%%99:78@9==ACEBFG=*/574@893018--,((&(+*+*+,..,2589,;-+B68:/05:674256>9;2413088:6:.:;;@@B;4---*(%(2++00''%)%$$$$$#%#$$+)575206;>=E,:<96-)-(,,''010/0631+,/2//2886:?%%7-.1-(%'6:.2-)2568<>>:5>49:,+/00$$*,,245356@D=?>A>622/'+--2>600199=IG><==><35)())%%&)))&'$('#+-70726?<=//**(*&'&./)%$$##85=7899:;<;:=:89;(4:;5:0/.0-/9::8@?;?22:<:4+-*+(++*$%$&**1*+*'&-41/-,%%(,,+530($%%$%%$#%$%5;:EC6;;7DMIHLD7989:=;?=C96;88ADBC?9&,0*>88:<;89136;?504*;-/LG7=/+'((;<59*#('652'@:=@=0D?@D4=>?;99A@B@DDEB;;C>B=>?BAF6(&,+86998;3::'E>9960<954+2/12=EBBBSOE?8<=EGLAC=@A9;EHE8*/9-77A?BDC7DCEC<==FAC@7@?494;BD00>=>>C><=0557ABF??4;F88GCF=155;9;@;99;A<@?;=??B6<993?>=ACDB0*(..//@BB;GF8>@EFB@BCIIKFF?@?@B@DDFGCKFHMB.,5A>88H6>7@<>EDBEBKCFEHGC>DE94C:A6.===><:<<:<8CAACD?ACCBC?9;:=>:/454%%.',,**9<9<8'%%(% +@SRR11410539.1855281 1855281/1 +TGATGTACTTCGTTCAGTTACGTATTGCCTGGAGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGCCAGAATGTCACCTAAATCAACATCTGGTGATGTATGATTCTTAAAATATTTATCTAACTCCTCCTTGAATGAGTCTAATTCCAGGTTGCAAAGGATCATAAACTGTGTTGTTGACAATTCCTATTACAACATCACAGTTACCGAACCTAAATGTGTTGTCTGTAAGTAATGATTTGTGGTTCATAAGAAATTCACTGTGTTTACAAACCAGTGTGTGCCATTTGAAACAAAGACACCTTCACGAGGAAAGTGTGCTTTTCCATCATGACAAATGGCAGGAGCAGTTGTGAAGTTCTTTTCTTGTGTGCAGGGACATAAGTCACATGCAGAAGACTACACCGTGAGGTGCTGACTGAGGGAAGGACATAAGATGATAGCCCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAGCCTTGTAATACGTAAC ++ +#%$(*././/58<=,)-)+026:<<=::;=48$):+834--%(&)389E=@=C:>>=<6'442/1.)69:?.?6B85@45CBA9284916/047278=78@@;B8@@DC6.*4%%'))'9;@61.*EE??A@<<)*>;CF6>4443.(',@?>=767&0104.*))/196;=:E@HIB4C@BB8&7B>BBCCC:@5C>;BC55=8A6;A?:952/3/(,3*9531056;<6KG?(<3=7;555=?::346=A4=340*(%/165=?A=<74/0,*,=>><<=4,*+$)&'340>:<+,?B@@<88;7>@>986><43<<9=:8KD8?;AFE43--75/1>6?>>02'*+()%%-.26500*($ +@SRR11410539.2360387 2360387/1 +CAGTATGCTTCGTTCAGTTACACGTATTGCTAAGGTTAAACGAACGACTAAACAGATCGACAGCACCTAGCACATCACTACGCAACTTTAGATACATTTCTTTATTTAACAAAAAAGGTGCGCACGAGAAAGCGCAGCTTTCTTCAAAAGTATAAGGAAACACCATTAAAGACTACACGTCTTTGAGTGAGTACTAAGAACCAAATGAGAAATGCTTTATTGGAAATACAAATGATATAAGCAATTGTTATCCAGAAAGGGTACTAAAGGTGTGAACATGGCAAAAAATCCACTGAATATGTGCTAAAAAACATCATTAGTAAGATAAAATGTCAGTACAAGTAAATAGCCAGATAAACACCAGGTAGAATGAGTAAACTGGTGTTAAACGGAAGTACAGTGAATGACATAAGGAATAGTAAAGTATTAAAGGCAACTACATGACTGTATTCACCAAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGAACGCTGGGAAAGCTTTATGCACCGTAAC ++ +($*((%$..2>=L@A:<>5-$'0-233710/%%-=F?771,'&.44/1%24'.*+4.4<>765=6@B32,*+463?99=98-.34;;97@<:<@8C*5EE9,''%#%&'1$(.,3369::BC.-;78??:);6+98,'$')&'%44)501&.2&'*,)/))*17<219;;1''*$''-6=@<9:<982*&-+.(;;=C>?>./>:;,D@AD@E::3+&%%$$$%)***)&%$$'%''%&))1%'*)/1*2'-81+-28=>78815;>BB??94#&$&%%''97:A453<786)?87:GK44DA>3-5,45?EE?>BEDDAG?A?:9%*..29BA=BDEOD8::??F32663.*07,1$$$##&$''%'%'$$#$%#$$%#$$&#$# +@SRR11410539.1444645 1444645/1 +CAGTGTACTTCAGTTTAGTTACGTGTGCTAAGGTTAAACAGACGACTACAAATGGAATCGACAGCACCTAACCTTTCCACATACCATAGACCCGGTACAGACTGTTTTAAGTGTAAAACCCACAGGGTCATTAGCACAAGTTGTAGGTATTTGTACATACTTCCCCTTTTAAAGTCACAAAATCCTTTAGAGTTGGATGATCTCTCTTGGCGGCAGCTTGGTACAGACAACACGATGCACCACCAAAGTTCTTGATCCATATTGGCTTCCGGTGTAACTGTTATTTTGACCAGTACCAGTGTGTGTACACAACATCTTAACACAATTAGTGATTGGTTGTCCCCACTAGCTGAATAATCTTTGGCGCTTTGGCAGCATCTGGCAAAGCACAGAAAGATAATACAGTTAGATTGGCGAGGCACTTCTGTTTGCATTACAGCTAGCCAGACGTACTGTGGCTTAAGCGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATGCGTAACT ++ +,&)#%*'**,&#'&((%**/$$&-$58<;A=0;AC@C==A?F::<>A>)9=?>CEBEICABAGCH?8:6,%%$$%$%(23<>:?@=872..37=@78;95*$$%''*-/+-*)&3$'&(&&#$)#%&'1.///6::9:;B;::8,=,,@942;=;:0*(%($(A@>>767)93:,37845G:DBAACF??>BBG6,--((9:BCACC=@4+71-/95BCABF>:;??@CF?6-+69A@BD9:CEBDD9;>><788=8>>;:5:8((0563+1"%-*,+'(-14)0*''0+/1&%&)(*'$$$%)'.+45;>3-&$%%.*.$$)).-0.'%$$+#$%&(+&.0/'+$%&$+&'%%'&%%126+;<3:;6211%%%&'($-.>;<@=8=9D?@2$C>@:@?BDHFHAB1IG<:8A=?<=23799788468'(;DFH5/7/16:><<:JCDBB@BC:0:/;:===22==DCA/C.>?H505?@NJHC>C?GGE<;B?BC=43:>B;;576699'B>D@E>A;44:>=14@@>=373?FI:.(++-2>BHFA<=EE?FAFB79CBA@?B@:,@??)EFFDF@:?C?@A(:8GA)19>GFB>;>=:;/,**/0B?;;:,155B?D<=?25'(<=>HAH?B6?3>9@A;@?@;/(>:68-16,4'42379=@:94-10)),(.2653)+-:>;3/-&)***55;@:>A<>A>>=EFEDD>78E?;CC@0+2,/?>B@E=@A<9<70@11CFIBJGGHIDFDC@CDF32;92/:6@B@585A3=><>@998;><6A6<>3CD@FDB88ABBE8;013@513*45:-*4,2,07==43/41:LG?B><99><855629DA460=9:B=/:A89??AGCACC>CBAJ?3>AADE=@A?B@?B;>;D@GEB9;98=:<;?DJL95CEHB@A@7::,-0=8C;;B6>09969&559;<88,,1334@=;86;C87;:2282257;=5@B@>=@2?>D@D;>A=9:12>567')*/-*5;=9///7++)3=>A;;$$75.246932FLB=FGEC;=B=?<443DF>>@:?A=44/-/&8997<7AC:BAB6'%.7:F>B?<<>C:/03@=FBKI?:?%4&&EH@E:;:D<=4***))()47=48341-+&+'(*'0'.6563977A,?;A@=333,*2233AEEB=96'%90C@BB@?@C@5C;>?HAKC52=:7=9?BAD@CA:0**'018887302#%$ +@SRR11410539.1623861 1623861/1 +CATTGTACTTCGTTCAGTTACGTATTGTAAGGTTAAACAGACGACTAAAACGGAATCGACACGGCTTCCTTGGTATGACAACATTAGTTTGGCTGCTGTTGTAAGTGTTATGTTCAGGAACTTCAAACCATCTCTTGCATTGTTGATAATGTTGTTGGTACATCCATTATCCAACTTTCTAAGCATAGTGAAAAGCATTGTGCATAGCACTAGTAACTTTTGCCCTCTTGTCCTCAGATCTAGCCTGTTTATACATTTGGGTCCTTAGCTTGATCAGCCATCTTTTTCCAACTTACGTTGCATGGCTGCATCACGGTCAAATTCAGATTTAGCCACATTCAAGACTTCTTCAACTTTTTTAAGAACAACTTCAGAATCACCATTAGCAACAGCCATATAAGCTTCTTGAGCAGTAGCAAAAGCTGCACTATGATGGAAGGGAACAGGGTAACGCCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +$#()053./1/,4-/'56;;93<323*)$%+>55;=;7031320('144/1/16;:95/-*+$'#$$%('**.,*)().*)*$$'*::AB1:>E=<=;34*)+,)3%$%#($4.'$'+*+$(*%$&'&'+%*,57637;AC4?B<A883'$..*++@8:9=?A>=@FA@8::<>)-%*((&&.4615=HCA;93(;;C6--.-5;BB8FBD241AAGFDC=?:C4:--$%*357376><834012'4//1532)$$)*--2$$6@D@=<<.*2>>67==9):=<.93&;:BCAE3378.?708,'0-,&%&%'&/9<@E=??<8512:<>HHH;;6666.:<89BDCC<41$, +@SRR11410539.157302 157302/1 +CAAGCGCATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGTTAAGCGTGTTGACTGGACTATATGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTGTAGAAAGGTTCAGCACATAGTTGTTAAAGCTGCATTATTAGCAGACAAATTCCCAGTTCTTCACGACATTGGTAACCCTAAAGCTATTAAGTGTGTACCTCCAAGCTGATGTAGAATGGAAGTTCTATGAGTCACTTTTGGCCATAAGTGACAAAGCTTATAAAATAAGAAGAATTATTCTATTCTTATGCCACACATTCTGACAAATTCACAGATGGTGTATGCCTATTTTGGAATTGCAATGTCGATAGATATCCTGCTAATTCCATTGTTTGTAGATTTGACACTAGAGTGCTATCTAACCTTAACTTGCCTGGTTGTGATGGTGGCGGTTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAATACAT ++ +-&&$$#$'''*58?AF./$)()%($$%+.14851+=AGEH6=117487:976=<7>36-7>;?B?=CEFEEDGBDC-.CA=BB?:=;>A;<2,,&%&)&&'$#"$$)54./.4=>F==FCHB:?67A:8>=4GEAAA7:??A=D;BFGDDFA@=5234366.5;D@AG?<@=@ADD>;;;73.)+#%%-.AAA=6F<=>/5AC>3.%#%$%$$&&()*+''##$,#&%2259CECA?A@AA@@<<;;<:2588;'16312+-59>?C;=>31855;>11A@99BBBAICC?H>,..36=6@67>8453<><;G@E89?EDCGAC=7915'+15E>>F89>29FHAAJ;?E?>B<6@>DHB=<6A@HCCCB;>87879787))#$#%*,-..,' +@SRR11410539.802415 802415/1 +GTTGTACTTTGATTCAGATTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAAGGACGACAGCACCTCGTTCACCTAAGTTGGCGTATACGCGTAATATATCTGGGTTTTTCTACAAAATCATACCAGTCCTTTTATTGAAGTAATCCATCATCACAACAATTATATGACCAGTATTTCTTTTAATGTGTCACAATTACCTTCATCAAAATGCCTTAAAGCATAGACGGGTCTGCCATTGTGTATTTAGTAAGGCATTGACGACCATATAACGGTACCATGTCACCCGTCTATTCTAAACCCAAAGAAGTCATGTTTAGCAACAGCTGGACAAATCGCCTTAAGTAAATTATAAATTGTTTCAATATTTCATGTTTGGTAGTTAGAAAGTGTGTCTCTTAACTTTAAGTAAAGTCAATTAAATTGTCGTCCTTTTCTTGGAAGCGACAAAGGTGCTGTCGATTCCGTTTGCTTGGTCGTCTGTTTAGCGCCCGAAATACGTAGC ++ +'012-))**)*&()&&&'=>=<9/--67)$'01-?KFBDA<>>>=321)%*+.16$%,+#$$22=9@B?>>*>EABAA7=3858?8<>9@?=:CG?A5??75.,3>9=>BECK?79$&)89>@;;755895=00++1342212+'$**,''4)'7:4?;?559-.-,$$&*(($%/)0289?686550322;63;33;?9:/;:B<@<78>?=J=@==>??B4.7-15756%'::?=?BB=@E645*'36/)45233+'%$(.+(%%$'%&%&$$%&*)'78@??;??>A@;8<.)56&)56+.,,EF7/:8@?C=@<=>?9??:879GB;;9+*')&%-###$$68;??;33:>A37DFI=:;)0##/&4:A<=56A?455+$%$+&$+-'2;>/934@BCC>=((+&#%'0%')$'->@?B6;:<@8:46))1''')$%'&+&'(2<=;@@,/?A??A<7>?;;9$(09:.&$$&+/5:746,+%&$$$$$$%%%$$$''-,)''& +@SRR11410539.991348 991348/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTGCAAACGGAATCGACAGCACCTTGTTTATCACCCGCGAAGCTATAAGACATGTACGTGCATGGATTGGCTTCGATGTCGAGAAGTGTCATGTTTTACTAAGAAGCTGTTGGTACAATTTACCTTTACAGCTAGAGTTTTCTACAGGTGTTAACCTAGTTGCTGTACCTACAGGTTATGTTGATACACCTAATAATACAGATTTTTCCAGAGTTAGTGCTAAACCACCGCCTGGAATCCAATTTAAACACCTCATACCACTTATGTACAAAGGACTTCCTTGGAATGTAGTGCGTATAAAGATTGTACAAATGTTAAGTGACACACTTAAAAATCTCTCTGACAGAGTCGTATTTGTCTTATGGGCACATGGCTTTGAGTTGACATCTATGAAGTATTTTGTGAAAATAGGACCTGAGCGCACCTGTTGTCTATGTGATAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAGTAACT ++ +(&))*));BDDCCCB><>H@CDB946'78<..,-);99?>=?C=E:;;35:6FBD:<355BE?BADAC9FG?:?853++:B<7;13*$%%0:62$'.7*4A@9>:/,&$)),)-C6>>=?>>663?;:=&A8;I@80+5452D>EGDDA>2)9371+122798=G-;,>15:;9CA:?>B1CB8AFH;<=@@@@:9B@GC?,/50'>')'(:8;=BF6=89679;;:14*'&&3).)/9@DB?B<;A=/C@:;'$%'8>45.)@E=CA)*(0?D@=CC''>>D;8?@<=B@CFC411EA@;9,3577DF:)79;<=/=.EA1F/:G9;8<8B?>'788@DDEJE@@89A>?67E@A,47;@<<@A;57>B>2AIIEFLH9>99KFI?CAHF?<:00D@BC=>;D%;D;;?A>56DA>9:7;@?=<<:;CDNHB@9;=C856A;><>A@BDE@@@>;:B;<=;;?@AB-<('41'* +@SRR11410539.1845353 1845353/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAACAGGAATGACAGCACCTCCATGGCGAATTCAACGGTACTATTACCGTTGAAGAGCTTAAAAAGCTCCTTGAACAATGGAACCTAGTAATAGGTTTCTATTCCTTACATGGATTTGTCTTCTACAATTTGCCTATGCCAACAGGAATAGGTTTTTGTATATAATTAAGTTAATTTTCCTCTGGCTGTTATGGCCAGTAACTTTAACTGTTTTTGTGCTTGCTGTTTACAGAATAAATTGGATCACCGGTGGAATTGCTATCGCAATGGCTTGTCTTGTAGGCTTGATGTGGCTCAGCTACTTCATTGCTTTCGAACTGTTTGCTGTTTACGCGTTTCCATGTGGTCATTCAATCCAGAAGAACTAACATTCTTCTCAACGTGCCACTCCATGGCACTATTCTGACCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +,+-.441:?3:<>8<3>@:888>?451BDCDF<@9:?9<<9;>:;94+'02)/22>:6<=A<;D7<<=///99;52=<<4;45;:;?;:72532011+.4()'--:E?6-*9;@466/68<>05)7;853-47:+).+-*/HA=:DD66HEFE9=66@@4442FCLHE<89?DEBCDD776:A?@??VF766A8@6:=@A<;;7/=A55/032'%$06>;EDB9A=789%4B>?>DB9B7;>?420099<=8A>D@/08/1.))078C@:A2>>??AEFMKB99?90,-.*55792?&1544/75/9=;&&-?5?D79@B?70/27=:BA>%#%$$&0+-7:5>>)-0+.+-*+6;@BAA56%%<54)'$&%%,67;>??>GC;7=$%*%>6::+)?9=:C=>C<7?HHC>283$+++',955C>9=@>?9.26A?JBF==9:;=?<=9;>CCDAECAABAA:7$'# +@SRR11410539.298486 298486/1 +CGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTAAACGAATCGACAGCACCTTCACGCATGATCGTTCATGCAATTAACAGGCCACAAATAGGCGTGGTAAGAGAATTCCTTACACGTAACCCTGCTTGGAGAAAAGCTGTCTTTATTTCACCTTATAATTCACAGAATGCTGTAGCCTCAAAGATTTTGGGACTACCAACAAACTGTTGATTCATCACGGGGCTCAGAATATGACATGTCATATTCACTCAAACCACTGAAACGGCTCACTCTTGTAATGTAAACAGATTTAATGTTGCTATTACCAGAGCAAAAGTAGGCATACTTTGCATAATGTGTCTGATAGAGACCTTTATGACAAGTTGCAATTTACAAGTCTCTTGAAATTCCACGTAGGAATGTGGCAGCTTTACAAGCTGAAAATGTAACCAGAGACTCTTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +%%%%),,45728=3*%4;@C?;FDEA<)8%&=FJIGL=@@>>;634*130/&%())*88?;DH<=FB?=9689761&&%##%(&$'*-)5,,-/0.00B7@AECHA;<9B69>%&AEE8=75(219@-7-@AABGFGA>887=?BD@8K>7BCA;AF:7CCD88>>E???/@&=?<JJ8C:;97(45/0.--',:A@ACEE<&',969==2?<8:B68+3())))89>?:?=:+>:@@?=98(+('$54??A?A=>6=07??;4;::=:965458363,8%2<;88C>;..$' +@SRR11410539.1428534 1428534/1 +CGGTATTACTTCGTTCAGTTACGTATTGCTAAGGATTAAACAGACGACTGCTAAAAATAGATGTTGGCACCTACAGGTTCATCTAAGTGTGTGTGTTCTGTTATTGATTTATTACTTGATGATTTGTTGAAATAATAAAATCCCAAGATTTATCTGTAGTTTCTAAGGTTGTCAAAGTGACTATTGACTATACAGAAATTTCATTTATGCTTTGGTGTAAAGATGGCCATGTAGAAACATTTTACCCAAAATTACAATCTAGTCAGCGTGGCAACCGGGTGTTGCTATGCCTAATCTTTACAAAATGCAAAGAATGCTATTAGAAAGTGTGACCTTCAAAATTATGGTGATAGTGCAGCATTACCTAAAGGCATAATGATGAATGTCGCAAAAATATACTCAACTGTGTCAATATTTAAACACATTAACATTAGCTGTACCTATAATATGAGAGTTATACATTTGGTGCTGGTTCTGATAAAGGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +7%*10/1,>EE>;F1686BC:252:6564.0-:;9,(%$%(&%%&$%$-5599:98DJCB=6D9<>7E9071@>DFFAOOFBDE>=AA=>?<@DDG9GF??G0>>?DBHCE1236<=<;;?@;9:0--4;>C7?8=>,AMOB=?1249?52714,0:::A@9><55IIG=@BCBBD;4=G?@CCFAC<005594-*+**8:=AFG@763,>6-'?*60.+0'65F=BGEE><%*4ABEF59?<%%85=AD<<9''03B;DBGJI>@8:5'''%*.3?DC=433*&(;>?=<4=620"& +@SRR11410539.1249289 1249289/1 +GCATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCGGTAATAAAGGAGCTGGTGGCCATGAATACAGCGCGATCTAAAATCATTGACTTAGGCGACGAGCTTAGCACTGATCATATGAAGATTTTCAAGAAAACTGGAACACTAAACATAGCAGTGGTGTTACCCGTGAACTCATGCGTGAGCTTAACGGAGGGGCATACGCTCGCTATGTCGTGCTTTTTAACTTCTGTGGCCCTGATGGCTACCCTCTTGAGTGCATTAAAGAGACCTTCTAGCACGTGCTGGTAAAGCTTCATGCACTTTGTCCGGGCTAACTGGACTTTATTGACACTAAGAGGAGATTGTATACTGCTGCCGTGAACATGAGCATGAAATTGGCAGTACACGGAACGTTCTGAAAGAGCTATGGTGCAGACACCTTGCCGGGCTGTCGTTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACATCTTTCA ++ +%&%$%'(7:>=:98<5<,56'6@<=CEC@:../--+('+-/.3+)C)C@<<<3?CRSL4<452'+BD;<=@>;4:=@>DAB@B@?B>:=@A8BACFD>@I34+483/+/$(9?67>770/-&&%%&&&&%(&%046722;32*5DBDA>7)*&%$447?8:75;/45,?JCDD05>=?7,))0B?;4:$233?6))?)+*))=>=D>?7&'@HCKJFC>;>?GK9=@7)-&&.;=93*(37''5;>B@I>?>87//;744221.-3++,''+%()=CEIDD@A1<3;@=+'=FB?::%(90.(1'+&&(%&##$#$$,/./,$/3(,377E:90/061<=;A?@@66(*(-.13666<7%%%%%%## +@SRR11410539.1907056 1907056/1 +CAGTATGCTTCGTTCAGTTACACATTGCTAAGGTTAAGCAGACATTCTAAACGGAATCGACAACACCTTAAGGATCAGTGCCAAGCTCGTCGCCTAAGTCAAATGTTTCGGTCAGCGCCTTAACTGGCCCACCAGCTCCTTTATTACCGTTCATACGAAAGACCTTGCAGTACTGGTATTTCGCCCGCGGACAAAGGACACCGTGTCTCACCACTACGAATAATTGCTGAATGCCTTCGGGTTCTGCTATAAGCTCAACCATAACGCGACCATGGTTGAGTTGAGCATCGAACGTTTGATGAACACATAGGGCTGTTCAAGTTGAGGCAAAACGCCTTTTCAACTACTAAGCCACAAGTGCCATCTTTAAGATGTTGACGTGCCTCTGATAAGACCTCCTCCACGGAGTCTCCAAAGCCACGTACGAGCGTCGCGAACCTGTAAAACAGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCCAATACTGGCAAC ++ +)%)%#*%015;7D=525=<4%0-((*+./..-??>56%+'**-'&(#'4551,/,12*''.)(&)2414117><7/*5A6?@673=>AB@GCGF?9<62<+1-)(&''%++%/+),)''$'$$$*.....**,.0=07:78<8441=B>F96'%$(,-0$%&%)$02)$++$#'$%0'6:49/.-'.2258411)89+$.22-;4026::;:'%%#&'(($#'$'&+)0++%%%&)(0)->87-1*))%$#$&1-:*+30/1000%%&$)+*+$'$%%$&(&76CD)%2,(*06@BC??9@463778.*//17<>=<<')058<6809BCECB;;98:C8<((()'588:')(3B>@7D1*.8<>==9/3.AACG?9?>AEA69;A>G>98C=?=>KCA=A=;71'42/)($#$%$&'' +@SRR11410539.2148301 2148301/1 +GTTGTACTTCGTTCGAGACACGTATTGCTAAGGTTAAACGAAGACGACTACAAGCGAATCGACAGCACCTACAAACTGCCACCATCACAACCAGGCAAGTTAGGTTAGATAGCACTCTAGTGTCAAATCTACAAACAATGGAATTAGCAGGATATCTATCGACATTACAAAATTCAAAATGGCATACACCATCTGTGAATTTGTCAGAATGTGGCATAAGAATAGAATAATTCTTCTATTTTATAAGCTTTGTCACTACAAGGCTGTTGCATCATAGAACTTCCATTCTACATCAGCTTGAGTACACTTAATAGCTAGGGTTACCAATGTCGTGAAGAACTGAAATTTGTCTGCTAATAATGCAGCTTTAACAACCATGTGTTGAACCTTTTTACAAGCCGCATTAATCTTCAGTTCATCACCAATTATAGGATATTCAATAGATCCAGTCAACACGCTTAACAACGTTGCTGTCGATTCCGTTTAGTAGTCGTCTGTTTAACTAACTAACTA ++ +%..8=7;>88886..&/++;:9DE8=98C:;3HJF>>-'$#$%%::?:;A<77.*$%99?@EBI@=>==4<>CB:88420*15B;;;??AE??8=+=44-/.936-.12=6>0+@>:>:@AJBGD@C>:9C<9;0117AB@EFCFKB<C?@=/4+,,,/&1;;(D:;===18'%*$495BA?776580)13967802=7/4''%,06412+399?@://*(--79=?@=>B@@DA=76=?BA:,*02'/57923745'-C-A=ACB?<<>3.2%%%'479>=BA?A)655*/)$))4/27=CEAF<8'',3.($&&%$)))0'./<:@>2+33>@<@>7A=@@??)(&*$%#$('#%+ +@SRR11410539.2352082 2352082/1 +GAATCAGTGTATTTCAGTTCAGTTACGTGTTTGCTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTTTCACTCTTCATTTTTTCAAAAGCGATAAGTTTGTGTAGAGGATTTTATCGAGACAGCTAAAGTGAACGATTTATTGCAGGAACGTTATCTACACAAACTCTTAAGAATGTATAGGGTCCAGCGCAAAAAATGCCAGCTGATAATGGTGCAAGTAGAACTTCGTGCTGATTAAGGTGCTAAACAAACGCTCTTAAAAGTGGATATCTTCTACGCAGCTGTTAACATTTAGGCCGACAACATGAGACAGTGTTAGCAAGATTGTGTCGCAAAACACAACTACCACCACTTTAAGTGGTCCATTAGTAGCTAATATAATCATCAGATTCAGCTTGCATGGCATTGTTAATTATTGTGTTTAAAGTCATATAAACCACCTCCTCCATGTTTGGAATTTATCGATTCCGTTTAGCAGTCGTCTGTTAGTATGTAGTACGTAGCTA ++ +-&&%%$+()%##&)($(&),#)541.+-'&*,011'''%,034041:8,'%',+02550.,79-83*4(,489;9*<''=FB>:5:7DDB'7..)()'$%&#$',3B43+++(&%&&5'(-)*&),$()*'((5:2.&.01237=731'(%&)',5<,/&'+&&?655'3760.62&&;97777359,,6)+(''(*%(,,+1220++<+/13/2*&'''%$%%**&)%'&+$.01,)#%$&&(%(2,,,280+'#*'-)().*+.01:=B?/%.$''%52551.)),12-/(+*<9223019229))(,*&'89?>:7A()6978<3961//2*%&&;)1''3,++0)0+.,0*+***$)13+(/(+$68,-$&&'+-,...+*,.$(*$%$%%#$$(&),+%&%%$&$#$#$%$&'()))+/-*1(0078)#&###$'%,3559=32)56/'''+(4+'/0&%-)&$(,%%%($((,(()'')$ +@SRR11410539.365304 365304/1 +CAAACATTGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGGAGCTAAGTTGTTTAACAAGCGTGTTTAAAGCTTGTGCATTTTGGTTGACCACATCTTGAAGTTTTCCAAATTTTGCCCCACTGTGGAAAGTGAGTCTTGAATTTTGCCAATAGCACTATTAAATTGGTTGGCAATCAATTTTTGGTTCTCATAGAGAACATTCTGTGTGTAACTCCAATACCAGTAGACCTATAAGCCATTTGCATAGCAAATGGTATTTTATGTCACAGCACCTGCACCAAGGTCCAACCAGAAGTGATTGTACCCGCTAACAGTGCAGAAGTGTATTGAGCAATCATTTCATCTGTGAGCAAGGTGGCAAAACAGTAAGGCCGTTAAACTTTTGTGCACAAATGAGGTCTCTAACAGCAATATCACCAAGGCAAGGTTAACTGTCGATTCCGCAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +.%%##$&+'02549;:<5@CB<=?AC9A@AF;<4DECDE<2-//=92+*%%01;726.:;=@E:4@?6>CCF?C=CC@:;9AGBAAF;8;666-ABFBCAF7.08633@CDCC@DC<73/,%+..#&)(&&(%$###$%#%64;9:54'$221/5689<=E@MOHBGEKH=H:=JDHMHF;=ADC>1CB265-63>/0/ARI?&+@A=EA70,++<2'A?<=<13$51/325>A*>@@@>91))')%)89>BABE8@/>AAKDGEEGECBEGA@AA:::;7=5876).9+9>:,=DB@BACC,2<>F?<;/4$$$>FFCDBBB>HGCA?DDC3+-?,-(&,,:F=>==@@;;@>=:8;CEH@868'33;:9;CB'6:2/3'-<3928BB?FCBB>MHBD;%%0A<+ADEBEJKI?55<@56.<*(./.+/>A@A:@9:;,,4;=<:.D+2'&%*-:>CEJC51#&%'>>.>$+--77120.+#& +@SRR11410539.1655558 1655558/1 +GTTTACATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTAGATTACCAGAAGCAGCGTGCATAGCAGGGTCAGCAGCATACACAAGTAATTCCTTAAAACTAAGTCTAAGAGCTATGTAAGTTTACATCCTGATTATGTACAACACCTAGCTCTCTGAAGTGGTATCCAGTTGAAACTACAAATGGAACACCATCAACAAATATTTTCTCACTATTGGTCCAAAAACTTGTAGAGGAGTGGGAACACTGTAGAGAATAAAACATTAAAGTTTGCACAATGCAGAATGCATCTGTCATCAAACAGTTAACACAATTTGGGTGGTATGTCTGATCCCAATATTTAAAATAACGGTCCAAAGAGTTTTAACCTCTCTTCCGTGAAGTCATATTTTAACAAATCCCACTTAATGTAAGGCTTTGTTAAGTCAGTGTCAACAAGGTGCTGTCGATTGATTGTAGTCGTCTGTTTTAACCTTAGCAATACGTAACTTTT ++ +&/0)#$$$#8;>;AI3842@BG@;E>>.B<:;9;AB<6586<:8<>52>@G?@EHDD>:?9>?6A297>5>99IGG@;6<==>A=742-877DC?EG=A576EEEBE28AABEHE;=CD=68>'(>@=@>=;=;9<6MJNEBB78B;:;<@><@CG;CFGEEAECDDF>F@BC=;?@129;((A>=A@C;CAADLDDFH?CE@99==@HCLA>/=53*)%*23&&5??;9<@EG>+/%%))//;5859B@B9:=7974+1D>79BDFIHBAB)'>EJ<<:53303=?BBC?=@.*;@A@DCCE@??C;C?@=?=2423/3=??D=C==<;?CFFF?D=;7=?=B<85>7=))=89%:;A&/;BCB>?:AABEHB>;./;::8;>FD97<>AA>?@<<9;99=GD@D33/+0(,6(/:;<5<8+7A@B@<44,+1,%%+362)($99;@A>@=@7<=:;:9.))**,*023--(*+++ +@SRR11410539.290353 290353/1 +CATTGTACTTCGTTCCAGTTACGTATTGCTAAGTTAAACGGAGCTGACTACAAACGGAATCGACAGCACCTCATCAGGAGATGCCACAACTGCTTATGCTAACTAGTGGAGCAACATTTATTGGCTATTCTGACCAATGTTAATGCACTTTTATCTACTGATAGTAACAAAATTGCCGATAAGTATGTCCTGCAATTTGCACAGACTTTATGAGTGTCTCTATAAAAATAGAGATGTTGACACAGACTTTGTGAATGAGTTTTACGCATATTTGCGTAAACATTTCTCAATGATGATACTCTCTGACGATGCTGTTGTGTGTTTCAATGGCACTTATGCATCTCAAAGGTCTAGTGGCTAGCATAAAGAACTTTAAGTCAGTTCTTTATTATCAAAACAATGTTTTTATGTCTGAAGCAAAATGTTGGACTGAGACTGACCTTACTAAAGGACCTCATGAATTTTGCTCTCAACAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACC ++ +$$)*)+'=AD>=ID%&+8BA<);6BCB>>:+)364146-A<:;;GB@>;;;89=G;=,0+**/1'$$'%&'((05=?70/5+1/*'$%$$($(,18559;4:.45,;ABJD;;3>=-)/75<@HJAH=HFEB9=<=><=;:8,,1$&(***.1'%&&&04=PNJE;((:?60/.74+1%&3;<6&%33><1@5=98A=?;92:@F<;>>@<=33:47ABDG35>DD@A=B=<5%,/.()+00//,,,/,99&8B:A<<:A=?BCAIH52EH4(7;@DEA8:6;75;CC@HIKGFE;54BC=064311B?HGEF??6CB?FHHN<=ICADE?AICDC=@JH>AFJE@>@@6.>D?B==:;?@@HGOK>B<988878A60%89C8BC?=>:>?<>57;,--.-,&&&44?=;64*)%% +@SRR11410539.1559780 1559780/1 +TGTTGTACTTCCGTTCGGTTCAGTATTGCTAGGTTAAACAGACGACTACGAAGCAGATCGACAGCACCTCAGCCCCTATTAAACAGCCTGCGTGTTTGAAAAACATTAGAACCTGTAGAATAAACACGCCAAGTAGGAGTAAGTTGATCTGCGCCAGATAGCAACAGGGACTTCTGTGCAGTTAACACCCCCTGATAAAGAACAGCAACCTGGTTAGAAGTATTTGTTCCTGGTGTTATAACACTGACACCACCAAAAGTATGGTGTAATGTCAAGAATCTCAAGTGTCTGTGGATCACGGACAGCATCAGTAGTGTCAGCAATGTCTCTGCCAAATTGTTGGAAAGGCAGAAGCTTTTTGTTAGACTCAGTAAGAACACCTGTGCCTGTTAAACCATTGAAGTTGAAATTGACACATTTTGTTTTAACCAAATTAGTAGACTTTTAGGTCCACAAACAGTTGCTGGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACA ++ +&*()&,'**-#&/77:%-7/%&.:79<=@6.3BEB?C=.+4,59866%$%-0%+&(3.98@7F1B>???:5BJ;=7?C>@@E/4:4=>FB,;@@?@))*..4A@993$%$,36898570EEJMKEF@A@?,++>;:,'08787A>BA;=8?+4333%3)**/553815C+9)?4CDADH>A=+,1147;4/'+245D;<=:>B;;A7:<<(%%&+,48@BA==<*%<,'0.4:<3>&)0C<76449CD=5722;BI<>AG:763/8<;C:568-<;<:=;=@;<344.266<:64*-32&*3?3378&267==C6689>6>>8+-3569<>8@33:;D@?>B>A@?BA<=?D;B3;B=7,+.DHGJIE:>A@?FJ@BAKD?@FC*+98.(:)8&:7:@D1(8=:0.//5@CB?9:78ICDBB882:=?@=>B@BBDA9A1899>C>;:/-&$ +@SRR11410539.1267913 1267913/1 +GTTGTACTTCGTTCGGTTACGTATTGCTAAGGTTAAAGCAGACGACTACAAACGGAATCGACAGCACCTAGCAAAATGTTGGACTGAGACTGACCTTACTAAGGACCTCATGAATTTTGCTCTCAACCTAATGCTAGTTAAGCTGGGGTGATTGATTATGTGTACCTTCACTTACCCAGATCCATCAAGAATCCTAGGGGCCGGCTGTTTTGTAGATGATATCGTAAAAACAGATGGTACACTTATGATTGAACGGTTCGTGTCTTTAGCTATAGACACCCACTTACTAAACATCCTAATCAGGAGTATGCTGATGTCTTTCATTTCTGTACTTACAATACATAAAGCTACATGATGAGTTAACAGGACACATGTTAGACATGTATTCTATTTATGCTTACTAATGATAACCACTTCAAGGTATTGGGAACCTGAGTTTTATGAGGCTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCCAATACGTAACT ++ +%66(,*(('/4:*9(-12.1*&'2:0'0,--;;;68)*-719@??>80+/052+03=?A?G@E>B?>-@?57DEBH?@FA>@?=.>+=934:6=?C76===?0CB>4B>$$4539:A@9$)6.9.,*'(+,129<;=:1'7.,35237$%22,,4/1/::;B;7ABC7@C3355=2?A:;:47=A@B;EC;=E?=B?CGCCC?:;:6..75>566--996B?DF;5?%%(@B>63+:<,@?@5457CDD:9934:?:;=-$.)*(,88CDCGFC:6601+-CC?<4AB?>@51*;<==4;A>?ID89BBB?D?;;B@C668<43%+..67>>?3?DDAE;=9A?@AA;=GD>?:;AB<757-&'%B9;;>;<>8ECK;:2182,597>;:<>?=<@:5/&4=??>@<;))#$ +@SRR11410539.570916 570916/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTAAACGGAATCGACAGCACCTCTTTTCTCCAAGCAGGGTTACGTGTAAAGGAATTCTCTTACCACGCCTATTTGTGGCCTATTGTTTAGATGAAACATCATGCGTGATAACACCCTTATAAAACATTTTTAAAGCATTGAGCTGATTTGTCTTTATGTGCTTTAAGCTTATTATCATAAACCAAAGCACTCACAGTGTCAACAATTTCAGCAGGACAACGCCGACAAGTTCCGAGGAACATGTCTGGACCTATAGTTTTCATAAGTCTACACACTGAATTGAAATATTCTGGTTCTAGTGTGCCCTTAGTTAGCAATGTGCGTGGTGCAGGTAATTGAGCAGGGTCGCCAATGTACACATAGTGCTTAGCACGTAATCTGGCATTGACAACACTCAAATCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTCTGTTTAACCTTAGCAATACGTAACT ++ +%,,(((9;??>G,>87@A>63''')$),''3;3368:<:?984.)+'-5,),*6=??FCJBEA@@I;JDA;9G,:9;:73=GCC?4=;FADB@&2(<93<&$#(/@A>C@B@CHGCBAEC:;ADC@@CIF;;=9537-+'(69>A=EFK7:;C?:B9:A<=BC@23/,,,78;>=@11;>&&7;<>DE:3682569/500:;CBF?AACEE?@A;8++-2;09+?:;89;B@28=G=6=CE:::A<4D49;H<6=@?BDGFDAB91@>=:>7882<..0+3<=D=>931&&''(*$088::9=:9=D;;>EE?;=7&&5<8992>33+4B=@FHKH:=:ECC98572-&48%9;AGI>-.89836*45611?@<:1') +@SRR11410539.2327545 2327545/1 +CAAGCATGCTTCGTTCAGTTACGTATTGCTAGGTTAAACAGACGACTACAAACAGAATCGACAGCACTAGGACTGGTATGATTTTTGTAGAAAACCCAGATATATTACGCGTATACTTAACAGGTGAAGACGTGTGCACCAAGCACTGTTAAAAACGAGTACAAATTCTGTGATGCCATGCGAAATGCTGTGGTATTGTTGGTGTACTGACATTAGATAATCAGATCTCAATGGTAACTGGTATGATTTCGGTGATTTCATACAAACCACGCCAGGTAGTGAGTTCCCTATTGTAGATTCTTATTATTCATTATTCAATGCCTATATTAACCTTGACCGGGCTTTAACTGCAGAGTCACATGTTGACACTGACTTAACAAAGCCTTACATTAAGTGGGATTTGTTAAAATATGACTTCACGGAAGAGAGGTTAAAACTCTTTGACCGTTATTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTTAACCTTAGCAATACACGTAAC ++ +4+*%&$%$:;@>>N05-=DCD>?<:9=;:->(AKEBC3:;:<==9<8>;236+%*:>3-)&'%%&'''&17B@DFIGFFHEEKQMJ@A5598=EHF;G:@6+2518@CDA?:5)'#$%%$%$%)3420$2/+.+-%0%,+*+-+++2*6<=>@B>6&&9??C;0+BBC<2@A@J?B>0/3:98=B23:=5+-4<8===AB=>9:8>;>GHGAFD66>6471.)()5=2A?FB:;=(-1>?BDDCCA?IDC=@BAAFNC9BAD@CD(@?B:<8-'-(.%%'+%7.*')$%%'(+/.1<@BCCGCFE;<>=?BB?@;8*1%)*:;=9GH@CCA66=<<@@>D>==D4*5('33:<8;,2%/8B?A<>/C@CBHC:8486=JF?C>845?:;=':=BDLFAD>KCLBAI?88<@BCB@::14644588>;>>74+(1/0$$% +@SRR11410539.1057777 1057777/1 +CGTATTACTTCGTTCAGTTGCAGTATTTACTTCAGAGTTAAACAGACGACTACAAAACGGAATCGACAGCACCTAATACAAAGCACAGGTCACGGGGTGTCATGTTTTTCAACTTTGTTATAGAGTGACATATAGTTATTACCGCTATCATAGTAACTTCATATGTCAGATTGATGTGACAATTTAAAGACATTCAACAACATCTTCGGTTCTACATCACAGATCATAAAACCCTTGCCGAGGCTGCTGAAATAAAAGTAGATAAAGACATTGTCAGGACACATTCTTTGCAGGGTTCAGCTTCTCTGCGAAAGTTGCGGCTAGTGTTTTTGGGTTTTCCCATTGGTACGTTAAAGTTGATGAAAACGTATCCAACAATGGCATCAACGTTTTTGACGCTGCTGCGGCCTTCCGCGCCTATCGCCGGCATCGGGGCACAATGCACTGATCAGTAACAGTATAAGGTTGACATAAGCTGACTGTGTGGGGTGCTATCGATTCCGTTGTAGTCGTCTGTTCTTTCTCCTTAATACCTTAACTT ++ +&&(&%(/01367=+4.4+1&&&./314-&,,,*,*$9565923)(:6/,,)$$12.'1$&$&0/42*,((&.-(&&0-044/.(%&&&95400%-3462+7)//27@@2.((&1299,.50+-$21'%/)&+''+$(*'(($)%&76$:#%*(((.134.$&%(,.4,+0*077@8:9,-(+',689-,69224,,,0009*11,.$&+561'$(03.-,')')0*+33.,@C66=(02/'&2877552.9:6>@:/--,(02)+*+,*$%&$**+3;9-%>9;;868)''#%'<;9(,1%%(/2453&$,')'*06;;@33:91*&'&$#%##'#$&$(5.01$$((,243(&$$##$$$$)0%)$%%&%'&'%'$'&'2$'($&1)'=$'''$%%.../+(0*.)+0$03-.)%6>@<+,$2.1/-+250/2412.754-)0%''/3/-,$1,&'*.)+*-1-/*(%)%))*)+-((*')%%##$4643*.*-''"$$ +@SRR11410539.1543409 1543409/1 +CGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAATGAAGACGACTACAAACGGAATCGACAGCACCTACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTAAACAGACTTTAAAATCTGTGTGTCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAACTAATTACTGTCGTTGACAGGACACGAAGCCTTTCGTCTCCTCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAACACATCTAGGTTTTGTCGGGTGTGACCGAAAGGTAAGATGAAACCTTGTCCCTGGTTCAACGAGAAAACATCCAACTCGGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGAGAGCGTCAACATCTAAGATAAAGAGGTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +#&#%%%57:6890;4;5940+0114@AD010@FD::,'1/,107>==<=876201469775;8?F>F=9911))+/>AB,89<>>@B?6%%.'8<<@B@?3;88/,&$/0=BA?=?@=9*C8978;==4>>BBABB?<;/0;?<9::;:;7*+36GF@B?BC1?A=>=D>+':>2+*($%$%')&*/,(,+(+17>@?@?E>:@@<8)++/7:9@IIFC@?@B@GFCFFHAFF=788<2,A*+68<+)?,49ABBPK:5A49A<<@BBGD==@+=>A<=:<,+%%$4547300417/134=44496*243%($&$0)*9-9%+84ECMAE=G>C92G@F=<5=84+;<=>>A@68765>A,/388:;4&+.@:@???;;..+'*),()8447521(''(82'*%&/98C51ECDGD8-(16++,/-6.%%:&2=A<;;,/,09/9<=GC;86$%& +@SRR11410539.854400 854400/1 +GTTGTACTTCAGTTTCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGTCCACACTCTCCCTAGCACCATCATCATGCAGTTCTTGCTGTCGCAGGATTAATAAAAAACACTACAGCTGATGCATACATAACACAGTCTTTTAGCTTAAAACCAGACAAACTAGTATCAACCATATCCAACCATGTCATAATACGCATCACCCAACTAGCAGGCATATAGACCATATTAAAATAAGCTACAGTGGCAAGAGAAGGTAACAAAAACAAACAGAGAAATGCATGCTTATGTTTGACAAACATCATTGCAAAAGCAGACATAGCAATACCCATAGCAAAAAGGTAAGGCATTTTCATACAAAAAAAGAACAAAGACCATTGAGTACTCTGGACTAAAACTAAAGTGAAGTCAAAATTGTGAGTAACAACCAGTGGTGTGTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTATTTAACGCCAGCAATACATGCT ++ +'&''))))+$#'(,,?%,?=:?$496;<=8=87;><:>9=<7;<>88323)*-.6//>1@17B<>/2/164<;20''.7?A9&&.0;9<<88268026))--<<=;(()%%...*.+))$(&)3145?78)&*&+(78;D:7:8;FEM;;3229BD;C>AGBF>KNB>??;<@?B01D@<9<44A?>:/4(*-35937696';2+692:=A76516,5@>ABE?;:;30/E?+89>?>BCA?A7;FBFEEHGAB<<56701=?.-(1.2978+;)*..12893.'%',55,&%(93)))/;6:FF@5-&$*+@=34++;//>B6:,14310-,:=B:>DFIF=<=>;+766574>:<:=>E978958>AB@@JFFCIAB:ABA@E;=FGB>:2C9:K@9<6;?:D=-,2&&)*36@A?4+-,0%&)1+..-,&%8:81720*))+8:47<::C;=BDDGD@=3*53C959ACE>BB<((89<;1+*,/((('.7/=?9:;?=;6148*%-.>>2*,/))%++//03*100'0$#%&&%&+1%7@?<=83).:*.78.&&%)0-..)$%(*(*&&&*(++557756/1/%+4764)*,*+(&-$$%'('%)$'()+&*$,.*0?EGB>A=@79:79E@@?901?:<=?:>=?@6;?=7:1/*$#%#(##$)64:9==:%%21:<=*.(+311115G=2/083;=A5<@>9/,"#%)$%%'$(.12124))%*,+-+.367:>>>9*%<:788<;8I,=5450(-25;7:>65436798<673/65@=+-)*-?23467+$()$)$&&$#%$%#$%&'$***(()&%/2=8*% +@SRR11410539.977310 977310/1 +GTTGTACTTCGTTCGGTTACGTATTGCTAAGGTTAAACAGACGACTACTAAACAGAATCGACAGCACCTACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTAGCTGTCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAACTAATTACTGTCGTTGACAGGACGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGAGGTTTCGTCCGTGTTGCAGCCGATCATCAGCACATCTAGGTTTTGTCCGGGTGTGACCGAAAGGTAAGATGGAGAGCCTTGTCCTATTTCAACGAGAAAACACACGATCAACTCCAGTTTGCCTGTTTTTACAGGTTCGCGACGTGCTCGTACGTGTGGCTTTGGAGACTCCGTGGAGGTCTTATCAGAGGCACGTCAGCATCTTAAAGATGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACATCTTTTT ++ +'''(2):;<>??*3$'(,8>;FEFI8?9HH-DJIINJ?B?B;>:8.,$%128.&)*.6:>=0'(/(7)::ED==BA89?ADGC?G>BG?GF@)>(;<@FDDDG-:4MNBB98;/06EDGD?8<@:55'$/'42.;;>4BCDBDF=@=>78850=FDKCF>G79;@<6==>=@;84,89;CD@01)151,&$)88::?@(%=)69:HFGKFEEEMEIB787+*2(3>BEMC?=?DAEC@B>0'BB@?>9<*%?9@??@CAB@=''@)/C@@CCBA;99,'+<9<=>GJC3<-7=>?BG?66:2./22A333+(:8B@A<@8=G84+?89=9&<2?57LEFFNDHDMHB8C6A;>-)(($'.23277675:=9<@GE:-3C=@?A;5901'.34,5+)23(1*;BF<@@A6D<::942@3=6=;@DA?/4=887EFBEF=0')'%**/:98DE6**(+08=:=+<&7<<>::*+++-4&))+8;95=0=;<..;=665'''9<8*2578:;>B?:=7=@<=<=B0:()))+0)=@A45:42,<,2$%.*8*)))*''//,/66A?@:+AI5<15,-88>:?C@B99'(6;;;@5@B?D@7;DA-$'.98,879=;3./8-',A(01:=A@357<:@0*+''',?95D@1.9678;3@8463-1=<>?;>B?>3.6031164/469-3.)867370'$&/;42+3*+5:.:%&?11?C;8@:9@8AADDKFKIKPFB@//3BB;?B7024841478:5F;1+,:77;):AD@+$/&+==;79%&8A77;:8=@?@E?A>C?>1&++8=;:@AAGHE201(.055?AAE@=<70' +@SRR11410539.1100671 1100671/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTGATTTGAGTGTTGTCAATGCCAGATTACGTGCTAAGCACTATGTACATTGGCGACCCTGCTCAATTACCTGCACCACGCATTGTAACTAAGGGCACACTAGAACCAGAATATTTCAATTCAGTGTGTAGACTTATGAAAACTATAGGTCAGACATGTTCCTCGGAACTTGTCGGCGTTGTCCTGCTGAAATTGTTGACACTGTGTAGTGCTTTTTGGTTTATGATAATAAGCTTAAAGCACATAAAGACAAAATCAGCTCAATGCTTTAAAAATGTTTTATAAGGGTGTTATCACGCATGATGTTCATCTGCAATTAACAGGCCACAAATAGGCGTGGTAAAGAATTCTTACGTAACCCTGCTTGGAAAAGAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +%',,/4656/77B56/?AD@B986)*8EHB=A?@BAC@@:=8:BCEAA47FE@2DFEDDCC3821=*;@47-?<(8>=:>67651/%%1)/;A>B:05>>7D:6@;58787*8AE1/:615;?;*51/0,1-(;@<=>/<8:68A9?C@-%819?DHE78:9,0,1%%+53546>7?@577=?<>@?;./,,44<=C80=:8D8>:==>;=>@GPOHE?BCBFA>50'19??9@<:?A=:<<8:=51/<41.680..34)3674,15667;;=44-.063D-0412%2*033666?C??<=:;-,*4427878920)-0AA=KGHCC<=77>=>;?::CFF@BAGEABBA?D?=:..$$ +@SRR11410539.1398437 1398437/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAAGGTTAAACAGACGACTACAAGCATCGACAGCACCTACAAAGAAAACAGTACACAACAACCATAAAACCAGTTACTTATAAATTGGATGGTGTTGTTTGTACAGAAATTGACCCTAAGTTGGACAATTATTATAAGAAAGACAATTCTTATTTCACAGAGCAACCAATTGATCTTGTACCAAACCAACCATATCCAAACGCAAGCTTCGATAATTTTAAGTTTGTATGTGATAATATCAAATTGCTGATGATTTAAACCAGTTAACTGGTTATAAAAACCTGCTTCAAGAGAGCAAGTTACATTTTCCTGACTTAAATGGTGATGTGGTGGCTATTGATTATAAACACTACACCCTCTTTTAAGAAGGAGAGGTGCTGTCGATTCCGTTTTGTAGTCGTCTGTTTAACATAGCAACCATGGC ++ +$#(+...24537A63,6<8?=<@==A=?9<:&)6G>:;$9=<=?6543*,+,%,/44<<;EF>51128@/0;=C:;C?**@;00$78FE@:9$$74.*+21<=?:613,/--.5?9;:=6%(&/*1,<;;?99;CD4<;<==@::%5DCEF?E::><,1.-?<;=55(,355=A?;86>9:><62%&02?BGBDD1,>368:3))476A@BSIHCG=GJJGKCC?5::<@::=23-4'*(219@4<7(002*223-3+/8;88=NE?>@D;++0:<<86:>BFB?6@?B?C>=325=;@A@GAB@.5*3,8:579?<8D2:?642>9;<4915(;@8997A?A433%%+6(+.0*:;==D?<>7-2;;<@B@@D:9.:>@<=<>1??>&;1/4*-&+*)3::<4;CAA>ABC?@>4<;>.&ECDDHHEDCCFC=864)*(8%-3;=5;,2AA9+:45598A;*/-/2>@5650/(#&&(&''88)30529:;40*00<>?>+8E>?E@CLE=**=B?A@?@3')'2/8B>>>6$$5=@:1+)7=8:88:579/88/)++//,.0=D0:*+%%.0+%$%+**$)))))))*+)56?D.495;864>7<98669<97<=B7>>8834+*'#&%$%),/0/:=>@G+*(%-:04**:?51B;EFGDDFA@?;59=43)//129;5* +@SRR11410539.906274 906274/1 +CGGTATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCAACACCTGTTGAGAGCAAGAATTCATGAGGTCCTTTTAGTAAGGTCAGTCTCAGTCCAACATTTTTGCTTCAGACATAAAAACATTGTTTTTATTAATAAAGAACTGACTTAAGTTCTTTATGCTAGCCACTAGACCTTGAGATGCATAAGTGCTATTGAAACACACAACAGCATCGTCAGAGTATCATCATTGAAATGTTTACGCAAATATGCGTAAAACTCATTCACAAAGTCTCTGTGTCGACATCTCTATTTCTATAGAGACACTCATAAAGTCTGTGTTGTAAATTGCGGACATACTTATCGGCAATTTTGTTACCATCAGTAGATAAAAGTGCATTAACATTGGCCGTGACAGCTTGACAAATGTTAAAACACTATTAGCATAAGCAGTTGTGGCATCTCTAAGGGAGGTTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +2#$%$$$*)(.%%,($2ECCC<4D?@2===DF?:4423>?<<CB>AGFI@C@HE;3-099;AB.:7B;?F@>9DF?DDF?&&33/1435(0<;@8:9998A:BBB9=7:;GB?B@E6D/F<>449B?4'9$8?:>;;5++,8853/;7-)+)'(*7:;01@BAAE<>C?A>=:;9BA84-4)))-3*&-%$'*//9<=?BC;@87,<+0354??2?-9<>;67>>>@EFH@A>>:;?/.46=2B@@;=>=7>18:FA=CMG?>B=@682A4A;ECB58FD;767DFB--0&('%$$31<:97<10)%&&1,*(7&*89C:6A>@G@,/7;@H<=A;6?=;<@A;<500-..3@:=BCAH:,.,1*- +@SRR11410539.225069 225069/1 +CATTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCGGAATCGACAGCACCTAGATTCTTCCTTGCCATGTTGAGTGAGCGGTGAACCAAGACGCAGTATTATTGGGTAAACCTTGGGGCCGACGTTGTTTTGATCGCGCCCCACTGCGTTCTCCATTCTGGTTACTGCCAGTTGAATCTGAGGTCCGCAACGTAATGCGGGGTGCATTTCGCTGATTTTGGGGTCCATTATCAGACATTTTAGTTTGTTCGTTTAGATGGAAATCTAAAAAACAACTTTTACGAACATCATGATACTCTAAAGTCTTCCATAGAACGAACAACACTTTACAAGACTGCAATTTAGGTTCCTGGCAATTAATTGTAAAAGGTAAACAGGAAACTGTATAATTACGATATCGATGTACTGAATGGGTGATTTAGAACCAGCCTCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACC ++ +*'().7155A<=L?3,8BD8<1.>;;@D@/)*,)<6+A?=;;&3#$'(6=@E=@;CE?=2%%&%''26475?>BCGBIF?::>99+4/)/28,+('./.9@;714C@AB69305A:>A9;>9=)2@>;<=B><74515658:76;:8;C-/2;@CEACC6:GE<@9AIE=AJB::;:=4>/0+00:)4%%03689BAA48C7DBD08;=>3.,0)+///%()7666,+-.+?89?@BFGJ;:7CDICAA6<852$%?A><>6<=443210/%%%%%$),,30%10/:><8'%*=+GI05>BI@/562930*48456&&,$$$%'22<>>>?@8@>?@@@@AF=ECTL>A:?B;757949;/.23@66FA;>CCE<:;<=BBHB>54*. +@SRR11410539.1307255 1307255/1 +CAGTGTACTTCGTTCAGTTACGTATTGGAGTTAAACAGACGACTACAAACGGAATCGACAGCACCTACACAGACCATTCAGTAGCAGTGACAATATTGCTTTGCTTGTACAGTAAGTGACAACAGATGTTTCATCTCGTTGACTTTCAGGTTACTATAGCAGAATATTACTAATTATTATGAGGACTTTTAAAGTTTCCATTTGGAATCTTGATTACATCATAAACCTCATAGTAAAAAATTTATCTAAGTCACTAGCTGAGAATAAATATTCTCAATTAGATGAAAGAGCAACCAATGGAGATTGATTAAACGAACATGAAAATTATTCTTTCTTGGCACTGATAACACTCGCTACTTGTGAGCTTTATCACTACCAAGAGTGTTAGAAGGTACAATTGCTTTTAAAGGAACCTTGCTCTTCTGGAACATACGAGGCATTCACCATTTCAAGGTGCTTTTGTCGATTCCGTTGTAGTCGTCTGTTCAACGCCCAGCAATATGGC ++ +-&&'&(&69;::D1,$-<==244<=;=936568;=4:EEGAA<=C?A;8778=?<:94;::;//==966:73),$,*/300/88-;>A>67,1265*6(5>C;<:1177:99898:228=>D@?@6=..3650*+:CD8:9:+2;975&'-$%'%%)5(1''.2-+((%&$56664;:<%'/-8<8A21:69>?<@CF>??A?FG-2%&*8<5)).>A:;=@=>;673<>>BC@;>5190,%&$((-)))&2&2$$#($*)' +@SRR11410539.728888 728888/1 +GTTGTACTTCGTTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAGCAAGTCGACAGCACCTACAAACTGCCACCATCACAACCAGGCCAAGTTAAGGTTAGATAGCACTCTAGTGTCAAATCTACAAACAATGGAATTAGCAGGATATCTATCGACATTGCAATTCCAAAATAGGCATACACCATCTGTGGTTGTCAGGAATGTGTGGCATAAGAATAGAATAATTCTTCTATTTTATAAGCTTTGTCACTACAAGGCTGTGCATCATAGAACTTCCATTCTACATCAGCTTGAGGTACACACTTAATAGCTTTAGGGTTACCAATGTCGTGAAGAAACTGGGAATTTGTCTGCTAATAATGCAGCTTTAACAACCATGTGTTGAACCTTTCTACAAGCCGCATTAATCTTCAGTTCATCACCAATTATGGAATGTTCAAATAGTCCAGTCAACACGCTTAACAAGGTGACGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +'()(,+125032450+8:71''//12-08019>:84489$6&&(,4/,1C>BB@9=B?BB2::6?@CBC8C2;:;>9B34.>A@A@>15(.-,09654C82;>?=@@B88CC@87>:<;@C;=<;77'6>@CB>228:-))'769@:==9;1-)1-%.$%%2=89;9>>@A<;*+(+?B;;==:;,,*,*4>9:;>96(&),365??BB;@A@AABBA<93,.$$$$#)9?=6B<7..374,,>?FE422<@B<*))79:>4,(7/,7087<5757?C@=?F>;<1.(%(()9;<=0*A@DC;((:44HDD>AHEDDBFI;<;;C@68243*463<..3==9=9,,'3;??@>@88@EFD?76$+.,$#67$68;<,(@C@9C:))>=CB),+&'#$##&$&,12>CDFIE=@=HDG:=D>>@;:AB9EDHFH73321/188-@GEB2,$ +@SRR11410539.1791086 1791086/1 +CAATGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACATTTAAGCAGGTGACACCTTCACGCATGATGTTTCATCTGCAATTAACAGGCCACAAATAGGCGTGGTAGAGAATTGCTTACACGTAACCCTGCTTGGAGAAAGCTGTCTTTATTTCACCTTATAATTCACAGAATGCTGTAGCCTCAAAGATTTTGGGACTACCAACTCAAACTGTTGATTCATCACAGGGCTCAGAATATGACTATGTCATATTCACTCAAACCACTGAAACAGCTCACTCTTGTAATGTAAACAGATTTAATGTTGCTATTACCAAGAGCAAAAGTAGGCATACTTTGCATAATGTCTGATAAGACCTTTATGACAAGTTGCAATTCCACAGAATCTTGAAATTCCACGTAGGAATGTGGCAACTTTACAAGCTGAAAATGTAACAGGACTCTTAGGTGCTGTCGATTTCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAACT ++ +.$%)),/569889;/DKHGK?H@8AEFFDEC@CB:2$$*&;9;ABB>D?A==?7:*1('%&#$%$$..9$AC=BA@9=./879988>C*;11=>;55@A>877<=-00/8AGA?AB-,0B73<22>??=C;;9;>EF>)@IIOB;>CB<@CC>99B>ACD>79:12--=??::@:::@@D?92<-+.<=AC;6:@:93@2@D?-B)(0:02'<=:49:7?437-.2515:>GGA??A@F@89::;;6B;=;7-4HN99IG@?:69./(?B6DB0+)**)(*589&&';>A;B;<355B;@=;994;0514>@CAB;?=99;%3$%$$$$+*/(*'22'-989=D=8;$8E?>BFIF56567>>=>>:<:83@KJ>:35528;@5066?BHF>BDCD:57-,883/9:8D7;A82<9;?:==<<991:/01&'))'*2630/++ +@SRR11410539.928929 928929/1 +CGGTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACGAACGACTACAACAGATCGACAGCACCTAGCACATCACTACACCTTTAGATACATTTCTTTATTTAACAAAAAGGTGCACAGCGCAGCTTTCTTTAAAAAGTACTAAAGGAAACACCATTAAAGACTACACGTCTCTTTGGTGAAAGTACTAAAGAACCAATAGAAATGCTTTGTGGAAATACAAATGATATAAGCAATTGTTATCCAGAAAGGTACTAAAGAGTGTGAACATAACCATCCACTGAATATGTGCTAAAAGAAACATCATTAGTAAGTGAAATGTCAAGTACAAGTAAATAACAGAATAGAAGCACCAGGTAAGAATGAGTAAACTGGTGTTAGAAGCAGAATACAGTGAGATGACATAAGGAATAGTAAAGTATTAAAGGCAACTACATGACTGTATTCACCAAGGTGCTGTGATTCTTAGTAATCTGTTGCAACAGCAGCTAATACATGT ++ +4$%%#(&89<68@75*,@1@C=BBBBBBCI?JGIDGFJ@@;66('')8?BG=::?;1-+&''(4346'?@9&&(;;<<=2.<;<:::<9<:(.*',(((A===GR,;=;&:8;:<9@CB228::D1ADGBF?>?C9%%103*,$1?@>F=JH@((=8797464@<89-.('&)?:A==BBA9459<=:;@==@:AGIEB967=73:6@/=>4>A=8@2?90-06>60/025DC?><>@E--4%&&&,-')&*69996<2)>;===24*3+@A/8><=<;=,/,&01585.;987)4=7==6854900+7?<57+).-/0('$$('$$3:2.58)-/.0+((1$$&*)%%(+)&& +@SRR11410539.891112 891112/1 +CAGTATGCGCTACGTTCAGTTACGTATTGCTAAGGTTTAAACAGACGACTACAAACGGAATCGACAGCACCTTAGCGGCCTTCTGTAAAACACACCAGAAATTTTGAGCAGTTTCAAGAGTGCGGGAGAAAATTGATCGTACAACACGAAGGCAGCCTCTGATGCAAATGCATAAAGAGGACTCAGTATTGATTTCTGTTCACCAATATTCCAGGCACCTTTTTTAGCTTTTTCCTTTTTGTAACTTTAAAATTACCACAGGATTCAACAATTTGTTTGAATGCTTTTATAATCCAAACCTTTCACAGTTTCCACAAAGCACTTGTGGAAGCAGAAAAGATAGCAAAATAATGGCGGTCTTCATTGGTTAAAGTCACCAGCAATATTGATGTTGACTTTCTCTTTTTGGAGTATTTCAAGAAGGGTTAATATTAAGACCTTCGGAACCTTCTCCAACAACACCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAGCCTTAGCAATACGTAAC ++ +&#&((%%$%%/&<;G=,08?@A;98611195,.,/+,)037:;45.2(*1=<;7>,9*/8@FC>8==7>=><;>5.57D<@82/?D;93>;=B;63.32<<:58)$9A?/:1=8;8?CDE9:?+,<=6%&2B?=?A>@IEFFA=@?B=A@D?,000DEACBE)/FGF?I@EDEFDB:97ACCLEC7::8DEE<>BDACFE@B@;7667+**0()&19;@F@::?233',*+@<9&&.),>BEHE:?EB7.F&AHHGGEGH=@;;35)3HJCCB:C@@?-*.(072CC93578:?C?>;@6E+,91/*6;51-)..857<@=F@BEC=>?==@CE@FB:73>;79-3CCE>@C@A=BAB?A:>BF@FCJC?8:30)=-&*;=<=KFB;>@A@,.9?ACFBBCC<::8<:4??:?CQKHB>>18-=B@D@D=(/'&%.'&&%$&%#$+,$.(%'&$(%+,&%$%'#'%%($$%&&*%$)/<869990,1<;==9557CDC@@=A=876>//12,-''',7113+%14+-))225>3(%%&%&$($$%%%$$*-'&('*><3253438;70''$(&'$%+))%$"%$ +@SRR11410539.2161861 2161861/1 +TGTTGTACTTCGTTCCGGTTACGTATTGCTAAGGTTAAACAGACGACTACAAAGCAAGATCGACAGCACCTCGGTAACTCTAAGGAGCTGGTGGCCCTTAGTTACGAAGGCGCCGATCTAAGGAAGATCATTTGACTTAGGCGACGAGCTTGGCACTGATCCTTATCAGATTTTCAAGAAAACTGGAACACTAAACATAGCAGGTGGTGTTACCCGTGAACTCATGCGTGAGCTTAACGGAGGGGCATACACTCGCTATGTCGTAACAACTTCTGTGGCTGATGGCTACCCTCTTGAGTGCATTAAAGACCTTTAGCACGTGCTGAGTAGCTTCATGCACTTTGTCCGAACAACTGGACTTTATTGACACTAAGAGGGGTGTATACTGCTGCCGTGAACATGAGCATGAAGTACTTGGTACACGAACGTTCTGAAAAGAGCTATGAATTGCAGACACCTTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATATAA ++ +&)004:4:AC=@D>%,)/4;B?9:66:)<<:;-AB;890=;733)*%$1$%&(29<;9:297>><4&(-'''''$))%.&+6.,*2#&22$$)(+(-)()&$$&$%),5/&=+***'+*(,/9129?C=<=?>D><:9300,,,,$)(''())..9..(%%$$,-.--1)*14.6823?@D??547688>>6BK:-7402;A45=>ADDE>5(())&&0()*+.722&#&,+'#+$%#%&-/59?D<.-.636=ABEG?A?-/*,(<<<:3.2,0*-%((%$%37:982/=678E=..4)'')((5=896/2BEFFGEA?DA>GK82)+;7<=>CC@:;:84<1/*)%%''1?@?GA=8357&-&899C>5?//0:=?HAHCCFB;@;=A:;EF>9-$&#&,$(++.-)%& +@SRR11410539.478078 478078/1 +CGGTATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTCCAGCAGATTCAACGGTACTATTACCGTTGAAAAGCAAAAGCTCCTTGAACAATGGAACCTAGTAATAGGTTTCGCCACATGGATTGTCTTCTACAATTTGCCTATGCCAACAGGAATAGGTTTTTTTGTATATGAATTAAGTTAATTTTCCTTTGGCTGTTATGGCCAGTAACTTTAGCTTGTTTGTGCTTGCTGCTGTTTACAGAATAAATTGGATCACCGGTGGAATTGCTATCGCAATGGCTTACATCTTATGGGCTTGATGTGGCTCCAGCTGCTTCATTTAGCTATCAGCTGTTTGCGCGTACGCGTTCCATGTGGTCATTCAATCCGAAACTAACATTCTTCTCAACGTGCACTCCGTGGCGCTATTCTGACTCAAGGTGCTGTCGATTCCGTTTGTAATCGTCTGTTACAAACATCTGTGCGTAAC ++ ++%-58339:<;799&4IHJLB;??=A?<6C@?DE5ACFED>@=B6G3>C598%3(*+$'03&>&'7,390-+4$',>B@B@>>=%%()CF?5666*4*+9>DB>>:@A>C<<1-:;BC=66CJI(;&%%&4*.(,$49+;=A690**&&%;D<>0EA@?JEBB.(=23>4%%059JFCA<5-9:6,%1%24344@DEFBMQH586:=,2443,-(.6:BA=?G;92365<0@CD?FGD9BE8<87577A24,,,5=CHD:<77335+,,,,***473.'(%''---2065=38=A)<1-'.')5:;4=>4110*%+.21:9<046<=B/,%'6>:8?976)"&#%$%%%&&%$%,%$$%$ +@SRR11410539.1713102 1713102/1 +GTTGTACTTCGTTCAGTTACGTACGCTAAGGTTAAACAGACGACTACAAACAGATCGACAGCACCTTTAGCTTGGTTGTACGCTGCTGTTATAAATGGAGACGGAGTGTGGTTTCTCGAATCGATTTACCACAACTCTTAATGACTTTAACCTTGTGGCTATGAAGTACAATTATGAACCTCTAACACAAGACCATGTTGACATACTAGGACCTCTTTCTGCTCAAACTGGAATTGCCGTTTTAGATATGTGTGCTTCATTAAAAGAATTTACTGCAAATGGTATGAATGGACGTACCATATTGGGTAGTGCTTTATTAGAAGATGAATTTACACCTTTTGATGTTGTTAGACAATGCTCAGGTGTTACTTTCCAAAGTGCAGTGAAAAAGAACAATCAAGGGTACACACACCACTGGTTGTTACTCACAATTTTGACTTCTTTTAGTTTTAGTCAGAGTACTCAATGGTCTTTGTTCAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAGCCCGTAACT ++ +.()$''77:<;H5729@?./-($$%*0##*/44@=<990,.?@83,/=5/1**'3?=?@BD3'66776:BGDC@B4>E,)FIFG?BFJFC:5,;@=$(&,>3'6;A>@69*$572=@@ADF<;74?A=59:FC=A@B?DRRDGI9?LABD@;;).-9=F=<=3JJMA=AA:1&*,8CC=@AA=?=FG5%$'--2<87>8;=?95/1<;>CCCF>BA8566DE;99FG(0==:??;78;3996=.;+<@CCA?FEJB?7;=CDD@?;@?JJ@GD;?>823102/5*-:<-@6'''<<:?IJCAB:D8927+DC-&'@@A=82;')3-.:6+327365<8?D-38C+?4,5486:788:869:CKF;AEL;4:=?F;8.)*5$*%=%$3@DE@6?<=KFLEGD021;=7()1:CDGLJCE/5?B?8723444,(&****',.-%' +@SRR11410539.2261640 2261640/1 +GTTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTGCAAACGGAATCGACAGCACCTAGGACTGGTATGATTTTGTAAGCCGAATATATTACGCGTATACGCCAACTTAGGTGAACGCGTACGCCAAGCTTTGTTAAAACAGTACAATTCTGTGATGCCATGCGAAATGCTGGTATTGTTGGTGTACTGACATTAGATAATCAAGATGTCAATGGTAACTGGTATGATTTCGGTGATTTCATACAAGCAAACCACGCCAGGTAATTAGGTTCCTGTTGTAGATTCTTATTATTCGTGTGTGCCTATATTAACCTTGACCAGGGCTTTAACTGCAGAGTCACATGTTGACACTGACTTAACAAAGCCTTACATTAAGTGGGATTTGTTAAAATATGACTTCACGGAAGAGTTAAAACTCTTTGACCGTTATTAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTATGCCAGCATCTATCAAACTT ++ +%%&(5619MGIK''+&%&74'688@9?@DB<=DHJ8<38=:FAB;?<21,779=DE<;:8<:;A55=6CJ;CFE?GF=@;=C>@:;BD=/%#':CFB67>AD?@():CAA<:@9<9=>@?DF.>,BBB=?*9*.1%2A>@A=><5=*+**%%><>;=J?DA><6;;GB=C@89<5?B1'8$*$$$347;777;=>BA@:;2672CCCELMBEB;=>>=@87FDCF=8EFD-/1>?ADEJBB**939IKFA;7*?@DA>98&&6678578=6==09=@AKG<@ANIK2B>>9@;9@7999*&###$$##&)*%&%%$%#&'' +@SRR11410539.1154669 1154669/1 +TGTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACTACAAACGGAATCGACAGCACCTCACAACTTGCGTGTGGAGGTTAATGTTGTCTACTGTTGTAAACACCTTAATAGTCCTCCTTCTCTCAAAAGAAAGAAGTGTCTTAAGGTGTCAAAGGTGATAACTTCACCATCTAGGTGGAATGTGGTAGGATTACTAGTGTAATATACACTTTTTTATCACCTCTCTTAAGAAAATTCTATACCTAGTTGTGTGGGTGTCAGAATAGGACCAATCTTTATAGGAACCAACAAGTGAGATGGTTTCAATAAAAAAATGTTCTTCAGGTGTTTTAGAAGAAGAAGTAAGATAACCATTATACGCTGTAACAGCATCAGGTGAGAAGAAACAGAAACTGTAGCTGGCACTTTGAGATCTCTACCGAAGGCAGCTTCTTCCAAATTAGGTGCTGTCGATTCCGTTGAGTCGTCTGTTTAACCTTAACAACTCGC ++ +%&$%)41..269G;:56>?-C=;772+&&%')/7=>A;.1+3<<;>74105:9/(4555;=>=<=?CB>A?FKHG@A89GE=<@=:46&=B?:=@E>7%)%9<<:869:<<'/'880(5)'>45)(?BA@B10/8@B@>=C>B;94=:=??9./;6;AD9>9FH<.4<:A=9AD@;98:;79;>4/15594577%>BFA>>+4;<>=B?==89@>9.=58'8.1,--F-(2E@CF1D.;D99BB;=:8/.*9*3788;**:6FJLG9=944@BEADA@;=>B>C?FAB:7?@??AG:78441895&07,8:;?88>A;857<<98<9<>>9;=84**08:;6,%*)'&&$)+&'$&656A/6NLHKHCB@>?BLB?A@BMD7:9A>>7=697;===77%227745&&*$)"#&$# +@SRR11410539.1763932 1763932/1 +GTTGTACTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACAGAATCGACAGCACCTACTTTTGAAGAAGCTGCGCTGTACTCTTTTTGTTAAATAAAGAAATGTATCTAAAGTTGCGTAGTGATGTGCTATTACCTCTTACGCAATATAATGAATCTTAGCTCTTTATAATAAGTACAAGTATTTAGTGGAGCAATGGATTCTGACTAGCTACAGAAGCTGCTTGTTGTCATCTCGCAAGGCTCTCAATGACTTCAGTAACTCGGGTTCCTGTGATGTTTCTTTGCAACCACCACAAACCTCTATCACCCTCAGCTGTTTTGCAGAGTGGTTTTAGAAAATGGCGATTTCCCATCTGGTAAAGTTGGGGGTTGTATATGGTACAGAGTAACTTTGGTACAACTACACTTAACGGTCTTTGGCTTGATGACGTAGTTTACTGTCAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTCAACCTTAGCAATGCGTGA ++ +058341:;748A(-&6=<4;:<<%)6:<0122>-3,//8;;?IO>55D6<:4>B38@AG@7&%-%$:HGB7CG?CC;23/812?21%)=A@3;-.GNCB<:9?ED?@>D=DC?@A@88=;A@<=8???AHD==7&&-&##';?EE@@A:32'(-***3,-%&*24767:5;GHC@C=<689.%'$%%(,4,**-')((*+-1:5000,47B;<97:<<%%77(2:24/@:;<>B66)1'*,8;=-6(+=@:%'%%,27>%CDA9=<6(;5544=;<386;<@>B>?31(23:86877>;ADCR>;3:,)0@?C:@H42-2);?A448&%:<,9;A>=BD+0:00$*4.$&5>AB@64/(%%+07/.7,-9>:4$$'..563<&&59..%%'(<D=((;44161/9FFE<>C:2A=>*=:75:(%1=335**(7;9..*,8;8597&&&'./1500,()(*''(')$$ +@SRR11410539.123001 123001/1 +CGTATTACTTCGTTCCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGAATCGACAGCACCTGGAATTTGGTGCCACTTCTGCTGCTCTTCAACCTGAAGAAGAGCAAGAAAGAAGCGATTGGTTAGATGATGATAGTCAACAAACTGTTGGTCAACAAGACGGCAGTGAGGACAATCAGACAACTACTATTCAAACAATTGTTGAGGTTCAACCTCAATTAGAGATGCTACCAGTTGTTCAGACTATTAAGTGAATAGTTTTAGTGAAGTTTATTTAAAACTTACTGACAATGTATACATTAAAATGCAGACATTGTGGAAGAAGCTAAAAGGTAAAACCAACAGTGGTTGTTAATGCAGCCAATGTTTACCTTAAACATGGAGGAGGTGTTGCAGGAGCCTTAAATAAGGCTACTAACAATGCCATGCAAGTTGAATCTGATGAAGGTGCTGTCGATTCCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +)('%#%,3577:@>*+/<>2?<<=>@DIBB=@:579?>?@>;;(589=;86./=BEIE@,,@>GFDDADF6@<6++45.&$%%$$%$'-36GC45:=:;B>?FHD9@44C=A6<>CHB30(,((4@AE>>).9:6DEFBGJCC@7:,,,+8::>:=@>>CCDF6ADIGL66541,--'-(><::98>@>G800,6'&4,244=@AAEGG@EEC>?D@523..,/CCDH>@HG6=<-13571ACA>9=@F?2++-,,791:AD?@A4+119<:ILDGCDD8@<+7>?C<:BD>DA=54/(+55512B@A89>:5749;71(?-894((=,@E@?I>7ADAG2CCC=A8@D@@>;A<<4737<.0:;9F:3,73621-<;:;;;=<=(=CBJH76..839;951145.$+$%&59:261-685@@CD1B(&B?B<@@CD?4:CA91,2271:6244=47NC>@:)1(-+.-847:5?CD2774,,2.66-;''796@AF->2/3+,(%#*$#%*-2799:2*&#$$##'$#$45.'8D:=AD>;;(<4?DBC;<,,%%0:;<9:&)(?:766>>@99AD?D??AFGB56A@A@>?;#&#'(0:<999?>66;@=-+@>@FF9935+,0++06<;88<2,,/99.,-148$$5:99923;<84,-5-5%'1?<;++5/026714+,/3678@@==?&&BA?DED=67'''()-/)*)*(0>::9-=:>AB@5,+**79>DBC7:D8=67;@:<98<==BBCBEC39)2=;=>=6;>43,053.;>86674'*($',',,9;BB>?=990/*$ +@SRR11410539.1671369 1671369/1 +CGTACTTCACCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTGCTGGCTTTAGCTTGTGGGTTTACAAACAATTTGATACTTATAACCTCTGGGCTGCACACAAGACTTTAGAGTTTAGAAAATGTGGCTAATGTTGTAAATAGGGACACTTTGATGGACAACAGGGTGAAGTACCCAGTTTCTATCATTAATAACACTGTTTACACAAAAAAGTTGATGGTGTTGATGTAGAATTGTTTGAAAATAAAACAACATTACCTGTTAATGTAGCATTTCGAGCTTTGGGCTAAGCGCAACATTAAACCAGTACCAGAGGTGAAAATACTCAATAATTTGGGTGTGGACATTGCTGCTAATACTGTGATCTGGACTACAAAGAATGCTCCAGCACATATATCTACTATTGGTGTTTGTTCTATGACTGACAAGGTGCTGTCGGTCGTTTGTAGTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +'')(%%'%%,,'663*&&1168369664GGA@D-74634632%$*0244365<91@@AA?FC<;D859+*%#&&.%$$&'1-/:<<<@?==+=AC=B631987::1<3>@=57..2:>=>8975664398701+&.1,,,('2'+>A@=8:9::988'(08898A95*%33DB500/4?=?A@;=9?>=ABHA2>0I?:>@@3:--=88=50/3:<8//11-069--+&$.+,2222.063767,57:8770*.680A@5863>7>2'''1;<6BC=>34&...299<>;175565;:8?>9<947436?>CA+54C;?@D274.44899/7575710+-)*$%5428<>:4:-1>C?:9>40*,(<@79:<79('$((+,=9>A?;=;:;48DEE11;@D=C54558=151('& +@SRR11410539.219482 219482/1 +CGTATGCTACGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACAGCACCTTCATCGGATTCAACTTGCATGGCATTGTTAGTAGCCTTATTTAGGCTCCTGCAACGCCTCCTCCATGTTTAAGGTAAACATTGGCTGCATTAACAACCACTGTTGGTTTTACCTTTTAGCTTCTTCCATAATGTCTGCATTTTTAATGTATACATTGTCAGTAAGTTTTTAAATAACCACTAAAACTATTCACTTCAATAGTCTGAATAACTGGTAGTTCCATCTCTAATTGAGGTTGAACCTCAACAATTATTGAATAGTAGTTGCATCTGATTGTCCTCTGCCGTCTTGTTGACCAACAGTTTGTTGACTATCATCATCTAACCAATCTTCTTCTTGCTCTTCTTCAGGTTGAGCGAAGTGGCACAATTAGGTGCTGTCGGTCCGTTTGTAGTCGTCCTGTTTAACCTTGGCAATACGTAAC ++ +$(&'$$','14=/5.5AAAA@90>D>??EI'?@ABF0998>.EF?@@?476;),(<::62/,//('&.50.&=(-,@CE2*$)))&'(7;>>BB3B@9?@B@?><:6=<*((+./3:93753-*'&+%.+)+<11GD?371=DGJAA224=AFGFGDDBB?@88@B:?816GFE65=?EEC7<4<=7222#%$&')01:?TF?447423337:EG4.><=:6-*ACULFCEFD<=<8/'1AEA@?ED==AB?D7C?@682;;632.$(('.$'$#(&-%)*394C3?A>?=)/>+,87<--111.>FED19<9963;B@A?AGCBJFDMH=AFD@9BK3<4@@A=0/+-$$+'+''$%*%'#&)(2:1<3//=,,.-7587<>C@6:60'--3@DE93>04;::7&..11%**'&&$$$)3;<9*&'%&#%$-9589;;26@;4:?>:6440+-%)(($&+('134@;;<3*/&&37<542&&47BBIA<601'057?@@@=@-();;@?;;4-3?;;ACD>?>>=A253&()9&8214')''-)3++-,+/0)0*.98ABCA(;00.8:>8:9;8A@BA;1.'121-*./1+0(-5,,66/--%)%'%%%,+$%.%%$$% +@SRR11410539.1565287 1565287/1 +CGGTATGCTTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACTACAAACGGAATCGACACTTCCTTCCCATCTGGTAAAGTTGAGGTTTGTATGGTACAAGTAACTTGTGGTACAACTACGCTTAACGGTCTTTGGCTTGATGACGTAGTTTACTGTCAAGACATGTGATCTGCACCTCTGAAGACATGCTTAACCCTAATTATGAAGATTTACTCATTCGTAAGTCTAATCATAATTTCTTGGTACAGGCTGGTAATGTTCAACTCCAGGGTTATTGGACATTCTATGCAAAATTGTGTACTTAAGCTTAAAGGTTGATACAGCCAATCCTAAGACACCTAAGTATAAGTTTGTTCGCATTCAACCTTAGGACAGACTTTTTCAGTGTTAACTTGTTACAATGGTTCACCATCTGGTGTTTACCAATGTGCTATGAGGCCCAATTTCACTAGGTGCTGTCGGTCCGTTTTGACGGCTCGTCTGTTTAACCTTAGCAATACGTAAC ++ +9+0,*,+/03/@N1<79BCBB@@@:;;@B9:3E@CDG:>88C@FFCD9+EE9>9?75+(###))17>@B?>B@@E@AF5<<;=0%),2@58?@?CCB@@>8?8879;842.)*0+*(/(.#%'*11B7;676>?22$$2>>@AD38365A>7*./+'=78=F?B8(657::83+*99626;<9@E?C:;//3<=KFEC:<28+8110=AGJ8/>C?;A?A::;<69;:>:3@.@>A>?DHD@./;:$/6BCBKE==A67//09=A@86:9::165;+:+;:999>=5555BD$/D:94.''%''-07<89<@45295)/+>>?A@CDF><16-18>;9++$%$%43>F<9;7=AAHE5<+/97&1&'#$+*/51@EFC@CH=E==<=@C<(+@D>=983989--A654.--@ACAB?7<@A@?@6@=>:=007632.0.++'$#$'-4:=@>;::><>59589<@CCBD?:5-,% +@SRR11410539.1083900 1083900/1 +GTTATTCGTTCAGTTACGTATTGCTAAGGTTAAACAGACGACCCCCTATAACAGATCGACAGCACCTCGTGAAATTGGGCCTCATAGCACGTGTATTAAACACCAGATGGTGAACCATTGTAACAAGCTAACTAGAAAATCTGTCCTGGTTGATTACGAACAAACTTATACTTGGAATTTGTGTTAGGTTGGCTGTATCAACCTTAAGCTTAAGTACAATTTTGCATAGAATGTCCAATAACCCTGAGTTGAACATTACCAGCCTGTACCAAGAAATTATGATTAGACTTACGAATGAGTAAATCTTCATAATTAGGGTTAAGCATGTCTTCAGAGTGCAGATCACATGTCTTGGACAGTAGCTTCCTGATGTCATCAAGCCAAAGACCGTTGGTGTAGTTTGTACCACAAGTTACTTGTACCATACAACCCTCAACTTTACCAGATGGGAAGGTGCAATGATTCGTTTGTAGTCGTCTGTTTAACTTATACTTAATACATATT ++ +(%&##%*/;1+')/3279::;>62<89/@=;12,)%)$/'&(%%%#&%%''+),79::B3/57531$&&110,++)-15889?735)/0+$(%$&#%&(/8.,-2/:9682:/@4:=DDAGEA=22((/+*%%&#&&&%7989++.2,.9.*%%%$%%%)2./)%%%/))&'(&)#$$%&&&#.+)'6+/49/.,52/;896:9:7985585768-BCEAGOJ>@<=>=:@5567?&'#//5:B8;1?3@?==>====?;HDE2-7:2.+35767(899KB=??;TI<==;:<@=?IB7BAFGGFFECC=:/0*';72-*(')$$%*)%,443/4-2'$+78A>?@>+&$(+%$$%%)&)''&*51+<::7D@FG9,;;96<6#'+,+)8.5=(%%786>>>::0)278<52??..8;321'#(5269:<405<>9A<27<4;+0+%&&&&%%*.%%$4<94063-,0)@;;<=''&,-(%%$$$))%#$%#$%' diff -r 000000000000 -r 7a82006f7c05 test-data/SRR11410539_seqtk_sample_500_1.fastq.consensus.fasta --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/SRR11410539_seqtk_sample_500_1.fastq.consensus.fasta Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,500 @@ +>SRR11410539_seqtk_sample_500_1.fastq/ARTIC/medaka MN908947.3 +ANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNCCTTACTAAAGGACCTCATGAATTTTGCTCTCAACATACAATGCTAGTT +AAACAGGGTGATGATTATGTGTACCTTCCTTACCCAGATCCATCAAGAATCCTAGGGGCC +GGCTGTTTTGTAGATGATATCGTAAAAACAGATGGTACACTTATGATTGAACGGTTCGTG +TCTTTAGCTATAGATGCTTACCCACTTACTAAACATCCTAATCAGGAGTATGCTGATGTC +TTTCATTTGTACTTACAATACATAAGAAAGCTACATGATGAGTTAACAGGACACATGTTA +GACATGTATTCTGTTATGCTTACTAATGATAACACTTCAAGGTATTGNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNN diff -r 000000000000 -r 7a82006f7c05 test-data/all_fasta.loc --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/all_fasta.loc Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,7 @@ +# Tab separated with three columns: +# - value (Galaxy records this in the Galaxy DB) +# - dbkey (Database key) +# - name (Galaxy shows this in the UI) +# - path (the reference file) +# +test_entry test "Test Reference" ${__HERE__}/nCoV-2019.reference.fasta diff -r 000000000000 -r 7a82006f7c05 test-data/gupplyplex_output.fastq --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/gupplyplex_output.fastq Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,32 @@ +@9bd6c9e7-e630-471b-88f5-f0f46e5b3767 +CATCGGTGTTGGCCCGTTTCAGTTACGTAACCTACCAACCAGCTTTCGATCTCTTGTAGATCTATTCTCTAAACGAACTTTAAAATCTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAACTAGTACTGTCGTCTGACAGGACGAAATAACTCGTCTATCTTCTGCAGGCTGTTACGGTTTTCGTCCGTGTACGGCCGATCATCAACACATCTAGGTTTGTCCGGGTGTGACGAAAATGAATGGAAGCCTTGTCCCCTGGTTTCAACGAGAAAACACGTCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCATGCGTGGCTTTGGAACTCCGTGGAGGTCTTATCAGGGCATCAGCATGTAAAGATGAGCAATACGTAACT ++ +'%*+%%&#$%%%((*,88):*-++*,'$$#$%$#++13/*(%$$&/7%'13)034)--2/,7'$798<@8:>A2/0//1124664;67:>6014*8315---&'%%%%%%.+$%%)*%'''(*.%''37A8I<87*.,/552)$&%%$&=AB>9200402)&%'&)454?;>--8+'),)/8B/0C:=HB1((>&+030DE,6'01**))'+&&'''.0,020//4.&0(*7?A0/.023(2.42-+.(%=1.;:A3'A:)976;.LLP*%(,%2@=61.0&,,4/?D=&&&)(...$$,7)-,'<FD=84:3(2(5/>BB0)B)(4?;*-781/-&'$###*+3++)1>B(&&))&,,-.-(00&2?=;>HE@C:/1.&(9E@70%%--%%%%&%./8;:993&.')4544)%(')*8?B?@F=898&//;1$.98:1..,*==><6B87:8<:<++)+,,))%,,,+%$##&832::>1@ED.1>?@>EC3'%%$&1.-)&&',+,---**:2+(0+,%&#'()*-',002>=A/0<:>2%%-)*22269?C??.<=<>>A<55+&'' +@80de96c0-f65f-45b6-9962-0646f207ffb2 +GATCACTTCGTTCCGGTTACGTAACACTACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTCTAAGCAGACTTTAAAATCGCAACATCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAATAATTACTGTCGTTGACGGACTGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAACACATCTAGGTTTTGTCGGGTGGCAATGAAAGGTAGATGGAGAGCCTTGTCCCTGGTTTCAACGAGAAAACACGTCAACTCAGTTTGCCTGTTTACGGTTCGCGACGTACTCGTAAATGCGGTAACTGGGAACTCGTGGAGGGTCTTATCAGAGGCACGTCAACATCTCTAAAGATGAGCAATACGTAATGCTTGA ++ +$#'%#$/05>=??=:BA;IA2---'$6''()''-&)%-.%&%%1/776AA:4.2$"$%%%-:,.1:@@A>=9900&&*09=50/6:<8>744;>;7863510/3+068481;>?AE8GG=7'&,..(),378899@?;=859ACCB;7334=>9,#%,@@=?TQMFD@CD==:G:=88<=;221?4/<9)&.(:79&%0;:;'=6GA3DGC@<:8((+,-&%'(+8)*)*-''((153+-,+.,)(./588''&7;=:>>=3//+%$"##$# +@197e8890-1cb3-4c52-a783-5ef3ce80953a +CTGCTTCGTTCAGTTACGTATTGCACAAACCAATAACTTTTTCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTGGCTGTCACTCGACTGCATGCTTAGTGCACTCACGCGGTATAATTAATAACTAATTACTGTCGTTGACAGGACACGGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAACATCTAGGTTTGTCAGGTGTGACCGAAAGGTAAAGATAGAGCCTTGTCCCTGGTTTCAACGAGAAAACACACGATCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGATATCATTACGTGGCATTGGAGACTCCGTGGAGGAGGTCTTATCAGAGGCGTCAACATCTTAAAGATGGTAATACGTAACTTG ++ +#$$""&+0.?<<;9'%$$##&$$555:2''+99=?9636@A=E586?;<=CFJA@8''*CD?A?<<:68@5:?F526AAHFAC-;ACEHDCA9=B@@EDA>A<=AB=@664/68:363/8,,267339DI@:CA8?9EA>;)$$$4*45237>B@-?79BEFCG<5892%*+)$%'$%4$%::7;;@/?AE;@CDF@EFH=;;<3><69769444)*((,''+253>63119<=<;8??BJG@C@>4%%-9><=G:=77),$%1'*7:<5640)++58463..',-+(.53341##$$ +@74fdf93b-4411-4aba-8346-7c443da2eead +GTTGTACTTCGTTCAGTTACGTGACAACACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTTAAAATCTGTCGTGCAGCTGTCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAATAATTACTGTCGTTGACAGGACTGAGTAACTCGTCTATCTTCTGCAAGGCATACGGTTTTCGTCCGTGTTGGCAATCCATCATCGGTTTTTTGTCGGGTGTGACCGAAAGGTAGATGGAGAGCCTTGTCCCTACTGGTTTCTTGAAAACACACGTCACTCGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTATTGGCTTTGGAGGCTGTGGAGGATATATCAGAGGCGTCAACATCTTAAAGATGAGCAATACGTAGCCT ++ +#,-.00//9CDH?<16)*%%&#&#&#$#%(''-4457227??:;=7>;63;:::0,1,.02:;84A>5889>>@<1&(()57355>BA7>/&&>=BA;>.>;/,&&:6/+)+(%/1/3470'9-C?C>;*('&&&'&&#&&*%'&,/.*-))*%'%(,%$*%)##''(%$*0%(,139:<0)405C>?BD@BA995,1.((+23311,08,-+/2435/&&%('*%&,&$$&--/,,''$'+).%$'&'(7C/;:;:CBA+%&*/9CE>4801')+**./**%%'1399<635/-$$&%-//&&*%$$''2738018*->A<.:;:75534334556979589:3-*%#$# +@8fbace70-be6b-4be2-b03c-9265c1693576 +ATATCGCCGTTCAGTTACGTGTACACACCAACCAGCACCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTCCCAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCCTCACGCGGTATAATTAATAATAATTACTGTCGTTGACAGGACACGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCGGCCGATCATCAACACACATCTAGGTTTTGTCCGGGTGCTGACCCAGGTAAGATGGAAGCCTTGTCCCACCTAGTTTCAACGAGAAAACACACGTCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTGGAGACTCCAGTGGAGGTCTTATCAGGAGGCACGTCAACATCACTAAAGATGAGCAATACATGTG ++ +##$%%&'*-/,<()13+00'&*'%$$$'(),562%%%%,00660,$**)../0;,.>?ACB3576///2))+&'&'+-+@,015(),@;5;<@@<94/&&&(*+*9==73;5*00'3&96@1.0;BLSN>%%@'(5;9$@JCBB&&'=@DDDJDD=;(.568895562-13*%:>EB:;<55467,2-&%##&*493.<;?-:7B;2>?=9><7*%%$9:@35657232;5>B@05187***',(-4:669:5')458.-??EGD467(+'(&-++-.7?:,::93%#0/0,04+++6=>999(%%$%# +@2c03f5fc-9a7b-479a-8d6c-a5bb76a79ed2 +AGTGTGCTTCGTTCAGTTACGTATTGCTACCAACCAATAAACTTTCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTTGATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACTCACATGGTAGTATAATTAATAACTAGTACTGTCGTTGACAGGACACGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAGCTTTATCTAGGTTTTGTCCGGGTGTGACCGAAGGTAAGATGGAGAGCCTTGTCCCTGTTTTCAACGAGAAAACACGTCAACTCAGTTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGAGCACGTCAACATCTTAAAGATAGGCAATACGTAACTGA ++ +)&%&+,6==>:I7D+@/(9;;18812;0,.-(@HH?BEB?@DBC?0(((=;B?>?AA@BFPI>A53347<;1))9<@?DACF:5;.-((+061B7DB&&?9>D?CFGJADFDF=EEOG;<7787?7B=>:?>=>AC:4>761..86/<.9;;:-9:@C>$6,23<4AEFGG@?F>@>FEC>C@IF)+079>@?A1+:0,',***78@B1::53(+<<<7*$$$;=CDBA=000,)*$$ +@78cf30ba-8f84-45cd-b9b6-0bc6f3500787 +AAACGTACTTCGTTCAGTTACGTATTGCTAACCAACCAACTTTCGATCTGTAGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACTCCGCAGTATAATTAATAACTAATTACTGTCGTTGACAGGACACGAGTAATATTATCTTCTTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAGCACATCTAGGTTTGTGATTGTGACCGAAGGTAAGATGGAGAGCCTTGTCCCTAGTTTCAACGAGAAAACACACGTCAACTCAGTTTGCCTCTTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGAGGCACGTCAACATCTTAAAGATGAGCAATACGTAACTGA ++ +(($%%$#$*/39A9C4:=:''$''&'27,53-/%((,-,$$-3732/12$*120*((6@BFFB*MIE1113667+6;@@;;;-$,6077831;13;7)'%+*,-5&#&--:1+/**9;/*435BDDFA=>@@AG;4:>83:>>C@<--8<8%,4496?866>;;A@:<9:<5/<<$8@(;4>1/.8,>,$%$%)+-=>?C??C>8DF=>?=:226&%$*0026<3476,718:66/,*.&5>;A=<1:38-&''+&'*==89878CFE7//3-4*56>?9*5598..0101(%(*.;9;9410.0*%$2AB:;:CC@>ABFF?D<;;8001ACC5665.))($$## diff -r 000000000000 -r 7a82006f7c05 test-data/nCoV-2019.V1.bed --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/nCoV-2019.V1.bed Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,196 @@ +MN908947.3 30 54 nCoV-2019_1_LEFT 60 + +MN908947.3 385 410 nCoV-2019_1_RIGHT 60 - +MN908947.3 320 342 nCoV-2019_2_LEFT 60 + +MN908947.3 704 726 nCoV-2019_2_RIGHT 60 - +MN908947.3 642 664 nCoV-2019_3_LEFT 60 + +MN908947.3 1004 1028 nCoV-2019_3_RIGHT 60 - +MN908947.3 943 965 nCoV-2019_4_LEFT 60 + +MN908947.3 1312 1337 nCoV-2019_4_RIGHT 60 - +MN908947.3 1242 1264 nCoV-2019_5_LEFT 60 + +MN908947.3 1623 1651 nCoV-2019_5_RIGHT 60 - +MN908947.3 1573 1595 nCoV-2019_6_LEFT 60 + +MN908947.3 1942 1964 nCoV-2019_6_RIGHT 60 - +MN908947.3 1875 1897 nCoV-2019_7_LEFT 60 + +MN908947.3 2247 2269 nCoV-2019_7_RIGHT 60 - +MN908947.3 2181 2205 nCoV-2019_8_LEFT 60 + +MN908947.3 2568 2592 nCoV-2019_8_RIGHT 60 - +MN908947.3 2505 2529 nCoV-2019_9_LEFT 60 + +MN908947.3 2882 2904 nCoV-2019_9_RIGHT 60 - +MN908947.3 2826 2850 nCoV-2019_10_LEFT 60 + +MN908947.3 3183 3210 nCoV-2019_10_RIGHT 60 - +MN908947.3 3144 3166 nCoV-2019_11_LEFT 60 + +MN908947.3 3507 3531 nCoV-2019_11_RIGHT 60 - +MN908947.3 3460 3482 nCoV-2019_12_LEFT 60 + +MN908947.3 3826 3853 nCoV-2019_12_RIGHT 60 - +MN908947.3 3771 3795 nCoV-2019_13_LEFT 60 + +MN908947.3 4142 4164 nCoV-2019_13_RIGHT 60 - +MN908947.3 4054 4077 nCoV-2019_14_LEFT 60 + +MN908947.3 4428 4450 nCoV-2019_14_RIGHT 60 - +MN908947.3 4294 4321 nCoV-2019_15_LEFT 60 + +MN908947.3 4674 4696 nCoV-2019_15_RIGHT 60 - +MN908947.3 4636 4658 nCoV-2019_16_LEFT 60 + +MN908947.3 4995 5017 nCoV-2019_16_RIGHT 60 - +MN908947.3 4939 4966 nCoV-2019_17_LEFT 60 + +MN908947.3 5296 5321 nCoV-2019_17_RIGHT 60 - +MN908947.3 5230 5259 nCoV-2019_18_LEFT 60 + +MN908947.3 5620 5644 nCoV-2019_18_RIGHT 60 - +MN908947.3 5563 5586 nCoV-2019_19_LEFT 60 + +MN908947.3 5932 5957 nCoV-2019_19_RIGHT 60 - +MN908947.3 5867 5894 nCoV-2019_20_LEFT 60 + +MN908947.3 6247 6272 nCoV-2019_20_RIGHT 60 - +MN908947.3 6167 6196 nCoV-2019_21_LEFT 60 + +MN908947.3 6528 6550 nCoV-2019_21_RIGHT 60 - +MN908947.3 6466 6495 nCoV-2019_22_LEFT 60 + +MN908947.3 6846 6873 nCoV-2019_22_RIGHT 60 - +MN908947.3 6718 6745 nCoV-2019_23_LEFT 60 + +MN908947.3 7092 7117 nCoV-2019_23_RIGHT 60 - +MN908947.3 7035 7058 nCoV-2019_24_LEFT 60 + +MN908947.3 7389 7415 nCoV-2019_24_RIGHT 60 - +MN908947.3 7305 7332 nCoV-2019_25_LEFT 60 + +MN908947.3 7671 7694 nCoV-2019_25_RIGHT 60 - +MN908947.3 7626 7651 nCoV-2019_26_LEFT 60 + +MN908947.3 7997 8019 nCoV-2019_26_RIGHT 60 - +MN908947.3 7943 7968 nCoV-2019_27_LEFT 60 + +MN908947.3 8319 8341 nCoV-2019_27_RIGHT 60 - +MN908947.3 8249 8275 nCoV-2019_28_LEFT 60 + +MN908947.3 8635 8661 nCoV-2019_28_RIGHT 60 - +MN908947.3 8595 8619 nCoV-2019_29_LEFT 60 + +MN908947.3 8954 8983 nCoV-2019_29_RIGHT 60 - +MN908947.3 8888 8913 nCoV-2019_30_LEFT 60 + +MN908947.3 9245 9271 nCoV-2019_30_RIGHT 60 - +MN908947.3 9204 9226 nCoV-2019_31_LEFT 60 + +MN908947.3 9557 9585 nCoV-2019_31_RIGHT 60 - +MN908947.3 9477 9502 nCoV-2019_32_LEFT 60 + +MN908947.3 9834 9858 nCoV-2019_32_RIGHT 60 - +MN908947.3 9784 9806 nCoV-2019_33_LEFT 60 + +MN908947.3 10146 10171 nCoV-2019_33_RIGHT 60 - +MN908947.3 10076 10099 nCoV-2019_34_LEFT 60 + +MN908947.3 10437 10459 nCoV-2019_34_RIGHT 60 - +MN908947.3 10362 10384 nCoV-2019_35_LEFT 60 + +MN908947.3 10737 10763 nCoV-2019_35_RIGHT 60 - +MN908947.3 10666 10688 nCoV-2019_36_LEFT 60 + +MN908947.3 11048 11074 nCoV-2019_36_RIGHT 60 - +MN908947.3 10999 11022 nCoV-2019_37_LEFT 60 + +MN908947.3 11372 11394 nCoV-2019_37_RIGHT 60 - +MN908947.3 11306 11331 nCoV-2019_38_LEFT 60 + +MN908947.3 11668 11693 nCoV-2019_38_RIGHT 60 - +MN908947.3 11555 11584 nCoV-2019_39_LEFT 60 + +MN908947.3 11927 11949 nCoV-2019_39_RIGHT 60 - +MN908947.3 11863 11889 nCoV-2019_40_LEFT 60 + +MN908947.3 12234 12256 nCoV-2019_40_RIGHT 60 - +MN908947.3 12110 12133 nCoV-2019_41_LEFT 60 + +MN908947.3 12465 12490 nCoV-2019_41_RIGHT 60 - +MN908947.3 12417 12439 nCoV-2019_42_LEFT 60 + +MN908947.3 12779 12802 nCoV-2019_42_RIGHT 60 - +MN908947.3 12710 12732 nCoV-2019_43_LEFT 60 + +MN908947.3 13074 13096 nCoV-2019_43_RIGHT 60 - +MN908947.3 13005 13027 nCoV-2019_44_LEFT 60 + +MN908947.3 13378 13400 nCoV-2019_44_RIGHT 60 - +MN908947.3 13319 13344 nCoV-2019_45_LEFT 60 + +MN908947.3 13669 13699 nCoV-2019_45_RIGHT 60 - +MN908947.3 13599 13621 nCoV-2019_46_LEFT 60 + +MN908947.3 13962 13984 nCoV-2019_46_RIGHT 60 - +MN908947.3 13918 13946 nCoV-2019_47_LEFT 60 + +MN908947.3 14271 14299 nCoV-2019_47_RIGHT 60 - +MN908947.3 14207 14232 nCoV-2019_48_LEFT 60 + +MN908947.3 14579 14601 nCoV-2019_48_RIGHT 60 - +MN908947.3 14545 14570 nCoV-2019_49_LEFT 60 + +MN908947.3 14898 14926 nCoV-2019_49_RIGHT 60 - +MN908947.3 14865 14895 nCoV-2019_50_LEFT 60 + +MN908947.3 15224 15246 nCoV-2019_50_RIGHT 60 - +MN908947.3 15171 15193 nCoV-2019_51_LEFT 60 + +MN908947.3 15538 15560 nCoV-2019_51_RIGHT 60 - +MN908947.3 15481 15503 nCoV-2019_52_LEFT 60 + +MN908947.3 15861 15886 nCoV-2019_52_RIGHT 60 - +MN908947.3 15827 15851 nCoV-2019_53_LEFT 60 + +MN908947.3 16186 16209 nCoV-2019_53_RIGHT 60 - +MN908947.3 16118 16144 nCoV-2019_54_LEFT 60 + +MN908947.3 16485 16510 nCoV-2019_54_RIGHT 60 - +MN908947.3 16416 16444 nCoV-2019_55_LEFT 60 + +MN908947.3 16804 16833 nCoV-2019_55_RIGHT 60 - +MN908947.3 16748 16770 nCoV-2019_56_LEFT 60 + +MN908947.3 17130 17152 nCoV-2019_56_RIGHT 60 - +MN908947.3 17065 17087 nCoV-2019_57_LEFT 60 + +MN908947.3 17430 17452 nCoV-2019_57_RIGHT 60 - +MN908947.3 17381 17406 nCoV-2019_58_LEFT 60 + +MN908947.3 17738 17761 nCoV-2019_58_RIGHT 60 - +MN908947.3 17674 17697 nCoV-2019_59_LEFT 60 + +MN908947.3 18036 18062 nCoV-2019_59_RIGHT 60 - +MN908947.3 17966 17993 nCoV-2019_60_LEFT 60 + +MN908947.3 18324 18348 nCoV-2019_60_RIGHT 60 - +MN908947.3 18253 18275 nCoV-2019_61_LEFT 60 + +MN908947.3 18650 18672 nCoV-2019_61_RIGHT 60 - +MN908947.3 18596 18618 nCoV-2019_62_LEFT 60 + +MN908947.3 18957 18979 nCoV-2019_62_RIGHT 60 - +MN908947.3 18896 18918 nCoV-2019_63_LEFT 60 + +MN908947.3 19275 19297 nCoV-2019_63_RIGHT 60 - +MN908947.3 19204 19232 nCoV-2019_64_LEFT 60 + +MN908947.3 19591 19616 nCoV-2019_64_RIGHT 60 - +MN908947.3 19548 19570 nCoV-2019_65_LEFT 60 + +MN908947.3 19911 19939 nCoV-2019_65_RIGHT 60 - +MN908947.3 19844 19866 nCoV-2019_66_LEFT 60 + +MN908947.3 20231 20255 nCoV-2019_66_RIGHT 60 - +MN908947.3 20172 20200 nCoV-2019_67_LEFT 60 + +MN908947.3 20542 20572 nCoV-2019_67_RIGHT 60 - +MN908947.3 20472 20496 nCoV-2019_68_LEFT 60 + +MN908947.3 20867 20890 nCoV-2019_68_RIGHT 60 - +MN908947.3 20786 20813 nCoV-2019_69_LEFT 60 + +MN908947.3 21146 21169 nCoV-2019_69_RIGHT 60 - +MN908947.3 21075 21104 nCoV-2019_70_LEFT 60 + +MN908947.3 21427 21455 nCoV-2019_70_RIGHT 60 - +MN908947.3 21357 21386 nCoV-2019_71_LEFT 60 + +MN908947.3 21716 21743 nCoV-2019_71_RIGHT 60 - +MN908947.3 21658 21682 nCoV-2019_72_LEFT 60 + +MN908947.3 22013 22038 nCoV-2019_72_RIGHT 60 - +MN908947.3 21961 21990 nCoV-2019_73_LEFT 60 + +MN908947.3 22324 22346 nCoV-2019_73_RIGHT 60 - +MN908947.3 22262 22290 nCoV-2019_74_LEFT 60 + +MN908947.3 22626 22650 nCoV-2019_74_RIGHT 60 - +MN908947.3 22516 22542 nCoV-2019_75_LEFT 60 + +MN908947.3 22877 22903 nCoV-2019_75_RIGHT 60 - +MN908947.3 22797 22819 nCoV-2019_76_LEFT 60 + +MN908947.3 23192 23214 nCoV-2019_76_RIGHT 60 - +MN908947.3 23122 23144 nCoV-2019_77_LEFT 60 + +MN908947.3 23500 23522 nCoV-2019_77_RIGHT 60 - +MN908947.3 23443 23466 nCoV-2019_78_LEFT 60 + +MN908947.3 23822 23847 nCoV-2019_78_RIGHT 60 - +MN908947.3 23789 23812 nCoV-2019_79_LEFT 60 + +MN908947.3 24145 24169 nCoV-2019_79_RIGHT 60 - +MN908947.3 24078 24100 nCoV-2019_80_LEFT 60 + +MN908947.3 24443 24467 nCoV-2019_80_RIGHT 60 - +MN908947.3 24391 24416 nCoV-2019_81_LEFT 60 + +MN908947.3 24765 24789 nCoV-2019_81_RIGHT 60 - +MN908947.3 24696 24721 nCoV-2019_82_LEFT 60 + +MN908947.3 25052 25076 nCoV-2019_82_RIGHT 60 - +MN908947.3 24978 25003 nCoV-2019_83_LEFT 60 + +MN908947.3 25347 25369 nCoV-2019_83_RIGHT 60 - +MN908947.3 25279 25301 nCoV-2019_84_LEFT 60 + +MN908947.3 25646 25673 nCoV-2019_84_RIGHT 60 - +MN908947.3 25601 25623 nCoV-2019_85_LEFT 60 + +MN908947.3 25969 25994 nCoV-2019_85_RIGHT 60 - +MN908947.3 25902 25924 nCoV-2019_86_LEFT 60 + +MN908947.3 26290 26315 nCoV-2019_86_RIGHT 60 - +MN908947.3 26197 26219 nCoV-2019_87_LEFT 60 + +MN908947.3 26566 26590 nCoV-2019_87_RIGHT 60 - +MN908947.3 26520 26542 nCoV-2019_88_LEFT 60 + +MN908947.3 26890 26913 nCoV-2019_88_RIGHT 60 - +MN908947.3 26835 26857 nCoV-2019_89_LEFT 60 + +MN908947.3 27202 27227 nCoV-2019_89_RIGHT 60 - +MN908947.3 27141 27164 nCoV-2019_90_LEFT 60 + +MN908947.3 27511 27533 nCoV-2019_90_RIGHT 60 - +MN908947.3 27446 27471 nCoV-2019_91_LEFT 60 + +MN908947.3 27825 27854 nCoV-2019_91_RIGHT 60 - +MN908947.3 27784 27808 nCoV-2019_92_LEFT 60 + +MN908947.3 28145 28172 nCoV-2019_92_RIGHT 60 - +MN908947.3 28081 28104 nCoV-2019_93_LEFT 60 + +MN908947.3 28442 28464 nCoV-2019_93_RIGHT 60 - +MN908947.3 28394 28416 nCoV-2019_94_LEFT 60 + +MN908947.3 28756 28779 nCoV-2019_94_RIGHT 60 - +MN908947.3 28677 28699 nCoV-2019_95_LEFT 60 + +MN908947.3 29041 29063 nCoV-2019_95_RIGHT 60 - +MN908947.3 28985 29007 nCoV-2019_96_LEFT 60 + +MN908947.3 29356 29378 nCoV-2019_96_RIGHT 60 - +MN908947.3 29288 29316 nCoV-2019_97_LEFT 60 + +MN908947.3 29665 29693 nCoV-2019_97_RIGHT 60 - +MN908947.3 29486 29510 nCoV-2019_98_LEFT 60 + +MN908947.3 29836 29866 nCoV-2019_98_RIGHT 60 - diff -r 000000000000 -r 7a82006f7c05 test-data/nCoV-2019.reference.fasta --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/nCoV-2019.reference.fasta Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,500 @@ +>MN908947.3 +ATTAAAGGTTTATACCTTCCCAGGTAACAAACCAACCAACTTTCGATCTCTTGTAGATCT +GTTCTCTAAACGAACTTTAAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACT +CACGCAGTATAATTAATAACTAATTACTGTCGTTGACAGGACACGAGTAACTCGTCTATC +TTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAGCACATCTAGGTTT +CGTCCGGGTGTGACCGAAAGGTAAGATGGAGAGCCTTGTCCCTGGTTTCAACGAGAAAAC +ACACGTCCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGG +AGACTCCGTGGAGGAGGTCTTATCAGAGGCACGTCAACATCTTAAAGATGGCACTTGTGG +CTTAGTAGAAGTTGAAAAAGGCGTTTTGCCTCAACTTGAACAGCCCTATGTGTTCATCAA +ACGTTCGGATGCTCGAACTGCACCTCATGGTCATGTTATGGTTGAGCTGGTAGCAGAACT +CGAAGGCATTCAGTACGGTCGTAGTGGTGAGACACTTGGTGTCCTTGTCCCTCATGTGGG +CGAAATACCAGTGGCTTACCGCAAGGTTCTTCTTCGTAAGAACGGTAATAAAGGAGCTGG +TGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGA +TCCTTATGAAGATTTTCAAGAAAACTGGAACACTAAACATAGCAGTGGTGTTACCCGTGA +ACTCATGCGTGAGCTTAACGGAGGGGCATACACTCGCTATGTCGATAACAACTTCTGTGG +CCCTGATGGCTACCCTCTTGAGTGCATTAAAGACCTTCTAGCACGTGCTGGTAAAGCTTC +ATGCACTTTGTCCGAACAACTGGACTTTATTGACACTAAGAGGGGTGTATACTGCTGCCG +TGAACATGAGCATGAAATTGCTTGGTACACGGAACGTTCTGAAAAGAGCTATGAATTGCA +GACACCTTTTGAAATTAAATTGGCAAAGAAATTTGACACCTTCAATGGGGAATGTCCAAA +TTTTGTATTTCCCTTAAATTCCATAATCAAGACTATTCAACCAAGGGTTGAAAAGAAAAA +GCTTGATGGCTTTATGGGTAGAATTCGATCTGTCTATCCAGTTGCGTCACCAAATGAATG +CAACCAAATGTGCCTTTCAACTCTCATGAAGTGTGATCATTGTGGTGAAACTTCATGGCA +GACGGGCGATTTTGTTAAAGCCACTTGCGAATTTTGTGGCACTGAGAATTTGACTAAAGA +AGGTGCCACTACTTGTGGTTACTTACCCCAAAATGCTGTTGTTAAAATTTATTGTCCAGC +ATGTCACAATTCAGAAGTAGGACCTGAGCATAGTCTTGCCGAATACCATAATGAATCTGG +CTTGAAAACCATTCTTCGTAAGGGTGGTCGCACTATTGCCTTTGGAGGCTGTGTGTTCTC +TTATGTTGGTTGCCATAACAAGTGTGCCTATTGGGTTCCACGTGCTAGCGCTAACATAGG +TTGTAACCATACAGGTGTTGTTGGAGAAGGTTCCGAAGGTCTTAATGACAACCTTCTTGA +AATACTCCAAAAAGAGAAAGTCAACATCAATATTGTTGGTGACTTTAAACTTAATGAAGA +GATCGCCATTATTTTGGCATCTTTTTCTGCTTCCACAAGTGCTTTTGTGGAAACTGTGAA +AGGTTTGGATTATAAAGCATTCAAACAAATTGTTGAATCCTGTGGTAATTTTAAAGTTAC +AAAAGGAAAAGCTAAAAAAGGTGCCTGGAATATTGGTGAACAGAAATCAATACTGAGTCC +TCTTTATGCATTTGCATCAGAGGCTGCTCGTGTTGTACGATCAATTTTCTCCCGCACTCT +TGAAACTGCTCAAAATTCTGTGCGTGTTTTACAGAAGGCCGCTATAACAATACTAGATGG +AATTTCACAGTATTCACTGAGACTCATTGATGCTATGATGTTCACATCTGATTTGGCTAC +TAACAATCTAGTTGTAATGGCCTACATTACAGGTGGTGTTGTTCAGTTGACTTCGCAGTG +GCTAACTAACATCTTTGGCACTGTTTATGAAAAACTCAAACCCGTCCTTGATTGGCTTGA +AGAGAAGTTTAAGGAAGGTGTAGAGTTTCTTAGAGACGGTTGGGAAATTGTTAAATTTAT +CTCAACCTGTGCTTGTGAAATTGTCGGTGGACAAATTGTCACCTGTGCAAAGGAAATTAA +GGAGAGTGTTCAGACATTCTTTAAGCTTGTAAATAAATTTTTGGCTTTGTGTGCTGACTC +TATCATTATTGGTGGAGCTAAACTTAAAGCCTTGAATTTAGGTGAAACATTTGTCACGCA +CTCAAAGGGATTGTACAGAAAGTGTGTTAAATCCAGAGAAGAAACTGGCCTACTCATGCC +TCTAAAAGCCCCAAAAGAAATTATCTTCTTAGAGGGAGAAACACTTCCCACAGAAGTGTT +AACAGAGGAAGTTGTCTTGAAAACTGGTGATTTACAACCATTAGAACAACCTACTAGTGA +AGCTGTTGAAGCTCCATTGGTTGGTACACCAGTTTGTATTAACGGGCTTATGTTGCTCGA +AATCAAAGACACAGAAAAGTACTGTGCCCTTGCACCTAATATGATGGTAACAAACAATAC +CTTCACACTCAAAGGCGGTGCACCAACAAAGGTTACTTTTGGTGATGACACTGTGATAGA +AGTGCAAGGTTACAAGAGTGTGAATATCACTTTTGAACTTGATGAAAGGATTGATAAAGT +ACTTAATGAGAAGTGCTCTGCCTATACAGTTGAACTCGGTACAGAAGTAAATGAGTTCGC +CTGTGTTGTGGCAGATGCTGTCATAAAAACTTTGCAACCAGTATCTGAATTACTTACACC +ACTGGGCATTGATTTAGATGAGTGGAGTATGGCTACATACTACTTATTTGATGAGTCTGG +TGAGTTTAAATTGGCTTCACATATGTATTGTTCTTTCTACCCTCCAGATGAGGATGAAGA +AGAAGGTGATTGTGAAGAAGAAGAGTTTGAGCCATCAACTCAATATGAGTATGGTACTGA +AGATGATTACCAAGGTAAACCTTTGGAATTTGGTGCCACTTCTGCTGCTCTTCAACCTGA +AGAAGAGCAAGAAGAAGATTGGTTAGATGATGATAGTCAACAAACTGTTGGTCAACAAGA +CGGCAGTGAGGACAATCAGACAACTACTATTCAAACAATTGTTGAGGTTCAACCTCAATT +AGAGATGGAACTTACACCAGTTGTTCAGACTATTGAAGTGAATAGTTTTAGTGGTTATTT +AAAACTTACTGACAATGTATACATTAAAAATGCAGACATTGTGGAAGAAGCTAAAAAGGT +AAAACCAACAGTGGTTGTTAATGCAGCCAATGTTTACCTTAAACATGGAGGAGGTGTTGC +AGGAGCCTTAAATAAGGCTACTAACAATGCCATGCAAGTTGAATCTGATGATTACATAGC +TACTAATGGACCACTTAAAGTGGGTGGTAGTTGTGTTTTAAGCGGACACAATCTTGCTAA +ACACTGTCTTCATGTTGTCGGCCCAAATGTTAACAAAGGTGAAGACATTCAACTTCTTAA +GAGTGCTTATGAAAATTTTAATCAGCACGAAGTTCTACTTGCACCATTATTATCAGCTGG +TATTTTTGGTGCTGACCCTATACATTCTTTAAGAGTTTGTGTAGATACTGTTCGCACAAA +TGTCTACTTAGCTGTCTTTGATAAAAATCTCTATGACAAACTTGTTTCAAGCTTTTTGGA +AATGAAGAGTGAAAAGCAAGTTGAACAAAAGATCGCTGAGATTCCTAAAGAGGAAGTTAA +GCCATTTATAACTGAAAGTAAACCTTCAGTTGAACAGAGAAAACAAGATGATAAGAAAAT +CAAAGCTTGTGTTGAAGAAGTTACAACAACTCTGGAAGAAACTAAGTTCCTCACAGAAAA +CTTGTTACTTTATATTGACATTAATGGCAATCTTCATCCAGATTCTGCCACTCTTGTTAG +TGACATTGACATCACTTTCTTAAAGAAAGATGCTCCATATATAGTGGGTGATGTTGTTCA +AGAGGGTGTTTTAACTGCTGTGGTTATACCTACTAAAAAGGCTGGTGGCACTACTGAAAT +GCTAGCGAAAGCTTTGAGAAAAGTGCCAACAGACAATTATATAACCACTTACCCGGGTCA +GGGTTTAAATGGTTACACTGTAGAGGAGGCAAAGACAGTGCTTAAAAAGTGTAAAAGTGC +CTTTTACATTCTACCATCTATTATCTCTAATGAGAAGCAAGAAATTCTTGGAACTGTTTC +TTGGAATTTGCGAGAAATGCTTGCACATGCAGAAGAAACACGCAAATTAATGCCTGTCTG +TGTGGAAACTAAAGCCATAGTTTCAACTATACAGCGTAAATATAAGGGTATTAAAATACA +AGAGGGTGTGGTTGATTATGGTGCTAGATTTTACTTTTACACCAGTAAAACAACTGTAGC +GTCACTTATCAACACACTTAACGATCTAAATGAAACTCTTGTTACAATGCCACTTGGCTA +TGTAACACATGGCTTAAATTTGGAAGAAGCTGCTCGGTATATGAGATCTCTCAAAGTGCC +AGCTACAGTTTCTGTTTCTTCACCTGATGCTGTTACAGCGTATAATGGTTATCTTACTTC +TTCTTCTAAAACACCTGAAGAACATTTTATTGAAACCATCTCACTTGCTGGTTCCTATAA +AGATTGGTCCTATTCTGGACAATCTACACAACTAGGTATAGAATTTCTTAAGAGAGGTGA +TAAAAGTGTATATTACACTAGTAATCCTACCACATTCCACCTAGATGGTGAAGTTATCAC +CTTTGACAATCTTAAGACACTTCTTTCTTTGAGAGAAGTGAGGACTATTAAGGTGTTTAC +AACAGTAGACAACATTAACCTCCACACGCAAGTTGTGGACATGTCAATGACATATGGACA +ACAGTTTGGTCCAACTTATTTGGATGGAGCTGATGTTACTAAAATAAAACCTCATAATTC +ACATGAAGGTAAAACATTTTATGTTTTACCTAATGATGACACTCTACGTGTTGAGGCTTT +TGAGTACTACCACACAACTGATCCTAGTTTTCTGGGTAGGTACATGTCAGCATTAAATCA +CACTAAAAAGTGGAAATACCCACAAGTTAATGGTTTAACTTCTATTAAATGGGCAGATAA +CAACTGTTATCTTGCCACTGCATTGTTAACACTCCAACAAATAGAGTTGAAGTTTAATCC +ACCTGCTCTACAAGATGCTTATTACAGAGCAAGGGCTGGTGAAGCTGCTAACTTTTGTGC +ACTTATCTTAGCCTACTGTAATAAGACAGTAGGTGAGTTAGGTGATGTTAGAGAAACAAT +GAGTTACTTGTTTCAACATGCCAATTTAGATTCTTGCAAAAGAGTCTTGAACGTGGTGTG +TAAAACTTGTGGACAACAGCAGACAACCCTTAAGGGTGTAGAAGCTGTTATGTACATGGG +CACACTTTCTTATGAACAATTTAAGAAAGGTGTTCAGATACCTTGTACGTGTGGTAAACA +AGCTACAAAATATCTAGTACAACAGGAGTCACCTTTTGTTATGATGTCAGCACCACCTGC +TCAGTATGAACTTAAGCATGGTACATTTACTTGTGCTAGTGAGTACACTGGTAATTACCA +GTGTGGTCACTATAAACATATAACTTCTAAAGAAACTTTGTATTGCATAGACGGTGCTTT +ACTTACAAAGTCCTCAGAATACAAAGGTCCTATTACGGATGTTTTCTACAAAGAAAACAG +TTACACAACAACCATAAAACCAGTTACTTATAAATTGGATGGTGTTGTTTGTACAGAAAT +TGACCCTAAGTTGGACAATTATTATAAGAAAGACAATTCTTATTTCACAGAGCAACCAAT +TGATCTTGTACCAAACCAACCATATCCAAACGCAAGCTTCGATAATTTTAAGTTTGTATG +TGATAATATCAAATTTGCTGATGATTTAAACCAGTTAACTGGTTATAAGAAACCTGCTTC +AAGAGAGCTTAAAGTTACATTTTTCCCTGACTTAAATGGTGATGTGGTGGCTATTGATTA +TAAACACTACACACCCTCTTTTAAGAAAGGAGCTAAATTGTTACATAAACCTATTGTTTG +GCATGTTAACAATGCAACTAATAAAGCCACGTATAAACCAAATACCTGGTGTATACGTTG +TCTTTGGAGCACAAAACCAGTTGAAACATCAAATTCGTTTGATGTACTGAAGTCAGAGGA +CGCGCAGGGAATGGATAATCTTGCCTGCGAAGATCTAAAACCAGTCTCTGAAGAAGTAGT +GGAAAATCCTACCATACAGAAAGACGTTCTTGAGTGTAATGTGAAAACTACCGAAGTTGT +AGGAGACATTATACTTAAACCAGCAAATAATAGTTTAAAAATTACAGAAGAGGTTGGCCA +CACAGATCTAATGGCTGCTTATGTAGACAATTCTAGTCTTACTATTAAGAAACCTAATGA +ATTATCTAGAGTATTAGGTTTGAAAACCCTTGCTACTCATGGTTTAGCTGCTGTTAATAG +TGTCCCTTGGGATACTATAGCTAATTATGCTAAGCCTTTTCTTAACAAAGTTGTTAGTAC +AACTACTAACATAGTTACACGGTGTTTAAACCGTGTTTGTACTAATTATATGCCTTATTT +CTTTACTTTATTGCTACAATTGTGTACTTTTACTAGAAGTACAAATTCTAGAATTAAAGC +ATCTATGCCGACTACTATAGCAAAGAATACTGTTAAGAGTGTCGGTAAATTTTGTCTAGA +GGCTTCATTTAATTATTTGAAGTCACCTAATTTTTCTAAACTGATAAATATTATAATTTG +GTTTTTACTATTAAGTGTTTGCCTAGGTTCTTTAATCTACTCAACCGCTGCTTTAGGTGT +TTTAATGTCTAATTTAGGCATGCCTTCTTACTGTACTGGTTACAGAGAAGGCTATTTGAA +CTCTACTAATGTCACTATTGCAACCTACTGTACTGGTTCTATACCTTGTAGTGTTTGTCT +TAGTGGTTTAGATTCTTTAGACACCTATCCTTCTTTAGAAACTATACAAATTACCATTTC +ATCTTTTAAATGGGATTTAACTGCTTTTGGCTTAGTTGCAGAGTGGTTTTTGGCATATAT +TCTTTTCACTAGGTTTTTCTATGTACTTGGATTGGCTGCAATCATGCAATTGTTTTTCAG +CTATTTTGCAGTACATTTTATTAGTAATTCTTGGCTTATGTGGTTAATAATTAATCTTGT +ACAAATGGCCCCGATTTCAGCTATGGTTAGAATGTACATCTTCTTTGCATCATTTTATTA +TGTATGGAAAAGTTATGTGCATGTTGTAGACGGTTGTAATTCATCAACTTGTATGATGTG +TTACAAACGTAATAGAGCAACAAGAGTCGAATGTACAACTATTGTTAATGGTGTTAGAAG +GTCCTTTTATGTCTATGCTAATGGAGGTAAAGGCTTTTGCAAACTACACAATTGGAATTG +TGTTAATTGTGATACATTCTGTGCTGGTAGTACATTTATTAGTGATGAAGTTGCGAGAGA +CTTGTCACTACAGTTTAAAAGACCAATAAATCCTACTGACCAGTCTTCTTACATCGTTGA +TAGTGTTACAGTGAAGAATGGTTCCATCCATCTTTACTTTGATAAAGCTGGTCAAAAGAC +TTATGAAAGACATTCTCTCTCTCATTTTGTTAACTTAGACAACCTGAGAGCTAATAACAC +TAAAGGTTCATTGCCTATTAATGTTATAGTTTTTGATGGTAAATCAAAATGTGAAGAATC +ATCTGCAAAATCAGCGTCTGTTTACTACAGTCAGCTTATGTGTCAACCTATACTGTTACT +AGATCAGGCATTAGTGTCTGATGTTGGTGATAGTGCGGAAGTTGCAGTTAAAATGTTTGA +TGCTTACGTTAATACGTTTTCATCAACTTTTAACGTACCAATGGAAAAACTCAAAACACT +AGTTGCAACTGCAGAAGCTGAACTTGCAAAGAATGTGTCCTTAGACAATGTCTTATCTAC +TTTTATTTCAGCAGCTCGGCAAGGGTTTGTTGATTCAGATGTAGAAACTAAAGATGTTGT +TGAATGTCTTAAATTGTCACATCAATCTGACATAGAAGTTACTGGCGATAGTTGTAATAA +CTATATGCTCACCTATAACAAAGTTGAAAACATGACACCCCGTGACCTTGGTGCTTGTAT +TGACTGTAGTGCGCGTCATATTAATGCGCAGGTAGCAAAAAGTCACAACATTGCTTTGAT +ATGGAACGTTAAAGATTTCATGTCATTGTCTGAACAACTACGAAAACAAATACGTAGTGC +TGCTAAAAAGAATAACTTACCTTTTAAGTTGACATGTGCAACTACTAGACAAGTTGTTAA +TGTTGTAACAACAAAGATAGCACTTAAGGGTGGTAAAATTGTTAATAATTGGTTGAAGCA +GTTAATTAAAGTTACACTTGTGTTCCTTTTTGTTGCTGCTATTTTCTATTTAATAACACC +TGTTCATGTCATGTCTAAACATACTGACTTTTCAAGTGAAATCATAGGATACAAGGCTAT +TGATGGTGGTGTCACTCGTGACATAGCATCTACAGATACTTGTTTTGCTAACAAACATGC +TGATTTTGACACATGGTTTAGCCAGCGTGGTGGTAGTTATACTAATGACAAAGCTTGCCC +ATTGATTGCTGCAGTCATAACAAGAGAAGTGGGTTTTGTCGTGCCTGGTTTGCCTGGCAC +GATATTACGCACAACTAATGGTGACTTTTTGCATTTCTTACCTAGAGTTTTTAGTGCAGT +TGGTAACATCTGTTACACACCATCAAAACTTATAGAGTACACTGACTTTGCAACATCAGC +TTGTGTTTTGGCTGCTGAATGTACAATTTTTAAAGATGCTTCTGGTAAGCCAGTACCATA +TTGTTATGATACCAATGTACTAGAAGGTTCTGTTGCTTATGAAAGTTTACGCCCTGACAC +ACGTTATGTGCTCATGGATGGCTCTATTATTCAATTTCCTAACACCTACCTTGAAGGTTC +TGTTAGAGTGGTAACAACTTTTGATTCTGAGTACTGTAGGCACGGCACTTGTGAAAGATC +AGAAGCTGGTGTTTGTGTATCTACTAGTGGTAGATGGGTACTTAACAATGATTATTACAG +ATCTTTACCAGGAGTTTTCTGTGGTGTAGATGCTGTAAATTTACTTACTAATATGTTTAC +ACCACTAATTCAACCTATTGGTGCTTTGGACATATCAGCATCTATAGTAGCTGGTGGTAT +TGTAGCTATCGTAGTAACATGCCTTGCCTACTATTTTATGAGGTTTAGAAGAGCTTTTGG +TGAATACAGTCATGTAGTTGCCTTTAATACTTTACTATTCCTTATGTCATTCACTGTACT +CTGTTTAACACCAGTTTACTCATTCTTACCTGGTGTTTATTCTGTTATTTACTTGTACTT +GACATTTTATCTTACTAATGATGTTTCTTTTTTAGCACATATTCAGTGGATGGTTATGTT +CACACCTTTAGTACCTTTCTGGATAACAATTGCTTATATCATTTGTATTTCCACAAAGCA +TTTCTATTGGTTCTTTAGTAATTACCTAAAGAGACGTGTAGTCTTTAATGGTGTTTCCTT +TAGTACTTTTGAAGAAGCTGCGCTGTGCACCTTTTTGTTAAATAAAGAAATGTATCTAAA +GTTGCGTAGTGATGTGCTATTACCTCTTACGCAATATAATAGATACTTAGCTCTTTATAA +TAAGTACAAGTATTTTAGTGGAGCAATGGATACAACTAGCTACAGAGAAGCTGCTTGTTG +TCATCTCGCAAAGGCTCTCAATGACTTCAGTAACTCAGGTTCTGATGTTCTTTACCAACC +ACCACAAACCTCTATCACCTCAGCTGTTTTGCAGAGTGGTTTTAGAAAAATGGCATTCCC +ATCTGGTAAAGTTGAGGGTTGTATGGTACAAGTAACTTGTGGTACAACTACACTTAACGG +TCTTTGGCTTGATGACGTAGTTTACTGTCCAAGACATGTGATCTGCACCTCTGAAGACAT +GCTTAACCCTAATTATGAAGATTTACTCATTCGTAAGTCTAATCATAATTTCTTGGTACA +GGCTGGTAATGTTCAACTCAGGGTTATTGGACATTCTATGCAAAATTGTGTACTTAAGCT +TAAGGTTGATACAGCCAATCCTAAGACACCTAAGTATAAGTTTGTTCGCATTCAACCAGG +ACAGACTTTTTCAGTGTTAGCTTGTTACAATGGTTCACCATCTGGTGTTTACCAATGTGC +TATGAGGCCCAATTTCACTATTAAGGGTTCATTCCTTAATGGTTCATGTGGTAGTGTTGG +TTTTAACATAGATTATGACTGTGTCTCTTTTTGTTACATGCACCATATGGAATTACCAAC +TGGAGTTCATGCTGGCACAGACTTAGAAGGTAACTTTTATGGACCTTTTGTTGACAGGCA +AACAGCACAAGCAGCTGGTACGGACACAACTATTACAGTTAATGTTTTAGCTTGGTTGTA +CGCTGCTGTTATAAATGGAGACAGGTGGTTTCTCAATCGATTTACCACAACTCTTAATGA +CTTTAACCTTGTGGCTATGAAGTACAATTATGAACCTCTAACACAAGACCATGTTGACAT +ACTAGGACCTCTTTCTGCTCAAACTGGAATTGCCGTTTTAGATATGTGTGCTTCATTAAA +AGAATTACTGCAAAATGGTATGAATGGACGTACCATATTGGGTAGTGCTTTATTAGAAGA +TGAATTTACACCTTTTGATGTTGTTAGACAATGCTCAGGTGTTACTTTCCAAAGTGCAGT +GAAAAGAACAATCAAGGGTACACACCACTGGTTGTTACTCACAATTTTGACTTCACTTTT +AGTTTTAGTCCAGAGTACTCAATGGTCTTTGTTCTTTTTTTTGTATGAAAATGCCTTTTT +ACCTTTTGCTATGGGTATTATTGCTATGTCTGCTTTTGCAATGATGTTTGTCAAACATAA +GCATGCATTTCTCTGTTTGTTTTTGTTACCTTCTCTTGCCACTGTAGCTTATTTTAATAT +GGTCTATATGCCTGCTAGTTGGGTGATGCGTATTATGACATGGTTGGATATGGTTGATAC +TAGTTTGTCTGGTTTTAAGCTAAAAGACTGTGTTATGTATGCATCAGCTGTAGTGTTACT +AATCCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAGAGTGTGGACACTTAT +GAATGTCTTGACACTCGTTTATAAAGTTTATTATGGTAATGCTTTAGATCAAGCCATTTC +CATGTGGGCTCTTATAATCTCTGTTACTTCTAACTACTCAGGTGTAGTTACAACTGTCAT +GTTTTTGGCCAGAGGTATTGTTTTTATGTGTGTTGAGTATTGCCCTATTTTCTTCATAAC +TGGTAATACACTTCAGTGTATAATGCTAGTTTATTGTTTCTTAGGCTATTTTTGTACTTG +TTACTTTGGCCTCTTTTGTTTACTCAACCGCTACTTTAGACTGACTCTTGGTGTTTATGA +TTACTTAGTTTCTACACAGGAGTTTAGATATATGAATTCACAGGGACTACTCCCACCCAA +GAATAGCATAGATGCCTTCAAACTCAACATTAAATTGTTGGGTGTTGGTGGCAAACCTTG +TATCAAAGTAGCCACTGTACAGTCTAAAATGTCAGATGTAAAGTGCACATCAGTAGTCTT +ACTCTCAGTTTTGCAACAACTCAGAGTAGAATCATCATCTAAATTGTGGGCTCAATGTGT +CCAGTTACACAATGACATTCTCTTAGCTAAAGATACTACTGAAGCCTTTGAAAAAATGGT +TTCACTACTTTCTGTTTTGCTTTCCATGCAGGGTGCTGTAGACATAAACAAGCTTTGTGA +AGAAATGCTGGACAACAGGGCAACCTTACAAGCTATAGCCTCAGAGTTTAGTTCCCTTCC +ATCATATGCAGCTTTTGCTACTGCTCAAGAAGCTTATGAGCAGGCTGTTGCTAATGGTGA +TTCTGAAGTTGTTCTTAAAAAGTTGAAGAAGTCTTTGAATGTGGCTAAATCTGAATTTGA +CCGTGATGCAGCCATGCAACGTAAGTTGGAAAAGATGGCTGATCAAGCTATGACCCAAAT +GTATAAACAGGCTAGATCTGAGGACAAGAGGGCAAAAGTTACTAGTGCTATGCAGACAAT +GCTTTTCACTATGCTTAGAAAGTTGGATAATGATGCACTCAACAACATTATCAACAATGC +AAGAGATGGTTGTGTTCCCTTGAACATAATACCTCTTACAACAGCAGCCAAACTAATGGT +TGTCATACCAGACTATAACACATATAAAAATACGTGTGATGGTACAACATTTACTTATGC +ATCAGCATTGTGGGAAATCCAACAGGTTGTAGATGCAGATAGTAAAATTGTTCAACTTAG +TGAAATTAGTATGGACAATTCACCTAATTTAGCATGGCCTCTTATTGTAACAGCTTTAAG +GGCCAATTCTGCTGTCAAATTACAGAATAATGAGCTTAGTCCTGTTGCACTACGACAGAT +GTCTTGTGCTGCCGGTACTACACAAACTGCTTGCACTGATGACAATGCGTTAGCTTACTA +CAACACAACAAAGGGAGGTAGGTTTGTACTTGCACTGTTATCCGATTTACAGGATTTGAA +ATGGGCTAGATTCCCTAAGAGTGATGGAACTGGTACTATCTATACAGAACTGGAACCACC +TTGTAGGTTTGTTACAGACACACCTAAAGGTCCTAAAGTGAAGTATTTATACTTTATTAA +AGGATTAAACAACCTAAATAGAGGTATGGTACTTGGTAGTTTAGCTGCCACAGTACGTCT +ACAAGCTGGTAATGCAACAGAAGTGCCTGCCAATTCAACTGTATTATCTTTCTGTGCTTT +TGCTGTAGATGCTGCTAAAGCTTACAAAGATTATCTAGCTAGTGGGGGACAACCAATCAC +TAATTGTGTTAAGATGTTGTGTACACACACTGGTACTGGTCAGGCAATAACAGTTACACC +GGAAGCCAATATGGATCAAGAATCCTTTGGTGGTGCATCGTGTTGTCTGTACTGCCGTTG +CCACATAGATCATCCAAATCCTAAAGGATTTTGTGACTTAAAAGGTAAGTATGTACAAAT +ACCTACAACTTGTGCTAATGACCCTGTGGGTTTTACACTTAAAAACACAGTCTGTACCGT +CTGCGGTATGTGGAAAGGTTATGGCTGTAGTTGTGATCAACTCCGCGAACCCATGCTTCA +GTCAGCTGATGCACAATCGTTTTTAAACGGGTTTGCGGTGTAAGTGCAGCCCGTCTTACA +CCGTGCGGCACAGGCACTAGTACTGATGTCGTATACAGGGCTTTTGACATCTACAATGAT +AAAGTAGCTGGTTTTGCTAAATTCCTAAAAACTAATTGTTGTCGCTTCCAAGAAAAGGAC +GAAGATGACAATTTAATTGATTCTTACTTTGTAGTTAAGAGACACACTTTCTCTAACTAC +CAACATGAAGAAACAATTTATAATTTACTTAAGGATTGTCCAGCTGTTGCTAAACATGAC +TTCTTTAAGTTTAGAATAGACGGTGACATGGTACCACATATATCACGTCAACGTCTTACT +AAATACACAATGGCAGACCTCGTCTATGCTTTAAGGCATTTTGATGAAGGTAATTGTGAC +ACATTAAAAGAAATACTTGTCACATACAATTGTTGTGATGATGATTATTTCAATAAAAAG +GACTGGTATGATTTTGTAGAAAACCCAGATATATTACGCGTATACGCCAACTTAGGTGAA +CGTGTACGCCAAGCTTTGTTAAAAACAGTACAATTCTGTGATGCCATGCGAAATGCTGGT +ATTGTTGGTGTACTGACATTAGATAATCAAGATCTCAATGGTAACTGGTATGATTTCGGT +GATTTCATACAAACCACGCCAGGTAGTGGAGTTCCTGTTGTAGATTCTTATTATTCATTG +TTAATGCCTATATTAACCTTGACCAGGGCTTTAACTGCAGAGTCACATGTTGACACTGAC +TTAACAAAGCCTTACATTAAGTGGGATTTGTTAAAATATGACTTCACGGAAGAGAGGTTA +AAACTCTTTGACCGTTATTTTAAATATTGGGATCAGACATACCACCCAAATTGTGTTAAC +TGTTTGGATGACAGATGCATTCTGCATTGTGCAAACTTTAATGTTTTATTCTCTACAGTG +TTCCCACCTACAAGTTTTGGACCACTAGTGAGAAAAATATTTGTTGATGGTGTTCCATTT +GTAGTTTCAACTGGATACCACTTCAGAGAGCTAGGTGTTGTACATAATCAGGATGTAAAC +TTACATAGCTCTAGACTTAGTTTTAAGGAATTACTTGTGTATGCTGCTGACCCTGCTATG +CACGCTGCTTCTGGTAATCTATTACTAGATAAACGCACTACGTGCTTTTCAGTAGCTGCA +CTTACTAACAATGTTGCTTTTCAAACTGTCAAACCCGGTAATTTTAACAAAGACTTCTAT +GACTTTGCTGTGTCTAAGGGTTTCTTTAAGGAAGGAAGTTCTGTTGAATTAAAACACTTC +TTCTTTGCTCAGGATGGTAATGCTGCTATCAGCGATTATGACTACTATCGTTATAATCTA +CCAACAATGTGTGATATCAGACAACTACTATTTGTAGTTGAAGTTGTTGATAAGTACTTT +GATTGTTACGATGGTGGCTGTATTAATGCTAACCAAGTCATCGTCAACAACCTAGACAAA +TCAGCTGGTTTTCCATTTAATAAATGGGGTAAGGCTAGACTTTATTATGATTCAATGAGT +TATGAGGATCAAGATGCACTTTTCGCATATACAAAACGTAATGTCATCCCTACTATAACT +CAAATGAATCTTAAGTATGCCATTAGTGCAAAGAATAGAGCTCGCACCGTAGCTGGTGTC +TCTATCTGTAGTACTATGACCAATAGACAGTTTCATCAAAAATTATTGAAATCAATAGCC +GCCACTAGAGGAGCTACTGTAGTAATTGGAACAAGCAAATTCTATGGTGGTTGGCACAAC +ATGTTAAAAACTGTTTATAGTGATGTAGAAAACCCTCACCTTATGGGTTGGGATTATCCT +AAATGTGATAGAGCCATGCCTAACATGCTTAGAATTATGGCCTCACTTGTTCTTGCTCGC +AAACATACAACGTGTTGTAGCTTGTCACACCGTTTCTATAGATTAGCTAATGAGTGTGCT +CAAGTATTGAGTGAAATGGTCATGTGTGGCGGTTCACTATATGTTAAACCAGGTGGAACC +TCATCAGGAGATGCCACAACTGCTTATGCTAATAGTGTTTTTAACATTTGTCAAGCTGTC +ACGGCCAATGTTAATGCACTTTTATCTACTGATGGTAACAAAATTGCCGATAAGTATGTC +CGCAATTTACAACACAGACTTTATGAGTGTCTCTATAGAAATAGAGATGTTGACACAGAC +TTTGTGAATGAGTTTTACGCATATTTGCGTAAACATTTCTCAATGATGATACTCTCTGAC +GATGCTGTTGTGTGTTTCAATAGCACTTATGCATCTCAAGGTCTAGTGGCTAGCATAAAG +AACTTTAAGTCAGTTCTTTATTATCAAAACAATGTTTTTATGTCTGAAGCAAAATGTTGG +ACTGAGACTGACCTTACTAAAGGACCTCATGAATTTTGCTCTCAACATACAATGCTAGTT +AAACAGGGTGATGATTATGTGTACCTTCCTTACCCAGATCCATCAAGAATCCTAGGGGCC +GGCTGTTTTGTAGATGATATCGTAAAAACAGATGGTACACTTATGATTGAACGGTTCGTG +TCTTTAGCTATAGATGCTTACCCACTTACTAAACATCCTAATCAGGAGTATGCTGATGTC +TTTCATTTGTACTTACAATACATAAGAAAGCTACATGATGAGTTAACAGGACACATGTTA +GACATGTATTCTGTTATGCTTACTAATGATAACACTTCAAGGTATTGGGAACCTGAGTTT +TATGAGGCTATGTACACACCGCATACAGTCTTACAGGCTGTTGGGGCTTGTGTTCTTTGC +AATTCACAGACTTCATTAAGATGTGGTGCTTGCATACGTAGACCATTCTTATGTTGTAAA +TGCTGTTACGACCATGTCATATCAACATCACATAAATTAGTCTTGTCTGTTAATCCGTAT +GTTTGCAATGCTCCAGGTTGTGATGTCACAGATGTGACTCAACTTTACTTAGGAGGTATG +AGCTATTATTGTAAATCACATAAACCACCCATTAGTTTTCCATTGTGTGCTAATGGACAA +GTTTTTGGTTTATATAAAAATACATGTGTTGGTAGCGATAATGTTACTGACTTTAATGCA +ATTGCAACATGTGACTGGACAAATGCTGGTGATTACATTTTAGCTAACACCTGTACTGAA +AGACTCAAGCTTTTTGCAGCAGAAACGCTCAAAGCTACTGAGGAGACATTTAAACTGTCT +TATGGTATTGCTACTGTACGTGAAGTGCTGTCTGACAGAGAATTACATCTTTCATGGGAA +GTTGGTAAACCTAGACCACCACTTAACCGAAATTATGTCTTTACTGGTTATCGTGTAACT +AAAAACAGTAAAGTACAAATAGGAGAGTACACCTTTGAAAAAGGTGACTATGGTGATGCT +GTTGTTTACCGAGGTACAACAACTTACAAATTAAATGTTGGTGATTATTTTGTGCTGACA +TCACATACAGTAATGCCATTAAGTGCACCTACACTAGTGCCACAAGAGCACTATGTTAGA +ATTACTGGCTTATACCCAACACTCAATATCTCAGATGAGTTTTCTAGCAATGTTGCAAAT +TATCAAAAGGTTGGTATGCAAAAGTATTCTACACTCCAGGGACCACCTGGTACTGGTAAG +AGTCATTTTGCTATTGGCCTAGCTCTCTACTACCCTTCTGCTCGCATAGTGTATACAGCT +TGCTCTCATGCCGCTGTTGATGCACTATGTGAGAAGGCATTAAAATATTTGCCTATAGAT +AAATGTAGTAGAATTATACCTGCACGTGCTCGTGTAGAGTGTTTTGATAAATTCAAAGTG +AATTCAACATTAGAACAGTATGTCTTTTGTACTGTAAATGCATTGCCTGAGACGACAGCA +GATATAGTTGTCTTTGATGAAATTTCAATGGCCACAAATTATGATTTGAGTGTTGTCAAT +GCCAGATTACGTGCTAAGCACTATGTGTACATTGGCGACCCTGCTCAATTACCTGCACCA +CGCACATTGCTAACTAAGGGCACACTAGAACCAGAATATTTCAATTCAGTGTGTAGACTT +ATGAAAACTATAGGTCCAGACATGTTCCTCGGAACTTGTCGGCGTTGTCCTGCTGAAATT +GTTGACACTGTGAGTGCTTTGGTTTATGATAATAAGCTTAAAGCACATAAAGACAAATCA +GCTCAATGCTTTAAAATGTTTTATAAGGGTGTTATCACGCATGATGTTTCATCTGCAATT +AACAGGCCACAAATAGGCGTGGTAAGAGAATTCCTTACACGTAACCCTGCTTGGAGAAAA +GCTGTCTTTATTTCACCTTATAATTCACAGAATGCTGTAGCCTCAAAGATTTTGGGACTA +CCAACTCAAACTGTTGATTCATCACAGGGCTCAGAATATGACTATGTCATATTCACTCAA +ACCACTGAAACAGCTCACTCTTGTAATGTAAACAGATTTAATGTTGCTATTACCAGAGCA +AAAGTAGGCATACTTTGCATAATGTCTGATAGAGACCTTTATGACAAGTTGCAATTTACA +AGTCTTGAAATTCCACGTAGGAATGTGGCAACTTTACAAGCTGAAAATGTAACAGGACTC +TTTAAAGATTGTAGTAAGGTAATCACTGGGTTACATCCTACACAGGCACCTACACACCTC +AGTGTTGACACTAAATTCAAAACTGAAGGTTTATGTGTTGACATACCTGGCATACCTAAG +GACATGACCTATAGAAGACTCATCTCTATGATGGGTTTTAAAATGAATTATCAAGTTAAT +GGTTACCCTAACATGTTTATCACCCGCGAAGAAGCTATAAGACATGTACGTGCATGGATT +GGCTTCGATGTCGAGGGGTGTCATGCTACTAGAGAAGCTGTTGGTACCAATTTACCTTTA +CAGCTAGGTTTTTCTACAGGTGTTAACCTAGTTGCTGTACCTACAGGTTATGTTGATACA +CCTAATAATACAGATTTTTCCAGAGTTAGTGCTAAACCACCGCCTGGAGATCAATTTAAA +CACCTCATACCACTTATGTACAAAGGACTTCCTTGGAATGTAGTGCGTATAAAGATTGTA +CAAATGTTAAGTGACACACTTAAAAATCTCTCTGACAGAGTCGTATTTGTCTTATGGGCA +CATGGCTTTGAGTTGACATCTATGAAGTATTTTGTGAAAATAGGACCTGAGCGCACCTGT +TGTCTATGTGATAGACGTGCCACATGCTTTTCCACTGCTTCAGACACTTATGCCTGTTGG +CATCATTCTATTGGATTTGATTACGTCTATAATCCGTTTATGATTGATGTTCAACAATGG +GGTTTTACAGGTAACCTACAAAGCAACCATGATCTGTATTGTCAAGTCCATGGTAATGCA +CATGTAGCTAGTTGTGATGCAATCATGACTAGGTGTCTAGCTGTCCACGAGTGCTTTGTT +AAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCG +GCTTGTAGAAAGGTTCAACACATGGTTGTTAAAGCTGCATTATTAGCAGACAAATTCCCA +GTTCTTCACGACATTGGTAACCCTAAAGCTATTAAGTGTGTACCTCAAGCTGATGTAGAA +TGGAAGTTCTATGATGCACAGCCTTGTAGTGACAAAGCTTATAAAATAGAAGAATTATTC +TATTCTTATGCCACACATTCTGACAAATTCACAGATGGTGTATGCCTATTTTGGAATTGC +AATGTCGATAGATATCCTGCTAATTCCATTGTTTGTAGATTTGACACTAGAGTGCTATCT +AACCTTAACTTGCCTGGTTGTGATGGTGGCAGTTTGTATGTAAATAAACATGCATTCCAC +ACACCAGCTTTTGATAAAAGTGCTTTTGTTAATTTAAAACAATTACCATTTTTCTATTAC +TCTGACAGTCCATGTGAGTCTCATGGAAAACAAGTAGTGTCAGATATAGATTATGTACCA +CTAAAGTCTGCTACGTGTATAACACGTTGCAATTTAGGTGGTGCTGTCTGTAGACATCAT +GCTAATGAGTACAGATTGTATCTCGATGCTTATAACATGATGATCTCAGCTGGCTTTAGC +TTGTGGGTTTACAAACAATTTGATACTTATAACCTCTGGAACACTTTTACAAGACTTCAG +AGTTTAGAAAATGTGGCTTTTAATGTTGTAAATAAGGGACACTTTGATGGACAACAGGGT +GAAGTACCAGTTTCTATCATTAATAACACTGTTTACACAAAAGTTGATGGTGTTGATGTA +GAATTGTTTGAAAATAAAACAACATTACCTGTTAATGTAGCATTTGAGCTTTGGGCTAAG +CGCAACATTAAACCAGTACCAGAGGTGAAAATACTCAATAATTTGGGTGTGGACATTGCT +GCTAATACTGTGATCTGGGACTACAAAAGAGATGCTCCAGCACATATATCTACTATTGGT +GTTTGTTCTATGACTGACATAGCCAAGAAACCAACTGAAACGATTTGTGCACCACTCACT +GTCTTTTTTGATGGTAGAGTTGATGGTCAAGTAGACTTATTTAGAAATGCCCGTAATGGT +GTTCTTATTACAGAAGGTAGTGTTAAAGGTTTACAACCATCTGTAGGTCCCAAACAAGCT +AGTCTTAATGGAGTCACATTAATTGGAGAAGCCGTAAAAACACAGTTCAATTATTATAAG +AAAGTTGATGGTGTTGTCCAACAATTACCTGAAACTTACTTTACTCAGAGTAGAAATTTA +CAAGAATTTAAACCCAGGAGTCAAATGGAAATTGATTTCTTAGAATTAGCTATGGATGAA +TTCATTGAACGGTATAAATTAGAAGGCTATGCCTTCGAACATATCGTTTATGGAGATTTT +AGTCATAGTCAGTTAGGTGGTTTACATCTACTGATTGGACTAGCTAAACGTTTTAAGGAA +TCACCTTTTGAATTAGAAGATTTTATTCCTATGGACAGTACAGTTAAAAACTATTTCATA +ACAGATGCGCAAACAGGTTCATCTAAGTGTGTGTGTTCTGTTATTGATTTATTACTTGAT +GATTTTGTTGAAATAATAAAATCCCAAGATTTATCTGTAGTTTCTAAGGTTGTCAAAGTG +ACTATTGACTATACAGAAATTTCATTTATGCTTTGGTGTAAAGATGGCCATGTAGAAACA +TTTTACCCAAAATTACAATCTAGTCAAGCGTGGCAACCGGGTGTTGCTATGCCTAATCTT +TACAAAATGCAAAGAATGCTATTAGAAAAGTGTGACCTTCAAAATTATGGTGATAGTGCA +ACATTACCTAAAGGCATAATGATGAATGTCGCAAAATATACTCAACTGTGTCAATATTTA +AACACATTAACATTAGCTGTACCCTATAATATGAGAGTTATACATTTTGGTGCTGGTTCT +GATAAAGGAGTTGCACCAGGTACAGCTGTTTTAAGACAGTGGTTGCCTACGGGTACGCTG +CTTGTCGATTCAGATCTTAATGACTTTGTCTCTGATGCAGATTCAACTTTGATTGGTGAT +TGTGCAACTGTACATACAGCTAATAAATGGGATCTCATTATTAGTGATATGTACGACCCT +AAGACTAAAAATGTTACAAAAGAAAATGACTCTAAAGAGGGTTTTTTCACTTACATTTGT +GGGTTTATACAACAAAAGCTAGCTCTTGGAGGTTCCGTGGCTATAAAGATAACAGAACAT +TCTTGGAATGCTGATCTTTATAAGCTCATGGGACACTTCGCATGGTGGACAGCCTTTGTT +ACTAATGTGAATGCGTCATCATCTGAAGCATTTTTAATTGGATGTAATTATCTTGGCAAA +CCACGCGAACAAATAGATGGTTATGTCATGCATGCAAATTACATATTTTGGAGGAATACA +AATCCAATTCAGTTGTCTTCCTATTCTTTATTTGACATGAGTAAATTTCCCCTTAAATTA +AGGGGTACTGCTGTTATGTCTTTAAAAGAAGGTCAAATCAATGATATGATTTTATCTCTT +CTTAGTAAAGGTAGACTTATAATTAGAGAAAACAACAGAGTTGTTATTTCTAGTGATGTT +CTTGTTAACAACTAAACGAACAATGTTTGTTTTTCTTGTTTTATTGCCACTAGTCTCTAG +TCAGTGTGTTAATCTTACAACCAGAACTCAATTACCCCCTGCATACACTAATTCTTTCAC +ACGTGGTGTTTATTACCCTGACAAAGTTTTCAGATCCTCAGTTTTACATTCAACTCAGGA +CTTGTTCTTACCTTTCTTTTCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGAC +CAATGGTACTAAGAGGTTTGATAACCCTGTCCTACCATTTAATGATGGTGTTTATTTTGC +TTCCACTGAGAAGTCTAACATAATAAGAGGCTGGATTTTTGGTACTACTTTAGATTCGAA +GACCCAGTCCCTACTTATTGTTAATAACGCTACTAATGTTGTTATTAAAGTCTGTGAATT +TCAATTTTGTAATGATCCATTTTTGGGTGTTTATTACCACAAAAACAACAAAAGTTGGAT +GGAAAGTGAGTTCAGAGTTTATTCTAGTGCGAATAATTGCACTTTTGAATATGTCTCTCA +GCCTTTTCTTATGGACCTTGAAGGAAAACAGGGTAATTTCAAAAATCTTAGGGAATTTGT +GTTTAAGAATATTGATGGTTATTTTAAAATATATTCTAAGCACACGCCTATTAATTTAGT +GCGTGATCTCCCTCAGGGTTTTTCGGCTTTAGAACCATTGGTAGATTTGCCAATAGGTAT +TAACATCACTAGGTTTCAAACTTTACTTGCTTTACATAGAAGTTATTTGACTCCTGGTGA +TTCTTCTTCAGGTTGGACAGCTGGTGCTGCAGCTTATTATGTGGGTTATCTTCAACCTAG +GACTTTTCTATTAAAATATAATGAAAATGGAACCATTACAGATGCTGTAGACTGTGCACT +TGACCCTCTCTCAGAAACAAAGTGTACGTTGAAATCCTTCACTGTAGAAAAAGGAATCTA +TCAAACTTCTAACTTTAGAGTCCAACCAACAGAATCTATTGTTAGATTTCCTAATATTAC +AAACTTGTGCCCTTTTGGTGAAGTTTTTAACGCCACCAGATTTGCATCTGTTTATGCTTG +GAACAGGAAGAGAATCAGCAACTGTGTTGCTGATTATTCTGTCCTATATAATTCCGCATC +ATTTTCCACTTTTAAGTGTTATGGAGTGTCTCCTACTAAATTAAATGATCTCTGCTTTAC +TAATGTCTATGCAGATTCATTTGTAATTAGAGGTGATGAAGTCAGACAAATCGCTCCAGG +GCAAACTGGAAAGATTGCTGATTATAATTATAAATTACCAGATGATTTTACAGGCTGCGT +TATAGCTTGGAATTCTAACAATCTTGATTCTAAGGTTGGTGGTAATTATAATTACCTGTA +TAGATTGTTTAGGAAGTCTAATCTCAAACCTTTTGAGAGAGATATTTCAACTGAAATCTA +TCAGGCCGGTAGCACACCTTGTAATGGTGTTGAAGGTTTTAATTGTTACTTTCCTTTACA +ATCATATGGTTTCCAACCCACTAATGGTGTTGGTTACCAACCATACAGAGTAGTAGTACT +TTCTTTTGAACTTCTACATGCACCAGCAACTGTTTGTGGACCTAAAAAGTCTACTAATTT +GGTTAAAAACAAATGTGTCAATTTCAACTTCAATGGTTTAACAGGCACAGGTGTTCTTAC +TGAGTCTAACAAAAAGTTTCTGCCTTTCCAACAATTTGGCAGAGACATTGCTGACACTAC +TGATGCTGTCCGTGATCCACAGACACTTGAGATTCTTGACATTACACCATGTTCTTTTGG +TGGTGTCAGTGTTATAACACCAGGAACAAATACTTCTAACCAGGTTGCTGTTCTTTATCA +GGATGTTAACTGCACAGAAGTCCCTGTTGCTATTCATGCAGATCAACTTACTCCTACTTG +GCGTGTTTATTCTACAGGTTCTAATGTTTTTCAAACACGTGCAGGCTGTTTAATAGGGGC +TGAACATGTCAACAACTCATATGAGTGTGACATACCCATTGGTGCAGGTATATGCGCTAG +TTATCAGACTCAGACTAATTCTCCTCGGCGGGCACGTAGTGTAGCTAGTCAATCCATCAT +TGCCTACACTATGTCACTTGGTGCAGAAAATTCAGTTGCTTACTCTAATAACTCTATTGC +CATACCCACAAATTTTACTATTAGTGTTACCACAGAAATTCTACCAGTGTCTATGACCAA +GACATCAGTAGATTGTACAATGTACATTTGTGGTGATTCAACTGAATGCAGCAATCTTTT +GTTGCAATATGGCAGTTTTTGTACACAATTAAACCGTGCTTTAACTGGAATAGCTGTTGA +ACAAGACAAAAACACCCAAGAAGTTTTTGCACAAGTCAAACAAATTTACAAAACACCACC +AATTAAAGATTTTGGTGGTTTTAATTTTTCACAAATATTACCAGATCCATCAAAACCAAG +CAAGAGGTCATTTATTGAAGATCTACTTTTCAACAAAGTGACACTTGCAGATGCTGGCTT +CATCAAACAATATGGTGATTGCCTTGGTGATATTGCTGCTAGAGACCTCATTTGTGCACA +AAAGTTTAACGGCCTTACTGTTTTGCCACCTTTGCTCACAGATGAAATGATTGCTCAATA +CACTTCTGCACTGTTAGCGGGTACAATCACTTCTGGTTGGACCTTTGGTGCAGGTGCTGC +ATTACAAATACCATTTGCTATGCAAATGGCTTATAGGTTTAATGGTATTGGAGTTACACA +GAATGTTCTCTATGAGAACCAAAAATTGATTGCCAACCAATTTAATAGTGCTATTGGCAA +AATTCAAGACTCACTTTCTTCCACAGCAAGTGCACTTGGAAAACTTCAAGATGTGGTCAA +CCAAAATGCACAAGCTTTAAACACGCTTGTTAAACAACTTAGCTCCAATTTTGGTGCAAT +TTCAAGTGTTTTAAATGATATCCTTTCACGTCTTGACAAAGTTGAGGCTGAAGTGCAAAT +TGATAGGTTGATCACAGGCAGACTTCAAAGTTTGCAGACATATGTGACTCAACAATTAAT +TAGAGCTGCAGAAATCAGAGCTTCTGCTAATCTTGCTGCTACTAAAATGTCAGAGTGTGT +ACTTGGACAATCAAAAAGAGTTGATTTTTGTGGAAAGGGCTATCATCTTATGTCCTTCCC +TCAGTCAGCACCTCATGGTGTAGTCTTCTTGCATGTGACTTATGTCCCTGCACAAGAAAA +GAACTTCACAACTGCTCCTGCCATTTGTCATGATGGAAAAGCACACTTTCCTCGTGAAGG +TGTCTTTGTTTCAAATGGCACACACTGGTTTGTAACACAAAGGAATTTTTATGAACCACA +AATCATTACTACAGACAACACATTTGTGTCTGGTAACTGTGATGTTGTAATAGGAATTGT +CAACAACACAGTTTATGATCCTTTGCAACCTGAATTAGACTCATTCAAGGAGGAGTTAGA +TAAATATTTTAAGAATCATACATCACCAGATGTTGATTTAGGTGACATCTCTGGCATTAA +TGCTTCAGTTGTAAACATTCAAAAAGAAATTGACCGCCTCAATGAGGTTGCCAAGAATTT +AAATGAATCTCTCATCGATCTCCAAGAACTTGGAAAGTATGAGCAGTATATAAAATGGCC +ATGGTACATTTGGCTAGGTTTTATAGCTGGCTTGATTGCCATAGTAATGGTGACAATTAT +GCTTTGCTGTATGACCAGTTGCTGTAGTTGTCTCAAGGGCTGTTGTTCTTGTGGATCCTG +CTGCAAATTTGATGAAGACGACTCTGAGCCAGTGCTCAAAGGAGTCAAATTACATTACAC +ATAAACGAACTTATGGATTTGTTTATGAGAATCTTCACAATTGGAACTGTAACTTTGAAG +CAAGGTGAAATCAAGGATGCTACTCCTTCAGATTTTGTTCGCGCTACTGCAACGATACCG +ATACAAGCCTCACTCCCTTTCGGATGGCTTATTGTTGGCGTTGCACTTCTTGCTGTTTTT +CAGAGCGCTTCCAAAATCATAACCCTCAAAAAGAGATGGCAACTAGCACTCTCCAAGGGT +GTTCACTTTGTTTGCAACTTGCTGTTGTTGTTTGTAACAGTTTACTCACACCTTTTGCTC +GTTGCTGCTGGCCTTGAAGCCCCTTTTCTCTATCTTTATGCTTTAGTCTACTTCTTGCAG +AGTATAAACTTTGTAAGAATAATAATGAGGCTTTGGCTTTGCTGGAAATGCCGTTCCAAA +AACCCATTACTTTATGATGCCAACTATTTTCTTTGCTGGCATACTAATTGTTACGACTAT +TGTATACCTTACAATAGTGTAACTTCTTCAATTGTCATTACTTCAGGTGATGGCACAACA +AGTCCTATTTCTGAACATGACTACCAGATTGGTGGTTATACTGAAAAATGGGAATCTGGA +GTAAAAGACTGTGTTGTATTACACAGTTACTTCACTTCAGACTATTACCAGCTGTACTCA +ACTCAATTGAGTACAGACACTGGTGTTGAACATGTTACCTTCTTCATCTACAATAAAATT +GTTGATGAGCCTGAAGAACATGTCCAAATTCACACAATCGACGGTTCATCCGGAGTTGTT +AATCCAGTAATGGAACCAATTTATGATGAACCGACGACGACTACTAGCGTGCCTTTGTAA +GCACAAGCTGATGAGTACGAACTTATGTACTCATTCGTTTCGGAAGAGACAGGTACGTTA +ATAGTTAATAGCGTACTTCTTTTTCTTGCTTTCGTGGTATTCTTGCTAGTTACACTAGCC +ATCCTTACTGCGCTTCGATTGTGTGCGTACTGCTGCAATATTGTTAACGTGAGTCTTGTA +AAACCTTCTTTTTACGTTTACTCTCGTGTTAAAAATCTGAATTCTTCTAGAGTTCCTGAT +CTTCTGGTCTAAACGAACTAAATATTATATTAGTTTTTCTGTTTGGAACTTTAATTTTAG +CCATGGCAGATTCCAACGGTACTATTACCGTTGAAGAGCTTAAAAAGCTCCTTGAACAAT +GGAACCTAGTAATAGGTTTCCTATTCCTTACATGGATTTGTCTTCTACAATTTGCCTATG +CCAACAGGAATAGGTTTTTGTATATAATTAAGTTAATTTTCCTCTGGCTGTTATGGCCAG +TAACTTTAGCTTGTTTTGTGCTTGCTGCTGTTTACAGAATAAATTGGATCACCGGTGGAA +TTGCTATCGCAATGGCTTGTCTTGTAGGCTTGATGTGGCTCAGCTACTTCATTGCTTCTT +TCAGACTGTTTGCGCGTACGCGTTCCATGTGGTCATTCAATCCAGAAACTAACATTCTTC +TCAACGTGCCACTCCATGGCACTATTCTGACCAGACCGCTTCTAGAAAGTGAACTCGTAA +TCGGAGCTGTGATCCTTCGTGGACATCTTCGTATTGCTGGACACCATCTAGGACGCTGTG +ACATCAAGGACCTGCCTAAAGAAATCACTGTTGCTACATCACGAACGCTTTCTTATTACA +AATTGGGAGCTTCGCAGCGTGTAGCAGGTGACTCAGGTTTTGCTGCATACAGTCGCTACA +GGATTGGCAACTATAAATTAAACACAGACCATTCCAGTAGCAGTGACAATATTGCTTTGC +TTGTACAGTAAGTGACAACAGATGTTTCATCTCGTTGACTTTCAGGTTACTATAGCAGAG +ATATTACTAATTATTATGAGGACTTTTAAAGTTTCCATTTGGAATCTTGATTACATCATA +AACCTCATAATTAAAAATTTATCTAAGTCACTAACTGAGAATAAATATTCTCAATTAGAT +GAAGAGCAACCAATGGAGATTGATTAAACGAACATGAAAATTATTCTTTTCTTGGCACTG +ATAACACTCGCTACTTGTGAGCTTTATCACTACCAAGAGTGTGTTAGAGGTACAACAGTA +CTTTTAAAAGAACCTTGCTCTTCTGGAACATACGAGGGCAATTCACCATTTCATCCTCTA +GCTGATAACAAATTTGCACTGACTTGCTTTAGCACTCAATTTGCTTTTGCTTGTCCTGAC +GGCGTAAAACACGTCTATCAGTTACGTGCCAGATCAGTTTCACCTAAACTGTTCATCAGA +CAAGAGGAAGTTCAAGAACTTTACTCTCCAATTTTTCTTATTGTTGCGGCAATAGTGTTT +ATAACACTTTGCTTCACACTCAAAAGAAAGACAGAATGATTGAACTTTCATTAATTGACT +TCTATTTGTGCTTTTTAGCCTTTCTGCTATTCCTTGTTTTAATTATGCTTATTATCTTTT +GGTTCTCACTTGAACTGCAAGATCATAATGAAACTTGTCACGCCTAAACGAACATGAAAT +TTCTTGTTTTCTTAGGAATCATCACAACTGTAGCTGCATTTCACCAAGAATGTAGTTTAC +AGTCATGTACTCAACATCAACCATATGTAGTTGATGACCCGTGTCCTATTCACTTCTATT +CTAAATGGTATATTAGAGTAGGAGCTAGAAAATCAGCACCTTTAATTGAATTGTGCGTGG +ATGAGGCTGGTTCTAAATCACCCATTCAGTACATCGATATCGGTAATTATACAGTTTCCT +GTTTACCTTTTACAATTAATTGCCAGGAACCTAAATTGGGTAGTCTTGTAGTGCGTTGTT +CGTTCTATGAAGACTTTTTAGAGTATCATGACGTTCGTGTTGTTTTAGATTTCATCTAAA +CGAACAAACTAAAATGTCTGATAATGGACCCCAAAATCAGCGAAATGCACCCCGCATTAC +GTTTGGTGGACCCTCAGATTCAACTGGCAGTAACCAGAATGGAGAACGCAGTGGGGCGCG +ATCAAAACAACGTCGGCCCCAAGGTTTACCCAATAATACTGCGTCTTGGTTCACCGCTCT +CACTCAACATGGCAAGGAAGACCTTAAATTCCCTCGAGGACAAGGCGTTCCAATTAACAC +CAATAGCAGTCCAGATGACCAAATTGGCTACTACCGAAGAGCTACCAGACGAATTCGTGG +TGGTGACGGTAAAATGAAAGATCTCAGTCCAAGATGGTATTTCTACTACCTAGGAACTGG +GCCAGAAGCTGGACTTCCCTATGGTGCTAACAAAGACGGCATCATATGGGTTGCAACTGA +GGGAGCCTTGAATACACCAAAAGATCACATTGGCACCCGCAATCCTGCTAACAATGCTGC +AATCGTGCTACAACTTCCTCAAGGAACAACATTGCCAAAAGGCTTCTACGCAGAAGGGAG +CAGAGGCGGCAGTCAAGCCTCTTCTCGTTCCTCATCACGTAGTCGCAACAGTTCAAGAAA +TTCAACTCCAGGCAGCAGTAGGGGAACTTCTCCTGCTAGAATGGCTGGCAATGGCGGTGA +TGCTGCTCTTGCTTTGCTGCTGCTTGACAGATTGAACCAGCTTGAGAGCAAAATGTCTGG +TAAAGGCCAACAACAACAAGGCCAAACTGTCACTAAGAAATCTGCTGCTGAGGCTTCTAA +GAAGCCTCGGCAAAAACGTACTGCCACTAAAGCATACAATGTAACACAAGCTTTCGGCAG +ACGTGGTCCAGAACAAACCCAAGGAAATTTTGGGGACCAGGAACTAATCAGACAAGGAAC +TGATTACAAACATTGGCCGCAAATTGCACAATTTGCCCCCAGCGCTTCAGCGTTCTTCGG +AATGTCGCGCATTGGCATGGAAGTCACACCTTCGGGAACGTGGTTGACCTACACAGGTGC +CATCAAATTGGATGACAAAGATCCAAATTTCAAAGATCAAGTCATTTTGCTGAATAAGCA +TATTGACGCATACAAAACATTCCCACCAACAGAGCCTAAAAAGGACAAAAAGAAGAAGGC +TGATGAAACTCAAGCCTTACCGCAGAGACAGAAGAAACAGCAAACTGTGACTCTTCTTCC +TGCTGCAGATTTGGATGATTTCTCCAAACAATTGCAACAATCCATGAGCAGTGCTGACTC +AACTCAGGCCTAAACTCATGCAGACCACACAAGGCAGATGGGCTATATAAACGTTTTCGC +TTTTCCGTTTACGATATATAGTCTACTCTTGTGCAGAATGAATTCTCGTAACTACATAGC +ACAAGTAGATGTAGTTAACTTTAATCTCACATAGCAATCTTTAATCAGTGTGTAACATTA +GGGAGGACTTGAAAGAGCCACCACATTTTCACCGAGGCCACGCGGAGTACGATCGAGTGT +ACAGTGAACAATGCTAGGGAGAGCTGCCTATATGGAAGAGCCCTAATGTGTAAAATTAAT +TTTAGTAGTGCTATCCCCATGTGATTTTAATAGCTTCTTAGGAGAATGACAAAAAAAAAA +AAAAAAAAAAAAAAAAAAAAAAA diff -r 000000000000 -r 7a82006f7c05 test-data/nCoV-2019.scheme.V1.bed --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/nCoV-2019.scheme.V1.bed Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,196 @@ +MN908947.3 30 54 nCoV-2019_1_LEFT nCoV-2019_1 +MN908947.3 385 410 nCoV-2019_1_RIGHT nCoV-2019_1 +MN908947.3 320 342 nCoV-2019_2_LEFT nCoV-2019_2 +MN908947.3 704 726 nCoV-2019_2_RIGHT nCoV-2019_2 +MN908947.3 642 664 nCoV-2019_3_LEFT nCoV-2019_1 +MN908947.3 1004 1028 nCoV-2019_3_RIGHT nCoV-2019_1 +MN908947.3 943 965 nCoV-2019_4_LEFT nCoV-2019_2 +MN908947.3 1312 1337 nCoV-2019_4_RIGHT nCoV-2019_2 +MN908947.3 1242 1264 nCoV-2019_5_LEFT nCoV-2019_1 +MN908947.3 1623 1651 nCoV-2019_5_RIGHT nCoV-2019_1 +MN908947.3 1573 1595 nCoV-2019_6_LEFT nCoV-2019_2 +MN908947.3 1942 1964 nCoV-2019_6_RIGHT nCoV-2019_2 +MN908947.3 1875 1897 nCoV-2019_7_LEFT nCoV-2019_1 +MN908947.3 2247 2269 nCoV-2019_7_RIGHT nCoV-2019_1 +MN908947.3 2181 2205 nCoV-2019_8_LEFT nCoV-2019_2 +MN908947.3 2568 2592 nCoV-2019_8_RIGHT nCoV-2019_2 +MN908947.3 2505 2529 nCoV-2019_9_LEFT nCoV-2019_1 +MN908947.3 2882 2904 nCoV-2019_9_RIGHT nCoV-2019_1 +MN908947.3 2826 2850 nCoV-2019_10_LEFT nCoV-2019_2 +MN908947.3 3183 3210 nCoV-2019_10_RIGHT nCoV-2019_2 +MN908947.3 3144 3166 nCoV-2019_11_LEFT nCoV-2019_1 +MN908947.3 3507 3531 nCoV-2019_11_RIGHT nCoV-2019_1 +MN908947.3 3460 3482 nCoV-2019_12_LEFT nCoV-2019_2 +MN908947.3 3826 3853 nCoV-2019_12_RIGHT nCoV-2019_2 +MN908947.3 3771 3795 nCoV-2019_13_LEFT nCoV-2019_1 +MN908947.3 4142 4164 nCoV-2019_13_RIGHT nCoV-2019_1 +MN908947.3 4054 4077 nCoV-2019_14_LEFT nCoV-2019_2 +MN908947.3 4428 4450 nCoV-2019_14_RIGHT nCoV-2019_2 +MN908947.3 4294 4321 nCoV-2019_15_LEFT nCoV-2019_1 +MN908947.3 4674 4696 nCoV-2019_15_RIGHT nCoV-2019_1 +MN908947.3 4636 4658 nCoV-2019_16_LEFT nCoV-2019_2 +MN908947.3 4995 5017 nCoV-2019_16_RIGHT nCoV-2019_2 +MN908947.3 4939 4966 nCoV-2019_17_LEFT nCoV-2019_1 +MN908947.3 5296 5321 nCoV-2019_17_RIGHT nCoV-2019_1 +MN908947.3 5230 5259 nCoV-2019_18_LEFT nCoV-2019_2 +MN908947.3 5620 5644 nCoV-2019_18_RIGHT nCoV-2019_2 +MN908947.3 5563 5586 nCoV-2019_19_LEFT nCoV-2019_1 +MN908947.3 5932 5957 nCoV-2019_19_RIGHT nCoV-2019_1 +MN908947.3 5867 5894 nCoV-2019_20_LEFT nCoV-2019_2 +MN908947.3 6247 6272 nCoV-2019_20_RIGHT nCoV-2019_2 +MN908947.3 6167 6196 nCoV-2019_21_LEFT nCoV-2019_1 +MN908947.3 6528 6550 nCoV-2019_21_RIGHT nCoV-2019_1 +MN908947.3 6466 6495 nCoV-2019_22_LEFT nCoV-2019_2 +MN908947.3 6846 6873 nCoV-2019_22_RIGHT nCoV-2019_2 +MN908947.3 6718 6745 nCoV-2019_23_LEFT nCoV-2019_1 +MN908947.3 7092 7117 nCoV-2019_23_RIGHT nCoV-2019_1 +MN908947.3 7035 7058 nCoV-2019_24_LEFT nCoV-2019_2 +MN908947.3 7389 7415 nCoV-2019_24_RIGHT nCoV-2019_2 +MN908947.3 7305 7332 nCoV-2019_25_LEFT nCoV-2019_1 +MN908947.3 7671 7694 nCoV-2019_25_RIGHT nCoV-2019_1 +MN908947.3 7626 7651 nCoV-2019_26_LEFT nCoV-2019_2 +MN908947.3 7997 8019 nCoV-2019_26_RIGHT nCoV-2019_2 +MN908947.3 7943 7968 nCoV-2019_27_LEFT nCoV-2019_1 +MN908947.3 8319 8341 nCoV-2019_27_RIGHT nCoV-2019_1 +MN908947.3 8249 8275 nCoV-2019_28_LEFT nCoV-2019_2 +MN908947.3 8635 8661 nCoV-2019_28_RIGHT nCoV-2019_2 +MN908947.3 8595 8619 nCoV-2019_29_LEFT nCoV-2019_1 +MN908947.3 8954 8983 nCoV-2019_29_RIGHT nCoV-2019_1 +MN908947.3 8888 8913 nCoV-2019_30_LEFT nCoV-2019_2 +MN908947.3 9245 9271 nCoV-2019_30_RIGHT nCoV-2019_2 +MN908947.3 9204 9226 nCoV-2019_31_LEFT nCoV-2019_1 +MN908947.3 9557 9585 nCoV-2019_31_RIGHT nCoV-2019_1 +MN908947.3 9477 9502 nCoV-2019_32_LEFT nCoV-2019_2 +MN908947.3 9834 9858 nCoV-2019_32_RIGHT nCoV-2019_2 +MN908947.3 9784 9806 nCoV-2019_33_LEFT nCoV-2019_1 +MN908947.3 10146 10171 nCoV-2019_33_RIGHT nCoV-2019_1 +MN908947.3 10076 10099 nCoV-2019_34_LEFT nCoV-2019_2 +MN908947.3 10437 10459 nCoV-2019_34_RIGHT nCoV-2019_2 +MN908947.3 10362 10384 nCoV-2019_35_LEFT nCoV-2019_1 +MN908947.3 10737 10763 nCoV-2019_35_RIGHT nCoV-2019_1 +MN908947.3 10666 10688 nCoV-2019_36_LEFT nCoV-2019_2 +MN908947.3 11048 11074 nCoV-2019_36_RIGHT nCoV-2019_2 +MN908947.3 10999 11022 nCoV-2019_37_LEFT nCoV-2019_1 +MN908947.3 11372 11394 nCoV-2019_37_RIGHT nCoV-2019_1 +MN908947.3 11306 11331 nCoV-2019_38_LEFT nCoV-2019_2 +MN908947.3 11668 11693 nCoV-2019_38_RIGHT nCoV-2019_2 +MN908947.3 11555 11584 nCoV-2019_39_LEFT nCoV-2019_1 +MN908947.3 11927 11949 nCoV-2019_39_RIGHT nCoV-2019_1 +MN908947.3 11863 11889 nCoV-2019_40_LEFT nCoV-2019_2 +MN908947.3 12234 12256 nCoV-2019_40_RIGHT nCoV-2019_2 +MN908947.3 12110 12133 nCoV-2019_41_LEFT nCoV-2019_1 +MN908947.3 12465 12490 nCoV-2019_41_RIGHT nCoV-2019_1 +MN908947.3 12417 12439 nCoV-2019_42_LEFT nCoV-2019_2 +MN908947.3 12779 12802 nCoV-2019_42_RIGHT nCoV-2019_2 +MN908947.3 12710 12732 nCoV-2019_43_LEFT nCoV-2019_1 +MN908947.3 13074 13096 nCoV-2019_43_RIGHT nCoV-2019_1 +MN908947.3 13005 13027 nCoV-2019_44_LEFT nCoV-2019_2 +MN908947.3 13378 13400 nCoV-2019_44_RIGHT nCoV-2019_2 +MN908947.3 13319 13344 nCoV-2019_45_LEFT nCoV-2019_1 +MN908947.3 13669 13699 nCoV-2019_45_RIGHT nCoV-2019_1 +MN908947.3 13599 13621 nCoV-2019_46_LEFT nCoV-2019_2 +MN908947.3 13962 13984 nCoV-2019_46_RIGHT nCoV-2019_2 +MN908947.3 13918 13946 nCoV-2019_47_LEFT nCoV-2019_1 +MN908947.3 14271 14299 nCoV-2019_47_RIGHT nCoV-2019_1 +MN908947.3 14207 14232 nCoV-2019_48_LEFT nCoV-2019_2 +MN908947.3 14579 14601 nCoV-2019_48_RIGHT nCoV-2019_2 +MN908947.3 14545 14570 nCoV-2019_49_LEFT nCoV-2019_1 +MN908947.3 14898 14926 nCoV-2019_49_RIGHT nCoV-2019_1 +MN908947.3 14865 14895 nCoV-2019_50_LEFT nCoV-2019_2 +MN908947.3 15224 15246 nCoV-2019_50_RIGHT nCoV-2019_2 +MN908947.3 15171 15193 nCoV-2019_51_LEFT nCoV-2019_1 +MN908947.3 15538 15560 nCoV-2019_51_RIGHT nCoV-2019_1 +MN908947.3 15481 15503 nCoV-2019_52_LEFT nCoV-2019_2 +MN908947.3 15861 15886 nCoV-2019_52_RIGHT nCoV-2019_2 +MN908947.3 15827 15851 nCoV-2019_53_LEFT nCoV-2019_1 +MN908947.3 16186 16209 nCoV-2019_53_RIGHT nCoV-2019_1 +MN908947.3 16118 16144 nCoV-2019_54_LEFT nCoV-2019_2 +MN908947.3 16485 16510 nCoV-2019_54_RIGHT nCoV-2019_2 +MN908947.3 16416 16444 nCoV-2019_55_LEFT nCoV-2019_1 +MN908947.3 16804 16833 nCoV-2019_55_RIGHT nCoV-2019_1 +MN908947.3 16748 16770 nCoV-2019_56_LEFT nCoV-2019_2 +MN908947.3 17130 17152 nCoV-2019_56_RIGHT nCoV-2019_2 +MN908947.3 17065 17087 nCoV-2019_57_LEFT nCoV-2019_1 +MN908947.3 17430 17452 nCoV-2019_57_RIGHT nCoV-2019_1 +MN908947.3 17381 17406 nCoV-2019_58_LEFT nCoV-2019_2 +MN908947.3 17738 17761 nCoV-2019_58_RIGHT nCoV-2019_2 +MN908947.3 17674 17697 nCoV-2019_59_LEFT nCoV-2019_1 +MN908947.3 18036 18062 nCoV-2019_59_RIGHT nCoV-2019_1 +MN908947.3 17966 17993 nCoV-2019_60_LEFT nCoV-2019_2 +MN908947.3 18324 18348 nCoV-2019_60_RIGHT nCoV-2019_2 +MN908947.3 18253 18275 nCoV-2019_61_LEFT nCoV-2019_1 +MN908947.3 18650 18672 nCoV-2019_61_RIGHT nCoV-2019_1 +MN908947.3 18596 18618 nCoV-2019_62_LEFT nCoV-2019_2 +MN908947.3 18957 18979 nCoV-2019_62_RIGHT nCoV-2019_2 +MN908947.3 18896 18918 nCoV-2019_63_LEFT nCoV-2019_1 +MN908947.3 19275 19297 nCoV-2019_63_RIGHT nCoV-2019_1 +MN908947.3 19204 19232 nCoV-2019_64_LEFT nCoV-2019_2 +MN908947.3 19591 19616 nCoV-2019_64_RIGHT nCoV-2019_2 +MN908947.3 19548 19570 nCoV-2019_65_LEFT nCoV-2019_1 +MN908947.3 19911 19939 nCoV-2019_65_RIGHT nCoV-2019_1 +MN908947.3 19844 19866 nCoV-2019_66_LEFT nCoV-2019_2 +MN908947.3 20231 20255 nCoV-2019_66_RIGHT nCoV-2019_2 +MN908947.3 20172 20200 nCoV-2019_67_LEFT nCoV-2019_1 +MN908947.3 20542 20572 nCoV-2019_67_RIGHT nCoV-2019_1 +MN908947.3 20472 20496 nCoV-2019_68_LEFT nCoV-2019_2 +MN908947.3 20867 20890 nCoV-2019_68_RIGHT nCoV-2019_2 +MN908947.3 20786 20813 nCoV-2019_69_LEFT nCoV-2019_1 +MN908947.3 21146 21169 nCoV-2019_69_RIGHT nCoV-2019_1 +MN908947.3 21075 21104 nCoV-2019_70_LEFT nCoV-2019_2 +MN908947.3 21427 21455 nCoV-2019_70_RIGHT nCoV-2019_2 +MN908947.3 21357 21386 nCoV-2019_71_LEFT nCoV-2019_1 +MN908947.3 21716 21743 nCoV-2019_71_RIGHT nCoV-2019_1 +MN908947.3 21658 21682 nCoV-2019_72_LEFT nCoV-2019_2 +MN908947.3 22013 22038 nCoV-2019_72_RIGHT nCoV-2019_2 +MN908947.3 21961 21990 nCoV-2019_73_LEFT nCoV-2019_1 +MN908947.3 22324 22346 nCoV-2019_73_RIGHT nCoV-2019_1 +MN908947.3 22262 22290 nCoV-2019_74_LEFT nCoV-2019_2 +MN908947.3 22626 22650 nCoV-2019_74_RIGHT nCoV-2019_2 +MN908947.3 22516 22542 nCoV-2019_75_LEFT nCoV-2019_1 +MN908947.3 22877 22903 nCoV-2019_75_RIGHT nCoV-2019_1 +MN908947.3 22797 22819 nCoV-2019_76_LEFT nCoV-2019_2 +MN908947.3 23192 23214 nCoV-2019_76_RIGHT nCoV-2019_2 +MN908947.3 23122 23144 nCoV-2019_77_LEFT nCoV-2019_1 +MN908947.3 23500 23522 nCoV-2019_77_RIGHT nCoV-2019_1 +MN908947.3 23443 23466 nCoV-2019_78_LEFT nCoV-2019_2 +MN908947.3 23822 23847 nCoV-2019_78_RIGHT nCoV-2019_2 +MN908947.3 23789 23812 nCoV-2019_79_LEFT nCoV-2019_1 +MN908947.3 24145 24169 nCoV-2019_79_RIGHT nCoV-2019_1 +MN908947.3 24078 24100 nCoV-2019_80_LEFT nCoV-2019_2 +MN908947.3 24443 24467 nCoV-2019_80_RIGHT nCoV-2019_2 +MN908947.3 24391 24416 nCoV-2019_81_LEFT nCoV-2019_1 +MN908947.3 24765 24789 nCoV-2019_81_RIGHT nCoV-2019_1 +MN908947.3 24696 24721 nCoV-2019_82_LEFT nCoV-2019_2 +MN908947.3 25052 25076 nCoV-2019_82_RIGHT nCoV-2019_2 +MN908947.3 24978 25003 nCoV-2019_83_LEFT nCoV-2019_1 +MN908947.3 25347 25369 nCoV-2019_83_RIGHT nCoV-2019_1 +MN908947.3 25279 25301 nCoV-2019_84_LEFT nCoV-2019_2 +MN908947.3 25646 25673 nCoV-2019_84_RIGHT nCoV-2019_2 +MN908947.3 25601 25623 nCoV-2019_85_LEFT nCoV-2019_1 +MN908947.3 25969 25994 nCoV-2019_85_RIGHT nCoV-2019_1 +MN908947.3 25902 25924 nCoV-2019_86_LEFT nCoV-2019_2 +MN908947.3 26290 26315 nCoV-2019_86_RIGHT nCoV-2019_2 +MN908947.3 26197 26219 nCoV-2019_87_LEFT nCoV-2019_1 +MN908947.3 26566 26590 nCoV-2019_87_RIGHT nCoV-2019_1 +MN908947.3 26520 26542 nCoV-2019_88_LEFT nCoV-2019_2 +MN908947.3 26890 26913 nCoV-2019_88_RIGHT nCoV-2019_2 +MN908947.3 26835 26857 nCoV-2019_89_LEFT nCoV-2019_1 +MN908947.3 27202 27227 nCoV-2019_89_RIGHT nCoV-2019_1 +MN908947.3 27141 27164 nCoV-2019_90_LEFT nCoV-2019_2 +MN908947.3 27511 27533 nCoV-2019_90_RIGHT nCoV-2019_2 +MN908947.3 27446 27471 nCoV-2019_91_LEFT nCoV-2019_1 +MN908947.3 27825 27854 nCoV-2019_91_RIGHT nCoV-2019_1 +MN908947.3 27784 27808 nCoV-2019_92_LEFT nCoV-2019_2 +MN908947.3 28145 28172 nCoV-2019_92_RIGHT nCoV-2019_2 +MN908947.3 28081 28104 nCoV-2019_93_LEFT nCoV-2019_1 +MN908947.3 28442 28464 nCoV-2019_93_RIGHT nCoV-2019_1 +MN908947.3 28394 28416 nCoV-2019_94_LEFT nCoV-2019_2 +MN908947.3 28756 28779 nCoV-2019_94_RIGHT nCoV-2019_2 +MN908947.3 28677 28699 nCoV-2019_95_LEFT nCoV-2019_1 +MN908947.3 29041 29063 nCoV-2019_95_RIGHT nCoV-2019_1 +MN908947.3 28985 29007 nCoV-2019_96_LEFT nCoV-2019_2 +MN908947.3 29356 29378 nCoV-2019_96_RIGHT nCoV-2019_2 +MN908947.3 29288 29316 nCoV-2019_97_LEFT nCoV-2019_1 +MN908947.3 29665 29693 nCoV-2019_97_RIGHT nCoV-2019_1 +MN908947.3 29486 29510 nCoV-2019_98_LEFT nCoV-2019_2 +MN908947.3 29836 29866 nCoV-2019_98_RIGHT nCoV-2019_2 diff -r 000000000000 -r 7a82006f7c05 test-data/nCoV-2019.scheme.V3.bed --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/nCoV-2019.scheme.V3.bed Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,218 @@ +MN908947.3 30 54 nCoV-2019_1_LEFT nCoV-2019_1 +MN908947.3 385 410 nCoV-2019_1_RIGHT nCoV-2019_1 +MN908947.3 320 342 nCoV-2019_2_LEFT nCoV-2019_2 +MN908947.3 704 726 nCoV-2019_2_RIGHT nCoV-2019_2 +MN908947.3 642 664 nCoV-2019_3_LEFT nCoV-2019_1 +MN908947.3 1004 1028 nCoV-2019_3_RIGHT nCoV-2019_1 +MN908947.3 943 965 nCoV-2019_4_LEFT nCoV-2019_2 +MN908947.3 1312 1337 nCoV-2019_4_RIGHT nCoV-2019_2 +MN908947.3 1242 1264 nCoV-2019_5_LEFT nCoV-2019_1 +MN908947.3 1623 1651 nCoV-2019_5_RIGHT nCoV-2019_1 +MN908947.3 1573 1595 nCoV-2019_6_LEFT nCoV-2019_2 +MN908947.3 1942 1964 nCoV-2019_6_RIGHT nCoV-2019_2 +MN908947.3 1875 1897 nCoV-2019_7_LEFT nCoV-2019_1 +MN908947.3 1868 1890 nCoV-2019_7_LEFT_alt0 nCoV-2019_1 +MN908947.3 2247 2269 nCoV-2019_7_RIGHT nCoV-2019_1 +MN908947.3 2242 2264 nCoV-2019_7_RIGHT_alt5 nCoV-2019_1 +MN908947.3 2181 2205 nCoV-2019_8_LEFT nCoV-2019_2 +MN908947.3 2568 2592 nCoV-2019_8_RIGHT nCoV-2019_2 +MN908947.3 2505 2529 nCoV-2019_9_LEFT nCoV-2019_1 +MN908947.3 2504 2528 nCoV-2019_9_LEFT_alt4 nCoV-2019_1 +MN908947.3 2882 2904 nCoV-2019_9_RIGHT nCoV-2019_1 +MN908947.3 2880 2902 nCoV-2019_9_RIGHT_alt2 nCoV-2019_1 +MN908947.3 2826 2850 nCoV-2019_10_LEFT nCoV-2019_2 +MN908947.3 3183 3210 nCoV-2019_10_RIGHT nCoV-2019_2 +MN908947.3 3144 3166 nCoV-2019_11_LEFT nCoV-2019_1 +MN908947.3 3507 3531 nCoV-2019_11_RIGHT nCoV-2019_1 +MN908947.3 3460 3482 nCoV-2019_12_LEFT nCoV-2019_2 +MN908947.3 3826 3853 nCoV-2019_12_RIGHT nCoV-2019_2 +MN908947.3 3771 3795 nCoV-2019_13_LEFT nCoV-2019_1 +MN908947.3 4142 4164 nCoV-2019_13_RIGHT nCoV-2019_1 +MN908947.3 4054 4077 nCoV-2019_14_LEFT nCoV-2019_2 +MN908947.3 4044 4068 nCoV-2019_14_LEFT_alt4 nCoV-2019_2 +MN908947.3 4428 4450 nCoV-2019_14_RIGHT nCoV-2019_2 +MN908947.3 4402 4424 nCoV-2019_14_RIGHT_alt2 nCoV-2019_2 +MN908947.3 4294 4321 nCoV-2019_15_LEFT nCoV-2019_1 +MN908947.3 4296 4322 nCoV-2019_15_LEFT_alt1 nCoV-2019_1 +MN908947.3 4674 4696 nCoV-2019_15_RIGHT nCoV-2019_1 +MN908947.3 4666 4689 nCoV-2019_15_RIGHT_alt3 nCoV-2019_1 +MN908947.3 4636 4658 nCoV-2019_16_LEFT nCoV-2019_2 +MN908947.3 4995 5017 nCoV-2019_16_RIGHT nCoV-2019_2 +MN908947.3 4939 4966 nCoV-2019_17_LEFT nCoV-2019_1 +MN908947.3 5296 5321 nCoV-2019_17_RIGHT nCoV-2019_1 +MN908947.3 5230 5259 nCoV-2019_18_LEFT nCoV-2019_2 +MN908947.3 5257 5287 nCoV-2019_18_LEFT_alt2 nCoV-2019_2 +MN908947.3 5620 5644 nCoV-2019_18_RIGHT nCoV-2019_2 +MN908947.3 5620 5643 nCoV-2019_18_RIGHT_alt1 nCoV-2019_2 +MN908947.3 5563 5586 nCoV-2019_19_LEFT nCoV-2019_1 +MN908947.3 5932 5957 nCoV-2019_19_RIGHT nCoV-2019_1 +MN908947.3 5867 5894 nCoV-2019_20_LEFT nCoV-2019_2 +MN908947.3 6247 6272 nCoV-2019_20_RIGHT nCoV-2019_2 +MN908947.3 6167 6196 nCoV-2019_21_LEFT nCoV-2019_1 +MN908947.3 6168 6197 nCoV-2019_21_LEFT_alt2 nCoV-2019_1 +MN908947.3 6528 6550 nCoV-2019_21_RIGHT nCoV-2019_1 +MN908947.3 6526 6548 nCoV-2019_21_RIGHT_alt0 nCoV-2019_1 +MN908947.3 6466 6495 nCoV-2019_22_LEFT nCoV-2019_2 +MN908947.3 6846 6873 nCoV-2019_22_RIGHT nCoV-2019_2 +MN908947.3 6718 6745 nCoV-2019_23_LEFT nCoV-2019_1 +MN908947.3 7092 7117 nCoV-2019_23_RIGHT nCoV-2019_1 +MN908947.3 7035 7058 nCoV-2019_24_LEFT nCoV-2019_2 +MN908947.3 7389 7415 nCoV-2019_24_RIGHT nCoV-2019_2 +MN908947.3 7305 7332 nCoV-2019_25_LEFT nCoV-2019_1 +MN908947.3 7671 7694 nCoV-2019_25_RIGHT nCoV-2019_1 +MN908947.3 7626 7651 nCoV-2019_26_LEFT nCoV-2019_2 +MN908947.3 7997 8019 nCoV-2019_26_RIGHT nCoV-2019_2 +MN908947.3 7943 7968 nCoV-2019_27_LEFT nCoV-2019_1 +MN908947.3 8319 8341 nCoV-2019_27_RIGHT nCoV-2019_1 +MN908947.3 8249 8275 nCoV-2019_28_LEFT nCoV-2019_2 +MN908947.3 8635 8661 nCoV-2019_28_RIGHT nCoV-2019_2 +MN908947.3 8595 8619 nCoV-2019_29_LEFT nCoV-2019_1 +MN908947.3 8954 8983 nCoV-2019_29_RIGHT nCoV-2019_1 +MN908947.3 8888 8913 nCoV-2019_30_LEFT nCoV-2019_2 +MN908947.3 9245 9271 nCoV-2019_30_RIGHT nCoV-2019_2 +MN908947.3 9204 9226 nCoV-2019_31_LEFT nCoV-2019_1 +MN908947.3 9557 9585 nCoV-2019_31_RIGHT nCoV-2019_1 +MN908947.3 9477 9502 nCoV-2019_32_LEFT nCoV-2019_2 +MN908947.3 9834 9858 nCoV-2019_32_RIGHT nCoV-2019_2 +MN908947.3 9784 9806 nCoV-2019_33_LEFT nCoV-2019_1 +MN908947.3 10146 10171 nCoV-2019_33_RIGHT nCoV-2019_1 +MN908947.3 10076 10099 nCoV-2019_34_LEFT nCoV-2019_2 +MN908947.3 10437 10459 nCoV-2019_34_RIGHT nCoV-2019_2 +MN908947.3 10362 10384 nCoV-2019_35_LEFT nCoV-2019_1 +MN908947.3 10737 10763 nCoV-2019_35_RIGHT nCoV-2019_1 +MN908947.3 10666 10688 nCoV-2019_36_LEFT nCoV-2019_2 +MN908947.3 11048 11074 nCoV-2019_36_RIGHT nCoV-2019_2 +MN908947.3 10999 11022 nCoV-2019_37_LEFT nCoV-2019_1 +MN908947.3 11372 11394 nCoV-2019_37_RIGHT nCoV-2019_1 +MN908947.3 11306 11331 nCoV-2019_38_LEFT nCoV-2019_2 +MN908947.3 11668 11693 nCoV-2019_38_RIGHT nCoV-2019_2 +MN908947.3 11555 11584 nCoV-2019_39_LEFT nCoV-2019_1 +MN908947.3 11927 11949 nCoV-2019_39_RIGHT nCoV-2019_1 +MN908947.3 11863 11889 nCoV-2019_40_LEFT nCoV-2019_2 +MN908947.3 12234 12256 nCoV-2019_40_RIGHT nCoV-2019_2 +MN908947.3 12110 12133 nCoV-2019_41_LEFT nCoV-2019_1 +MN908947.3 12465 12490 nCoV-2019_41_RIGHT nCoV-2019_1 +MN908947.3 12417 12439 nCoV-2019_42_LEFT nCoV-2019_2 +MN908947.3 12779 12802 nCoV-2019_42_RIGHT nCoV-2019_2 +MN908947.3 12710 12732 nCoV-2019_43_LEFT nCoV-2019_1 +MN908947.3 13074 13096 nCoV-2019_43_RIGHT nCoV-2019_1 +MN908947.3 13005 13027 nCoV-2019_44_LEFT nCoV-2019_2 +MN908947.3 13007 13029 nCoV-2019_44_LEFT_alt3 nCoV-2019_2 +MN908947.3 13378 13400 nCoV-2019_44_RIGHT nCoV-2019_2 +MN908947.3 13363 13385 nCoV-2019_44_RIGHT_alt0 nCoV-2019_2 +MN908947.3 13319 13344 nCoV-2019_45_LEFT nCoV-2019_1 +MN908947.3 13307 13336 nCoV-2019_45_LEFT_alt2 nCoV-2019_1 +MN908947.3 13669 13699 nCoV-2019_45_RIGHT nCoV-2019_1 +MN908947.3 13660 13689 nCoV-2019_45_RIGHT_alt7 nCoV-2019_1 +MN908947.3 13599 13621 nCoV-2019_46_LEFT nCoV-2019_2 +MN908947.3 13602 13625 nCoV-2019_46_LEFT_alt1 nCoV-2019_2 +MN908947.3 13962 13984 nCoV-2019_46_RIGHT nCoV-2019_2 +MN908947.3 13961 13984 nCoV-2019_46_RIGHT_alt2 nCoV-2019_2 +MN908947.3 13918 13946 nCoV-2019_47_LEFT nCoV-2019_1 +MN908947.3 14271 14299 nCoV-2019_47_RIGHT nCoV-2019_1 +MN908947.3 14207 14232 nCoV-2019_48_LEFT nCoV-2019_2 +MN908947.3 14579 14601 nCoV-2019_48_RIGHT nCoV-2019_2 +MN908947.3 14545 14570 nCoV-2019_49_LEFT nCoV-2019_1 +MN908947.3 14898 14926 nCoV-2019_49_RIGHT nCoV-2019_1 +MN908947.3 14865 14895 nCoV-2019_50_LEFT nCoV-2019_2 +MN908947.3 15224 15246 nCoV-2019_50_RIGHT nCoV-2019_2 +MN908947.3 15171 15193 nCoV-2019_51_LEFT nCoV-2019_1 +MN908947.3 15538 15560 nCoV-2019_51_RIGHT nCoV-2019_1 +MN908947.3 15481 15503 nCoV-2019_52_LEFT nCoV-2019_2 +MN908947.3 15861 15886 nCoV-2019_52_RIGHT nCoV-2019_2 +MN908947.3 15827 15851 nCoV-2019_53_LEFT nCoV-2019_1 +MN908947.3 16186 16209 nCoV-2019_53_RIGHT nCoV-2019_1 +MN908947.3 16118 16144 nCoV-2019_54_LEFT nCoV-2019_2 +MN908947.3 16485 16510 nCoV-2019_54_RIGHT nCoV-2019_2 +MN908947.3 16416 16444 nCoV-2019_55_LEFT nCoV-2019_1 +MN908947.3 16804 16833 nCoV-2019_55_RIGHT nCoV-2019_1 +MN908947.3 16748 16770 nCoV-2019_56_LEFT nCoV-2019_2 +MN908947.3 17130 17152 nCoV-2019_56_RIGHT nCoV-2019_2 +MN908947.3 17065 17087 nCoV-2019_57_LEFT nCoV-2019_1 +MN908947.3 17430 17452 nCoV-2019_57_RIGHT nCoV-2019_1 +MN908947.3 17381 17406 nCoV-2019_58_LEFT nCoV-2019_2 +MN908947.3 17738 17761 nCoV-2019_58_RIGHT nCoV-2019_2 +MN908947.3 17674 17697 nCoV-2019_59_LEFT nCoV-2019_1 +MN908947.3 18036 18062 nCoV-2019_59_RIGHT nCoV-2019_1 +MN908947.3 17966 17993 nCoV-2019_60_LEFT nCoV-2019_2 +MN908947.3 18324 18348 nCoV-2019_60_RIGHT nCoV-2019_2 +MN908947.3 18253 18275 nCoV-2019_61_LEFT nCoV-2019_1 +MN908947.3 18650 18672 nCoV-2019_61_RIGHT nCoV-2019_1 +MN908947.3 18596 18618 nCoV-2019_62_LEFT nCoV-2019_2 +MN908947.3 18957 18979 nCoV-2019_62_RIGHT nCoV-2019_2 +MN908947.3 18896 18918 nCoV-2019_63_LEFT nCoV-2019_1 +MN908947.3 19275 19297 nCoV-2019_63_RIGHT nCoV-2019_1 +MN908947.3 19204 19232 nCoV-2019_64_LEFT nCoV-2019_2 +MN908947.3 19591 19616 nCoV-2019_64_RIGHT nCoV-2019_2 +MN908947.3 19548 19570 nCoV-2019_65_LEFT nCoV-2019_1 +MN908947.3 19911 19939 nCoV-2019_65_RIGHT nCoV-2019_1 +MN908947.3 19844 19866 nCoV-2019_66_LEFT nCoV-2019_2 +MN908947.3 20231 20255 nCoV-2019_66_RIGHT nCoV-2019_2 +MN908947.3 20172 20200 nCoV-2019_67_LEFT nCoV-2019_1 +MN908947.3 20542 20572 nCoV-2019_67_RIGHT nCoV-2019_1 +MN908947.3 20472 20496 nCoV-2019_68_LEFT nCoV-2019_2 +MN908947.3 20867 20890 nCoV-2019_68_RIGHT nCoV-2019_2 +MN908947.3 20786 20813 nCoV-2019_69_LEFT nCoV-2019_1 +MN908947.3 21146 21169 nCoV-2019_69_RIGHT nCoV-2019_1 +MN908947.3 21075 21104 nCoV-2019_70_LEFT nCoV-2019_2 +MN908947.3 21427 21455 nCoV-2019_70_RIGHT nCoV-2019_2 +MN908947.3 21357 21386 nCoV-2019_71_LEFT nCoV-2019_1 +MN908947.3 21716 21743 nCoV-2019_71_RIGHT nCoV-2019_1 +MN908947.3 21658 21682 nCoV-2019_72_LEFT nCoV-2019_2 +MN908947.3 22013 22038 nCoV-2019_72_RIGHT nCoV-2019_2 +MN908947.3 21961 21990 nCoV-2019_73_LEFT nCoV-2019_1 +MN908947.3 22324 22346 nCoV-2019_73_RIGHT nCoV-2019_1 +MN908947.3 22262 22290 nCoV-2019_74_LEFT nCoV-2019_2 +MN908947.3 22626 22650 nCoV-2019_74_RIGHT nCoV-2019_2 +MN908947.3 22516 22542 nCoV-2019_75_LEFT nCoV-2019_1 +MN908947.3 22877 22903 nCoV-2019_75_RIGHT nCoV-2019_1 +MN908947.3 22797 22819 nCoV-2019_76_LEFT nCoV-2019_2 +MN908947.3 22798 22821 nCoV-2019_76_LEFT_alt3 nCoV-2019_2 +MN908947.3 23192 23214 nCoV-2019_76_RIGHT nCoV-2019_2 +MN908947.3 23189 23212 nCoV-2019_76_RIGHT_alt0 nCoV-2019_2 +MN908947.3 23122 23144 nCoV-2019_77_LEFT nCoV-2019_1 +MN908947.3 23500 23522 nCoV-2019_77_RIGHT nCoV-2019_1 +MN908947.3 23443 23466 nCoV-2019_78_LEFT nCoV-2019_2 +MN908947.3 23822 23847 nCoV-2019_78_RIGHT nCoV-2019_2 +MN908947.3 23789 23812 nCoV-2019_79_LEFT nCoV-2019_1 +MN908947.3 24145 24169 nCoV-2019_79_RIGHT nCoV-2019_1 +MN908947.3 24078 24100 nCoV-2019_80_LEFT nCoV-2019_2 +MN908947.3 24443 24467 nCoV-2019_80_RIGHT nCoV-2019_2 +MN908947.3 24391 24416 nCoV-2019_81_LEFT nCoV-2019_1 +MN908947.3 24765 24789 nCoV-2019_81_RIGHT nCoV-2019_1 +MN908947.3 24696 24721 nCoV-2019_82_LEFT nCoV-2019_2 +MN908947.3 25052 25076 nCoV-2019_82_RIGHT nCoV-2019_2 +MN908947.3 24978 25003 nCoV-2019_83_LEFT nCoV-2019_1 +MN908947.3 25347 25369 nCoV-2019_83_RIGHT nCoV-2019_1 +MN908947.3 25279 25301 nCoV-2019_84_LEFT nCoV-2019_2 +MN908947.3 25646 25673 nCoV-2019_84_RIGHT nCoV-2019_2 +MN908947.3 25601 25623 nCoV-2019_85_LEFT nCoV-2019_1 +MN908947.3 25969 25994 nCoV-2019_85_RIGHT nCoV-2019_1 +MN908947.3 25902 25924 nCoV-2019_86_LEFT nCoV-2019_2 +MN908947.3 26290 26315 nCoV-2019_86_RIGHT nCoV-2019_2 +MN908947.3 26197 26219 nCoV-2019_87_LEFT nCoV-2019_1 +MN908947.3 26566 26590 nCoV-2019_87_RIGHT nCoV-2019_1 +MN908947.3 26520 26542 nCoV-2019_88_LEFT nCoV-2019_2 +MN908947.3 26890 26913 nCoV-2019_88_RIGHT nCoV-2019_2 +MN908947.3 26835 26857 nCoV-2019_89_LEFT nCoV-2019_1 +MN908947.3 26838 26860 nCoV-2019_89_LEFT_alt2 nCoV-2019_1 +MN908947.3 27202 27227 nCoV-2019_89_RIGHT nCoV-2019_1 +MN908947.3 27190 27215 nCoV-2019_89_RIGHT_alt4 nCoV-2019_1 +MN908947.3 27141 27164 nCoV-2019_90_LEFT nCoV-2019_2 +MN908947.3 27511 27533 nCoV-2019_90_RIGHT nCoV-2019_2 +MN908947.3 27446 27471 nCoV-2019_91_LEFT nCoV-2019_1 +MN908947.3 27825 27854 nCoV-2019_91_RIGHT nCoV-2019_1 +MN908947.3 27784 27808 nCoV-2019_92_LEFT nCoV-2019_2 +MN908947.3 28145 28172 nCoV-2019_92_RIGHT nCoV-2019_2 +MN908947.3 28081 28104 nCoV-2019_93_LEFT nCoV-2019_1 +MN908947.3 28442 28464 nCoV-2019_93_RIGHT nCoV-2019_1 +MN908947.3 28394 28416 nCoV-2019_94_LEFT nCoV-2019_2 +MN908947.3 28756 28779 nCoV-2019_94_RIGHT nCoV-2019_2 +MN908947.3 28677 28699 nCoV-2019_95_LEFT nCoV-2019_1 +MN908947.3 29041 29063 nCoV-2019_95_RIGHT nCoV-2019_1 +MN908947.3 28985 29007 nCoV-2019_96_LEFT nCoV-2019_2 +MN908947.3 29356 29378 nCoV-2019_96_RIGHT nCoV-2019_2 +MN908947.3 29288 29316 nCoV-2019_97_LEFT nCoV-2019_1 +MN908947.3 29665 29693 nCoV-2019_97_RIGHT nCoV-2019_1 +MN908947.3 29486 29510 nCoV-2019_98_LEFT nCoV-2019_2 +MN908947.3 29836 29866 nCoV-2019_98_RIGHT nCoV-2019_2 diff -r 000000000000 -r 7a82006f7c05 test-data/primer_scheme_bedfiles.loc --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/primer_scheme_bedfiles.loc Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,6 @@ +# Tab separated with three columns: +# - value (Galaxy records this in the Galaxy DB) +# - name (Galaxy shows this in the UI) +# - path (the primer scheme bedfile) +# +test_entry "Test Database" ${__HERE__}/nCoV-2019.scheme.V1.bed diff -r 000000000000 -r 7a82006f7c05 test-data/test.fastq --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/test.fastq Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,40 @@ +@8db09f2a-de97-4ebd-80ac-fdd69d356cad +TGGTCCATGTAACTACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTTTAAAATCTGTGTGGCTGTCCTCCGGCTGCATGCTTAGTGCCACTCACGCAGTATAATTAATATTAATTACTGTCGTTGACAGGACCTTTTTGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTTTGTCGATCATCAACATCTAGGTTTTGTCCGGGTGTGACCGAAAGGTAGATGGAGAGCCTTGTCCCTGGA ++ +%&%$&$$##$$((%'(:7=@8,>@@C=DB;;>EG;:44456<7CC=<4:)21'-,,06::93;?@?9:=5:3<>?@B?+,0053%(&$$)566)*-)7<9//(&.=0.))*)44;CA@>94--%%21-.77;?=@3*19-((?6$/0/1322(#3572:;????@AACFB@LGCADNBQK=?;<@>A@B<.,0%5676830370128=75A?C;942(+--.-,*423/<=<>=42))&# +@9518353b-8dcc-460f-9801-2be35ffc6a19 +AAGCATGCTTCGTTCAGTTACGTGGTAACACCAACCAACTTTCGATCTCTTGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTGGCTCTCTCGGCTGCAATAGTGCACTCACGTGTAATTAATAACTAATTACTGTCGTTTGACAGGACCTGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCCATCTAGGTTTTGTCGGGTGTGACCGAAGGTAAGATGGAGAGCCTTGTCCCTGGTTTCAACGAGGAAAACACGTCCACTCAGTTTGCCTGTTTTACAGGTTCGCGACGATGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGGCACGTCAGCATCTTAAAGATGGTAATACGTAACTTAAGCATGCTTCGTTCAGTTACGTGGTAACACCAACCAACTTTCGATCTCTTGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTGGCTCTCTCGGCTGCAATAGTGCACTCACGTGTAATTAATAACTAATTACTGTCGTTTGACAGGACCTGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCCATCTAGGTTTTGTCGGGTGTGACCGAAGGTAAGATGGAGAGCCTTGTCCCTGGTTTCAACGAGGAAAACACGTCCACTCAGTTTGCCTGTTTTACAGGTTCGCGACGATGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGGCACGTCAGCATCTTAAAGATGGTAATACGTAACTTAAGCATGCTTCGTTCAGTTACGTGGTAACACCAACCAACTTTCGATCTCTTGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTGGCTCTCTCGGCTGCAATAGTGCACTCACGTGTAATTAATAACTAATTACTGTCGTTTGACAGGACCTGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCCATCTAGGTTTTGTCGGGTGTGACCGAAGGTAAGATGGAGAGCCTTGTCCCTGGTTTCAACGAGGAAAACACGTCCACTCAGTTTGCCTGTTTTACAGGTTCGCGACGATGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGGCACGTCAGCATCTTAAAGATGGTAATACGTAACTTAAGCATGCTTCGTTCAGTTACGTGGTAACACCAACCAACTTTCGATCTCTTGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTGGCTCTCTCGGCTGCAATAGTGCACTCACGTGTAATTAATAACTAATTACTGTCGTTTGACAGGACCTGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCCATCTAGGTTTTGTCGGGTGTGACCGAAGGTAAGATGGAGAGCCTTGTCCCTGGTTTCAACGAGGAAAACACGTCCACTCAGTTTGCCTGTTTTACAGGTTCGCGACGATGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGGCACGTCAGCATCTTAAAGATGGTAATACGTAACTT ++ +,,%+),+78;:(=FBFGB8C>19:;=DMM>KGEA:85-0+))&$$$)*%-(0''&$&%$%:@800<>;$%%)$1666?@?DM@@B8/+#*-.83009<8%%$522;A>:;B=;@==BDAAD@633;9880)19@BE2QLQA?>@D>CFGA2,-?:896::9***67616>8;FJD0*662>@@@BA?B;799?:;7;9001-03501252:;=<=86@G@75258F6%0755/*/*)*%$$&/+.-033=@?AGD=1,--0<<30,*-%()*+.3:7/00341/,+/0-%//).3696.-57<94:><9?==94>3)?::9;364&;>@>=:77;FBFGB8C>19:;=DMM>KGEA:85-0+))&$$$)*%-(0''&$&%$%:@800<>;$%%)$1666?@?DM@@B8/+#*-.83009<8%%$522;A>:;B=;@==BDAAD@633;9880)19@BE2QLQA?>@D>CFGA2,-?:896::9***67616>8;FJD0*662>@@@BA?B;799?:;7;9001-03501252:;=<=86@G@75258F6%0755/*/*)*%$$&/+.-033=@?AGD=1,--0<<30,*-%()*+.3:7/00341/,+/0-%//).3696.-57<94:><9?==94>3)?::9;364&;>@>=:77;FBFGB8C>19:;=DMM>KGEA:85-0+))&$$$)*%-(0''&$&%$%:@800<>;$%%)$1666?@?DM@@B8/+#*-.83009<8%%$522;A>:;B=;@==BDAAD@633;9880)19@BE2QLQA?>@D>CFGA2,-?:896::9***67616>8;FJD0*662>@@@BA?B;799?:;7;9001-03501252:;=<=86@G@75258F6%0755/*/*)*%$$&/+.-033=@?AGD=1,--0<<30,*-%()*+.3:7/00341/,+/0-%//).3696.-57<94:><9?==94>3)?::9;364&;>@>=:77;FBFGB8C>19:;=DMM>KGEA:85-0+))&$$$)*%-(0''&$&%$%:@800<>;$%%)$1666?@?DM@@B8/+#*-.83009<8%%$522;A>:;B=;@==BDAAD@633;9880)19@BE2QLQA?>@D>CFGA2,-?:896::9***67616>8;FJD0*662>@@@BA?B;799?:;7;9001-03501252:;=<=86@G@75258F6%0755/*/*)*%$$&/+.-033=@?AGD=1,--0<<30,*-%()*+.3:7/00341/,+/0-%//).3696.-57<94:><9?==94>3)?::9;364&;>@>=:77;>A2/0//1124664;67:>6014*8315---&'%%%%%%.+$%%)*%'''(*.%''37A8I<87*.,/552)$&%%$&=AB>9200402)&%'&)454?;>--8+'),)/8B/0C:=HB1((>&+030DE,6'01**))'+&&'''.0,020//4.&0(*7?A0/.023(2.42-+.(%=1.;:A3'A:)976;.LLP*%(,%2@=61.0&,,4/?D=&&&)(...$$,7)-,'<FD=84:3(2(5/>BB0)B)(4?;*-781/-&'$###*+3++)1>B(&&))&,,-.-(00&2?=;>HE@C:/1.&(9E@70%%--%%%%&%./8;:993&.')4544)%(')*8?B?@F=898&//;1$.98:1..,*==><6B87:8<:<++)+,,))%,,,+%$##&832::>1@ED.1>?@>EC3'%%$&1.-)&&',+,---**:2+(0+,%&#'()*-',002>=A/0<:>2%%-)*22269?C??.<=<>>A<55+&'' +@80de96c0-f65f-45b6-9962-0646f207ffb2 +GATCACTTCGTTCCGGTTACGTAACACTACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTCTAAGCAGACTTTAAAATCGCAACATCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAATAATTACTGTCGTTGACGGACTGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAACACATCTAGGTTTTGTCGGGTGGCAATGAAAGGTAGATGGAGAGCCTTGTCCCTGGTTTCAACGAGAAAACACGTCAACTCAGTTTGCCTGTTTACGGTTCGCGACGTACTCGTAAATGCGGTAACTGGGAACTCGTGGAGGGTCTTATCAGAGGCACGTCAACATCTCTAAAGATGAGCAATACGTAATGCTTGA ++ +$#'%#$/05>=??=:BA;IA2---'$6''()''-&)%-.%&%%1/776AA:4.2$"$%%%-:,.1:@@A>=9900&&*09=50/6:<8>744;>;7863510/3+068481;>?AE8GG=7'&,..(),378899@?;=859ACCB;7334=>9,#%,@@=?TQMFD@CD==:G:=88<=;221?4/<9)&.(:79&%0;:;'=6GA3DGC@<:8((+,-&%'(+8)*)*-''((153+-,+.,)(./588''&7;=:>>=3//+%$"##$# +@197e8890-1cb3-4c52-a783-5ef3ce80953a +CTGCTTCGTTCAGTTACGTATTGCACAAACCAATAACTTTTTCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTGGCTGTCACTCGACTGCATGCTTAGTGCACTCACGCGGTATAATTAATAACTAATTACTGTCGTTGACAGGACACGGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAACATCTAGGTTTGTCAGGTGTGACCGAAAGGTAAAGATAGAGCCTTGTCCCTGGTTTCAACGAGAAAACACACGATCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGATATCATTACGTGGCATTGGAGACTCCGTGGAGGAGGTCTTATCAGAGGCGTCAACATCTTAAAGATGGTAATACGTAACTTG ++ +#$$""&+0.?<<;9'%$$##&$$555:2''+99=?9636@A=E586?;<=CFJA@8''*CD?A?<<:68@5:?F526AAHFAC-;ACEHDCA9=B@@EDA>A<=AB=@664/68:363/8,,267339DI@:CA8?9EA>;)$$$4*45237>B@-?79BEFCG<5892%*+)$%'$%4$%::7;;@/?AE;@CDF@EFH=;;<3><69769444)*((,''+253>63119<=<;8??BJG@C@>4%%-9><=G:=77),$%1'*7:<5640)++58463..',-+(.53341##$$ +@74fdf93b-4411-4aba-8346-7c443da2eead +GTTGTACTTCGTTCAGTTACGTGACAACACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTTAAAATCTGTCGTGCAGCTGTCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAATAATTACTGTCGTTGACAGGACTGAGTAACTCGTCTATCTTCTGCAAGGCATACGGTTTTCGTCCGTGTTGGCAATCCATCATCGGTTTTTTGTCGGGTGTGACCGAAAGGTAGATGGAGAGCCTTGTCCCTACTGGTTTCTTGAAAACACACGTCACTCGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTATTGGCTTTGGAGGCTGTGGAGGATATATCAGAGGCGTCAACATCTTAAAGATGAGCAATACGTAGCCT ++ +#,-.00//9CDH?<16)*%%&#&#&#$#%(''-4457227??:;=7>;63;:::0,1,.02:;84A>5889>>@<1&(()57355>BA7>/&&>=BA;>.>;/,&&:6/+)+(%/1/3470'9-C?C>;*('&&&'&&#&&*%'&,/.*-))*%'%(,%$*%)##''(%$*0%(,139:<0)405C>?BD@BA995,1.((+23311,08,-+/2435/&&%('*%&,&$$&--/,,''$'+).%$'&'(7C/;:;:CBA+%&*/9CE>4801')+**./**%%'1399<635/-$$&%-//&&*%$$''2738018*->A<.:;:75534334556979589:3-*%#$# +@8fbace70-be6b-4be2-b03c-9265c1693576 +ATATCGCCGTTCAGTTACGTGTACACACCAACCAGCACCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTCCCAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCCTCACGCGGTATAATTAATAATAATTACTGTCGTTGACAGGACACGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCGGCCGATCATCAACACACATCTAGGTTTTGTCCGGGTGCTGACCCAGGTAAGATGGAAGCCTTGTCCCACCTAGTTTCAACGAGAAAACACACGTCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTGGAGACTCCAGTGGAGGTCTTATCAGGAGGCACGTCAACATCACTAAAGATGAGCAATACATGTG ++ +##$%%&'*-/,<()13+00'&*'%$$$'(),562%%%%,00660,$**)../0;,.>?ACB3576///2))+&'&'+-+@,015(),@;5;<@@<94/&&&(*+*9==73;5*00'3&96@1.0;BLSN>%%@'(5;9$@JCBB&&'=@DDDJDD=;(.568895562-13*%:>EB:;<55467,2-&%##&*493.<;?-:7B;2>?=9><7*%%$9:@35657232;5>B@05187***',(-4:669:5')458.-??EGD467(+'(&-++-.7?:,::93%#0/0,04+++6=>999(%%$%# +@2c03f5fc-9a7b-479a-8d6c-a5bb76a79ed2 +AGTGTGCTTCGTTCAGTTACGTATTGCTACCAACCAATAAACTTTCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTTGATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACTCACATGGTAGTATAATTAATAACTAGTACTGTCGTTGACAGGACACGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAGCTTTATCTAGGTTTTGTCCGGGTGTGACCGAAGGTAAGATGGAGAGCCTTGTCCCTGTTTTCAACGAGAAAACACGTCAACTCAGTTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGAGCACGTCAACATCTTAAAGATAGGCAATACGTAACTGA ++ +)&%&+,6==>:I7D+@/(9;;18812;0,.-(@HH?BEB?@DBC?0(((=;B?>?AA@BFPI>A53347<;1))9<@?DACF:5;.-((+061B7DB&&?9>D?CFGJADFDF=EEOG;<7787?7B=>:?>=>AC:4>761..86/<.9;;:-9:@C>$6,23<4AEFGG@?F>@>FEC>C@IF)+079>@?A1+:0,',***78@B1::53(+<<<7*$$$;=CDBA=000,)*$$ +@78cf30ba-8f84-45cd-b9b6-0bc6f3500787 +AAACGTACTTCGTTCAGTTACGTATTGCTAACCAACCAACTTTCGATCTGTAGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACTCCGCAGTATAATTAATAACTAATTACTGTCGTTGACAGGACACGAGTAATATTATCTTCTTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAGCACATCTAGGTTTGTGATTGTGACCGAAGGTAAGATGGAGAGCCTTGTCCCTAGTTTCAACGAGAAAACACACGTCAACTCAGTTTGCCTCTTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGAGGCACGTCAACATCTTAAAGATGAGCAATACGTAACTGA ++ +(($%%$#$*/39A9C4:=:''$''&'27,53-/%((,-,$$-3732/12$*120*((6@BFFB*MIE1113667+6;@@;;;-$,6077831;13;7)'%+*,-5&#&--:1+/**9;/*435BDDFA=>@@AG;4:>83:>>C@<--8<8%,4496?866>;;A@:<9:<5/<<$8@(;4>1/.8,>,$%$%)+-=>?C??C>8DF=>?=:226&%$*0026<3476,718:66/,*.&5>;A=<1:38-&''+&'*==89878CFE7//3-4*56>?9*5598..0101(%(*.;9;9410.0*%$2AB:;:CC@>ABFF?D<;;8001ACC5665.))($$## diff -r 000000000000 -r 7a82006f7c05 tool-data/all_fasta.loc.sample --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool-data/all_fasta.loc.sample Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,18 @@ +#This file lists the locations and dbkeys of all the fasta files +#under the "genome" directory (a directory that contains a directory +#for each build). The script extract_fasta.py will generate the file +#all_fasta.loc. This file has the format (white space characters are +#TAB characters): +# +# +# +#So, all_fasta.loc could look something like this: +# +#apiMel3 apiMel3 Honeybee (Apis mellifera): apiMel3 /path/to/genome/apiMel3/apiMel3.fa +#hg19canon hg19 Human (Homo sapiens): hg19 Canonical /path/to/genome/hg19/hg19canon.fa +#hg19full hg19 Human (Homo sapiens): hg19 Full /path/to/genome/hg19/hg19full.fa +# +#Your all_fasta.loc file should contain an entry for each individual +#fasta file. So there will be multiple fasta files for each build, +#such as with hg19 above. +# diff -r 000000000000 -r 7a82006f7c05 tool-data/primer_scheme_bedfiles.loc.sample --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool-data/primer_scheme_bedfiles.loc.sample Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,8 @@ +# this is a tab separated file describing the location of primer schemes used for amplicon +# sequencing (e.g. using the ARTIC SARS-CoV-2 protocol) +# +# the columns are: +# value description path +# +# for example +# SARS-CoV-2-ARTICv1 SARS-CoV-2 ARTIC v1 primers /data/galaxy/tool_data/artic_primers/SARS-CoV-2-ARTICv1.bed diff -r 000000000000 -r 7a82006f7c05 tool_data_table_conf.xml.sample --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_data_table_conf.xml.sample Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,13 @@ + + + + + value, description, path + +
+ + + value, dbkey, name, path + +
+
diff -r 000000000000 -r 7a82006f7c05 tool_data_table_conf.xml.test --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_data_table_conf.xml.test Fri Aug 27 20:34:52 2021 +0000 @@ -0,0 +1,12 @@ + + + + + value, name, path + +
+ + value, dbkey, name, path + +
+