diff readme.rst @ 0:fe62ba547975 draft

Uploaded
author iuc
date Wed, 11 Feb 2015 10:18:02 -0500
parents
children
line wrap: on
line diff
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/readme.rst	Wed Feb 11 10:18:02 2015 -0500
@@ -0,0 +1,60 @@
+========================
+Galaxy wrapper for MACS2
+========================
+
+With the improvement of sequencing techniques, chromatin immunoprecipitation 
+followed by high throughput sequencing (ChIP-Seq) is getting popular to study 
+genome-wide protein-DNA interactions. To address the lack of powerful ChIP-Seq 
+analysis method, we present a novel algorithm, named Model-based Analysis of 
+ChIP-Seq (MACS), for identifying transcript factor binding sites. MACS captures 
+the influence of genome complexity to evaluate the significance of enriched ChIP 
+regions, and MACS improves the spatial resolution of binding sites through 
+combining the information of both sequencing tag position and orientation. 
+MACS can be easily used for ChIP-Seq data alone, or with control sample with the increase of specificity.
+
+
+============
+Installation
+============
+
+It is recommended to install this wrapper via the `Galaxy Tool Shed`.
+
+.. _`Galaxy Tool Shed`: http://toolshed.g2.bx.psu.edu/view/modencode-dcc/macs2
+
+
+=======
+History
+=======
+- v2.0.10.1: Initial public release
+- v2.0.10.3: add "broad peaks" options
+
+
+====================
+Detailed description
+====================
+
+View the original MACS2 documentation: https://github.com/taoliu/MACS/blob/master/README.rst
+
+
+===============================
+Wrapper Licence (MIT/BSD style)
+===============================
+
+Permission to use, copy, modify, and distribute this software and its
+documentation with or without modifications and for any purpose and
+without fee is hereby granted, provided that any copyright notices
+appear in all copies and that both those copyright notices and this
+permission notice appear in supporting documentation, and that the
+names of the contributors or copyright holders not be used in
+advertising or publicity pertaining to distribution of the software
+without specific prior permission.
+
+THE CONTRIBUTORS AND COPYRIGHT HOLDERS OF THIS SOFTWARE DISCLAIM ALL
+WARRANTIES WITH REGARD TO THIS SOFTWARE, INCLUDING ALL IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS, IN NO EVENT SHALL THE
+CONTRIBUTORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY SPECIAL, INDIRECT
+OR CONSEQUENTIAL DAMAGES OR ANY DAMAGES WHATSOEVER RESULTING FROM LOSS
+OF USE, DATA OR PROFITS, WHETHER IN AN ACTION OF CONTRACT, NEGLIGENCE
+OR OTHER TORTIOUS ACTION, ARISING OUT OF OR IN CONNECTION WITH THE USE
+OR PERFORMANCE OF THIS SOFTWARE.
+