diff test-data/busted-out1.json @ 2:4bf743518e41 draft

"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 3908306ffa6f6cbc7b83303b2d4c581406d2fad9"
author iuc
date Tue, 27 Apr 2021 18:00:33 +0000
parents 7c86ceaf523c
children
line wrap: on
line diff
--- a/test-data/busted-out1.json	Tue Apr 20 19:51:21 2021 +0000
+++ b/test-data/busted-out1.json	Tue Apr 27 18:00:33 2021 +0000
@@ -1,73 +1,73 @@
 {
  "Evidence Ratios":{
    "constrained":    [
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   },
  "Site Log Likelihood":{
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   ],
  "analysis":{
    "authors":"Sergei L Kosakovsky Pond",
    "citation":"*Gene-wide identification of episodic selection*, Mol Biol Evol. 32(5):1365-71",
    "contact":"spond@temple.edu",
-   "info":"BUSTED (branch-site unrestricted statistical test of episodic diversification) uses a random effects branch-site model fitted \njointly to all or a subset of tree branches in order to test for alignment-wide evidence of episodic diversifying selection. \nAssuming there is evidence of positive selection (i.e. there is an omega > 1),  BUSTED will also perform a quick evidence-ratio \nstyle analysis to explore which individual sites may have been subject to selection. v2.0 adds support for synonymous rate variation, \nand relaxes the test statistic to 0.5 (chi^2_0 + chi^2_2). Version 2.1 adds a grid search for the initial starting point.\nVersion 2.2 changes the grid search to LHC, and adds an initial search phase to use adaptive Nedler-Mead. Version 3.0 implements the option\nfor branch-site variation in synonymous substitution rates\n",
+   "info":"BUSTED (branch-site unrestricted statistical test of episodic diversification) uses a random effects branch-site model fitted \njointly to all or a subset of tree branches in order to test for alignment-wide evidence of episodic diversifying selection. \nAssuming there is evidence of positive selection (i.e. there is an omega > 1),  BUSTED will also perform a quick evidence-ratio \nstyle analysis to explore which individual sites may have been subject to selection. v2.0 adds support for synonymous rate variation, \nand relaxes the test statistic to 0.5 (chi^2_0 + chi^2_2). Version 2.1 adds a grid search for the initial starting point.\nVersion 2.2 changes the grid search to LHC, and adds an initial search phase to use adaptive Nedler-Mead. Version 3.0 implements the option\nfor branch-site variation in synonymous substitution rates. Version 3.1 adds HMM auto-correlation option for SRV, and binds SRV distributions for multiple branch sets\n",
    "requirements":"in-frame codon alignment and a phylogenetic tree (optionally annotated with {})",
-   "version":"3.0"
+   "version":"3.1"
   },
  "background":0,
  "branch attributes":{
    "0":{
      "Baboon":{
-       "MG94xREV with separate rates for branch sets":0.001771850913718116,
-       "Nucleotide GTR":0.00167976779100812,
-       "constrained":0.0005055252388761481,
+       "MG94xREV with separate rates for branch sets":0.001772434847524003,
+       "Nucleotide GTR":0.001680040630127455,
+       "constrained":0.001513413708231178,
        "original name":"Baboon",
-       "unconstrained":0.0005398732671668005
+       "unconstrained":0.00161713005248515
       },
      "Cat":{
-       "MG94xREV with separate rates for branch sets":0.2738959056554072,
-       "Nucleotide GTR":0.266075486389923,
-       "constrained":0.1152712488116292,
+       "MG94xREV with separate rates for branch sets":0.2735065373507703,
+       "Nucleotide GTR":0.2660909938917123,
+       "constrained":0.3466844629529476,
        "original name":"Cat",
-       "unconstrained":0.120218071527276
+       "unconstrained":0.3607268493024173
       },
      "Chimp":{
-       "MG94xREV with separate rates for branch sets":0.001827968855137289,
-       "Nucleotide GTR":0.001817801565830578,
-       "constrained":0.0006181497274348637,
+       "MG94xREV with separate rates for branch sets":0.001828401123834132,
+       "Nucleotide GTR":0.001818373670119325,
+       "constrained":0.001854421055569225,
        "original name":"Chimp",
-       "unconstrained":0.0006183542388399873
+       "unconstrained":0.001853794709397617
       },
      "Cow":{
-       "MG94xREV with separate rates for branch sets":0.2477119781238836,
-       "Nucleotide GTR":0.2480176045457076,
-       "constrained":0.1036665344622347,
+       "MG94xREV with separate rates for branch sets":0.2477981038577003,
+       "Nucleotide GTR":0.2481025999892287,
+       "constrained":0.3115800338446564,
        "original name":"Cow",
-       "unconstrained":0.1088268022245659
+       "unconstrained":0.3266266518611717
       },
      "Horse":{
-       "MG94xREV with separate rates for branch sets":0.211203801568566,
-       "Nucleotide GTR":0.2090856782081004,
-       "constrained":0.08236651201101133,
+       "MG94xREV with separate rates for branch sets":0.21116782461044,
+       "Nucleotide GTR":0.2090310577070883,
+       "constrained":0.2473423214593362,
        "original name":"Horse",
-       "unconstrained":0.08564084427400141
+       "unconstrained":0.2568895651944081
       },
      "Human":{
        "MG94xREV with separate rates for branch sets":0,
@@ -77,68 +77,68 @@
        "unconstrained":0
       },
      "Mouse":{
-       "MG94xREV with separate rates for branch sets":0.1200702443392807,
-       "Nucleotide GTR":0.1181301915748399,
-       "constrained":0.04601717170435755,
+       "MG94xREV with separate rates for branch sets":0.1200804161847832,
+       "Nucleotide GTR":0.1180171198334285,
+       "constrained":0.1381882260320684,
        "original name":"Mouse",
-       "unconstrained":0.04942545223877414
+       "unconstrained":0.1482500840848965
       },
      "Node1":{
-       "MG94xREV with separate rates for branch sets":0.2837967450491412,
-       "Nucleotide GTR":0.2767871391397028,
-       "constrained":0.1295742765519239,
-       "unconstrained":0.1515367890887531
+       "MG94xREV with separate rates for branch sets":0.2841417945012228,
+       "Nucleotide GTR":0.2767237570684924,
+       "constrained":0.3893703941610758,
+       "unconstrained":0.4535373691584812
       },
      "Node12":{
-       "MG94xREV with separate rates for branch sets":0.01788296579298991,
-       "Nucleotide GTR":0.01784443144961206,
-       "constrained":0.005338125135456628,
-       "unconstrained":0.00572208893382143
+       "MG94xREV with separate rates for branch sets":0.01789005959388253,
+       "Nucleotide GTR":0.01784803874223016,
+       "constrained":0.01603697675468384,
+       "unconstrained":0.01716581823757766
       },
      "Node2":{
-       "MG94xREV with separate rates for branch sets":0.06423714540466627,
-       "Nucleotide GTR":0.06616183769400197,
-       "constrained":0.02253286838656328,
-       "unconstrained":0.02248978054488407
+       "MG94xREV with separate rates for branch sets":0.06425321743363792,
+       "Nucleotide GTR":0.06613162123865737,
+       "constrained":0.06766882319669908,
+       "unconstrained":0.06748821329187271
       },
      "Node3":{
-       "MG94xREV with separate rates for branch sets":0.1017201477652066,
-       "Nucleotide GTR":0.09890202668045614,
-       "constrained":0.04280347934583096,
-       "unconstrained":0.04618990784049085
+       "MG94xREV with separate rates for branch sets":0.1017634409613201,
+       "Nucleotide GTR":0.09886326330774685,
+       "constrained":0.128627313187861,
+       "unconstrained":0.1385358286963005
       },
      "Node8":{
-       "MG94xREV with separate rates for branch sets":0.1096720572321177,
-       "Nucleotide GTR":0.10624077635158,
-       "constrained":0.04415239867414091,
-       "unconstrained":0.04768889036449767
+       "MG94xREV with separate rates for branch sets":0.1095532710088725,
+       "Nucleotide GTR":0.106239268140425,
+       "constrained":0.1326559254556453,
+       "unconstrained":0.1430782720540034
       },
      "Node9":{
-       "MG94xREV with separate rates for branch sets":0.02591275475412757,
-       "Nucleotide GTR":0.02566524291670843,
-       "constrained":0.00997308939110993,
-       "unconstrained":0.009841415288506062
+       "MG94xREV with separate rates for branch sets":0.02590764371262369,
+       "Nucleotide GTR":0.02566573875750134,
+       "constrained":0.02991066003065707,
+       "unconstrained":0.02952913741456189
       },
      "Pig":{
-       "MG94xREV with separate rates for branch sets":0.1928073761020463,
-       "Nucleotide GTR":0.1871746592118726,
-       "constrained":0.07816490289585476,
+       "MG94xREV with separate rates for branch sets":0.1925158663261413,
+       "Nucleotide GTR":0.1871893456388788,
+       "constrained":0.2351007649069627,
        "original name":"Pig",
-       "unconstrained":0.08275992348314189
+       "unconstrained":0.248176820169511
       },
      "Rat":{
-       "MG94xREV with separate rates for branch sets":0.06698958986289986,
-       "Nucleotide GTR":0.06656862018951525,
-       "constrained":0.02277034233250765,
+       "MG94xREV with separate rates for branch sets":0.06699144002108472,
+       "Nucleotide GTR":0.06661283005976348,
+       "constrained":0.06832918896283274,
        "original name":"Rat",
-       "unconstrained":0.02372534359054489
+       "unconstrained":0.07114161288708017
       },
      "RhMonkey":{
-       "MG94xREV with separate rates for branch sets":0.003717482368324115,
-       "Nucleotide GTR":0.003775504255522691,
-       "constrained":0.001359450941376631,
+       "MG94xREV with separate rates for branch sets":0.003716234330029482,
+       "Nucleotide GTR":0.003775170135617877,
+       "constrained":0.004078975866589158,
        "original name":"RhMonkey",
-       "unconstrained":0.00132482447204072
+       "unconstrained":0.003977618821878279
       }
     },
    "attributes":{
@@ -174,35 +174,35 @@
   },
  "fits":{
    "Constrained model":{
-     "AIC-c":6918.851822592964,
-     "Log Likelihood":-3419.573452280089,
+     "AIC-c":6918.865252134614,
+     "Log Likelihood":-3419.580167050914,
      "Rate Distributions":{
        "Synonymous site-to-site rates":{
          "0":{
-           "proportion":0.3289898788632067,
-           "rate":0.3124849036133048
+           "proportion":0.3286044813984554,
+           "rate":0.3114745230555425
           },
          "1":{
-           "proportion":0.5748197734913485,
-           "rate":1.039520868895482
+           "proportion":0.5759073485616787,
+           "rate":1.038727366194607
           },
          "2":{
-           "proportion":0.09619034764544485,
-           "rate":3.115265578623139
+           "proportion":0.09548817003986594,
+           "rate":3.135858111155513
           }
         },
        "Test":{
          "0":{
            "omega":0,
-           "proportion":0.02093092071081848
+           "proportion":0.1610337459523823
           },
          "1":{
-           "omega":0,
-           "proportion":0.1387433808480476
+           "omega":0.9239856235614761,
+           "proportion":0
           },
          "2":{
            "omega":1,
-           "proportion":0.8403256984411339
+           "proportion":0.8389662540476177
           }
         }
       },
@@ -210,129 +210,129 @@
      "estimated parameters":39
     },
    "MG94xREV with separate rates for branch sets":{
-     "AIC-c":6997.089050462658,
+     "AIC-c":6997.104847699299,
      "Equilibrium frequencies":      [
-[0.04875339327772683],
-      [0.03982858547830345],
-      [0.04946803524790992],
-      [0.04152216138298744],
-      [0.01811683453600613],
-      [0.01480036248560469],
-      [0.0183823965708893],
-      [0.01542969784826435],
-      [0.01894694796506697],
-      [0.01547851515238824],
-      [0.01922467805342367],
-      [0.01613668666381816],
-      [0.02832099415740372],
-      [0.02313654621336914],
-      [0.02873613184734657],
-      [0.02412034959764736],
-      [0.01662182431200483],
-      [0.01357902918971745],
-      [0.01686547203528639],
-      [0.01415643148428886],
-      [0.006176695005242439],
-      [0.005045987744654046],
-      [0.006267234867003878],
-      [0.005260551308914496],
-      [0.006459711194459957],
-      [0.005277194922783805],
-      [0.006554399593040238],
-      [0.005501589790395056],
-      [0.009655668202293983],
-      [0.007888099278638223],
-      [0.009797203904398108],
-      [0.008223514024394991],
-      [0.03326722643528176],
-      [0.02717732003095303],
-      [0.03375486749252685],
-      [0.02833294365668738],
-      [0.01236215156074466],
-      [0.01009913314808799],
-      [0.01254335971371867],
-      [0.01052856463184265],
-      [0.01292858539344675],
-      [0.0105618754683007],
-      [0.0131180965046964],
-      [0.01101098350431497],
-      [0.0193250328267319],
-      [0.01578738770911659],
-      [0.0196083049972345],
-      [0.01645869298147252],
-      [0.01962343746171723],
-      [0.02045785777700414],
-      [0.008926115885166477],
-      [0.007292098982657142],
-      [0.009056957588961733],
-      [0.007602170831388156],
-      [0.007626222986467745],
-      [0.009471947420992787],
-      [0.007950502328516303],
-      [0.01395367801862353],
-      [0.01139931439306339],
-      [0.01415821524731906],
-      [0.01188403168729233] 
+[0.04876086397632926],
+      [0.03982224127745371],
+      [0.0494959405650269],
+      [0.04152830682371345],
+      [0.01810345074594235],
+      [0.01478480742075003],
+      [0.01837636270304883],
+      [0.01541821854326533],
+      [0.01892910005547028],
+      [0.01545910240515689],
+      [0.01921445878706794],
+      [0.01612140169177368],
+      [0.02829747763884322],
+      [0.02311011106415996],
+      [0.02872406592369408],
+      [0.02410019507229243],
+      [0.01663805943190806],
+      [0.01358804506433061],
+      [0.01688888041768248],
+      [0.01417018446135155],
+      [0.006177213955434187],
+      [0.005044834822351987],
+      [0.006270336287397383],
+      [0.00526096577332031],
+      [0.006458939937330408],
+      [0.005274916061901906],
+      [0.006556309326397028],
+      [0.005500904159606446],
+      [0.009655594186286731],
+      [0.007885574003572761],
+      [0.009801153568494354],
+      [0.008223407979974132],
+      [0.03327785448210915],
+      [0.02717750758119989],
+      [0.03377952261833742],
+      [0.02834184710178207],
+      [0.01235507229404208],
+      [0.01009019590244688],
+      [0.01254132667213156],
+      [0.01052248035033209],
+      [0.01291855364640413],
+      [0.01055038238273567],
+      [0.01311330258173711],
+      [0.01100238215235291],
+      [0.01931219560697892],
+      [0.0157719705998612],
+      [0.01960332955558842],
+      [0.01644767379420349],
+      [0.01965132601881859],
+      [0.02049322866376102],
+      [0.008933621043463411],
+      [0.007295949736387736],
+      [0.009068296583349953],
+      [0.007608523013862737],
+      [0.007628698224327205],
+      [0.009481877006094248],
+      [0.00795552712159237],
+      [0.01396413011303752],
+      [0.01140428846505027],
+      [0.01417464125436193],
+      [0.01189287130232129] 
       ],
-     "Log Likelihood":-3467.004808147542,
+     "Log Likelihood":-3467.012706765863,
      "Rate Distributions":{
        "non-synonymous/synonymous rate ratio for *test*":        [
-[0.9950576192409499, 1] 
+[0.9959842858928788, 1] 
         ]
       },
      "display order":1,
      "estimated parameters":31
     },
    "Nucleotide GTR":{
-     "AIC-c":7112.85745601076,
+     "AIC-c":7112.857310169033,
      "Equilibrium frequencies":      [
 [0.3592490842490842],
       [0.181959706959707],
       [0.240018315018315],
       [0.2187728937728937] 
       ],
-     "Log Likelihood":-3532.321297387654,
+     "Log Likelihood":-3532.32122446679,
      "Rate Distributions":{
-       "Substitution rate from nucleotide A to nucleotide C":0.5497129763145497,
+       "Substitution rate from nucleotide A to nucleotide C":0.5501644800943087,
        "Substitution rate from nucleotide A to nucleotide G":1,
-       "Substitution rate from nucleotide A to nucleotide T":0.264666902964203,
-       "Substitution rate from nucleotide C to nucleotide G":0.4916303643305098,
-       "Substitution rate from nucleotide C to nucleotide T":1.027924764411573,
-       "Substitution rate from nucleotide G to nucleotide T":0.304615404570875
+       "Substitution rate from nucleotide A to nucleotide T":0.2647746107611847,
+       "Substitution rate from nucleotide C to nucleotide G":0.4917423221832032,
+       "Substitution rate from nucleotide C to nucleotide T":1.02837595903795,
+       "Substitution rate from nucleotide G to nucleotide T":0.304509117524575
       },
      "display order":0,
      "estimated parameters":24
     },
    "Unconstrained model":{
-     "AIC-c":6910.766610587704,
-     "Log Likelihood":-3414.486640449675,
+     "AIC-c":6910.776988890891,
+     "Log Likelihood":-3414.491829601268,
      "Rate Distributions":{
        "Synonymous site-to-site rates":{
          "0":{
-           "proportion":0.2645541257391169,
-           "rate":0.2747941124675511
+           "proportion":0.2655037162058198,
+           "rate":0.2749303122566129
           },
          "1":{
-           "proportion":0.6325830460054784,
-           "rate":0.9734675888351726
+           "proportion":0.6321791898264187,
+           "rate":0.9740711294478059
           },
          "2":{
-           "proportion":0.1028628282554047,
-           "rate":3.028333913894314
+           "proportion":0.1023170939677615,
+           "rate":3.041695877803997
           }
         },
        "Test":{
          "0":{
            "omega":0,
-           "proportion":0.04809457608200497
+           "proportion":0.386646389823596
           },
          "1":{
-           "omega":0,
-           "proportion":0.3410012743721951
+           "omega":0.9964438830494696,
+           "proportion":0
           },
          "2":{
-           "omega":1.89363684081788,
-           "proportion":0.6109041495458
+           "omega":1.876622752045829,
+           "proportion":0.613353610176404
           }
         }
       },
@@ -341,7 +341,7 @@
     }
   },
  "input":{
-   "file name":"/tmp/tmp7qHfo2/job_working_directory/000/3/working/./busted_input.fa",
+   "file name":"/tmp/tmpfqvtss8b/job_working_directory/000/3/working/./input.fasta",
    "number of sequences":10,
    "number of sites":187,
    "partition count":1,
@@ -350,8 +350,8 @@
     }
   },
  "test results":{
-   "LRT":10.17362366082671,
-   "p-value":0.003088842014430382
+   "LRT":10.17667489929045,
+   "p-value":0.003084133210483175
   },
  "tested":{
    "0":{
@@ -376,19 +376,19 @@
  "timers":{
    "Constrained BUSTED model fitting":{
      "order":3,
-     "timer":62
+     "timer":70
     },
    "Overall":{
      "order":0,
-     "timer":228
+     "timer":451
     },
    "Preliminary model fitting":{
      "order":1,
-     "timer":3
+     "timer":10
     },
    "Unconstrained BUSTED model fitting":{
      "order":2,
-     "timer":161
+     "timer":370
     }
   }
 }
\ No newline at end of file