comparison hyphy_sm19.xml @ 5:5f1830cb9135 draft

"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"

4:c60fcdf8f01e

            </repeat>
            <output name="sm19_output" file="sm19-out2.json" compare="sim_size"/>
        </test>
    </tests>
    <help><![CDATA[
This analysis implements canonical and modified versions of the Slatkin-Maddison
phylogeny based test for population segregation. The test estimates the minimum
number of migration events using maximum parsimony, and then evaluating whether
or not this number is lower than expected in a panmictic or unstructured
population using permutation tests.
    ]]></help>
    <expand macro="citations">
        <citation type="bibtex">
            @UNPUBLISHED{slatkin,
                author = "Slatkin M, Maddison WP",
                title = "A cladistic measure of gene flow inferred from the phylogenies of alleles",
                year = "1989",
                note = "Genetics 123(3):603-613",
                url = "https://www.ncbi.nlm.nih.gov/pubmed/2599370"}

5:5f1830cb9135

            </repeat>
            <output name="sm19_output" file="sm19-out2.json" compare="sim_size"/>
        </test>
    </tests>
    <help><![CDATA[

SM2019 : Structured Slatkin-Maddison
====================================
    
What does this do?
------------------

Test for evidence of genetically segregated populations, using a "detuned" version of 
the Slatkin-Maddison test.

Brief description
-----------------

This analysis implements canonical and modified versions of the
Slatkin-Maddison phylogeny based test for population segregation. The
test estimates the minimum number of migration events using maximum
parsimony, and then evaluating whether or not this number is lower than
expected in a panmictic or unstructured population using permutation
tests

Input
-----

1. A phylogenetic tree in the *Newick* format

Note: assumes that leaf names that can be partitioned into sets using regular expressions

For example

::

    ((((((((x_US_x_A_01C:0.0125396,(((((x_US_x_A_01P:0.00887628,((
    x_US_x_A_08P:-0.000190918,x_US_x_A_11P:0.00313157):0.0106883,
    x_US_x_A_14C:0.0103815):0.00311658):0.00120812,x_US_x_A_09P:0.00320468):
    0.0108828,x_US_x_A_12P:0.00732672):0.00596663,x_US_x_A_07C:0.00449846):0
    .00639319,((((x_US_x_A_02P:-2.62303e-05,x_US_x_A_05P:0.00591507):0.
    000156788,x_US_x_A_04P:0.00576826):0.00907366,((x_US_x_A_03P:0.00941548,
    x_US_x_A_14P:0.00866127):0.00229499,x_US_x_A_13P:0.0209192):0.00469629):
    0.0146758,(x_US_x_A_10P:0.000156443,x_US_x_A_15P:0.00578946):0.00472532)
    :0.0103079):0.00733948):0.00228489,x_US_x_A_06P:0.00557974):0.00472981,
    x_US_x_A_04C:0.00478858):0.00105548,x_US_x_A_05C:0.0120259):0.0060905,
    x_US_x_A_12C:0.002911):2.90824e-05,x_US_x_A_11C:-5.79432e-06):4.34574e-
    06,x_US_x_A_13C:-4.34574e-06):4.34574e-06,((x_US_x_A_08C:0.0029538,
    x_US_x_A_09C:-1.31511e-05):0.00296627,x_US_x_A_10C:-8.69148e-06):4.
    34574e-06,x_US_x_A_15C:-4.34574e-06);
    
Which can be partitioned into two groups of leaves, those that end in "P", and those that 
end in "C"

1. Reg-exp 1: `P^`
2. Reg-exp 2: `C^`


Output
------

A JSON file with analysis results (http://hyphy.org/resources/json-fields.pdf).

A custom visualization module for viewing these results is available (see http://vision.hyphy.org/Slatkin for an example)

Further reading
---------------

https://github.com/veg/hyphy-analyses/tree/master/SlatkinMaddison


    ]]></help>
    <expand macro="citations">
        <citation type="bibtex">
            @PUBLISHED{slatkin,
                author = "Slatkin M, Maddison WP",
                title = "A cladistic measure of gene flow inferred from the phylogenies of alleles",
                year = "1989",
                note = "Genetics 123(3):603-613",
                url = "https://www.ncbi.nlm.nih.gov/pubmed/2599370"}