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planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/bigscape/ commit 1c7a35c3aabb33682b263cb3a8dbeaf605469c23
author | iuc |
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date | Sun, 25 Feb 2024 10:51:27 +0000 |
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LOCUS NW_022985549 47951 bp DNA linear CON 21-APR-2020 DEFINITION Pseudovirgaria hyperparasitica strain CBS 121739 unplaced genomic scaffold EJ05scaffold_1, whole genome shotgun sequence. ACCESSION NW_022985549 VERSION NW_022985549.1 KEYWORDS . SOURCE Pseudovirgaria hyperparasitica ORGANISM Pseudovirgaria hyperparasitica Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes; Dothideomycetes incertae sedis; Acrospermales; Acrospermaceae; Pseudovirgaria. COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to ML996565. URL -- http://genome.jgi.doe.gov/Psehy1 JGI Project ID: 1032442 The DNA was provided by Pedro Crous (p.crous@westerdijkinstitute.nl) The strain is available from CBS collection Contacts: Pedro Crous (p.crous@westerdijkinstitute.nl) Assembly and annotation done by JGI. The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. It is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2023-11-19 23:27:26 NOTE: This is a single region extracted from a larger record! Orig. start :: 1832405 Orig. end :: 1880356 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..47951 /aStool="rule-based-clusters" /category="PKS" /contig_edge="False" /core_location="[20000:27951]" /cutoff="20000" /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))" /neighbourhood="20000" /product="T1PKS" /protocluster_number="1" /tool="antismash" proto_core 20001..27951 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))" /neighbourhood="20000" /product="T1PKS" /protocluster_number="1" cand_cluster 1..47951 /SMILES="C([*])C(-O)(C)" /candidate_cluster_number="1" /contig_edge="False" /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))" /kind="single" /product="T1PKS" /protoclusters="1" /tool="antismash" region 1..47951 /candidate_cluster_numbers="1" /contig_edge="False" /product="T1PKS" /region_number="5" /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))" /tool="antismash" gene complement(<1483..>2344) /db_xref="GeneID:54487359" /locus_tag="EJ05DRAFT_495884" mRNA complement(join(<1483..1517,1573..>2344)) /db_xref="GeneID:54487359" /locus_tag="EJ05DRAFT_495884" /product="3-oxoacyl-reductase" /transcript_id="XM_033746305.1" CDS complement(join(1483..1517,1573..2344)) /NRPS_PKS="Domain: PKS_KR (10-194). E-value: 1.3e-10. Score: 33.3. Matches aSDomain: nrpspksdomains_EJ05DRAFT_495884_PKS_KR.1" /codon_start=1 /db_xref="GeneID:54487359" /db_xref="InterPro:IPR002198" /db_xref="JGIDB:Psehy1_495884" /gene_functions="biosynthetic-additional (smcogs) SMCOG1001:short-chain dehydrogenase/reductase SDR (Score: 168.8; E-value: 2.5e-51)" /gene_kind="biosynthetic-additional" /locus_tag="EJ05DRAFT_495884" /product="3-oxoacyl-reductase" /protein_id="XP_033605494.1" /transl_table=1 /translation="MSTPPPFTGKTIAITGAASGIGLATAHYLARNGASLSLADISASA LASAASTLSLTHSAPLIYRVVDVRDASAVNEWIDATLEKFGALHGAVNAAGTNGGNPPA TPIWDVDDALYARITGVNVTGVWNCMRAQLRAMGCGRETEVGMPGEGKGMEVAGQRGCV VNVASIAGVAGRAGSAAYAASKHAVVGMSKSAAMEAGAWGVRVNVVAPGYVDTPMMVYI RDEVERLSLKRVGKAEEIAGLIGWVLGGEGSAYVTGEVYGSMGGWF" PFAM_domain complement(1670..2317) /aSDomain="adh_short" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00106.28" /description="short chain dehydrogenase" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_495884_0085" /evalue="2.00E-42" /label="EJ05DRAFT_495884" /locus_tag="EJ05DRAFT_495884" /protein_end="225" /protein_start="9" /score="145.0" /tool="antismash" /translation="KTIAITGAASGIGLATAHYLARNGASLSLADISASALASAASTLS LTHSAPLIYRVVDVRDASAVNEWIDATLEKFGALHGAVNAAGTNGGNPPATPIWDVDDA LYARITGVNVTGVWNCMRAQLRAMGCGRETEVGMPGEGKGMEVAGQRGCVVNVASIAGV AGRAGSAAYAASKHAVVGMSKSAAMEAGAWGVRVNVVAPGYVDTPMMVYIRDE" aSDomain complement(1763..2314) /aSDomain="PKS_KR" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EJ05DRAFT_495884_PKS_KR.1" /evalue="1.30E-10" /label="EJ05DRAFT_495884_PKS_KR.1" /locus_tag="EJ05DRAFT_495884" /protein_end="194" /protein_start="10" /score="33.3" /specificity="KR activity: inactive" /specificity="KR stereochemistry: C2" /tool="antismash" /translation="TIAITGAASGIGLATAHYLARNGASLSLADISASALASAASTLSL THSAPLIYRVVDVRDASAVNEWIDATLEKFGALHGAVNAAGTNGGNPPATPIWDVDDAL YARITGVNVTGVWNCMRAQLRAMGCGRETEVGMPGEGKGMEVAGQRGCVVNVASIAGVA GRAGSAAYAASKHAVVGMSKS" CDS_motif complement(2243..2305) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_495884_0001" /evalue="5.40E-06" /label="PKSI-KR_m1" /locus_tag="EJ05DRAFT_495884" /protein_end="34" /protein_start="13" /score="19.1" /tool="antismash" /translation="ITGAASGIGLATAHYLARNGA" gene complement(2755..5262) /db_xref="GeneID:54481099" /locus_tag="EJ05DRAFT_24020" mRNA complement(2755..5262) /db_xref="GeneID:54481099" /locus_tag="EJ05DRAFT_24020" /product="uncharacterized protein" /transcript_id="XM_033740045.1" CDS complement(2991..4940) /codon_start=1 /db_xref="GeneID:54481099" /db_xref="JGIDB:Psehy1_24020" /locus_tag="EJ05DRAFT_24020" /note="expressed protein" /product="uncharacterized protein" /protein_id="XP_033605495.1" /transl_table=1 /translation="MTTMFASMPWRSTRERPTSTRLTASPSEAPDKGLHEALDLRDLNN ALKALVDIFPDVQPEVFREMLMAFGDESRLQVVTEAMLKNKSKFVAGRWRSSINGEDEQ KEEGTPSRKYKYKSTSAKGTREAPLVLEDQFRSKSYRDAVKAQLYQEFKNLSRSTINAV LAEHNYSYTHSRPTLLGLNTQSWRYSLTKLFTRKKSPGVEDHPLLEWHRESRAGGPTTP RLISTNNFELDKELYEQLIEPIIATQMAEQVANDHELAEKLNEEQAEELGEMYDCECCF TSSTIEQLSACNEDGHFICFRCIRHTVDEALYGQGWSRSIDIENSSLRCMAVSNAECRG RLTSQSLEIALRSSGKEGTDSLRKLNERFTTEALIKSQIPLIQCPFCPYAEVDTIALSK PPLALSLRPQPVIVSISLFGLANLLSTILRFVFLFIFFFVNLNYLLLPTPLPLLSPVTA SLTRIARRRHGLRFTCGSRACARSSCLSCSAEWPPNTLHTCHSSALTSLRTTVERAMAD AVKRTCPQCHTNFVKESGCNKMRCTCGYTMCYVCRDKIGTEGYAHFCQHFRRTPGANCV QCDRCDLYRTEDEEALRKRAGEEAEKNWRENNALVEDDIARQGLAQLRGGGQMVLRRAA LESLLDRFLDAVIA" gene <6631..>7539 /db_xref="GeneID:54487360" /locus_tag="EJ05DRAFT_495886" mRNA <6631..>7539 /db_xref="GeneID:54487360" /locus_tag="EJ05DRAFT_495886" /product="uncharacterized protein" /transcript_id="XM_033746306.1" CDS 6631..7539 /codon_start=1 /db_xref="GeneID:54487360" /db_xref="JGIDB:Psehy1_495886" /locus_tag="EJ05DRAFT_495886" /note="expressed protein" /product="uncharacterized protein" /protein_id="XP_033605496.1" /transl_table=1 /translation="MVVRQRNKRSKGEDVPSPKANTQLKQDLPTVLSIPDVAGYDINDL MMPLPPLDMDIVCIDDGDTYSWNNGPGLTYNGDDDSMTQESSGTGPTLSQDESKDTLTE QLMKLSQRATRATRELECGEIVLPLTVNSPVVNEAFETANALVRIINSMPLTDSTYESS LLSRDSSQQQLPTFLALAAYQYVLGLFRAICGSIKCSSGSIAQGIELQQQTLHGAGSCS AQFIMVLQLIMHLLNRIGRSLRTGSRRNSDQHELGGGEVGSLQGVVDSAQVMLRSMTDE HVKLGGVIQDLQAGIEEGVHM" CDS complement(join(9317..9328,9467..9959,10055..10596)) /NRPS_PKS="Domain: PKS_ER (24-229). E-value: 2.3e-24. Score: 77.9. Matches aSDomain: nrpspksdomains_EJ05DRAFT_534469_PKS_ER.1" /codon_start=1 /db_xref="GeneID:54490241" /db_xref="InterPro:IPR013149" /db_xref="InterPro:IPR013154" /db_xref="JGIDB:Psehy1_534469" /gene_functions="biosynthetic-additional (rule-based-clusters) ADH_N" /gene_functions="biosynthetic-additional (rule-based-clusters) ADH_zinc_N" /gene_functions="biosynthetic-additional (smcogs) SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase (Score: 174.7; E-value: 4.4e-53)" /gene_kind="biosynthetic-additional" /locus_tag="EJ05DRAFT_534469" /product="GroES-like protein" /protein_id="XP_033605497.1" /sec_met_domain="ADH_N (E-value: 1e-05, bitscore: 21.6, seeds: 66, tool: rule-based-clusters)" /sec_met_domain="ADH_zinc_N (E-value: 5.1e-12, bitscore: 42.1, seeds: 86, tool: rule-based-clusters)" /transl_table=1 /translation="MKPSTAMKALVGDEAGGYRLADDIEIPTPKPGMILCQVRSVALSP YDAKIVDYSNTPGAIGGCDFAGIVASVGEGVTRFKKGDRILAVTFGLNASDKTAGAFAE YALATEDLSCHVPENISFEQASSMGLGIATAGLALFQAPGLALELPRPKSAEDTPSFVL VSGGATGTGTMATQLLKIAGYTPIVTCSPANNAICESFGAAACFDYRSSTCGADIREYT ANSLVSVFDCVTDASTMRMCYEAIGSSGGRYVALEAVSPIVKYTRRDVRADWLMAPTIM GTPVEIPGTYGRPSTPEHRAFGLNLFLLADKLLNEGRIKNHPLEIRAGGLASIPTYVND LRVGNNGS" gene complement(<9317..10689) /db_xref="GeneID:54490241" /locus_tag="EJ05DRAFT_534469" mRNA complement(join(<9317..9328,9467..9959,10055..10689)) /db_xref="GeneID:54490241" /locus_tag="EJ05DRAFT_534469" /product="GroES-like protein" /transcript_id="XM_033749187.1" PFAM_domain complement(join(9743..9959,10055..10089)) /aSDomain="ADH_zinc_N" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00107.29" /description="Zinc-binding dehydrogenase" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_534469_0086" /evalue="8.40E-11" /label="EJ05DRAFT_534469" /locus_tag="EJ05DRAFT_534469" /protein_end="253" /protein_start="169" /score="42.1" /tool="antismash" /translation="GTGTMATQLLKIAGYTPIVTCSPANNAICESFGAAACFDYRSSTC GADIREYTANSLVSVFDCVTDASTMRMCYEAIGSSGGRY" aSDomain complement(join(9815..9959,10055..10524)) /aSDomain="PKS_ER" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EJ05DRAFT_534469_PKS_ER.1" /evalue="2.30E-24" /label="EJ05DRAFT_534469_PKS_ER.1" /locus_tag="EJ05DRAFT_534469" /protein_end="229" /protein_start="24" /score="77.9" /tool="antismash" /translation="EIPTPKPGMILCQVRSVALSPYDAKIVDYSNTPGAIGGCDFAGIV ASVGEGVTRFKKGDRILAVTFGLNASDKTAGAFAEYALATEDLSCHVPENISFEQASSM GLGIATAGLALFQAPGLALELPRPKSAEDTPSFVLVSGGATGTGTMATQLLKIAGYTPI VTCSPANNAICESFGAAACFDYRSSTCGADIREYTANSLVSV" gene 10802..>12071 /db_xref="GeneID:54488900" /locus_tag="EJ05DRAFT_506686" mRNA join(10802..11059,11124..11211,11267..11338,11389..11561, 11613..11670,11730..11876,11929..>12071) /db_xref="GeneID:54488900" /locus_tag="EJ05DRAFT_506686" /product="glutathione S-transferase" /transcript_id="XM_033747846.1" CDS join(11006..11059,11124..11211,11267..11338,11389..11561, 11613..11670,11730..11876,11929..12071) /codon_start=1 /db_xref="GeneID:54488900" /db_xref="InterPro:IPR004045" /db_xref="InterPro:IPR004046" /db_xref="JGIDB:Psehy1_506686" /gene_functions="biosynthetic-additional (rule-based-clusters) GST_N_3" /gene_functions="biosynthetic-additional (rule-based-clusters) GST_C" /gene_functions="biosynthetic-additional (smcogs) SMCOG1193:glutathione S-transferase (Score: 141.1; E-value: 5.7e-43)" /gene_kind="biosynthetic-additional" /locus_tag="EJ05DRAFT_506686" /product="glutathione S-transferase" /protein_id="XP_033605498.1" /sec_met_domain="GST_N_3 (E-value: 3.2e-06, bitscore: 23.7, seeds: 52, tool: rule-based-clusters)" /sec_met_domain="GST_C (E-value: 1.7e-08, bitscore: 30.8, seeds: 35, tool: rule-based-clusters)" /transl_table=1 /translation="MASNFYLEDTPAEVKNAKGLHLITSNTPNGKKVQIMLEELKELYG TEYTTTIIDLSTNEQKKDWFLKLNPNGRIPVLIDNTQNPPFPVMETSAELLYLFKEEDK KAAFGYTDDYGRSECLQWLFFWHGSGQPIQGQLGWFSRNAKDNEVAINRFKNEVLRIYG VLELHLSGKYTGQAKEYLAGKGAGKYSVADISTWPWLDSWHKMDQITQEDMDNFPHLQK WIERIGQRPAVKRGTDPKTWAI" PFAM_domain join(11163..11211,11267..11338,11389..11468) /aSDomain="GST_N" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF02798.23" /description="Glutathione S-transferase, N-terminal domain" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_506686_0087" /evalue="5.90E-08" /label="EJ05DRAFT_506686" /locus_tag="EJ05DRAFT_506686" /protein_end="98" /protein_start="31" /score="33.1" /tool="antismash" /translation="KVQIMLEELKELYGTEYTTTIIDLSTNEQKKDWFLKLNPNGRIPV LIDNTQNPPFPVMETSAELLYL" PFAM_domain join(11747..11876,11929..12029) /aSDomain="GST_C" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00043.28" /description="Glutathione S-transferase, C-terminal domain" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_506686_0088" /evalue="6.40E-07" /label="EJ05DRAFT_506686" /locus_tag="EJ05DRAFT_506686" /protein_end="231" /protein_start="154" /score="29.6" /tool="antismash" /translation="KNEVLRIYGVLELHLSGKYTGQAKEYLAGKGAGKYSVADISTWPW LDSWHKMDQITQEDMDNFPHLQKWIERIGQRP" gene 12507..14039 /db_xref="GeneID:54488901" /locus_tag="EJ05DRAFT_506687" mRNA join(12507..12868,12920..14039) /db_xref="GeneID:54488901" /locus_tag="EJ05DRAFT_506687" /product="alpha/beta-hydrolase" /transcript_id="XM_033747847.1" CDS join(12634..12868,12920..13641) /codon_start=1 /db_xref="GeneID:54488901" /db_xref="InterPro:IPR002925" /db_xref="JGIDB:Psehy1_506687" /locus_tag="EJ05DRAFT_506687" /product="alpha/beta-hydrolase" /protein_id="XP_033605499.1" /transl_table=1 /translation="MSCPDCFLGEVSKGQPTGKELEIHGVQTYVTGPEAGVSPKGIIVY ITDAFGYDFVNNRVLCDQYAKRGFLVYCPDFMNGRSMSPSIIAPMHTILEKKSWLYTIF VKPFILVKVLYHLIPWFMTCSIAKTEAGVIKYFTALRTSPPPFQTRDLKIGAAGFCWGG KHTVTLAQDYPDHRVTRHSSQSTSSAPEPLIDAAFLVHPTFIKVPEDIDAIKIPISWSV GEEDLQMKTDDIKKMKAILESKQDAEHEVILIPGAKHGYAVRTDPEDKVQMAAAEQAEQ QAVSWFSRRFTRTPRTDASPVVQRPAQDHSASLSSES" PFAM_domain join(12712..12868,12920..13551) /aSDomain="DLH" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF01738.21" /db_xref="GO:0016787" /description="Dienelactone hydrolase family" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_506687_0089" /evalue="1.10E-19" /gene_ontologies="GO:0016787: hydrolase activity" /label="EJ05DRAFT_506687" /locus_tag="EJ05DRAFT_506687" /protein_end="289" /protein_start="26" /score="71.0" /tool="antismash" /translation="QTYVTGPEAGVSPKGIIVYITDAFGYDFVNNRVLCDQYAKRGFLV YCPDFMNGRSMSPSIIAPMHTILEKKSWLYTIFVKPFILVKVLYHLIPWFMTCSIAKTE AGVIKYFTALRTSPPPFQTRDLKIGAAGFCWGGKHTVTLAQDYPDHRVTRHSSQSTSSA PEPLIDAAFLVHPTFIKVPEDIDAIKIPISWSVGEEDLQMKTDDIKKMKAILESKQDAE HEVILIPGAKHGYAVRTDPEDKVQMAAAEQAEQQAVSWFSR" CDS complement(14206..14781) /codon_start=1 /db_xref="GeneID:54490242" /db_xref="JGIDB:Psehy1_534472" /locus_tag="EJ05DRAFT_534472" /note="expressed protein" /product="uncharacterized protein" /protein_id="XP_033605500.1" /transl_table=1 /translation="MVAKAPRFPSVFGSQEQKEAFEQTERDVKELQGESFSFKDAQGNF LGPFGVLCYTPSTFKPFLSYSKSYYTLPHLTPKERELTTLATVSVTKSDYVEYAHQKIG ISLGLTQDQVERASAGHLPKGLSDREECVYELALSVARGFGNIKDKQFDSAVALLGKEG VAALAQLVGGYLLISTMESVAGGSVPES" gene complement(<14206..14829) /db_xref="GeneID:54490242" /locus_tag="EJ05DRAFT_534472" mRNA complement(<14206..14829) /db_xref="GeneID:54490242" /locus_tag="EJ05DRAFT_534472" /product="uncharacterized protein" /transcript_id="XM_033749188.1" gene <15189..>16190 /db_xref="GeneID:54488902" /locus_tag="EJ05DRAFT_506689" mRNA join(<15189..15299,15362..15484,15552..>16190) /db_xref="GeneID:54488902" /locus_tag="EJ05DRAFT_506689" /product="peptidase S15" /transcript_id="XM_033747848.1" CDS join(15189..15299,15362..15484,15552..16190) /codon_start=1 /db_xref="GeneID:54488902" /db_xref="JGIDB:Psehy1_506689" /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (rule-based-clusters) Peptidase_S9" /gene_kind="biosynthetic-additional" /locus_tag="EJ05DRAFT_506689" /product="peptidase S15" /protein_id="XP_033605501.1" /sec_met_domain="PF00561 (E-value: 6.3e-06, bitscore: 22.2, seeds: 48, tool: rule-based-clusters)" /sec_met_domain="Peptidase_S9 (E-value: 2.8e-06, bitscore: 23.1, seeds: 64, tool: rule-based-clusters)" /transl_table=1 /translation="MAPTREDIEFKTLAGITLRGWLYPAEKRGPGIILSAGFNMPKDVV VPDIAEWYHKRGFTALIFDTYGIGASDGLPRHDSDMLRRIDDFTDSVTWLSQHPLIDPE KIAVWGLCFDGNIMLATAAYDRRIAAVVTVAPMIDVTGDPERREAIFELGLADRAAQLA GEDPMYLPLVDEDGMTPLGQFLGNFFTTMDSMKMPIENRVTVHTYMRCLNWNILHLLPK ISPTPVIMVTPELDQVFPASRQKEAFDLLNEPKEHCLLVGKHHFDWMFGDMDNAFSPQY EFLKKHLRL" PFAM_domain join(15407..15484,15552..15770) /aSDomain="Peptidase_S15" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF02129.21" /db_xref="GO:0016787" /description="X-Pro dipeptidyl-peptidase (S15 family)" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_506689_0090" /evalue="5.70E-09" /gene_ontologies="GO:0016787: hydrolase activity" /label="EJ05DRAFT_506689" /locus_tag="EJ05DRAFT_506689" /protein_end="151" /protein_start="52" /score="36.1" /tool="antismash" /translation="YHKRGFTALIFDTYGIGASDGLPRHDSDMLRRIDDFTDSVTWLSQ HPLIDPEKIAVWGLCFDGNIMLATAAYDRRIAAVVTVAPMIDVTGDPERREAIF" gene 16619..18053 /db_xref="GeneID:54484140" /locus_tag="EJ05DRAFT_471991" mRNA 16619..18053 /db_xref="GeneID:54484140" /locus_tag="EJ05DRAFT_471991" /product="FAD/NAD(P)-binding domain-containing protein" /transcript_id="XM_033743086.1" CDS 16711..17988 /codon_start=1 /db_xref="GeneID:54484140" /db_xref="InterPro:IPR002938" /db_xref="JGIDB:Psehy1_471991" /gene_functions="other (smcogs) SMCOG1087:hypothetical protein (Score: 209.2; E-value: 2e-63)" /gene_kind="other" /locus_tag="EJ05DRAFT_471991" /product="FAD/NAD(P)-binding domain-containing protein" /protein_id="XP_033605502.1" /transl_table=1 /translation="MVSSVIPESISIIGASVGGLTLGIVLKKYGIQPRIFESREPGYDF GGAVSLTPSTLRIIDSIGAYSRIKPQGFSFEAMTFLTDPERETTGKFYFGHKDVYGYDG LRITRKALLHELTEMANDAGVEINYGKKFTKIVNETTDGVIFEFADGSQEKAQMLIGSD GIHSKVRSCIFPDIHPHYSGFIGLTYCFPRDNVRIDEGFPLPVSLRGSQGDGAIMLQPQ TEGGKEIFVGRQFKFEEKDRSGWDSLLQEKKTLIATLQRDSAAWTPLIQNVLAQASTPE AHFLNVWPFYTVPKMERWHSSAGKVLIIGDAAHAIPPSAGQGANQAFEDGYSLAIFLAS LKNVRVSLLDALKTWEAYRMKRVDDVLKITNRLLTIRMTEEELASVPKHMQWELDGSEA GKSQLGWLYLADIDRDIKSLVESLHM" PFAM_domain 16741..17799 /aSDomain="FAD_binding_3" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF01494.22" /db_xref="GO:0071949" /description="FAD binding domain" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_471991_0091" /evalue="7.70E-29" /gene_ontologies="GO:0071949: FAD binding" /label="EJ05DRAFT_471991" /locus_tag="EJ05DRAFT_471991" /protein_end="363" /protein_start="10" /score="101.2" /tool="antismash" /translation="SIIGASVGGLTLGIVLKKYGIQPRIFESREPGYDFGGAVSLTPST LRIIDSIGAYSRIKPQGFSFEAMTFLTDPERETTGKFYFGHKDVYGYDGLRITRKALLH ELTEMANDAGVEINYGKKFTKIVNETTDGVIFEFADGSQEKAQMLIGSDGIHSKVRSCI FPDIHPHYSGFIGLTYCFPRDNVRIDEGFPLPVSLRGSQGDGAIMLQPQTEGGKEIFVG RQFKFEEKDRSGWDSLLQEKKTLIATLQRDSAAWTPLIQNVLAQASTPEAHFLNVWPFY TVPKMERWHSSAGKVLIIGDAAHAIPPSAGQGANQAFEDGYSLAIFLASLKNVRVSLLD ALKTWEAYRMKRV" gene complement(<18324..>19397) /db_xref="GeneID:54486175" /locus_tag="EJ05DRAFT_481900" mRNA complement(join(<18324..18956,19024..19191,19281..>19397)) /db_xref="GeneID:54486175" /locus_tag="EJ05DRAFT_481900" /product="peptidase S15" /transcript_id="XM_033745121.1" CDS complement(join(18324..18956,19024..19191,19281..19397)) /codon_start=1 /db_xref="GeneID:54486175" /db_xref="JGIDB:Psehy1_481900" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_kind="biosynthetic-additional" /locus_tag="EJ05DRAFT_481900" /product="peptidase S15" /protein_id="XP_033605503.1" /sec_met_domain="Abhydrolase_6 (E-value: 3.5e-08, bitscore: 30.5, seeds: 455, tool: rule-based-clusters)" /transl_table=1 /translation="MAAEQERRDVEFKTFDGLTLRGWLFVGPKGGPAVIVNGAFMCPRE IFVANIAAWFGRHGLTALVYDARSIGASDGMPRTDLDPQKMAEDNSDAVTFLQNDGWVD PNRIAVWGFFYSSGIALEAAAFDRRIKAVIAQGLMPEWYLDPKDQEDLVARAVEDRANQ LRGEPPAYMPLLNEKGEHFLLFNYLAKMTPEQQAHLPNWIVGAKKAASTFRDSLTIQSF YRHAKWKPIHLFASVSPTPVMILTPENDEIVPPEYQKSIYDSLQSPQKRFQIVKDRGHA NFLSVDIDELLTGQLAFLKDVLGF" PFAM_domain complement(join(18759..18956,19024..19146)) /aSDomain="Peptidase_S15" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF02129.21" /db_xref="GO:0016787" /description="X-Pro dipeptidyl-peptidase (S15 family)" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_481900_0092" /evalue="2.10E-05" /gene_ontologies="GO:0016787: hydrolase activity" /label="EJ05DRAFT_481900" /locus_tag="EJ05DRAFT_481900" /protein_end="161" /protein_start="54" /score="24.4" /tool="antismash" /translation="FGRHGLTALVYDARSIGASDGMPRTDLDPQKMAEDNSDAVTFLQN DGWVDPNRIAVWGFFYSSGIALEAAAFDRRIKAVIAQGLMPEWYLDPKDQEDLVARAVE DRA" CDS join(20001..20204,20269..20745,20805..20985,21036..21167, 21219..21517,21568..27951) /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (15-445). E-value: 1.2e-169. Score: 556.6. Matches aSDomain: nrpspksdomains_EJ05DRAFT_459880_PKS_KS.1" /NRPS_PKS="Domain: PKS_AT (549-870). E-value: 8.3e-91. Score: 296.3. Matches aSDomain: nrpspksdomains_EJ05DRAFT_459880_PKS_AT.1" /NRPS_PKS="Domain: PKS_DH (946-1128). E-value: 2e-18. Score: 59.2. Matches aSDomain: nrpspksdomains_EJ05DRAFT_459880_PKS_DH.1" /NRPS_PKS="Domain: cMT (1382-1586). E-value: 6.8e-87. Score: 283.3. Matches aSDomain: nrpspksdomains_EJ05DRAFT_459880_cMT.1" /NRPS_PKS="Domain: PKS_KR (1829-2002). E-value: 4.6e-51. Score: 165.2. Matches aSDomain: nrpspksdomains_EJ05DRAFT_459880_PKS_KR.1" /NRPS_PKS="Domain: PKS_PP (2107-2175). E-value: 1.5e-09. Score: 30.0. Matches aSDomain: nrpspksdomains_EJ05DRAFT_459880_PKS_PP.1" /NRPS_PKS="Domain: TD (2247-2471). E-value: 9e-48. Score: 154.4. Matches aSDomain: nrpspksdomains_EJ05DRAFT_459880_TD.1" /codon_start=1 /db_xref="GeneID:54483640" /db_xref="InterPro:IPR013120" /db_xref="InterPro:IPR013217" /db_xref="InterPro:IPR013968" /db_xref="InterPro:IPR014030" /db_xref="InterPro:IPR014031" /db_xref="InterPro:IPR014043" /db_xref="JGIDB:Psehy1_459880" /gene_functions="biosynthetic (rule-based-clusters) T1PKS: PKS_AT" /gene_functions="biosynthetic (rule-based-clusters) T1PKS: itr_KS" /gene_functions="biosynthetic-additional (rule-based-clusters) adh_short" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) NAD_binding_4" /gene_functions="biosynthetic-additional (smcogs) SMCOG1022:Beta-ketoacyl synthase (Score: 224; E-value: 5.7e-68)" /gene_kind="biosynthetic" /locus_tag="EJ05DRAFT_459880" /product="uncharacterized protein" /protein_id="XP_033605504.1" /sec_met_domain="itr_KS (E-value: 8.8e-172, bitscore: 567.8, seeds: 96, tool: rule-based-clusters)" /sec_met_domain="PKS_AT (E-value: 1.8e-89, bitscore: 296.3, seeds: 1682, tool: rule-based-clusters)" /sec_met_domain="adh_short (E-value: 2.3e-43, bitscore: 144.4, seeds: 230, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 2.4e-07, bitscore: 27.4, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="NAD_binding_4 (E-value: 1.5e-33, bitscore: 112.2, seeds: 102, tool: rule-based-clusters)" /transl_table=1 /translation="MGSYPQSNDGPLREPIAIVGSSCRFPGGATSPSKLWDLLSDPRDL VQEIPASRFDPKVFYHENSQHHGSMNTKYAYILQDEPRLFDRDFFNISPKEAEAMDPQQ RCLLETVYEGVESAGYSIPQLQGSSTGVFVGATCFDYQSIAMRGLDSLPQYYATGGSMA ILANRLSYFFDWRGPSLACDTACSSSLVALHQAVLSLRSGEINMAVAAGANLILGPELF IAYSNLNMLSPNGRSYMWDSSADGYVRGEGFASVILKTLSQAVADGDHIECIIRETGVN SDGRTPGITMPSAEAQSQLIRDTYKRCGLDPVRNRPHYFEAHGTGTPAGDPIEARAIHD TFFPGHPGQNDGHLFVGSLKTIIGHTEGTAGLAGVLKASLAVQHGQIPGNLHFKELNPK IQPFYKHLRVPTGLTSWPTLPKGEPRRVSVNSFGFGGTNAHAIIESWDGAYDRYASLSN PGGLVVLSANSAQALAAKATTLAEYLRKHPATDLGRLARTLFQRGDFLFRASFAAVSAE QLAGKLESRAEALKKTARIPAIPKSLPPRILGVFTGQGAQWATMGKELYEASSVFRKTL DQLQNSLDTLPESDRPNWKLIDELSAPRETSRVGVAAISQPICTALQVALVDVIRAAGV DFAAVVGHSSGEIAASYCAGYLDARDAIRVAYYRGFHSNLAQCDGKRGKMMAVGMGLDA ALAFCAEFGTNLKVAANNSTTSCTLAGDANLIDEAKAQLDEDKVFARVLAVDTAYHSHH MLPCAGPYLESLRQCGVKTLKGPRKCEWYSSVWGSNGRSRSFNDEKGMELLEGQYWVDN LTNTVLFSQAVNRAVSEESSVLDLALEVGPHPALKGPSSEVIKSLTGLNLPYSGVLKRG ESAVEAFTDSLGLIWSSFPSSRPLITFDGILRALPLASPKKPSILKGLPTYPWDHDTLN WRESRASRLFRGGQPPHELLGRPTILGEQARREVYWRQVFKLNELPWVRGHTIQGEVLF PATGYLTMAYEAAVRLVDDQESIRLVELHDIEIVRTMGMQEDSSGLEVLFTVRVTGQTD SCITAEVACYSGDITTAKLDGPVSSLTAHFSGGVRLLLGPAQSGDLPTRKKPLLPMNTL DMDQFYGYLSKVGYNYSDSFKAHSVDRHLNHAVVSVSTPAESASTCPSMHPAVLDTAIQ GLLAAFSYPEDGRLGTVYLPTGIDSVRIKVASDSPDVLMADSALTSSGEKGLTGEVDLF NASDSTVQVQMRGVSWTALNQGRERWLYASEEWVRDASHGIEPTLKTKFSPEDEVLRKL LVRVAHFYLRALRSQIKPSELIVMGKHRRHMMRWVREHLFPQIEAGKVPDIEPEWANDT LEEVQQWSAPYIEAGNNDMLILHAVGKNLPAIARGTMPALQVMLKDGMLDRLYVEGVGF ADGNLDLGPLVKQVAHRYPRMKVLEVGAGTGGTTRSVLESVGDHYGSYTYTDISAGFFE PAKAKFSEHTSKLTFKMLNIEKDPIEQGFVEGSYDMVVASNALHATRCLKDTLSHCRQL LRPGGYLVLLEITTNHLPIQLIMGTLPGWFLGADEGRVWVPTLSLEEWDKILKETGFSG VDTSSTPSFCSVIMSRATTETFEAIREPLLTAPRPAAQPLGPVLIVSNAASELASGSQA LLTSIEGVTQCDITGLEDIKCPVGAVVLCLSDLDSPVFEEMTEARFEAMQTVFRNASVV LWVTSGATSGKNPLANVTVGLGRTLLAERSDLQLQFLDVDDPTSLEPSLLAKLLLRLTG TDQADLSEMLWTQEPLLALKDGAFYIPRVLPLQVTSRQSTTEPSVEVATQDSVENVVTE TGLDEHKSTFADNKTYILFGMTGDLGISIARWMVENGARNVVLTSRHPDVPEGVFEFMS QKGAILRAISADVTDKEGLNKVYAEIKSTLPPIGGIINGAMVLRDRPFVDTTWDDFEAV LAPKVAGTRNLDELFGESEALDFFIVLSSATSIVGNIGQSAYSAANHYMTSLVKRRQGR GLVGSVVVIGFLTGLGYIFRSDKKHRAAIEKSLLPRLDRQAETDLHDMLIKAIECGRPE SNLPSELITGIRKKFTEAWHEDVRLSGYLLQEGDKEEGASQEQADGNVKVDIQLAATKD PKEGLAILIKCFSQALGNMLQLDPAQINADMPVAEHGVDSLVSVRIREWFLKELGVDVP VLKLMSTNHTMSRVCEDAFAGWRKLRSGSQAESQTATKTHDDPEMDWKKEVAGLIDGIP ALVAAGVDSADVPRTSARRVVLTGCTGFLGTHILRNLVADPNTAEVHCLCLRSRPLRVK DARIHEYKGDLVKPFLGLSAADFKRLSQTADLIIHVGADVAHLKSYEMMRAANVISTQT LLAMATPRHVPVHFVSSSSVAMLQKDTAELWEVPPSSFWPPSDAESLMKNAIGYAASKW MGEILLERAEGVPGVVHRFPNIMGPDAPEEIPLVALDRYCMKLRAVPALDPKQWVGELD VIEVTDVVPELMATAYAHDPSKSFAIHNYCSENRYLLSDLVSMYKQKLGGTVEVLPTPE WMRRAKDLGMPKGVEATWTGHNEVFISPVLHKGQK" gene <20001..28003 /db_xref="GeneID:54483640" /locus_tag="EJ05DRAFT_459880" mRNA join(<20001..20204,20269..20745,20805..20985,21036..21167, 21219..21517,21568..28003) /db_xref="GeneID:54483640" /locus_tag="EJ05DRAFT_459880" /product="uncharacterized protein" /transcript_id="XM_033742586.1" PFAM_domain join(20040..20204,20269..20745,20805..20915) /aSDomain="ketoacyl-synt" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00109.29" /description="Beta-ketoacyl synthase, N-terminal domain" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_459880_0093" /evalue="7.40E-73" /label="EJ05DRAFT_459880" /locus_tag="EJ05DRAFT_459880" /protein_end="264" /protein_start="13" /score="245.3" /tool="antismash" /translation="EPIAIVGSSCRFPGGATSPSKLWDLLSDPRDLVQEIPASRFDPKV FYHENSQHHGSMNTKYAYILQDEPRLFDRDFFNISPKEAEAMDPQQRCLLETVYEGVES AGYSIPQLQGSSTGVFVGATCFDYQSIAMRGLDSLPQYYATGGSMAILANRLSYFFDWR GPSLACDTACSSSLVALHQAVLSLRSGEINMAVAAGANLILGPELFIAYSNLNMLSPNG RSYMWDSSADGYVRGEGFASVILKTLSQA" aSDomain join(20046..20204,20269..20745,20805..20985,21036..21167, 21219..21517,21568..21609) /ASF="found active site cysteine: True, scaffold matched GSSS: True" /ASF="found active site histidines: True" /aSDomain="PKS_KS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EJ05DRAFT_459880_PKS_KS.1" /domain_subtypes="Iterative-KS" /evalue="1.20E-169" /label="EJ05DRAFT_459880_PKS_KS.1" /locus_tag="EJ05DRAFT_459880" /protein_end="445" /protein_start="15" /score="556.6" /tool="antismash" /translation="IAIVGSSCRFPGGATSPSKLWDLLSDPRDLVQEIPASRFDPKVFY HENSQHHGSMNTKYAYILQDEPRLFDRDFFNISPKEAEAMDPQQRCLLETVYEGVESAG YSIPQLQGSSTGVFVGATCFDYQSIAMRGLDSLPQYYATGGSMAILANRLSYFFDWRGP SLACDTACSSSLVALHQAVLSLRSGEINMAVAAGANLILGPELFIAYSNLNMLSPNGRS YMWDSSADGYVRGEGFASVILKTLSQAVADGDHIECIIRETGVNSDGRTPGITMPSAEA QSQLIRDTYKRCGLDPVRNRPHYFEAHGTGTPAGDPIEARAIHDTFFPGHPGQNDGHLF VGSLKTIIGHTEGTAGLAGVLKASLAVQHGQIPGNLHFKELNPKIQPFYKHLRVPTGLT SWPTLPKGEPRRVSVNSFGFGGTNAHAIIES" aSModule 20046..27687 /complete /domains="nrpspksdomains_EJ05DRAFT_459880_PKS_KS.1" /domains="nrpspksdomains_EJ05DRAFT_459880_PKS_AT.1" /domains="nrpspksdomains_EJ05DRAFT_459880_PKS_DH.1" /domains="nrpspksdomains_EJ05DRAFT_459880_cMT.1" /domains="nrpspksdomains_EJ05DRAFT_459880_PKS_KR.1" /domains="nrpspksdomains_EJ05DRAFT_459880_PKS_PP.1" /domains="nrpspksdomains_EJ05DRAFT_459880_TD.1" /final_module /iterative /locus_tags="EJ05DRAFT_459880" /monomer_pairings="pk -> Me-pk" /tool="antismash" /type="pks" CDS_motif 20593..20640 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_459880_0001" /evalue="1.70E-05" /label="PKSI-KS_m3" /locus_tag="EJ05DRAFT_459880" /protein_end="192" /protein_start="176" /score="16.9" /tool="antismash" /translation="GPSLACDTACSSSLVA" CDS_motif 20841..20879 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_459880_0002" /evalue="3.50E-04" /label="PKSI-KS_m4" /locus_tag="EJ05DRAFT_459880" /protein_end="252" /protein_start="239" /score="13.6" /tool="antismash" /translation="WDSSADGYVRGEG" PFAM_domain join(20940..20985,21036..21167,21219..21403) /aSDomain="Ketoacyl-synt_C" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF02801.25" /description="Beta-ketoacyl synthase, C-terminal domain" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_459880_0094" /evalue="1.00E-29" /label="EJ05DRAFT_459880" /locus_tag="EJ05DRAFT_459880" /protein_end="393" /protein_start="272" /score="103.1" /tool="antismash" /translation="CIIRETGVNSDGRTPGITMPSAEAQSQLIRDTYKRCGLDPVRNRP HYFEAHGTGTPAGDPIEARAIHDTFFPGHPGQNDGHLFVGSLKTIIGHTEGTAGLAGVL KASLAVQHGQIPGNLHF" CDS_motif join(21128..21167,21219..21226) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_459880_0003" /evalue="6.90E-04" /label="PKSI-KS_m5" /locus_tag="EJ05DRAFT_459880" /protein_end="334" /protein_start="318" /score="12.0" /tool="antismash" /translation="YFEAHGTGTPAGDPIE" PFAM_domain join(21413..21517,21568..21750) /aSDomain="KAsynt_C_assoc" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF16197.8" /description="Ketoacyl-synthetase C-terminal extension" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_459880_0095" /evalue="2.50E-14" /label="EJ05DRAFT_459880" /locus_tag="EJ05DRAFT_459880" /protein_end="492" /protein_start="396" /score="53.8" /tool="antismash" /translation="NPKIQPFYKHLRVPTGLTSWPTLPKGEPRRVSVNSFGFGGTNAHA IIESWDGAYDRYASLSNPGGLVVLSANSAQALAAKATTLAEYLRKHPATDL" PFAM_domain 21922..22839 /aSDomain="Acyl_transf_1" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00698.24" /description="Acyl transferase domain" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_459880_0096" /evalue="3.20E-39" /label="EJ05DRAFT_459880" /locus_tag="EJ05DRAFT_459880" /protein_end="855" /protein_start="549" /score="135.4" /tool="antismash" /translation="VFTGQGAQWATMGKELYEASSVFRKTLDQLQNSLDTLPESDRPNW KLIDELSAPRETSRVGVAAISQPICTALQVALVDVIRAAGVDFAAVVGHSSGEIAASYC AGYLDARDAIRVAYYRGFHSNLAQCDGKRGKMMAVGMGLDAALAFCAEFGTNLKVAANN STTSCTLAGDANLIDEAKAQLDEDKVFARVLAVDTAYHSHHMLPCAGPYLESLRQCGVK TLKGPRKCEWYSSVWGSNGRSRSFNDEKGMELLEGQYWVDNLTNTVLFSQAVNRAVSEE SSVLDLALEVGPHPALKGPSSEVIK" aSDomain 21922..22884 /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific" /ASF="found active site serine: True, scaffold matched GHGE: True" /aSDomain="PKS_AT" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EJ05DRAFT_459880_PKS_AT.1" /evalue="8.30E-91" /label="EJ05DRAFT_459880_PKS_AT.1" /locus_tag="EJ05DRAFT_459880" /protein_end="870" /protein_start="549" /score="296.3" /specificity="substrate consensus: pk" /specificity="PKS signature: Malonyl-CoA" /specificity="Minowa: mmal" /tool="antismash" /translation="VFTGQGAQWATMGKELYEASSVFRKTLDQLQNSLDTLPESDRPNW KLIDELSAPRETSRVGVAAISQPICTALQVALVDVIRAAGVDFAAVVGHSSGEIAASYC AGYLDARDAIRVAYYRGFHSNLAQCDGKRGKMMAVGMGLDAALAFCAEFGTNLKVAANN STTSCTLAGDANLIDEAKAQLDEDKVFARVLAVDTAYHSHHMLPCAGPYLESLRQCGVK TLKGPRKCEWYSSVWGSNGRSRSFNDEKGMELLEGQYWVDNLTNTVLFSQAVNRAVSEE SSVLDLALEVGPHPALKGPSSEVIKSLTGLNLPYSGVLKR" CDS_motif 21925..21972 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_459880_0004" /evalue="1.30E-05" /label="PKSI-AT-M_m1" /locus_tag="EJ05DRAFT_459880" /protein_end="566" /protein_start="550" /score="17.7" /tool="antismash" /translation="FTGQGAQWATMGKELY" CDS_motif 22174..22281 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_459880_0005" /evalue="1.80E-10" /label="PKSI-AT-mM_m3" /locus_tag="EJ05DRAFT_459880" /protein_end="669" /protein_start="633" /score="33.2" /tool="antismash" /translation="GVDFAAVVGHSSGEIAASYCAGYLDARDAIRVAYYR" CDS_motif 22684..22731 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_459880_0006" /evalue="1.90E-03" /label="PKSI-AT-mM_m8" /locus_tag="EJ05DRAFT_459880" /protein_end="819" /protein_start="803" /score="10.9" /tool="antismash" /translation="LEGQYWVDNLTNTVLF" aSDomain 23113..23658 /ASF="catalytic triad H,G,P inconclusive" /aSDomain="PKS_DH" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EJ05DRAFT_459880_PKS_DH.1" /evalue="2.00E-18" /label="EJ05DRAFT_459880_PKS_DH.1" /locus_tag="EJ05DRAFT_459880" /protein_end="1128" /protein_start="946" /score="59.2" /tool="antismash" /translation="HELLGRPTILGEQARREVYWRQVFKLNELPWVRGHTIQGEVLFPA TGYLTMAYEAAVRLVDDQESIRLVELHDIEIVRTMGMQEDSSGLEVLFTVRVTGQTDSC ITAEVACYSGDITTAKLDGPVSSLTAHFSGGVRLLLGPAQSGDLPTRKKPLLPMNTLDM DQFYGYLSKVGYNYSDSFK" PFAM_domain 23113..24018 /aSDomain="PS-DH" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF14765.9" /description="Polyketide synthase dehydratase" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_459880_0097" /evalue="6.50E-47" /label="EJ05DRAFT_459880" /locus_tag="EJ05DRAFT_459880" /protein_end="1248" /protein_start="946" /score="160.3" /tool="antismash" /translation="HELLGRPTILGEQARREVYWRQVFKLNELPWVRGHTIQGEVLFPA TGYLTMAYEAAVRLVDDQESIRLVELHDIEIVRTMGMQEDSSGLEVLFTVRVTGQTDSC ITAEVACYSGDITTAKLDGPVSSLTAHFSGGVRLLLGPAQSGDLPTRKKPLLPMNTLDM DQFYGYLSKVGYNYSDSFKAHSVDRHLNHAVVSVSTPAESASTCPSMHPAVLDTAIQGL LAAFSYPEDGRLGTVYLPTGIDSVRIKVASDSPDVLMADSALTSSGEKGLTGEVDLFNA SDSTVQVQMRGVSWTALNQGR" CDS_motif 23203..23280 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_459880_0007" /evalue="1.00E-10" /label="PKSI-DH_m2" /locus_tag="EJ05DRAFT_459880" /protein_end="1002" /protein_start="976" /score="34.0" /tool="antismash" /translation="WVRGHTIQGEVLFPATGYLTMAYEAA" aSDomain 24421..25032 /aSDomain="MT" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EJ05DRAFT_459880_cMT.1" /domain_subtypes="cMT" /evalue="6.80E-87" /label="EJ05DRAFT_459880_cMT.1" /locus_tag="EJ05DRAFT_459880" /protein_end="1586" /protein_start="1382" /score="283.3" /tool="antismash" /translation="LQVMLKDGMLDRLYVEGVGFADGNLDLGPLVKQVAHRYPRMKVLE VGAGTGGTTRSVLESVGDHYGSYTYTDISAGFFEPAKAKFSEHTSKLTFKMLNIEKDPI EQGFVEGSYDMVVASNALHATRCLKDTLSHCRQLLRPGGYLVLLEITTNHLPIQLIMGT LPGWFLGADEGRVWVPTLSLEEWDKILKETGFSGVDTSSTP" PFAM_domain 24550..24855 /aSDomain="Methyltransf_12" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF08242.15" /description="Methyltransferase domain" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_459880_0098" /evalue="1.40E-18" /label="EJ05DRAFT_459880" /locus_tag="EJ05DRAFT_459880" /protein_end="1527" /protein_start="1425" /score="67.6" /tool="antismash" /translation="LEVGAGTGGTTRSVLESVGDHYGSYTYTDISAGFFEPAKAKFSEH TSKLTFKMLNIEKDPIEQGFVEGSYDMVVASNALHATRCLKDTLSHCRQLLRPGGYL" CDS_motif 25762..25857 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_459880_0008" /evalue="2.00E-14" /label="PKSI-KR_m1" /locus_tag="EJ05DRAFT_459880" /protein_end="1861" /protein_start="1829" /score="46.1" /tool="antismash" /translation="TYILFGMTGDLGISIARWMVENGARNVVLTSR" aSDomain 25762..26280 /ASF="KR domain putatively catalyzing D-configuration product formation" /ASF="catalytic triad S,Y,N found: True" /aSDomain="PKS_KR" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EJ05DRAFT_459880_PKS_KR.1" /evalue="4.60E-51" /label="EJ05DRAFT_459880_PKS_KR.1" /locus_tag="EJ05DRAFT_459880" /protein_end="2002" /protein_start="1829" /score="165.2" /specificity="KR activity: active" /specificity="KR stereochemistry: (unknown)" /tool="antismash" /translation="TYILFGMTGDLGISIARWMVENGARNVVLTSRHPDVPEGVFEFMS QKGAILRAISADVTDKEGLNKVYAEIKSTLPPIGGIINGAMVLRDRPFVDTTWDDFEAV LAPKVAGTRNLDELFGESEALDFFIVLSSATSIVGNIGQSAYSAANHYMTSLVKRRQGR GLVGSVVVIG" PFAM_domain 25762..26286 /aSDomain="KR" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF08659.13" /description="KR domain" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_459880_0099" /evalue="1.50E-48" /label="EJ05DRAFT_459880" /locus_tag="EJ05DRAFT_459880" /protein_end="2004" /protein_start="1829" /score="165.2" /tool="antismash" /translation="TYILFGMTGDLGISIARWMVENGARNVVLTSRHPDVPEGVFEFMS QKGAILRAISADVTDKEGLNKVYAEIKSTLPPIGGIINGAMVLRDRPFVDTTWDDFEAV LAPKVAGTRNLDELFGESEALDFFIVLSSATSIVGNIGQSAYSAANHYMTSLVKRRQGR GLVGSVVVIGFL" CDS_motif 26134..26241 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_459880_0009" /evalue="3.00E-16" /label="PKSI-KR_m4" /locus_tag="EJ05DRAFT_459880" /protein_end="1989" /protein_start="1953" /score="51.9" /tool="antismash" /translation="LDFFIVLSSATSIVGNIGQSAYSAANHYMTSLVKRR" aSDomain 26596..26799 /aSDomain="PKS_PP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EJ05DRAFT_459880_PKS_PP.1" /evalue="1.50E-09" /label="EJ05DRAFT_459880_PKS_PP.1" /locus_tag="EJ05DRAFT_459880" /protein_end="2175" /protein_start="2107" /score="30.0" /tool="antismash" /translation="TKDPKEGLAILIKCFSQALGNMLQLDPAQINADMPVAEHGVDSLV SVRIREWFLKELGVDVPVLKLMS" PFAM_domain 26647..26826 /aSDomain="PP-binding" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00550.28" /description="Phosphopantetheine attachment site" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_459880_0100" /evalue="1.90E-06" /label="EJ05DRAFT_459880" /locus_tag="EJ05DRAFT_459880" /protein_end="2184" /protein_start="2124" /score="28.2" /tool="antismash" /translation="ALGNMLQLDPAQINADMPVAEHGVDSLVSVRIREWFLKELGVDVP VLKLMSTNHTMSRVC" aSDomain 27016..27687 /aSDomain="TD" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EJ05DRAFT_459880_TD.1" /evalue="9.00E-48" /label="EJ05DRAFT_459880_TD.1" /locus_tag="EJ05DRAFT_459880" /protein_end="2471" /protein_start="2247" /score="154.4" /tool="antismash" /translation="VVLTGCTGFLGTHILRNLVADPNTAEVHCLCLRSRPLRVKDARIH EYKGDLVKPFLGLSAADFKRLSQTADLIIHVGADVAHLKSYEMMRAANVISTQTLLAMA TPRHVPVHFVSSSSVAMLQKDTAELWEVPPSSFWPPSDAESLMKNAIGYAASKWMGEIL LERAEGVPGVVHRFPNIMGPDAPEEIPLVALDRYCMKLRAVPALDPKQWVGELDVIEVT DV" CDS_motif 27019..27072 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EJ05DRAFT_459880_0010" /evalue="3.10E-01" /label="PKSI-KR_m1" /locus_tag="EJ05DRAFT_459880" /protein_end="2266" /protein_start="2248" /score="3.8" /tool="antismash" /translation="VLTGCTGFLGTHILRNLV" PFAM_domain 27022..27570 /aSDomain="NAD_binding_4" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF07993.15" /description="Male sterility protein" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_459880_0101" /evalue="1.50E-29" /label="EJ05DRAFT_459880" /locus_tag="EJ05DRAFT_459880" /protein_end="2432" /protein_start="2249" /score="103.1" /tool="antismash" /translation="LTGCTGFLGTHILRNLVADPNTAEVHCLCLRSRPLRVKDARIHEY KGDLVKPFLGLSAADFKRLSQTADLIIHVGADVAHLKSYEMMRAANVISTQTLLAMATP RHVPVHFVSSSSVAMLQKDTAELWEVPPSSFWPPSDAESLMKNAIGYAASKWMGEILLE RAEGVPGVVHRFPNIMGPDA" gene complement(28611..30996) /db_xref="GeneID:54484141" /locus_tag="EJ05DRAFT_471995" mRNA complement(join(28611..29162,29245..29975,30071..30483, 30565..30996)) /db_xref="GeneID:54484141" /locus_tag="EJ05DRAFT_471995" /product="MFS general substrate transporter" /transcript_id="XM_033743087.1" CDS complement(join(28855..29162,29245..29975,30071..30483, 30565..30858)) /codon_start=1 /db_xref="GeneID:54484141" /db_xref="InterPro:IPR011701" /db_xref="JGIDB:Psehy1_471995" /gene_functions="transport (smcogs) SMCOG1005:Drug resistance transporter, EmrB/QacA (Score: 307.1; E-value: 2.6e-93)" /gene_kind="transport" /locus_tag="EJ05DRAFT_471995" /product="MFS general substrate transporter" /protein_id="XP_033605505.1" /transl_table=1 /translation="MSPSTPPPRLPEDRTLADMGDNTHQVDPEKEKPNEMSSSASSTDN GVPRSDAPEADGATTEEKPVAEPPKPMTYPKGIEVLFIMLALILSITLISLDQTIVATA IPKITDQFHKLDDISWYGSAYFLTLGAFQSLWGKVYKFFPLKTSFLVAIFIFELGSLIS GVAQNSMTLIVGRAISGLGASGIAPGVYTISAFAAEPTKRATYTSVIGVSYGVAAVCGP LIGGGLTDGASWRWCFYINLPIGGLAAAVILVTFKTPAAAKVVQATLKEKLLQMDFLGA TLTMGASLTLLLALQYGGQTHPWSSSLVIGLIVGFVAIVGVLTAVEIWQGERAMLTPRL MRQRHVWVNGLWGFFFAGAYFVTLYYLPIYFQSIDNASPIGSGVRNIPLIVLFGIATYG SGVIITKTGVAAPYLPVSSVIVTIAAGLFFTMDIGTSTGKWVGYQILGGFGYGLALQVP VIISQAFSAPADIAPTTAIIIWCRSMGGTILLSAAQCGFVNQLVAKLASTAPNLDATLV TATGATDLHRVFTGADLDGVLRAYAWGIKVAFAITIACCGICVPVSMLTRWNNVNAKKQ AASKA" PFAM_domain complement(join(29143..29162,29245..29975,30071..30483, 30565..30600)) /aSDomain="MFS_1" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF07690.19" /db_xref="GO:0022857" /db_xref="GO:0055085" /description="Major Facilitator Superfamily" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_471995_0102" /evalue="2.10E-33" /gene_ontologies="GO:0022857: transmembrane transporter activity" /gene_ontologies="GO:0055085: transmembrane transport" /label="EJ05DRAFT_471995" /locus_tag="EJ05DRAFT_471995" /protein_end="486" /protein_start="86" /score="115.8" /tool="antismash" /translation="LILSITLISLDQTIVATAIPKITDQFHKLDDISWYGSAYFLTLGA FQSLWGKVYKFFPLKTSFLVAIFIFELGSLISGVAQNSMTLIVGRAISGLGASGIAPGV YTISAFAAEPTKRATYTSVIGVSYGVAAVCGPLIGGGLTDGASWRWCFYINLPIGGLAA AVILVTFKTPAAAKVVQATLKEKLLQMDFLGATLTMGASLTLLLALQYGGQTHPWSSSL VIGLIVGFVAIVGVLTAVEIWQGERAMLTPRLMRQRHVWVNGLWGFFFAGAYFVTLYYL PIYFQSIDNASPIGSGVRNIPLIVLFGIATYGSGVIITKTGVAAPYLPVSSVIVTIAAG LFFTMDIGTSTGKWVGYQILGGFGYGLALQVPVIISQAFSAPADIAPTTAIIIWCRSMG G" gene complement(<32561..>33454) /db_xref="GeneID:54486176" /locus_tag="EJ05DRAFT_481903" mRNA complement(<32561..>33454) /db_xref="GeneID:54486176" /locus_tag="EJ05DRAFT_481903" /product="uncharacterized protein" /transcript_id="XM_033745122.1" CDS complement(32561..33454) /codon_start=1 /db_xref="GeneID:54486176" /db_xref="JGIDB:Psehy1_481903" /locus_tag="EJ05DRAFT_481903" /note="expressed protein" /product="uncharacterized protein" /protein_id="XP_033605506.1" /transl_table=1 /translation="MVKNVIGWWPPAPPAPAPPAPPAKKEEKEEIPEIKYRWRYEVIPG DVPLPMSYRHIDYPRDGPTISEHAVRQRWKELLKMKDEKEPDVERKYSTSHRWTTLNPE PKPKDKPSNKFDTPFGPVIIHPPEEPPKEEKKPIHIHLGPPKKEDPPAPHPRFIWDGGP GPRPFCHPVKPCCPPSKDEPPTYVYGCPPPPKEEEKKAPDPAPAPTPPPCQWDSVAKIL GAILALIVIWATLDAAGRIISAIMAPFRMVLVNAPYNPYPGQYQQPYQQPPYPQPPYHQ HAHQHAHQHAHQYHRH" gene complement(<34117..>35941) /db_xref="GeneID:54486177" /locus_tag="EJ05DRAFT_481904" mRNA complement(join(<34117..34226,34283..35138,35321..>35941)) /db_xref="GeneID:54486177" /locus_tag="EJ05DRAFT_481904" /product="WD40 repeat-like protein" /transcript_id="XM_033745123.1" CDS complement(join(34117..34226,34283..35138,35321..35941)) /codon_start=1 /db_xref="GeneID:54486177" /db_xref="InterPro:IPR001680" /db_xref="JGIDB:Psehy1_481904" /gene_functions="other (smcogs) SMCOG1173:WD-40 repeat-containing protein (Score: 55.6; E-value: 6.6e-17)" /gene_kind="other" /locus_tag="EJ05DRAFT_481904" /product="WD40 repeat-like protein" /protein_id="XP_033605507.1" /transl_table=1 /translation="MEREKPHQRRATRQAGGDEADVLDSINDPIKDKLEAVNLKLCRPA FLQSISASRLPSQAASDCSSISPEPTKSTFGFQASKRTQSNLSDTAVEFASRVERIEAA HILTIDLLSHGSAAALTLNHKVCQKLQASVLRAYKAAKSMATDRGFQSFSHGHQDLVLA VDFNYFGTRMVTASSDHRLKVWDRKDDNWNLADSWRAHDAEIVDVKWNGPYAGEILGSV AEDGRFKLWQEDVTEVPQSGRRFKLVTTLTPETKVPYMSLDFKNIFQDTYLALITRDGH LSVYEPLDNNNIAEWQYLHDSYVCATPSRQDEAGFKVCFHHEKLPCWTAVREGLDRKSL SLAVAAMKTVKIFRTDKNRKWYVAAELNDATSIVRDLSWANGSMRGYDIIATASKDGAI RIYELHNAETDKQSASDTTVAIHNGHTDGRSSPRPRGSRAGPSGIGAGLAGASKSNEDS QEVTIPGRVKHLVKKVAELKNHHGAVWRVAFSPMGDLLISTGDDGTIRTWKKGVNDLWK EYSEIDGANED" PFAM_domain complement(join(34177..34226,34283..34343)) /aSDomain="WD40" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00400.35" /db_xref="GO:0005515" /description="WD domain, G-beta repeat" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_481904_0104" /evalue="8.90E-06" /gene_ontologies="GO:0005515: protein binding" /label="EJ05DRAFT_481904" /locus_tag="EJ05DRAFT_481904" /protein_end="509" /protein_start="472" /score="26.5" /tool="antismash" /translation="KVAELKNHHGAVWRVAFSPMGDLLISTGDDGTIRTWK" PFAM_domain complement(35384..35485) /aSDomain="WD40" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00400.35" /db_xref="GO:0005515" /description="WD domain, G-beta repeat" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_481904_0103" /evalue="3.50E-03" /gene_ontologies="GO:0005515: protein binding" /label="EJ05DRAFT_481904" /locus_tag="EJ05DRAFT_481904" /protein_end="186" /protein_start="152" /score="18.3" /tool="antismash" /translation="FSHGHQDLVLAVDFNYFGTRMVTASSDHRLKVWD" gene 36097..37961 /db_xref="GeneID:54483641" /locus_tag="EJ05DRAFT_459886" mRNA join(36097..36497,36558..36738,36795..37008,37058..37961) /db_xref="GeneID:54483641" /locus_tag="EJ05DRAFT_459886" /product="uncharacterized protein" /transcript_id="XM_033742587.1" CDS join(36259..36497,36558..36738,36795..37008,37058..37827) /codon_start=1 /db_xref="GeneID:54483641" /db_xref="InterPro:IPR000715" /db_xref="JGIDB:Psehy1_459886" /gene_functions="biosynthetic-additional (rule-based-clusters) Glycos_transf_4" /gene_kind="biosynthetic-additional" /locus_tag="EJ05DRAFT_459886" /product="uncharacterized protein" /protein_id="XP_033605508.1" /sec_met_domain="Glycos_transf_4 (E-value: 2.1e-32, bitscore: 108.5, seeds: 116, tool: rule-based-clusters)" /transl_table=1 /translation="MTVSTSLSRTETLSLFSLSAACVGIIANTFQGDGEPLIASIAFSG IAYASTYALIRWLGDVFMRAGLKGRDMSKTRTDEIPETMGAVCAVVYLLIIIVFIPFPF YKDIVMATSGGGNRDLVLEVQHVETGRLLHRFPHSKLSSYLSAILSIQSVVLLGVGDDL FDIRWRHKLFIPAFAAIPMLIVYFVDFGVTQIVIPTPLRSYFGALFDLGWLYYAYMAAI SIFCPNSINIFAGINGIEVSQSLVIASLICLNDALYLSPFTEYPHPATDSHLFSLYLLL PFIGVSLALWAHNWYPARVFVGDTYCYFAGMIFAVVGIQGHFSKTLLLLFMPQIFNFIY SAPQLFHIVPCPRHRLPKFNARTGLLECSTAEFRKPLSPLVSAVMRLMHRLRLLRIVEN DAGQITESTNFTIINLWLVWFGPMREDRLAIGLLTMQTIVGLVGLFIRHRLALWVFTAD NLHYTYSSA" PFAM_domain join(36807..37008,37058..37386) /aSDomain="Glycos_transf_4" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00953.24" /db_xref="GO:0016020" /db_xref="GO:0016780" /description="Glycosyl transferase family 4" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_459886_0105" /evalue="7.80E-34" /gene_ontologies="GO:0016020: membrane" /gene_ontologies="GO:0016780: phosphotransferase activity, for other substituted phosphate groups" /label="EJ05DRAFT_459886" /locus_tag="EJ05DRAFT_459886" /protein_end="321" /protein_start="144" /score="117.1" /tool="antismash" /translation="LSAILSIQSVVLLGVGDDLFDIRWRHKLFIPAFAAIPMLIVYFVD FGVTQIVIPTPLRSYFGALFDLGWLYYAYMAAISIFCPNSINIFAGINGIEVSQSLVIA SLICLNDALYLSPFTEYPHPATDSHLFSLYLLLPFIGVSLALWAHNWYPARVFVGDTYC YFAGMIFAVVGIQG" gene 38339..41114 /db_xref="GeneID:54483329" /locus_tag="EJ05DRAFT_447510" mRNA join(38339..38570,38620..38694,38752..41114) /db_xref="GeneID:54483329" /locus_tag="EJ05DRAFT_447510" /product="3-isopropylmalate dehydratase" /transcript_id="XM_033742275.1" CDS join(38439..38570,38620..38694,38752..40878) /codon_start=1 /db_xref="GeneID:54483329" /db_xref="InterPro:IPR000573" /db_xref="InterPro:IPR001030" /db_xref="JGIDB:Psehy1_447510" /locus_tag="EJ05DRAFT_447510" /note="hypothetical protein MYCGRDRAFT_109538" /product="3-isopropylmalate dehydratase" /protein_id="XP_033605509.1" /transl_table=1 /translation="MPGAIKKPQTLYDKVFEAHVVNEQEDGTILLYIDRHLVHEVTSPQ AFEGLRNAGRKVRRPDCTLATTDHNVPTTPRKNFKGVADFIKEDDSRTQCVTLEDNVKA FGLTYFGLGDKRQGIVHIIGPEQGFTLPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEH VLATQTLLTKRSKNMRVQVDGELAPGVSSKDIILHVIGQIGTAGGTGAVIEFCGSAIRN LSMEARMSICNMSIEGGARAGMVAPDETTFEYLKGRPLAPKVDSAEWKKATAYWSSLKS DEGAEYDLDVFIDSKDIAPTVSWGTSPQDVVPITGKVPSPDDFQDEDKRKACIRALDYM GLEAGTPMQEVVLDKVFIGSCTNARIEDLRAAARIVKGRKVASNIKRAMIVPGSGLVKQ QAESEGLDTIFTDAGFEWREAGCSMCLGMNPDILSPKERCASTSNRNFEGRQGAGGRTH LMSPMMAAACAIAGKLADVRKIANFQPSDVAQGSPKVDVAPAHQSDIESDEDLDRIADA PEDSPATVSGNNKSASSSSGGMPKFEKLKGIAAPMDVANIDTDAIIPKQFLKTIKRSGL GSALFYSWRFADDGSEKKDFVLNQEPYRNAKVLVSTGKNFGCGSSREHAPWALLDFGIT CIIAPSFGDIFFNNTFKNGMLPLRLTPEQGLDAVAAEARAGREIEVDLPGQVIRDADGK QIATFEVEEFRKHCLLNGLDDIGLTFQQDDKIKAFEGKRSREYPWLDGSGYLRKHRPGE AVKVEAVPVPKTNRGEVKGEPLEW" aSDomain join(38460..38570,38620..38694,38752..39984) /aSDomain="TIGR00170" /aSTool="tigrfam" /description="leuC: 3-isopropylmalate dehydratase, large subunit" /detection="hmmscan" /domain_id="TIGRFam_EJ05DRAFT_447510_0007" /evalue="2.30E-243" /identifier="TIGR00170" /label="EJ05DRAFT_447510" /locus_tag="EJ05DRAFT_447510" /protein_end="480" /protein_start="7" /score="805.8" /tool="antismash" /translation="PQTLYDKVFEAHVVNEQEDGTILLYIDRHLVHEVTSPQAFEGLRN AGRKVRRPDCTLATTDHNVPTTPRKNFKGVADFIKEDDSRTQCVTLEDNVKAFGLTYFG LGDKRQGIVHIIGPEQGFTLPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTL LTKRSKNMRVQVDGELAPGVSSKDIILHVIGQIGTAGGTGAVIEFCGSAIRNLSMEARM SICNMSIEGGARAGMVAPDETTFEYLKGRPLAPKVDSAEWKKATAYWSSLKSDEGAEYD LDVFIDSKDIAPTVSWGTSPQDVVPITGKVPSPDDFQDEDKRKACIRALDYMGLEAGTP MQEVVLDKVFIGSCTNARIEDLRAAARIVKGRKVASNIKRAMIVPGSGLVKQQAESEGL DTIFTDAGFEWREAGCSMCLGMNPDILSPKERCASTSNRNFEGRQGAGGRTHLMSPMMA AACAIAGKLADVRKI" PFAM_domain join(38475..38570,38620..38694,38752..39960) /aSDomain="Aconitase" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00330.23" /description="Aconitase family (aconitate hydratase)" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_447510_0106" /evalue="6.60E-163" /label="EJ05DRAFT_447510" /locus_tag="EJ05DRAFT_447510" /protein_end="472" /protein_start="12" /score="543.1" /tool="antismash" /translation="DKVFEAHVVNEQEDGTILLYIDRHLVHEVTSPQAFEGLRNAGRKV RRPDCTLATTDHNVPTTPRKNFKGVADFIKEDDSRTQCVTLEDNVKAFGLTYFGLGDKR QGIVHIIGPEQGFTLPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLLTKRS KNMRVQVDGELAPGVSSKDIILHVIGQIGTAGGTGAVIEFCGSAIRNLSMEARMSICNM SIEGGARAGMVAPDETTFEYLKGRPLAPKVDSAEWKKATAYWSSLKSDEGAEYDLDVFI DSKDIAPTVSWGTSPQDVVPITGKVPSPDDFQDEDKRKACIRALDYMGLEAGTPMQEVV LDKVFIGSCTNARIEDLRAAARIVKGRKVASNIKRAMIVPGSGLVKQQAESEGLDTIFT DAGFEWREAGCSMCLGMNPDILSPKERCASTSNRNFEGRQGAGGRTHLMSPMMAAACAI AG" PFAM_domain 40159..40527 /aSDomain="Aconitase_C" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00694.22" /description="Aconitase C-terminal domain" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_447510_0107" /evalue="5.20E-41" /label="EJ05DRAFT_447510" /locus_tag="EJ05DRAFT_447510" /protein_end="661" /protein_start="538" /score="140.2" /tool="antismash" /translation="MPKFEKLKGIAAPMDVANIDTDAIIPKQFLKTIKRSGLGSALFYS WRFADDGSEKKDFVLNQEPYRNAKVLVSTGKNFGCGSSREHAPWALLDFGITCIIAPSF GDIFFNNTFKNGMLPLRLT" aSDomain 40159..40722 /aSDomain="TIGR00171" /aSTool="tigrfam" /description="leuD: 3-isopropylmalate dehydratase, small subunit" /detection="hmmscan" /domain_id="TIGRFam_EJ05DRAFT_447510_0008" /evalue="1.90E-78" /identifier="TIGR00171" /label="EJ05DRAFT_447510" /locus_tag="EJ05DRAFT_447510" /protein_end="726" /protein_start="538" /score="260.6" /tool="antismash" /translation="MPKFEKLKGIAAPMDVANIDTDAIIPKQFLKTIKRSGLGSALFYS WRFADDGSEKKDFVLNQEPYRNAKVLVSTGKNFGCGSSREHAPWALLDFGITCIIAPSF GDIFFNNTFKNGMLPLRLTPEQGLDAVAAEARAGREIEVDLPGQVIRDADGKQIATFEV EEFRKHCLLNGLDDIGLTFQQDDKI" gene complement(<41520..>42616) /db_xref="GeneID:54488903" /locus_tag="EJ05DRAFT_506698" mRNA complement(join(<41520..42063,42258..>42616)) /db_xref="GeneID:54488903" /locus_tag="EJ05DRAFT_506698" /product="TIP41-domain-containing protein" /transcript_id="XM_033747849.1" CDS complement(join(41520..42063,42258..42616)) /codon_start=1 /db_xref="GeneID:54488903" /db_xref="InterPro:IPR007303" /db_xref="JGIDB:Psehy1_506698" /locus_tag="EJ05DRAFT_506698" /product="TIP41-domain-containing protein" /protein_id="XP_033605510.1" /transl_table=1 /translation="MTTTADTASALSPSPSVSLPPPDTQLPTPQSPAVKSISQHGFTIS TRKLPILKADPIEKLAERLGIAIPEMIFGDNYVRVEHPVSGWAIEFNAGDALDRVDKTD KSMLKVAYSREWQENRQHHSSDIKEVIKPFDWSYTTDYAGSSPSPASPTTRPSPPPTFS TTDTPLPLHLLARRDPILLFDEVPLYEDELADNGISFYTVKLRVMPQRLLILARFFMRL DDVLFRIRDTRVYIEFETGVVIREYCAREEEYSKVREGLRRQGVADARALSVMRDPNEL VQMDLVKVVERKLDGVKVK" PFAM_domain complement(join(41652..42063,42258..42406)) /aSDomain="TIP41" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF04176.16" /db_xref="GO:0043666" /description="TIP41-like family" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_506698_0108" /evalue="2.20E-67" /gene_ontologies="GO:0043666: regulation of phosphoprotein phosphatase activity" /label="EJ05DRAFT_506698" /locus_tag="EJ05DRAFT_506698" /protein_end="257" /protein_start="70" /score="226.0" /tool="antismash" /translation="MIFGDNYVRVEHPVSGWAIEFNAGDALDRVDKTDKSMLKVAYSRE WQENRQHHSSDIKEVIKPFDWSYTTDYAGSSPSPASPTTRPSPPPTFSTTDTPLPLHLL ARRDPILLFDEVPLYEDELADNGISFYTVKLRVMPQRLLILARFFMRLDDVLFRIRDTR VYIEFETGVVIREYCAREEEYSKV" gene <43131..>44425 /db_xref="GeneID:54487014" /locus_tag="EJ05DRAFT_491196" mRNA join(<43131..43238,43289..>44425) /db_xref="GeneID:54487014" /locus_tag="EJ05DRAFT_491196" /product="serine/threonine-protein kinase-like protein" /transcript_id="XM_033745960.1" CDS join(43131..43238,43289..44425) /codon_start=1 /db_xref="GeneID:54487014" /db_xref="InterPro:IPR017442" /db_xref="JGIDB:Psehy1_491196" /gene_functions="biosynthetic-additional (rule-based-clusters) Pkinase" /gene_functions="regulatory (smcogs) SMCOG1030:serine/threonine protein kinase (Score: 225.5; E-value: 1.4e-68)" /gene_kind="regulatory" /locus_tag="EJ05DRAFT_491196" /product="serine/threonine-protein kinase-like protein" /protein_id="XP_033605511.1" /sec_met_domain="Pkinase (E-value: 6.7e-73, bitscore: 241.4, seeds: 54, tool: rule-based-clusters)" /transl_table=1 /translation="MADTRSLEDRFERITVTDENDGGYITQTTTYHHKSKGSLSHAMNL TGLGQPTNPNRMKLPLQRPPTQSQPKSVTTTITKVTTVPTHPPSNPYHDSFASSGVSLS SRSSDEMTVAQVARQSMYNPFPPNKKWHLSMFEIGKPLGKGKFGRVYLAKEKATGFVCA LKVLHKSEISQGKVEKQVRREVEIQSNLCHPNVLKMFGHFHDSKRIFLIIEFAARGELY KHLRAEQRFAEPKAANYIAQMASALKYLHHKHIMHRDIKPENILVGIHGEIKISDFGWS VHAPNNRRNTMCGTLDYLPPEMIKGTDGYSEKVDLWSLGVLTYEFLVGEAPFEDAPMMT HKRIQRCDMTIPSFISSDARDLIRKLLQVDPEKRITLDEIERHPWIVKHVTTSARAYDR GSNSSRGSASSGSES" PFAM_domain 43586..44338 /aSDomain="Pkinase" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF00069.28" /db_xref="GO:0004672" /db_xref="GO:0005524" /db_xref="GO:0006468" /description="Protein kinase domain" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_491196_0109" /evalue="1.50E-71" /gene_ontologies="GO:0004672: protein kinase activity" /gene_ontologies="GO:0005524: ATP binding" /gene_ontologies="GO:0006468: protein phosphorylation" /label="EJ05DRAFT_491196" /locus_tag="EJ05DRAFT_491196" /protein_end="386" /protein_start="135" /score="241.0" /tool="antismash" /translation="FEIGKPLGKGKFGRVYLAKEKATGFVCALKVLHKSEISQGKVEKQ VRREVEIQSNLCHPNVLKMFGHFHDSKRIFLIIEFAARGELYKHLRAEQRFAEPKAANY IAQMASALKYLHHKHIMHRDIKPENILVGIHGEIKISDFGWSVHAPNNRRNTMCGTLDY LPPEMIKGTDGYSEKVDLWSLGVLTYEFLVGEAPFEDAPMMTHKRIQRCDMTIPSFISS DARDLIRKLLQVDPEKRITLDEIERHPWI" gene complement(45362..47126) /db_xref="GeneID:54481135" /locus_tag="EJ05DRAFT_24329" mRNA complement(45362..47126) /db_xref="GeneID:54481135" /locus_tag="EJ05DRAFT_24329" /product="kinase-like protein" /transcript_id="XM_033740081.1" CDS complement(45408..46814) /codon_start=1 /db_xref="GeneID:54481135" /db_xref="InterPro:IPR017442" /db_xref="JGIDB:Psehy1_24329" /gene_functions="biosynthetic-additional (rule-based-clusters) Pkinase" /gene_functions="regulatory (smcogs) SMCOG1030:serine/threonine protein kinase (Score: 92.9; E-value: 3.9e-28)" /gene_kind="regulatory" /locus_tag="EJ05DRAFT_24329" /product="kinase-like protein" /protein_id="XP_033605512.1" /sec_met_domain="Pkinase (E-value: 2.5e-32, bitscore: 108.4, seeds: 54, tool: rule-based-clusters)" /transl_table=1 /translation="MSWGWDAGLDDLKDSTGISSPVIARQSVSAMNGHGDASPRVSIPG VYQYFEYHKYHTNCSPPPDLQPTTYDWDWCDRGSSHVEFTREEKVPLVEGRLLGHGVHG GVYETVVQGKAIAWKRKFTRRQLGDRERKEIDILKKLRHRHIIQLVGTYTKGPIVGLLL YPVATCDLASFMEDVDHLYHEDSDGHDASQYALSRLRISHLLCEDTPNQDSISTRLYNT IGCTASAIAYLHDNKIKHKDLKPANILLGQDGRLWLTDFGTSSDFSTDAESVTEGGERG TPKYFAPEVAAYEGAGRSAEMFSFGCIILEIVGICNGYSLKELEALRPARDRSFHANLD HIVNWFNVIALNSLRDTFLMTDVRMMLRHQPPSRPGIKHLNANLQLLDEIVGPTKLCQT CCAPIHIWSKFGQVKEMEDLTITYGNSYEDRPGETRFKWCFFLWPSNPDVIDKVICFLV SVPQLMFSPS" PFAM_domain complement(45867..46532) /aSDomain="PK_Tyr_Ser-Thr" /aSTool="clusterhmmer" /database="35.0" /db_xref="PF07714.20" /db_xref="GO:0004672" /db_xref="GO:0006468" /description="Protein tyrosine and serine/threonine kinase" /detection="hmmscan" /domain_id="clusterhmmer_EJ05DRAFT_24329_0110" /evalue="8.10E-23" /gene_ontologies="GO:0004672: protein kinase activity" /gene_ontologies="GO:0006468: protein phosphorylation" /label="EJ05DRAFT_24329" /locus_tag="EJ05DRAFT_24329" /protein_end="316" /protein_start="94" /score="81.1" /tool="antismash" /translation="GRLLGHGVHGGVYETVVQGKAIAWKRKFTRRQLGDRERKEIDILK KLRHRHIIQLVGTYTKGPIVGLLLYPVATCDLASFMEDVDHLYHEDSDGHDASQYALSR LRISHLLCEDTPNQDSISTRLYNTIGCTASAIAYLHDNKIKHKDLKPANILLGQDGRLW LTDFGTSSDFSTDAESVTEGGERGTPKYFAPEVAAYEGAGRSAEMFSFGCIILEIVGIC " ORIGIN 1 acaaccaaga gatgtatagt gatggctata gccagggaag gtcaagcata aatggagagt 61 cgcagtacga cgaagacgat gaagaggaag agcattttgc acaaaaggtc gatgtggaag 121 acgatgagcg taaaggcgga atgtatgaca taatggagac agcccgcgag atgtatgacg 181 aaggtgacta tccgacgact tcaatcggcg aagagacgca gactgtgaac gacgcagatc 241 tagtagaacg tacaggttct ccagctctgc agcagccagt ccgacataat ggcccgaaac 301 gtctgccgac gcagaatatg aagctgcaac acactcctac gtggccaccg aatgacgttc 361 cgcccactaa ctggcctgcc gcaaagactc gagttcagac tcacactagt tttgcccaac 421 gcccgaatcc caatgccgtt gctcgaggcc tgcctcctaa taaaaatgta ccagagactg 481 tatctggggt tacgaacgcc ttaacggcca aacaacccag atttatcaag gcggagcatc 541 cactgccaga gtcaaagaga ttgccgaagc ctatagttgt agcttcagca ccgcccccta 601 tgagcccaga tcgtgacatt cgtgagcagg ctgctgaaga gaatatcgac gataccttcg 661 tgatagatta tgccgaacca atcctattca agaagccgta ctctgacttg gcgaaggagt 721 cattcgacca tgatccagcc gagccagtcg taccctttcc agataatctc atgaacgcag 781 ctttgccgga ccggatgcaa tatgcccgac aaaagttcaa ccacgatcaa aagactgcat 841 tcctgtcatc cctcgaactc gaggaatggg aaggtgcagg cgaatggttt gtggaaaaat 901 tcaccgatgc catgaaacaa gtcatcagca atcgaagaga gaagcgtcaa ttagcggcga 961 gattcgaaga cgaaatccga gaccgcgacc gggaagtggc ccggaagagg gcccggactg 1021 aacaggagtt aaactcaatg cgaagtaatg gacagaagct cctgaacacg cctcgtaagg 1081 gtcgctcaac gcctaagaga cagtaatcgt ttacgtaatt tgctcgaggg catgatcatt 1141 tgccaacgcg gtgtggctta caggacacga gacggagttc ggaaaagttc cctatatcat 1201 ctgtgtctct ctactattta tgttcacgtt tcgatccatc agtctagcgc attcgtctgc 1261 agcgatacgc gaacatgcat ttactggcgc attatacccc ctacacgtgt ctgatatatc 1321 aatggcattt catgtatttc gtatggctca tgaacaaata tgatcacatc tcgtacgtct 1381 cactctaccg ctcttaaaga ccttttcgat tcaaccccga gccctcgaat aataaatcct 1441 tctccgctca tcatcacgca tctatccccc ttttccatgc tctcagaacc acccacccat 1501 actcccatac acttcaccta caaacatcag cacccccttt tcgaaatcca tcatcagcac 1561 aggaaaactc accagtaaca tacgcactgc cctcaccccc caacacccac ccaatcaacc 1621 ccgcaatctc ctccgccttg ccaacccgct tcaaactcaa cctctcaacc tcatccctga 1681 tatacaccat catcggcgta tcaacatacc ccggcgcaac aacattcacc cgcactcccc 1741 acgcccccgc ctccatcgcc gcactcttac tcatcccaac aaccgcatgc ttactcgccg 1801 cgtacgccgc actccccgcc cgccccgcta cacccgctat actcgccaca ttcaccacac 1861 accccctctg ccccgcgacc tccatcccct ttccctcccc cggcatcccc acctccgttt 1921 ccctcccaca ccccatcgcc cgcaactgcg cacgcataca attccacacc cccgtcacat 1981 tcacccccgt aatccgcgca tacaacgcat catcaacatc ccagatcggc gtagcaggtg 2041 gattcccccc gttcgtcccc gccgcattga cagcgccgtg cagcgccccg aacttctcca 2101 gcgtggcatc tatccattca ttcacggcgc ttgcgtccct gacgtcgacg acgcggtata 2161 tgagtggtgc gctgtgggtg agggagagcg tggatgcggc ggaggcgagc gcggaggcgg 2221 atatatcggc tagggagagg gatgcgccgt tgcgggcgag gtagtgtgct gttgcgaggc 2281 cgatgccgga tgcggcgcct gtgatggcga ttgttttgcc ggtgaagggg ggtggggttg 2341 acattttgga ttggtggggg gctgtggaga gggagggtgt gaggttagtg ggtttaggag 2401 atggtggaag caggtattag aagggaagga tcaagggatg ggggtgggtg tgtatgtgag 2461 gtatgtgttt cgaggatata tggtgagtgt atggaggcta gcctgaaagg ggtaatatca 2521 ggatgagaat ggatatgtga agcgactgac tgatagtgcg agtgtgaaac aaggggtata 2581 caaatgtgcg atgtatgtgc tgtatcgcca ataatcggca gaggctatga gtgaacaagt 2641 tccttaccga ttgaatgaca gatcacaccg tgctatcgga tcagaggacg gagacctaga 2701 tggagaaaga aagcgtgagc ctatacgaca ggtgcaaact gtgaagatga ataggttcgg 2761 tcagtgttgc atacgtgcct ctgaaatata cgaacctcaa cgaggggaag ctggagctga 2821 taatgcgggg cagaagcaca tgtctagtgg gccagatcca tgtggatgtg ataagtaaga 2881 attcagtcat aatctcgaga acaatacatg ggtatcaaca ccaaaccaca cacactgaac 2941 tccgacgcta ctaataatgc acaaccaacg aagccacata aagagattca ttaagcaatg 3001 accgcatcca ggaaacggtc caacaagctc tcaagggccg cccttcgcag caccatctgt 3061 cctccacccc tcagctgagc gagcccctgc cgggcgatgt catcttcgac cagtgcattg 3121 ttctctctcc agttcttctc cgcttcttct cccgcccgct tcctcagagc ttcctcgtct 3181 tccgtccgat acaagtcaca ccgatcgcac tgcacacagt tggcccctgg tgtgcgccgg 3241 aagtgctgac agaagtgtgc atagccctct gttccgattt tatcgcggca gacgtagcac 3301 atcgtatatc cgcacgtaca gcgcatcttg ttgcagcctg attccttgac aaagttcgta 3361 tggcattgcg ggcatgtacg cttgacggcg tcggccatgg cgcgctcgac agtggtgcgg 3421 agggatgtaa gagccgacga gtgacaggtg tggagtgtgt tcggtggcca ttcggcgctg 3481 caggagaggc acgaagagcg agcgcaggca cgcgatccgc aggtaaagcg gagaccatgt 3541 cgtctacggg caatgcgagt gagtgaagcg gtgaccggag acaataacgg gagtggggtc 3601 gggaggagga ggtagttgag gttgacaaaa aagaatatga agagaaagac gaaacgtagt 3661 atagtggaga gaagattcgc aaggccgaaa agggagattg aaactatcac cggctgaggt 3721 cgaagtgaga gggctaatgg tggctttgag agagcgattg tgtcgacttc ggcgtatgga 3781 cagaatgggc attgtatcag cggtatctgg gacttgatca gagcttcggt ggtgaagcgc 3841 tcattaagct tccgcaggga gtcggtcccc tctttgcccg atgaacgaag agcaatttcg 3901 agggactgcg atgtcaagcg accgcggcat tctgcgttgc tcacagccat gcatctcagg 3961 ctgctatttt caatatcaat gctccgcgac caaccttgtc catacagcgc ttcgtccaca 4021 gtgtgtcgta tgcatcgaaa gcatatgaaa tggccgtctt cattacatgc actgagctgc 4081 tctatcgtag aagatgtaaa gcagcattcg cagtcgtaca tctctccaag ttcttcggct 4141 tgctcttcat tcagcttttc ggccaactcg tggtcgttcg ctacttgttc tgccatttgt 4201 gttgcgatga taggctcgat cagttgctcg tacagttcct tgtccagttc gaagttgttt 4261 gtcgatatca aacgaggtgt cgttggaccg ccagctctgc tctcccggtg ccactctaac 4321 agtggatgat cctcaacacc cggcgatttc ttccgagtga agagtttggt gagtgaatat 4381 cgccaagatt gggtgttcag ccctaacagt gttggacgcg agtgagtata ggaataattg 4441 tgctcggcca gcaccgcatt gatggttgaa cggcttaggt tcttgaactc ttgatagagc 4501 tgcgccttga cagcatcacg atagctttta cttctaaact ggtcttccaa caccaaaggt 4561 gcttctctcg taccctttgc gctcgtgctc ttgtacttat attttcggct aggtgttcct 4621 tcttccttct gctcgtcttc accattgatc gatgacctcc atcggcccgc cacgaacttt 4681 gatttattct tcagcatggc ctcagtaacg acttggagtc ggctctcatc gccaaaagcc 4741 atgagcattt cacgaaatac ctctggctgc acgtctggga agatgtccac cagagctttc 4801 aaagcattgt taagatcacg caggtccagg gcctcatgta agcctttatc tggagcctca 4861 gacggggatg ctgtcagcct ggtgctcgta gggcgctctc tcgttgaccg ccatggcatc 4921 gaggcaaaca tcgtagtcat agtgagggga agcagccttg cgcgagggcc ggcgagtgtg 4981 ccttggacat agtgcgatgg gccaggatca agtagggacg agtcgcgagt gtaggcagac 5041 agtggtagat gcagtgttgg acataacagg acatatatga ggtttagtgc gtgatgctga 5101 tgaatgccgg gcgtggtggg agaacatgaa tatcgtggat caattactcc gggaaggaag 5161 tggatgcaca gccacaatca catgtcaata acgccacact tcttatgctg gataaccgtg 5221 aattgaaaca ctatacctct ggactaatta atcgttgcat tatagattct ctagactctc 5281 aaagtaaagg gatagtcact agctgagtta tagtagagat gagccttagt agaagtccaa 5341 tcaaactaat tgactactag ggtatcgtta gggtttctct gtaacaaatc atagtatgta 5401 ctgtgtggta caaaaaatac gtcatatata tccatacaca tgcatacgta agcagcaggc 5461 ccgatatgtt cgcctccaaa atcgctccct gcaatggatc ttcattacat cccgtcctcg 5521 tccgaccttc tcttcgattg cacctcatct tcccatgaca tgacgcatta gacccctgcg 5581 tgcactctat ttgttgtgtt ccgtgttcgg cgaagctcga caacctcacg tctttagact 5641 tgctatcagt caatgcatcc tgaaacccct acacgaagtc acaggctgct tacaaaagcg 5701 tcaccgagct aggatgttaa tctcacttct atgacatctg tacgcttgat aatccttaag 5761 tttcttgagc agccgcggac tgttcatgta tgtcagatcg tagctgggtc tattacgtcg 5821 gcgatccggg gtacgtgtct gttacctgcg tacatcttct atatgagatt accaagcttt 5881 ctgatagttt tatccactgt tgtagtgttg tgaagccata gtgcgaaacg cagaccgcat 5941 ggagaggcat aagctctcat tcgcatacag acaagtatat agaagacagc taatggtcaa 6001 tgtaattgag gtgcacggag actctgaaac acgcgtacgt ggaagcttct atcaacaagg 6061 tattgactcg agcagctgat tctcgtatga tggacagttg cagctctctg agtcgtgctc 6121 tgactcgcat gaggggacca tatctcgacg tatacgtagt gcttagtagt gtctttgcat 6181 tgctgcggtg tagggtttaa tcagtcaccg gcacgtgtaa acagaccttc gatatgggta 6241 cctcccgtga ccaggttgcg actgcggctc gtggagccgt ctccgtctcg tgccgtaccg 6301 cattgatata gccgctatgg gaggttccct agagcacact accttgacga agtataattt 6361 catttacaca tgaacaagta tactgactct tgtgctcttc actagtcaaa tgttccctca 6421 aagatcctca tgcgaccgtt gtcgccagca aaaggtgcga tgcctcaaga gttgggaacc 6481 atcaacaacc ggtagtggag gcggcggcca tcttaccccg tgcgaccgat gtgcaaaggt 6541 ggatgcacca tgtgtataca gctgtatgtc ttgtgtctcc attacacgag gtctatccac 6601 agtgctagac acacagaact aattactcca atggtagtga ggcagagaaa caaacgatca 6661 aaaggggaag acgtcccatc cccgaaagcg aatacgcagc tcaagcagga tctcccaacg 6721 gtgctatcaa ttccggatgt tgctggatac gatatcaacg acttgatgat gccattgcca 6781 ccgctcgaca tggacatagt ctgtatcgat gatggcgaca cgtacagctg gaataacgga 6841 ccgggcctca catacaacgg cgatgatgac agcatgaccc aagagagctc aggaaccggg 6901 ccaacacttt ctcaagatga aagcaaagat actttaacag agcagctgat gaagttaagt 6961 cagcgagcca cgagggccac acgagagttg gagtgcggag aaattgtttt gccattgaca 7021 gtaaattcac ctgtggtgaa tgaagcattc gagaccgcga atgccttggt gcgcatcatc 7081 aacagtatgc cgctgacgga cagcacgtat gagtcctcat tattgtcccg cgatagcagt 7141 caacaacagc taccaacttt tctggctcta gccgcctatc agtacgtcct cggcctcttt 7201 cgcgcaatct gtggatctat caaatgttcc tcaggatcaa tagcccaggg gattgagctg 7261 cagcaacaga cattgcacgg tgctggctcg tgctccgcgc aattcatcat ggttttgcag 7321 cttatcatgc atctcctcaa tcgcataggt cgtagtcttc gaacagggag ccgaaggaac 7381 tcggaccaac atgagcttgg gggtggagaa gtcggtagcc tacaaggtgt tgtcgattct 7441 gctcaagtca tgcttagaag tatgactgat gaacatgtca agctcggtgg ggtgattcag 7501 gatcttcaag ctgggataga agaaggagtt catatgtaga attaatgtaa agtcggagaa 7561 tatctacaaa tgtcttgaaa ccccgaagcc tcgttgtgca acaatgatct gactaaggat 7621 gcagttgaag agccgattgc atagaatctt tgctttgatc tcataaacta aggtcaacaa 7681 gggcacgagt atcacagact cgtttcttga ccagcatagc ttgccttgat gcgtgatgaa 7741 gacatgcata cagccgtatc tacgatacag ccactcagag gcaactgtcc tacgtatcgc 7801 gagcgatgcg gttcggaatt acttagactc cttcacaggc tagctaactg ccgattcgta 7861 attgaaacac gtctctaaga agccaagtct tcgaatgacc ccttaatcag atatatcaca 7921 ttcgaaccta gacttgatag gcgttcccaa gattgtctaa tgtattagcc gatatcggtt 7981 gagatagctc tgaactaggc atccacaagc ggagccaaaa cttgcttgtg actcgactac 8041 cctggcacat atgctgagtg aggttgaatc tggtaaacat acggatggca ccaagcctat 8101 tggagttaca ctgtggagta tatggactcc ctgcattttc tcaaaacagg gtcagaaaca 8161 gggtcaagaa tcagctgtcg atctatgttc ggttaatcga ctcaggggta gttctggtcc 8221 tgcaagccaa tattggcatg actaagtatc tcacggcttt ggcttgttcg ttcttggcaa 8281 gtctttctat aatattctag actagcttat agggtgcatg aaccagggtc ctggataccc 8341 ggctctgata tggctcaagg aaatatccca gctttgataa gacatccttg tcgataagct 8401 tacaacttgt ctgcaagaca tccgacgtac tatggtacta gaaggaggtc ccactgcggg 8461 cctacccata gtcccttgcg atggatgccg acggccattg ccgctcgtgg agctgcaagg 8521 taatcactta gcgcccctat ctctctatag caagaattta gtatagtatc agccgtctta 8581 tatattcact gtccaatcac atgctggctt gttcaacgcc ttgtttgtgc ttagtcttat 8641 gtatagtgaa catcgatatt tataacgcag gactccgaca gttgtaatca atgattgtac 8701 aaatgtgtgt ttacggtccg tattgtgtac agaccagaca atatcaagta ctgcctcgag 8761 acgggactag tgtcaagtaa tacagcagat ctctatttaa aaatatacac gtttcggcgg 8821 ctactcgcta atctccacta atctatgatc acgagcatgt gtcgtctcgg tgcacttgcc 8881 ggtgctactc aagtactcga gctaagagta caaagggtga tctaatatat ctggacactt 8941 ttaaaacggc tcaggttaca atataagtga tgctgacata tacgacttac cgtttaacgt 9001 tcattctcaa taaatgacta cataaaatcg tttgaaaagc tttcattgtt gaccgtgatg 9061 gtcttaggtc cacttctccg agtcctctct gcctctattc gtgaatgttc ggatttctta 9121 ttacacaagg aatattaact aaattggcga ggccaatctt ctgtctgggg ttcacatcag 9181 agaactttac tttctaacgg gtctactaga atgccaaagt ctgtcgacct caaagtgagg 9241 taaaacatat attctaatgt tgctaagttt cccacagaca cttgtattcc tcacacatcg 9301 aagagaattg tttgcgctaa gaaccattct ataaaactaa gagttcaagt ctaccacctt 9361 cctctataag ctgatttgga cgagcaagca tgaatatgcc tgagaactat gttctgaacc 9421 gtgtctatgc gtccactaac ggaaccacct gcctcttggc acgtacattc ccaacacgta 9481 gatcgtttac gtacgtagga atactcgcca aacctcccgc cctaatttcc aaaggatgat 9541 tcttaatcct gccttcgttc agcaacttgt ctgctaggag gaacagattc aatccaaaag 9601 ctcggtgctc aggggtgcta gggcgtccgt aagtgcccgg aatttcaact ggtgttccca 9661 taattgtagg agccatcaac cagtcggcac ggacatctcg tcgcgtgtat ttgacgatag 9721 ggctaacagc ttcgagcgcg acatatctgc caccagaaga accaatcgcc tcgtagcaca 9781 tccgcatcgt cgatgcgtcg gtcacacagt cgaagacaga gacaaggctg ttcgcggtat 9841 actcgcggat gtcggcgccg catgtagacg agcggtaatc aaagcatgct gcggcaccga 9901 agctctcgca tatggcatta ttggcaggtg aacaggtgac gattggtgta tatccggctc 9961 tgtacatgtt cgagttagtg agataactca gaaataccac ttgcttgtgc aacatatcat 10021 acttgtacat attggaaagg agtaatccac ttacattttg agaagctgag tggccattgt 10081 tccggtacct gttgctcctc ctgataccag cacgaatgaa ggtgtgtctt cggcggattt 10141 tggacgtggc agttcaaggg ctagcccggg tgcttgaaag agagccagtc cagcagtggc 10201 aatgccaaga cccattgagc ttgcctgttc aaaggatatg ttttcgggga cgtggcagct 10261 taagtcctca gtcgccaagg cgtactcggc aaaagcgccc gccgtcttgt ctgaggcgtt 10321 gaggccaaaa gttacggcga ggatccggtc gcctttcttg aaccttgtaa caccttcgcc 10381 gactgaggct acgataccag caaagtcgca gcctcctatt gcgccagggg tattcgaata 10441 gtctacgatc tttgcgtcgt aggggctcag ggcgactgaa cgcacctgac acagaatcat 10501 gcccggcttt ggggtgggga tctcgatatc gtctgcgagt ctgtagccgc cagcctcatc 10561 tccgacgaga gctttcattg ctgtgctagg cttcattgtt gagttgagtt gtgtgttggg 10621 gtttatgcaa agagaatctg atcgaatcgt ctagaaatat cgaaagaaga tgttgctggc 10681 ttatgtgact atgtaatcca agatctgaac aatgatcgca actagggact gctcactata 10741 tctactctgt gcgatcatgt ggggccattt gggccatcat agtcaggaat tccgttcgga 10801 gcgccgaccg gaggtcccac gtcgcctccg aagactgctg agctgatacg gattccggat 10861 agcttccagg ggtcagtgga gaatactctc caactctaac tatctgacgc cccatctgca 10921 actgatctca cgacacagtc acactgacca tactccaact ttcagactta acccatcaaa 10981 ggctcgaaga caagtctatt acacaatggc ctcgaatttc tatcttgaag atacgccggc 11041 agaggtgaag aatgccaagg taagtactag cgagctatag tgtccattag aatctgtatc 11101 cggaattaac caaaagtgct caggggctgc acctaattac ttcgaacact cctaatggaa 11161 agaaagtgca gattatgctt gaggagctaa aggagttgta tggcacggag tgttcgtaga 11221 tctaactcgt ttgtgtctat gtacgaagcc ttgacggacc taatagacac tacgacaata 11281 atcgacctaa gtaccaacga gcagaaaaag gactggttct tgaaacttaa cccaaatggt 11341 acgggagcga tatctatacc tatggatgat acttatctgc gaccgtagga aggatcccag 11401 ttcttattga caacacccaa aatccgcctt tcccagtaat ggagacttcg gcagagctgc 11461 tctatctctt caaggaagaa gacaagaagg ctgcgttcgg ctacaccgat gattatggac 11521 gaagcgaatg cctgcaatgg cttttcttct ggcacggcag cgtattgaag tttctgccgc 11581 cgatatgtcg tttacactaa taaaattctc agggtcaacc aattcaaggg cagttgggct 11641 ggttctcaag aaatgctaag gacaatgagg gtaagtcatc aaaaagtcat tcctaactat 11701 gaagcgtttc tgaccgtcgc tgaacatagt cgctatcaat cgcttcaaga acgaagttct 11761 tcgtatctat ggtgtccttg agctccacct ttcgggtaag tatactggcc aagctaaaga 11821 atatcttgct ggtaaaggcg ctggcaagta ctctgttgca gacatctcga cttggcgtaa 11881 gtgtttgatt cctcaacaag caacgtaatt tgtattgaca catgcaagct tggttagata 11941 gctggcacaa gatggaccag atcactcagg aggacatgga caatttccca cacttgcaga 12001 agtggatcga acgtatcgga cagcggcctg cagtgaaacg aggcacggat cctaagactt 12061 gggcgatatg aatgcgtatg accgtatcaa gatgatctga gataatcaat gtcttgactt 12121 gagtgttagc tgagaccttg aatgaactat gaggagaaat ctatatttgc taaattgaga 12181 atcaacaaat tcctaaataa aattactgcc tccatgcaag aagtagtcgt ccatccatgg 12241 ttgtaccttg tcttcgtcga actttactag aatattcgtt tccctgcatt agcgtctcca 12301 tcaatagccc agcagggcaa tagtagtagg ttcgccgact ttgtagaatc gttctgatgc 12361 aatctatgtt gcatccactt tcgctcatcc tagtgcgtag tcagcttcca tattccctac 12421 cctgcattcg cggcggcagt cggaacttcg gtcggtcaat tatgcaccag atccgatcga 12481 tccgaccgat tgttattttt gtgtcgggcg aactcaaatt agtgtaatca tatcattcgt 12541 tcatcattag agtgcctctt gtggtatcct cgttgtttga cattctcaat cttcaataca 12601 tctttacact aatctgctca catatctgtc tcaatgtctt gtcccgattg cttccttggt 12661 gaggtctcta agggccagcc aactggaaag gaacttgaaa tacatggcgt ccaaacctac 12721 gttactgggc ccgaagctgg tgtcagtccc aaggggatca tagtctacat taccgatgca 12781 ttcggctatg actttgtgaa caatcgagtc ttatgtgacc agtatgctaa aaggggcttt 12841 ctggtctact gtccagactt tatgaacggt ttgtttcaca ccaagacttt tagattacat 12901 ccaacttata gatgctaagg ccgctccatg tctccttcga ttattgctcc tatgcatacc 12961 atcttagaaa agaagtcatg gctctatact atcttcgtca agccattcat acttgtcaag 13021 gtcctctacc acctgatccc ctggtttatg acgtgcagca tcgccaagac ggaggccggc 13081 gtaatcaaat atttcacggc tcttcggacc tcgccgcctc ctttccagac tagagacttg 13141 aagattggcg ctgccggatt ttgctggggt ggaaagcaca ccgtcaccct cgcacaagac 13201 tatccagatc accgcgtcac ccgacactca tcccagagca cctcctcggc ccctgaaccg 13261 cttatcgacg ccgccttctt agtgcaccca accttcatca aggtaccgga ggacattgac 13321 gcaattaaga ttcccatctc ctggtccgtc ggcgaagagg acttgcagat gaagactgat 13381 gatatcaaga aaatgaaagc tattctcgag agcaagcaag acgctgagca cgaagtcata 13441 cttattccgg gtgccaagca tggctatgca gtccgcaccg atcctgagga taaagttcaa 13501 atggcagcag cggagcaggc ggagcagcag gctgtgtcgt ggttctcgcg gcgcttcact 13561 cgtacacctc gtaccgatgc ttctcccgtc gtacagcgac ctgcccagga tcattcagcg 13621 agcctttctt cggaatcttg aatataaatc gtggcaactt gcccaaagat tgaccggtcg 13681 gtggtgattg aaggatatca tctgtgtgga cttgtttacc acttcaatcc gagcgtaacc 13741 gaacaagaag actcatgagg tgataattaa agagttcatg aagcgtagta tatgcacaag 13801 agttcctcgt atgcagtgct tcttgtaata acgtgaagga ttttgatgtt ataaccttgg 13861 aatggcttga gtagaatgcg aactttactg tagaacagga aactaggagg gcgcagctat 13921 taacgtcact gacaacagcc agaggattat aatttagggt cttagttctg tccaaatctt 13981 atttgcgacg cgttgtttaa tctaactagg cgttcgaatc tactcatgtc gctttggagc 14041 ggagctcaac tcggttgatt gttcccaaag tcgaccatca gttcacacat ttgtggcatt 14101 tttgcatgat ctttcaatac gttgttagat gtggtggtaa agtgaatgaa tctcatcaac 14161 tacggcgtta tcgtatgcat agtactcaga tatacagcga gtatctcaag actcggggac 14221 cgaaccacct gccacgctct ccatcgtgct tataagcaag tatcctccga ccagctgagc 14281 caacgcagca acaccctctt tacccagcaa tgcaacagcg gaatcaaact gtttgtcttt 14341 gatattacca aagcctcttg caacgctcaa cgctagctcg tagacgcatt cctctctgtc 14401 cgataggccc tttggaagat gccctgcgct ggctcgttcg acttggtcct gggtcaagcc 14461 taatgatatt ccaattttct ggtgagcgta ctcgacgtag tcactcttgg tgacagaaac 14521 agtcgccaac gtggtcaatt cgcgctcctt gggggtgagg tgcggcagag tgtaatagga 14581 ttttgagtag ctgaggaacg gcttgaaggt tgatggagtg taacaaagaa ctccgaaagg 14641 gccgaggaag tttccctgag cgtctttgaa tgagaaactc tctccttgga gctctttgac 14701 gtcacgctct gtttgctcga aagcctcttt ctgttcctgg ctcccaaaga cggaggggaa 14761 acggggagct ttggcaacca ttctggattc gttgcgaatt gaaaattcgt gtgaggaaat 14821 agctgacacg gaagactggt atctagaaaa ataatgagac aatttgaatg cagattttgg 14881 gacccaacgt gtaaccgggc gagggacaag cgtggcgacg tatttaatca tggacagcta 14941 agcattgtag atgggacgta gtcttacgac cgattgcgaa cctccgtgat ttgtaccgga 15001 agctccaact cggtagcaca actcggtagc agactgctac cgactcgcaa tatcggcagt 15061 cgggtcagct atgggcagcg gagtggaacc tccgacatca agatcttaga tcagtctcac 15121 tatgcgatgc tagctaaaaa caaagagcag cgccagctct ttcttgttca acaaaagaca 15181 aacaaacaat ggcacctact cgcgaagaca ttgagttcaa gacccttgcc ggcatcacct 15241 tgcgtggatg gctgtaccca gccgaaaaac gtggaccagg aatcatcctt tctgcagggg 15301 tatgtaaatc accacgtctg aattttgaag aagactccaa agccgactaa tttcgataca 15361 gttcaatatg cctaaggatg tagtcgtacc agatattgcc gaatggtatc acaagcgagg 15421 tttcactgca ctcatctttg acacatatgg catcggtgcg agtgatggtc tacccagaca 15481 tgacgtgagt tattctttgc aacacgaagc cagccaatta gatgtcaact gacatgcaat 15541 cgtggtggta gagtgatatg ctgaggcgca ttgacgactt caccgactca gtgacgtggc 15601 tctcccagca tccccttata gatccggaga aaatcgcagt ttggggtctc tgttttgacg 15661 gcaacattat gcttgccacc gcggcatacg accgtcggat tgctgccgta gtaacggttg 15721 ccccgatgat cgatgttact ggtgaccccg aacgccgcga agccattttc gaacttggac 15781 tggcagaccg cgctgcccaa cttgctgggg aggatcccat gtacctacct ctggttgatg 15841 aagacggcat gacgccactt ggtcaattct taggcaattt cttcacaaca atggatagca 15901 tgaaaatgcc cattgagaac cgtgtcacgg tccataccta tatgcgatgc ctcaactgga 15961 acattctaca cctactgcca aagatcagcc cgaccccagt gatcatggtg acgcctgagc 16021 tcgaccaagt attcccggca agcaggcaga aggaagcatt tgacttgttg aatgagccga 16081 aggaacattg tcttctggtt ggaaagcatc actttgactg gatgtttgga gatatggaca 16141 atgcgttcag tccgcaatat gagttcttga agaagcatct gaggctttag atttattgga 16201 tagattagga acgaaataga tatactcatt ctacctgtga ctatatcata cagtgtcctg 16261 tgacgttcta gccgaattat ctattgctca gttcatgtaa tgtatgttgc tacaacccca 16321 aagattcagc tgagcatctg agctacaata cacggacact acatagcagt ccacttctca 16381 aattcgacta atgcaggaaa tactattatc ttgactttga acctgagtgg atacgttata 16441 actctgccag acacgcttat gcgctaagaa aacagccact agaaagttat caggagacga 16501 gagtgtaagc tcggcttact gtatttgcac cgggccaccg actcgggagc cggggcatag 16561 cagatccttg tcgcagtgag gtcactcaaa aaagctccga tagttgcatt taaaatccac 16621 cgtaagccgt tttaagaacc accgagtatc aagttgcttc tacatagtac tctttataag 16681 tttcaatacc tgagcctaca gccctgcatt atggtctcct cagtgatccc tgaatcaata 16741 tccattatcg gcgccagcgt gggcggactc acgcttggta tcgtcctcaa gaaatatggc 16801 attcaaccaa ggatcttcga atcacgagag ccaggctacg atttcggtgg tgccgtctcg 16861 cttactccca gcactttacg tatcatcgac tccattggtg catactctcg catcaaacct 16921 caaggcttca gtttcgaggc catgacattc ttgacggatc ctgagcgcga gactactggt 16981 aaattctact ttggacacaa agacgtgtac gggtacgatg gtctgcgcat cacgaggaag 17041 gcgttgctcc acgaattgac ggaaatggca aacgatgctg gcgtcgaaat caactatgga 17101 aaaaagttta ccaagattgt caatgaaacg accgatggtg tcatattcga attcgcagat 17161 gggagtcagg agaaagctca aatgttaatt ggctccgacg gcatccattc gaaagtcaga 17221 tcatgtatct tcccagacat ccatccacat tactctgggt ttataggcct gacgtactgc 17281 ttcccccgcg ataatgtacg catcgatgag ggtttcccac tcccagtatc tttgcgtggg 17341 agccaaggtg atggcgctat catgctacaa cctcaaacag aaggtggaaa agagattttt 17401 gtaggacggc agttcaagtt cgaagaaaaa gatcgctcag gatgggacag tctcttgcag 17461 gaaaaaaaaa ctttgattgc aacccttcag cgagattctg ccgcatggac accacttatc 17521 cagaacgtgc tagcacaagc gagcactcca gaggcacatt ttctgaacgt ctggccattt 17581 tatactgttc caaaaatgga gagatggcat tcgtcagctg gaaaagtgct tattattgga 17641 gatgcagcac atgctatacc accttcagca ggacaaggcg caaaccaagc ctttgaagat 17701 ggttacagcc tcgcaatatt cctagcaagt ctaaagaatg tccgcgtaag cttgttggat 17761 gcgttgaaga cttgggaagc ctataggatg aagagagttg atgatgtatt gaaaataact 17821 aatcgacttc tcacaataag gatgacagag gaggaactgg cgagtgttcc aaagcacatg 17881 cagtgggaac tcgatggcag tgaagcgggc aagtcgcagc tagggtggct ataccttgca 17941 gatatcgatc gcgatatcaa gagtctagta gaaagtctgc atatgtaata gtgaccgggc 18001 aatgtatagg ttatcataac agacagggtc attcggaaac ataggtatcc atgcacttct 18061 ccagtacctc tcaataaccc aagaggattg cttcctcagt cttacaaact tcgcattcaa 18121 cagcatggtt acgtttctct tcaaactttt atgacaggaa gatcccatca ggatatatag 18181 tatggggatt gcattataaa tgattgtgta tatacgtcaa aggaatgaca ctgtggaaag 18241 tatatgcgca tgcttacata cattccaata cccagcctgg gtcgacagat gtgcatgaga 18301 atttgagaga agcatttcgt accttagaag cctagaacat ccttaaggaa cgctagctgt 18361 ccggtcagaa gctcatcaat gtcaacgctc aaaaagtttg cgtgacccct atctttgaca 18421 atttggaatc ttttctgtgg tgattgcaaa ctgtcgtata tgctcttctg atactcagga 18481 ggcacaatct catcattctc aggtgtcaaa atcatgaccg gggtggggct gacagatgca 18541 aataggtgta tgggcttcca cttcgcatgg cgatagaagc tctgaattgt gagactgtct 18601 ctgaaggtcg aggcagcctt cttggctccg acgatccagt tgggaaggtg agcctgttgc 18661 tcaggcgtca ttttggctag gtaattgaag agcaggaagt gctcgccctt ttcattgaga 18721 aggggcatat acgccggcgg ttcgcctcga agctggtttg ctcggtcctc aactgctcgg 18781 gcaacgaggt cctcctgatc cttaggatcc aggtaccact caggcatgag gccttgcgct 18841 atgacagctt ttatgcgcct atcgaatgct gcagcctcaa gtgctattcc agaactgtag 18901 aagaatcccc atacggctat gcggtttggg tcaacccagc cgtcgttctg caaaaactgt 18961 tttctattgt ttagtgtatt gtttatagag caaccgaagt cgcattgata ggtagataca 19021 taccgtgacg gcgtcagagt tgtcttcggc catcttttgt gggtccaaat cggttcgggg 19081 catgccatcg ctcgcgccaa tagaacgagc atcgtaaaca agagctgtca gcccatgacg 19141 tccgaaccaa gccgctatat tagccacgaa gatttctctt gggcacataa actattgtat 19201 agaatatgac taggtaagca aaagtaccaa ctaatattct tgatagatta tgaggcgttt 19261 gtccatcaag gaaaacttac agcaccgtta acaatcactg caggaccgcc cttggggccc 19321 acgaacagcc aaccacgcaa agtcaagcca tcgaaggtct tgaactcgac atctctgcgt 19381 tcttgctctg cagccatgat gatataggat tcagaaaagc ttagtctcgt gtcgagtact 19441 tcagtagaag agcaatgtgc gccaccctgc caggagaaaa cctagtcgtt aggcttcgag 19501 aactcagtcg agattgccga tcgagctttc taagaaagac aaagaacttc gacgttagat 19561 taatgttatt attgttctga gtcggtagag gaacagtcct ccgaaaggat cggagtatcg 19621 gagctaggtc gagtctccag gggcacagga gaccggtggg tcgcttactt ttccggtccg 19681 gtccggtccg gcgctatctg gacgaccgta ccggttcctg cccgacgtga tactacagct 19741 ccgaaagcgt tcgctgtgtc tgaggctcgg atagcgcatt atctcacctc ttcaaaactg 19801 aataaatatg tccaacaacg acctgcacgg tatctctgac gcggcttgca ttcccacatc 19861 actacttcgt atgcccagcc accgtcacgt ccaaaacaca caaagcgtga agcctccatg 19921 atattgagct gctatactct cagatcgatt cagccaacca cttttcatag ttcaattgat 19981 cctgcagcac aatattaatc atgggcagct atcctcagtc taacgatggc ccacttcgag 20041 agcccattgc aatcgtggga agctcttgtc gcttcccagg tggtgctact tccccatcaa 20101 agctatggga tctcctctca gatccccgag atcttgtgca agagattccc gccagtcgct 20161 ttgatccgaa ggttttctat catgaaaaca gtcagcacca tggagtatgt cccgttggct 20221 atctcaagaa acatatctga gttcattggc taactggtgt aacaacagag tatgaacaca 20281 aaatatgctt atattttaca agatgaaccg cgacttttcg accgcgattt ctttaacatc 20341 agcccaaagg aggctgaagc gatggatcca cagcagcgat gtcttctgga gactgtctac 20401 gagggagtgg agtcggcagg ttactccatc cctcagctcc aagggtcttc tactggtgtc 20461 ttcgtcggag caacatgctt cgactaccag tccattgcaa tgcgtggcct cgatagcctg 20521 ccgcagtact acgccactgg cgggtccatg gcgatcctag ccaaccgtct atcgtacttt 20581 tttgactgga gaggtccgtc acttgcctgc gatactgctt gttcgtcatc actcgtggcg 20641 ctgcaccagg cagtgctttc tcttcgaagc ggggaaatca acatggctgt tgcagcgggg 20701 gcaaacctca tcctcgggcc agaacttttt atcgcttatt cgaatgtatg ttgtgccatt 20761 aatgagcatt cttgggcagt ctcagctaac atatgacatg atagttaaat atgttgtctc 20821 ccaatggtcg atcctacatg tgggattcat ctgccgacgg atacgtacga ggagaggggt 20881 tcgcctctgt cattctcaag acccttagcc aagctgttgc tgatggtgac cacattgagt 20941 gtattatccg tgaaaccggt gtaaactctg atggtcgaac tccaggtttg taagccacgc 21001 tgttcataat gacggttgaa ttaaccgtca tataggtatc acaatgccaa gtgcagaggc 21061 gcagtcccaa cttattcgag acacatataa gagatgtggg ctggatccgg tgcgtaatcg 21121 tcctcattat tttgaggctc acggcactgg tactccagca ggcgatcgta agtatacgat 21181 catcacaaca aagggatctc gatgctaaat tccaccagct attgaggcac gtgccataca 21241 tgatactttt ttcccaggac atccaggcca gaatgacggt cacctctttg taggctcatt 21301 gaagaccatc atcggacata cagagggcac tgctggcctc gctggagtac tcaaagcatc 21361 gttggctgtt caacacggcc agatcccggg caaccttcat ttcaaagagc tgaacccgaa 21421 gatccagcca ttttataagc atctaagggt tccaacagga ttgacttcgt ggcccactct 21481 gcccaaaggg gagccacgcc gtgtaagtgt caacagtgta agtcttgacc tgcatccaaa 21541 tcgcaattga atcctaatct gaggcagttc ggctttggcg gaaccaacgc ccacgctatc 21601 attgagagct gggatggagc atacgaccgc tatgcatcct tgtcgaatcc gggcggactt 21661 gttgtcctgt ctgccaactc ggctcaagca cttgcagcta aagctacgac gctggccgaa 21721 tacctacgga aacatcctgc tacagatctt gggcgactag cccggaccct attccagaga 21781 ggagacttcc tcttccgagc ctcatttgcc gctgtatctg ctgagcagct tgccggaaag 21841 cttgaatcgc gcgcagaggc gctcaagaag actgcacgga ttccagccat tccaaagtcc 21901 ctaccgcctc gtatccttgg tgtctttaca ggtcaaggtg cccagtgggc caccatgggc 21961 aaagaactct acgaagcatc atctgtgttc aggaagacgt tggaccagct acagaacagt 22021 ctcgatacac tccctgagag cgatcgacca aactggaagc taatcgacga actctctgct 22081 ccaagggaaa catcccgcgt tggtgtagct gccatctcgc agccgatctg cacagccctt 22141 caagtcgctc tagtagacgt tatccgcgca gctggagttg actttgcggc cgttgtcgga 22201 cactcaagtg gagaaatagc tgcatcgtat tgtgcaggct atcttgacgc tcgggatgct 22261 atacgcgttg catattacag aggtttccat tctaatctag cccaatgcga tggcaagcgt 22321 ggcaagatga tggccgtggg catgggcttg gacgccgcgt tagcattctg tgctgaattt 22381 ggcacaaacc tcaaggtagc agccaataac tccaccacta gctgtacgct ggctggtgat 22441 gccaacttga ttgacgaggc caaggctcaa ttggacgagg acaaagtctt cgcccgtgtc 22501 ttggcagtgg acacagcata tcactctcat cacatgttgc catgcgcggg tccttacctt 22561 gagtcgttac gacaatgtgg agtcaaaact ctgaaaggcc ccagaaagtg cgagtggtat 22621 tctagtgttt ggggatcaaa tggccgtagt cgttctttca acgacgagaa gggcatggaa 22681 ctgctcgaag gccagtactg ggtcgataac ttgaccaaca cggtcctgtt ctcccaggca 22741 gtgaaccgag ctgtgtctga agaatcctca gtgttggact tggcactaga ggtaggcccg 22801 catccagctc tcaaggggcc aagttccgaa gtgatcaagt ctttgaccgg cctgaacctt 22861 ccttacagcg gtgtcctcaa acgcggagaa agtgctgttg aagcttttac cgatagctta 22921 ggacttatat ggtcctcttt cccctcgtcg cgtcctctca tcacttttga tggcatatta 22981 cgggccttgc cgctggctag tcctaagaaa cccagcattc tcaagggcct accaacctat 23041 ccttgggatc atgataccct taattggcgg gagtcgagag catcgcgtct cttccgtggt 23101 ggtcagccgc cccacgagct gctcggtcga ccaacgatac ttggtgaaca agctaggcga 23161 gaggtctatt ggcgccaggt tttcaaactg aacgagctcc catgggtacg aggccatacc 23221 atacaaggcg aagtcctctt cccagcaact ggatacttga caatggcgta cgaggcagca 23281 gtgcgtctcg tcgatgacca ggagtcaatc cgtcttgttg agctccatga tatcgagatc 23341 gtgcgaacca tgggcatgca ggaagactcg tcaggcctgg aggttctatt cactgtccgc 23401 gtgacgggtc agaccgacag ctgcattact gccgaagtgg cctgttacag cggcgacatt 23461 accacggcca agttggacgg ccctgtgagc tcgctcaccg cacatttcag tggtggtgtg 23521 cggcttttgc tgggtccagc ccagagcggc gaccttccca cccggaagaa gcctctactc 23581 ccaatgaaca ctttggatat ggaccaattc tacggttatc tgtcgaaagt gggctacaac 23641 tattccgact ctttcaaagc gcactcggtt gatcgtcacc tcaaccatgc cgtggtatct 23701 gtctcgacac ctgctgaatc tgcctcaaca tgtccctcaa tgcaccctgc agttctcgac 23761 accgctatcc aaggcctcct ggccgctttt tcatacccag aagacggaag gcttgggaca 23821 gtgtatctcc ctacgggcat tgatagtgtc cgcatcaaag tggcatctga ctctcccgac 23881 gtcttgatgg cagacagcgc tttgacttcc tcaggggaga aggggctcac gggtgaagta 23941 gaccttttca acgcaagcga ttcaactgtc caagtccaaa tgcgaggagt gagctggacc 24001 gccctaaatc aaggccggga gcgctggcta tatgcaagcg aggaatgggt acgagacgca 24061 tctcacggca tcgagcctac cctgaagacc aagttctctc ccgaagatga agtgttgcgg 24121 aagctcctgg tacgagtagc gcatttctac ttacgcgccc ttcgcagcca gataaagcct 24181 tcagaactga tcgttatggg caaacatcgt cgtcacatga tgagatgggt ccgtgagcac 24241 ctgtttcccc agatcgaggc aggcaaggtg cccgatattg agcctgagtg ggcgaatgat 24301 acgcttgaag aagtgcagca atggagcgct ccctatattg aagcaggaaa caacgacatg 24361 ctcatcctgc acgctgtagg caaaaacttg cctgctattg ctcgcggaac tatgcctgcc 24421 ctccaggtta tgcttaagga cggcatgctc gaccgtttgt atgtggaggg agtcggtttt 24481 gccgacggta accttgatct cgggccgttg gtcaagcaag ttgcgcatcg atatccccgg 24541 atgaaggtcc tcgaggtcgg agctggaacg ggtggtacca ctcgcagtgt acttgagtct 24601 gtcggcgacc attatggatc atacacgtac actgacatct cagccggctt ctttgagccg 24661 gcaaaggcaa agtttagcga gcacacaagc aaattgacgt tcaagatgct gaacattgag 24721 aaagatccga tagagcaagg gttcgttgaa ggctcatatg acatggtcgt agcctccaac 24781 gcgctgcatg cgactcgatg cttgaaagat acgctcagcc actgtcgcca gctgcttcga 24841 cctggcggat acttggtatt gctagagatc acgaccaacc atctgccaat tcaactcatc 24901 atgggcacgc ttcctggatg gttcctgggc gctgacgaag gccgcgtctg ggtgcctacg 24961 cttagtcttg aggaatggga caagatactc aaagagactg gattctcagg tgttgacaca 25021 agctcaacac cgtccttctg ttccgtcatc atgtctcggg caactaccga gaccttcgaa 25081 gccattcgag agccactatt aactgcaccg cgcccagcag cccagccact gggtcctgtt 25141 cttattgtca gcaatgcggc gtcagaactt gcatccgggt cacaagccct cctcacttcc 25201 atcgagggtg ttactcaatg cgatattaca ggcctcgagg acatcaagtg ccccgtcgga 25261 gcagtagtgt tgtgcctctc tgacctggat agtccagtct tcgaggaaat gactgaagcg 25321 agattcgaag ctatgcagac agtcttccgc aatgccagcg tcgttttgtg ggtgacgtca 25381 ggggcaacct cgggcaagaa cccgctggcc aatgtgacag taggattggg acgtacactg 25441 ctggccgaac gtagtgactt gcagcttcag ttcctcgacg ttgatgatcc aacatctctg 25501 gagccgtctc tactggcgaa gcttctgctc agactcaccg gaacagatca agctgatcta 25561 agcgagatgc tctggaccca agagcctctt cttgcactta aagatggcgc gttctatatt 25621 cccagggttt tgcctctaca agttaccagt cgtcagtcta caacggagcc atccgtcgaa 25681 gtggcaacac aagattcggt agagaacgtc gtcaccgaaa ccggccttga tgagcataaa 25741 agcactttcg ccgataacaa gacctacatc ctttttggca tgacaggaga tcttggaatc 25801 tctattgctc gatggatggt ggagaacggt gctcgaaacg tcgtgctgac cagccgccat 25861 cccgatgttc cggagggagt gttcgaattt atgtcacaaa agggagccat actgcgtgcc 25921 atatcagcag atgttacgga caaagaagga ttgaacaagg tatacgcaga gatcaagtcg 25981 actttgccac ccattggagg tatcatcaat ggcgccatgg tactccgaga ccgccccttt 26041 gtcgacacta cctgggacga ctttgaggca gtacttgcgc caaaggttgc agggactcgc 26101 aaccttgatg agctctttgg tgaatctgag gccctggact tcttcattgt gctttcgtct 26161 gcgacatcca ttgtgggcaa cattggacag tcagcttata gtgcagcaaa ccattatatg 26221 acaagtctcg tcaaacgtcg gcagggtcgt ggactggttg ggtcagtcgt agtcattggc 26281 ttcctgacgg gcctgggcta catcttccgt tcagacaaga agcatcgcgc tgccattgag 26341 aagtctctcc ttccacggct ggatcgacaa gccgagacag atctgcacga tatgctcatc 26401 aaggctatcg agtgcggacg accagaatcc aacctaccat ccgagctcat cactggtata 26461 aggaagaagt tcacagaagc gtggcacgaa gatgtgcgcc tatcaggcta cctcctacaa 26521 gaaggtgaca aggaggaagg cgccagtcag gagcaagctg atgggaatgt caaagttgat 26581 attcagctgg ctgcaaccaa ggatccaaag gaaggtctcg caatcctgat caagtgcttc 26641 tcgcaagctc tgggtaacat gctccagctc gatccggccc agatcaacgc cgatatgcct 26701 gtggctgaac atggtgttga ctcgctcgta tccgttcgta tacgtgagtg gttcctgaaa 26761 gagctcggtg ttgacgtgcc ggtattgaaa ctcatgtcga ccaaccacac catgtcgcgc 26821 gtatgcgagg atgccttcgc aggatggcga aagcttcgct cagggtctca ggcagagtcc 26881 cagaccgcta ccaagaccca tgacgatcca gaaatggatt ggaagaagga agtagccggg 26941 ctcatcgacg gcattcctgc cctggtcgca gctggcgttg actccgccga cgtgcctcgc 27001 actagcgcac gccgcgtcgt cttgactgga tgcacaggtt tcttgggtac gcacatactt 27061 cgtaacctcg tcgcagaccc caataccgca gaggtgcact gtctctgcct tcgctcgcgt 27121 cctctgcgcg tcaaggacgc aaggatccac gagtacaagg gcgacctagt caaaccgttc 27181 ctggggctgt ccgcggccga cttcaagcgc ctcagccaga cggccgacct aatcatccac 27241 gtcggagccg acgtcgcgca tctgaaatcg tacgaaatga tgcgagctgc caatgtcatc 27301 tcgacgcaga cgctgctcgc gatggcgacg ccacgccacg tgcccgtaca ctttgtgtct 27361 tcgtcgtccg tggcaatgtt gcagaaggat acagcagagc tgtgggaggt gccgccgtcc 27421 agcttctggc caccgtcgga tgcagagtcg ctaatgaaga atgcgattgg ttatgcagcc 27481 agcaagtgga tgggcgagat cctgctggag cgtgcggagg gtgttccggg cgtagtccat 27541 cgcttcccca acatcatggg gccggacgca cccgaagaga tcccgctagt ggccctagac 27601 cgctactgca tgaagctgcg ggccgtccct gcgctagatc ccaagcagtg ggtcggagag 27661 cttgacgtca tcgaggttac tgacgtggtg ccggaactca tggccacggc gtatgcccat 27721 gatcccagca agtcattcgc aattcacaac tactgcagcg agaatagata cttgctctcg 27781 gatctcgtga gtatgtacaa gcagaagctg ggtggcaccg ttgaagtcct gccgacacct 27841 gagtggatgc ggagggctaa ggacttgggc atgcccaagg gagtggaggc tacttggact 27901 gggcacaatg aagtgttcat atcgcctgta ttgcacaaag gacaaaaatg attagacata 27961 gagtatagag gcgactgtaa attgtataga ggcgactata aattatataa aggcgactgt 28021 aaattgtata gatgacagta gaatattaga acgctctctc ctcattgcac ttcattccaa 28081 cgttggattc tgttaatagg atttacaaaa tacgatagaa aacagagatg taataatact 28141 gtataataca gctcttttct tatcgacatg ctcgttcatg gaaatcatct ctctttagta 28201 ttcgctaaca acctacagtt tcataaagag tagatgaaac tttttccttc tacatattta 28261 gagatacaaa aacttcataa cataatatat tatgggttct aagacgatcg aagacctata 28321 atatatagaa tatagcatta catttcatgg tgatgcacgt ttgtatagaa agtaatccag 28381 attgagctcc ggtgtttata tatatataca tcattttatc ctaagagaga agttatccca 28441 aaaggcctga agtcgcaggt cgtcatggca actagagcta tgaacgtgca aatgcggggc 28501 acatggattc tagccagacg agttcaaaaa ccctcacccg acctcaatct caatcgcatc 28561 acctcgtctg tccaccaacc catcgtcgaa gcacctccga aaaatcaata aagctttcat 28621 atttcaattt caatgctaat gctacaaagt gaactacctt gcgaggtcta cttgagtata 28681 ttaagaaaag ctagccatga gcggcaccca ttttccaccc ctctaacacg cattctacgc 28741 tctcctctac cccaaaccca atgctaaaat catcgtacac atgaaatgaa cttcccgcct 28801 cgatcagtca acagcaccgc ccttctcgcc cctatgttgg gggaaatagc catctcaagc 28861 cttgctagca gcctgcttct ttgcattgac attattccac ctggtgagca tgctgacagg 28921 cacacagata ccacagcacg cgattgtgat tgcaaaggca accttgatac cccatgcata 28981 cgcgcgcaag acgccgtcga ggtcggcgcc ggtaaagacg cggtgcagat ccgtggcgcc 29041 ggtggcggtg acgagggttg catcgagatt gggtgcggtg ctggcgagct ttgcgacgag 29101 ttggttgacg aagccgcact gggcggctga gaggaggatt gtaccaccca tggatcgaca 29161 ccctgggaga agaaattagt aaaagaggca gaaagggggt aagtaggagt gatggcatgc 29221 tcgatctggt cgaaggagac ttacatatga tgattgccgt ggtgggggct atatcagcgg 29281 gtgcggagaa ggcctgcgag atgatgacgg gaacttgcag cgcgagaccg tatccaaagc 29341 cgcctaggat ctggtagcca acccatttgc ctgtcgatgt tccaatgtcc atggtgaaga 29401 atagaccggc ggcgatggtg acgattacgg agctaactgg caagtaagga gctgcgacac 29461 ctgtctttgt gatgatcaca cccgagccgt atgtggcgat gccgaacagg acgatgagag 29521 ggatgttgcg gacacccgag ccaatcggac tggcgttgtc gatactttgg aaataaatgg 29581 gcaggtagta gagcgtgacg aaataagcgc cggcaaagaa gaaaccccaa agaccgttga 29641 cccagacgtg tcgttgacgc atcaggcgag gtgttagcat ggcgcgttcg ccctgccaga 29701 tctctactgc tgtgaggact ccaacgatgg caacgaaacc gacgatcaat ccgataacaa 29761 gactagagct ccacggatgg gtctgacctc catactgaag ggctagtagc aaggtgaggg 29821 atgcacccat ggtgagcgtt gcgcccaaga agtccatttg caaaagcttc tcctttaatg 29881 tagcttggac caccttggca gctgcaggag tcttgaaggt gaccaaaatg acagcagcgg 29941 ccagaccacc gattggaaga ttgatataga agcacctaaa gttggtatgt cagacgaggc 30001 cattgcagga gcggaaacta tggaatagtg caacaaggaa aaagtagtaa gtaaaacgtt 30061 gactactcac catctccacg acgctccatc agtgagtcct ccaccaatga gtggtccaca 30121 cacagcagca acaccatacg aaactccaat gaccgaggtg taggtagctc gtttcgtggg 30181 ctcagccgca aacgccgaaa tcgtgtaaac tccaggcgca atacccgaag caccaagacc 30241 ggaaatagca cgtccaacga tcagagtcat tgagttctga gcgactccgc tgatcaagct 30301 tccgagttcg aagatgaaga ttgcgaccag gaagctggtt ttcagtggga agaatttgta 30361 caccttgccc catagtgact ggaacgcgcc aagcgtcaag aagtaagcag aaccgtacca 30421 cgagatatca tcaagcttgt ggaattggtc cgtgatcttt ggaattgcgg tcgcgacgat 30481 ggtctgcatc gagagtgtta gtttattagc ttgatatacc acagcgaaga cgactctgga 30541 agggcgatat gaagcagaac tcacctggtc cagagagatc agtgtgatac tgagtatgag 30601 agcaagcata atgaacaaga cctcgatacc ctttgggtat gtcataggtt tcggcggctc 30661 agcgacaggt ttctcttcgg tagtagcacc atcagcttca ggggcatctg atctgggtac 30721 accattgtcc gtcgaggagg ccgaagagga catttcgttc ggcttttcct tctcaggatc 30781 gacctggtgt gtattgtctc ccatatctgc gagcgtcctg tcctctggca agcgaggcgg 30841 tggtgttgaa ggggacatat ctgtttgaag gatggtaaga gtctgtgtac tttggaaccg 30901 cagcctcgaa ggattcagag tgtgatgtag aaagtagaaa agagaaatgt aaaatatgac 30961 caaatatcag tcaaagttgg cttttgacta gcggacatga ggatttagta ctaaaggcgg 31021 gtaaggcctt taacgccgtt cattcactcc cctgtcaaac ccctactagc gttagatgcc 31081 ggagctagat ggatctgata gaaggtcgta aatccgctaa caccgttcgt acttacagtg 31141 gatacagtaa gattccgttc actcaccgac cgattcgtgc ttcggagatc atatgcaagt 31201 aagctcttcc gtcaccgtac acgaatcagg taatcgcgag tgaccaaaca agctccttcg 31261 tcttgccttt tgaccttgca acttactgta atagttcgca ttctacatac aaccaactca 31321 aggcaaaaaa aaggctatat tcatagttat gcgcatccat atacaacagc agacctagat 31381 gaaggacgtc agagtgtact gtgggttcac gagtcagtca tgatacagcg gcacacgtgc 31441 cttgactcat gcgcgccaat gacatccatg atcgaccaca tatacccaca tatacatggt 31501 gagcctcgac gcggagtgtc gtcagaaaac aggataagaa attccgacat gttgcttggc 31561 gcggtccgat caagccaagg attttaagat ttgccctttc tgtgcggcgt ggcccgactc 31621 cctaggctta ctttcttata tggcgtagat gtctgcgact ccgtgtgatt aaatgccttc 31681 attgcttcca agatgcttaa cgtggcgtga tgcattaccc ttatcggagc gatcatttct 31741 tgacagaagt cttgtgcgtg tcttggtcgg cggctgattc tcctaactcg actcactcag 31801 cgaccacgag atgcgttcat tcacaggatt catcttcaat ggtcgagtgt tataccgaat 31861 ttgcatgatg gaagcatctc gaaagaacaa gtgttcatcg accagtggtg gctggtgcat 31921 tagacggcga taggtcttta gatatatcct taacggcaat atcgcttaca atgattcgtg 31981 tttcagggag agagactcgt gcaacggtat gtaggagcag ggattctaca gaacccgaaa 32041 ctggagtata tttccggttc ttttccactt gagaaaaact tttcgaaggt gatctgcggt 32101 tacatccgtc gctcgcaagg cgtttgtcgg agctagtata actctcatag cattgatatt 32161 gcgacaagag aatcaaattt gctggagaca tacaacgaac aaaaggctgc agaaagatga 32221 acatattgga aaatgaaaca aaaaagagga cgacgactcg tcaattaatg caactgaata 32281 ccaaacattc gaaaaccagg aacgcttctg acaccacgaa gagatatgcc gcccgtacga 32341 ccagatcgca aatcgatact gtagcagtcg gagttatgga cacgagtaca gcgctaagtg 32401 atgctacagt agttctggaa cagctcagca gtgatataaa taatattgag ggtaagtacc 32461 ataggccaaa aggcacgccg aaaatccatc ggtgtggtac cgtatggaaa agtttgaaga 32521 acgatcgtaa acatgaatgt tttatgctac agcgatatga tcagtgtctg tgatactgat 32581 gagcatgctg atgcgcatgt tgatgcgcat gctgatgata cggtggctgc gggtatggcg 32641 gctgctggta gggctgttga tactggcctg gatacggatt ataaggtgca ttcacgagca 32701 ccatcctgaa cggcgccatt attgcagaaa tgatccttcc agctgcatcc aaagtcgccc 32761 agatgacgat cagtgctagt atggcaccga ggatcttggc taccgagtcc cattgacacg 32821 gtggaggtgt aggtgccgga gctggatcgg gcgctttctt ctcctcctct ttcgggggcg 32881 gtggacagcc gtatacgtat gtcggaggct cgtctttcga gggtgggcag catggtttaa 32941 ccgggtggca gaagggacgc ggtccgggac ctccatccca gatgaatcgt ggatgtggcg 33001 ccgggggatc ttctttcttc ggaggaccca aatggatgtg aatgggcttc ttttcttctt 33061 tcggaggctc ctctggcgga tggatgatga cgggcccgaa tggagtatca aacttgttcg 33121 atggtttgtc tttcggcttg ggctcaggat tcaatgtcgt ccatcgatgg ctcgttgagt 33181 actttcgttc tacatctggc tccttttcgt ctttcatctt taggagctct ttccaacgtt 33241 gtcgcacggc gtgttctgag atcgtgggtc cgtcccgtgg gtagtcaatg tgccgataac 33301 tcattggtag aggcacatcg cccggaatga cctcatagcg ccatctatac tttatctcgg 33361 gtatctcttc tttttcctct ttcttcgctg gaggggcggg tggtgctggt gctggcggtg 33421 ccggtggcca ccatccgata acgtttttga ccatgctgca cgcaatgaaa gttatgagac 33481 cgtgtggtta acttttcggt tgatggagag ctcactcaag attagatcgt atcgaaaatt 33541 gttagaccat tgatcacgat ccagattccg ggaacagtgg agattgttgc gatattcaag 33601 gaagacttct taggcagggc taacccttcc agcgttggat acgttctcga attcaggtcg 33661 gaaacgatat tttagtgagc tgtacaaggc atgcgactgt acgaaatatt gggatgatga 33721 gagcatgtaa acacctccat gtgacggaat tttatcgtgg gatcaaggga tgtggcggga 33781 agcgaagaat gtgggtagtc ggcgacacaa cgcaagggag aaaggaatgt cgacatcagt 33841 aggtgaggca tgtagccttc aatgacaaat actcattcct tccatgagac cataaaacat 33901 ccacgatgat tcacatgtgc ctagtcgcac catgtattgc gcttcgcttg tggctctgaa 33961 agtcgatgtt cgcgataatg cttccccgtt cacaacagaa agacccgagc caactccctt 34021 tcttgtgtag aagccttttc ccttagtacg ccaggtattt cagaaactca agttcgctca 34081 tcaagaaacg ccgaatgctt tgtacgcctc gtctggttaa tcctcgtttg cgccatctat 34141 ctcagagtac tccttccaaa ggtcattcac acccttcttc catgttcgaa tggtgccgtc 34201 atctccagtg gatataagca agtccccttc aaagattagt aagagtgcga agagcagaaa 34261 cgtagggaag gtagacactc acccatcggt gagaacgcga cacgccagac tgcgccgtgg 34321 tgatttttca attcggccac ctttttgacc agatgcttga cccttccagg gatcgtaact 34381 tcttgtgaat cttcgttgga ttttgacgcg ccggcgagtc cagcaccgat gccagatgga 34441 ccagcgcgtg aaccacgggg gcgtggcgag cttcgaccgt cagtgtgacc gttgtgtatc 34501 gcaacagtcg tatccgatgc agattgcttg tcagtctcag cattgtgtag ctcgtagatc 34561 cgtatagctc catctttgct tgctgttgca atgatatcgt atcctctcat agacccgttg 34621 gcccacgaaa ggtctcgtac gatagatgta gcatcgttca attcggctgc aacataccac 34681 tttctgttct tgtctgtccg aaagatcttc accgtcttca tggctgctac agctagagag 34741 agtgacttac ggtcaaggcc ttcccgcaca gcagtccaac agggtagttt ttcgtggtgg 34801 aagcagacct tgaatccggc ttcatcctgg cgactaggag tggcacatac ataggaatca 34861 tgcagatact gccattcggc gatattgttg ttgtctaaag gttcatacac gctcagatgg 34921 ccatcgcgtg taatcagagc aaggtaggtg tcttgaaata tgttcttgaa gtccagtgac 34981 atatatggca cttttgtttc aggcgtcaga gtcgttacaa gcttgaaacg tcgaccagac 35041 tgagggactt cggtgacatc ttcctgccat agtttgaagc gaccgtcttc agcaacgctg 35101 cccagaattt ctccggcata tggtccattc catttaacct gatttgacat tagcatccat 35161 cttagctctt atagatctcg atgttccgcg aagtatcgaa tgtactgcgt gttgggttat 35221 aggtcaggga gtcgggaaag catggatgat gtgaaatgac cactcttgag agcaatgatg 35281 gctgtatagt gctaccacgc gctgtccaat agatacttac atcgacaatt tcagcatcat 35341 gggctctcca gctatcagcg aggttccagt tgtcgtcctt gcgatcccaa accttcagtc 35401 ggtgatctga ggaagctgtc accatacggg taccgaagta gttgaagtcg acggccagaa 35461 ccaaatcctg gtgtccatga gagaagctct ggaagccacg atcggtagcc atgcttttgg 35521 cagctttata ggctcgcaga acacttgctt gaagcttttg gcagacctta tgattcaacg 35581 tcagggctgc ggcgctacca tggctgagaa gatcgatagt gagaatatgg gcagcttcta 35641 tccgttcaac tctgctggcg aactcgacag ctgtatcaga caagttagac tgggtgcgtt 35701 tgcttgcctg aaagccaaaa gtagattttg tgggttcggg cgagatggag gagcaatcag 35761 aggcggcttg agagggaaga cgagaagctg aaatggactg taggaaagcg ggacggcaaa 35821 gcttcaagtt gacagcctcg agtttatctt tgataggatc attgatagaa tccaagacat 35881 ccgcttcgtc tcctccggcc tggcgagtcg cgcgacgttg gtgaggtttc tcacgttcca 35941 tacttgagtc ggagcgggcc aagggctact cttagctagt tagttggcta cgcttggggt 36001 ccttggggtg ttccaaggtt ggaaacggcg cgatctcagc ggtcggtgtc aactactgcc 36061 gccgcaacac caactaatca ggaaggtacg agccgactgg ccagaacaga cgcgacacgc 36121 cgccatagtt attaattaac cagacacctg gcgggaaaaa tcactcgtcc acttccgcgc 36181 ggctccattc tgcacttcac ttatcatgaa tttgtcgcta tatcgcgtct ctccctcctc 36241 atcggcgccg ccatcgcaat gacagtgtcg actagtctga gtcgcaccga gactctctca 36301 ttgttctcac tgtcggccgc ctgtgtcggc atcatcgcaa acacatttca aggcgacggc 36361 gaacccttga tcgcatcaat agctttcagc ggaattgcgt acgcttcgac atatgctctc 36421 ataagatggt tgggagacgt gttcatgcga gcgggcctga agggcagaga catgtccaag 36481 acaagaacag atgagatgta agagccgcac gcgcctgcgg aagactcgca atttcaatat 36541 gctgaccatg tttgcagtcc agagacaatg ggcgctgtat gcgctgtggt ctacctgctc 36601 atcatcatcg tcttcattcc cttcccgttc tacaaagaca tcgtcatggc cacgtcagga 36661 ggtggaaatc gcgatctggt gctggaggtc cagcacgtcg agactggcag actgctgcac 36721 cggttcccgc atagcaaggt tagacatgaa gaagtcttca cggaagtatt gagatgatga 36781 ctgactcttg tcagttatca tcctacttgt ccgcaatcct ctctatccaa tctgtagttt 36841 tgctcggagt aggtgacgat ctattcgaca ttcgatggcg gcacaagctg ttcattccag 36901 cattcgcggc gataccaatg ctcattgtct actttgtaga ctttggtgtt acccagatag 36961 tcatacccac accactgcgt tcctacttcg gagcgctgtt tgatctgggt aggatacatg 37021 cgttgcgaaa acagcgtgca taactgattt cgtacagggt ggttatacta cgcatatatg 37081 gcagcaatat caatattctg tccaaacagt atcaacatat tcgcaggcat caatggtatc 37141 gaggtgtctc aatcactggt cattgcctcc ttgatctgcc tcaatgatgc tctatacctc 37201 tcacccttta ctgagtatcc acacccggcg acagactcgc atctgttctc cctatacctc 37261 ctgcttccgt ttattggagt atcattagca ctctgggcac ataattggta tcctgcgcga 37321 gtttttgtgg gtgacacata ctgctatttc gcaggaatga tcttcgccgt tgtcggcatt 37381 cagggacatt tcagcaagac gctgttactg ctgttcatgc cgcagatttt caattttata 37441 tactcagcgc cgcagctctt ccacatcgtg ccttgtcccc gacatcggct cccgaagttc 37501 aatgcaagga caggactgct agaatgctcc acagcagaat tcagaaaacc actttcgcca 37561 ttggtatccg ctgttatgag gctaatgcac cgcctcaggc tacttcggat cgtcgaaaac 37621 gatgccggac agataacgga gagtaccaat ttcaccatca tcaatctgtg gctggtatgg 37681 tttggcccaa tgagagaaga ccgtttagct ataggactgc tcactatgca gaccatagtg 37741 ggtctcgtag ggctgttcat ccggcaccgg cttgcactgt gggtgtttac agcagacaat 37801 ttgcattata catattcctc tgcctaagtc aggccaaagc catggttctg ataagctgca 37861 acaggaacct cagcaacaag taaatgaatg gcatatatag acctacatgt atatagataa 37921 tgcacccacc tcctgaagaa ggggaagaca gccactgatc ggaacagcat gcagatcata 37981 tctgcagacc atatctgcag accataagcc gcgtgttcct acactctatg ggcctacctg 38041 tatgcgtgat ttatggacta cagtatgttt tcggagtaga gacctggagt cttggagact 38101 tggactccct tgcaagacga tggaagcagc ccaaaagtgc ggggcaaaaa gcgggagtgg 38161 actgttgaca ccgacgtccg agccagctga ccaatcacag cgcgtctctt tctaaacctc 38221 agcactgatg caagttccct ccgatctcgc tgcgctgctg cgatgctacc gaaacaatat 38281 ctgcctttcc actgcgtgaa atactgctct gtccgccctg cgtctctttg ataaccccaa 38341 tcgtctttca gactgctcat tcgtctcttg tgtttcttgc acgctcttcc agtactttcg 38401 catctagttc cgtcgtctaa gcgaccccac tatacgccat gcctggagct ataaaaaaac 38461 ctcagactct ctacgacaag gtcttcgagg ctcacgtagt caatgagcag gaagatggta 38521 ctatccttct ttacattgac aggcatctag ttcacgaagt cacatctccg gtctgtacat 38581 tccgttgcgc taaaaaggca cgtcctgacc atttactagc aagcattcga aggcctaaga 38641 aacgctgggc ggaaagtgcg tagacctgac tgcactttgg ccacgactga tcatgtatgt 38701 cttgcatctc gttgacttgg tcacaatgat agtagaatta acaaccagca gaatgtaccg 38761 actacccccc gtaaaaactt taaaggcgtt gcagacttca tcaaagagga cgattcgagg 38821 acacaatgtg tgactctaga ggataacgtc aaggcctttg gtctcacata ttttggcctt 38881 ggtgacaagc gccagggtat cgtgcacatc attggtccag aacagggatt cactcttccc 38941 ggcacaacgg tcgtatgcgg tgacagtcat acgtcaaccc atggtgcatt tggcgcattg 39001 gcctttggta tcggaaccag cgaggtagag catgtcttgg caacccagac tctcctcacc 39061 aagagaagca agaacatgag ggtacaagtt gatggagagc tagctcctgg cgtcagcagc 39121 aaggacatta ttctgcacgt tattggtcag atcggtactg caggtggtac tggagctgtg 39181 atcgagttct gcggttctgc gatccgcaat ctaagcatgg aggcccgcat gtctatatgt 39241 aacatgtcca tcgaaggtgg tgcacgagcc ggcatggtcg ctccggacga gacgactttc 39301 gaatatctca agggccgccc attggctcca aaggtcgata gcgccgagtg gaagaaggcg 39361 acagcctatt ggtcatccct gaagtccgac gaaggtgccg aatatgatct agatgttttc 39421 attgacagca aagacatcgc acctacggtc tcgtggggaa cttcacctca ggacgtggtt 39481 ccaatcacag ggaaggtacc tagcccagac gatttccaag acgaggacaa gcggaaagca 39541 tgcattcgcg cacttgatta catggggctt gaagctggaa cccctatgca ggaggttgtc 39601 ctcgacaaag tcttcattgg atcgtgtacc aatgcccgaa tcgaagatct ccgcgccgct 39661 gctcggatcg tgaagggaag gaaagtagca tcaaatatca agcgcgccat gatcgtcccc 39721 ggctccggtc tcgtcaagca acaggctgag tccgaaggtc tcgacacgat cttcacagat 39781 gctggattcg aatggcggga agcaggctgc tccatgtgtc tgggcatgaa cccagacatc 39841 ctctccccca aagaacgctg cgccagcaca tccaaccgca acttcgaggg acgccagggt 39901 gcaggcggcc gcacacatct gatgtcccct atgatggccg ctgcctgtgc tatcgccggt 39961 aagcttgccg atgtgcgcaa aatcgccaac tttcaaccca gcgatgttgc gcaaggcagc 40021 ccgaaagtcg acgtcgcacc cgcacaccag tccgacatcg aatcagacga agacctcgac 40081 aggattgctg acgctcctga agacagccct gccactgttt ccggtaacaa caaatccgcc 40141 tcctcatcga gtggcggcat gcccaagttc gagaaactca agggcatcgc cgcgcccatg 40201 gacgtcgcca atattgacac cgacgccatc atccccaagc aatttctcaa aaccatcaag 40261 cgtagcggct tgggttctgc attattctac agctggcgct tcgccgacga cggcagcgaa 40321 aagaaagact ttgttctcaa tcaagagcca taccgcaatg ccaaagtgct agtcagcaca 40381 ggcaagaact tcggctgcgg cagctcgcgc gaacacgcac cgtgggccct cctcgacttc 40441 ggcatcacat gtatcatcgc gccgtcgttt ggcgacatat tcttcaacaa cacgttcaaa 40501 aacggcatgc tcccattgcg cctcacgccc gaacagggcc tcgatgccgt tgctgccgag 40561 gcccgcgccg gccgcgagat cgaggtcgat cttcccgggc aggtgatccg tgacgccgac 40621 gggaagcaga tcgcgacctt cgaggtggag gagtttagga agcattgcct gttgaacggg 40681 ctggatgata tcggcttgac gttccagcaa gacgataaaa tcaaggcgtt tgaggggaag 40741 aggagcagag aatatccatg gctagacggg agcgggtact tgaggaagca caggcctgga 40801 gaggcggtga aggtcgaggc cgtgccagtg ccgaagacga acaggggaga ggtcaagggc 40861 gagccgttgg agtggtagat ttaatacgtt gttctgttga gcggatactg tgtattgcgc 40921 cggaatggca gaaaaggtaa gaagaagtgg gaggttaatg attcgacaag tcgattcttt 40981 tgttttttca aacggccgac tcatgggagc ggaaggcata cgtgcgtgga cgctggcggt 41041 acggcgtgga cacacgctgg aataggcaat ttacggtaca taggtcatgc aaatacttgg 41101 ttgatgattg tgcttctcat acgtctacat ctggctcgag gcttccacgt gaggtagtgc 41161 tggcagattc aaatcgagtc actcctccaa gctgttgtgg aacgtgatag atcaggccga 41221 gacagccgta tcaatactag tttctcatgc gccaggcaag atgtgtccct cacaacagct 41281 ttgcagatgt cggcgcgcct gaaacagtgg aacagggcgt acctgatagg aggaagcatg 41341 gctcagcaat atggaagtgc tagtgtcacg tcgtgctgct gttgcagtct tgcctgccag 41401 gatcagagcc tgtggttggc ttaacaaacg ccatatcgtt taccatcggg tgcaacacgc 41461 tcctctgaag cctcatgggc aatgaatggc gatatcttcg acccccgggt acgccgccct 41521 cacttcacct ttacgccgtc cagcttcctc tcgacgactt ttaccaagtc catctgcacc 41581 agctcattcg gatcgcgcat gacgctcaac gcgcgcgcgt ccgcgacgcc ctgcctcctc 41641 agaccctccc ttaccttgct atactcttct tccctagcgc agtactcgcg tatgacgacg 41701 ccggtttcaa actcgatata cactctggtg tcgcgaatgc ggaacaggac gtcgtctaag 41761 cgcatgaaaa agcgtgctag gatgagcagt cgctggggca tgacgcggag tttgacggtg 41821 tagaaggaga tgccgttgtc ggcgagctcg tcttcgtaga ggggtacttc gtcgaagagg 41881 aggatggggt ctcggcgggc gagcagatgg agtgggagag gggtatctgt tgtggagaat 41941 gttggtggtg gtgagggacg agtggtcggg gacgcagggg atggcgagga tccggcgtag 42001 tcggtggtgt acgaccagtc gaaaggcttg atgacttcct tgatatccga ggaatggtgt 42061 tgcctgtgac gtacacacaa attaacaaga tggacgcaag gcaaagtggt gtgtcagcgc 42121 agcccaatac acgatactca gccctccgca ttgaagctcc aaacggcagt cccatcctgg 42181 aggagcccga cggagcgtca tcgtacatta acgcactgcc agtggcgcgt gggcgtgtag 42241 agcgaattag cactcaccga ttctcctgcc actcacgaga ataggcaact ttcagcatcg 42301 acttgtcggt tttgtccact ctgtccagcg cgtcgccggc gttaaactcg atggcccagc 42361 cgctgaccgg atgctccacg cgcacgtagt tgtcgccaaa gatcatctca gggattgcaa 42421 tgcccaggcg ttcggccagc ttctcgatcg ggtctgcctt gaggatgggc agcttgcgcg 42481 tggatatcgt gaagccatgc tgcgatatgg actttacggc gggggactgt ggggtgggca 42541 actgggtgtc tggcggcggg agagagacgg aggggctcgg ggacaaggcc gaagcggtat 42601 cggcggtggt cgtcattatt gggcgatcct ctctacagcc agatcgacag tgccgtgagc 42661 tttacaggcg ttgtgtggtg caaagaaaga gaaaaagaat gatggtgaag gaggagactc 42721 atatcatggt ttttagcggc tcagggccac aatcttaggc tgaattcagg catcgatcat 42781 agttcaatcc agcggggggt gcaggtggtg cgtgcgcctg ccgggttgtt ggttgttgtt 42841 gccctgcgct acgtgcgacg tcgctggccc agtcaacaat actaaacctg catgctcgct 42901 cattcactca ctccagctcc ccctccctct ctccctctga cgcactcatt cacagagcct 42961 ggaaaggacc cgagttgcaa cctttgctcc ttctcaacaa ctttacttta cgataaacca 43021 cccatcccct cagacacgtt ctgcgacagc actgcttgtc gccctaattt gtcctttcta 43081 cctacattac tccatctctt gtttctttgc gccatatagc tttatatcaa atggcggata 43141 caagatccct ggaagatcgt tttgaacgaa tcactgttac tgacgagaat gatggcggct 43201 atattactca gacgaccacg taccaccata agtcgaaggt agactcgcaa tagtgtagca 43261 ttgtataagt cactgctaac aagtccaggg ctctctctca cacgcaatga acctcactgg 43321 attgggccaa ccaacgaacc cgaaccgtat gaagttacct ctacaacgcc cgcccaccca 43381 gagtcaaccc aaatctgtca cgacaacaat tacgaaagtc accaccgtac cgacgcatcc 43441 accgagcaat ccataccatg actcgttcgc cagctcaggt gtctcgctgt catcacgctc 43501 ctcggatgag atgaccgttg cacaagtcgc cagacaatcc atgtacaacc ccttccctcc 43561 aaacaagaaa tggcacctca gcatgttcga gattggcaag ccactcggca aaggcaaatt 43621 cggaagagtc tatctcgcga aggaaaaggc tacgggcttc gtctgtgctc ttaaggtcct 43681 gcacaaatca gaaatttcgc aaggcaaagt cgaaaagcaa gtgcgccgcg aagtcgagat 43741 tcaatctaat ctctgccacc ccaatgttct caagatgttt ggccactttc acgactccaa 43801 gcgcatattt ctcataatcg aattcgccgc cagaggcgag ctctataagc acctccgcgc 43861 cgagcagcgc ttcgctgaac ccaaggccgc aaattacatc gcacagatgg cttccgcact 43921 caaatatttg caccacaaac acatcatgca ccgcgatatc aagcccgaga acatcctggt 43981 cggtatccat ggcgagatca agatttcaga cttcgggtgg tccgtccacg cgcccaacaa 44041 ccgccgcaat accatgtgtg gcacactcga ctatctgcct ccagagatga tcaagggcac 44101 cgacggctac tccgagaaag tcgatctctg gtcgctaggt gtacttacct acgaattcct 44161 tgtcggcgaa gcgccctttg aagacgcgcc tatgatgacg cacaaacgca tccagcgctg 44221 cgacatgaca attccgtcct tcatatcctc agatgcgcgg gatctgatca gaaaactgct 44281 acaggtagat cctgagaagc ggattacctt ggatgagata gaacggcatc cgtggatcgt 44341 gaagcatgta accaccagcg cgagagcgta tgatcgtggg agcaacagca gtcgtggcag 44401 tgcgagtagt gggagtgagt cgtgacggat agtgaggagt caaccacgac agaccgttgg 44461 gacatctgct aggagcgcgc ccgcgtcggc cagaagcccg cagcaggttg tcaggagtcc 44521 acatcagctt gtcaggagcc cgcagcaggt tgtcagaagc cctcaacaag ttatcagaag 44581 cccgcagcag cctatcagaa agccgcatag tgccacaagt ccgcgtacag tggtgcagca 44641 ggttgtgaca agctacaaat acggtgtcta atcaacaaaa cgcaccgagc atattgttcc 44701 tagtactttc gcttctagcg gtctggtggt ggtatgatct ggtgtgattt gaacgtagta 44761 acgatgccgt ctgttggcac atgggtgttt tatttcttct ttggctttcg gtatatatca 44821 tggtatatga gttgtttttc tgggtctggg cgaggcgttt accgggcatt gcttaaaaca 44881 ctttcatgga ctttcaaaac gattgttgtg atggagctat cgtagcatac gcggtgcaca 44941 tttggttggc atcagaaacg ggaatacatc ttattggcat catcatttga ggtgtattct 45001 tgtgtgatat gttgcctcta tcgtccctga cgactcgtct ctttgcgcgg tggcgaaacg 45061 ttcacactat aggcaactgt ctgaggatat cttagatgta tctggacgtc tttatacaat 45121 cgcgtattga tacactcaac tttgtgtagt gcatgggctc atctgtttgg acacgccagt 45181 gcaggaagat tggacgcggt ccgtctgtga attcggtatt ccaggctgca gatcccgatc 45241 cttgccgcca ttcgaattgc tccttgaaga agacaaaaca tccaatcgta aacgagcccc 45301 agctatccga atagatctca aagggatgtt gtgaaagcac acgttgtggc tcacgacagc 45361 tagggtgctg cgatcataaa tcaacttgtg gggttccctt gtgcctgtca tgatggactg 45421 aacattaact gtgggacgct taccagaaaa catattactt tatcaatgac atctggatta 45481 gatggccaca ggaagaaaca ccacttgaac cgggtttcac cggggcggtc ttcgtacgaa 45541 ttcccgtagg taatggttag gtcctccatt tctttgactt gtccaaattt cgaccagatg 45601 tggattgggg cgcaacaagt ctggcacagt tttgtaggtc ctactatctc gtctagtagt 45661 tgcaggttgg cgttcaagtg cttgatacct ggtcgagatg gtggctgatg acgcagcatc 45721 atccgcacat cagtcatcaa gaacgtgtct cgtagagagt tcagagctat gacgttgaac 45781 cagttcacga tatgatctag attggcatgg aatgatcggt ctctggctgg cctgagagct 45841 tccaactctt tcaaagaata gccgttacag ataccgacaa tctccaagat gatgcatcca 45901 aaggagaaca tttccgccga cctaccagca ccctcgtacg ccgcaacttc cggggcaaag 45961 tatttcggag tgccacgttc gccaccttcc gtaacacttt cggcatctgt cgagaagtcc 46021 gacgaggtgc caaaatcggt cagccaaagc ctgccgtcct ggccgagtag gatatttgct 46081 ggtttcaagt ccttgtgctt gattttatta tcgtgcaagt acgcaattgc ggaagctgtg 46141 cagccaatag tgttgtatag tcgagtagat atcgagtcct ggttaggcgt gtcttcacat 46201 agaagatgag atattcgaag tctggatagg gcatactgac tagcgtcgtg tccgtcactg 46261 tcttcatggt acagatggtc aacatcttcc atgaacgagg ctaggtcgca ggtagcgacc 46321 gggtacagta aaagtccaac gataggccct ttcgtatagg ttccgaccaa ttggatgatg 46381 tgacgatgcc gcaatttctt caaaatgtca atttcttttc tttccctgtc acccagttgt 46441 cttctggtga atttgcgttt ccaggcgatt gctttgcctt gaactacagt ctcatacacg 46501 ccgccgtgga cgccgtgccc cagaagcctt ccttcgacca acggaacctt ctcctcccgc 46561 gtaaattcaa catgagagct tcctcggtcg caccagtccc aatcgtatgt agtcggttgg 46621 aggtccggcg gcggtgagca gtttgtatgg tacttatgat actcgaaata ttgatacaca 46681 cccggtatag acacccgagg actcgcatca ccatgcccgt tcatagcact gacactctga 46741 cgcgcgatta caggacttga gattccagtg gagtccttca ggtcatcgag accagcatcc 46801 cagccccaag acatgttgtc caggctttga gcaggtcaag acacgcttgg tacaacacaa 46861 gaggtacaag ttcaatgatg ggagcgtgag cagcctctcg aagaagagtg agaaggctgt 46921 catcgcgtct cgctgcattc tgcattcaag tcacagcctc gctgctcagc ggcgggcgca 46981 cgcaggtgat tcgctggctg caacgccaat cctccattta tggggccaca tgctgttagg 47041 gaaggtcgta ctttgatgca tagcatccgg gaccatgaca atggactgtt gggcgcagtc 47101 ttgggaaagt aaggacatgg aaggaaacaa ggtgaattga agctactata cactacggag 47161 gaagtaatag atcttagcat aagtgtgcac ggccggtgtt tccacgtaca gaaggaacgt 47221 accaggcccg tgcgcaaatt tccatccgac gtcagtatcg cgaacgaacc cagaaacctc 47281 aatcacaacc tccatcccat atcgaatccg atccaccacc tcctctctct ctctctctct 47341 ctctctctct ctctctcaca aaatccacaa tgtccacaac caccacagac acacccgccc 47401 cccaacaacc cgcctcaccc cctccctcca ccccaacaga cgcctcccaa ctaaacacct 47461 actacacctg gagcaccttc ttcaacatcc tcctctcccg ctccacgccc acggaaacag 47521 cctcctactt cgccgcgcgc gacctcgcca acgaagccag cgactgcgcc cgctgcaccc 47581 aaaccgtcac ctcgctcttc aaaacctcgc ccatcgtgcg cttcctccgc gacgaaacgc 47641 gcgccctcag tggcggccgc cacagcgaaa ttggccccgc gcagatccac tgtcgccgct 47701 gtaccacgcg gcagagcggc gggttcgaca tggactatgg gattctgctg tgtgcgaatc 47761 atctgcagag tagggcgcag acggaggata cgctggcgca tgagctggta catgcgtatg 47821 atcatttgcg gtttgatgtg cagaggacgg acttgaggca tcaggcttgt acggaggtgg 47881 gttttgtgct tgctgtctag cctatataca tatacccaca atcccccgtc accacctact 47941 aacatacaac t //