diff test-data/BUSTED/gene2.json @ 0:dd2d60b55e0d draft default tip

planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/drhip commit 15c654c3d27df68a47483031961ace7f5b8d998d
author iuc
date Thu, 04 Dec 2025 15:05:26 +0000
parents
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--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/BUSTED/gene2.json	Thu Dec 04 15:05:26 2025 +0000
@@ -0,0 +1,695 @@
+{
+ "Evidence Ratios":{
+  },
+ "Site Log Likelihood":{
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+    ]
+  },
+ "Synonymous site-posteriors":  [
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+  ],
+ "analysis":{
+   "authors":"Sergei L Kosakovsky Pond",
+   "citation":"*Gene-wide identification of episodic selection*, Mol Biol Evol. 32(5):1365-71, *Synonymous Site-to-Site Substitution Rate Variation Dramatically Inflates False Positive Rates of Selection Analyses: Ignore at Your Own Peril*, Mol Biol Evol. 37(8):2430-2439",
+   "contact":"spond@temple.edu",
+   "info":"BUSTED (branch-site unrestricted statistical test of episodic diversification) uses a random effects branch-site model fitted  jointly to all or a subset of tree branches in order to test for alignment-wide evidence of episodic diversifying selection. Assuming there is evidence of positive selection (i.e. there is an omega > 1),  BUSTED will also perform a quick evidence-ratio style analysis to explore which individual sites may have been subject to selection. v2.0 adds support for synonymous rate variation, and relaxes the test statistic to 0.5 (chi^2_0 + chi^2_2).\n                               \nVersion 2.1 adds a grid search for the initial starting point.\n\nVersion 2.2 changes the grid search to LHC, and adds an initial search phase to use adaptive Nedler-Mead. \n\nVersion 3.0 implements the option for branch-site variation in synonymous substitution rates. \n\nVersion 3.1 adds HMM auto-correlation option for SRV, and binds SRV distributions for multiple branch sets.\n\nVersion 4.0 adds support for multiple hits (MH), ancestral state reconstruction saved to JSON, and profiling of branch-site level support for selection / multiple hits.\n\nVersion 4.2 adds calculation of MH-attributable fractions of substitutions.\n\nVersion 4.5 adds an 'error absorption' component \n\nVersion 4.6 adds support for MSS-type models\n",
+   "requirements":"in-frame codon alignment and a phylogenetic tree (optionally annotated with {})",
+   "settings":{
+     "error-sink":1,
+     "mss":"No",
+     "multiple-hit":"None",
+     "srv":"Yes"
+    },
+   "version":"4.6"
+  },
+ "background":1,
+ "branch attributes":{
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+       "Posterior prob omega class":        [
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+      [0.01651759884459136],
+      [0.02925055929127961],
+      [0.01217462118004102],
+      [0.04856425764989153],
+      [0.02335376908798366],
+      [0.04135654424169535],
+      [0.01721335494628832],
+      [0.01826098626758108],
+      [0.008781414094422619],
+      [0.01555076352482647],
+      [0.006472514015538997],
+      [0.01534294594175388],
+      [0.007378175514105413],
+      [0.01306580710473399],
+      [0.005438229413926055],
+      [0.01559207164907205],
+      [0.007497976053105356],
+      [0.01327795856827995],
+      [0.005526530758038588],
+      [0.02204519218088164],
+      [0.01060117775101382],
+      [0.01877333269084459],
+      [0.00781380661894053],
+      [0.02001283201397348],
+      [0.009623848489980729],
+      [0.0170426073132688],
+      [0.007093446860043523],
+      [0.01681485300040535],
+      [0.008085991904804354],
+      [0.0143192595888557],
+      [0.005959939409601683],
+      [0.01708787828271292],
+      [0.008217285364372072],
+      [0.0145517635478013],
+      [0.006056711836919557],
+      [0.02416007116849923],
+      [0.01161818898347029],
+      [0.02057432977490965],
+      [0.008563414755540757],
+      [0.01095174735555056],
+      [0.008072200842739543],
+      [0.01913496685581441],
+      [0.009201697278655068],
+      [0.01629503140027161],
+      [0.006782292004731834],
+      [0.009351106613197152],
+      [0.01655961626153459],
+      [0.006892417094094173],
+      [0.02749367841825353],
+      [0.0132212670023302],
+      [0.02341317633368553],
+      [0.009744994946783913]
+      ],
+     "Log Likelihood":-522.0390000538857,
+     "Rate Distributions":{
+       "non-synonymous/synonymous rate ratio for *background*":        [
+[0.2134874183278158, 1]
+        ],
+       "non-synonymous/synonymous rate ratio for *test*":        [
+[0.05375692390200871, 1]
+        ]
+      },
+     "display order":1,
+     "estimated parameters":26
+    },
+   "Nucleotide GTR":{
+     "AIC-c":1130.795872905925,
+     "Equilibrium frequencies":      [
+[0.3347619047619048],
+      [0.2033333333333333],
+      [0.2466666666666667],
+      [0.2152380952380952]
+      ],
+     "Log Likelihood":-546.2152441452704,
+     "Rate Distributions":{
+       "Substitution rate from nucleotide A to nucleotide C":0.1157280802219541,
+       "Substitution rate from nucleotide A to nucleotide G":1,
+       "Substitution rate from nucleotide A to nucleotide T":0,
+       "Substitution rate from nucleotide C to nucleotide G":0.1604122535118794,
+       "Substitution rate from nucleotide C to nucleotide T":2.313607104947681,
+       "Substitution rate from nucleotide G to nucleotide T":0.1528462357734212
+      },
+     "display order":0,
+     "estimated parameters":19
+    },
+   "Unconstrained model":{
+     "AIC-c":1135.480989915523,
+     "Log Likelihood":-521.8563486162983,
+     "Rate Distributions":{
+       "Background":{
+         "0":{
+           "omega":224.9667643065964,
+           "proportion":0
+          },
+         "1":{
+           "omega":0.1788885192362742,
+           "proportion":0.5465744472573087
+          },
+         "2":{
+           "omega":0.251168474136212,
+           "proportion":0.4534255527426913
+          },
+         "3":{
+           "omega":0.2024887349695371,
+           "proportion":0
+          }
+        },
+       "Synonymous site-to-site rates":{
+         "0":{
+           "proportion":0.2729752444117259,
+           "rate":0
+          },
+         "1":{
+           "proportion":0,
+           "rate":1.396781922073988e-08
+          },
+         "2":{
+           "proportion":0.7270247555882741,
+           "rate":1.375468981370307
+          }
+        },
+       "Test":{
+         "0":{
+           "omega":223.2365630647954,
+           "proportion":0
+          },
+         "1":{
+           "omega":0.02758628794594435,
+           "proportion":0.1008034141000489
+          },
+         "2":{
+           "omega":0.05377704583904181,
+           "proportion":0.8985911133771098
+          },
+         "3":{
+           "omega":1,
+           "proportion":0.0006054725228412919
+          }
+        }
+      },
+     "display order":2,
+     "estimated parameters":43
+    }
+  },
+ "input":{
+   "file name":"/home/dcallan-adm/Documents/veg/CAPHEINE/work/a4/7d2a9b33d4505019743b214dbd74ff/pretend_DENV1_ref.part_NC_001477.1__capsid_protein_C__95-394_DENV1-nodups.fasta",
+   "number of sequences":7,
+   "number of sites":100,
+   "partition count":1,
+   "trees":{
+     "0":"(PP564823_1_2023_10_06,((PP563832_1_2023_08_28,PP563830_1_2023_09_02,PP563831_1_2023_08_29)Node3,(PP563839_1_2023_09_29,PP563838_1_2023_09_30)Node8)Node2,PP563845_1_2023_10_22)"
+    }
+  },
+ "runtime":"2.5.73",
+ "substitutions":{
+   "0":{
+     "0":{
+       "root":"ATG"
+      },
+     "1":{
+       "root":"AAC"
+      },
+     "10":{
+       "root":"CCG"
+      },
+     "11":{
+       "root":"TCT"
+      },
+     "12":{
+       "root":"TTC"
+      },
+     "13":{
+       "root":"AAT"
+      },
+     "14":{
+       "root":"ATG"
+      },
+     "15":{
+       "root":"CTG"
+      },
+     "16":{
+       "root":"AAA"
+      },
+     "17":{
+       "root":"CGC"
+      },
+     "18":{
+       "root":"GCG"
+      },
+     "19":{
+       "root":"AGA"
+      },
+     "2":{
+       "root":"AAC"
+      },
+     "20":{
+       "root":"AAC"
+      },
+     "21":{
+       "root":"CGC"
+      },
+     "22":{
+       "root":"GTG"
+      },
+     "23":{
+       "root":"TCA"
+      },
+     "24":{
+       "root":"ACT"
+      },
+     "25":{
+       "PP564823_1_2023_10_06":"GGT",
+       "root":"GTT"
+      },
+     "26":{
+       "Node8":"TCA",
+       "PP564823_1_2023_10_06":"TCA",
+       "root":"CCA"
+      },
+     "27":{
+       "root":"CAG"
+      },
+     "28":{
+       "root":"TTG"
+      },
+     "29":{
+       "root":"GCG"
+      },
+     "3":{
+       "root":"CAA"
+      },
+     "30":{
+       "root":"AAG"
+      },
+     "31":{
+       "root":"AGA"
+      },
+     "32":{
+       "root":"TTC"
+      },
+     "33":{
+       "root":"TCA"
+      },
+     "34":{
+       "PP563831_1_2023_08_29":"GAA",
+       "root":"AAA"
+      },
+     "35":{
+       "root":"GGA"
+      },
+     "36":{
+       "root":"TTG"
+      },
+     "37":{
+       "Node8":"CTT",
+       "root":"CTC"
+      },
+     "38":{
+       "root":"TCA"
+      },
+     "39":{
+       "root":"GGC"
+      },
+     "4":{
+       "PP563845_1_2023_10_22":"CGA",
+       "root":"CGG"
+      },
+     "40":{
+       "Node2":"CAG",
+       "root":"CAA"
+      },
+     "41":{
+       "root":"GGA"
+      },
+     "42":{
+       "root":"CCC"
+      },
+     "43":{
+       "root":"ATG"
+      },
+     "44":{
+       "root":"AAA"
+      },
+     "45":{
+       "PP564823_1_2023_10_06":"ATG",
+       "root":"CTG"
+      },
+     "46":{
+       "root":"GTG"
+      },
+     "47":{
+       "root":"ATG"
+      },
+     "48":{
+       "root":"GCT"
+      },
+     "49":{
+       "Node3":"TTT",
+       "root":"TTC"
+      },
+     "5":{
+       "PP564823_1_2023_10_06":"AAG",
+       "root":"AAA"
+      },
+     "50":{
+       "root":"ATA"
+      },
+     "51":{
+       "root":"GCA"
+      },
+     "52":{
+       "root":"TTC"
+      },
+     "53":{
+       "root":"CTA"
+      },
+     "54":{
+       "root":"AGA"
+      },
+     "55":{
+       "Node2":"TTC",
+       "root":"TTT"
+      },
+     "56":{
+       "root":"CTA"
+      },
+     "57":{
+       "root":"GCC"
+      },
+     "58":{
+       "root":"ATA"
+      },
+     "59":{
+       "Node3":"CCT",
+       "root":"CCC"
+      },
+     "6":{
+       "root":"AAG"
+      },
+     "60":{
+       "root":"CCA"
+      },
+     "61":{
+       "root":"ACA"
+      },
+     "62":{
+       "root":"GCA"
+      },
+     "63":{
+       "Node2":"GGG",
+       "root":"GGA"
+      },
+     "64":{
+       "root":"ATT"
+      },
+     "65":{
+       "root":"TTG"
+      },
+     "66":{
+       "root":"GCT"
+      },
+     "67":{
+       "root":"AGA"
+      },
+     "68":{
+       "root":"TGG"
+      },
+     "69":{
+       "Node2":"GGT",
+       "PP564823_1_2023_10_06":"AGC",
+       "root":"GGC"
+      },
+     "7":{
+       "root":"ACG"
+      },
+     "70":{
+       "root":"TCA"
+      },
+     "71":{
+       "root":"TTC"
+      },
+     "72":{
+       "root":"AAG"
+      },
+     "73":{
+       "root":"AAG"
+      },
+     "74":{
+       "root":"AAT"
+      },
+     "75":{
+       "root":"GGA"
+      },
+     "76":{
+       "root":"GCG"
+      },
+     "77":{
+       "root":"ATC"
+      },
+     "78":{
+       "root":"AAA"
+      },
+     "79":{
+       "root":"GTG"
+      },
+     "8":{
+       "PP564823_1_2023_10_06":"GGT",
+       "root":"GCT"
+      },
+     "80":{
+       "PP563838_1_2023_09_30":"CTG",
+       "PP564823_1_2023_10_06":"TTA",
+       "root":"CTA"
+      },
+     "81":{
+       "root":"CGG"
+      },
+     "82":{
+       "root":"GGT"
+      },
+     "83":{
+       "PP563832_1_2023_08_28":"TTT",
+       "root":"TTC"
+      },
+     "84":{
+       "PP564823_1_2023_10_06":"AAA",
+       "root":"AAG"
+      },
+     "85":{
+       "root":"AAA"
+      },
+     "86":{
+       "PP564823_1_2023_10_06":"GAG",
+       "root":"GAA"
+      },
+     "87":{
+       "root":"ATC"
+      },
+     "88":{
+       "root":"TCA"
+      },
+     "89":{
+       "root":"AGC"
+      },
+     "9":{
+       "root":"CGA"
+      },
+     "90":{
+       "root":"ATG"
+      },
+     "91":{
+       "PP563845_1_2023_10_22":"TTG",
+       "root":"CTG"
+      },
+     "92":{
+       "PP564823_1_2023_10_06":"AAC",
+       "root":"AAT"
+      },
+     "93":{
+       "root":"ATA"
+      },
+     "94":{
+       "root":"ATG"
+      },
+     "95":{
+       "PP564823_1_2023_10_06":"AAC",
+       "root":"AAT"
+      },
+     "96":{
+       "PP564823_1_2023_10_06":"AGG",
+       "root":"AGA"
+      },
+     "97":{
+       "root":"AGG"
+      },
+     "98":{
+       "root":"AAA"
+      },
+     "99":{
+       "root":"AGA"
+      }
+    }
+  },
+ "test results":{
+   "LRT":0,
+   "p-value":0.5
+  },
+ "tested":{
+   "0":{
+     "Node2":"test",
+     "Node3":"test",
+     "Node8":"test",
+     "PP563830_1_2023_09_02":"background",
+     "PP563831_1_2023_08_29":"background",
+     "PP563832_1_2023_08_28":"background",
+     "PP563838_1_2023_09_30":"background",
+     "PP563839_1_2023_09_29":"background",
+     "PP563845_1_2023_10_22":"background",
+     "PP564823_1_2023_10_06":"background"
+    }
+  },
+ "timers":{
+   "Overall":{
+     "order":0,
+     "timer":30
+    },
+   "Preliminary model fitting":{
+     "order":1,
+     "timer":2
+    },
+   "Unconstrained BUSTED model fitting":{
+     "order":2,
+     "timer":26
+    }
+  }
+}