# HG changeset patch # User iuc # Date 1723410540 0 # Node ID 3447eb0ce896925c727a9497a18899d5f0c5f724 # Parent ad2f19722a0e16eba28c617893df393b5667b013 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/bigscape/ commit 8a0f3092ca824856263328efe66941409f527ca4 diff -r ad2f19722a0e -r 3447eb0ce896 bigscape.xml --- a/bigscape.xml Fri May 17 12:36:26 2024 +0000 +++ b/bigscape.xml Sun Aug 11 21:09:00 2024 +0000 @@ -2,7 +2,7 @@ Construct sequence similarity networks of BGCs and group them into GCF 1.1.9 - 1 + 2 BiG-SCAPE @@ -17,7 +17,7 @@ mkdir -p '$path_to_html' result input && #for $files in $inputdir: #set $filename = "region." + $files.element_identifier - ln -s '$files' './input/$filename' && + ln -s '$files' './input/${filename}.gbk' && #end for mkdir pfam && @@ -296,7 +296,13 @@ - + + + + + + + diff -r ad2f19722a0e -r 3447eb0ce896 test-data/NC_012963.1.region001.no-genbank-suffix --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/NC_012963.1.region001.no-genbank-suffix Sun Aug 11 21:09:00 2024 +0000 @@ -0,0 +1,2823 @@ +LOCUS NC_012963 44203 bp DNA linear CON 17-FEB-2023 +DEFINITION Komagataella phaffii GS115 chromosome 1, complete sequence. +ACCESSION NC_012963 +VERSION NC_012963.1 +KEYWORDS . +SOURCE Komagataella phaffii GS115 + ORGANISM Komagataella phaffii GS115 + Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; + Saccharomycetes; Saccharomycetales; Phaffomycetaceae; Komagataella. +COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final + NCBI review. The reference sequence is identical to FN392319. + Contact: Nico Callewaert + Unit for Molecular Glycobiology + Laboratory for Protein Biochemistry and Biomolecular Engineering + Department of Biochemistry, Physiology and Microbiology, UGent VIB + Department for Molecular Biomedical Research, UGent Technologiepark + 927, B-9052 Gent, Belgium + Tel: (32)93313630 + Fax: (32)93313609 + Email: nico.callewaert@dmbr.vib-UGent.be + ----------- sequencing/assembly + Unit for Molecular Glycobiology + Laboratory for Protein Biochemistry and Biomolecular Engineering + Department of Biochemistry, Physiology and Microbiology, UGent VIB + Department for Molecular Biomedical Research, UGent ----------- + annotation + Unit for Molecular Glycobiology + Laboratory for Protein Biochemistry and Biomolecular Engineering + Department of Biochemistry, Physiology and Microbiology, UGent VIB + Department for Molecular Biomedical Research, UGent + Laboratory for Bioinformatics and Evolutionary Genomics VIB + Department of Plant Systems Biology, UGent + Web site: http://bioinformatics.psb.ugent.be/ + Bioinformatics Online Genome Annotation System (BOGAS): + http://bioinformatics.psb.ugent.be/webtools/bogas/ ----------- + * NOTE: finishing of chromosomes in process + * Final curation of the annotation in progress. + ##antiSMASH-Data-START## + Version :: 7.1.0 + Run date :: 2023-11-19 21:18:41 + NOTE: This is a single region extracted from a larger record! + Orig. start :: 1667272 + Orig. end :: 1711475 + ##antiSMASH-Data-END## +FEATURES Location/Qualifiers + protocluster 1..44203 + /aStool="rule-based-clusters" + /category="NRPS" + /contig_edge="False" + /core_location="[20000:24203]" + /cutoff="0" + /detection_rule="cds((PP-binding or NAD_binding_4) and + (AMP-binding or A-OX))" + /neighbourhood="20000" + /product="NRPS-like" + /protocluster_number="1" + /tool="antismash" + proto_core 20001..24203 + /aStool="rule-based-clusters" + /tool="antismash" + /cutoff="0" + /detection_rule="cds((PP-binding or NAD_binding_4) and + (AMP-binding or A-OX))" + /neighbourhood="20000" + /product="NRPS-like" + /protocluster_number="1" + cand_cluster 1..44203 + /SMILES="NC(CCCC(=O)O)C(=O)O" + /candidate_cluster_number="1" + /contig_edge="False" + /detection_rules="cds((PP-binding or NAD_binding_4) and + (AMP-binding or A-OX))" + /kind="single" + /product="NRPS-like" + /protoclusters="1" + /tool="antismash" + region 1..44203 + /candidate_cluster_numbers="1" + /contig_edge="False" + /product="NRPS-like" + /region_number="1" + /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding + or A-OX))" + /tool="antismash" + gene <1724..>3658 + /db_xref="GeneID:8197127" + /locus_tag="PAS_chr1-4_0143" + mRNA <1724..>3658 + /db_xref="GeneID:8197127" + /locus_tag="PAS_chr1-4_0143" + /product="Type II phosphatidylinositol 4-kinase that binds + Las17p" + /transcript_id="XM_002490207.1" + CDS 1724..3658 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0143" + /db_xref="EnsemblGenomes-Tr:CAY67971" + /db_xref="GeneID:8197127" + /db_xref="GOA:C4QXJ8" + /db_xref="InterPro:IPR000403" + /db_xref="UniProtKB/TrEMBL:C4QXJ8" + /locus_tag="PAS_chr1-4_0143" + /product="Type II phosphatidylinositol 4-kinase that binds + Las17p" + /protein_id="XP_002490252.1" + /transl_table=1 + /translation="MDSKPLSGVSLAEASNLNLDPSVQLRSNSSIQENYPDPANVYTEQ + LGHSPSERDTLLPQSPNYNATSPSQGAGRSPLSKKKRTRSLLSTDKLKSLNTKLGKWTR + GLSYKWWIVRSKDVEGQPSEILFSVFMAPPYVQPLRRLPAGGLMNMGPTSREDFAHIVD + DVIDAIEQGIKPTRISQGSSGSYFMYNTQGKIVGVFKPKDEEPYGPLSPKWTKWIHRNL + FPCFFGRSCLIPNLGYIAESAASLLDRQLQSFIVPYTDTVLLSSSSFYYAFWDRCTHAW + SKKPYRKKVGSFQLYLNGYIGADEFFKKYPLPADKGRSLLPFLPDKHKKKKTSKKRQRG + DTRHSIFDKDTVFEWNRDTLQQLREQLEKLVILDYIIRNTDRAFDNWMIKVEWDEYLDE + EANEAYKRPNLKVRAIDSGLAFPWKHPNEWRSFPFGWLYLPTSVIARPFSERTRRHYLP + LLTSKEWWEETSVLFREMFSRDTEFKERMWRRQWAVLKGQAFNVVETLKIPGQSPLDLV + QKTRIMVWDNVVEIPVSYVPRDIDIYNDSPVWTYQNYDEEYWSSNIAHNSPGRYHEHEP + TTPESECLDDPFSSAASTDRGGYAISSNANTPGRANTDSIQKPTTATRRLIVERLETIT + SKPPVFTWC" + PFAM_domain 2264..3229 + /aSDomain="PI3_PI4_kinase" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00454.30" + /description="Phosphatidylinositol 3- and 4-kinase" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0143_0001" + /evalue="9.30E-47" + /label="PAS_chr1-4_0143" + /locus_tag="PAS_chr1-4_0143" + /protein_end="502" + /protein_start="180" + /score="160.1" + /tool="antismash" + /translation="GSSGSYFMYNTQGKIVGVFKPKDEEPYGPLSPKWTKWIHRNLFPC + FFGRSCLIPNLGYIAESAASLLDRQLQSFIVPYTDTVLLSSSSFYYAFWDRCTHAWSKK + PYRKKVGSFQLYLNGYIGADEFFKKYPLPADKGRSLLPFLPDKHKKKKTSKKRQRGDTR + HSIFDKDTVFEWNRDTLQQLREQLEKLVILDYIIRNTDRAFDNWMIKVEWDEYLDEEAN + EAYKRPNLKVRAIDSGLAFPWKHPNEWRSFPFGWLYLPTSVIARPFSERTRRHYLPLLT + SKEWWEETSVLFREMFSRDTEFKERMWRRQWAVLKGQAFNV" + gene <3761..>4714 + /db_xref="GeneID:8197128" + /locus_tag="PAS_chr1-4_0144" + mRNA <3761..>4714 + /db_xref="GeneID:8197128" + /locus_tag="PAS_chr1-4_0144" + /product="pyridoxal kinase BUD16" + /transcript_id="XM_002490208.1" + CDS 3761..4714 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0144" + /db_xref="EnsemblGenomes-Tr:CAY67972" + /db_xref="GeneID:8197128" + /db_xref="GOA:C4QXJ9" + /db_xref="InterPro:IPR004625" + /db_xref="InterPro:IPR013749" + /db_xref="InterPro:IPR029056" + /db_xref="UniProtKB/TrEMBL:C4QXJ9" + /locus_tag="PAS_chr1-4_0144" + /product="pyridoxal kinase BUD16" + /protein_id="XP_002490253.1" + /transl_table=1 + /translation="MVTPANKIISIQSHVAHGYVGNKVAGFVLQCQYWDVDLLNTVNFS + NHTGYGSFKGQATTGEQVLSLYEGLQDINVQYDAMLTGYIQGADGVEAMGKVCLDLKER + TPGILWLLDPVMGDEGELYVSADVIPAYRRILGYKKVDIITPNQYEAELLVGFSINNTD + DLRKALKVFHEDFNVMHVVISTFSFTKNKDFFYCVSSTKTSYKKPNFFKIPYMDSYFTG + VGDLFSALLVDKIYRLPGGEPIEPAVSNALTIMEKVLDVTRRLCVDKLGVAVQGKIGDA + ETMKECELRIVECRQFYTMKDRNFNCETKILTDSQA" + aSDomain 3776..4603 + /aSDomain="TIGR00687" + /aSTool="tigrfam" + /description="pyridox_kin: pyridoxal kinase" + /detection="hmmscan" + /domain_id="TIGRFam_PAS_chr1-4_0144_0001" + /evalue="4.20E-52" + /identifier="TIGR00687" + /label="PAS_chr1-4_0144" + /locus_tag="PAS_chr1-4_0144" + /protein_end="281" + /protein_start="5" + /score="175.2" + /tool="antismash" + /translation="NKIISIQSHVAHGYVGNKVAGFVLQCQYWDVDLLNTVNFSNHTGY + GSFKGQATTGEQVLSLYEGLQDINVQYDAMLTGYIQGADGVEAMGKVCLDLKERTPGIL + WLLDPVMGDEGELYVSADVIPAYRRILGYKKVDIITPNQYEAELLVGFSINNTDDLRKA + LKVFHEDFNVMHVVISTFSFTKNKDFFYCVSSTKTSYKKPNFFKIPYMDSYFTGVGDLF + SALLVDKIYRLPGGEPIEPAVSNALTIMEKVLDVTRRLCVDKLGVAVQGKIGDA" + PFAM_domain 3983..4537 + /aSDomain="Phos_pyr_kin" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF08543.15" + /description="Phosphomethylpyrimidine kinase" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0144_0002" + /evalue="1.10E-11" + /label="PAS_chr1-4_0144" + /locus_tag="PAS_chr1-4_0144" + /protein_end="259" + /protein_start="74" + /score="44.7" + /tool="antismash" + /translation="VQYDAMLTGYIQGADGVEAMGKVCLDLKERTPGILWLLDPVMGDE + GELYVSADVIPAYRRILGYKKVDIITPNQYEAELLVGFSINNTDDLRKALKVFHEDFNV + MHVVISTFSFTKNKDFFYCVSSTKTSYKKPNFFKIPYMDSYFTGVGDLFSALLVDKIYR + LPGGEPIEPAVSNALTIMEKVL" + gene <5176..>7806 + /db_xref="GeneID:8197129" + /locus_tag="PAS_chr1-4_0656" + mRNA <5176..>7806 + /db_xref="GeneID:8197129" + /locus_tag="PAS_chr1-4_0656" + /product="uncharacterized protein" + /transcript_id="XM_002490209.1" + CDS 5176..7806 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0656" + /db_xref="EnsemblGenomes-Tr:CAY67973" + /db_xref="GeneID:8197129" + /db_xref="GOA:C4QXK0" + /db_xref="InterPro:IPR001680" + /db_xref="InterPro:IPR002933" + /db_xref="InterPro:IPR011650" + /db_xref="InterPro:IPR015943" + /db_xref="InterPro:IPR017149" + /db_xref="InterPro:IPR017986" + /db_xref="InterPro:IPR019775" + /db_xref="UniProtKB/TrEMBL:C4QXK0" + /gene_functions="other (smcogs) SMCOG1173:WD-40 + repeat-containing protein (Score: 83.6; E-value: 2e-25)" + /gene_kind="other" + /locus_tag="PAS_chr1-4_0656" + /product="uncharacterized protein" + /protein_id="XP_002490254.1" + /transl_table=1 + /translation="MNPLDVIGSDGNNHVSKQLPLKTASSCFNSSFSSLTKQFTPELLK + SDNESVESLANYPLLTDNPSLVHQWNHEYSVVCVSVSSSRGLLFCGTQDAKILVFDLNT + YEKIHVLQAHEGAVLCLEISANEKFLFSGGSDSLLRIWDLETMTERFTIYSLMDIGDIF + SITWIQDLNMVFFGTQNACILYAYVEVDGSWKNDPSFLPANRYDNFFDSKGPGGNMNPK + QSKKNKQHTSPLVEVDTYNILRYAHNGYVYAMQSFKRTPETVEIFINIPNIYNHILVSG + GGDGLVKLWGVGSDRSVVALHELDNEDSVLSMVISGSFLYAGLVDGQVNLWDLGTFQLI + RSTKTDEGDVLSLALYADCLFKGTEHGITKWKLQGARRTDWVTHEGYALTVKLFERQGN + PYLITGGVNNRLALWSLDGVYSASKRRSLSLSKKSILPLDNDSLLQTLAKFVSYKTVSK + LPQFFIDDSRRCASFLVNLLTSFGATAQLIPVKNGNPIIHACFPAQVINSAKKKPSRIL + WYGHYDVVSADQSNGWVQDPFKMSAMDGYLYGRGVTDNKGPLLAAIYSVAELFSQDALK + SDVVFLIEGEEESASFGFQEAVGAYKDVVGEIDWIFLSNSYWIDDHLPCINYGLRGVVG + VKVEISSDKPDRHSGVDGGVSREPAVDLVKLISKLTSDEGRILLPGFFDGLNPPSEEEE + KDYERILERAKIKSSKEMLMAKWRYPSLTVHKVTVSGPGNNTIIPQMASAAISLRITPE + QNLESVKNMLVSFLKDKFKDLKTENECKISITHEAEPWLGDRRNTGFQVLENAIINEWG + IEPLYIREGGSIPSIRFLEKAFGAPAIHYPCGQASDNAHLDNERLRVRNLYKSRNILNR + VFQTL" + PFAM_domain 5491..5604 + /aSDomain="WD40" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00400.35" + /db_xref="GO:0005515" + /description="WD domain, G-beta repeat" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0656_0003" + /evalue="3.30E-05" + /gene_ontologies="GO:0005515: protein binding" + /label="PAS_chr1-4_0656" + /locus_tag="PAS_chr1-4_0656" + /protein_end="143" + /protein_start="105" + /score="24.7" + /tool="antismash" + /translation="EKIHVLQAHEGAVLCLEISANEKFLFSGGSDSLLRIWD" + PFAM_domain 6727..7794 + /aSDomain="Peptidase_M20" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF01546.31" + /db_xref="GO:0016787" + /description="Peptidase family M20/M25/M40" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0656_0004" + /evalue="1.30E-23" + /gene_ontologies="GO:0016787: hydrolase activity" + /label="PAS_chr1-4_0656" + /locus_tag="PAS_chr1-4_0656" + /protein_end="873" + /protein_start="517" + /score="83.9" + /tool="antismash" + /translation="WYGHYDVVSADQSNGWVQDPFKMSAMDGYLYGRGVTDNKGPLLAA + IYSVAELFSQDALKSDVVFLIEGEEESASFGFQEAVGAYKDVVGEIDWIFLSNSYWIDD + HLPCINYGLRGVVGVKVEISSDKPDRHSGVDGGVSREPAVDLVKLISKLTSDEGRILLP + GFFDGLNPPSEEEEKDYERILERAKIKSSKEMLMAKWRYPSLTVHKVTVSGPGNNTIIP + QMASAAISLRITPEQNLESVKNMLVSFLKDKFKDLKTENECKISITHEAEPWLGDRRNT + GFQVLENAIINEWGIEPLYIREGGSIPSIRFLEKAFGAPAIHYPCGQASDNAHLDNERL + RVRNLYKSRNILNRVF" + gene complement(<7821..>8807) + /db_xref="GeneID:8197865" + /locus_tag="PAS_chr1-4_0145" + mRNA complement(<7821..>8807) + /db_xref="GeneID:8197865" + /locus_tag="PAS_chr1-4_0145" + /product="pirin" + /transcript_id="XM_002490210.1" + CDS complement(7821..8807) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0145" + /db_xref="EnsemblGenomes-Tr:CAY67974" + /db_xref="GeneID:8197865" + /db_xref="InterPro:IPR003829" + /db_xref="InterPro:IPR008778" + /db_xref="InterPro:IPR011051" + /db_xref="InterPro:IPR012093" + /db_xref="InterPro:IPR014710" + /db_xref="UniProtKB/TrEMBL:C4QXK1" + /gene_functions="other (smcogs) SMCOG1208:pirin + domain-containing protein (Score: 191.5; E-value: 3.1e-58)" + /gene_kind="other" + /locus_tag="PAS_chr1-4_0145" + /product="pirin" + /protein_id="XP_002490255.1" + /transl_table=1 + /translation="MSRSVLKSFYCNEVSEGVGAKVRRSIGSMQMRNFKPFLLLDHFNV + DPSAGFPDHPHRGQETITYMTKGQFAHQDFTSDKVGILNAGDCQIMRAGRGIMHAEMPV + QGKSGENIVGMQLWVDLPKHLKHSEPEYRDLRASEIPTVTPNDKVTVKIISGKAYGVEN + FQDLSYSPVDYYYYTVQPGGSFEQSVGENYNSFIYLLDGSLEINNKTYDKFNALFFDLN + GNKITGSVPEDATSPAEFVLVAGQILDQPIVQHGPFVETSKDLIYKAFMDYQTASNGFE + RGKDWRSKIADGVKEDDLAKLKQLFYYYLLHHLYSSYLFTLCIFINY" + PFAM_domain complement(7974..8285) + /aSDomain="Pirin_C" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF05726.16" + /description="Pirin C-terminal cupin domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0145_0006" + /evalue="6.10E-18" + /label="PAS_chr1-4_0145" + /locus_tag="PAS_chr1-4_0145" + /protein_end="278" + /protein_start="174" + /score="65.3" + /tool="antismash" + /translation="YYYTVQPGGSFEQSVGENYNSFIYLLDGSLEINNKTYDKFNALFF + DLNGNKITGSVPEDATSPAEFVLVAGQILDQPIVQHGPFVETSKDLIYKAFMDYQTASN + " + PFAM_domain complement(8451..8750) + /aSDomain="Pirin" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF02678.19" + /description="Pirin" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0145_0005" + /evalue="1.50E-25" + /label="PAS_chr1-4_0145" + /locus_tag="PAS_chr1-4_0145" + /protein_end="119" + /protein_start="19" + /score="89.4" + /tool="antismash" + /translation="AKVRRSIGSMQMRNFKPFLLLDHFNVDPSAGFPDHPHRGQETITY + MTKGQFAHQDFTSDKVGILNAGDCQIMRAGRGIMHAEMPVQGKSGENIVGMQLWV" + gene complement(<9112..>10335) + /db_xref="GeneID:8197130" + /locus_tag="PAS_chr1-4_0146" + mRNA complement(<9112..>10335) + /db_xref="GeneID:8197130" + /locus_tag="PAS_chr1-4_0146" + /product="Hypothetical protein" + /transcript_id="XM_002490211.1" + CDS complement(9112..10335) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0146" + /db_xref="EnsemblGenomes-Tr:CAY67975" + /db_xref="GeneID:8197130" + /db_xref="GOA:C4QXK2" + /db_xref="InterPro:IPR019038" + /db_xref="UniProtKB/TrEMBL:C4QXK2" + /locus_tag="PAS_chr1-4_0146" + /product="Hypothetical protein" + /protein_id="XP_002490256.1" + /transl_table=1 + /translation="MTQIASYLATKLYEEKLPVTYRMLSRELSIDVRRSKEELAEFYKK + DEKLEIIYAVSGIKNGLDIKLVGKQDLETVKQGYEKVLSVACYSLSTSGVGAQEVANME + GMRRNEWLNAELQRKLGIIESPFHKEQPAEQIEHVEEQWPKVDVVKQPAPKHSPDPKSQ + SPKPPKKTETIPSITSKYVSRKPQNSKSSASVQKTIPTSKAKPNSKSKISYVSRKEPKE + SIVAGDIEDDNSFPLNEPPRKKTTEEINKERQELAAMFTDSDDEMQDTQVIQEESAPPK + NEDSLFVIDDDEDEGGDQAHAREDANPVDQMDVDLASDFDTSIQEVNPPVASNEPSQNE + VEQSKEAITSYVDEDGFITTVKNTKISTDKSSNPKSSSSKPSPTVGTVKGKSSKKAQST + LLSFFGKK" + PFAM_domain complement(9115..10281) + /aSDomain="CDC27" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF09507.13" + /db_xref="GO:0005634" + /db_xref="GO:0006260" + /db_xref="GO:0043625" + /description="DNA polymerase subunit Cdc27" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0146_0007" + /evalue="3.70E-11" + /gene_ontologies="GO:0005634: nucleus" + /gene_ontologies="GO:0006260: DNA replication" + /gene_ontologies="GO:0043625: delta DNA polymerase complex" + /label="PAS_chr1-4_0146" + /locus_tag="PAS_chr1-4_0146" + /protein_end="407" + /protein_start="18" + /score="43.2" + /tool="antismash" + /translation="VTYRMLSRELSIDVRRSKEELAEFYKKDEKLEIIYAVSGIKNGLD + IKLVGKQDLETVKQGYEKVLSVACYSLSTSGVGAQEVANMEGMRRNEWLNAELQRKLGI + IESPFHKEQPAEQIEHVEEQWPKVDVVKQPAPKHSPDPKSQSPKPPKKTETIPSITSKY + VSRKPQNSKSSASVQKTIPTSKAKPNSKSKISYVSRKEPKESIVAGDIEDDNSFPLNEP + PRKKTTEEINKERQELAAMFTDSDDEMQDTQVIQEESAPPKNEDSLFVIDDDEDEGGDQ + AHAREDANPVDQMDVDLASDFDTSIQEVNPPVASNEPSQNEVEQSKEAITSYVDEDGFI + TTVKNTKISTDKSSNPKSSSSKPSPTVGTVKGKSSKKAQSTLLSFFGKK" + gene <10871..>12145 + /db_xref="GeneID:8197131" + /locus_tag="PAS_chr1-4_0147" + mRNA <10871..>12145 + /db_xref="GeneID:8197131" + /locus_tag="PAS_chr1-4_0147" + /product="eukaryotic translation initiation factor 3 + subunit" + /transcript_id="XM_002490212.1" + CDS 10871..12145 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0147" + /db_xref="EnsemblGenomes-Tr:CAY67976" + /db_xref="GeneID:8197131" + /db_xref="GOA:C4QXK3" + /db_xref="InterPro:IPR000717" + /db_xref="InterPro:IPR016650" + /db_xref="InterPro:IPR019010" + /db_xref="UniProtKB/TrEMBL:C4QXK3" + /locus_tag="PAS_chr1-4_0147" + /product="eukaryotic translation initiation factor 3 + subunit" + /protein_id="XP_002490257.1" + /transl_table=1 + /translation="MAQLTPAEIEVAKKFDLTSKIIPFLDRHLIYPLIENLDLTYDEKT + IKELSYNLLRDTYMNKFINDLNPDKEISQDVLTKQKEIEAKSEVLEAETKETLNLLSKK + EVQEQLKSDKNHNRRYLESQHGITEDKIHALYEYGQIQYNKGDYVMASDLLANFRILST + NNELNVSSTWGRLACEILLLEWNNALEELSKLRELIDSRTSFNDPLLQLYNRTWVIHWS + LFPYFKTANGLETLCDLFFSSSYLSTIQASCPWVLRYLVVAVISNNSKKLKDLVRVTAQ + ESYQYADPFTNLIKALYLDFDFAQASQHLNDCEVILKTDFFLNNEDENLPLISKKFITN + AKKLIIQVYVKCYGRISLEALSETLNLTKQELKDLIASLDLKNATLDDEKLIINHTSTK + IYQQVSDKVKSLGYKSNQLLENFAK" + PFAM_domain 10916..11296 + /aSDomain="eIF3_N" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF09440.13" + /description="eIF3 subunit 6 N terminal domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0147_0008" + /evalue="3.50E-32" + /label="PAS_chr1-4_0147" + /locus_tag="PAS_chr1-4_0147" + /protein_end="142" + /protein_start="15" + /score="111.7" + /tool="antismash" + /translation="DLTSKIIPFLDRHLIYPLIENLDLTYDEKTIKELSYNLLRDTYMN + KFINDLNPDKEISQDVLTKQKEIEAKSEVLEAETKETLNLLSKKEVQEQLKSDKNHNRR + YLESQHGITEDKIHALYEYGQIQ" + PFAM_domain 11735..12007 + /aSDomain="PCI" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF01399.30" + /description="PCI domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0147_0009" + /evalue="4.00E-05" + /label="PAS_chr1-4_0147" + /locus_tag="PAS_chr1-4_0147" + /protein_end="379" + /protein_start="288" + /score="24.2" + /tool="antismash" + /translation="PFTNLIKALYLDFDFAQASQHLNDCEVILKTDFFLNNEDENLPLI + SKKFITNAKKLIIQVYVKCYGRISLEALSETLNLTKQELKDLIASL" + gene complement(<12213..>12851) + /db_xref="GeneID:8197132" + /locus_tag="PAS_chr1-4_0148" + mRNA complement(<12213..>12851) + /db_xref="GeneID:8197132" + /locus_tag="PAS_chr1-4_0148" + /product="Mitochondrial ribosomal protein of the large + subunit" + /transcript_id="XM_002490213.1" + CDS complement(12213..12851) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0148" + /db_xref="EnsemblGenomes-Tr:CAY67977" + /db_xref="GeneID:8197132" + /db_xref="GOA:C4QXK4" + /db_xref="InterPro:IPR000456" + /db_xref="UniProtKB/TrEMBL:C4QXK4" + /locus_tag="PAS_chr1-4_0148" + /product="Mitochondrial ribosomal protein of the large + subunit" + /protein_id="XP_002490258.1" + /transl_table=1 + /translation="MGLGRSVKHEWAMLRNLASSLIKNESIITTKARAKKTQALVENLI + TKAKKNYDKSLILADIFEPNVTIPKLYNVLKPRYQSRAGGYTRILNLEPRMNDKAPQVI + MELVDNTQREMKLWYTAKIVARLELQNIAINPLTQKNVDKLLHNRENGEEKFREIVEIC + KKEFYSDPKSLENLPRMRNDINTFKKRDHPYKIVPRPVKRNNATVSTSS" + aSDomain complement(12525..12845) + /aSDomain="TIGR00059" + /aSTool="tigrfam" + /description="L17: ribosomal protein bL17" + /detection="hmmscan" + /domain_id="TIGRFam_PAS_chr1-4_0148_0002" + /evalue="4.30E-28" + /identifier="TIGR00059" + /label="PAS_chr1-4_0148" + /locus_tag="PAS_chr1-4_0148" + /protein_end="109" + /protein_start="2" + /score="95.9" + /tool="antismash" + /translation="LGRSVKHEWAMLRNLASSLIKNESIITTKARAKKTQALVENLITK + AKKNYDKSLILADIFEPNVTIPKLYNVLKPRYQSRAGGYTRILNLEPRMNDKAPQVIME + LVD" + PFAM_domain complement(12528..12815) + /aSDomain="Ribosomal_L17" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF01196.22" + /db_xref="GO:0003735" + /db_xref="GO:0005840" + /db_xref="GO:0006412" + /description="Ribosomal protein L17" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0148_0010" + /evalue="1.00E-28" + /gene_ontologies="GO:0003735: structural constituent of + ribosome" + /gene_ontologies="GO:0005840: ribosome" + /gene_ontologies="GO:0006412: translation" + /label="PAS_chr1-4_0148" + /locus_tag="PAS_chr1-4_0148" + /protein_end="108" + /protein_start="12" + /score="100.2" + /tool="antismash" + /translation="MLRNLASSLIKNESIITTKARAKKTQALVENLITKAKKNYDKSLI + LADIFEPNVTIPKLYNVLKPRYQSRAGGYTRILNLEPRMNDKAPQVIMELV" + gene <13073..>13381 + /db_xref="GeneID:8197133" + /locus_tag="PAS_chr1-4_0694" + mRNA <13073..>13381 + /db_xref="GeneID:8197133" + /locus_tag="PAS_chr1-4_0694" + /product="uncharacterized protein" + /transcript_id="XM_002490214.1" + CDS 13073..13381 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0694" + /db_xref="EnsemblGenomes-Tr:CAY67978" + /db_xref="GeneID:8197133" + /db_xref="UniProtKB/TrEMBL:C4QXK5" + /locus_tag="PAS_chr1-4_0694" + /product="uncharacterized protein" + /protein_id="XP_002490259.1" + /transl_table=1 + /translation="MGGRIYGFLAGALFTSSLTYLAREQFQSDQVRISTRLRSYQKLIN + EGDQLKLTDNKLEYQTRPWKEAFKDLWNEEVIKTVNRIYSIRWYEDAKYLVDKVEGK" + PFAM_domain 13163..13336 + /aSDomain="AIM5" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF17050.8" + /db_xref="GO:0042407" + /db_xref="GO:0044284" + /db_xref="GO:0061617" + /description="Altered inheritance of mitochondria 5" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0694_0011" + /evalue="3.20E-10" + /gene_ontologies="GO:0042407: cristae formation" + /gene_ontologies="GO:0044284: mitochondrial crista + junction" + /gene_ontologies="GO:0061617: MICOS complex" + /label="PAS_chr1-4_0694" + /locus_tag="PAS_chr1-4_0694" + /protein_end="88" + /protein_start="30" + /score="40.7" + /tool="antismash" + /translation="VRISTRLRSYQKLINEGDQLKLTDNKLEYQTRPWKEAFKDLWNEE + VIKTVNRIYSIRW" + gene complement(<13401..>14441) + /db_xref="GeneID:8197438" + /locus_tag="PAS_chr1-4_0149" + mRNA complement(<13401..>14441) + /db_xref="GeneID:8197438" + /locus_tag="PAS_chr1-4_0149" + /product="3-ketosphinganine reductase, catalyzes the second + step in phytosphingosine synthesis" + /transcript_id="XM_002490215.1" + CDS complement(13401..14441) + /NRPS_PKS="Domain: PKS_KR (42-206). E-value: 1.9e-08. + Score: 26.3. Matches aSDomain: + nrpspksdomains_PAS_chr1-4_0149_PKS_KR.1" + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0149" + /db_xref="EnsemblGenomes-Tr:CAY67979" + /db_xref="GeneID:8197438" + /db_xref="GOA:C4QXK6" + /db_xref="InterPro:IPR002198" + /db_xref="InterPro:IPR002347" + /db_xref="InterPro:IPR016040" + /db_xref="UniProtKB/TrEMBL:C4QXK6" + /gene_functions="biosynthetic-additional (smcogs) + SMCOG1001:short-chain dehydrogenase/reductase SDR (Score: + 105.5; E-value: 5.4e-32)" + /gene_kind="biosynthetic-additional" + /locus_tag="PAS_chr1-4_0149" + /product="3-ketosphinganine reductase, catalyzes the second + step in phytosphingosine synthesis" + /protein_id="XP_002490260.1" + /transl_table=1 + /translation="MILVHDTTLSSNIWCTISAIILIQSVEGTGMFDNFDVTNKKAIIT + GASQGVGAEFAKLLYGKGCSVVIVARTESLLKQVVKDAIDIHGTEKGNTISYVAADISK + YDQCERVLEEVGFSPDIVFCCAGSSIPGLFLELDEKTLSSGIDINYKTALYFSHVALKV + MTKVEKPYKRHLVFFSSVLAFYSFIGYGQYAPMKAALRSLSDILRQEVSIHNIKVECIF + PGNTLSEGFLEEEKSKPEITRIIEGPSSPISTEQCCKIIYNALQSGYQYVTTDFIGYVL + MSASLGGSPRYYGVIQVIISFLFSIFAPIASMFVNKQIRDYFKKQSRISPSSSSSPSPE + REQKDK" + PFAM_domain complement(13752..14324) + /aSDomain="adh_short" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00106.28" + /description="short chain dehydrogenase" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0149_0012" + /evalue="4.30E-30" + /label="PAS_chr1-4_0149" + /locus_tag="PAS_chr1-4_0149" + /protein_end="230" + /protein_start="39" + /score="104.8" + /tool="antismash" + /translation="KKAIITGASQGVGAEFAKLLYGKGCSVVIVARTESLLKQVVKDAI + DIHGTEKGNTISYVAADISKYDQCERVLEEVGFSPDIVFCCAGSSIPGLFLELDEKTLS + SGIDINYKTALYFSHVALKVMTKVEKPYKRHLVFFSSVLAFYSFIGYGQYAPMKAALRS + LSDILRQEVSIHNIKVECIFPGNTLSEG" + aSDomain complement(13824..14315) + /aSDomain="PKS_KR" + /aSTool="nrps_pks_domains" + /database="nrpspksdomains.hmm" + /detection="hmmscan" + /domain_id="nrpspksdomains_PAS_chr1-4_0149_PKS_KR.1" + /evalue="1.90E-08" + /label="PAS_chr1-4_0149_PKS_KR.1" + /locus_tag="PAS_chr1-4_0149" + /protein_end="206" + /protein_start="42" + /score="26.3" + /specificity="KR activity: inactive" + /specificity="KR stereochemistry: C2" + /tool="antismash" + /translation="IITGASQGVGAEFAKLLYGKGCSVVIVARTESLLKQVVKDAIDIH + GTEKGNTISYVAADISKYDQCERVLEEVGFSPDIVFCCAGSSIPGLFLELDEKTLSSGI + DINYKTALYFSHVALKVMTKVEKPYKRHLVFFSSVLAFYSFIGYGQYAPMKAALRSLSD + I" + gene <15004..>17043 + /db_xref="GeneID:8197134" + /locus_tag="PAS_chr1-4_0150" + mRNA <15004..>17043 + /db_xref="GeneID:8197134" + /locus_tag="PAS_chr1-4_0150" + /product="Transketolase, similar to Tkl2p" + /transcript_id="XM_002490216.1" + CDS 15004..17043 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0150" + /db_xref="EnsemblGenomes-Tr:CAY67980" + /db_xref="GeneID:8197134" + /db_xref="GOA:C4QXK7" + /db_xref="InterPro:IPR005474" + /db_xref="InterPro:IPR005475" + /db_xref="InterPro:IPR005476" + /db_xref="InterPro:IPR005478" + /db_xref="InterPro:IPR009014" + /db_xref="InterPro:IPR020826" + /db_xref="InterPro:IPR029061" + /db_xref="UniProtKB/TrEMBL:C4QXK7" + /gene_functions="biosynthetic-additional (smcogs) + SMCOG1204:transketolase (Score: 643.7; E-value: 6.2e-195)" + /gene_kind="biosynthetic-additional" + /locus_tag="PAS_chr1-4_0150" + /product="Transketolase, similar to Tkl2p" + /protein_id="XP_002490261.1" + /transl_table=1 + /translation="MSDLLAINTIRLLAVDTVAKANSGHPGAPMGLAPAAHTLFKQMRF + NPRNPAWINRDRFVLSNGHACALLYTMLFLYGYDYTIDDLKSFRQLNSKTPGHPEAELP + GVEVTTGPLGQGIANAVGLAIAQAQLAATYNKPNYELFSNYTYAFLGDGCLQEGVAQEA + ISLAGHLGDGLKLIAFWDDNQISIDGDTNVSFTEDVPAKFRAQGWEVLSVKDGNDDLEG + IAAALAKAKTTNKPTLIRLPTIIGYGSLQQGTHGVHGSPLKPDDIKQLKKKFGFDPEQN + FVVPREVTESYAKHVADNQQVEVEWNKLLTAYTKEYPELGQELHRRLDGKLPENWQKAL + PTYTVDDKPVASRKLSEIVLTSIEKELPELVGGSADLTGSNLTRWPDAVDFQPKSTGLG + DFSGRYFRFGVREHGMGAIINGISAYGANFKAYGGTFLNFVSYASGAVRLSALSGHPII + WVATHDSIGLGEDGPTHQPIETLAHLRALPNLMVWRPADGNETSAAYLRAIESKHTPSI + IALTRQNLPQLEHSSIEKAAKGGYTVYPVENPDIILVASGSEVSIAIDGAKKLGTEGVK + ASVVSIPDFFTFDSQARSYQLSVLPDGVPIMSVEVMSTFGWSKYSHEQFGINRFGISGP + GPEIYKFFEFTAEGVADRASKVVQFYKGKELLSPLNKAFESVHA" + PFAM_domain 15016..16002 + /aSDomain="Transketolase_N" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00456.24" + /description="Transketolase, thiamine diphosphate binding + domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0150_0013" + /evalue="6.30E-150" + /label="PAS_chr1-4_0150" + /locus_tag="PAS_chr1-4_0150" + /protein_end="333" + /protein_start="4" + /score="498.9" + /tool="antismash" + /translation="LAINTIRLLAVDTVAKANSGHPGAPMGLAPAAHTLFKQMRFNPRN + PAWINRDRFVLSNGHACALLYTMLFLYGYDYTIDDLKSFRQLNSKTPGHPEAELPGVEV + TTGPLGQGIANAVGLAIAQAQLAATYNKPNYELFSNYTYAFLGDGCLQEGVAQEAISLA + GHLGDGLKLIAFWDDNQISIDGDTNVSFTEDVPAKFRAQGWEVLSVKDGNDDLEGIAAA + LAKAKTTNKPTLIRLPTIIGYGSLQQGTHGVHGSPLKPDDIKQLKKKFGFDPEQNFVVP + REVTESYAKHVADNQQVEVEWNKLLTAYTKEYPELGQELHRRLDGKLP" + aSDomain 15019..16977 + /aSDomain="TIGR00232" + /aSTool="tigrfam" + /description="tktlase_bact: transketolase" + /detection="hmmscan" + /domain_id="TIGRFam_PAS_chr1-4_0150_0003" + /evalue="3.90E-277" + /identifier="TIGR00232" + /label="PAS_chr1-4_0150" + /locus_tag="PAS_chr1-4_0150" + /protein_end="658" + /protein_start="5" + /score="918.9" + /tool="antismash" + /translation="AINTIRLLAVDTVAKANSGHPGAPMGLAPAAHTLFKQMRFNPRNP + AWINRDRFVLSNGHACALLYTMLFLYGYDYTIDDLKSFRQLNSKTPGHPEAELPGVEVT + TGPLGQGIANAVGLAIAQAQLAATYNKPNYELFSNYTYAFLGDGCLQEGVAQEAISLAG + HLGDGLKLIAFWDDNQISIDGDTNVSFTEDVPAKFRAQGWEVLSVKDGNDDLEGIAAAL + AKAKTTNKPTLIRLPTIIGYGSLQQGTHGVHGSPLKPDDIKQLKKKFGFDPEQNFVVPR + EVTESYAKHVADNQQVEVEWNKLLTAYTKEYPELGQELHRRLDGKLPENWQKALPTYTV + DDKPVASRKLSEIVLTSIEKELPELVGGSADLTGSNLTRWPDAVDFQPKSTGLGDFSGR + YFRFGVREHGMGAIINGISAYGANFKAYGGTFLNFVSYASGAVRLSALSGHPIIWVATH + DSIGLGEDGPTHQPIETLAHLRALPNLMVWRPADGNETSAAYLRAIESKHTPSIIALTR + QNLPQLEHSSIEKAAKGGYTVYPVENPDIILVASGSEVSIAIDGAKKLGTEGVKASVVS + IPDFFTFDSQARSYQLSVLPDGVPIMSVEVMSTFGWSKYSHEQFGINRFGISGPGPEIY + KFFEFTAEGVADRASKVV" + PFAM_domain 16048..16581 + /aSDomain="Transket_pyr" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF02779.27" + /description="Transketolase, pyrimidine binding domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0150_0014" + /evalue="7.70E-45" + /label="PAS_chr1-4_0150" + /locus_tag="PAS_chr1-4_0150" + /protein_end="526" + /protein_start="348" + /score="152.9" + /tool="antismash" + /translation="PVASRKLSEIVLTSIEKELPELVGGSADLTGSNLTRWPDAVDFQP + KSTGLGDFSGRYFRFGVREHGMGAIINGISAYGANFKAYGGTFLNFVSYASGAVRLSAL + SGHPIIWVATHDSIGLGEDGPTHQPIETLAHLRALPNLMVWRPADGNETSAAYLRAIES + KHTPSIIALTRQNLP" + PFAM_domain 16621..16953 + /aSDomain="Transketolase_C" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF02780.23" + /description="Transketolase, C-terminal domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0150_0015" + /evalue="4.90E-09" + /label="PAS_chr1-4_0150" + /locus_tag="PAS_chr1-4_0150" + /protein_end="650" + /protein_start="539" + /score="36.2" + /tool="antismash" + /translation="GYTVYPVENPDIILVASGSEVSIAIDGAKKLGTEGVKASVVSIPD + FFTFDSQARSYQLSVLPDGVPIMSVEVMSTFGWSKYSHEQFGINRFGISGPGPEIYKFF + EFTAEGV" + gene <17228..>17698 + /db_xref="GeneID:8197135" + /locus_tag="PAS_chr1-4_0151" + mRNA <17228..>17698 + /db_xref="GeneID:8197135" + /locus_tag="PAS_chr1-4_0151" + /product="Protein phosphotyrosine phosphatase" + /transcript_id="XM_002490217.1" + CDS 17228..17698 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0151" + /db_xref="EnsemblGenomes-Tr:CAY67981" + /db_xref="GeneID:8197135" + /db_xref="GOA:C4QXK8" + /db_xref="InterPro:IPR000106" + /db_xref="InterPro:IPR002115" + /db_xref="InterPro:IPR017867" + /db_xref="InterPro:IPR023485" + /db_xref="UniProtKB/TrEMBL:C4QXK8" + /locus_tag="PAS_chr1-4_0151" + /product="Protein phosphotyrosine phosphatase" + /protein_id="XP_002490262.1" + /transl_table=1 + /translation="MAPISVAFVCLGNICRSPMAEAVFTHLVKEKGLDSKFKKIDSFGT + SGYHIDDTPDHRSVACCKKHGVPVNHRGQQISPDDFYHFDYILAMDESNLSNLKRIQPK + DSNAVVRLFGDYRTDKSFHRIVEDPYYGGSSGFERNFKQITHFSEEFLNKEL" + PFAM_domain 17243..17683 + /aSDomain="LMWPc" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF01451.24" + /description="Low molecular weight phosphotyrosine protein + phosphatase" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0151_0016" + /evalue="5.20E-46" + /label="PAS_chr1-4_0151" + /locus_tag="PAS_chr1-4_0151" + /protein_end="152" + /protein_start="5" + /score="156.7" + /tool="antismash" + /translation="VAFVCLGNICRSPMAEAVFTHLVKEKGLDSKFKKIDSFGTSGYHI + DDTPDHRSVACCKKHGVPVNHRGQQISPDDFYHFDYILAMDESNLSNLKRIQPKDSNAV + VRLFGDYRTDKSFHRIVEDPYYGGSSGFERNFKQITHFSEEFL" + gene complement(<17718..>19684) + /db_xref="GeneID:8197136" + /locus_tag="PAS_chr1-4_0152" + mRNA complement(join(<17718..19557,19662..>19684)) + /db_xref="GeneID:8197136" + /locus_tag="PAS_chr1-4_0152" + /product="Subunit of the CCR4-NOT complex, which is a + global transcriptional regulator with roles in transcrip" + /transcript_id="XM_002490218.1" + CDS complement(join(17718..19557,19662..19684)) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0152" + /db_xref="EnsemblGenomes-Tr:CAY67982" + /db_xref="GeneID:8197136" + /db_xref="GOA:C4QXK9" + /db_xref="InterPro:IPR007207" + /db_xref="InterPro:IPR007282" + /db_xref="InterPro:IPR012270" + /db_xref="UniProtKB/TrEMBL:C4QXK9" + /locus_tag="PAS_chr1-4_0152" + /product="Subunit of the CCR4-NOT complex, which is a + global transcriptional regulator with roles in transcrip" + /protein_id="XP_002490263.1" + /transl_table=1 + /translation="MSQRKLQQEIDRVFKKVKEGLEEFDYVYDKLQACESSSQKEKLES + DLKREIKKLQRSRDQIKIWLAGNEVKEKKGLMEHRKLIEHEMERFKEVEKEMKTKAFSK + EGLNMNKVDPREKEKSETSKFVESMIEELERQSEALEAQIDQIQSSGKRGKKLDNSKTD + QIAELQSSLDRNNWHQEKLQTILRLLQNGNLEADQIQRIQEDIEYYVESNQDADFAEDD + GIYDELGLDEIEDGFLFAAASGPLSKDEEGKDENDENVSDNESPSASASSNFAAVNQGS + TSDSTVKTAPAAINSSTGSVSNVTSTNSNASVLLNKLTRTSPARSAAATPPHSHNELTG + IQSNLKPAVAPVLTPKLKYSKVASTAATASVPPGSTKVGSSTHSTTPTATTAATAHPAV + SSSSLPLDSLSSTTTHPNGLDAPTSESSLKIANNLIANLDGVKKECLNKPIKKTPEEMD + NMYQLLNSSLLNCPDSFDADVPNMYIPRQPHPTHISFPQEPLLEIMNSAKILQNFDLET + LFYCFYYHSYENAADEHKVFDNSGSFLQINTAKELHRRGWKYHKELKTWFLLNNDEANQ + TPPPIEEHVQQKSNWKYFDYQETWLPRRKDDFTFEKDKLETLYL" + PFAM_domain complement(17736..18185) + /aSDomain="NOT2_3_5" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF04153.21" + /db_xref="GO:0006355" + /description="NOT2 / NOT3 / NOT5 family" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0152_0018" + /evalue="5.60E-44" + /gene_ontologies="GO:0006355: regulation of DNA-templated + transcription" + /label="PAS_chr1-4_0152" + /locus_tag="PAS_chr1-4_0152" + /protein_end="615" + /protein_start="465" + /score="149.5" + /tool="antismash" + /translation="SSLLNCPDSFDADVPNMYIPRQPHPTHISFPQEPLLEIMNSAKIL + QNFDLETLFYCFYYHSYENAADEHKVFDNSGSFLQINTAKELHRRGWKYHKELKTWFLL + NNDEANQTPPPIEEHVQQKSNWKYFDYQETWLPRRKDDFTFEKDKL" + PFAM_domain complement(join(18888..19557,19662..19681)) + /aSDomain="Not3" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF04065.18" + /db_xref="GO:0005634" + /db_xref="GO:0006355" + /description="Not1 N-terminal domain, CCR4-Not complex + component" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0152_0017" + /evalue="1.30E-89" + /gene_ontologies="GO:0005634: nucleus" + /gene_ontologies="GO:0006355: regulation of DNA-templated + transcription" + /label="PAS_chr1-4_0152" + /locus_tag="PAS_chr1-4_0152" + /protein_end="231" + /protein_start="1" + /score="299.7" + /tool="antismash" + /translation="SQRKLQQEIDRVFKKVKEGLEEFDYVYDKLQACESSSQKEKLESD + LKREIKKLQRSRDQIKIWLAGNEVKEKKGLMEHRKLIEHEMERFKEVEKEMKTKAFSKE + GLNMNKVDPREKEKSETSKFVESMIEELERQSEALEAQIDQIQSSGKRGKKLDNSKTDQ + IAELQSSLDRNNWHQEKLQTILRLLQNGNLEADQIQRIQEDIEYYVESNQDADFAEDDG + IYDELGLD" + gene <20001..>24203 + /db_xref="GeneID:8197137" + /locus_tag="PAS_chr1-4_0153" + mRNA <20001..>24203 + /db_xref="GeneID:8197137" + /locus_tag="PAS_chr1-4_0153" + /product="Alpha aminoadipate reductase" + /transcript_id="XM_002490219.1" + CDS 20001..24203 + /NRPS_PKS="Domain: AMP-binding (250-716). E-value: 1.3e-72. + Score: 236.5. Matches aSDomain: + nrpspksdomains_PAS_chr1-4_0153_AMP-binding.1" + /NRPS_PKS="Domain: PCP (859-928). E-value: 1.4e-17. Score: + 55.6. Matches aSDomain: + nrpspksdomains_PAS_chr1-4_0153_PCP.1" + /NRPS_PKS="Domain: NAD_binding_4 (987-1234). E-value: + 4.7e-77. Score: 250.3. Matches aSDomain: + nrpspksdomains_PAS_chr1-4_0153_NAD_binding_4.1" + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0153" + /db_xref="EnsemblGenomes-Tr:CAY67983" + /db_xref="GeneID:8197137" + /db_xref="GOA:C4QXL0" + /db_xref="InterPro:IPR000873" + /db_xref="InterPro:IPR006162" + /db_xref="InterPro:IPR009081" + /db_xref="InterPro:IPR010071" + /db_xref="InterPro:IPR010080" + /db_xref="InterPro:IPR013120" + /db_xref="InterPro:IPR014397" + /db_xref="InterPro:IPR016040" + /db_xref="InterPro:IPR020845" + /db_xref="InterPro:IPR025110" + /db_xref="UniProtKB/TrEMBL:C4QXL0" + /gene_functions="biosynthetic (rule-based-clusters) + NRPS-like: PP-binding" + /gene_functions="biosynthetic (rule-based-clusters) + NRPS-like: AMP-binding" + /gene_functions="biosynthetic (rule-based-clusters) + NRPS-like: NAD_binding_4" + /gene_functions="biosynthetic-additional (smcogs) + SMCOG1002:AMP-dependent synthetase and ligase (Score: 239; + E-value: 1.3e-72)" + /gene_kind="biosynthetic" + /locus_tag="PAS_chr1-4_0153" + /product="Alpha aminoadipate reductase" + /protein_id="XP_002490264.1" + /sec_met_domain="AMP-binding (E-value: 5.8e-98, bitscore: + 324.7, seeds: 400, tool: rule-based-clusters)" + /sec_met_domain="PP-binding (E-value: 1.5e-15, bitscore: + 54.0, seeds: 164, tool: rule-based-clusters)" + /sec_met_domain="NAD_binding_4 (E-value: 1.3e-75, bitscore: + 250.3, seeds: 102, tool: rule-based-clusters)" + /transl_table=1 + /translation="MSEENLNYWANILDGPTLSVLPRDYNRPVAGKVIEANKTFDISDI + LPFLNKANEPSVTQFTAPLAVFAVLVYRLTGDDDIVILTDSPKKQNLPFVVRLQVDPSK + SFVDVSKQVGEQYLESLERATPLKDIVTHLKESKQLPNYPPIFRLSFQTAKKVQQLSTL + VEGSTRDLAIFLENNTSINIYYNSLLYTHNRIAYFSQQFSSFIDEVNKAPETPIGKISL + LTEQQSKLLPDPTANLDWSGYRGAIQDIFSDNAEKFPDRTCVVETKSFLNPNSQTRTFT + YKQIDQASNIVGNYLVHTGIKRGDVVMIYAYRGVDLMVAVMGVLKAGATFSVIDPAYPP + ARQNVYLQVAKPAGLIVLEKAGVLDQLVEDYIKNELSLVSRISNLKIEADGNVLGGDVD + GKDALYDYQQFKTRRTGVLVGPDSNPTLSFTSGSEGIPKGVLGRHFSLAYYFPWMSKTF + NLSENDKFTMLSGIAHDPIQRDMFTPLFLGAQLLIPTSDDIGTPGKLAEWMQTYGATVT + HLTPAMGQLLSAQATKEIPSLHHAFFVGDILTKRDCLRLQTIAQNVNIINMYGTTETQR + AVSYFEIPSRAQDSTFLEVQKDIMPAGKGMHNVQLLVVNRHDRSKTCAIGEVGEIYVRA + AGLAEQYRGQPDLNKEKFVPNWFVSPSKWVEEDKKISKDEPWREFYLGPRDRLYRTGDL + GRYLPTGDCEVSGRADDQVKIRGFRIELGEIDTHISRHPLIRQNVTLVRRDKDEEPILI + SYVVPKETPELENFKSSSDDLDDLNDPIVKSLLLYRELIKDLKAHLKKTLASYAIPTII + VPMAKLPLNPNGKVDKPKLPFPDTVQLAAVAQKSSAEVDDSEFTTTELQIKDLWLQVLP + NPPASISLEDSFFDLGGHSILATRMIFELRRKLAVDLPLGTIFKHPTVKLFAAEVDRVK + NGDEVQFADNKQESTSAGSDEQVVDYFQDAKDLVSSQLLDSYKSRLALSNAELINIFLT + GATGFLGSYILKDLLERDLDVQVYAHVRAKDEESGLERLRNTGKVYGIWNEEWTSRIKV + VIADLSKDKLGLSGEKYAELANTIDLIIHNGALVHWVYPYSKLRDANVISTINVLNLAA + SGKPKQFGFVSSTSTLDTEHYITLSDTLTEQGEDGIPESDDLLGSSKGLGTGYGQSKWA + AEYIIRRAFERGLRGAIIRPGYVTGHSRTGACNTDDFLLRMLKGCAELGKLPNISNTVN + MVPVDHVALVVTASSLHPTAEEGHCVVQVTGHPRIRFNEFLNALNDYGYEVKLTDYVEW + KRDLERFVVDQSKDSALYPLLHFVLDNLPQDTKAPELDDKNAKDILSGDTRWTGYDGSK + GRGVDSAQTGIYIAYLIKTGFLPPPSKEGKKPLPEIEISEESLKLIKEGAGARTSAA" + PFAM_domain 20007..20690 + /aSDomain="Condensation" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00668.23" + /db_xref="GO:0003824" + /description="Condensation domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0153_0019" + /evalue="3.30E-13" + /gene_ontologies="GO:0003824: catalytic activity" + /label="PAS_chr1-4_0153" + /locus_tag="PAS_chr1-4_0153" + /protein_end="230" + /protein_start="2" + /score="49.2" + /tool="antismash" + /translation="EENLNYWANILDGPTLSVLPRDYNRPVAGKVIEANKTFDISDILP + FLNKANEPSVTQFTAPLAVFAVLVYRLTGDDDIVILTDSPKKQNLPFVVRLQVDPSKSF + VDVSKQVGEQYLESLERATPLKDIVTHLKESKQLPNYPPIFRLSFQTAKKVQQLSTLVE + GSTRDLAIFLENNTSINIYYNSLLYTHNRIAYFSQQFSSFIDEVNKAPETPIGKISLLT + EQQSKL" + aSDomain 20025..24200 + /aSDomain="TIGR03443" + /aSTool="tigrfam" + /description="alpha_am_amid: L-aminoadipate-semialdehyde + dehydrogenase" + /detection="hmmscan" + /domain_id="TIGRFam_PAS_chr1-4_0153_0004" + /evalue="0.00E+00" + /identifier="TIGR03443" + /label="PAS_chr1-4_0153" + /locus_tag="PAS_chr1-4_0153" + /protein_end="1400" + /protein_start="8" + /score="2297.0" + /tool="antismash" + /translation="WANILDGPTLSVLPRDYNRPVAGKVIEANKTFDISDILPFLNKAN + EPSVTQFTAPLAVFAVLVYRLTGDDDIVILTDSPKKQNLPFVVRLQVDPSKSFVDVSKQ + VGEQYLESLERATPLKDIVTHLKESKQLPNYPPIFRLSFQTAKKVQQLSTLVEGSTRDL + AIFLENNTSINIYYNSLLYTHNRIAYFSQQFSSFIDEVNKAPETPIGKISLLTEQQSKL + LPDPTANLDWSGYRGAIQDIFSDNAEKFPDRTCVVETKSFLNPNSQTRTFTYKQIDQAS + NIVGNYLVHTGIKRGDVVMIYAYRGVDLMVAVMGVLKAGATFSVIDPAYPPARQNVYLQ + VAKPAGLIVLEKAGVLDQLVEDYIKNELSLVSRISNLKIEADGNVLGGDVDGKDALYDY + QQFKTRRTGVLVGPDSNPTLSFTSGSEGIPKGVLGRHFSLAYYFPWMSKTFNLSENDKF + TMLSGIAHDPIQRDMFTPLFLGAQLLIPTSDDIGTPGKLAEWMQTYGATVTHLTPAMGQ + LLSAQATKEIPSLHHAFFVGDILTKRDCLRLQTIAQNVNIINMYGTTETQRAVSYFEIP + SRAQDSTFLEVQKDIMPAGKGMHNVQLLVVNRHDRSKTCAIGEVGEIYVRAAGLAEQYR + GQPDLNKEKFVPNWFVSPSKWVEEDKKISKDEPWREFYLGPRDRLYRTGDLGRYLPTGD + CEVSGRADDQVKIRGFRIELGEIDTHISRHPLIRQNVTLVRRDKDEEPILISYVVPKET + PELENFKSSSDDLDDLNDPIVKSLLLYRELIKDLKAHLKKTLASYAIPTIIVPMAKLPL + NPNGKVDKPKLPFPDTVQLAAVAQKSSAEVDDSEFTTTELQIKDLWLQVLPNPPASISL + EDSFFDLGGHSILATRMIFELRRKLAVDLPLGTIFKHPTVKLFAAEVDRVKNGDEVQFA + DNKQESTSAGSDEQVVDYFQDAKDLVSSQLLDSYKSRLALSNAELINIFLTGATGFLGS + YILKDLLERDLDVQVYAHVRAKDEESGLERLRNTGKVYGIWNEEWTSRIKVVIADLSKD + KLGLSGEKYAELANTIDLIIHNGALVHWVYPYSKLRDANVISTINVLNLAASGKPKQFG + FVSSTSTLDTEHYITLSDTLTEQGEDGIPESDDLLGSSKGLGTGYGQSKWAAEYIIRRA + FERGLRGAIIRPGYVTGHSRTGACNTDDFLLRMLKGCAELGKLPNISNTVNMVPVDHVA + LVVTASSLHPTAEEGHCVVQVTGHPRIRFNEFLNALNDYGYEVKLTDYVEWKRDLERFV + VDQSKDSALYPLLHFVLDNLPQDTKAPELDDKNAKDILSGDTRWTGYDGSKGRGVDSAQ + TGIYIAYLIKTGFLPPPSKEGKKPLPEIEISEESLKLIKEGAGARTSAA" + aSDomain 20751..22148 + /aSDomain="AMP-binding" + /aSTool="nrps_pks_domains" + /database="nrpspksdomains.hmm" + /detection="hmmscan" + /domain_id="nrpspksdomains_PAS_chr1-4_0153_AMP-binding.1" + /evalue="1.30E-72" + /label="PAS_chr1-4_0153_AMP-binding.1" + /locus_tag="PAS_chr1-4_0153" + /protein_end="716" + /protein_start="250" + /score="236.5" + /specificity="substrate consensus: Aad" + /tool="antismash" + /translation="FSDNAEKFPDRTCVVETKSFLNPNSQTRTFTYKQIDQASNIVGNY + LVHTGIKRGDVVMIYAYRGVDLMVAVMGVLKAGATFSVIDPAYPPARQNVYLQVAKPAG + LIVLEKAGVLDQLVEDYIKNELSLVSRISNLKIEADGNVLGGDVDGKDALYDYQQFKTR + RTGVLVGPDSNPTLSFTSGSEGIPKGVLGRHFSLAYYFPWMSKTFNLSENDKFTMLSGI + AHDPIQRDMFTPLFLGAQLLIPTSDDIGTPGKLAEWMQTYGATVTHLTPAMGQLLSAQA + TKEIPSLHHAFFVGDILTKRDCLRLQTIAQNVNIINMYGTTETQRAVSYFEIPSRAQDS + TFLEVQKDIMPAGKGMHNVQLLVVNRHDRSKTCAIGEVGEIYVRAAGLAEQYRGQPDLN + KEKFVPNWFVSPSKWVEEDKKISKDEPWREFYLGPRDRLYRTGDLGRYLPTGDCEVSGR + ADDQVKIR" + PFAM_domain 20751..22148 + /aSDomain="AMP-binding" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00501.31" + /description="AMP-binding enzyme" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0153_0020" + /evalue="7.60E-67" + /label="PAS_chr1-4_0153" + /locus_tag="PAS_chr1-4_0153" + /protein_end="716" + /protein_start="250" + /score="225.9" + /tool="antismash" + /translation="FSDNAEKFPDRTCVVETKSFLNPNSQTRTFTYKQIDQASNIVGNY + LVHTGIKRGDVVMIYAYRGVDLMVAVMGVLKAGATFSVIDPAYPPARQNVYLQVAKPAG + LIVLEKAGVLDQLVEDYIKNELSLVSRISNLKIEADGNVLGGDVDGKDALYDYQQFKTR + RTGVLVGPDSNPTLSFTSGSEGIPKGVLGRHFSLAYYFPWMSKTFNLSENDKFTMLSGI + AHDPIQRDMFTPLFLGAQLLIPTSDDIGTPGKLAEWMQTYGATVTHLTPAMGQLLSAQA + TKEIPSLHHAFFVGDILTKRDCLRLQTIAQNVNIINMYGTTETQRAVSYFEIPSRAQDS + TFLEVQKDIMPAGKGMHNVQLLVVNRHDRSKTCAIGEVGEIYVRAAGLAEQYRGQPDLN + KEKFVPNWFVSPSKWVEEDKKISKDEPWREFYLGPRDRLYRTGDLGRYLPTGDCEVSGR + ADDQVKIR" + aSModule 20751..23702 + /complete + /domains="nrpspksdomains_PAS_chr1-4_0153_AMP-binding.1" + /domains="nrpspksdomains_PAS_chr1-4_0153_PCP.1" + /domains="nrpspksdomains_PAS_chr1-4_0153_NAD_binding_4.1" + /locus_tags="PAS_chr1-4_0153" + /monomer_pairings="Aad -> Aad" + /starter_module + /tool="antismash" + /type="nrps" + aSDomain 20841..22217 + /aSDomain="TIGR01733" + /aSTool="tigrfam" + /description="AA-adenyl-dom: amino acid adenylation domain" + /detection="hmmscan" + /domain_id="TIGRFam_PAS_chr1-4_0153_0005" + /evalue="2.00E-114" + /identifier="TIGR01733" + /label="PAS_chr1-4_0153" + /locus_tag="PAS_chr1-4_0153" + /protein_end="739" + /protein_start="280" + /score="380.6" + /tool="antismash" + /translation="TYKQIDQASNIVGNYLVHTGIKRGDVVMIYAYRGVDLMVAVMGVL + KAGATFSVIDPAYPPARQNVYLQVAKPAGLIVLEKAGVLDQLVEDYIKNELSLVSRISN + LKIEADGNVLGGDVDGKDALYDYQQFKTRRTGVLVGPDSNPTLSFTSGSEGIPKGVLGR + HFSLAYYFPWMSKTFNLSENDKFTMLSGIAHDPIQRDMFTPLFLGAQLLIPTSDDIGTP + GKLAEWMQTYGATVTHLTPAMGQLLSAQATKEIPSLHHAFFVGDILTKRDCLRLQTIAQ + NVNIINMYGTTETQRAVSYFEIPSRAQDSTFLEVQKDIMPAGKGMHNVQLLVVNRHDRS + KTCAIGEVGEIYVRAAGLAEQYRGQPDLNKEKFVPNWFVSPSKWVEEDKKISKDEPWRE + FYLGPRDRLYRTGDLGRYLPTGDCEVSGRADDQVKIRGFRIELGEIDTHISRHPLIRQN + V" + CDS_motif 21285..21332 + /aSTool="nrps_pks_domains" + /database="abmotifs" + /detection="hmmscan" + /domain_id="nrpspksmotif_PAS_chr1-4_0153_0001" + /evalue="8.40E-04" + /label="NRPS-A_a3" + /locus_tag="PAS_chr1-4_0153" + /protein_end="444" + /protein_start="428" + /score="12.4" + /tool="antismash" + /translation="FTSGSEGIPKGVLGRH" + CDS_motif 21474..21506 + /aSTool="nrps_pks_domains" + /database="abmotifs" + /detection="hmmscan" + /domain_id="nrpspksmotif_PAS_chr1-4_0153_0002" + /evalue="3.00E+01" + /label="NRPS-A_a3" + /locus_tag="PAS_chr1-4_0153" + /protein_end="502" + /protein_start="491" + /score="-1.4" + /tool="antismash" + /translation="LIPTSDDIGTP" + CDS_motif 21873..21959 + /aSTool="nrps_pks_domains" + /database="abmotifs" + /detection="hmmscan" + /domain_id="nrpspksmotif_PAS_chr1-4_0153_0003" + /evalue="1.90E-07" + /label="NRPS-A_a6" + /locus_tag="PAS_chr1-4_0153" + /protein_end="653" + /protein_start="624" + /score="23.4" + /tool="antismash" + /translation="IGEVGEIYVRAAGLAEQYRGQPDLNKEKF" + CDS_motif 22119..22175 + /aSTool="nrps_pks_domains" + /database="abmotifs" + /detection="hmmscan" + /domain_id="nrpspksmotif_PAS_chr1-4_0153_0004" + /evalue="3.80E-11" + /label="NRPS-A_a8" + /locus_tag="PAS_chr1-4_0153" + /protein_end="725" + /protein_start="706" + /score="35.0" + /tool="antismash" + /translation="GRADDQVKIRGFRIELGEI" + aSDomain 22578..22784 + /aSDomain="PCP" + /aSTool="nrps_pks_domains" + /database="nrpspksdomains.hmm" + /detection="hmmscan" + /domain_id="nrpspksdomains_PAS_chr1-4_0153_PCP.1" + /evalue="1.40E-17" + /label="PAS_chr1-4_0153_PCP.1" + /locus_tag="PAS_chr1-4_0153" + /protein_end="928" + /protein_start="859" + /score="55.6" + /tool="antismash" + /translation="LQIKDLWLQVLPNPPASISLEDSFFDLGGHSILATRMIFELRRKL + AVDLPLGTIFKHPTVKLFAAEVDR" + PFAM_domain 22581..22772 + /aSDomain="PP-binding" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00550.28" + /description="Phosphopantetheine attachment site" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0153_0021" + /evalue="2.30E-13" + /label="PAS_chr1-4_0153" + /locus_tag="PAS_chr1-4_0153" + /protein_end="924" + /protein_start="860" + /score="50.4" + /tool="antismash" + /translation="QIKDLWLQVLPNPPASISLEDSFFDLGGHSILATRMIFELRRKLA + VDLPLGTIFKHPTVKLFAA" + aSDomain 22953..24095 + /aSDomain="TIGR01746" + /aSTool="tigrfam" + /description="Thioester-redct: thioester reductase domain" + /detection="hmmscan" + /domain_id="TIGRFam_PAS_chr1-4_0153_0006" + /evalue="1.20E-111" + /identifier="TIGR01746" + /label="PAS_chr1-4_0153" + /locus_tag="PAS_chr1-4_0153" + /protein_end="1365" + /protein_start="984" + /score="371.5" + /tool="antismash" + /translation="NIFLTGATGFLGSYILKDLLERDLDVQVYAHVRAKDEESGLERLR + NTGKVYGIWNEEWTSRIKVVIADLSKDKLGLSGEKYAELANTIDLIIHNGALVHWVYPY + SKLRDANVISTINVLNLAASGKPKQFGFVSSTSTLDTEHYITLSDTLTEQGEDGIPESD + DLLGSSKGLGTGYGQSKWAAEYIIRRAFERGLRGAIIRPGYVTGHSRTGACNTDDFLLR + MLKGCAELGKLPNISNTVNMVPVDHVALVVTASSLHPTAEEGHCVVQVTGHPRIRFNEF + LNALNDYGYEVKLTDYVEWKRDLERFVVDQSKDSALYPLLHFVLDNLPQDTKAPELDDK + NAKDILSGDTRWTGYDGSKGRGVDSAQTGIYIAYLIKTGFL" + aSDomain 22962..23702 + /aSDomain="NAD_binding_4" + /aSTool="nrps_pks_domains" + /database="nrpspksdomains.hmm" + /detection="hmmscan" + /domain_id="nrpspksdomains_PAS_chr1-4_0153_NAD_binding_4.1" + /evalue="4.70E-77" + /label="PAS_chr1-4_0153_NAD_binding_4.1" + /locus_tag="PAS_chr1-4_0153" + /protein_end="1234" + /protein_start="987" + /score="250.3" + /tool="antismash" + /translation="LTGATGFLGSYILKDLLERDLDVQVYAHVRAKDEESGLERLRNTG + KVYGIWNEEWTSRIKVVIADLSKDKLGLSGEKYAELANTIDLIIHNGALVHWVYPYSKL + RDANVISTINVLNLAASGKPKQFGFVSSTSTLDTEHYITLSDTLTEQGEDGIPESDDLL + GSSKGLGTGYGQSKWAAEYIIRRAFERGLRGAIIRPGYVTGHSRTGACNTDDFLLRMLK + GCAELGKLPNISNTVNMVPVDHVAL" + PFAM_domain 22962..23702 + /aSDomain="NAD_binding_4" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF07993.15" + /description="Male sterility protein" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0153_0022" + /evalue="4.60E-77" + /label="PAS_chr1-4_0153" + /locus_tag="PAS_chr1-4_0153" + /protein_end="1234" + /protein_start="987" + /score="258.8" + /tool="antismash" + /translation="LTGATGFLGSYILKDLLERDLDVQVYAHVRAKDEESGLERLRNTG + KVYGIWNEEWTSRIKVVIADLSKDKLGLSGEKYAELANTIDLIIHNGALVHWVYPYSKL + RDANVISTINVLNLAASGKPKQFGFVSSTSTLDTEHYITLSDTLTEQGEDGIPESDDLL + GSSKGLGTGYGQSKWAAEYIIRRAFERGLRGAIIRPGYVTGHSRTGACNTDDFLLRMLK + GCAELGKLPNISNTVNMVPVDHVAL" + gene complement(<24228..>26678) + /db_xref="GeneID:8197138" + /locus_tag="PAS_chr1-4_0154" + mRNA complement(<24228..>26678) + /db_xref="GeneID:8197138" + /locus_tag="PAS_chr1-4_0154" + /product="Protein that recognizes and binds damaged DNA in + an ATP-dependent manner (with Rad7p)" + /transcript_id="XM_002490220.1" + CDS complement(24228..26678) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0154" + /db_xref="EnsemblGenomes-Tr:CAY67984" + /db_xref="GeneID:8197138" + /db_xref="GOA:C4QXL1" + /db_xref="InterPro:IPR000330" + /db_xref="InterPro:IPR001650" + /db_xref="InterPro:IPR001841" + /db_xref="InterPro:IPR013083" + /db_xref="InterPro:IPR014001" + /db_xref="InterPro:IPR017907" + /db_xref="InterPro:IPR018957" + /db_xref="InterPro:IPR027417" + /db_xref="UniProtKB/TrEMBL:C4QXL1" + /locus_tag="PAS_chr1-4_0154" + /product="Protein that recognizes and binds damaged DNA in + an ATP-dependent manner (with Rad7p)" + /protein_id="XP_002490265.1" + /transl_table=1 + /translation="MTKASEAGGFIVDDPDYKKPARRRRAAKKAVSYVETDDELPPNGT + SSSKSSRKRKVKDESEDEEYQESLGTDKVDDIKPEDDEEEDAIVIRGTSTGRNRPNGAS + IVNAISLSDLSDLSDLEQNIDIPEELEELDLEVVEEAEAPRPKKKRKTPAKPKKPRVPY + FTRVTEKLYNIHPSLKDVFPNLDQHEQIEVKKATQPEGMTCTLLPFQLEGLNWLVKQEE + SEFGGGVLADEMGMGKTIQTIALFMHDRTKSPNLVIAPTVALMQWKSEIELHTNGILKV + GVFHGQNRGKSAEELKEYDVILTTYSVLESVYRKQNYGFKRKRGLVKEPSPLHNTHFYR + VILDEAHNIKDRQSGTAKAANSLDTEKRWCLSGTPLQNRIGEMYSLIRFMKLYPFCEYF + CTKCDCRSTEWKFTNWKCCDTCGHTPMLHTNFFNHFMLKNIQKYGVEGLGLESFKNIRL + LLKNIMLRRTKVQRADDLGLPPRIVEIRRDRFNEEEKDLYASLYSDSKRKFNDYVAEGV + VLNNYANIFTLITRMRQLADHPDLVLRRVGTNSIDSSGMPEGVIVCQLCDDEAEEPIES + KCHHKFCRLCVSEYVEGFNGDPNKLECPVCHLALSIDLEGPAIEVDLELIKKGSIVNRI + RMGGEWRSSTKIEALVEELFHLRSDRVTIKSIVFSQFTSMLDLVEWRLKRAGFETVKLQ + GSMSPLQRESTIKHFMETPSVEVFLVSLKAGGVALNLCEASQVFILDPWWNPSVEWQSG + DRVHRIGQHRPVKITRFCIEDSIESRIIELQDKKANMIHATINQDDAAISRLTPSDLQF + LFMN" + PFAM_domain complement(24399..24743) + /aSDomain="Helicase_C" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00271.34" + /description="Helicase conserved C-terminal domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0154_0025" + /evalue="5.70E-13" + /label="PAS_chr1-4_0154" + /locus_tag="PAS_chr1-4_0154" + /protein_end="760" + /protein_start="645" + /score="49.3" + /tool="antismash" + /translation="KIEALVEELFHLRSDRVTIKSIVFSQFTSMLDLVEWRLKRAGFET + VKLQGSMSPLQRESTIKHFMETPSVEVFLVSLKAGGVALNLCEASQVFILDPWWNPSVE + WQSGDRVHRIG" + PFAM_domain complement(24861..24992) + /aSDomain="zf-C3HC4" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00097.28" + /db_xref="GO:0046872" + /description="Zinc finger, C3HC4 type (RING finger)" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0154_0024" + /evalue="3.90E-07" + /gene_ontologies="GO:0046872: metal ion binding" + /label="PAS_chr1-4_0154" + /locus_tag="PAS_chr1-4_0154" + /protein_end="606" + /protein_start="562" + /score="29.9" + /tool="antismash" + /translation="CQLCDDEAEEPIESKCHHKFCRLCVSEYVEGFNGDPNKLECPVC" + PFAM_domain complement(25053..26024) + /aSDomain="SNF2-rel_dom" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00176.26" + /db_xref="GO:0005524" + /db_xref="GO:0140658" + /description="SNF2-related domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0154_0023" + /evalue="1.10E-54" + /gene_ontologies="GO:0005524: ATP binding" + /gene_ontologies="GO:0140658: ATP-dependent chromatin + remodeler activity" + /label="PAS_chr1-4_0154" + /locus_tag="PAS_chr1-4_0154" + /protein_end="542" + /protein_start="218" + /score="185.6" + /tool="antismash" + /translation="KQEESEFGGGVLADEMGMGKTIQTIALFMHDRTKSPNLVIAPTVA + LMQWKSEIELHTNGILKVGVFHGQNRGKSAEELKEYDVILTTYSVLESVYRKQNYGFKR + KRGLVKEPSPLHNTHFYRVILDEAHNIKDRQSGTAKAANSLDTEKRWCLSGTPLQNRIG + EMYSLIRFMKLYPFCEYFCTKCDCRSTEWKFTNWKCCDTCGHTPMLHTNFFNHFMLKNI + QKYGVEGLGLESFKNIRLLLKNIMLRRTKVQRADDLGLPPRIVEIRRDRFNEEEKDLYA + SLYSDSKRKFNDYVAEGVVLNNYANIFTLITRMRQLADHPDLV" + gene complement(<27038..>30091) + /db_xref="GeneID:8197139" + /locus_tag="PAS_chr1-4_0155" + mRNA complement(<27038..>30091) + /db_xref="GeneID:8197139" + /locus_tag="PAS_chr1-4_0155" + /product="Hypothetical protein" + /transcript_id="XM_002490221.1" + CDS complement(27038..30091) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0155" + /db_xref="EnsemblGenomes-Tr:CAY67985" + /db_xref="GeneID:8197139" + /db_xref="GOA:C4QXL2" + /db_xref="InterPro:IPR003101" + /db_xref="InterPro:IPR008626" + /db_xref="UniProtKB/TrEMBL:C4QXL2" + /locus_tag="PAS_chr1-4_0155" + /product="Hypothetical protein" + /protein_id="XP_002490266.1" + /transl_table=1 + /translation="MNGLPQQPWHSELNPKERQGFINIIVQSVFQIQGNNSFNNAKTKQ + LAEDFEKWAFSNARSKKEYVDMLRNKVSSIKQAAVNGRSSMAANAPDPAATLNGMQSMG + QQNIPVQPQMQQHQQQNQYMKNNQQQQPQQQQQQQQPQRPMMNNFSNDQRVNLKTAPIP + EALLKRIPGLPVGVNTWAQITQMLQNGQINPQLMNTIKQVYTVHSQLLQARSHQDAMQK + PPQQPQVQTQPQTQPQPQRDQMFMQQNRMANNQQHIQQQAQNPQFNSKLVQGQQQQQPQ + QPPQQSATQQPQLQITQEMLREGTTQALNLIERLKQTGDLPQTLAPAQQQSFIKTFIQR + HYLPRVLQNKNATANPSSQQANNQNSVPQAVPGFPGQSVPLQQAQKFVNTSPLMNQTLP + TTFNNARPMQKPQQQKQPQQSVPSNSMFGALPNAQQPVPNMHQQQQKQPIKLLPGIQAT + EEDWTNLRKVYAEALQLPIKLKNVTNEITPDQKRAVLDQAKTMIQLSITTENLIPNFFI + ATKNVEGTRRLIQIKFMLKEVLESLKRNEYLATPNILQRVQTQIHKYITYLKELQQRKF + QQLQNVQSLQQQQQQQQQTSNLQQVPQMGQGNKQLPNNMLYTSQTNPDSLMGGSNANNM + FSGLGIQDPSLNNTAAFSQQQRVTPASGQQLNSSPLMQTPMLNQNSLMPNQIQQFPPQQ + QQHRQQQRALPQQRLAQQVQTSPNAKPQQYMQQLPNNMPQPQHSQQPYQASLEQQVPQQ + MLQQPQQRQQLQQQVPIQQVQQAKRKVKSSVSGPSTGAPGKQAKVQGNRMAATNAAAKS + SPVVMATPSSVQSPENLVATKEQNEIQAKEEAESAAINTSRMRIKELGLDDPASYFLCM + LSRSLDLKDEETQLLDSKESNSVKKDTISQKGITPSAILQTPLSFIKTPGSSRPLDSPS + TSKNANEWSSKVTPAAINAVFRDVSAISKTLSFGMLPTPPEENEVLKRSSDADEEPSKK + AKLENKLQNSLWDFDYAEELFATDHLSP" + PFAM_domain complement(28382..28717) + /aSDomain="Med15_fungi" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF05397.15" + /db_xref="GO:0003712" + /db_xref="GO:0006357" + /db_xref="GO:0016592" + /description="Mediator complex subunit 15" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0155_0028" + /evalue="1.30E-30" + /gene_ontologies="GO:0003712: transcription coregulator + activity" + /gene_ontologies="GO:0006357: regulation of transcription + by RNA polymerase II" + /gene_ontologies="GO:0016592: mediator complex" + /label="PAS_chr1-4_0155" + /locus_tag="PAS_chr1-4_0155" + /protein_end="570" + /protein_start="458" + /score="106.0" + /tool="antismash" + /translation="EEDWTNLRKVYAEALQLPIKLKNVTNEITPDQKRAVLDQAKTMIQ + LSITTENLIPNFFIATKNVEGTRRLIQIKFMLKEVLESLKRNEYLATPNILQRVQTQIH + KYITYLKE" + PFAM_domain complement(29441..29641) + /aSDomain="Gal11_ABD1" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF18535.4" + /description="Gal11 activator-binding domain (ABD1)" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0155_0027" + /evalue="6.40E-14" + /label="PAS_chr1-4_0155" + /locus_tag="PAS_chr1-4_0155" + /protein_end="217" + /protein_start="150" + /score="51.9" + /tool="antismash" + /translation="NDQRVNLKTAPIPEALLKRIPGLPVGVNTWAQITQMLQNGQINPQ + LMNTIKQVYTVHSQLLQARSHQ" + PFAM_domain complement(29837..30073) + /aSDomain="KIX_2" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF16987.8" + /description="KIX domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0155_0026" + /evalue="2.00E-16" + /label="PAS_chr1-4_0155" + /locus_tag="PAS_chr1-4_0155" + /protein_end="85" + /protein_start="6" + /score="59.9" + /tool="antismash" + /translation="QPWHSELNPKERQGFINIIVQSVFQIQGNNSFNNAKTKQLAEDFE + KWAFSNARSKKEYVDMLRNKVSSIKQAAVNGRSS" + gene <31016..>31489 + /db_xref="GeneID:8197140" + /locus_tag="PAS_chr1-4_0156" + mRNA <31016..>31489 + /db_xref="GeneID:8197140" + /locus_tag="PAS_chr1-4_0156" + /product="Hypothetical protein" + /transcript_id="XM_002490222.1" + CDS 31016..31489 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0156" + /db_xref="EnsemblGenomes-Tr:CAY67986" + /db_xref="GeneID:8197140" + /db_xref="InterPro:IPR025355" + /db_xref="UniProtKB/TrEMBL:C4QXL3" + /locus_tag="PAS_chr1-4_0156" + /product="Hypothetical protein" + /protein_id="XP_002490267.1" + /transl_table=1 + /translation="MGAWVMDVFHDHTSLDFLDNLLKSQDQVKFVVDSLAAPVPQTLED + GEIDCSESFQKLMSAIFLAIWLDFDTKIPLAKAKYSGHITDGIEETYDKVKDSPDFQEL + EKQGQFFKNQAKQWLKSLSENPELSELCELWIKDPENYKKWKENIDWVIDFVS" + PFAM_domain 31019..31456 + /aSDomain="DUF4259" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF14078.9" + /description="Domain of unknown function (DUF4259)" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0156_0029" + /evalue="2.70E-29" + /label="PAS_chr1-4_0156" + /locus_tag="PAS_chr1-4_0156" + /protein_end="147" + /protein_start="1" + /score="102.8" + /tool="antismash" + /translation="GAWVMDVFHDHTSLDFLDNLLKSQDQVKFVVDSLAAPVPQTLEDG + EIDCSESFQKLMSAIFLAIWLDFDTKIPLAKAKYSGHITDGIEETYDKVKDSPDFQELE + KQGQFFKNQAKQWLKSLSENPELSELCELWIKDPENYKKWKE" + gene complement(<31583..>32020) + /db_xref="GeneID:8197141" + /locus_tag="PAS_chr1-4_0157" + mRNA complement(<31583..>32020) + /db_xref="GeneID:8197141" + /locus_tag="PAS_chr1-4_0157" + /product="Hypothetical protein" + /transcript_id="XM_002490223.1" + CDS complement(31583..32020) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0157" + /db_xref="EnsemblGenomes-Tr:CAY67987" + /db_xref="GeneID:8197141" + /db_xref="UniProtKB/TrEMBL:C4QXL4" + /locus_tag="PAS_chr1-4_0157" + /product="Hypothetical protein" + /protein_id="XP_002490268.1" + /transl_table=1 + /translation="MDQENSQLRNFHGLLVLARLLDDYISKTLQQDAVKDDTMVQNDLK + WTQTEIKETISRVSPLASTLTSNNSSSNAEKKEIFVQVCAYFGGVLDNVIVIFKETTEL + SMLPTLETLQNNLCAIESGGDAGGDLSLLIKEAIEQLQRQR" + gene complement(<32204..>32857) + /db_xref="GeneID:8197142" + /locus_tag="PAS_chr1-4_0158" + mRNA complement(<32204..>32857) + /db_xref="GeneID:8197142" + /locus_tag="PAS_chr1-4_0158" + /product="Clathrin light chain" + /transcript_id="XM_002490224.1" + CDS complement(32204..32857) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0158" + /db_xref="EnsemblGenomes-Tr:CAY67988" + /db_xref="GeneID:8197142" + /db_xref="GOA:C4QXL5" + /db_xref="InterPro:IPR000996" + /db_xref="UniProtKB/TrEMBL:C4QXL5" + /locus_tag="PAS_chr1-4_0158" + /product="Clathrin light chain" + /protein_id="XP_002490269.1" + /transl_table=1 + /translation="MADKFPELKDVDTGASSGESPSQGDFLSREKELLGDEFTTERDQE + LADDNVDEFDEFESNFPKVDADQEESIPVEDAPEEEAHTPLHSTFDNLDLKESKPIQEW + KERTELEISKRDEVAAKKHEEIKKQAEKDVDDFYVNYNDKKEKSLKATKEDEEKFIAKR + DSFFDQGSVWDRTVELLKLKKNSSFGADEADKTRFKEILLSLKGKENVPGAAGY" + PFAM_domain complement(32216..32845) + /aSDomain="Clathrin_lg_ch" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF01086.20" + /db_xref="GO:0005198" + /db_xref="GO:0006886" + /db_xref="GO:0016192" + /db_xref="GO:0030130" + /db_xref="GO:0030132" + /description="Clathrin light chain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0158_0030" + /evalue="1.10E-56" + /gene_ontologies="GO:0005198: structural molecule activity" + /gene_ontologies="GO:0006886: intracellular protein + transport" + /gene_ontologies="GO:0016192: vesicle-mediated transport" + /gene_ontologies="GO:0030130: clathrin coat of trans-Golgi + network vesicle" + /gene_ontologies="GO:0030132: clathrin coat of coated pit" + /label="PAS_chr1-4_0158" + /locus_tag="PAS_chr1-4_0158" + /protein_end="214" + /protein_start="4" + /score="192.6" + /tool="antismash" + /translation="FPELKDVDTGASSGESPSQGDFLSREKELLGDEFTTERDQELADD + NVDEFDEFESNFPKVDADQEESIPVEDAPEEEAHTPLHSTFDNLDLKESKPIQEWKERT + ELEISKRDEVAAKKHEEIKKQAEKDVDDFYVNYNDKKEKSLKATKEDEEKFIAKRDSFF + DQGSVWDRTVELLKLKKNSSFGADEADKTRFKEILLSLKGKENVPGA" + gene <33062..>34189 + /db_xref="GeneID:8197143" + /locus_tag="PAS_chr1-4_0159" + mRNA <33062..>34189 + /db_xref="GeneID:8197143" + /locus_tag="PAS_chr1-4_0159" + /product="Protein that interacts with exonuclease Rat1p and + Rai1p" + /transcript_id="XM_002490225.1" + CDS 33062..34189 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0159" + /db_xref="EnsemblGenomes-Tr:CAY67989" + /db_xref="GeneID:8197143" + /db_xref="GOA:C4QXL6" + /db_xref="InterPro:IPR006569" + /db_xref="InterPro:IPR006903" + /db_xref="InterPro:IPR008942" + /db_xref="UniProtKB/TrEMBL:C4QXL6" + /locus_tag="PAS_chr1-4_0159" + /product="Protein that interacts with exonuclease Rat1p and + Rai1p" + /protein_id="XP_002490270.1" + /transl_table=1 + /translation="MSYSKDIVLEKLASLEETQISIQSIGQWCLFHHRHAPETVAIWSE + FVGSTQTKKLAGLYLANEIIQQSRAKRKTTFLDEFAKVLPSTLEQIYPSMISTHQAKLK + RIIDVWSQRKIFDSNLIHRLYQSIQDQKAYNGLSSSSSNSPPINSGDLAPEISSLSTLF + NKISTLKSSTSLVVNQINEQYSSLFDSETLPGTDIYLKQLGDLSTLITSARSKSQETQE + LRESIINELKKLIQVQESWITKDAESSGSLDEKLATVQQKESELKEFINDVEEEDGVPQ + YAASSDEEGDENVSKKRKMESPPTETVDSGEQPTNPVHPQLSSILESLSRTTGLTPEPA + STSDESATATQKQDETPVSSSINPALASLLSKLNG" + PFAM_domain 33083..33433 + /aSDomain="CID" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF04818.16" + /description="CID domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0159_0031" + /evalue="2.80E-32" + /label="PAS_chr1-4_0159" + /locus_tag="PAS_chr1-4_0159" + /protein_end="124" + /protein_start="7" + /score="111.7" + /tool="antismash" + /translation="VLEKLASLEETQISIQSIGQWCLFHHRHAPETVAIWSEFVGSTQT + KKLAGLYLANEIIQQSRAKRKTTFLDEFAKVLPSTLEQIYPSMISTHQAKLKRIIDVWS + QRKIFDSNLIHRL" + gene <34385..>36916 + /db_xref="GeneID:8197144" + /locus_tag="PAS_chr1-4_0160" + mRNA <34385..>36916 + /db_xref="GeneID:8197144" + /locus_tag="PAS_chr1-4_0160" + /product="Multifunctional enzyme HIS4" + /transcript_id="XM_002490226.1" + CDS 34385..36916 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0160" + /db_xref="EnsemblGenomes-Tr:CAY67990" + /db_xref="GeneID:8197144" + /db_xref="GOA:C4QXL7" + /db_xref="InterPro:IPR001692" + /db_xref="InterPro:IPR002496" + /db_xref="InterPro:IPR008179" + /db_xref="InterPro:IPR012131" + /db_xref="InterPro:IPR016161" + /db_xref="InterPro:IPR016298" + /db_xref="InterPro:IPR021130" + /db_xref="UniProtKB/TrEMBL:C4QXL7" + /locus_tag="PAS_chr1-4_0160" + /product="Multifunctional enzyme HIS4" + /protein_id="XP_002490271.1" + /transl_table=1 + /translation="MTFPLLPAYASVAEFDNSLSLVGKAVFPYAADQLHNLIKFTQSTE + LQVNVQVESSVTEDQFEELIDNLLKLYNNGINEVILDLDLAERVVQRIPGARVIYRTLV + DKVASLPANASIAVPFSSPLGDLKSFTNGGSRTVYAFSETAKLVDVTSTVASGIIPIID + ARQLTTEYELSEDVKKFPVSEILLASLTTDRPDGLFTTLVADSSNYSLGLVYSSKKSIP + EAIRTQTGVYQSRRHGLWYKGATSGATQKLLGIELDCDGDCLKFVVEQTGVGFCHLERT + SCFGQSKGLRAMEATLWDRKSNAPEGSYTKRLFDDEVLLNAKIREEADELAEAKSKEDI + AWECADLFYFALVRCAKYGVTLDEVERNLDMKSLKVTRRKGDAKPGYTKEQPKEESKPK + EVPSEGRIELCKIDVSKASSQEIEDALRRPIQKTEQIMELVKPIVDNVRQNGDKALLEL + TAKFDGVALKTPVLEAPFPEELMQLPDNVKRAIDLSIDNVRKFHEAQLTETLQVETCPG + VVCSRFARPIEKVGLYIPGGTAILPSTSLMLGVPAKVAGRKEIVFASPPKKDGTLTPEV + IYVAHKVGAKCIVLAGGAQAVAAMAYGTETVPKCDKIFGPGNQFVTAAKMMVQNDTSAL + CSIDMPAGPSEVLVIADKYADPDFVASDLLSQAEHGIDSQVILLAVDMTDKELARIEDA + VHNQAVQLPRVEIVRKCIAHSTTLSVATYEQALEMSNQYAPEHLILQIENASSYVDQVQ + HAGSVFVGAYSPESCGDYSSGTNHTLPTYGYARQYSGVNTATFQKFITSQDVTPEGLKH + IGQAVMDLAAVEGLDAHRNAVKVRMEKLGLI" + PFAM_domain 35021..35236 + /aSDomain="PRA-CH" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF01502.21" + /db_xref="GO:0000105" + /db_xref="GO:0004635" + /description="Phosphoribosyl-AMP cyclohydrolase" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0160_0032" + /evalue="1.00E-22" + /gene_ontologies="GO:0000105: histidine biosynthetic + process" + /gene_ontologies="GO:0004635: phosphoribosyl-AMP + cyclohydrolase activity" + /label="PAS_chr1-4_0160" + /locus_tag="PAS_chr1-4_0160" + /protein_end="284" + /protein_start="212" + /score="79.9" + /tool="antismash" + /translation="LVYSSKKSIPEAIRTQTGVYQSRRHGLWYKGATSGATQKLLGIEL + DCDGDCLKFVVEQTGVGFCHLERTSCF" + aSDomain 35252..35491 + /aSDomain="TIGR03188" + /aSTool="tigrfam" + /description="histidine_hisI: phosphoribosyl-ATP + diphosphatase" + /detection="hmmscan" + /domain_id="TIGRFam_PAS_chr1-4_0160_0008" + /evalue="5.80E-20" + /identifier="TIGR03188" + /label="PAS_chr1-4_0160" + /locus_tag="PAS_chr1-4_0160" + /protein_end="369" + /protein_start="289" + /score="69.3" + /tool="antismash" + /translation="LRAMEATLWDRKSNAPEGSYTKRLFDDEVLLNAKIREEADELAEA + KSKEDIAWECADLFYFALVRCAKYGVTLDEVERNL" + PFAM_domain 35252..35497 + /aSDomain="PRA-PH" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF01503.20" + /description="Phosphoribosyl-ATP pyrophosphohydrolase" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0160_0033" + /evalue="1.10E-16" + /label="PAS_chr1-4_0160" + /locus_tag="PAS_chr1-4_0160" + /protein_end="371" + /protein_start="289" + /score="61.2" + /tool="antismash" + /translation="LRAMEATLWDRKSNAPEGSYTKRLFDDEVLLNAKIREEADELAEA + KSKEDIAWECADLFYFALVRCAKYGVTLDEVERNLDM" + PFAM_domain 35663..36895 + /aSDomain="Histidinol_dh" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00815.23" + /db_xref="GO:0016616" + /db_xref="GO:0046872" + /db_xref="GO:0051287" + /description="Histidinol dehydrogenase" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0160_0034" + /evalue="2.30E-160" + /gene_ontologies="GO:0016616: oxidoreductase activity, + acting on the CH-OH group of donors, NAD or NADP as + acceptor" + /gene_ontologies="GO:0046872: metal ion binding" + /gene_ontologies="GO:0051287: NAD binding" + /label="PAS_chr1-4_0160" + /locus_tag="PAS_chr1-4_0160" + /protein_end="837" + /protein_start="426" + /score="534.2" + /tool="antismash" + /translation="RRPIQKTEQIMELVKPIVDNVRQNGDKALLELTAKFDGVALKTPV + LEAPFPEELMQLPDNVKRAIDLSIDNVRKFHEAQLTETLQVETCPGVVCSRFARPIEKV + GLYIPGGTAILPSTSLMLGVPAKVAGRKEIVFASPPKKDGTLTPEVIYVAHKVGAKCIV + LAGGAQAVAAMAYGTETVPKCDKIFGPGNQFVTAAKMMVQNDTSALCSIDMPAGPSEVL + VIADKYADPDFVASDLLSQAEHGIDSQVILLAVDMTDKELARIEDAVHNQAVQLPRVEI + VRKCIAHSTTLSVATYEQALEMSNQYAPEHLILQIENASSYVDQVQHAGSVFVGAYSPE + SCGDYSSGTNHTLPTYGYARQYSGVNTATFQKFITSQDVTPEGLKHIGQAVMDLAAVEG + LDAHRNAVKVRM" + aSDomain 35702..36892 + /aSDomain="TIGR00069" + /aSTool="tigrfam" + /description="hisD: histidinol dehydrogenase" + /detection="hmmscan" + /domain_id="TIGRFam_PAS_chr1-4_0160_0007" + /evalue="2.00E-149" + /identifier="TIGR00069" + /label="PAS_chr1-4_0160" + /locus_tag="PAS_chr1-4_0160" + /protein_end="836" + /protein_start="439" + /score="496.1" + /tool="antismash" + /translation="VKPIVDNVRQNGDKALLELTAKFDGVALKTPVLEAPFPEELMQLP + DNVKRAIDLSIDNVRKFHEAQLTETLQVETCPGVVCSRFARPIEKVGLYIPGGTAILPS + TSLMLGVPAKVAGRKEIVFASPPKKDGTLTPEVIYVAHKVGAKCIVLAGGAQAVAAMAY + GTETVPKCDKIFGPGNQFVTAAKMMVQNDTSALCSIDMPAGPSEVLVIADKYADPDFVA + SDLLSQAEHGIDSQVILLAVDMTDKELARIEDAVHNQAVQLPRVEIVRKCIAHSTTLSV + ATYEQALEMSNQYAPEHLILQIENASSYVDQVQHAGSVFVGAYSPESCGDYSSGTNHTL + PTYGYARQYSGVNTATFQKFITSQDVTPEGLKHIGQAVMDLAAVEGLDAHRNAVKVR" + gene <37042..>38217 + /db_xref="GeneID:8197145" + /locus_tag="PAS_chr1-4_0161" + mRNA <37042..>38217 + /db_xref="GeneID:8197145" + /locus_tag="PAS_chr1-4_0161" + /product="Nuclear fusion protein BIK1" + /transcript_id="XM_002490227.1" + CDS 37042..38217 + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0161" + /db_xref="EnsemblGenomes-Tr:CAY67991" + /db_xref="GeneID:8197145" + /db_xref="InterPro:IPR000938" + /db_xref="UniProtKB/TrEMBL:C4QXL8" + /locus_tag="PAS_chr1-4_0161" + /product="Nuclear fusion protein BIK1" + /protein_id="XP_002490272.1" + /transl_table=1 + /translation="MELHVPLGSEIVLPGGERAILKFVGNVESKSGIFAGVELIGQMSG + KGKNSGEFKNVQYFTTKVPNSGIFLPYQRLLETSNMQRLQAETPTKTKRNVYVSRSPLA + VSNQQGLKRSSKESSPSTVAGNEGQLHSLKTENTHLSQKCLKLETQLQECTEVLESMEK + VIKDHYEPAFNQMEKDLSEKNEKISKLKVSFDEQKTELLDIIDSLEKQASETEQLYTKE + LKRLREECAAYKNKDTAKETNELQRQLKVKEKMCQDWELKYTQLKDSKSKEENDIIQGY + QREIDDLKAKLSSSQKAQPEKNTEIEEQLQRLKAENRSLQQQLETAREKEKIQPLTSTT + TEQSTLLDENGNLQIFVPKNSDPANGRKKWCGLCEREGHDSVQCPFENDMF" + PFAM_domain 37063..37263 + /aSDomain="CAP_GLY" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF01302.28" + /description="CAP-Gly domain" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0161_0035" + /evalue="1.50E-13" + /label="PAS_chr1-4_0161" + /locus_tag="PAS_chr1-4_0161" + /protein_end="74" + /protein_start="7" + /score="50.6" + /tool="antismash" + /translation="GSEIVLPGGERAILKFVGNVESKSGIFAGVELIGQMSGKGKNSGE + FKNVQYFTTKVPNSGIFLPYQR" + gene complement(<38302..>38988) + /db_xref="GeneID:8197146" + /locus_tag="PAS_chr1-4_0162" + mRNA complement(join(<38302..38864,38931..>38988)) + /db_xref="GeneID:8197146" + /locus_tag="PAS_chr1-4_0162" + /product="GTPase, similar to Ypt51p and Ypt53p and to + mammalian rab5" + /transcript_id="XM_002490228.1" + CDS complement(join(38302..38864,38931..38988)) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0162" + /db_xref="EnsemblGenomes-Tr:CAY67992" + /db_xref="GeneID:8197146" + /db_xref="GOA:C4QXL9" + /db_xref="InterPro:IPR001806" + /db_xref="InterPro:IPR003579" + /db_xref="InterPro:IPR005225" + /db_xref="InterPro:IPR027417" + /db_xref="UniProtKB/TrEMBL:C4QXL9" + /locus_tag="PAS_chr1-4_0162" + /product="GTPase, similar to Ypt51p and Ypt53p and to + mammalian rab5" + /protein_id="XP_002490273.1" + /transl_table=1 + /translation="MADLVTQEPRFAQFKLVLLGESAVGKSSIVHRFVTDSFDDLREST + IGAAFLTQTIQLDERTTIKFEIWDTAGQERYKSLAPMYYRNANCALVAYDITQESSLDR + AKSWIQELQKQASADIVVALVGNKLDLEAERKVSTKEAKEYADELGLIFKEISAKTGEG + IKDVFHSIASKLPVEEKLNSATKRRRNIDLNRPSTNNQESCSC" + PFAM_domain complement(join(38398..38864,38931..38946)) + /aSDomain="Ras" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00071.25" + /db_xref="GO:0003924" + /db_xref="GO:0005525" + /description="Ras family" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0162_0036" + /evalue="6.00E-59" + /gene_ontologies="GO:0003924: GTPase activity" + /gene_ontologies="GO:0005525: GTP binding" + /label="PAS_chr1-4_0162" + /locus_tag="PAS_chr1-4_0162" + /protein_end="175" + /protein_start="14" + /score="198.4" + /tool="antismash" + /translation="KLVLLGESAVGKSSIVHRFVTDSFDDLRESTIGAAFLTQTIQLDE + RTTIKFEIWDTAGQERYKSLAPMYYRNANCALVAYDITQESSLDRAKSWIQELQKQASA + DIVVALVGNKLDLEAERKVSTKEAKEYADELGLIFKEISAKTGEGIKDVFHSIASKL" + aSDomain complement(join(38413..38864,38931..38952)) + /aSDomain="TIGR00231" + /aSTool="tigrfam" + /description="small_GTP: small GTP-binding protein domain" + /detection="hmmscan" + /domain_id="TIGRFam_PAS_chr1-4_0162_0009" + /evalue="4.90E-28" + /identifier="TIGR00231" + /label="PAS_chr1-4_0162" + /locus_tag="PAS_chr1-4_0162" + /protein_end="170" + /protein_start="12" + /score="95.9" + /tool="antismash" + /translation="QFKLVLLGESAVGKSSIVHRFVTDSFDDLRESTIGAAFLTQTIQL + DERTTIKFEIWDTAGQERYKSLAPMYYRNANCALVAYDITQESSLDRAKSWIQELQKQA + SADIVVALVGNKLDLEAERKVSTKEAKEYADELGLIFKEISAKTGEGIKDVFHS" + gene complement(<39207..>39580) + /db_xref="GeneID:8197147" + /locus_tag="PAS_chr1-4_0163" + mRNA complement(join(<39207..39518,39578..>39580)) + /db_xref="GeneID:8197147" + /locus_tag="PAS_chr1-4_0163" + /product="uncharacterized protein" + /transcript_id="XM_002490229.1" + CDS complement(join(39207..39518,39578..39580)) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0163" + /db_xref="EnsemblGenomes-Tr:CAY67993" + /db_xref="GeneID:8197147" + /db_xref="GOA:C4QXM0" + /db_xref="InterPro:IPR011032" + /db_xref="InterPro:IPR018369" + /db_xref="InterPro:IPR020818" + /db_xref="UniProtKB/TrEMBL:C4QXM0" + /locus_tag="PAS_chr1-4_0163" + /product="uncharacterized protein" + /protein_id="XP_002490274.1" + /transl_table=1 + /translation="MSTLLKSANSLKPLLNRVLVQRAKAATKTASGIYIPEKNVEKLHQ + ATVIATGPGVPNQNGSLEPTIVKAGDNVLIPSFGGSPVKINDEEYLLFSDREILAKIEN + " + PFAM_domain complement(39216..39491) + /aSDomain="Cpn10" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00166.24" + /db_xref="GO:0005524" + /db_xref="GO:0006457" + /db_xref="GO:0044183" + /description="Chaperonin 10 Kd subunit" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0163_0037" + /evalue="3.50E-27" + /gene_ontologies="GO:0005524: ATP binding" + /gene_ontologies="GO:0006457: protein folding" + /gene_ontologies="GO:0044183: protein folding chaperone" + /label="PAS_chr1-4_0163" + /locus_tag="PAS_chr1-4_0163" + /protein_end="102" + /protein_start="10" + /score="94.4" + /tool="antismash" + /translation="LKPLLNRVLVQRAKAATKTASGIYIPEKNVEKLHQATVIATGPGV + PNQNGSLEPTIVKAGDNVLIPSFGGSPVKINDEEYLLFSDREILAKI" + gene complement(<39772..>41631) + /db_xref="GeneID:8197148" + /locus_tag="PAS_chr1-4_0695" + mRNA complement(<39772..>41631) + /db_xref="GeneID:8197148" + /locus_tag="PAS_chr1-4_0695" + /product="uncharacterized protein" + /transcript_id="XM_002490230.1" + CDS complement(39772..41631) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0695" + /db_xref="EnsemblGenomes-Tr:CAY67994" + /db_xref="GeneID:8197148" + /db_xref="UniProtKB/TrEMBL:C4QXM1" + /locus_tag="PAS_chr1-4_0695" + /product="uncharacterized protein" + /protein_id="XP_002490275.1" + /transl_table=1 + /translation="MTEQLIEWFRDPSNKAYWNEDLVAIRESPLGGVGVFAKEKIGHDE + EDDEENLLLRVSKQSILSGKNSFISNLLHECGADSHLGLILAFLYEKSLGSDSPWYAYL + QTIQPKNTKGLILPVHLWPDEKKNLLIGTELYSVLDNFEEETEGLFESCVSFAREYESV + LKVPTELAVDENNAKEKLLEFAAITLAIASRSFNVDNYHELALVPGADLFNHDSYGREH + VHFEALGDVCPFCASCDECGHIEHGAPDSEIESDLEQEGDNEEDEEDKVHDDADTEDGM + EDNKKEGNNEPFEVTEDYITKLEKELEREDMSDEESDASEAEGHDNSDSDMSDIDEDSL + LIPDVCCDIKIVKSIPKNKELLNTYGDLNNTSLLTKYGFTSLNNPNDYVSLGDQALSQL + KNFPDRKDWWDSKGYEVFNDYLHYTAQLNQEEYDNEGVEDKEEKEGHKNGEEGDDQYHS + DAECQSCNGDSQASPGSCCNSCDGGNDEGEEEEEEQPEYLPWQVELRVNAEGRPSQSTY + ALARLLSLSEAEFQELREADDKTLFLEKIGTLESPEKAAYQNILNWCKQRSTAYQDGGL + TSNDYEKAIRVTKDSQKLAISILVFGEKKVLEQSIASLTQQIN" + gene complement(<41777..>42664) + /db_xref="GeneID:8197439" + /locus_tag="PAS_chr1-4_0164" + mRNA complement(<41777..>42664) + /db_xref="GeneID:8197439" + /locus_tag="PAS_chr1-4_0164" + /product="uncharacterized protein" + /transcript_id="XM_002490231.1" + CDS complement(41777..42664) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0164" + /db_xref="EnsemblGenomes-Tr:CAY67995" + /db_xref="GeneID:8197439" + /db_xref="GOA:C4QXM2" + /db_xref="InterPro:IPR001283" + /db_xref="InterPro:IPR014044" + /db_xref="InterPro:IPR018244" + /db_xref="UniProtKB/TrEMBL:C4QXM2" + /locus_tag="PAS_chr1-4_0164" + /product="uncharacterized protein" + /protein_id="XP_002490276.1" + /transl_table=1 + /translation="MRLLHISLLSIISVLTKANAECCYTNTHTTTEVWYTTVYARDVSE + ETSSTLAGGSATVSSEVSSTIESSVATSATTESSSETSGSTSGSTSATESSTGSSSLAT + SSSITSSESSTITQTTGQESTSPTPSSSETGSSTTTPYDISPTASSDFDAFKYQILDEH + NIKRALHGVDGLEWDEEVYAAAQAYADAYTCDGTLVHSGNSLYGENLAYGYSTRGTVDA + WYSEIEYYDFNNPGYTPGVGHFTQVVWKSTTKLGCAFKYCNDYYGAYVVCNYSPPGNYV + NEGYFEANVLPLVD" + PFAM_domain complement(41843..42187) + /aSDomain="CAP" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF00188.29" + /description="Cysteine-rich secretory protein family" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0164_0038" + /evalue="2.40E-21" + /label="PAS_chr1-4_0164" + /locus_tag="PAS_chr1-4_0164" + /protein_end="274" + /protein_start="159" + /score="77.0" + /tool="antismash" + /translation="LDEHNIKRALHGVDGLEWDEEVYAAAQAYADAYTCDGTLVHSGNS + LYGENLAYGYSTRGTVDAWYSEIEYYDFNNPGYTPGVGHFTQVVWKSTTKLGCAFKYCN + DYYGAYVVCNY" + gene complement(<43032..>44159) + /db_xref="GeneID:8197149" + /locus_tag="PAS_chr1-4_0165" + mRNA complement(<43032..>44159) + /db_xref="GeneID:8197149" + /locus_tag="PAS_chr1-4_0165" + /product="Class E protein of the vacuolar protein-sorting + (Vps) pathway" + /transcript_id="XM_002490232.1" + CDS complement(43032..44159) + /codon_start=1 + /db_xref="EnsemblGenomes-Gn:PAS_chr1-4_0165" + /db_xref="EnsemblGenomes-Tr:CAY67996" + /db_xref="GeneID:8197149" + /db_xref="InterPro:IPR019194" + /db_xref="UniProtKB/TrEMBL:C4QXM3" + /locus_tag="PAS_chr1-4_0165" + /product="Class E protein of the vacuolar protein-sorting + (Vps) pathway" + /protein_id="XP_002490277.1" + /transl_table=1 + /translation="MSEVLDIPDGEYDLDISSLLCDDSVNLGVRYNFKPDSIDMDYPLE + LVQESSNYILKAESDPNVRKEPLVFEGTLGKTNQHDYLLIYDDITKRFQMDRFNGVLRM + NKSRAPDKLLTKFEKLKLGKDSPASGSRPYVATANHTALRKVTPFKLETKLKPTKPLEN + RVHIHMKESKPKNSSSLTESVDKKKQEVSIPKVHLTPHTPSSILVSKAEHPKVASKRPP + NTPLEFQDDSNDNNDNGDDDDDLTSFVGELEAEMGIETPPPTQERAGLVGIGISKSDKS + TDQQSATQMELSKDSFHEDNWQPNYSDWESDLEEVPASNSINFFVDDDPKSKEFQNQAT + YVNPEFHNTPASSVARPISMKELATTTFSQSSKSS" + PFAM_domain complement(43830..44126) + /aSDomain="EAF" + /aSTool="clusterhmmer" + /database="35.0" + /db_xref="PF09816.12" + /description="RNA polymerase II transcription elongation + factor" + /detection="hmmscan" + /domain_id="clusterhmmer_PAS_chr1-4_0165_0039" + /evalue="3.90E-17" + /label="PAS_chr1-4_0165" + /locus_tag="PAS_chr1-4_0165" + /protein_end="110" + /protein_start="11" + /score="62.6" + /tool="antismash" + /translation="YDLDISSLLCDDSVNLGVRYNFKPDSIDMDYPLELVQESSNYILK + AESDPNVRKEPLVFEGTLGKTNQHDYLLIYDDITKRFQMDRFNGVLRMNKSRAP" +ORIGIN + 1 tttggtcata cgatcgacac caatcattcc agatatgaaa attgccttct tcaagtgcac + 61 tgtctgcgat catacgatgg aggtcgaaaa tgatagaggt gtcattcaag agcccacaaa + 121 atgtccccga gaagtttgtg cgcaagcaaa ctcaatgcaa ttgatccaca accgatcaac + 181 atttgccgat aagcaagtta ttaagttgca agaaacacct gatttggtac cagatggaca + 241 aactcctcac tccgtgtctc tatgcgtata cgatgagctg gttgatactg tgagagctgg + 301 tgatagagta gaagtgtgtg gtatattccg ttccgttcca gtacgtacca acgctatcca + 361 aagaacagtg aaggctcttt tcaaaacata tttggatgtt gttcatataa agaaggttga + 421 cagaaaacgg atggcagctg atatatcgac tttggagaat gaagtctctg agcaacagga + 481 agtggaagaa gtgaagaagc tttcggagga agatatcgaa atgattcatc aaatctctga + 541 acgacctgac ttatacgaag ttctgtctcg ctctttggct ccatctatct acgaaatgga + 601 tgatgtcaag aagggaattc ttcttcaact ctttggagga acaaataaag agttcgaaaa + 661 gggaggaagg taccgtggag atatcaatgt acttttagtg ggagacccct ctacttccaa + 721 gtctcaaatg cttcaatatg ttcacaagat agcaccgaga ggaatttaca cttcaggaaa + 781 agggtcttct gctgttggtc tgaccgccta tatcaccagg gatgtagaca ctagacagtt + 841 tgttctggaa tctggtgctc tggtgctttc ggatggtggt atctgttgca ttgatgagtt + 901 cgataaaatg tccgattcta caaggtcggt cttgcacgaa gtaatggaac aacaaacaat + 961 atcaattgcc aaagcaggta ttatcactac gctgaatgca agaacatcaa ttctagcctc + 1021 tgccaatcct gtcaattccc gctttgatgt aaatttgcca gtggttcaga atatcgacct + 1081 tcctcctcct cttctgtcca ggttcgattt ggtctactta attttggaca aagtggacga + 1141 aaaagctgat cgcctactag cacaacatat gacacaaatg tacttggaag acactcccga + 1201 gaatgtctcg gaatatgaga ttctcccaat tcatattctg acatcctaca tccaatatgc + 1261 caaagaaaac ttcacgccag tgatgacgga ggagggaaaa gtggagcttg tacgtgctta + 1321 tgttgaaatg cgaatgttag gagacgatcc cagatcatca gagaagagga taacagccac + 1381 taccagacaa ttagagtcaa tgatcagact tagtgaggcc cacgccaaga tgcgtctttc + 1441 agaaacggtt gatttgcaag atgttcggga gtccgttaga ttgatgaaag cagctatcaa + 1501 gaactatgcc accgatccta agacgggcaa gattgacatg actatggtga tggctggacc + 1561 gacaccggtg gagacgtaga tcgcattgtt acataagcat ggtgtggagt atattatagt + 1621 tgtcctcgat cccgaccctc ggcaacatct cggatctcat ctgcctttgt tcctttgagg + 1681 ttgattctgt aagtagcttt aaccacagtt cactatactg agtatggatt ccaagccatt + 1741 gtctggggtg tcactagcgg aagctagtaa cttgaatctg gatccatctg tacagctgag + 1801 gtccaatagc tctatacaag aaaactatcc ggatccagct aatgtataca cggagcaact + 1861 aggtcattcc ccatcagaga gggacacact tctcccgcag agccctaatt acaatgctac + 1921 gagtccttcc caaggtgctg gccgatcacc tttgtcgaag aagaaaagaa cgcgttcact + 1981 actttctacg gacaagttga agtccttaaa cacgaaacta ggaaagtgga ccagagggct + 2041 ttcatacaaa tggtggatag tacggtcaaa ggatgtagaa gggcagccta gtgagatcct + 2101 tttcagtgtt ttcatggcac caccttatgt gcagcctctt agaagacttc cagcgggagg + 2161 gttgatgaat atgggtccaa cttcaagaga agattttgca catatagtag atgacgttat + 2221 cgatgccata gaacagggga taaaaccaac tagaatttca caaggctctt caggatcata + 2281 ttttatgtac aatacgcagg ggaagatagt gggagtgttt aaaccaaagg acgaggaacc + 2341 gtatggaccc ttgagcccta aatggaccaa atggattcat cgaaacttat ttccttgctt + 2401 ttttggacga agttgtctaa tccctaattt gggatatatt gcagaatctg cagcgagtct + 2461 tttggatcgc cagttgcagt cttttattgt tccctacaca gacacagtgc tactctcgtc + 2521 cagtagtttc tactacgcat tttgggacag gtgtactcac gcttggtcta agaagccgta + 2581 tcgcaagaag gtgggttcat ttcagttata tttaaacgga tacataggag cagatgagtt + 2641 cttcaaaaag tatcccttgc cagctgacaa aggaaggagc ctattgccat ttttacccga + 2701 taaacacaag aagaaaaaaa cttccaaaaa gagacaaaga ggtgatacta gacattctat + 2761 ttttgacaaa gacactgttt ttgagtggaa tagggatacc ttacaacaat tacgagaaca + 2821 gctggaaaaa ctggtaattc tggattacat catacgtaat acagacagag cttttgacaa + 2881 ttggatgatc aaggtcgaat gggatgaata cttagatgaa gaggcgaacg aggcttataa + 2941 gaggccgaac ttgaaagtta gagcaataga ctccgggctg gcattccctt ggaagcatcc + 3001 taatgagtgg agatccttcc cttttggttg gttgtatctt ccaacatcag tgattgcaag + 3061 gcctttctca gagagaacca gaaggcatta ccttcctctt ttgacttcca aagagtggtg + 3121 ggaagaaact tcagtgctat tccgagaaat gttttcgaga gatacagagt ttaaggagag + 3181 aatgtggaga cgtcaatggg ccgtactaaa gggacaagct ttcaatgtgg ttgaaaccct + 3241 taaaattcca ggtcagagcc cattagatct tgttcaaaaa accagaataa tggtctggga + 3301 taatgtcgtg gagatcccag tttcctacgt tcctagagac attgatatat ataatgactc + 3361 tcctgtttgg acataccaaa attatgatga agagtactgg agctccaaca ttgctcacaa + 3421 ctcaccagga aggtatcatg aacacgaacc aaccacacca gagtctgagt gtttggatga + 3481 tcccttttct tcggctgcgt ccactgatcg tggaggttac gcaattagtt caaatgcaaa + 3541 tactcctgga cgggccaaca ctgattccat tcaaaagccg accacggcta caagaagact + 3601 catcgtggag aggttagaaa ctatcacttc caaaccacct gttttcacct ggtgttaaga + 3661 tgtagagatg aggtcctcgc tatcttattg ttttttcaag gccgtttttc tcttgcaatc + 3721 agtcatagat tattgcaagt tgtcaaagct ttgaagcggt atggtaaccc ctgctaacaa + 3781 gattatatcc attcagtcac atgttgcgca tgggtatgtt ggcaacaaag ttgctggttt + 3841 tgtactacaa tgccagtatt gggatgtgga cttgttgaac actgtcaact tttccaatca + 3901 taccggctat ggaagcttca aaggccaagc aacaaccggc gaacaagttc tatctcttta + 3961 tgaaggcctg caggatatca atgtccaata cgacgcgatg ttaacaggtt acattcaagg + 4021 agcagatgga gtcgaggcga tgggcaaggt gtgcttggat ctgaaagaac gaaccccagg + 4081 tatactatgg ttacttgacc cggtgatggg agacgaagga gagctatatg tgagcgcgga + 4141 tgtgattccc gcttatagac gcatcttggg ctacaaaaaa gtcgacatta taacgcctaa + 4201 ccaatacgag gctgaactac ttgttggttt tagcattaac aacactgatg atttgaggaa + 4261 agccttaaag gtctttcacg aggattttaa tgttatgcat gtggtcatct ccaccttttc + 4321 gttcactaag aataaggatt ttttctactg tgtcagttcc accaaaacct cttacaagaa + 4381 gcctaatttt ttcaagatac catacatgga cagttatttc acgggagtag gagatctttt + 4441 ttctgctctt ctggttgaca agatatatag actgcccggt ggagaaccca tagagcctgc + 4501 agtgagcaac gctttgacaa tcatggagaa agtgttggac gttactcgac ggctgtgcgt + 4561 agataaactt ggcgttgccg tacaaggaaa gatcggagat gccgagacca tgaaggagtg + 4621 cgaacttaga atcgtagagt gccggcaatt ctacacgatg aaagatagaa atttcaactg + 4681 tgagacaaag attttaactg attcacaagc atagagtcaa aatagcataa tattcaatac + 4741 agacatccaa cgtcgacatt cttttctttt ttttttcctg taagacttct ctaggtcagt + 4801 ggtgctccgc gtagcatgca ttttccataa ggaactggtt cgtgttttca cgcacacgag + 4861 gcaaaattaa cttcttatct gtgacacata caaaggtcaa aaataaaaaa ttaatccacg + 4921 tagaactgca ttgtgacagc attcgtttct gcatttgaac ctccatcgtg cgtgactaag + 4981 caaaggcgac gcctacgtct ctagtcttcc taccaagccc tttcacccaa tcgtaagttc + 5041 caccaaaatg taaatgacta aacctcacgt gatcatatct atctagcata tcatgctaac + 5101 aaaagtctgc agactgcaga cgtaaatatt ttcctttccc atcattattc cctgtcaatt + 5161 aacagccaaa ggacaatgaa cccattggat gtgataggtt cagacgggaa taaccatgtg + 5221 tccaagcaac tgcctttaaa aacggcgtcg tcctgcttta acagttcctt ttcttcgttg + 5281 accaagcaat tcactccaga gcttttgaaa tcggacaatg agagcgttga aagtctagcc + 5341 aactatccat tactgacaga caatccttcg ttggtacacc aatggaatca tgagtattct + 5401 gttgtctgtg tgagcgttag ttcttcccgt ggattactgt tctgtggcac tcaagacgca + 5461 aagattcttg tgtttgatct gaacacatat gaaaagattc acgttttaca ggctcatgaa + 5521 ggtgccgttt tgtgtttaga aatatcagca aatgagaagt ttcttttctc gggaggaagt + 5581 gactctcttc tgagaatttg ggacttggaa accatgactg aacggttcac tatttattca + 5641 ttaatggaca ttggcgacat ctttagcata acttggatcc aagacttgaa catggttttt + 5701 tttggaactc aaaatgcttg tatattgtac gcttatgtcg aggtagacgg ttcctggaag + 5761 aacgacccaa gttttctgcc ggcaaacaga tatgacaact tttttgattc gaaaggtcca + 5821 ggcggaaaca tgaaccccaa acaaagtaaa aagaacaaac agcacacttc tccattggtc + 5881 gaggtcgaca cgtataatat tttacgatat gcgcacaatg gttacgtgta tgctatgcaa + 5941 tcctttaaga gaactccaga aactgtggag atatttatta acattcccaa tatttataat + 6001 catatcctag tctcaggtgg aggggatggt ctcgtgaaac tgtggggtgt tggttcagat + 6061 agatccgtag tggcgttgca tgaacttgat aacgaggatt ctgttctcag catggtcatc + 6121 tcagggtcgt ttctttatgc tggattagta gacggacaag taaacctttg ggatttggga + 6181 acttttcagc taatcaggtc caccaagacg gatgaagggg atgttctttc cttagcactt + 6241 tacgccgatt gccttttcaa gggaactgaa catggtatca cgaaatggaa actgcaagga + 6301 gctagaagaa cagattgggt gactcatgaa ggatatgctc ttactgtgaa actttttgaa + 6361 aggcaaggaa atccctatct tatcacaggc ggagttaata accgccttgc gttgtggtct + 6421 ttggatgggg tttattctgc atctaaaaga cgatcacttt cattatctaa aaagtcaatt + 6481 ctaccattgg acaacgactc tttattacaa acactagcca aatttgtgtc ctataaaact + 6541 gtttcgaagc ttcctcaatt ttttattgac gattcccgaa gatgtgcctc ctttttggtt + 6601 aatctactga ccagctttgg ggctactgct cagctaattc ccgtgaagaa cggtaatcct + 6661 atcattcatg catgcttccc agcacaagta attaattctg ctaaaaagaa accaagccga + 6721 attctctggt atggtcatta tgatgtggta agtgcggatc aatccaacgg ttgggttcaa + 6781 gatcccttta agatgtctgc catggatggg tatttatatg gaagaggtgt aaccgataat + 6841 aagggtccac ttttagctgc aatttattct gttgcagagc tcttttccca agatgcatta + 6901 aagtcagatg ttgttttcct tattgaaggt gaggaagaat cagcctcttt tggtttccag + 6961 gaagccgttg gagcttataa ggacgttgtt ggagagattg attggatctt ccttagtaat + 7021 tcttattgga ttgacgatca ccttccctgt ataaactatg ggttgcgtgg agttgttggt + 7081 gtcaaagttg aaatatctag tgataaacct gacaggcatt ctggggttga tggaggagtg + 7141 tctagggaac cggccgttga tctcgtaaaa ctgatttcta aattaacatc tgatgaagga + 7201 aggatacttt tgccagggtt ttttgatggc ttgaatccac cctctgaaga agaggaaaaa + 7261 gactatgaac gaattttgga gagagcaaag ataaaatcta gtaaagaaat gttgatggcc + 7321 aaatggagat atccctcatt aactgtgcat aaggtgacag tttccggtcc aggaaacaat + 7381 acgatcattc cacaaatggc atcagcagct atatcattac gcataacacc agaacaaaat + 7441 ctagaatcgg ttaaaaacat gcttgtatcc ttcttaaagg ataagtttaa ggatttgaag + 7501 acagagaatg aatgcaagat ttctataacc catgaagcag agccatggtt aggagatcga + 7561 agaaatactg gttttcaagt actggaaaat gccattatca acgaatgggg cattgaacca + 7621 ttgtatatca gagaaggagg atctattcct tccattaggt tccttgaaaa ggcctttggt + 7681 gccccagcaa tacattatcc ctgtggtcaa gcttccgaca atgcccactt agataacgag + 7741 agactgagag ttcggaatct ttacaaatct agaaatatct tgaacagggt tttccaaacg + 7801 ttgtaattta tttgtgtgag tcaataattg ataaaaatac aaagagtaaa taaataagag + 7861 ctataaaggt ggtgtagcaa atagtagtaa aataattgct tcaacttagc caaatcgtct + 7921 tctttaacac catcagcaat cttggatctc caatcctttc ccctttcaaa tccgtttgag + 7981 gctgtttgat agtccatgaa ggctttgtag atgaggtctt tagaagtctc cacgaatggg + 8041 ccgtgttgaa caataggctg gtctaaaatc tgtcccgcaa cgagaacaaa ctcagcagga + 8101 gaagtagcat cttctgggac ggagccggta atcttgtttc cattcaagtc aaagaacaga + 8161 gcattgaact tatcatatgt tttgttgttg atttcaagac taccgtcaag taaatagatg + 8221 aaggagttgt agttctcacc aacgctttgt tcaaatgatc ccccgggttg gacagtatag + 8281 tagtaatagt caacaggaga atacgacaaa tcttggaagt tttcgacccc ataggccttt + 8341 cctgagataa tcttaactgt gactttatca tttggagtta ctgtcgggat ctctgaggcc + 8401 cttaaatctc ggtactcagg ttcactatgt ttaagatgct ttggtaggtc aacccacagc + 8461 tgcattccaa ctatgttttc tcctgatttg ccttgaactg gcatttcggc gtgcataata + 8521 cctcttccgg ctctcatgat ctgacaatcc ccggcattca agatcccaac cttgtcgcta + 8581 gtgaaatcct ggtgggcgaa ttgacctttc gtcatatacg taatggtctc ttgcccacga + 8641 tgaggatgat cagggaaccc agcacttggg tcaacgttga aatgatctag cagtaagaac + 8701 ggtttgaaat ttctcatttg catggagcca attgacctac ggactttggc acccacacct + 8761 tctgagactt cattgcaata gaaacttttt aaaactgaac gagacatgtt tgatgatgaa + 8821 agacaagttg aggggtattt ataccttttc cttgcttagt taaccttact aaggagttct + 8881 tacataggac tcgctaccag aagggctcat cagaatcatg catatcgaac cttcgcgaat + 8941 attccatatt actaacaatt actaccttct agctatagtc gaggtggaga agcactgcgc + 9001 ataataggct gcataatact tttacggagt aagctgactc agcatttgac atctcagggt + 9061 ctatttgtca gttatttaag tttacgccat tattgtagaa gacttcaaat actatttttt + 9121 tccaaaaaag ctcaataggg tggattgggc cttcttagat gatttgccct tgacggtccc + 9181 aactgtgggt gaaggcttcg aactggacga tttggggttc gatgatttgt ctgtgcttat + 9241 ctttgtattt ttaactgtcg taataaagcc gtcttcatca acataactag tgatcgcctc + 9301 ctttgactgc tccacttcat tttgtgaggg ctcattactg gccaccgggg ggttaacttc + 9361 ctgaatggaa gtgtcaaagt cagaggcaag gtcaacatcc atctgatcca cgggattcgc + 9421 atcctctctt gcatgcgctt ggtcaccacc ttcatcctcg tcatcgtcaa ttacaaacaa + 9481 actatcttca tttttgggcg gggcagactc ctcttgaata acctgtgtgt cttgcatctc + 9541 gtcatcacta tcagtgaaca tggcagccaa ttcttgcctc tctttgttga tctcttcggt + 9601 ggtctttttc cttggaggct cgttcaacgg gaaggaatta tcatcttcta tgtctccagc + 9661 cacaatcgat tcttttggtt cttttctaga aacgtatgaa attttagatt tggagtttgg + 9721 cttagctttt gaagtcggaa tggtcttttg tactgaggca gaggatttgc tgttttgggg + 9781 tttcctagat acgtatttgg acgtaatgga tgggatagtt tctgttttct tgggaggttt + 9841 tggactttgg ctctttggat ccggagagtg ttttggagcc ggttgtttta ccacgtccac + 9901 ctttggccat tgttcctcta catgctcaat ttgttcagca ggttgttctt tgtgaaatgg + 9961 actttcaata atgcctagct ttctttgcaa ttctgcattt aaccactcgt ttcgcctcat + 10021 tccttccata ttggcaactt cctgggcacc aacgccacta gttgacaatg aatagcaagc + 10081 cacagaaaga accttctcgt atccctgctt cacagtctcc agatcctgtt taccgaccaa + 10141 cttaatatct aggccattct tgatgcctga tactgcgtaa atgatttcca gtttctcatc + 10201 tttcttataa aactcagcta gttcttcctt tgagcggcgg acatcaatgg aaagctctct + 10261 actgagcatt ctataggtca cgggcaactt ttcttcatag agttttgtcg ccagataact + 10321 cgctatttgc gtcatttggt gaaagttctg ttgagaggaa gaagcgcgtt ctttttttgt + 10381 aagagctcgt acgaaagact ggggttaacg cgttcctgat tcaactcaat tttcagaacc + 10441 cagctgtgaa catacggtgc aaatctacga aagctacttg gtaaatcatc tatgtaccag + 10501 ttttgcggta agtaattcgt gtttagctat tggaggccaa tcagctggct gagccatcac + 10561 tctttgaaga agattctttg gacggacgat gctttcttct tcgcgcacct ttgcaagttg + 10621 gtccatgtag tccaccagct aaggcctttc taacatgctt tctcttttat aagtagattc + 10681 tttgacacag aaacaattac agacaagtca ttctgaccgg ttattgccaa atagccgacc + 10741 gttattttct tctccatctc gtcaatgcta ctcttctcgc gttcattggc aaagctaagg + 10801 tcgttcgcca accataatca acaaatcctt caagcaaaaa aatcttcacc aaaccatctg + 10861 atactacatc atggcacagc taacaccagc agagattgag gtcgcaaaga agttcgactt + 10921 gacctccaag ataattccct tcttggaccg tcatctgatt tacccactca ttgaaaactt + 10981 ggacctcaca tacgatgaaa agaccatcaa agaactctca tacaatcttc tcagggatac + 11041 ctacatgaac aagttcatca acgacttgaa cccagacaag gagatttctc aagatgtctt + 11101 gacgaagcaa aaggaaattg aagccaaatc tgaagttttg gaagccgaaa caaaggaaac + 11161 attgaacttg ttgagtaaga aagaagtgca agaacaattg aaatctgaca agaatcacaa + 11221 tagaagatat ttggagtctc agcatggcat cactgaggat aagattcatg ccttgtatga + 11281 atatggacag attcagtaca acaaaggtga ctacgttatg gcaagcgatt tgttggccaa + 11341 ctttcgtatt ctgtctacaa acaacgagct aaacgttagc agcacatggg gtcgtttggc + 11401 ttgcgaaatt ttgttattgg aatggaataa tgcgttagaa gagctgtcaa agctgaggga + 11461 gcttatcgat tcaagaacct cttttaacga tccactctta cagttataca acagaacctg + 11521 ggttatccac tggtctctgt tcccttattt caagactgcc aatggattag agactctgtg + 11581 cgatcttttt ttcagttcgt cttacctgtc caccatccaa gcttcctgtc catgggtgtt + 11641 gagatacttg gttgttgctg tcatttctaa caacagcaag aaattgaaag atctggttag + 11701 agtcactgct caagaaagct accagtacgc ggatcctttt actaatttga ttaaagcatt + 11761 atacttggac tttgattttg cccaggccag tcagcacttg aacgactgtg aagtgatttt + 11821 gaagacagac ttcttcctga acaacgaaga cgagaacctt cctcttattt ccaaaaaatt + 11881 cattaccaac gcaaagaaat taatcataca ggtctatgtg aaatgctacg gaaggatcag + 11941 tttggaagca ttgtccgaga ctttgaattt gaccaagcaa gagctgaagg accttatcgc + 12001 ttctttggac ttgaagaatg ctacacttga cgatgaaaag ttgatcatta atcacacgtc + 12061 gaccaagatt tatcaacagg ttagcgataa agttaagtca ttgggctaca aatccaacca + 12121 gctacttgaa aactttgcta aatagaattg tattcactat gtacatttat gtctgaagga + 12181 aaagttaaga aaaaggctac tatcactcat tattaagagc ttgtagaaac agtagcgttg + 12241 ttacgtttaa ccggtcttgg aacaatcttg tatggatgat ctctcttctt gaaagtgttt + 12301 atgtcattcc tcattctagg taggttctcc aaactcttgg ggtccgagta aaactccttc + 12361 ttacaaattt caacaatttc acggaatttt tcctcaccgt tttctctgtt atgtagcaac + 12421 ttgtcaacgt tcttttgagt caaaggatta attgcgatat tctgtagctc caatctggcc + 12481 actatcttgg cagtgtacca caatttcatc tccctttgag tgttgtccac tagttccatt + 12541 ataacctggg gagccttgtc gttcattctt ggttctaggt ttagtattct ggtgtagcca + 12601 ccagctctac tttggtatct tggtttgaga acattataca actttggaat tgtgacatta + 12661 ggttcaaata tatcagccaa aatgagcgac ttgtcgtagt tcttcttggc cttcgtgatc + 12721 aagttttcca ccagcgcttg agttttttta gcacgtgcct tggtcgtaat gatggactca + 12781 ttttttatta aggatgaggc caaattccgc agcattgccc attcatgttt gactgatcgt + 12841 cctaaaccca tgttggtgaa aagaaaaatg tgtagacaaa aaagttgtgc tggggtcgag + 12901 aagagtctag gaggagaaga aaaaaaaagt cggaagcaac ttgggaggga ggagcaaaga + 12961 catttgacct gctagggggt tacggctctc cttccacctc tggtgaactt cgcgacctcc + 13021 aataaaaaca caacgtcttg agtttcacct cactccatac aacagaattg acatgggtgg + 13081 aagaatatac gggttcctgg ccggtgctct gtttacctcg tcccttacat atcttgcacg + 13141 agaacaattc cagtctgacc aagttcggat ttcaacaagg ctgcgctcct atcaaaaact + 13201 cataaacgaa ggtgaccaac tgaaactcac ggacaataaa ctagaatacc agacaagacc + 13261 atggaaagag gcattcaaag acttgtggaa cgaggaggtc attaaaacag tcaacagaat + 13321 ttacagcatt agatggtacg aggatgctaa gtatctggtg gataaagttg agggtaaata + 13381 gatcaattaa gttttcgaca ctacttatct ttttgttctc tctcgggaga tggcgatgat + 13441 gatgacgatg gggatattct gctttgtttc ttgaagtagt ctcgtatttg tttgttaacg + 13501 aacatagagg caattggtgc aaaaatgctg aaaaggaatg aaattatcac ctggataacg + 13561 ccatagtacc tggggctgcc ccctaaagat gcactcatca gcacataccc tatgaaatct + 13621 gtagtcacgt actgataccc actttgcaag gcgttgtaga ttattttgca acattgttct + 13681 gtggagattg gtgacgatgg gccctcgatg atcctagtga tttctggttt tgatttctct + 13741 tcctccagga acccctcact taaagtattt cctggaaata tgcattcaac tttgatattg + 13801 tgtatcgaca cttcttgacg tagtatgtca ctcaatgatc gcaatgctgc cttcattggg + 13861 gcatactgac cgtatccaat gaacgaatag aatgccagta cagatgaaaa aaacaccaag + 13921 tgccttttgt agggcttttc tacctttgtc attaccttga gcgcaacatg tgagaagtac + 13981 aacgctgtct tgtaattgat atcgattcca ctgctcagag tcttttcatc aagctctaag + 14041 aaaagtccgg ggatggagga gccagcgcaa cagaaaacta tgtcgggact aaaaccaact + 14101 tcctctaaaa cacgctcaca ctggtcatat ttggagatat ctgctgccac gtaagaaatt + 14161 gtgttgccct tctcggtccc gtgaatatca atagcgtcct ttactacctg ctttagtaag + 14221 gattctgttc tagccacaat cacaacggaa catccttttc catacaaaag tttagcaaac + 14281 tcggctccaa caccctggga tgcacccgta ataattgcct ttttgttggt gacatcaaaa + 14341 ttatcaaaca ttccagttcc ctctacactt tgtatgagaa tgatagctga aattgtgcac + 14401 cagatgttag aagataaggt cgtgtcatga actaatatca tgaattccga gggtggctca + 14461 acaactattc acgtgacttg gacgttggaa gttgaggtgg ttggtggatg ttgcacggag + 14521 tatcatttgt aagcatgaaa tcagtctaaa aaacttgcag aatagcagag cggttcggaa + 14581 attcattcaa aaccacctcc tcagattgga tctgccctac tctgtttagc tctgggagat + 14641 tttctcggtc gtgttctttc gctggtctac ccacgctata ggaatcgctg tgaacgctac + 14701 cttcttccca acttctcggt gactattata agccattccc actttgtttt caagcaccaa + 14761 caacccaccc ccaccttatc tactccatct tgggtgtccc cgcgcctgtt gcaaagtccg + 14821 aaccatagaa cccccgacct ttgtcccact aaccctcaga cacccctcgg aagtcaggga + 14881 gaaaccactc cgaagtacat taatcatccc tcgtattctc gacggtgccc attttcttta + 14941 taaaaaggga gacacaggtt gcttcactaa ctctagactt gtattctaca tccactctac + 15001 acaatgtctg atctcttagc tatcaacact atccgtctat tggctgtcga caccgtggcc + 15061 aaggctaact ccggtcaccc aggtgctcca atgggtctgg ccccagctgc tcacactttg + 15121 ttcaagcaaa tgcgtttcaa cccaagaaac ccagcatgga tcaatcgtga tcgtttcgtc + 15181 ttgtccaacg gacatgcttg tgctttgttg tacaccatgc tatttttgta tggatatgac + 15241 tacaccattg atgacctgaa gagcttcaga cagctcaact ccaagactcc aggtcatcct + 15301 gaggctgaac taccaggtgt cgaagtcacc actggtcccc tgggtcaagg tattgccaat + 15361 gccgttggtt tggcaattgc tcaagctcag ttggctgcca catacaacaa gccaaactac + 15421 gaattgttca gcaactacac ttacgctttc ctaggtgatg gatgtttgca ggagggtgtt + 15481 gctcaagaag ccatttctct tgccggccat ctcggagacg gtttaaagct aattgctttc + 15541 tgggatgaca atcaaatctc cattgatggt gataccaacg tctctttcac tgaagacgta + 15601 cctgctaagt ttagagccca aggttgggaa gttctgagcg tcaaggacgg caacgatgac + 15661 ctcgaaggta ttgctgctgc tttggccaag gcaaagacca ccaacaagcc aactttgatc + 15721 agattaccaa ccatcattgg ttacggctct cttcaacaag gtactcacgg tgtgcacggt + 15781 tctccactga agcctgatga catcaagcaa ttgaagaaga agttcggatt tgatccagaa + 15841 caaaactttg ttgttcctag agaagttact gaatcttacg ccaaacatgt tgccgacaac + 15901 cagcaagttg aggtcgaatg gaacaaactg ttaacagctt acactaagga gtatccagaa + 15961 ttgggtcagg agttgcacag aagattggat ggcaaacttc cagaaaactg gcagaaggct + 16021 ttgccaacat acacggttga tgacaagcct gttgcctcaa gaaagctgtc cgaaatagtt + 16081 ttgaccagca tcgagaagga attgccagaa ttggttggtg gttctgccga tttgactggt + 16141 tctaacttga ccagatggcc agacgctgtt gacttccagc caaaatccac aggattaggt + 16201 gacttttctg gaagatactt cagatttggt gtcagagagc atggtatggg agccatcatt + 16261 aacggtatct ccgcttatgg tgccaacttc aaagcttacg gtggtacttt cctgaacttc + 16321 gtgtcctacg cctccggagc cgttagattg tccgctttgt ctggacaccc aattatttgg + 16381 gtcgctacac atgactcgat tggtctgggt gaggatggtc caactcatca gcctatcgag + 16441 actctggccc acttgagagc tcttccaaac ctcatggtgt ggagaccagc cgatgggaat + 16501 gaaacttctg ctgcctactt gagggctatt gagtctaagc acactccttc catcattgct + 16561 ttgactagac agaacttgcc tcaactagaa cactctagca tcgagaaggc tgccaaaggt + 16621 ggttacactg tctacccagt cgagaaccct gatatcattc tggttgcctc tggatctgaa + 16681 gtttctattg ctattgacgg tgccaagaag ttaggaaccg aaggtgtcaa agcttcggtt + 16741 gtttccattc cagacttctt cactttcgac tctcaggcta gatcttacca attatcagtc + 16801 cttccagacg gtgttccaat aatgtctgtc gaggtcatgt ctaccttcgg atggtccaag + 16861 tactctcacg agcaatttgg tatcaacaga tttggtattt ctggaccagg ccctgagatt + 16921 tacaagttct ttgagttcac tgctgagggg gttgctgaca gggcttctaa agtcgtccaa + 16981 ttctacaagg gaaaggaact tctatcgcca cttaataagg cttttgagtc tgttcatgcg + 17041 tagtttgtgc gcctttaggt agttagttaa ttagtaagtt catagtgcgg gaagaatagg + 17101 ctgtcttaga atgctcgaca aagttaccag gattgcgagg attatttatt ggagtgaata + 17161 cttgtaattt attttgcttc cttcttactc tcctcttcct tcgactcatt atttgccacc + 17221 ctcaaagatg gccccgatat ccgttgcgtt tgtatgtcta ggaaacattt gccgaagccc + 17281 catggctgag gcggtgttca cccacttagt caaagaaaaa ggactcgact ctaagttcaa + 17341 aaagattgac tcctttggaa cttcaggata ccatatcgac gatactcctg atcaccgttc + 17401 cgtggcgtgt tgcaagaaac atggagttcc tgtgaaccat agaggtcagc agatctcgcc + 17461 ggacgacttc taccactttg actacatact ggccatggat gaatcaaatc tctccaatct + 17521 caaacgcata cagcccaaag actccaatgc cgtagtcagg ctctttggag actacagaac + 17581 ggacaagtcc ttccacagga ttgtggagga tccttactac ggcgggtctt ctggatttga + 17641 gagaaatttc aaacagatta cgcatttcag tgaagaattc ttaaacaaag agttatagat + 17701 tatagattat caacttttca aagatacaac gtttccaact tgtccttctc aaaagtaaaa + 17761 tcgtcttttc tcctgggaag ccatgtctcc tggtaatcaa agtatttcca gttgctcttt + 17821 tgttgaacgt gctcttcaat aggcggagga gtttgattag cttcgtcatt attgagcagg + 17881 aaccaggtct tgagctcttt gtggtacttc cagccccttc tatgcaactc cttcgccgta + 17941 ttaatttgta ggaaactgcc tgagttgtcg aataccttat gttcatcagc tgcattctcg + 18001 tagctgtgat aatagaaaca gtagaataaa gtctccaaat caaagttctg taaaatcttt + 18061 gccgagttca taatctccaa caaaggttcc tgagggaacg aaatatgggt agggtgtggt + 18121 tgtctaggga tatacatgtt tggcacatct gcatcaaatg agtctggaca atttaacagt + 18181 gaagaattaa gcagttgata catgttgtcc atctcttcag gggtcttttt aatcggctta + 18241 ttgagacatt ccttcttgac tccatccaaa ttagcaataa gattgtttgc aattttcaag + 18301 gacgattcag atgttggagc gtcaagacca ttgggatgag tagtcgttga cgacaaagaa + 18361 tccaatggta gagaagaaga ggaaactgcc ggatgtgcag ttgcggctgt agttgcagtc + 18421 ggagtggttg aatgggtgga cgatccaacc ttcgttgatc ctggtggcac acttgcggta + 18481 gctgctgtac tggcaacctt agaatatttc aacttgggcg tcagcacagg ggccacagca + 18541 ggcttaagat ttgattgaat tccagttaat tcgttatgag aatgtggggg agtcgcagca + 18601 gctgatcttg caggagatgt tcttgtgagt ttgttgagca aaacagatgc attggagttc + 18661 gttgaggtga cattggagac agatcctgtt gatgagttaa tagcagcagg agcggtcttg + 18721 acggtgctgt cagaagttga accttgattt accgcagcaa aattactaga tgcactggca + 18781 cttggagact cgttatctga tacattttcg tcattttcat ctttaccttc ttcatctttt + 18841 gaaaggggtc cagaggcggc ggcaaacaag aacccatctt caatttcatc cagtcccaat + 18901 tcatcataaa taccatcatc ttcagcaaaa tcggcatcct ggttagattc gacgtaatac + 18961 tcaatatcct cttgtatgcg ctggatttga tccgcctcca aattaccatt ctgaagcaat + 19021 cttagtatag tttgaagttt ctcctgatgc cagttatttc tatccaagga ggactgtagt + 19081 tcggcaattt gatcggtctt agagttatcc agtttcttcc ctcgtttgcc actactctgg + 19141 atttgatcta tctgagcttc caaggcttca ctctgtcttt ccaactcttc aatcatggac + 19201 tccacaaact tggaggtctc tgacttttcc ttttcccttg gatcgacttt attcatgttc + 19261 agtccctcct tactgaacgc ctttgtcttc atttctttct cgacctcttt gaatcgctcc + 19321 atctcatgtt caatcaattt tctgtgttcc atcaatcctt tcttctcctt gacttcattt + 19381 cccgccaacc atattttgat ttggtctctg gatcgttgta gttttttgat ttctcttttc + 19441 agatcacttt ctaatttttc cttctgagaa gagctctcgc atgcttgtag tttatcatag + 19501 acataatcga actcttccag accttctttg acttttttga acacacggtc aatctctcta + 19561 aacgggggac atatgttagt gtctgatttc ttttccttgc gacttgacta gaaaacaaag + 19621 catctttgtc acttagccat taatggtaca cgataactta ctgttgtaac ttcctttgag + 19681 acatgtgtgt ggtggttaag aactgtcttc tatactatgt tgtcgttgtg ttctcatgat + 19741 gatgtcacgt gaacgggttt tctcccaatg tcggttcatt attggcagag cacacgacta + 19801 ttgggtttct tcatatcgaa ccccatcgct tccccaactt taggccatgc actactggtt + 19861 atcttttacc gacaactgaa ttatttttca gactcaactg agtcatttac agtgaggtta + 19921 ggactcattc aaacgaaacc caacttgtct tcatattttt tttcacttag acggattccc + 19981 cgcactctta agaacgaacc atgagtgaag agaacctaaa ttactgggcc aatatcctag + 20041 acggcccaac actaagtgtt cttcctcgag attataaccg gcctgtagcc ggcaaagtga + 20101 tagaagccaa caagacattt gacatttcag acattcttcc cttcttgaac aaagccaacg + 20161 agccatctgt cacccagttt actgctccac tggctgtgtt tgccgtcttg gtctacagac + 20221 ttaccggtga tgatgacatt gtcatcttga ccgattcacc aaagaaacaa aatctcccct + 20281 ttgtcgtcag acttcaagtt gatccttcca agtcatttgt cgatgtttcc aagcaagtag + 20341 gcgaacaata tcttgagagc ttggagcgtg caaccccgct gaaagatatt gtaacccatc + 20401 ttaaagagtc caaacaattg ccaaattatc cccccatttt caggctaagt ttccaaacag + 20461 ccaagaaggt tcaacaactg tcaactctgg tcgagggatc tacgagagac ctggctattt + 20521 ttttggagaa taataccagt atcaatattt actacaactc tcttttgtac acccacaatc + 20581 gtattgcata tttcagccaa cagttttctt ccttcattga cgaagttaac aaagctcctg + 20641 aaactccaat aggtaagatc tctctactaa ctgagcagca gtctaaactg ctccctgatc + 20701 ccactgcaaa ccttgattgg tcaggatata gaggtgctat ccaagacatc ttctctgata + 20761 acgcggagaa atttcccgac agaacatgtg ttgttgaaac taagtcattt ttgaacccca + 20821 attcccaaac tagaactttc acatacaagc aaatcgacca agcttccaac attgttggaa + 20881 actacttggt gcatacaggt atcaaacgtg gagacgtagt catgatttat gcctaccgtg + 20941 gcgttgatct gatggttgcc gttatgggag tacttaaagc tggtgccacg ttttctgtta + 21001 ttgatcccgc ttatcctccg gccagacaga acgtctatct gcaagttgct aaacctgctg + 21061 gtctaattgt cttggaaaaa gctggcgttt tggatcagct ggttgaggat tatatcaaga + 21121 acgagctaag cttggtttct cgtatatcaa atttgaaaat tgaagccgat ggtaacgttc + 21181 tgggtggaga cgtggatgga aaggacgctt tatacgacta ccaacaattc aaaactagaa + 21241 gaactggcgt tttggttggg cctgactcta atcctacatt atcgtttacc tctggatctg + 21301 agggcatccc taaaggtgtt cttggtcgtc atttctcctt ggcctattat tttccttgga + 21361 tgtcaaaaac tttcaacctt tcagagaatg acaagttcac aatgttgtct ggtatcgctc + 21421 atgaccccat tcaaagagat atgtttactc ctttattttt aggtgctcag cttttgattc + 21481 ctactagtga tgacattggt actccaggaa aattggcaga atggatgcaa acctatggtg + 21541 caacagtgac ccatttgact cctgctatgg gacagctgtt gtctgcccag gcaactaagg + 21601 aaattccttc ccttcatcac gccttttttg ttggtgatat ccttaccaag agagattgtt + 21661 tgagactgca aactattgct caaaacgtga acatcataaa catgtacgga accacagaaa + 21721 cgcaacgtgc agtttcgtac tttgagatac cttcaagagc ccaagattcc actttcttgg + 21781 aagttcagaa ggatatcatg ccggccggta aggggatgca taatgttcag ttacttgtag + 21841 tcaacagaca cgatagatct aagacttgcg caataggtga agttggtgag atctacgtcc + 21901 gtgctgctgg tttagctgag cagtatagag ggcagcctga ccttaacaaa gaaaagtttg + 21961 tccccaactg gtttgtatct ccatctaagt gggtagaaga agataagaaa atctcaaagg + 22021 acgaaccttg gagggaattc tacttaggac ccagggatag actctataga actggggact + 22081 taggaaggta tctacctacc ggagattgtg aggtcagtgg tagagctgat gaccaggtta + 22141 agataagagg attcagaatt gaattggggg agattgacac ccatatctct aggcatcctt + 22201 taattcgtca gaacgttact cttgttcgta gggacaaaga tgaggagcca attcttatct + 22261 cttatgttgt gcccaaagaa acacccgaac tggaaaactt caagtcgtca tctgacgatc + 22321 tggacgattt gaatgatcca attgttaaga gtttattatt gtacagagaa ttgataaaag + 22381 acctaaaagc acatttgaag aaaactttgg cctcttatgc tatccccacc attattgtcc + 22441 caatggcaaa gttgcctctg aatcctaatg gtaaggttga caaaccgaag ttaccctttc + 22501 cagatactgt ccagcttgct gctgtagccc aaaagtcctc tgctgaggtt gatgactctg + 22561 aatttaccac cacagaacta cagatcaagg atctctggtt gcaagtactt cccaatccac + 22621 ctgccagtat ttcgttagaa gactcatttt tcgatcttgg aggacactca attttggcta + 22681 cgagaatgat tttcgaactc aggagaaaac ttgcagtcga tttgccattg ggtaccatct + 22741 tcaagcaccc cactgttaag cttttcgcag cagaggttga tcgtgtcaag aatggtgacg + 22801 aagttcagtt tgcggacaac aagcaggaga gtacttctgc tggatctgac gaacaagttg + 22861 ttgactactt tcaagatgca aaggacttgg tttcaagtca attgctagac tcctataaat + 22921 ctagattggc tctttcaaat gctgagctga tcaacatttt cttaactggt gctactggat + 22981 ttttgggctc ttacattctg aaagatctct tggagagaga cttggatgtc caggtctatg + 23041 cccacgttag agctaaagac gaagagtctg ggcttgaaag attgcgcaac accggtaagg + 23101 tttacggaat ttggaatgaa gaatggacta gccgtattaa ggttgtcatt gctgatctca + 23161 gtaaagataa gttaggtcta tcaggtgaaa agtatgctga gctagctaac actattgact + 23221 tgatcataca caacggtgct ctggttcact gggtctatcc atattccaag ttacgtgatg + 23281 ctaatgtcat ttctacaatc aatgtgttga acttggcagc ttctggtaaa cccaaacagt + 23341 ttggatttgt ttcatctact tcaactttag acactgaaca ctatatcact ctttcagaca + 23401 cgttaacaga acaaggtgag gatggtattc cagaatctga tgatttgctt ggatcttcca + 23461 agggtcttgg aactggatat ggacaatcta agtgggcagc tgaatacata attcgccgtg + 23521 ccttcgagag aggtttaaga ggtgccatta ttcgtccagg gtatgttacg ggccactcta + 23581 ggactggtgc ttgtaacaca gatgacttct tgttacgtat gttgaaagga tgtgccgaac + 23641 ttggaaagtt acccaacatt tctaacacgg ttaacatggt cccagttgat cacgttgctt + 23701 tagttgttac tgcatcttct cttcacccta ctgcagaaga aggtcattgt gtggtacagg + 23761 tgacagggca tccaagaatc cgcttcaacg agtttttgaa cgctttgaat gactatggtt + 23821 atgaagtaaa gttaactgat tatgttgagt ggaaacgtga cttggaaaga tttgttgtgg + 23881 atcaatccaa ggacagtgca ttgtatccat tgctccattt cgtgttggac aatcttccac + 23941 aagacactaa agctccggaa ctagatgaca aaaatgcaaa agatattctt agcggagaca + 24001 ccagatggac aggatacgat ggttccaagg gtagaggggt agattctgcc caaacaggta + 24061 tctacattgc ctacttaata aagacaggtt tccttccccc tccgtctaag gaaggcaaga + 24121 aaccgttacc agaaattgag atttccgaag aatccttgaa attgattaag gaaggcgccg + 24181 gagctcgtac cagtgctgcc tagttctata tgtaagtgat attaaactca gttcataaac + 24241 aaaaattgta ggtctgaagg tgtcaatctg ctgatagcag catcatcttg gttaatggtc + 24301 gcatgaatca tatttgcctt tttatcttgc aactcgatga ttctggactc aatgctatct + 24361 tctatacaaa atctggtaat cttcacaggc ctatgttggc caattcgatg aacacggtca + 24421 ccagattgcc attcaaccga aggattccac caagggtcaa gaatgaatac ttgtgaagct + 24481 tcacataagt taagtgccac acctccagct ttcaaagaca ccaaaaacac ctctacggac + 24541 ggagtttcca taaagtgctt gatagtactt tctctttgga gaggagacat tgaaccttgc + 24601 aatttaacag tttcaaaccc tgctcttttc aaacgccatt ctaccaggtc caacatactg + 24661 gtaaattgag agaaaacaat cgatttgata gtgacacggt cacttctaag atgaaacaac + 24721 tcctccacca aggcttcaat cttggttgaa gacctccatt cacctcccat tctaatacga + 24781 ttcacaatgc ttcccttttt aataagttcg aggtccactt ctattgctgg accttctaag + 24841 tctatgctta atgccaagtg acatactggg cactccagtt tgtttgggtc tccgttgaaa + 24901 ccttccacat attcggaaac acacaagcga cagaatttgt ggtgacattt actttcaata + 24961 ggctcttcag cctcatcatc acacaattgg catacaatga ctccttctgg cataccagaa + 25021 ctatcgatgc tgttggtacc aactcttctg agtaccagat caggatggtc tgcaagttga + 25081 cgcatccgag taatcagtgt aaagatgttg gcatagttgt tcagaacaac cccctccgca + 25141 acatagtcat tgaactttct cttactgtcg gaatacaagc ttgcatacaa gtccttttcc + 25201 tcctcattga atctatcacg gcggatctcg acaattctgg gaggaagacc caagtcgtca + 25261 gcccgctgaa ctttggttct tctcagcatt atatttttca ataataatct gatattcttg + 25321 aagctctcca acccgaggcc ttctaccccg tacttctgaa tatttttcaa catgaaatgg + 25381 ttgaaaaaat tggtgtgtaa catgggagta tgtccacatg tgtcacaaca tttccaatta + 25441 gtgaatttcc actccgtgga tcggcaatca cacttagtgc agaaatactc acagaatggg + 25501 tacagtttca taaaacgaat tagagaatac atttctccaa ttctattctg tagcggagta + 25561 cctgacaagc accatctctt ctctgtgtct agagaatttg cagctttggc tgtcccgctt + 25621 tgtctgtcct taatattgtg ggcttcgtct aaaatgaccc tataaaaatg cgtattgtgc + 25681 aaaggactgg gttctttcac cagtccacgt tttcgtttga atccatagtt ttgcttccta + 25741 taaaccgatt caagaaccga ataagttgtc agtatcacat catattcctt taactcttcg + 25801 gcactctttc ctctattttg accatgaaag accccgacct tcagtatccc attggtatga + 25861 agttctatct cacttttcca ctgcattagt gccaccgtgg gtgcaataac cagattgggg + 25921 gacttagttc tgtcatgcat aaacaacgca atagtctgga tggtcttccc cattcccatc + 25981 tcatctgcca gtacaccccc accaaactcg ctctcctcct gcttgacgag ccagttaaga + 26041 ccttcaagtt gaaacggcaa gagagtacaa gtcattcctt cgggctgagt ggcttttttc + 26101 acttcgattt gttcgtgctg gtctaaattc ggaaagacat ctttcaaaga aggatgaatg + 26161 ttgtagagtt tttcagttac tctagtgaaa taaggtactc ttggtttctt cggttttgct + 26221 ggtgtcttcc gtttcttttt gggtctagga gcctcagcct cctcaactac ttccaggtcg + 26281 agttcctcta attcctctgg tatatcaata ttctgttcca aatcgctcag atcactgaga + 26341 tctgaaagac taattgcgtt aacaatactg gcaccattag gtctgtttct gccggtgcta + 26401 gtccctctaa taacaatagc atcttcttct tcatcgtctt cgggtttaat atcgtcaacc + 26461 ttgtctgttc caagcgactc ctggtactcc tcatcttcag attcgtcctt taccttcctc + 26521 ttcctagaag atttagagga tgaggtaccg tttggaggaa gctcatcgtc cgtctcaacg + 26581 taggagacag ctttcttcgc agctcttctt ctcctggcgg gtttcttgta gtctgggtcg + 26641 tccactatga atccgcctgc ttcgcttgct ttggtcatca gtggcaaggt tcttcttaac + 26701 ggctatctgc gaaagtagaa agagcaatat tggggtatcc aaatccggtt ttcctaatga + 26761 ttaggtctct ctcgtaaatg gctccacttc gtaaaaactg cgtctgttaa caacaatttt + 26821 cagggatgac tgtagcctgc cgcaacaaaa aaagttgtta ggaactctgg atcatctcag + 26881 gcaaatatca aggtctagag acgcacctcg tgaaaattta cgcgaaagta gtagaaagtg + 26941 tatagcataa ttgctaaacg cgattacaaa ttgctcagat gaaaaaaata attctataac + 27001 ataaatgtaa taatgaacta taatccataa tgcttactta aggcgataaa tggtctgttg + 27061 caaaaagttc ttccgcgtag tcaaagtccc ataacgagtt ctgcaacttg ttctctagtt + 27121 tagctttctt actgggttcc tcgtcggcgt cggatgatct cttcaaaact tcattttctt + 27181 caggaggggt aggcaacatt ccaaacgata gcgtcttgct gattgccgaa acatctctga + 27241 acactgcatt gattgcagct ggcgtaacct tgctagacca ctcgttggca tttttactgg + 27301 tagacggaga gtccaagggt cgggacgagc ctggggtctt gataaaagat agtggagtct + 27361 gcaagattgc ggacggagtt ataccctttt gagatatagt atctttcttg acagaattgc + 27421 tttccttgga gtctagtagt tgagtctcct catctttgag gtccaacgag cgagataaca + 27481 tgcagaggaa ataagaagca gggtcatcaa gtcccaattc ttttattctc atccgagaag + 27541 tattaatagc ggcactctct gcttcttcct ttgcttggat ctcgttctgt tctttcgtag + 27601 ctacaagatt ctctggtgac tgaacgctgc taggagttgc catcactaca gggcttgatt + 27661 tagccgcagc gttggtagca gccatcctat taccttgcac tttggcttgt ttaccgggtg + 27721 cgccagtaga aggtcccgat acggatgatt tgacttttct tttagcttgc tgaacttgct + 27781 gtataggtac ctgttgttgt agctgctgac gttgctgtgg ttgttgcagc atctgctgcg + 27841 gtacttgctg ttctaatgaa gcttgatagg gttgttgtga atgttgtggt tggggcatat + 27901 tattaggcag ttgttgcata tactgctgag gtttagcatt gggggaagtt tgaacttgct + 27961 gagccaaccg ttgctgagga agagcgcgtt gctgttgccg atgctgctgt tgttggggtg + 28021 gaaactgctg gatttggtta ggcatcaagg agttttgatt gagcataggt gtctgcatca + 28081 agggagacga gtttaattgc tgtcccgaag ctggggtgac tctctgttgc tgactgaatg + 28141 cagcagtatt gttcagagaa gggtcttgaa tccctaaacc tgaaaacatg ttgttagcat + 28201 ttgatccacc catgagcgag tcaggatttg tctgcgacgt gtagagcata ttatttggca + 28261 gctgcttatt tccctggccc atctggggga cttgctggag attagaagtc tgctgctgtt + 28321 gttgctgttg ttgttgcaga gactgaacat tttgtaattg ttgaaacttg cgctgctgga + 28381 gttctttcaa gtaagtaatg tacttgtgaa tctgagtttg aactctttgt aaaatgtttg + 28441 gagtcgccaa atactcattt cgcttcagac tttctaaaac ttccttcagc atgaacttga + 28501 tttgaatcag ccttcttgta ccctcaacat tctttgtggc aataaaaaag ttcggaatca + 28561 aattctctgt tgtgatagag agctggatca tagtcttagc ctgatccagc acagctcgtt + 28621 tctgatcagg tgtgatttcg tttgtcacat tttttagctt tattggtagt tgcaaagcct + 28681 ctgcgtacac ttttcttaaa ttagtccaat cctcttctgt agcttggata ccaggtaaaa + 28741 gctttatagg ttgcttttgc tgctgctgat gcatattagg cacaggttgt tgtgcatttg + 28801 gaagtgcacc gaacatagaa tttgatggta cagattgttg aggttgtttc tgttgctgag + 28861 gtttttgcat aggccttgca ttgttgaatg ttgtaggcaa agtttggttc atcaggggag + 28921 acgtattgac aaatttctgt gcctgttgta gtggcacaga ttgaccagga aagcctggaa + 28981 ccgcttgagg aaccgagttt tgattgttcg cttgttggct tgaaggattt gcagtagcat + 29041 ttttgttttg tagaactcgt ggtaggtaat gtcgttgaat gaacgttttg atgaaagatt + 29101 gttgctgggc cggcgccaat gtttggggca agtcgccagt ttgtttcagc ctctcaatca + 29161 aattcaatgc ttgcgtagta ccttccctaa gcatttcttg tgttatttga agttgtggct + 29221 gctgagtagc agattgttgt ggtggctgct gtggttgttg ctgctgctga ccttgaacca + 29281 atttggaatt gaattgagga ttctgagctt gttgttgaat gtgctgttgg ttgttagcca + 29341 tacgattctg ttgcataaac atctgatctc tttgtggctg gggttgtgtt tggggttggg + 29401 tctgtacctg gggttgctgg ggtggtttct gcatggcatc ttgatgactt cttgcttgta + 29461 acagttgcga gtggaccgtg taaacctgtt taatggtgtt catcagctga ggatttattt + 29521 gcccattctg caacatctgg gttatttgag cccaggtatt gacgccaact ggaagcccag + 29581 gaatacgttt caaaagagcc tcaggtattg gggcagtttt aagattgact ctttggtcat + 29641 tggagaaatt attcatcatg ggacgctgcg gttgctgttg ttgctgttgt tgttgcggtt + 29701 gctgttgctg attatttttc atatactggt tttgctgttg atgttgctgc atttgtggtt + 29761 gaacgggaat attctgttga cccatgctct gcattccgtt cagagtagct gcagggtcag + 29821 gggcattagc ggccatggag gaacgaccgt taaccgcagc ctgcttgatg ctggatactt + 29881 tgtttctcaa catgtcaacg tactccttct ttgatctagc attgctgaac gcccattttt + 29941 caaagtcttc agccaactgt ttggtcttag cgttattaaa ggaattattg ccctgtattt + 30001 ggaagactga ctgtacaata atgtttatga agccctgtcg ttccttcggg ttgagttccg + 30061 agtgccatgg ctgttgtggt aacccgttca tggcaagaca aagggcgatt tgggaatggt + 30121 ggggatgatg gggaaggaaa taaagagagg gaatgaggag agggaatctg agcgatttga + 30181 gactgaacta atgcggatga tgatgcgatt cgagacaaga acgaggggga tagattagac + 30241 aaaatatcat gatatattta catgcaaaat cattgggggt agtgaacctt gcagatctga + 30301 ggtaattgtg gtccacagtc tggaaggcga tctgaaagga gcgtattgta tcatagcgga + 30361 tatagtacga cctgcttctg acgtattgtc aacgagctgc accaggggcc taagattata + 30421 aatcaggatc tcaaaggggg agcatgtagt gaaagccaca cggagaaatg gagtcagaaa + 30481 cctacttaaa gagagtttgt gagtgaagaa tgaatttgtt gcagattata tcgtgtacgt + 30541 gggatccaca gctcagctga gttgaccggt tagagcttca ctgagcaggg ttgtttgcta + 30601 ggatgccaaa ttgggaattt ttcaaatgca agctggatga cagagaatta gtaacagccc + 30661 aatccgcctt ttcttttttg tctttggatt ctcttgttgt catgatatgc gactgtacgc + 30721 tctttactaa aggaagatgt tcagactcac gcatcgattg gcgactagct ggcgactagc + 30781 tggcgactag ctggcgacta gctggcgact agctggcgat gagtgatact cactcgccct + 30841 tggtgcttat cgccccatac aaaaatgact cttgcgtagg aagttttggt aggggcgcca + 30901 ggtttagtcc cacttggtcg tgtcaatcac ccgctggatt taccagacgt tccttttgct + 30961 ttcttctcca atcaacagat ccctcttcaa ggcagttggc atccttctcc tcaagatggg + 31021 tgcttgggta atggatgttt ttcatgacca cacctcactt gacttcttgg ataatttact + 31081 aaagtcacaa gatcaggtta aatttgttgt ggattcgttg gctgctccgg taccacaaac + 31141 tcttgaggat ggcgagattg attgcagtga atcctttcaa aagttgatgt ctgccatttt + 31201 tcttgcaatt tggctggact tcgatacaaa gattccctta gccaaagcga agtactctgg + 31261 ccacatcact gatggtatcg aagaaaccta tgacaaagtt aaggattccc cagatttcca + 31321 ggaactcgaa aagcagggac aatttttcaa aaatcaagcg aaacaatggc ttaaatcttt + 31381 atctgaaaac cctgaattat cggagctctg tgaattatgg ataaaggatc cagaaaacta + 31441 caaaaagtgg aaggaaaaca tagattgggt aattgacttt gtctcctgaa gaaaaagggt + 31501 ctacttgtgt cagtcgtatc attttattct ggtgccttta gagcttgaac tcctcctagg + 31561 atcagatact ttaggatacc gtttatctct gtctttgtaa ttgctctata gcttctttta + 31621 tcaacaaaga aagatctccg cctgcatctc caccgctttc tatagcacat aaattatttt + 31681 gcaacgtctc gagagtaggt aacattgaca gttctgtagt ctctttaaag atcacgataa + 31741 cattatccaa cacacctcca aagtaagcgc agacctgaac aaaaatctcc ttcttttccg + 31801 cattcgatga ggagttattt gatgtcagtg ttgacgccaa tggagacact ctggagattg + 31861 tttccttaat ttcggtttgc gtccacttga ggtcattttg caccatcgta tcatccttca + 31921 ccgcatcttg ctgaagagtt ttggaaatgt aatcatccaa gagcctcgcc aaaactaaca + 31981 atccatggaa attacgtagt tgagagttct cctggtccat acttggtagt caaccaattg + 32041 cttacagaaa atgctcccaa ttaagtaaaa ttgagagttg aaaaatacaa ttccaaattc + 32101 gtttcacgga atttttccaa acatcaaata attcgaattt attcacttaa ataatacgcc + 32161 tattttatac atatgaatag atcaaatctt tccggcttcc atttcaatat ccagcagctc + 32221 cagggacgtt ttccttcccc ttcaaagata acaaaatctc cttaaatcta gtcttgtccg + 32281 cttcatcagc accaaaagaa ctgttcttct tcaacttcag cagctctact gttctatccc + 32341 acacacttcc ctggtcgaag aaactgtccc tcttggcaat gaacttctcc tcgtcctcct + 32401 tggtggcctt tagagatttc tccttcttgt cgttatagtt gacataaaag tcatccacat + 32461 ccttctcagc ctgttttttg atctcttcgt gtttcttggc agcaacctca tctctcttgg + 32521 agatctccaa ttcagtacgc tctttccact cttgaattgg cttgctctcc ttcaagtcca + 32581 aattatcaaa agtgctgtgc agtggagtat gtgcctcttc ttcgggagca tcttctactg + 32641 gaatactctc ctcttgatca gcatctactt tgggaaagtt gctctcaaat tcgtcgaact + 32701 cgtccacgtt gtcgtcagcc aactcttggt ctctctcggt tgtgaattca tcgcccaaaa + 32761 gttccttttc tctacttaaa aagtcacctt gcgaaggaga ttcaccggaa gatgcgccgg + 32821 tgtcgacgtc tttcaactct ggaaacttgt cagccattgt gaagaaatta tgcggcaagg + 32881 taaacagggg aggtagtgag agaagacgat ctggaggttt gggggcccca cctaccaatg + 32941 aaggtttcga gggtcctaac tcccgttgga cttccctcta gtttgccatt cctccccttc + 33001 gaggctgaac gctctcgtat ttctccacca acaaccaaac cattgatact tactccagac + 33061 catgtcttac tcaaaggata tagttttgga aaagcttgct agtttggaag aaacccaaat + 33121 tagcattcaa tccatcggac aatggtgtct atttcaccat agacatgctc ccgaaaccgt + 33181 cgccatttgg agtgaatttg taggttccac ccaaaccaag aagcttgcgg ggctctatct + 33241 ggccaatgaa attattcagc aatcgagagc taaacgaaag actacatttc tagatgagtt + 33301 tgccaaggtg ctaccatcta ctttagagca aatctatccg agtatgatct ctactcacca + 33361 ggcgaaactg aagcgaatta tagatgtctg gagtcaacgt aagatatttg actcaaacct + 33421 gattcataga ctttatcaga gcatacagga tcaaaaagct tataacggtt tatcctcgtc + 33481 tagttcaaat tctccaccaa tcaattctgg ggatttggct cctgagattt cctctctatc + 33541 aacgctgttc aacaaaatct caacattgaa gtcttcaacg tctctggtcg ttaatcagat + 33601 aaatgaacaa tactcaagtc tattcgactc tgaaacatta ccaggaactg atatttattt + 33661 aaaacaactt ggagatctat caaccttaat cacctcagcc agatcaaagt cacaggagac + 33721 ccaagaatta cgagagtcca taataaatga gctgaagaaa ctgattcaag tccaagagtc + 33781 gtggattacg aaagatgcag agtcttcggg ttctctggat gagaaacttg ccacagttca + 33841 gcagaaagaa tcagagttga aagaattcat aaacgatgta gaagaagaag atggtgtacc + 33901 tcaatatgcc gcttcaagtg atgaagaagg cgacgaaaat gtgtcaaaaa agagaaaaat + 33961 ggagagccca ccaactgaaa cagttgattc tggcgaacag ccaactaacc cagtccaccc + 34021 tcagctttcc tccatcttag agagtctatc tagaacaact ggactaacac cagaacctgc + 34081 ttctacttcg gacgagtcag caacagcaac gcagaagcaa gatgaaacac ctgtttcttc + 34141 atctataaat cctgctctag ccagtttgct gtccaaactt aacggttaat tcttaatgtc + 34201 ttccccaatc acttgagtac gaactatgta ttatataatc aggcatcttt tctttttttc + 34261 tttttttttt gtctctcgct tggatcccaa caccatattt cagatctcct gatgactgac + 34321 tcactgataa taaaaatacg gcttcagaat ttctcaagac tacactcact gtccgacttc + 34381 aagtatgaca tttcccttgc tacctgcata cgcaagtgtt gcagagtttg ataattcctt + 34441 gagtttggta ggaaaagccg tgtttcccta tgctgctgac cagctgcaca acctgatcaa + 34501 gttcactcaa tcgactgagc ttcaagttaa tgtgcaagtt gagtcatccg ttacagagga + 34561 ccaatttgag gagctgatcg acaacttgct caagttgtac aataatggta tcaatgaagt + 34621 gattttggac ctagatttgg cagaaagagt tgtccaaagg atcccaggcg ctagggttat + 34681 ctataggacc ctggttgata aagttgcatc cttgcccgct aatgctagta tcgctgtgcc + 34741 tttttcttct ccactgggcg atttgaaaag tttcactaat ggcggtagta gaactgttta + 34801 tgctttttct gagaccgcaa agttggtaga tgtgacttcc actgttgctt ctggtataat + 34861 ccccattatt gatgctcggc aattgactac tgaatacgaa ctttctgaag atgtcaaaaa + 34921 gttccctgtc agtgaaattt tgttggcgtc tttgactact gaccgccccg atggtctatt + 34981 cactactttg gtggctgact cttctaatta ctcgttgggc ctggtgtact cgtccaaaaa + 35041 gtctattccg gaggctataa ggacacaaac tggagtctac caatctcgtc gtcacggttt + 35101 gtggtataaa ggtgctacat ctggagcaac tcaaaagttg ctgggtatcg aattggattg + 35161 tgatggagac tgcttgaaat ttgtggttga acaaacaggt gttggtttct gtcacttgga + 35221 acgcacttcc tgttttggcc aatcaaaggg tcttagagcc atggaagcca ccttgtggga + 35281 tcgtaagagc aatgctccag aaggttctta taccaaacgg ttatttgacg acgaagtttt + 35341 gttgaacgct aaaattaggg aggaagctga tgaacttgca gaagctaaat ccaaggaaga + 35401 tatagcctgg gaatgtgctg acttatttta ttttgcatta gttagatgtg ccaagtacgg + 35461 tgtgacgttg gacgaggtgg agagaaacct ggatatgaag tccctaaagg tcactagaag + 35521 gaaaggagat gccaagccag gatacaccaa ggaacaacct aaagaagaat ccaaacctaa + 35581 agaagtccct tctgaaggtc gtattgaatt gtgcaaaatt gacgtttcta aggcctcctc + 35641 acaagaaatt gaagatgccc ttcgtcgtcc tatccagaaa acggaacaga ttatggaatt + 35701 agtcaaacca attgtcgaca atgttcgtca aaatggtgac aaagcccttt tagaactaac + 35761 tgccaagttt gatggagtcg ctttgaagac acctgtgtta gaagctcctt tcccagagga + 35821 acttatgcaa ttgccagata acgttaagag agccattgat ctctctatag ataacgtcag + 35881 gaaattccat gaagctcaac taacggagac gttgcaagtt gagacttgcc ctggtgtagt + 35941 ctgctctcgt tttgcaagac ctattgagaa agttggcctc tatattcctg gtggaaccgc + 36001 aattctgcct tccacttccc tgatgctggg tgttcctgcc aaagttgctg gtcgcaaaga + 36061 aattgttttt gcatctccac ctaagaagga tggtaccctt accccagaag tcatctacgt + 36121 tgcccacaag gttggtgcta agtgtatcgt gctagcagga ggcgcccagg cagtagctgc + 36181 tatggcttac ggaacagaaa ctgttcctaa gtgtgacaaa atatttggtc caggaaacca + 36241 gttcgttact gctgccaaga tgatggttca aaatgacaca tcagccctgt gtagtattga + 36301 catgcctgct gggccttctg aagttctagt tattgctgat aaatacgctg atccagattt + 36361 cgttgcctca gaccttctgt ctcaagctga acatggtatt gattcccagg tgattctgtt + 36421 ggctgtcgat atgacagaca aggagcttgc cagaattgaa gatgctgttc acaaccaagc + 36481 tgtgcagttg ccaagggttg aaattgtacg caagtgtatt gcacactcta caaccctatc + 36541 ggttgcaacc tacgagcagg ctttggaaat gtccaatcag tacgctcctg aacacttgat + 36601 cctgcaaatc gagaatgctt cttcttatgt tgatcaagta caacacgctg gatctgtgtt + 36661 tgttggtgcc tactctccag agagttgtgg agattactcc tccggtacca accacacttt + 36721 gccaacgtac ggatatgccc gtcaatacag cggagttaac actgcaacct tccagaagtt + 36781 catcacttca caagacgtaa ctcctgaggg actgaaacat attggccaag cagtgatgga + 36841 tctggctgct gttgaaggtc tagatgctca ccgcaatgct gttaaggttc gtatggagaa + 36901 actgggactt atttaattat ttagagattt taacttacat ttagattcga tagatctaac + 36961 cggcatctaa catccagtgt ttctaatcta gtgaatcgag atcaagtctc actctgaaca + 37021 taataaataa ggtctaaccc catggaatta catgtcccct tgggttctga gattgtctta + 37081 cccggtgggg aaagagccat actcaagttc gtaggaaatg tggagtcaaa gtctgggatt + 37141 tttgctggtg ttgaactgat tggtcaaatg agtggaaaag gaaagaattc tggagagttt + 37201 aagaacgtgc agtactttac caccaaagtc cctaattcag gcatattttt gccctatcaa + 37261 agacttctgg agacaagtaa catgcaacga cttcaagcag agacaccaac gaagacaaaa + 37321 cgaaatgttt atgtatctcg ctcaccatta gctgtttcca atcaacaagg gttgaaacga + 37381 tcatcaaagg agagtagccc gagcactgtt gcaggcaatg aaggacaatt gcacagtttg + 37441 aagactgaaa atacccatct ttcacagaaa tgtttgaagt tagaaacaca gttacaagag + 37501 tgcacggaag ttctcgagtc tatggagaag gtcattaaag accattacga accagccttc + 37561 aaccaaatgg agaaagattt gtctgagaag aatgaaaaaa tttccaagct aaaggtttca + 37621 ttcgacgaac agaagaccga actgctggat attattgatt cccttgaaaa acaagcgtca + 37681 gaaactgaac agctctacac taaagaattg aaaaggttga gggaggaatg tgctgcttat + 37741 aaaaacaagg atactgcaaa ggaaacgaac gaactccaac gtcagctgaa agtcaaggaa + 37801 aaaatgtgtc aagattggga gttgaaatat actcaactta aggattcaaa aagtaaagag + 37861 gaaaacgata taattcaagg ataccagcgt gaaatcgatg atttgaaagc aaaattatca + 37921 agctctcaga aagctcaacc tgaaaaaaac acggaaatag aagagcaatt acaacgattg + 37981 aaagcagaaa atcgatctct gcaacaacag cttgagaccg ccagagagaa ggaaaaaata + 38041 caaccattga cctcaacaac cacagagcaa tcaaccttgc tggatgagaa cgggaacttg + 38101 caaatatttg ttccaaaaaa ctctgatccc gcaaatggaa gaaaaaaatg gtgtggtctt + 38161 tgtgaaaggg aaggacatga tagcgttcaa tgcccttttg agaatgatat gttttaaagg + 38221 ataatgattt tctcgttctt ttattagaaa agaagaacaa attcccaatg aattctccta + 38281 atattatgca gattaaacta cctagcagct acaagactct tggttgttcg tagatggtcg + 38341 gttcaaatcg atgttgcgac gtctcttggt agctgaattc agtttctctt caactggtaa + 38401 cttggaggca atcgaatgga aaacatcctt tattccttcg cctgttttag cacttatttc + 38461 cttgaaaatg agccccaatt catccgcgta ctccttggcc tccttggttg aaaccttacg + 38521 ttcggcttcc aaatccagct tatttcccac caaggccacg acgatgtcag cgctagcctg + 38581 tttctgtagt tcctgaatcc aggatttagc tctatccaag gaagattctt gtgttatgtc + 38641 gtaagcaaca agtgcacagt tggcatttct atagtacatt ggggccaaag acttgtatct + 38701 ctcctggcca gcggtatccc aaatctcaaa tttgattgtg gtcctttcat ctagctgaat + 38761 agtttgggtt aaaaatgcgg ctcctattgt tgactctctc aaatcgtcaa aggagtcggt + 38821 gacgaaacga tgtacgatag aggactttcc aacagcactt tccccttaaa gaatgttagt + 38881 cagatggcaa accacgaata tggaacagcg acgtctaaag aaatacttac ccaataaaac + 38941 aagcttgaac tgggcaaatc tgggctcttg tgtaactaaa tcagccatga tgacaggtta + 39001 gatgtaaggt gtagatagtg gcagagtggg tttgcgataa aagccgtgtt gataggtgaa + 39061 cgaccttgtt tcttttttat ttttctctca actgagacac tagaatcgag aacgaaaacc + 39121 ttttcgcaga ggagatgagt tgagtaaggg tagggctgaa ttgattctga tattttgttt + 39181 ctatttacat ggaatcaacc aataatttaa ttctcgatct tggcaagaat ctctctgtcg + 39241 gagaacaaca gatactcttc atcgttgatc ttgactggag atccaccgaa cgagggaatc + 39301 aacacattgt cgccggcttt gacgatagtt ggttccaatg atccattttg gtttggaaca + 39361 cctggaccag tggcaatcac cgttgcctgg tgcaacttct ccacgttctt ctcgggaatg + 39421 tagataccag aagcagtctt ggtggcggcc ttagctcttt gaacgagaac tctgttcagc + 39481 aatggcttga gtgagttggc tgactttaaa agagtagact tgaactgtta gtaaccgttt + 39541 gcctgctatt gaccaattgg gagtgacgac gacttaccat tgttgttaat gtgctgttaa + 39601 tcgaaagatg gagagtgaaa gaaggaaaaa gggagagaat ccggtaccga ttttttatat + 39661 tggaactttc gagaagttct ggaaatatcc tggggttgtc tggtagtgcc tatgctaata + 39721 gggtccctaa tatgataata ctctatatct atgctacatc ttattcacat actagttgat + 39781 ctgctgcgtg agagaagcta ttgactgttc taggaccttc ttttcaccga aaaccaaaat + 39841 cgagatggcc agcttttgag aatctttggt taccctaatg gctttctcat agtcgttgct + 39901 agtcagtccc ccatcttggt aggcggtaga tctttgcttg caccaattta gaatattctg + 39961 atatgctgcc ttttcaggag attccagagt accgatcttt tccaggaaca gggttttatc + 40021 gtctgcctct ctcagctctt gaaattcagc ctctgaaaga gacaatagtc ttgcgagagc + 40081 ataagtagat tgggaaggcc ttccctccgc attgactctc aattcaactt gccatggtag + 40141 atattctggt tgctcttcct cttcctcttc tccttcatcg ttaccaccat cacatgagtt + 40201 acagcaggat cctggactgg cctgggagtc tccattgcat gattggcatt cggcgtcaga + 40261 gtgatactga tcgtcacctt cctccccatt tttatggcct tccttttctt ctttgtcttc + 40321 caccccttcg ttgtcgtact cctcttgatt taattgagct gtgtaatgca aataatcgtt + 40381 gaacacttcg tatcccttgg aatcccacca gtctttacga tctgggaagt tcttgagctg + 40441 gcttaaagcc tggtctccaa gactcacata atcattgggg ttgttgaggg acgtaaatcc + 40501 atattttgtc aacagggacg tattgtttag atccccatag gtgttgagca attccttgtt + 40561 ctttgggatt gacttgacaa tcttgatatc acagcaaaca tcgggtatca aaagactgtc + 40621 ttcatcgata tcgctcatgt cactatcaga gttatcgtgc ccttcagctt cggaggcatc + 40681 agattcctcg tcagacatgt cttcacgttc cagttctttt tccaacttgg taatatagtc + 40741 ttccgtcacc tcaaatggtt cattattacc ttctttctta ttatcttcca ttccgtcctc + 40801 ggtatccgcg tcatcgtgaa ctttgtcttc ctcgtcttcc tcgttatcac cctcttgctc + 40861 caaatcgctt tctatctcac tgtcaggagc tccatgctct atatggccac actcgtcaca + 40921 actggcacaa aatgggcaaa catctcccaa cgcttcgaaa tgtacatgct cccttccgta + 40981 tgaatcatgg ttgaaaagat cggctcctgg aacaagggcc aattcatggt aattatcaac + 41041 attgaacgac ctagaagcta ttgctaatgt tatagcagca aattccaaaa gtttttcttt + 41101 ggcattgttt tcatcaacag ctaactcagt ggggactttg aggacagatt cgtattctct + 41161 ggcaaacgat acgcaagact caaacagccc ttcagtctct tcttcaaaat tatccaagac + 41221 tgaataaagc tcagttccta ttagcagatt tttcttctca tctggccata aatgaactgg + 41281 aagtattaaa cccttagtat tcttaggttg aattgtttga agatatgcat accatggaga + 41341 atcggagcct aaggacttct catacaaaaa cgccaagata agtcccaaat gactatcagc + 41401 accacattca tggagcaaat tcgaaatgaa agagttcttg ccgcttaaaa tcgactgctt + 41461 ggatactctc agaagaaggt tctcttcatc gtcctcttcg tcatgcccaa tcttttcttt + 41521 agcaaagact cctactcctc caagaggaga ctctcttatg gcaaccaagt cttcattcca + 41581 ataagccttg tttgacgggt ccctaaacca ttctatcagt tgttcagtca tgagtaaatg + 41641 ttagacgtaa gatggtaaac gtgaaaaaaa aaattcatgc atagaacgtt cctgataaga + 41701 acatccgaaa tccatcactt tacctacaac aaaatatact atcttttata taactacaaa + 41761 actaaacttt aaagagttaa tctaccagtg gtaacacatt ggcttcgaag tatccctcgt + 41821 tgacataatt tcctggtggt gagtagttgc ataccacgta ggctccgtaa tagtcattgc + 41881 agtacttgaa agcgcagccg agctttgtgg tgcttttcca aactacttga gtgaaatgtc + 41941 caacacctgg ggtataacct gggttattaa agtcataata ttcaatttca ctgtaccagg + 42001 catcaacagt ccctctggtt gagtaaccat acgctaagtt ttctccgtac agactatttc + 42061 cagagtgaac caaggttccg tcacaagtgt atgcgtcagc atatgcttgg gcggcagcat + 42121 atacttcttc atcccactct aatccgtcaa ctccatgtag agctcttttt atgttgtgtt + 42181 catcaagaat ttgatattta aaagcatcaa agtcggaact tgccgttgga cttatatcgt + 42241 agggagtagt agtagaagaa cctgtctctg aggacgatgg ggttgggctt gttgactctt + 42301 gtcctgtggt ttgtgtaatg gtggaagact ctgaactggt tatcgatgaa ctggttgcta + 42361 gcgagctact accagttgat gattcagtgg cagatgtgga cccagatgtg gaccctgatg + 42421 tctcacttga agattcggtg gtagcggaag tggcaacgct agattcaatt gtcgaactca + 42481 cttctgagct gacagttgca cttccaccag ccagtgtgga agaagtctct tcactaacat + 42541 ctcgagcata tactgtagta taccagactt cagtggtagt atgtgtgttg gtgtaacaac + 42601 attcagcgtt ggccttggtc aatactgaga taattgatag caatgaaatg tgaagtaatc + 42661 tcattatagt tcaaaggaat gtaaaaagtt ggagaactga aatctgatag tattgccctt + 42721 caaaagtagg atatgtgttg tgctttctct tcagacaggt ttagaaatgt aatgtgatac + 42781 aaatatgtta ctatgacccc cattatatat tcgctgcagg tactaagtta cttgaaatgg + 42841 ttggtttcta attgaagata gccttttcaa acttaccata aagttgattc tgtaatgcgt + 42901 atcaactatg taacagcatg tatgtcgcgc atagagaaca aggatggctg gtgaaatctg + 42961 agtgagattt ctccatcggg aaatagtacc tgcactatta tcaaccgcat ataggtttag + 43021 agacggtttt gttatgacga tttggaactt tgactaaacg ttgtagtggc gagttctttc + 43081 atgctgatcg gccttgctac agagctagca ggggtattat gaaactctgg gttcacgtag + 43141 gtggcctggt tctgaaattc cttggattta ggatcatcgt caacaaaaaa gttgatggaa + 43201 ttggacgcag gtacctcttc gagatcagat tcccaatctg agtagttcgg ctgccaatta + 43261 tcctcatgga aggagtcttt gcttagttcc atttgtgtag cactttgttg atcagtagac + 43321 ttgtcagatt ttgatatccc aatgccgaca agcccggccc tctcttgagt tgggggagga + 43381 gtttctattc ccatttctgc ttccagttct ccaacaaacg aggtcaggtc gtcgtcatcg + 43441 tcgccattat cattattatc gttactatcg tcttgaaatt ctagtggtgt atttggtggt + 43501 ctttttgaag caactttggg atgctcagct ttggacacta agatggacga aggcgtgtgc + 43561 ggagtaaggt gcaccttcgg tatagaaacc tcttgcttct tcttatccac actttcggtt + 43621 aaagaagagc tgtttttggg tttgctttcc ttcatatgta tatggaccct attttccaat + 43681 ggttttgttg gtttcaactt tgtttcaagc ttgaaggggg ttacttttct taaagcggta + 43741 tgattggcag tcgcaacata aggcctagag ccactagccg gagaatcctt tcccagtttc + 43801 agcttttcaa acttcgtgag caatttgtca ggcgctctgg acttattcat ccgtagaacc + 43861 ccgttgaaac gatccatctg gaagcgcttt gtgatatcat cgtaaatcaa taaataatca + 43921 tgttgattag tctttccaag ggttccttca aaaactagag gctccttgcg aacattggga + 43981 tctgactcgg ccttcagaat ataattggac gactcctgga ccaactccaa gggatagtcc + 44041 atatcaattg aatcgggttt gaaattgtat ctaactccca agttgacaga atcgtcgcaa + 44101 agcaaagacg aaatgtctaa atcgtactcc ccatccggaa tgtccaatac ttcactcatt + 44161 tgccaacttc ggaataaatg tgcggcaaga gcagtgtgtg act +//