Mercurial > repos > iuc > hyphy_gard
comparison test-data/busted-out2-1.json @ 34:5b777002c2de draft default tip
planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit e7a89841d59689e87db592e112f9c8fb5331d954
author | iuc |
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date | Thu, 02 Mar 2023 15:16:52 +0000 |
parents | 659517798cc4 |
children |
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33:659517798cc4 | 34:5b777002c2de |
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1 { | |
2 "Evidence Ratios":{ | |
3 "constrained": [ | |
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19 ] | |
20 }, | |
21 "analysis":{ | |
22 "authors":"Sergei L Kosakovsky Pond", | |
23 "citation":"*Gene-wide identification of episodic selection*, Mol Biol Evol. 32(5):1365-71", | |
24 "contact":"spond@temple.edu", | |
25 "info":"BUSTED (branch-site unrestricted statistical test of episodic diversification) uses a random effects branch-site model fitted \njointly to all or a subset of tree branches in order to test for alignment-wide evidence of episodic diversifying selection. \nAssuming there is evidence of positive selection (i.e. there is an omega > 1), BUSTED will also perform a quick evidence-ratio \nstyle analysis to explore which individual sites may have been subject to selection. v2.0 adds support for synonymous rate variation, \nand relaxes the test statistic to 0.5 (chi^2_0 + chi^2_2). Version 2.1 adds a grid search for the initial starting point.\nVersion 2.2 changes the grid search to LHC, and adds an initial search phase to use adaptive Nedler-Mead. Version 3.0 implements the option\nfor branch-site variation in synonymous substitution rates. Version 3.1 adds HMM auto-correlation option for SRV, and binds SRV distributions for multiple branch sets\n", | |
26 "requirements":"in-frame codon alignment and a phylogenetic tree (optionally annotated with {})", | |
27 "version":"3.1" | |
28 }, | |
29 "background":1, | |
30 "branch attributes":{ | |
31 "0":{ | |
32 "B_FR_83_HXB2":{ | |
33 "MG94xREV with separate rates for branch sets":0.0124534911696585, | |
34 "Nucleotide GTR":0.01178680392701259, | |
35 "constrained":0.0133332678009897, | |
36 "original name":"B_FR_83_HXB2", | |
37 "unconstrained":0.01333097793183841 | |
38 }, | |
39 "B_US_83_RF":{ | |
40 "MG94xREV with separate rates for branch sets":0.02861194347570897, | |
41 "Nucleotide GTR":0.02637179869727959, | |
42 "constrained":0.03221962988361129, | |
43 "original name":"B_US_83_RF", | |
44 "unconstrained":0.03256468480049571 | |
45 }, | |
46 "B_US_86_JRFL":{ | |
47 "MG94xREV with separate rates for branch sets":0.01907096200225401, | |
48 "Nucleotide GTR":0.01766254318226218, | |
49 "constrained":0.0202680273768515, | |
50 "original name":"B_US_86_JRFL", | |
51 "unconstrained":0.02050998211592096 | |
52 }, | |
53 "B_US_90_WEAU160":{ | |
54 "MG94xREV with separate rates for branch sets":0.0228124185259555, | |
55 "Nucleotide GTR":0.0208836028381146, | |
56 "constrained":0.02350080060535386, | |
57 "original name":"B_US_90_WEAU160", | |
58 "unconstrained":0.03169576721730974 | |
59 }, | |
60 "D_CD_83_ELI":{ | |
61 "MG94xREV with separate rates for branch sets":0.02096580136021227, | |
62 "Nucleotide GTR":0.01905599613120992, | |
63 "constrained":0.02146725583386667, | |
64 "original name":"D_CD_83_ELI", | |
65 "unconstrained":0.02163106296740794 | |
66 }, | |
67 "D_CD_83_NDK":{ | |
68 "MG94xREV with separate rates for branch sets":0.01029979658511127, | |
69 "Nucleotide GTR":0.009776698714183414, | |
70 "constrained":0.01035332290986223, | |
71 "original name":"D_CD_83_NDK", | |
72 "unconstrained":0.01033266120816073 | |
73 }, | |
74 "D_CD_84_84ZR085":{ | |
75 "MG94xREV with separate rates for branch sets":0.0311654066957857, | |
76 "Nucleotide GTR":0.02822254903672137, | |
77 "constrained":0.03323755030380494, | |
78 "original name":"D_CD_84_84ZR085", | |
79 "unconstrained":0.03361093648063813 | |
80 }, | |
81 "D_UG_94_94UG114":{ | |
82 "MG94xREV with separate rates for branch sets":0.05961647055090802, | |
83 "Nucleotide GTR":0.05323070232023583, | |
84 "constrained":0.06686538335493719, | |
85 "original name":"D_UG_94_94UG114", | |
86 "unconstrained":0.06754551106553502 | |
87 }, | |
88 "Node1":{ | |
89 "MG94xREV with separate rates for branch sets":0.02629484580500255, | |
90 "Nucleotide GTR":0.02355240508560319, | |
91 "constrained":0.02886080451868769, | |
92 "unconstrained":0.02913820563215103 | |
93 }, | |
94 "Node10":{ | |
95 "MG94xREV with separate rates for branch sets":0.001918758877996093, | |
96 "Nucleotide GTR":0.002230248981703367, | |
97 "constrained":0.001805007516719466, | |
98 "unconstrained":0.001821173275343402 | |
99 }, | |
100 "Node2":{ | |
101 "MG94xREV with separate rates for branch sets":0.003971092177388864, | |
102 "Nucleotide GTR":0.003949360371801276, | |
103 "constrained":0.002472638754288051, | |
104 "unconstrained":0.002387715711685514 | |
105 }, | |
106 "Node3":{ | |
107 "MG94xREV with separate rates for branch sets":0.01135514370835145, | |
108 "Nucleotide GTR":0.01048442975058683, | |
109 "constrained":0.01356000749275525, | |
110 "unconstrained":0.01374972129226249 | |
111 }, | |
112 "Node9":{ | |
113 "MG94xREV with separate rates for branch sets":0.005568732807049801, | |
114 "Nucleotide GTR":0.004986123424162501, | |
115 "constrained":0.00559084970119209, | |
116 "unconstrained":0.005669013080318036 | |
117 } | |
118 }, | |
119 "attributes":{ | |
120 "MG94xREV with separate rates for branch sets":{ | |
121 "attribute type":"branch length", | |
122 "display order":1 | |
123 }, | |
124 "Nucleotide GTR":{ | |
125 "attribute type":"branch length", | |
126 "display order":0 | |
127 }, | |
128 "constrained":{ | |
129 "attribute type":"branch length", | |
130 "display order":1 | |
131 }, | |
132 "original name":{ | |
133 "attribute type":"node label", | |
134 "display order":0 | |
135 }, | |
136 "unconstrained":{ | |
137 "attribute type":"branch length", | |
138 "display order":0 | |
139 } | |
140 } | |
141 }, | |
142 "data partitions":{ | |
143 "0":{ | |
144 "coverage": [ | |
145 [0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405, 406, 407, 408, 409, 410, 411, 412, 413, 414, 415, 416, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, 427, 428, 429, 430, 431, 432, 433, 434, 435, 436, 437, 438, 439] | |
146 ], | |
147 "name":"busted.filter.default" | |
148 } | |
149 }, | |
150 "fits":{ | |
151 "Constrained model":{ | |
152 "AIC-c":6401.571605880178, | |
153 "Log Likelihood":-3164.403373999521, | |
154 "Rate Distributions":{ | |
155 "Background":{ | |
156 "0":{ | |
157 "omega":0.1702532607798455, | |
158 "proportion":0.8127334552706815 | |
159 }, | |
160 "1":{ | |
161 "omega":0.2017838473060485, | |
162 "proportion":0.1774848965120759 | |
163 }, | |
164 "2":{ | |
165 "omega":13.15236788524238, | |
166 "proportion":0.00978164821724258 | |
167 } | |
168 }, | |
169 "Test":{ | |
170 "0":{ | |
171 "omega":0, | |
172 "proportion":0.8358903801628909 | |
173 }, | |
174 "1":{ | |
175 "omega":1, | |
176 "proportion":0.1436055877954064 | |
177 }, | |
178 "2":{ | |
179 "omega":1, | |
180 "proportion":0.02050403204170275 | |
181 } | |
182 } | |
183 }, | |
184 "display order":3, | |
185 "estimated parameters":36 | |
186 }, | |
187 "MG94xREV with separate rates for branch sets":{ | |
188 "AIC-c":6410.490466219016, | |
189 "Equilibrium frequencies": [ | |
190 [0.07535940345366139], | |
191 [0.01443006409728228], | |
192 [0.02915821068672351], | |
193 [0.02954870567752823], | |
194 [0.03219408024958758], | |
195 [0.006164627375802654], | |
196 [0.01245659774045292], | |
197 [0.01262342001471309], | |
198 [0.0276793164843978], | |
199 [0.005300125700761717], | |
200 [0.01070973633984303], | |
201 [0.01085316415297191], | |
202 [0.0418125103783387], | |
203 [0.008006395714089126], | |
204 [0.01617817990958604], | |
205 [0.0163948426631036], | |
206 [0.0409913146415633], | |
207 [0.007849150478922548], | |
208 [0.01586044121725868], | |
209 [0.01607284872448998], | |
210 [0.01751178502783737], | |
211 [0.003353213651232053], | |
212 [0.006775694789785172], | |
213 [0.006866436807635995], | |
214 [0.01505600521072376], | |
215 [0.002882972930821469], | |
216 [0.005825499564956559], | |
217 [0.005903516300053625], | |
218 [0.02274367484777162], | |
219 [0.004355032959661065], | |
220 [0.008800028033786655], | |
221 [0.008917880494044083], | |
222 [0.06143704799998004], | |
223 [0.01176416611541591], | |
224 [0.0237713451467977], | |
225 [0.0240896977132239], | |
226 [0.0262463496652457], | |
227 [0.005025736545566795], | |
228 [0.01015528996016046], | |
229 [0.01029129247081581], | |
230 [0.02256567087217255], | |
231 [0.004320948178469224], | |
232 [0.008731154380523415], | |
233 [0.00884808446536876], | |
234 [0.034087812394816], | |
235 [0.006527245376826684], | |
236 [0.01318932435908579], | |
237 [0.01336595951511979], | |
238 [0.01178447449308153], | |
239 [0.02413128354890585], | |
240 [0.0262916585104385], | |
241 [0.005034412430862358], | |
242 [0.01017282094890981], | |
243 [0.01030905823951665], | |
244 [0.004328407393735399], | |
245 [0.008746226896405704], | |
246 [0.008863358836639712], | |
247 [0.03414665788893068], | |
248 [0.006538513303760755], | |
249 [0.0132120929750345], | |
250 [0.01338903305480236] | |
251 ], | |
252 "Log Likelihood":-3175.995949441886, | |
253 "Rate Distributions":{ | |
254 "non-synonymous/synonymous rate ratio for *background*": [ | |
255 [0.2379324068936849, 1] | |
256 ], | |
257 "non-synonymous/synonymous rate ratio for *test*": [ | |
258 [0.1777604776475358, 1] | |
259 ] | |
260 }, | |
261 "display order":1, | |
262 "estimated parameters":29 | |
263 }, | |
264 "Nucleotide GTR":{ | |
265 "AIC-c":6683.094244259512, | |
266 "Equilibrium frequencies": [ | |
267 [0.4044507575757576], | |
268 [0.1662878787878788], | |
269 [0.2095643939393939], | |
270 [0.2196969696969697] | |
271 ], | |
272 "Log Likelihood":-3320.503280793639, | |
273 "Rate Distributions":{ | |
274 "Substitution rate from nucleotide A to nucleotide C":0.1815218119292989, | |
275 "Substitution rate from nucleotide A to nucleotide G":1, | |
276 "Substitution rate from nucleotide A to nucleotide T":0.08433479296165451, | |
277 "Substitution rate from nucleotide C to nucleotide G":0.1775869374255926, | |
278 "Substitution rate from nucleotide C to nucleotide T":1.184827038118431, | |
279 "Substitution rate from nucleotide G to nucleotide T":0.04288318031815568 | |
280 }, | |
281 "display order":0, | |
282 "estimated parameters":21 | |
283 }, | |
284 "Unconstrained model":{ | |
285 "AIC-c":6400.149223170942, | |
286 "Log Likelihood":-3162.670820660715, | |
287 "Rate Distributions":{ | |
288 "Background":{ | |
289 "0":{ | |
290 "omega":0.1679188282558003, | |
291 "proportion":0.8207520434237199 | |
292 }, | |
293 "1":{ | |
294 "omega":0.2120937673953722, | |
295 "proportion":0.1693698006934513 | |
296 }, | |
297 "2":{ | |
298 "omega":13.84252711122189, | |
299 "proportion":0.00987815588282877 | |
300 } | |
301 }, | |
302 "Test":{ | |
303 "0":{ | |
304 "omega":0.08367159828032572, | |
305 "proportion":0.9533274940567786 | |
306 }, | |
307 "1":{ | |
308 "omega":0.2493792697064242, | |
309 "proportion":0.03716922067476962 | |
310 }, | |
311 "2":{ | |
312 "omega":34.20463703717275, | |
313 "proportion":0.009503285268451747 | |
314 } | |
315 } | |
316 }, | |
317 "display order":2, | |
318 "estimated parameters":37 | |
319 } | |
320 }, | |
321 "input":{ | |
322 "file name":"/tmp/tmpfzf3u9m4/job_working_directory/000/2/working/./input.nex", | |
323 "number of sequences":8, | |
324 "number of sites":440, | |
325 "partition count":1, | |
326 "trees":{ | |
327 "0":"((((D_CD_83_ELI,D_CD_83_NDK)Node3,D_UG_94_94UG114)Node2,D_CD_84_84ZR085)Node1,B_US_83_RF,((B_FR_83_HXB2,B_US_86_JRFL)Node10,B_US_90_WEAU160)Node9)" | |
328 } | |
329 }, | |
330 "test results":{ | |
331 "LRT":3.465106677611402, | |
332 "p-value":0.08841616008911996 | |
333 }, | |
334 "tested":{ | |
335 "0":{ | |
336 "B_FR_83_HXB2":"background", | |
337 "B_US_83_RF":"background", | |
338 "B_US_86_JRFL":"background", | |
339 "B_US_90_WEAU160":"test", | |
340 "D_CD_83_ELI":"background", | |
341 "D_CD_83_NDK":"background", | |
342 "D_CD_84_84ZR085":"background", | |
343 "D_UG_94_94UG114":"background", | |
344 "Node1":"background", | |
345 "Node10":"background", | |
346 "Node2":"background", | |
347 "Node3":"background", | |
348 "Node9":"background" | |
349 } | |
350 }, | |
351 "timers":{ | |
352 "Constrained BUSTED model fitting":{ | |
353 "order":3, | |
354 "timer":14 | |
355 }, | |
356 "Overall":{ | |
357 "order":0, | |
358 "timer":60 | |
359 }, | |
360 "Preliminary model fitting":{ | |
361 "order":1, | |
362 "timer":3 | |
363 }, | |
364 "Unconstrained BUSTED model fitting":{ | |
365 "order":2, | |
366 "timer":40 | |
367 } | |
368 } | |
369 } |