comparison test-data/pre_cco_core.obo @ 0:54d363d435f0 draft default tip

planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/onto-toolkit commit 9422f839ae354d4c26b02d4494abdeaad518d0e6
author iuc
date Fri, 10 Nov 2017 11:31:25 -0500
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1 format-version: 1.2
2 date: 16:02:2007 16:06
3 default-namespace: CCO
4 autogenerated-by: ONTO-PERL
5 remark: The Cell-Cycle Ontology
6
7 [Term]
8 id: CCO:B0000000
9 name: core cell cycle protein
10 def: "A protein being considered as principal in the regulation of the cell cycle process" [CCO:cco_team]
11 is_a: CCO:U0000005 ! protein
12
13 [Term]
14 id: CCO:P0000001
15 name: mitotic spindle elongation
16 def: "Lengthening of the distance between poles of the mitotic spindle." [GOC:mah]
17 is_a: CCO:P0000310 ! spindle elongation
18 relationship: part_of CCO:P0000058 ! mitotic spindle organization and biogenesis
19 synonym: "spindle elongation during mitosis" EXACT []
20 xref: GO:0000022
21
22 [Term]
23 id: CCO:P0000002
24 name: mitotic sister chromatid segregation
25 def: "The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai]
26 is_a: CCO:P0000308 ! cell cycle process
27 relationship: part_of CCO:P0000069 ! mitosis
28 synonym: "mitotic chromosome segregation" EXACT []
29 synonym: "mitotic sister-chromatid adhesion release" NARROW []
30 xref: GO:0000070
31 xref: GO:0016359
32
33 [Term]
34 id: CCO:P0000003
35 name: M phase specific microtubule process
36 def: "A microtubule-based process that occurs only during M phase of the cell cycle." [GOC:mah]
37 relationship: part_of CCO:P0000038 ! M phase
38 synonym: "M-phase specific microtubule process" EXACT []
39 xref: GO:0000072
40
41 [Term]
42 id: CCO:P0000004
43 name: regulation of progression through cell cycle
44 def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:go_curators]
45 is_a: CCO:P0000294 ! regulation of cell cycle
46 synonym: "cell cycle regulator" RELATED []
47 synonym: "RHEB small monomeric GTPase activity" RELATED []
48 synonym: "tumor suppressor" RELATED []
49 synonym: "control of cell cycle progression" EXACT []
50 synonym: "modulation of cell cycle progression" EXACT []
51 synonym: "regulation of cell cycle progression" EXACT []
52 xref: Reactome:156678
53 xref: Reactome:156699
54 xref: Reactome:156711
55 xref: Reactome:162657
56 xref: Reactome:165167
57 xref: Reactome:167104
58 xref: Reactome:167109
59 xref: Reactome:169311
60 xref: Reactome:171117
61 xref: Reactome:171122
62 xref: Reactome:174455
63 xref: Reactome:177752
64 xref: Reactome:177757
65 xref: GO:0000074
66
67 [Term]
68 id: CCO:P0000005
69 name: cell cycle checkpoint
70 def: "A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage." [GOC:mah, ISBN:0815316194]
71 is_a: CCO:P0000004 ! regulation of progression through cell cycle
72 xref: Reactome:69620
73 xref: GO:0000075
74
75 [Term]
76 id: CCO:P0000006
77 name: DNA replication checkpoint
78 def: "A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome." [GOC:rn, PMID:11728327, PMID:12537518]
79 is_a: CCO:P0000157 ! DNA integrity checkpoint
80 xref: GO:0000076
81
82 [Term]
83 id: CCO:P0000007
84 name: DNA damage checkpoint
85 def: "A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds." [PMID:11891124]
86 is_a: CCO:P0000157 ! DNA integrity checkpoint
87 synonym: "DNA damage response, signal transduction resulting in cell cycle arrest" NARROW []
88 xref: GO:0000077
89
90 [Term]
91 id: CCO:P0000008
92 name: cell morphogenesis checkpoint
93 def: "A cell cycle checkpoint observed when aspects of polarity control are defective, which maintains coordination between the process of cellular morphogenesis and the nuclear events of the cell cycle. For example, in budding yeast cell-cycle delay or arrest is induced when aspects of bud formation are defective." [GOC:vw, PMID:14644188]
94 is_a: CCO:P0000005 ! cell cycle checkpoint
95 xref: GO:0000078
96
97 [Term]
98 id: CCO:P0000009
99 name: regulation of cyclin-dependent protein kinase activity
100 def: "Any process that modulates the frequency, rate or extent of CDK activity." [GOC:go_curators]
101 is_a: CCO:P0000004 ! regulation of progression through cell cycle
102 synonym: "regulation of CDK activity" EXACT []
103 xref: GO:0000079
104
105 [Term]
106 id: CCO:P0000010
107 name: G1 phase of mitotic cell cycle
108 def: "Progression through G1 phase, one of two 'gap' phases in the mitotic cell cycle; G1 is the interval between the completion of mitosis and the beginning of DNA synthesis." [ISBN:0815316194]
109 is_a: CCO:P0000262 ! G1 phase
110 relationship: part_of CCO:P0000273 ! interphase of mitotic cell cycle
111 xref: Reactome:69236
112 xref: GO:0000080
113
114 [Term]
115 id: CCO:P0000011
116 name: G1/S transition of mitotic cell cycle
117 def: "Progression from G1 phase to S phase of the mitotic cell cycle." [GOC:mah]
118 is_a: CCO:P0000308 ! cell cycle process
119 relationship: part_of CCO:P0000273 ! interphase of mitotic cell cycle
120 xref: Reactome:69206
121 xref: GO:0000082
122
123 [Term]
124 id: CCO:P0000012
125 name: G1/S-specific transcription in mitotic cell cycle
126 def: "Any process that regulates transcription such that the target genes are transcribed during the G1/S phase of the mitotic cell cycle." [GOC:mah]
127 is_a: CCO:P0000308 ! cell cycle process
128 relationship: part_of CCO:P0000011 ! G1/S transition of mitotic cell cycle
129 xref: Reactome:69205
130 xref: GO:0000083
131
132 [Term]
133 id: CCO:P0000013
134 name: S phase of mitotic cell cycle
135 def: "Progression through S phase, the part of the mitotic cell cycle during which DNA synthesis takes place." [ISBN:0815316194]
136 is_a: CCO:P0000264 ! S phase
137 relationship: part_of CCO:P0000273 ! interphase of mitotic cell cycle
138 xref: GO:0000084
139
140 [Term]
141 id: CCO:P0000014
142 name: G2 phase of mitotic cell cycle
143 def: "Progression through G2 phase, one of two 'gap' phases in the mitotic cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of mitosis." [ISBN:0815316194]
144 is_a: CCO:P0000263 ! G2 phase
145 relationship: part_of CCO:P0000273 ! interphase of mitotic cell cycle
146 xref: Reactome:68911
147 xref: GO:0000085
148
149 [Term]
150 id: CCO:P0000015
151 name: G2/M transition of mitotic cell cycle
152 def: "Progression from G2 phase to M phase of the mitotic cell cycle." [GOC:mah]
153 is_a: CCO:P0000308 ! cell cycle process
154 relationship: part_of CCO:P0000273 ! interphase of mitotic cell cycle
155 xref: Reactome:69275
156 xref: GO:0000086
157
158 [Term]
159 id: CCO:P0000016
160 name: M phase of mitotic cell cycle
161 def: "Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:mah, ISBN:0815316194]
162 is_a: CCO:P0000038 ! M phase
163 relationship: part_of CCO:P0000037 ! mitotic cell cycle
164 synonym: "M-phase of mitotic cell cycle" EXACT []
165 xref: Reactome:68886
166 xref: GO:0000087
167
168 [Term]
169 id: CCO:P0000017
170 name: mitotic prophase
171 def: "Progression through prophase, the initial stage of mitosis in which the chromosomes are condensed but are not yet attached to a mitotic spindle." [ISBN:0815316194]
172 is_a: CCO:P0000268 ! prophase
173 relationship: part_of CCO:P0000069 ! mitosis
174 xref: Reactome:68875
175 xref: GO:0000088
176
177 [Term]
178 id: CCO:P0000018
179 name: mitotic metaphase
180 def: "Progression through metaphase, the stage of mitosis at which chromosomes are firmly attached to the mitotic spindle at its equator but have not yet segregated to opposite poles." [ISBN:0815316194]
181 is_a: CCO:P0000267 ! metaphase
182 relationship: part_of CCO:P0000069 ! mitosis
183 xref: Reactome:68879
184 xref: GO:0000089
185
186 [Term]
187 id: CCO:P0000019
188 name: mitotic anaphase
189 def: "Progression through anaphase, the stage of mitosis during which the two sets of chromosomes separate and move away from each other." [ISBN:0815316194]
190 is_a: CCO:P0000266 ! anaphase
191 relationship: part_of CCO:P0000069 ! mitosis
192 xref: Reactome:68882
193 xref: GO:0000090
194
195 [Term]
196 id: CCO:P0000020
197 name: mitotic anaphase A
198 def: "Progression through anaphase A, the part of mitotic anaphase in which the kinetochore microtubules shorten as chromosomes move toward the spindle poles." [ISBN:0815316194]
199 is_a: CCO:P0000019 ! mitotic anaphase
200 xref: GO:0000091
201
202 [Term]
203 id: CCO:P0000021
204 name: mitotic anaphase B
205 def: "Progression through anaphase B, the part of mitotic anaphase in which the polar microtubules elongate and the two poles of the spindle move farther apart." [ISBN:0815316194]
206 is_a: CCO:P0000019 ! mitotic anaphase
207 xref: GO:0000092
208
209 [Term]
210 id: CCO:P0000022
211 name: mitotic telophase
212 def: "Progression through telophase, the last of the stages of mitosis; in the canonical cell cycle, telophase begins when the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [ISBN:0721662544]
213 is_a: CCO:P0000270 ! telophase
214 relationship: part_of CCO:P0000069 ! mitosis
215 xref: GO:0000093
216
217 [Term]
218 id: CCO:P0000023
219 name: G1-specific transcription in mitotic cell cycle
220 def: "Any process that regulates transcription such that the target genes are transcribed during the G1 phase of the mitotic cell cycle." [GOC:mah]
221 is_a: CCO:P0000308 ! cell cycle process
222 relationship: part_of CCO:P0000010 ! G1 phase of mitotic cell cycle
223 xref: GO:0000114
224
225 [Term]
226 id: CCO:P0000024
227 name: S-phase-specific transcription in mitotic cell cycle
228 def: "A cell cycle process that regulates transcription such that the target genes are transcribed during the S phase of the mitotic cell cycle." [GOC:mah]
229 is_a: CCO:P0000308 ! cell cycle process
230 relationship: part_of CCO:P0000013 ! S phase of mitotic cell cycle
231 synonym: "S-specific transcription in mitotic cell cycle" EXACT []
232 xref: Reactome:69241
233 xref: GO:0000115
234
235 [Term]
236 id: CCO:P0000025
237 name: G2-specific transcription in mitotic cell cycle
238 def: "Any process that regulates transcription such that the target genes are transcribed during the G2 phase of the mitotic cell cycle." [GOC:mah]
239 is_a: CCO:P0000308 ! cell cycle process
240 relationship: part_of CCO:P0000014 ! G2 phase of mitotic cell cycle
241 xref: GO:0000116
242
243 [Term]
244 id: CCO:P0000026
245 name: G2/M-specific transcription in mitotic cell cycle
246 def: "Any process that regulates transcription such that the target genes are transcribed during the G2/M phase of the mitotic cell cycle." [GOC:mah]
247 is_a: CCO:P0000308 ! cell cycle process
248 relationship: part_of CCO:P0000015 ! G2/M transition of mitotic cell cycle
249 xref: Reactome:69274
250 xref: GO:0000117
251
252 [Term]
253 id: CCO:P0000027
254 name: establishment of mitotic spindle orientation
255 def: "The processes that set the alignment of mitotic spindle relative to other cellular structures." [GOC:ems]
256 is_a: CCO:P0000177 ! establishment of mitotic spindle localization
257 synonym: "establishment of spindle orientation during mitosis" EXACT []
258 synonym: "mitotic spindle orientation" EXACT []
259 synonym: "orienting of mitotic spindle" EXACT []
260 synonym: "mitotic spindle orientation (sensu Fungi)" NARROW []
261 synonym: "mitotic spindle orientation (sensu Saccharomyces)" NARROW []
262 xref: GO:0000132
263 xref: GO:0030607
264 xref: GO:0030609
265
266 [Term]
267 id: CCO:P0000028
268 name: septin checkpoint
269 def: "A cell cycle checkpoint that detects septin defects and responds by inhibiting the mitotic CDK. In Saccharomyces cerevisiae, correct formation of a functional septin cytoskeleton permits the cell to switch to isotropic bud growth and the onset of mitotic chromosome segregation. In the presence of septin defects, the mitotic CDK is inhibited and both the switch to isotropic bud growth and the onset of mitotic chromosome segregation is delayed." [PMID:9925642]
270 is_a: CCO:P0000005 ! cell cycle checkpoint
271 xref: GO:0000135
272
273 [Term]
274 id: CCO:P0000029
275 name: meiotic spindle organization and biogenesis
276 def: "The cell cycle process whereby the microtubule spindle is formed and maintained during a meiotic cell cycle." [GOC:mah]
277 is_a: CCO:P0000308 ! cell cycle process
278 relationship: part_of CCO:P0000265 ! meiotic cell cycle
279 synonym: "meiotic spindle organisation and biogenesis" EXACT []
280 synonym: "spindle organization and biogenesis during meiosis" EXACT []
281 xref: GO:0000212
282
283 [Term]
284 id: CCO:P0000030
285 name: M/G1 transition of mitotic cell cycle
286 def: "Progression from M phase to G1 phase of the mitotic cell cycle." [GOC:mah]
287 is_a: CCO:P0000308 ! cell cycle process
288 relationship: part_of CCO:P0000273 ! interphase of mitotic cell cycle
289 xref: Reactome:68874
290 xref: GO:0000216
291
292 [Term]
293 id: CCO:P0000031
294 name: mitotic prometaphase
295 def: "Progression through prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles." [GOC:mah, ISBN:0198547684]
296 is_a: CCO:P0000309 ! cell cycle phase
297 relationship: part_of CCO:P0000069 ! mitosis
298 xref: Reactome:68877
299 xref: GO:0000236
300
301 [Term]
302 id: CCO:P0000032
303 name: leptotene
304 def: "Progression through the first stage of prophase I in meiosis, in which chromosomes first become visible." [ISBN:0198547684]
305 is_a: CCO:P0000309 ! cell cycle phase
306 relationship: part_of CCO:P0000105 ! meiotic prophase I
307 xref: GO:0000237
308
309 [Term]
310 id: CCO:P0000033
311 name: zygotene
312 def: "Progression through the second stage of prophase I in meiosis, in which each chromosome pairs with its homolog; the two become aligned and crossing over may occur." [ISBN:0198547684]
313 is_a: CCO:P0000309 ! cell cycle phase
314 relationship: part_of CCO:P0000105 ! meiotic prophase I
315 xref: GO:0000238
316
317 [Term]
318 id: CCO:P0000034
319 name: pachytene
320 def: "Progression through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome." [ISBN:0198547684]
321 is_a: CCO:P0000309 ! cell cycle phase
322 relationship: part_of CCO:P0000105 ! meiotic prophase I
323 xref: GO:0000239
324
325 [Term]
326 id: CCO:P0000035
327 name: diplotene
328 def: "Progression through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." [ISBN:0198547684]
329 is_a: CCO:P0000309 ! cell cycle phase
330 relationship: part_of CCO:P0000105 ! meiotic prophase I
331 xref: GO:0000240
332
333 [Term]
334 id: CCO:P0000036
335 name: diakinesis
336 def: "Progression through the final stage of prophase I in meiosis; the transition to meiotic metaphase I." [ISBN:0198547684]
337 is_a: CCO:P0000309 ! cell cycle phase
338 relationship: part_of CCO:P0000105 ! meiotic prophase I
339 xref: GO:0000241
340
341 [Term]
342 id: CCO:P0000037
343 name: mitotic cell cycle
344 def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, in which a cell is duplicated without changing ploidy; comprises four successive phases called G1, S, G2, and M." [GOC:mah, ISBN:0815316194]
345 is_a: CCO:P0000056 ! cell cycle
346 xref: Reactome:69278
347 xref: GO:0000278
348
349 [Term]
350 id: CCO:P0000038
351 name: M phase
352 def: "Progression through M phase, the part of the cell cycle comprising nuclear division and cytokinesis." [ISBN:0815316194]
353 is_a: CCO:P0000309 ! cell cycle phase
354 synonym: "M-phase" EXACT []
355 xref: GO:0000279
356
357 [Term]
358 id: CCO:P0000039
359 name: cytokinesis after mitosis
360 def: "The processes resulting in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells." [GOC:ai]
361 is_a: CCO:P0000308 ! cell cycle process
362 relationship: part_of CCO:P0000016 ! M phase of mitotic cell cycle
363 xref: GO:0000281
364
365 [Term]
366 id: CCO:P0000040
367 name: re-entry into mitotic cell cycle
368 def: "The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state." [GOC:krc]
369 is_a: CCO:P0000004 ! regulation of progression through cell cycle
370 xref: GO:0000320
371
372 [Term]
373 id: CCO:P0000041
374 name: re-entry into mitotic cell cycle after pheromone arrest
375 def: "The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated." [GOC:krc, PMID:9927449]
376 is_a: CCO:P0000040 ! re-entry into mitotic cell cycle
377 synonym: "re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces)" NARROW []
378 xref: GO:0000321
379
380 [Term]
381 id: CCO:P0000042
382 name: achiasmate meiosis I
383 def: "The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata." [GOC:elh, GOC:sart, PMID:10690419]
384 is_a: CCO:P0000104 ! meiosis I
385 xref: GO:0000705
386
387 [Term]
388 id: CCO:P0000043
389 name: meiotic DNA double-strand break processing
390 def: "The cell cycle process whereby the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis." [GOC:elh, PMID:9334324]
391 is_a: CCO:P0000308 ! cell cycle process
392 relationship: part_of CCO:P0000054 ! meiotic gene conversion
393 relationship: part_of CCO:P0000108 ! meiotic recombination
394 xref: GO:0000706
395
396 [Term]
397 id: CCO:P0000044
398 name: meiotic DNA recombinase assembly
399 def: "During meiosis, the assembly of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA." [GOC:elh, PMID:11459983]
400 is_a: CCO:P0000308 ! cell cycle process
401 relationship: part_of CCO:P0000054 ! meiotic gene conversion
402 relationship: part_of CCO:P0000108 ! meiotic recombination
403 xref: GO:0000707
404
405 [Term]
406 id: CCO:P0000045
407 name: meiotic strand invasion
408 def: "The cell cycle process whereby the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis." [GOC:elh, PMID:10915877]
409 is_a: CCO:P0000308 ! cell cycle process
410 relationship: part_of CCO:P0000054 ! meiotic gene conversion
411 relationship: part_of CCO:P0000108 ! meiotic recombination
412 synonym: "meiotic D-loop biosynthesis" RELATED []
413 synonym: "meiotic D-loop formation" RELATED []
414 xref: GO:0000708
415
416 [Term]
417 id: CCO:P0000046
418 name: meiotic joint molecule formation
419 def: "The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule. These joint molecules contain Holliday junctions on either side of heteroduplex DNA." [GOC:elh, PMID:8521495]
420 is_a: CCO:P0000308 ! cell cycle process
421 relationship: part_of CCO:P0000108 ! meiotic recombination
422 xref: GO:0000709
423
424 [Term]
425 id: CCO:P0000047
426 name: meiotic mismatch repair
427 def: "A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis." [GOC:elh, PMID:10357855]
428 is_a: CCO:P0000308 ! cell cycle process
429 relationship: part_of CCO:P0000054 ! meiotic gene conversion
430 relationship: part_of CCO:P0000108 ! meiotic recombination
431 xref: GO:0000710
432
433 [Term]
434 id: CCO:P0000048
435 name: meiotic DNA repair synthesis
436 def: "During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template." [GOC:elh, PMID:9334324]
437 is_a: CCO:P0000308 ! cell cycle process
438 relationship: part_of CCO:P0000054 ! meiotic gene conversion
439 relationship: part_of CCO:P0000108 ! meiotic recombination
440 xref: GO:0000711
441
442 [Term]
443 id: CCO:P0000049
444 name: resolution of meiotic joint molecules as recombinants
445 def: "The cleavage and rejoining of Holliday junctions to produce two intact molecules in which genetic material has been exchanged." [GOC:elh, PMID:11733053]
446 is_a: CCO:P0000254 ! meiotic chromosome separation
447 relationship: part_of CCO:P0000108 ! meiotic recombination
448 relationship: part_of CCO:P0000191 ! homologous chromosome segregation
449 synonym: "meiotic homologous chromosome separation" RELATED []
450 synonym: "homologous chromosome separation at meiosis I" EXACT []
451 synonym: "crossover biosynthesis" NARROW []
452 synonym: "crossover formation" NARROW []
453 synonym: "formation of chiasmata" NARROW []
454 xref: GO:0000712
455
456 [Term]
457 id: CCO:P0000050
458 name: meiotic heteroduplex formation
459 def: "During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules." [GOC:elh, PMID:9334324]
460 is_a: CCO:P0000308 ! cell cycle process
461 relationship: part_of CCO:P0000054 ! meiotic gene conversion
462 xref: GO:0000713
463
464 [Term]
465 id: CCO:P0000051
466 name: meiotic strand displacement
467 def: "The cell cycle process whereby the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis." [GOC:elh, PMID:10357855]
468 is_a: CCO:P0000308 ! cell cycle process
469 relationship: part_of CCO:P0000054 ! meiotic gene conversion
470 xref: GO:0000714
471
472 [Term]
473 id: CCO:P0000052
474 name: cell cycle arrest in response to pheromone
475 def: "The processes that lead to a halt in cell cycle progression (cessation of cell cycle transitions) as a result of a pheromone stimulus." [GOC:clt]
476 is_a: CCO:P0000057 ! cell cycle arrest
477 synonym: "cell cycle arrest (sensu Saccharomyces)" RELATED []
478 xref: GO:0000751
479 xref: GO:0030571
480
481 [Term]
482 id: CCO:P0000053
483 name: negative regulation of exit from mitosis
484 def: "Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)." [GOC:rn]
485 is_a: CCO:P0000095 ! regulation of exit from mitosis
486 synonym: "down regulation of exit from mitosis" EXACT []
487 synonym: "down-regulation of exit from mitosis" EXACT []
488 synonym: "downregulation of exit from mitosis" EXACT []
489 synonym: "inhibition of exit from mitosis" NARROW []
490 xref: GO:0001100
491
492 [Term]
493 id: CCO:P0000054
494 name: meiotic gene conversion
495 def: "The cell cycle process whereby genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele." [ISBN:0815316194]
496 is_a: CCO:P0000308 ! cell cycle process
497 relationship: part_of CCO:P0000104 ! meiosis I
498 synonym: "gene conversion without reciprocal crossover" EXACT []
499 xref: GO:0006311
500
501 [Term]
502 id: CCO:P0000055
503 name: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
504 def: "A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle." [GOC:go_curators]
505 is_a: CCO:P0000158 ! G1 DNA damage checkpoint
506 xref: GO:0006977
507
508 [Term]
509 id: CCO:P0000056
510 name: cell cycle
511 def: "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." [GOC:go_curators]
512 is_a: CCO:U0000002 ! cell-cycle process
513 synonym: "cell-division cycle" EXACT []
514 xref: GO:0007049
515
516 [Term]
517 id: CCO:P0000057
518 name: cell cycle arrest
519 def: "Any process by which progression through the cell cycle is halted during one of the normal phases (G1, S, G2, M)." [GOC:mah]
520 is_a: CCO:P0000198 ! negative regulation of progression through cell cycle
521 synonym: "arrest of cell cycle progression" EXACT []
522 synonym: "cessation of cell cycle" EXACT []
523 synonym: "termination of cell cycle" EXACT []
524 xref: GO:0007050
525
526 [Term]
527 id: CCO:P0000058
528 name: mitotic spindle organization and biogenesis
529 def: "The cell cycle process whereby the microtubule spindle is formed and maintained during a mitotic cell cycle." [GOC:mah]
530 is_a: CCO:P0000308 ! cell cycle process
531 relationship: part_of CCO:P0000037 ! mitotic cell cycle
532 synonym: "mitotic spindle organisation and biogenesis" EXACT []
533 synonym: "spindle organization and biogenesis during mitosis" EXACT []
534 xref: GO:0007052
535
536 [Term]
537 id: CCO:P0000059
538 name: male meiotic spindle assembly (sensu Metazoa)
539 def: "The formation of the spindle during a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
540 is_a: CCO:P0000242 ! meiotic spindle assembly
541 relationship: part_of CCO:P0000117 ! male meiosis
542 xref: GO:0007053
543
544 [Term]
545 id: CCO:P0000060
546 name: male meiosis I spindle assembly (sensu Metazoa)
547 def: "The formation of the spindle during meiosis I of a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
548 is_a: CCO:P0000059 ! male meiotic spindle assembly (sensu Metazoa)
549 relationship: part_of CCO:P0000118 ! male meiosis I
550 xref: GO:0007054
551
552 [Term]
553 id: CCO:P0000061
554 name: male meiosis II spindle assembly (sensu Metazoa)
555 def: "The formation of the spindle during meiosis I of a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
556 is_a: CCO:P0000059 ! male meiotic spindle assembly (sensu Metazoa)
557 relationship: part_of CCO:P0000119 ! male meiosis II
558 xref: GO:0007055
559
560 [Term]
561 id: CCO:P0000062
562 name: female meiotic spindle assembly (sensu Metazoa)
563 def: "The formation of the spindle during a meiotic cell cycle in females. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
564 is_a: CCO:P0000242 ! meiotic spindle assembly
565 relationship: part_of CCO:P0000120 ! female meiosis
566 xref: GO:0007056
567
568 [Term]
569 id: CCO:P0000063
570 name: female meiosis I spindle assembly (sensu Metazoa)
571 def: "The formation of the spindle during meiosis I of a meiotic cell cycle in females. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
572 is_a: CCO:P0000062 ! female meiotic spindle assembly (sensu Metazoa)
573 relationship: part_of CCO:P0000121 ! female meiosis I
574 xref: GO:0007057
575
576 [Term]
577 id: CCO:P0000064
578 name: female meiosis II spindle assembly (sensu Metazoa)
579 def: "The formation of the spindle during meiosis II of a meiotic cell cycle in females. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah]
580 is_a: CCO:P0000062 ! female meiotic spindle assembly (sensu Metazoa)
581 relationship: part_of CCO:P0000123 ! female meiosis II
582 xref: GO:0007058
583
584 [Term]
585 id: CCO:P0000065
586 name: male meiosis chromosome segregation
587 def: "The cell cycle process whereby genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male." [GOC:ai]
588 is_a: CCO:P0000189 ! meiotic chromosome segregation
589 is_a: CCO:P0000308 ! cell cycle process
590 relationship: part_of CCO:P0000117 ! male meiosis
591 xref: GO:0007060
592
593 [Term]
594 id: CCO:P0000066
595 name: mitotic sister chromatid cohesion
596 def: "The cell cycle process whereby the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during mitosis. This cohesion cycle is critical for high fidelity chromosome transmission." [GOC:ai, GOC:rn, PMID:10827941, PMID:11389843]
597 is_a: CCO:P0000308 ! cell cycle process
598 relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation
599 synonym: "mitotic sister-chromatid adhesion release" RELATED []
600 xref: GO:0007064
601
602 [Term]
603 id: CCO:P0000067
604 name: male meiosis sister chromatid cohesion
605 def: "The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male." [GOC:ai]
606 is_a: CCO:P0000240 ! meiotic sister chromatid cohesion
607 relationship: part_of CCO:P0000117 ! male meiosis
608 xref: GO:0007065
609
610 [Term]
611 id: CCO:P0000068
612 name: female meiosis sister chromatid cohesion
613 def: "The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female." [GOC:ai]
614 is_a: CCO:P0000240 ! meiotic sister chromatid cohesion
615 relationship: part_of CCO:P0000120 ! female meiosis
616 xref: GO:0007066
617
618 [Term]
619 id: CCO:P0000069
620 name: mitosis
621 def: "Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:ma, ISBN:0198547684]
622 is_a: CCO:P0000309 ! cell cycle phase
623 relationship: part_of CCO:P0000016 ! M phase of mitotic cell cycle
624 xref: GO:0007067
625
626 [Term]
627 id: CCO:P0000070
628 name: negative regulation of transcription, mitotic
629 def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription during mitosis." [GOC:go_curators]
630 is_a: CCO:P0000206 ! regulation of transcription, mitotic
631 synonym: "down regulation of transcription, mitotic" EXACT []
632 synonym: "down-regulation of transcription, mitotic" EXACT []
633 synonym: "downregulation of transcription, mitotic" EXACT []
634 synonym: "mitotic repression of transcription" EXACT []
635 synonym: "inhibition of transcription, mitotic" NARROW []
636 xref: GO:0007068
637
638 [Term]
639 id: CCO:P0000071
640 name: negative regulation of transcription from RNA polymerase I promoter, mitotic
641 def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter during mitosis." [GOC:go_curators]
642 is_a: CCO:P0000070 ! negative regulation of transcription, mitotic
643 is_a: CCO:P0000216 ! regulation of transcription from RNA polymerase I promoter, mitotic
644 synonym: "down regulation of transcription from RNA polymerase I promoter, mitotic" EXACT []
645 synonym: "down-regulation of transcription from RNA polymerase I promoter, mitotic" EXACT []
646 synonym: "downregulation of transcription from RNA polymerase I promoter, mitotic" EXACT []
647 synonym: "mitotic repression of transcription from Pol I promoter" EXACT []
648 synonym: "negative regulation of transcription from Pol I promoter, mitotic" EXACT []
649 synonym: "inhibition of transcription from RNA polymerase I promoter, mitotic" NARROW []
650 xref: GO:0007069
651
652 [Term]
653 id: CCO:P0000072
654 name: negative regulation of transcription from RNA polymerase II promoter, mitotic
655 def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter during mitosis." [GOC:go_curators]
656 is_a: CCO:P0000070 ! negative regulation of transcription, mitotic
657 is_a: CCO:P0000218 ! regulation of transcription from RNA polymerase II promoter, mitotic
658 synonym: "down regulation of transcription from RNA polymerase II promoter, mitotic" EXACT []
659 synonym: "down-regulation of transcription from RNA polymerase II promoter, mitotic" EXACT []
660 synonym: "downregulation of transcription from RNA polymerase II promoter, mitotic" EXACT []
661 synonym: "mitotic repression of transcription from Pol II promoter" EXACT []
662 synonym: "negative regulation of transcription from Pol II promoter, mitotic" EXACT []
663 synonym: "inhibition of transcription from RNA polymerase II promoter, mitotic" NARROW []
664 xref: GO:0007070
665
666 [Term]
667 id: CCO:P0000073
668 name: negative regulation of transcription from RNA polymerase III promoter, mitotic
669 def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter during mitosis." [GOC:go_curators]
670 is_a: CCO:P0000070 ! negative regulation of transcription, mitotic
671 is_a: CCO:P0000220 ! regulation of transcription from RNA polymerase III promoter, mitotic
672 synonym: "down regulation of transcription from RNA polymerase III promoter, mitotic" EXACT []
673 synonym: "down-regulation of transcription from RNA polymerase III promoter, mitotic" EXACT []
674 synonym: "downregulation of transcription from RNA polymerase III promoter, mitotic" EXACT []
675 synonym: "mitotic repression of transcription from Pol III promoter" EXACT []
676 synonym: "negative regulation of transcription from Pol III promoter, mitotic" EXACT []
677 synonym: "inhibition of transcription from RNA polymerase III promoter, mitotic" NARROW []
678 xref: GO:0007071
679
680 [Term]
681 id: CCO:P0000074
682 name: activation of transcription on exit from mitosis
683 def: "The cell cycle process whereby transcription is positively regulated as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:isa_complete]
684 is_a: CCO:P0000308 ! cell cycle process
685 relationship: part_of CCO:P0000016 ! M phase of mitotic cell cycle
686 xref: GO:0007072
687
688 [Term]
689 id: CCO:P0000075
690 name: activation of transcription on exit from mitosis, from RNA polymerase I promoter
691 is_a: CCO:P0000074 ! activation of transcription on exit from mitosis
692 synonym: "activation of transcription on exit from mitosis, from Pol I promoter" EXACT []
693 xref: GO:0007073
694
695 [Term]
696 id: CCO:P0000076
697 name: activation of transcription on exit from mitosis, from RNA polymerase II promoter
698 is_a: CCO:P0000074 ! activation of transcription on exit from mitosis
699 synonym: "activation of transcription on exit from mitosis, from Pol II promoter" EXACT []
700 xref: GO:0007074
701
702 [Term]
703 id: CCO:P0000077
704 name: activation of transcription on exit from mitosis, from RNA polymerase III promoter
705 is_a: CCO:P0000074 ! activation of transcription on exit from mitosis
706 synonym: "activation of transcription on exit from mitosis, from Pol III promoter" EXACT []
707 xref: GO:0007075
708
709 [Term]
710 id: CCO:P0000078
711 name: mitotic chromosome condensation
712 def: "The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells." [GOC:mah, ISBN:0815316194]
713 is_a: CCO:P0000308 ! cell cycle process
714 relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation
715 xref: GO:0007076
716
717 [Term]
718 id: CCO:P0000079
719 name: mitotic nuclear envelope disassembly
720 def: "The cell cycle process whereby the controlled breakdown of the nuclear envelope during mitotic cell division occurs." [GOC:bf]
721 is_a: CCO:P0000308 ! cell cycle process
722 relationship: part_of CCO:P0000037 ! mitotic cell cycle
723 synonym: "mitotic nuclear envelope breakdown" EXACT []
724 synonym: "mitotic nuclear envelope catabolism" EXACT []
725 synonym: "mitotic nuclear envelope degradation" EXACT []
726 xref: GO:0007077
727
728 [Term]
729 id: CCO:P0000080
730 name: lamin depolymerization
731 def: "The cell cycle process whereby lamin is depolymerized." [GOC:jic]
732 is_a: CCO:P0000308 ! cell cycle process
733 relationship: part_of CCO:P0000079 ! mitotic nuclear envelope disassembly
734 xref: GO:0007078
735
736 [Term]
737 id: CCO:P0000081
738 name: mitotic chromosome movement towards spindle pole
739 def: "The cell cycle process whereby the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis." [GOC:ai]
740 is_a: CCO:P0000308 ! cell cycle process
741 relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation
742 synonym: "chromosome migration to spindle pole during mitosis" EXACT []
743 synonym: "chromosome movement towards spindle pole during mitosis" EXACT []
744 synonym: "mitotic chromosome movement to spindle pole" EXACT []
745 synonym: "mitotic sister chromosome movement towards spindle pole" EXACT []
746 synonym: "sister chromosome movement towards spindle pole during mitosis" EXACT []
747 synonym: "mitotic chromosome movement" BROAD []
748 xref: GO:0007079
749 xref: GO:0007082
750
751 [Term]
752 id: CCO:P0000082
753 name: mitotic metaphase plate congression
754 def: "The cell cycle process whereby chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis." [GOC:mah, ISBN:0815316194]
755 is_a: CCO:P0000308 ! cell cycle process
756 relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation
757 xref: GO:0007080
758
759 [Term]
760 id: CCO:P0000083
761 name: mitotic chromosome decondensation
762 def: "The cell cycle process whereby chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells." [GOC:ai]
763 is_a: CCO:P0000308 ! cell cycle process
764 relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation
765 xref: GO:0007083
766
767 [Term]
768 id: CCO:P0000084
769 name: mitotic nuclear envelope reassembly
770 def: "The cell cycle process whereby the nuclear envelope reforms during mitotic cell division." [GOC:ai]
771 is_a: CCO:P0000308 ! cell cycle process
772 relationship: part_of CCO:P0000037 ! mitotic cell cycle
773 xref: GO:0007084
774
775 [Term]
776 id: CCO:P0000085
777 name: vesicle fusion with nuclear membrane
778 def: "The cell cycle process whereby the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus occurs." [GOC:jic]
779 is_a: CCO:P0000308 ! cell cycle process
780 relationship: part_of CCO:P0000084 ! mitotic nuclear envelope reassembly
781 synonym: "vesicle fusion" BROAD []
782 xref: GO:0007086
783
784 [Term]
785 id: CCO:P0000086
786 name: mitotic nuclear pore complex reassembly
787 def: "The cell cycle process whereby nuclear pore complexes reform during mitotic cell division." [GOC:ai]
788 is_a: CCO:P0000308 ! cell cycle process
789 relationship: part_of CCO:P0000084 ! mitotic nuclear envelope reassembly
790 xref: GO:0007087
791
792 [Term]
793 id: CCO:P0000087
794 name: regulation of mitosis
795 def: "Any process that modulates the frequency, rate or extent of mitosis." [GOC:go_curators]
796 is_a: CCO:P0000004 ! regulation of progression through cell cycle
797 relationship: part_of CCO:P0000069 ! mitosis
798 xref: Reactome:73674
799 xref: GO:0007088
800
801 [Term]
802 id: CCO:P0000088
803 name: traversing start control point of mitotic cell cycle
804 def: "Passage through a cell cycle control point late in G1 phase of the mitotic cell cycle just before entry into S phase; in most organisms studied, including budding yeast and animal cells, passage through start normally commits the cell to progressing through the entire cell cycle." [GOC:mah, ISBN:0815316194]
805 is_a: CCO:P0000124 ! regulation of progression through mitotic cell cycle
806 relationship: part_of CCO:P0000010 ! G1 phase of mitotic cell cycle
807 synonym: "G1 checkpoint" RELATED []
808 xref: GO:0007089
809 xref: GO:0000081
810
811 [Term]
812 id: CCO:P0000089
813 name: regulation of S phase of mitotic cell cycle
814 def: "A cell cycle process that modulates the frequency, rate or extent of the progression through the S phase of mitotic cell cycle." [GOC:go_curators]
815 is_a: CCO:P0000308 ! cell cycle process
816 relationship: part_of CCO:P0000013 ! S phase of mitotic cell cycle
817 relationship: part_of CCO:P0000124 ! regulation of progression through mitotic cell cycle
818 xref: GO:0007090
819
820 [Term]
821 id: CCO:P0000090
822 name: mitotic metaphase/anaphase transition
823 def: "The cell cycle process whereby a cell progresses from metaphase to anaphase during mitosis, triggered by the destruction of mitotic cyclins." [PMID:10465783]
824 is_a: CCO:P0000308 ! cell cycle process
825 relationship: part_of CCO:P0000069 ! mitosis
826 xref: Reactome:68881
827 xref: GO:0007091
828
829 [Term]
830 id: CCO:P0000091
831 name: anaphase-promoting complex activation during mitotic cell cycle
832 def: "Any process that activates, maintains or increases the rate of the ubiquitin ligase activity of the anaphase-promoting complex during the mitotic cell cycle." [GOC:mah, PMID:10871297]
833 is_a: CCO:P0000282 ! positive regulation of ubiquitin ligase activity during mitotic cell cycle
834 relationship: part_of CCO:P0000139 ! regulation of mitotic metaphase/anaphase transition
835 synonym: "activation of ubiquitin ligase activity of anaphase promoting complex during mitotic cell cycle" EXACT []
836 synonym: "activation of ubiquitin ligase activity of anaphase-promoting complex during mitotic cell cycle" EXACT []
837 synonym: "activation of ubiquitin ligase activity of APC during mitotic cell cycle" EXACT []
838 synonym: "anaphase promoting complex activation during mitotic cell cycle" EXACT []
839 synonym: "APC activation during mitotic cell cycle" EXACT []
840 synonym: "mitotic anaphase promoting complex activation" EXACT []
841 synonym: "mitotic anaphase-promoting complex activation" EXACT []
842 synonym: "mitotic APC activation" EXACT []
843 synonym: "mitotic anaphase promoting complex activator" NARROW []
844 synonym: "mitotic anaphase-promoting complex activator" NARROW []
845 synonym: "mitotic APC activator" NARROW []
846 xref: Reactome:162659
847 xref: Reactome:163010
848 xref: Reactome:165237
849 xref: Reactome:166428
850 xref: Reactome:169381
851 xref: Reactome:170447
852 xref: Reactome:173214
853 xref: Reactome:173955
854 xref: Reactome:176216
855 xref: Reactome:177163
856 xref: GO:0007092
857
858 [Term]
859 id: CCO:P0000092
860 name: mitotic checkpoint
861 def: "A signal transduction-based surveillance mechanism that ensures accurate chromosome segregation by preventing entry into, passage through and exit from mitosis. Events that may be monitored include the formation of a correctly assembled spindle, the position of the spindle pole (centrosome) and the orientation of the spindle and cellular morphogenesis." [GOC:rn, PMID:12360190]
862 is_a: CCO:P0000005 ! cell cycle checkpoint
863 is_a: CCO:P0000087 ! regulation of mitosis
864 xref: Reactome:73676
865 xref: GO:0007093
866
867 [Term]
868 id: CCO:P0000093
869 name: mitotic spindle checkpoint
870 def: "A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly)." [GOC:rn, PMID:12360190]
871 is_a: CCO:P0000092 ! mitotic checkpoint
872 is_a: CCO:P0000164 ! spindle checkpoint
873 synonym: "Mad2-dependent checkpoint" NARROW []
874 xref: Reactome:69618
875 xref: GO:0007094
876
877 [Term]
878 id: CCO:P0000094
879 name: mitotic G2 checkpoint
880 def: "A signal transduction-based surveillance mechanism that ensures accurate chromosome segregation by preventing entry into mitosis in the presence of damaged DNA." [GOC:mah, PMID:10856933, PMID:11406266]
881 is_a: CCO:P0000092 ! mitotic checkpoint
882 is_a: CCO:P0000159 ! G2/M transition DNA damage checkpoint
883 synonym: "mitotic G2/M transition DNA damage checkpoint" EXACT []
884 xref: GO:0007095
885
886 [Term]
887 id: CCO:P0000095
888 name: regulation of exit from mitosis
889 def: "Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity." [GOC:rn]
890 is_a: CCO:P0000087 ! regulation of mitosis
891 xref: GO:0007096
892
893 [Term]
894 id: CCO:P0000096
895 name: centrosome cycle
896 def: "The cell cycle process whereby centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle." [ISBN:0815316194]
897 is_a: CCO:P0000308 ! cell cycle process
898 xref: GO:0007098
899
900 [Term]
901 id: CCO:P0000097
902 name: centriole replication
903 def: "The cell cycle process whereby a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type." [GOC:kva, ISBN:0815316194]
904 is_a: CCO:P0000308 ! cell cycle process
905 relationship: part_of CCO:P0000251 ! centrosome duplication
906 synonym: "centriole duplication" EXACT []
907 xref: GO:0007099
908
909 [Term]
910 id: CCO:P0000098
911 name: mitotic centrosome separation
912 def: "Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle." [ISBN:0815316194]
913 is_a: CCO:P0000252 ! centrosome separation
914 xref: GO:0007100
915
916 [Term]
917 id: CCO:P0000099
918 name: male meiosis centrosome cycle
919 def: "Centrosome duplication and separation in the context of male meiosis." [GOC:mah]
920 is_a: CCO:P0000096 ! centrosome cycle
921 xref: GO:0007101
922
923 [Term]
924 id: CCO:P0000100
925 name: cytokinesis after meiosis I
926 def: "The processes resulting in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells." [GOC:ai]
927 is_a: CCO:P0000179 ! polar body extrusion after meiotic divisions
928 xref: GO:0007110
929
930 [Term]
931 id: CCO:P0000101
932 name: cytokinesis after meiosis II
933 def: "The processes resulting in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells." [GOC:ai]
934 is_a: CCO:P0000179 ! polar body extrusion after meiotic divisions
935 xref: GO:0007111
936
937 [Term]
938 id: CCO:P0000102
939 name: endomitotic cell cycle
940 def: "The replication and division of chromosomes which is not followed by nuclear division, resulting in an increased number of chromosomes in the cell." [http:www.onelook.com]
941 is_a: CCO:P0000056 ! cell cycle
942 synonym: "endomitosis" EXACT []
943 xref: GO:0007113
944
945 [Term]
946 id: CCO:P0000103
947 name: meiosis
948 def: "Progression through meiosis, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiosis occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations." [PMID:9334324]
949 is_a: CCO:P0000309 ! cell cycle phase
950 relationship: part_of CCO:P0000271 ! M phase of meiotic cell cycle
951 xref: GO:0007126
952
953 [Term]
954 id: CCO:P0000104
955 name: meiosis I
956 def: "Progression through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." [PMID:9334324]
957 is_a: CCO:P0000309 ! cell cycle phase
958 relationship: part_of CCO:P0000103 ! meiosis
959 xref: GO:0007127
960
961 [Term]
962 id: CCO:P0000105
963 name: meiotic prophase I
964 def: "Progression through prophase of meiosis I; divided into several stages." [GOC:mah]
965 is_a: CCO:P0000268 ! prophase
966 relationship: part_of CCO:P0000104 ! meiosis I
967 xref: GO:0007128
968
969 [Term]
970 id: CCO:P0000106
971 name: synapsis
972 def: "The cell cycle process whereby the side by side pairing and physical juxtaposition of homologous chromosomes is created at the metaphase plate." [GOC:elh]
973 is_a: CCO:P0000308 ! cell cycle process
974 relationship: part_of CCO:P0000104 ! meiosis I
975 synonym: "homologous chromosome pairing at meiosis" EXACT []
976 xref: GO:0007129
977
978 [Term]
979 id: CCO:P0000107
980 name: synaptonemal complex assembly
981 def: "The cell cycle process whereby the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination." [ISBN:0198506732]
982 is_a: CCO:P0000308 ! cell cycle process
983 relationship: part_of CCO:P0000106 ! synapsis
984 synonym: "synaptonemal complex formation" EXACT []
985 xref: GO:0007130
986
987 [Term]
988 id: CCO:P0000108
989 name: meiotic recombination
990 def: "The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity." [PMID:2087779]
991 is_a: CCO:P0000308 ! cell cycle process
992 relationship: part_of CCO:P0000104 ! meiosis I
993 synonym: "gene conversion with reciprocal crossover" EXACT []
994 synonym: "female meiotic recombination" NARROW []
995 xref: GO:0007131
996 xref: GO:0000021
997 xref: GO:0007145
998
999 [Term]
1000 id: CCO:P0000109
1001 name: meiotic metaphase I
1002 def: "Progression through metaphase of meiosis I; analogous to mitotic metaphase." [GOC:mah]
1003 is_a: CCO:P0000267 ! metaphase
1004 relationship: part_of CCO:P0000104 ! meiosis I
1005 xref: GO:0007132
1006
1007 [Term]
1008 id: CCO:P0000110
1009 name: meiotic anaphase I
1010 def: "Progression through anaphase of meiosis I; analogous to mitotic anaphase." [GOC:mah]
1011 is_a: CCO:P0000266 ! anaphase
1012 relationship: part_of CCO:P0000104 ! meiosis I
1013 xref: GO:0007133
1014
1015 [Term]
1016 id: CCO:P0000111
1017 name: meiotic telophase I
1018 def: "Progression through telophase of meiosis I; analogous to mitotic telophase." [GOC:mah]
1019 is_a: CCO:P0000270 ! telophase
1020 relationship: part_of CCO:P0000104 ! meiosis I
1021 xref: GO:0007134
1022
1023 [Term]
1024 id: CCO:P0000112
1025 name: meiosis II
1026 def: "Progression through the second phase of meiosis, in which cells divide and separate the two chromatids in each chromosome." [ISBN:0198547684]
1027 is_a: CCO:P0000309 ! cell cycle phase
1028 relationship: part_of CCO:P0000103 ! meiosis
1029 xref: GO:0007135
1030
1031 [Term]
1032 id: CCO:P0000113
1033 name: meiotic prophase II
1034 def: "Progression through prophase of meiosis II; analogous to mitotic prophase." [GOC:mah]
1035 is_a: CCO:P0000268 ! prophase
1036 relationship: part_of CCO:P0000112 ! meiosis II
1037 xref: GO:0007136
1038
1039 [Term]
1040 id: CCO:P0000114
1041 name: meiotic metaphase II
1042 def: "Progression through metaphase of meiosis II; analogous to mitotic metaphase." [GOC:mah]
1043 is_a: CCO:P0000267 ! metaphase
1044 relationship: part_of CCO:P0000112 ! meiosis II
1045 xref: GO:0007137
1046
1047 [Term]
1048 id: CCO:P0000115
1049 name: meiotic anaphase II
1050 def: "Progression through anaphase of meiosis II; analogous to mitotic anaphase." [GOC:mah]
1051 is_a: CCO:P0000266 ! anaphase
1052 relationship: part_of CCO:P0000112 ! meiosis II
1053 xref: GO:0007138
1054
1055 [Term]
1056 id: CCO:P0000116
1057 name: meiotic telophase II
1058 def: "Progression through telophase of meiosis II; analogous to mitotic telophase." [GOC:mah]
1059 is_a: CCO:P0000270 ! telophase
1060 relationship: part_of CCO:P0000112 ! meiosis II
1061 xref: GO:0007139
1062
1063 [Term]
1064 id: CCO:P0000117
1065 name: male meiosis
1066 def: "Meiosis in the male germline." [GOC:mah]
1067 is_a: CCO:P0000103 ! meiosis
1068 xref: GO:0007140
1069
1070 [Term]
1071 id: CCO:P0000118
1072 name: male meiosis I
1073 def: "Progression through male meiosis I, the first meiotic division in the male germline." [GOC:mah]
1074 is_a: CCO:P0000309 ! cell cycle phase
1075 relationship: part_of CCO:P0000117 ! male meiosis
1076 xref: GO:0007141
1077
1078 [Term]
1079 id: CCO:P0000119
1080 name: male meiosis II
1081 def: "Progression through male meiosis II, the second meiotic division in the male germline." [GOC:mah]
1082 is_a: CCO:P0000309 ! cell cycle phase
1083 relationship: part_of CCO:P0000117 ! male meiosis
1084 xref: GO:0007142
1085
1086 [Term]
1087 id: CCO:P0000120
1088 name: female meiosis
1089 def: "Meiosis in the female germline." [GOC:ems]
1090 is_a: CCO:P0000103 ! meiosis
1091 comment: Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaprodites such as those of C. elegans. See also the biological process term 'meiosis ; GO:0007126'.
1092 xref: GO:0007143
1093
1094 [Term]
1095 id: CCO:P0000121
1096 name: female meiosis I
1097 def: "The cell cycle process whereby the first meiotic division occurs in the female germline." [GOC:mah]
1098 is_a: CCO:P0000308 ! cell cycle process
1099 relationship: part_of CCO:P0000120 ! female meiosis
1100 xref: GO:0007144
1101
1102 [Term]
1103 id: CCO:P0000122
1104 name: meiotic recombination nodule assembly
1105 def: "The assembly of small, electron dense structures in association with meiotic chromosomes." [GOC:jl, PMID:9334324]
1106 is_a: CCO:P0000044 ! meiotic DNA recombinase assembly
1107 xref: GO:0007146
1108
1109 [Term]
1110 id: CCO:P0000123
1111 name: female meiosis II
1112 def: "The cell cycle process whereby the second meiotic division occurs in the female germline." [GOC:mah]
1113 is_a: CCO:P0000308 ! cell cycle process
1114 relationship: part_of CCO:P0000120 ! female meiosis
1115 xref: GO:0007147
1116
1117 [Term]
1118 id: CCO:P0000124
1119 name: regulation of progression through mitotic cell cycle
1120 def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:go_curators]
1121 is_a: CCO:P0000004 ! regulation of progression through cell cycle
1122 relationship: part_of CCO:P0000037 ! mitotic cell cycle
1123 synonym: "mitotic cell cycle regulator" RELATED []
1124 synonym: "control of mitotic cell cycle progression" EXACT []
1125 synonym: "mitotic cell cycle control" EXACT []
1126 synonym: "mitotic cell cycle modulation" EXACT []
1127 synonym: "mitotic cell cycle regulation" EXACT []
1128 synonym: "modulation of mitotic cell cycle progression" EXACT []
1129 synonym: "regulation of mitotic cell cycle" EXACT []
1130 synonym: "regulation of mitotic cell cycle progression" EXACT []
1131 xref: GO:0007346
1132
1133 [Term]
1134 id: CCO:P0000125
1135 name: regulation of progression through preblastoderm mitotic cell cycle
1136 def: "A cell cycle process that modulates the frequency, rate or extent of the progression through the preblastoderm mitotic cell cycle." [GOC:go_curators]
1137 is_a: CCO:P0000308 ! cell cycle process
1138 relationship: part_of CCO:P0000129 ! regulation of progression through embryonic mitotic cell cycle
1139 relationship: part_of CCO:P0000175 ! preblastoderm mitotic cell cycle
1140 synonym: "preblastoderm mitotic cell cycle regulator" RELATED []
1141 synonym: "control of preblastoderm mitotic cell cycle progression" EXACT []
1142 synonym: "modulation of preblastoderm mitotic cell cycle progression" EXACT []
1143 synonym: "preblastoderm mitotic cell cycle control" EXACT []
1144 synonym: "preblastoderm mitotic cell cycle modulation" EXACT []
1145 synonym: "preblastoderm mitotic cell cycle regulation" EXACT []
1146 synonym: "regulation of preblastoderm mitotic cell cycle" EXACT []
1147 synonym: "regulation of preblastoderm mitotic cell cycle progression" EXACT []
1148 xref: GO:0007347
1149
1150 [Term]
1151 id: CCO:P0000126
1152 name: regulation of progression through syncytial blastoderm mitotic cell cycle
1153 def: "A cell cycle process that modulates the frequency, rate or extent of the progression through the syncytial blastoderm mitotic cell cycle." [GOC:go_curators]
1154 is_a: CCO:P0000308 ! cell cycle process
1155 relationship: part_of CCO:P0000129 ! regulation of progression through embryonic mitotic cell cycle
1156 relationship: part_of CCO:P0000176 ! syncytial blastoderm mitotic cell cycle
1157 synonym: "syncytial blastoderm cell cycle regulator" RELATED []
1158 synonym: "control of syncytial blastoderm cell cycle progression" EXACT []
1159 synonym: "modulation of syncytial blastoderm cell cycle progression" EXACT []
1160 synonym: "regulation of syncytial blastoderm cell cycle" EXACT []
1161 synonym: "regulation of syncytial blastoderm cell cycle progression" EXACT []
1162 synonym: "syncytial blastoderm cell cycle control" EXACT []
1163 synonym: "syncytial blastoderm cell cycle modulation" EXACT []
1164 synonym: "syncytial blastoderm cell cycle regulation" EXACT []
1165 xref: GO:0007348
1166
1167 [Term]
1168 id: CCO:P0000127
1169 name: cyclin catabolic process
1170 def: "The chemical reactions and pathways resulting in the breakdown of cyclins, proteins whose levels in a cell varies markedly during the cell cycle, and which play key roles in regulating cell cycle phase transitions." [GOC:mah, http:cancerweb.ncl.ac.uk]
1171 is_a: CCO:P0000004 ! regulation of progression through cell cycle
1172 synonym: "cyclin breakdown" EXACT []
1173 synonym: "cyclin catabolism" EXACT []
1174 synonym: "cyclin degradation" EXACT []
1175 synonym: "degradation of cyclin" EXACT []
1176 xref: GO:0008054
1177
1178 [Term]
1179 id: CCO:P0000128
1180 name: meiotic G2/MI transition
1181 def: "The cell cycle process whereby a cell progresses from meiotic prophase to metaphase I." [PMID:15088480]
1182 is_a: CCO:P0000308 ! cell cycle process
1183 relationship: part_of CCO:P0000104 ! meiosis I
1184 xref: GO:0008315
1185
1186 [Term]
1187 id: CCO:P0000129
1188 name: regulation of progression through embryonic mitotic cell cycle
1189 def: "Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo." [GOC:go_curators]
1190 is_a: CCO:P0000124 ! regulation of progression through mitotic cell cycle
1191 relationship: part_of CCO:P0000193 ! mitotic cell cycle, embryonic
1192 synonym: "embryonic mitotic cell cycle regulator" RELATED []
1193 synonym: "control of embryonic mitotic cell cycle progression" EXACT []
1194 synonym: "embryonic mitotic cell cycle control" EXACT []
1195 synonym: "embryonic mitotic cell cycle modulation" EXACT []
1196 synonym: "embryonic mitotic cell cycle regulation" EXACT []
1197 synonym: "modulation of embryonic mitotic cell cycle progression" EXACT []
1198 synonym: "regulation of embryonic mitotic cell cycle" EXACT []
1199 synonym: "regulation of embryonic mitotic cell cycle progression" EXACT []
1200 synonym: "regulation of mitotic cell cycle, embryonic" EXACT []
1201 xref: GO:0009794
1202
1203 [Term]
1204 id: CCO:P0000130
1205 name: cell plate formation (sensu Magnoliophyta)
1206 def: "The cell cycle process whereby the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. As in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398)." [GOC:tb, ISBN:0879015322]
1207 is_a: CCO:P0000308 ! cell cycle process
1208 relationship: part_of CCO:P0000069 ! mitosis
1209 xref: GO:0009920
1210
1211 [Term]
1212 id: CCO:P0000131
1213 name: male meiotic spindle assembly (sensu Viridiplantae)
1214 def: "The formation of the spindle in male meiotic cells. As in, but not restricted to, green plants and algae (Viridiplantae, ncbi_taxonomy_id:33090)." [PMID:11973272]
1215 is_a: CCO:P0000242 ! meiotic spindle assembly
1216 relationship: part_of CCO:P0000117 ! male meiosis
1217 xref: GO:0009971
1218
1219 [Term]
1220 id: CCO:P0000132
1221 name: female meiosis chromosome segregation
1222 def: "The cell cycle process whereby genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." [GOC:ai]
1223 is_a: CCO:P0000189 ! meiotic chromosome segregation
1224 is_a: CCO:P0000308 ! cell cycle process
1225 relationship: part_of CCO:P0000120 ! female meiosis
1226 xref: GO:0016321
1227
1228 [Term]
1229 id: CCO:P0000133
1230 name: second mitotic wave (sensu Endopterygota)
1231 def: "A discrete cell cycle that occurs during the third instar eye imaginal disc after progression of the morphogenetic furrow. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia. As in, but not restricted to, the Holometabola (Endopterygota, ncbi_taxonomy_id:33392)." [PMID:11257224]
1232 is_a: CCO:P0000056 ! cell cycle
1233 xref: GO:0016330
1234
1235 [Term]
1236 id: CCO:P0000134
1237 name: meiotic chromosome movement towards spindle pole
1238 def: "The cell cycle process whereby the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis." [GOC:ai]
1239 is_a: CCO:P0000308 ! cell cycle process
1240 relationship: part_of CCO:P0000189 ! meiotic chromosome segregation
1241 synonym: "chromosome migration to spindle pole during meiosis" EXACT []
1242 synonym: "chromosome movement towards spindle pole during meiosis" EXACT []
1243 synonym: "meiotic chromosome movement to spindle pole" EXACT []
1244 synonym: "meiotic chromosome movement" BROAD []
1245 xref: GO:0016344
1246
1247 [Term]
1248 id: CCO:P0000135
1249 name: female meiotic chromosome movement towards spindle pole
1250 def: "The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis." [GOC:ai]
1251 is_a: CCO:P0000134 ! meiotic chromosome movement towards spindle pole
1252 relationship: part_of CCO:P0000132 ! female meiosis chromosome segregation
1253 synonym: "chromosome movement towards spindle pole during female meiosis" EXACT []
1254 synonym: "female meiotic chromosome movement to spindle pole" EXACT []
1255 synonym: "female meiotic chromosome movement" BROAD []
1256 xref: GO:0016345
1257
1258 [Term]
1259 id: CCO:P0000136
1260 name: male meiotic chromosome movement towards spindle pole
1261 def: "The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis." [GOC:ai]
1262 is_a: CCO:P0000134 ! meiotic chromosome movement towards spindle pole
1263 relationship: part_of CCO:P0000065 ! male meiosis chromosome segregation
1264 synonym: "chromosome movement towards spindle pole during male meiosis" EXACT []
1265 synonym: "male meiotic chromosome movement to spindle pole" EXACT []
1266 synonym: "male meiotic chromosome movement" BROAD []
1267 xref: GO:0016346
1268
1269 [Term]
1270 id: CCO:P0000137
1271 name: modification by virus of host cell cycle regulation
1272 def: "Viral processes that modulate the rate of the host cell cycle to facilitate virus replication." [ISBN:0781718325]
1273 is_a: CCO:P0000004 ! regulation of progression through cell cycle
1274 synonym: "viral perturbation of cell cycle regulation" EXACT []
1275 xref: GO:0019055
1276
1277 [Term]
1278 id: CCO:P0000138
1279 name: actin filament reorganization during cell cycle
1280 def: "The cell cycle process whereby rearrangement of the spatial distribution of actin filaments and associated proteins occurs." [GOC:mah]
1281 is_a: CCO:P0000308 ! cell cycle process
1282 synonym: "actin filament reorganisation during cell cycle" EXACT []
1283 xref: GO:0030037
1284
1285 [Term]
1286 id: CCO:P0000139
1287 name: regulation of mitotic metaphase/anaphase transition
1288 def: "Any process that modulates the frequency, rate or extent of the onset of anaphase (chromosome movement) in the mitotic cell cycle." [GOC:mah]
1289 is_a: CCO:P0000087 ! regulation of mitosis
1290 relationship: part_of CCO:P0000090 ! mitotic metaphase/anaphase transition
1291 xref: GO:0030071
1292
1293 [Term]
1294 id: CCO:P0000140
1295 name: mitotic spindle organization and biogenesis in nucleus
1296 def: "The formation and maintenance of the spindle in the nucleus, as seen in Fungi during a mitotic cell cycle." [GOC:mah]
1297 is_a: CCO:P0000058 ! mitotic spindle organization and biogenesis
1298 synonym: "mitotic spindle organisation and biogenesis in nucleus" EXACT []
1299 synonym: "spindle organization and biogenesis in nucleus during mitosis" EXACT []
1300 synonym: "mitotic spindle assembly (sensu Fungi)" NARROW []
1301 synonym: "mitotic spindle assembly (sensu Saccharomyces)" NARROW []
1302 xref: GO:0030472
1303 xref: GO:0000071
1304
1305 [Term]
1306 id: CCO:P0000141
1307 name: horsetail nuclear movement
1308 def: "The cell cycle process whereby oscillatory movement of the nucleus during meiotic prophase I occurs. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, which may facilitate synapsis necessary for efficient meiotic recombination; as observed in S. pombe." [PMID:16111942, PMID:9572142]
1309 is_a: CCO:P0000308 ! cell cycle process
1310 relationship: part_of CCO:P0000103 ! meiosis
1311 synonym: "HNM" EXACT []
1312 synonym: "horsetail movement" EXACT []
1313 xref: GO:0030989
1314
1315 [Term]
1316 id: CCO:P0000142
1317 name: cell cycle arrest in response to nitrogen starvation
1318 def: "The processes that lead to a halt in cell cycle progression (cessation of cell cycle transitions) as a result of deprivation of nitrogen." [GOC:vw]
1319 is_a: CCO:P0000057 ! cell cycle arrest
1320 xref: GO:0030996
1321
1322 [Term]
1323 id: CCO:P0000143
1324 name: regulation of centriole-centriole cohesion
1325 def: "Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker." [PMID:11076968]
1326 relationship: part_of CCO:P0000096 ! centrosome cycle
1327 xref: GO:0030997
1328
1329 [Term]
1330 id: CCO:P0000144
1331 name: linear element formation
1332 def: "The cell cycle process whereby a proteinaceous scaffold, related to the synaptonemal complex, is formed in association with S. pombe chromosomes during meiotic prophase." [GOC:mah, Sanger:jb]
1333 is_a: CCO:P0000308 ! cell cycle process
1334 relationship: part_of CCO:P0000106 ! synapsis
1335 xref: GO:0030999
1336
1337 [Term]
1338 id: CCO:P0000145
1339 name: septation initiation signaling
1340 def: "The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the begining of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis." [GOC:mah, GOC:vw, PMID:16775007]
1341 is_a: CCO:P0000173 ! regulation of contractile ring contraction during cytokinesis
1342 synonym: "septation initiation network" EXACT []
1343 synonym: "septation initiation signalling" EXACT []
1344 synonym: "SIN" EXACT []
1345 xref: GO:0031028
1346
1347 [Term]
1348 id: CCO:P0000146
1349 name: regulation of septation initiation signaling
1350 def: "Any process that modulates the frequency, rate or extent of septation initiation signaling." [GOC:mah]
1351 relationship: part_of CCO:P0000145 ! septation initiation signaling
1352 synonym: "regulation of septation initiation network" EXACT []
1353 synonym: "regulation of septation initiation signalling" EXACT []
1354 xref: GO:0031029
1355
1356 [Term]
1357 id: CCO:P0000147
1358 name: negative regulation of septation initiation signaling
1359 def: "Any process that stops, prevents or reduces the frequency, rate or extent of septation initiation signaling." [GOC:mah]
1360 is_a: CCO:P0000146 ! regulation of septation initiation signaling
1361 synonym: "down regulation of septation initiation signaling" EXACT []
1362 synonym: "down-regulation of septation initiation signaling" EXACT []
1363 synonym: "downregulation of septation initiation signaling" EXACT []
1364 synonym: "negative regulation of septation initiation network" EXACT []
1365 synonym: "negative regulation of septation initiation signalling" EXACT []
1366 synonym: "inhibition of septation initiation signaling" NARROW []
1367 xref: GO:0031030
1368
1369 [Term]
1370 id: CCO:P0000148
1371 name: positive regulation of septation initiation signaling
1372 def: "Any process that activates or increases the frequency, rate or extent of septation initiation signaling." [GOC:mah]
1373 is_a: CCO:P0000146 ! regulation of septation initiation signaling
1374 synonym: "positive regulation of septation initiation network" EXACT []
1375 synonym: "positive regulation of septation initiation signalling" EXACT []
1376 synonym: "up regulation of septation initiation signaling" EXACT []
1377 synonym: "up-regulation of septation initiation signaling" EXACT []
1378 synonym: "upregulation of septation initiation signaling" EXACT []
1379 synonym: "activation of septation initiation signaling" NARROW []
1380 synonym: "stimulation of septation initiation signaling" NARROW []
1381 xref: GO:0031031
1382
1383 [Term]
1384 id: CCO:P0000149
1385 name: sister chromatid biorientation
1386 def: "The cell cycle process whereby sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles." [PMID:15309047]
1387 is_a: CCO:P0000308 ! cell cycle process
1388 relationship: part_of CCO:P0000082 ! mitotic metaphase plate congression
1389 synonym: "chromosome biorientation" EXACT []
1390 synonym: "sister kinetochore biorientation" EXACT []
1391 xref: GO:0031134
1392
1393 [Term]
1394 id: CCO:P0000150
1395 name: collapsed replication fork processing
1396 def: "The process by which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired by a recombinational mechanism." [PMID:11459955, PMID:15367656]
1397 relationship: part_of CCO:P0000160 ! intra-S DNA damage checkpoint
1398 xref: GO:0031297
1399
1400 [Term]
1401 id: CCO:P0000151
1402 name: positive regulation of exit from mitosis
1403 def: "Any processactivates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)." [GOC:mah]
1404 is_a: CCO:P0000095 ! regulation of exit from mitosis
1405 synonym: "up regulation of exit from mitosis" EXACT []
1406 synonym: "up-regulation of exit from mitosis" EXACT []
1407 synonym: "upregulation of exit from mitosis" EXACT []
1408 synonym: "activation of exit from mitosis" NARROW []
1409 synonym: "stimulation of exit from mitosis" NARROW []
1410 xref: GO:0031536
1411
1412 [Term]
1413 id: CCO:P0000152
1414 name: cytokinesis checkpoint
1415 def: "A cell cycle checkpoint that ensures the correct temporal ordering of nuclear division and cytokinesis; arrests the cell cycle in G2 upon perturbation of cytokinetic structures. In Schizosaccharomyces, the checkpoint monitors formation and integrity of medial actomyosin ring and septum." [GOC:mah, PMID:15647375]
1416 is_a: CCO:P0000005 ! cell cycle checkpoint
1417 synonym: "contractile ring checkpoint" EXACT []
1418 xref: GO:0031565
1419
1420 [Term]
1421 id: CCO:P0000153
1422 name: cytokinesis, contractile ring maintenance
1423 def: "The cell cycle process whereby the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures." [GOC:vw]
1424 is_a: CCO:P0000308 ! cell cycle process
1425 relationship: part_of CCO:P0000152 ! cytokinesis checkpoint
1426 xref: GO:0031566
1427
1428 [Term]
1429 id: CCO:P0000154
1430 name: cell size control checkpoint
1431 def: "Any cell cycle checkpoint that delays or arrests cell cycle progression until cells have reached a critical size." [GOC:mah]
1432 is_a: CCO:P0000005 ! cell cycle checkpoint
1433 xref: GO:0031567
1434
1435 [Term]
1436 id: CCO:P0000155
1437 name: G1/S transition size control checkpoint
1438 def: "A cell cycle checkpoint that blocks cell cycle progression from G1 to S phase until cells have reached a critical size." [GOC:mah]
1439 is_a: CCO:P0000154 ! cell size control checkpoint
1440 is_a: CCO:P0000162 ! G1/S transition checkpoint
1441 xref: GO:0031568
1442
1443 [Term]
1444 id: CCO:P0000156
1445 name: G2/M transition size control checkpoint
1446 def: "A cell cycle checkpoint that blocks cell cycle progression from G2 to M phase until cells have reached a critical size." [GOC:mah]
1447 is_a: CCO:P0000154 ! cell size control checkpoint
1448 is_a: CCO:P0000163 ! G2/M transition checkpoint
1449 xref: GO:0031569
1450
1451 [Term]
1452 id: CCO:P0000157
1453 name: DNA integrity checkpoint
1454 def: "Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure." [GOC:mah, GOC:vw]
1455 is_a: CCO:P0000005 ! cell cycle checkpoint
1456 xref: GO:0031570
1457
1458 [Term]
1459 id: CCO:P0000158
1460 name: G1 DNA damage checkpoint
1461 def: "A cell cycle checkpoint that arrests cell cycle progression G1 phase in response to DNA damage." [GOC:mah]
1462 is_a: CCO:P0000007 ! DNA damage checkpoint
1463 xref: GO:0031571
1464
1465 [Term]
1466 id: CCO:P0000159
1467 name: G2/M transition DNA damage checkpoint
1468 def: "A cell cycle checkpoint that blocks cell cycle progression from G2 to M phase in response to DNA damage." [GOC:mah]
1469 is_a: CCO:P0000007 ! DNA damage checkpoint
1470 is_a: CCO:P0000163 ! G2/M transition checkpoint
1471 xref: GO:0031572
1472
1473 [Term]
1474 id: CCO:P0000160
1475 name: intra-S DNA damage checkpoint
1476 def: "The slowing of DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progession." [GOC:vw]
1477 is_a: CCO:P0000007 ! DNA damage checkpoint
1478 xref: GO:0031573
1479
1480 [Term]
1481 id: CCO:P0000161
1482 name: S-M checkpoint
1483 def: "A cell cycle checkpoint which halts replication in response to nucleotide depletion." [GOC:vw]
1484 is_a: CCO:P0000160 ! intra-S DNA damage checkpoint
1485 xref: GO:0031574
1486
1487 [Term]
1488 id: CCO:P0000162
1489 name: G1/S transition checkpoint
1490 def: "Any cell cycle checkpoint that blocks entry into S phase." [GOC:mah]
1491 is_a: CCO:P0000005 ! cell cycle checkpoint
1492 xref: GO:0031575
1493
1494 [Term]
1495 id: CCO:P0000163
1496 name: G2/M transition checkpoint
1497 def: "Any cell cycle checkpoint that blocks entry into M phase." [GOC:mah]
1498 is_a: CCO:P0000005 ! cell cycle checkpoint
1499 synonym: "G2/M checkpoint" EXACT []
1500 xref: GO:0031576
1501
1502 [Term]
1503 id: CCO:P0000164
1504 name: spindle checkpoint
1505 def: "A cell cycle checkpoint that delays the metaphase/anaphase transition until all chromosomes are attached to the spindle." [PMID:15897186]
1506 is_a: CCO:P0000005 ! cell cycle checkpoint
1507 synonym: "spindle assembly checkpoint" EXACT []
1508 synonym: "SAC" BROAD []
1509 xref: GO:0031577
1510
1511 [Term]
1512 id: CCO:P0000165
1513 name: spindle orientation checkpoint
1514 def: "A cell cycle checkpoint that monitors and signals errors in the placement or orientation of the spindle in the cell. The result is a cell cycle delay, usually in mitosis, until errors are corrected." [GOC:clt, PMID:14616062]
1515 is_a: CCO:P0000005 ! cell cycle checkpoint
1516 synonym: "SOC" EXACT []
1517 synonym: "spindle position checkpoint" EXACT []
1518 synonym: "SPOC" EXACT []
1519 xref: GO:0031578
1520
1521 [Term]
1522 id: CCO:P0000166
1523 name: homologous chromosome orientation during meiosis
1524 def: "The cell cycle process whereby the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I." [PMID:15062096]
1525 is_a: CCO:P0000308 ! cell cycle process
1526 relationship: part_of CCO:P0000183 ! meiotic metaphase I plate congression
1527 synonym: "homologous chromosome orientation during meiosis I" EXACT []
1528 xref: GO:0031619
1529
1530 [Term]
1531 id: CCO:P0000167
1532 name: G1/S-specific regulation of cyclin-dependent protein kinase activity
1533 def: "Any process that modulates the frequency, rate or extent of CDK activity during the G1/S transition of the cell cycle." [GOC:mah]
1534 is_a: CCO:P0000009 ! regulation of cyclin-dependent protein kinase activity
1535 relationship: part_of CCO:P0000011 ! G1/S transition of mitotic cell cycle
1536 xref: GO:0031657
1537
1538 [Term]
1539 id: CCO:P0000168
1540 name: G1/S-specific negative regulation of cyclin-dependent protein kinase activity
1541 def: "Any process that stops, prevents or reduces the frequency, rate or extent of CDK activity during the G1/S transition of the cell cycle." [GOC:mah]
1542 is_a: CCO:P0000167 ! G1/S-specific regulation of cyclin-dependent protein kinase activity
1543 is_a: CCO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
1544 synonym: "G1/S-specific down regulation of cyclin-dependent protein kinase activity" EXACT []
1545 synonym: "G1/S-specific down-regulation of cyclin-dependent protein kinase activity" EXACT []
1546 synonym: "G1/S-specific downregulation of cyclin-dependent protein kinase activity" EXACT []
1547 synonym: "G1/S-specific inhibition of cyclin-dependent protein kinase activity" NARROW []
1548 xref: GO:0031658
1549
1550 [Term]
1551 id: CCO:P0000169
1552 name: G1/S-specific positive regulation of cyclin-dependent protein kinase activity
1553 def: "Any process that activates or increases the frequency, rate or extent of CDK activity during the G1/S transition of the cell cycle." [GOC:mah]
1554 is_a: CCO:P0000167 ! G1/S-specific regulation of cyclin-dependent protein kinase activity
1555 is_a: CCO:P0000195 ! positive regulation of cyclin-dependent protein kinase activity
1556 synonym: "G1/S-specific up regulation of cyclin-dependent protein kinase activity" EXACT []
1557 synonym: "G1/S-specific up-regulation of cyclin-dependent protein kinase activity" EXACT []
1558 synonym: "G1/S-specific upregulation of cyclin-dependent protein kinase activity" EXACT []
1559 synonym: "G1/S-specific activation of cyclin-dependent protein kinase activity" NARROW []
1560 synonym: "G1/S-specific stimulation of cyclin-dependent protein kinase activity" NARROW []
1561 xref: GO:0031659
1562
1563 [Term]
1564 id: CCO:P0000170
1565 name: G2/M-specific regulation of cyclin-dependent protein kinase activity
1566 def: "Any process that modulates the frequency, rate or extent of CDK activity during the G2/M transition of the cell cycle." [GOC:mah]
1567 is_a: CCO:P0000009 ! regulation of cyclin-dependent protein kinase activity
1568 relationship: part_of CCO:P0000015 ! G2/M transition of mitotic cell cycle
1569 xref: GO:0031660
1570
1571 [Term]
1572 id: CCO:P0000171
1573 name: G2/M-specific negative regulation of cyclin-dependent protein kinase activity
1574 def: "Any process that stops, prevents or reduces the frequency, rate or extent of CDK activity during the G2/M transition of the cell cycle." [GOC:mah]
1575 is_a: CCO:P0000170 ! G2/M-specific regulation of cyclin-dependent protein kinase activity
1576 is_a: CCO:P0000194 ! negative regulation of cyclin-dependent protein kinase activity
1577 synonym: "G2/M-specific down regulation of cyclin-dependent protein kinase activity" EXACT []
1578 synonym: "G2/M-specific down-regulation of cyclin-dependent protein kinase activity" EXACT []
1579 synonym: "G2/M-specific downregulation of cyclin-dependent protein kinase activity" EXACT []
1580 synonym: "G2/M-specific inhibition of cyclin-dependent protein kinase activity" NARROW []
1581 xref: GO:0031661
1582
1583 [Term]
1584 id: CCO:P0000172
1585 name: G2/M-specific positive regulation of cyclin-dependent protein kinase activity
1586 def: "Any process that activates or increases the frequency, rate or extent of CDK activity during the G2/M transition of the cell cycle." [GOC:mah]
1587 is_a: CCO:P0000170 ! G2/M-specific regulation of cyclin-dependent protein kinase activity
1588 is_a: CCO:P0000195 ! positive regulation of cyclin-dependent protein kinase activity
1589 synonym: "G2/M-specific up regulation of cyclin-dependent protein kinase activity" EXACT []
1590 synonym: "G2/M-specific up-regulation of cyclin-dependent protein kinase activity" EXACT []
1591 synonym: "G2/M-specific upregulation of cyclin-dependent protein kinase activity" EXACT []
1592 synonym: "G2/M-specific activation of cyclin-dependent protein kinase activity" NARROW []
1593 synonym: "G2/M-specific stimulation of cyclin-dependent protein kinase activity" NARROW []
1594 xref: GO:0031662
1595
1596 [Term]
1597 id: CCO:P0000173
1598 name: regulation of contractile ring contraction during cytokinesis
1599 def: "Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring during cytokinesis." [GOC:mah]
1600 is_a: CCO:P0000004 ! regulation of progression through cell cycle
1601 xref: GO:0031991
1602
1603 [Term]
1604 id: CCO:P0000174
1605 name: attachment of telomeres to spindle pole body
1606 def: "The cell cycle process whereby physical connections are formed between telomeres and the spindle pole body, facilitating bouquet formation." [PMID:16615890]
1607 is_a: CCO:P0000308 ! cell cycle process
1608 relationship: part_of CCO:P0000190 ! telomere clustering
1609 xref: GO:0032121
1610
1611 [Term]
1612 id: CCO:P0000175
1613 name: preblastoderm mitotic cell cycle
1614 def: "The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis." [ISBN:0879694238]
1615 is_a: CCO:P0000193 ! mitotic cell cycle, embryonic
1616 xref: GO:0035185
1617
1618 [Term]
1619 id: CCO:P0000176
1620 name: syncytial blastoderm mitotic cell cycle
1621 def: "Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively." [ISBN:0879694238]
1622 is_a: CCO:P0000193 ! mitotic cell cycle, embryonic
1623 xref: GO:0035186
1624
1625 [Term]
1626 id: CCO:P0000177
1627 name: establishment of mitotic spindle localization
1628 def: "The cell cycle process whereby the directed movement of the mitotic spindle to a specific location in the cell occurs." [GOC:ai]
1629 is_a: CCO:P0000308 ! cell cycle process
1630 relationship: part_of CCO:P0000037 ! mitotic cell cycle
1631 synonym: "mitotic spindle positioning" EXACT []
1632 synonym: "mitotic spindle positioning or orientation" EXACT []
1633 synonym: "spindle positioning during mitosis" EXACT []
1634 synonym: "mitotic spindle positioning (sensu Fungi)" NARROW []
1635 synonym: "mitotic spindle positioning (sensu Saccharomyces)" NARROW []
1636 synonym: "mitotic spindle positioning and orientation (sensu Saccharomyces)" NARROW []
1637 synonym: "mitotic spindle positioning or orientation (sensu Fungi)" NARROW []
1638 xref: GO:0040001
1639 xref: GO:0018986
1640 xref: GO:0030605
1641 xref: GO:0030606
1642 xref: GO:0030608
1643 xref: GO:0030610
1644
1645 [Term]
1646 id: CCO:P0000178
1647 name: regulation of meiosis
1648 def: "Any process that modulates the frequency, rate or extent of meiosis, the process by which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." [GOC:ems, GOC:ma]
1649 is_a: CCO:P0000004 ! regulation of progression through cell cycle
1650 relationship: part_of CCO:P0000103 ! meiosis
1651 xref: GO:0040020
1652
1653 [Term]
1654 id: CCO:P0000179
1655 name: polar body extrusion after meiotic divisions
1656 def: "The cell cycle process whereby two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes." [GOC:ems, ISBN:0198506732]
1657 is_a: CCO:P0000308 ! cell cycle process
1658 relationship: part_of CCO:P0000120 ! female meiosis
1659 xref: GO:0040038
1660
1661 [Term]
1662 id: CCO:P0000180
1663 name: meiotic DNA double-strand break formation
1664 def: "The cell cycle process whereby double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination." [GOC:elh, GOC:jl, PMID:11529427]
1665 is_a: CCO:P0000308 ! cell cycle process
1666 relationship: part_of CCO:P0000054 ! meiotic gene conversion
1667 relationship: part_of CCO:P0000108 ! meiotic recombination
1668 xref: GO:0042138
1669
1670 [Term]
1671 id: CCO:P0000181
1672 name: early meiotic recombination nodule assembly
1673 def: "The assembly of small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene." [GOC:jl, PMID:9334324]
1674 is_a: CCO:P0000122 ! meiotic recombination nodule assembly
1675 xref: GO:0042139
1676
1677 [Term]
1678 id: CCO:P0000182
1679 name: late meiotic recombination nodule assembly
1680 def: "The assembly of small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over." [GOC:jl, PMID:9334324]
1681 is_a: CCO:P0000122 ! meiotic recombination nodule assembly
1682 xref: GO:0042140
1683
1684 [Term]
1685 id: CCO:P0000183
1686 name: meiotic metaphase I plate congression
1687 def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I." [GOC:cab1, PMID:10809666]
1688 is_a: CCO:P0000257 ! meiotic metaphase plate congression
1689 relationship: part_of CCO:P0000191 ! homologous chromosome segregation
1690 xref: GO:0043060
1691
1692 [Term]
1693 id: CCO:P0000184
1694 name: meiotic metaphase II plate congression
1695 def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis II." [GOC:cab1, PMID:10809666]
1696 is_a: CCO:P0000257 ! meiotic metaphase plate congression
1697 relationship: part_of CCO:P0000192 ! meiotic sister chromatid segregation
1698 xref: GO:0043061
1699
1700 [Term]
1701 id: CCO:P0000185
1702 name: meiotic spindle stabilization
1703 def: "The cell cycle process whereby spindle integrity is maintained during M phase of meiosis." [GOC:go_curators]
1704 is_a: CCO:P0000308 ! cell cycle process
1705 relationship: part_of CCO:P0000029 ! meiotic spindle organization and biogenesis
1706 xref: GO:0043147
1707
1708 [Term]
1709 id: CCO:P0000186
1710 name: mitotic spindle stabilization
1711 def: "The cell cycle process whereby spindle integrity is maintained during M phase of mitosis." [GOC:go_curators]
1712 is_a: CCO:P0000308 ! cell cycle process
1713 relationship: part_of CCO:P0000058 ! mitotic spindle organization and biogenesis
1714 xref: GO:0043148
1715
1716 [Term]
1717 id: CCO:P0000187
1718 name: G0 to G1 transition
1719 def: "The transition from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression." [ISBN:0716731363]
1720 is_a: CCO:P0000040 ! re-entry into mitotic cell cycle
1721 xref: GO:0045023
1722
1723 [Term]
1724 id: CCO:P0000188
1725 name: negative regulation of meiotic recombination
1726 def: "Any process that stops, prevents or reduces the frequency, rate or extent of recombination during meiosis." [GOC:ai]
1727 is_a: CCO:P0000200 ! negative regulation of meiosis
1728 relationship: part_of CCO:P0000108 ! meiotic recombination
1729 synonym: "down regulation of meiotic recombination" EXACT []
1730 synonym: "down-regulation of meiotic recombination" EXACT []
1731 synonym: "downregulation of meiotic recombination" EXACT []
1732 synonym: "suppression of meiotic recombination" EXACT []
1733 synonym: "inhibition of meiotic recombination" NARROW []
1734 xref: GO:0045128
1735
1736 [Term]
1737 id: CCO:P0000189
1738 name: meiotic chromosome segregation
1739 def: "The process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle." [GOC:ai]
1740 relationship: part_of CCO:P0000103 ! meiosis
1741 xref: GO:0045132
1742
1743 [Term]
1744 id: CCO:P0000190
1745 name: telomere clustering
1746 def: "The cell cycle process whereby the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in homologous chromosome pairing and therefore progression through meiosis." [GOC:vw, PMID:10690419]
1747 is_a: CCO:P0000308 ! cell cycle process
1748 relationship: part_of CCO:P0000103 ! meiosis
1749 synonym: "bouquet biosynthesis" NARROW []
1750 synonym: "bouquet formation" NARROW []
1751 xref: GO:0045141
1752
1753 [Term]
1754 id: CCO:P0000191
1755 name: homologous chromosome segregation
1756 def: "The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, ISBN:0815316194]
1757 is_a: CCO:P0000308 ! cell cycle process
1758 relationship: part_of CCO:P0000104 ! meiosis I
1759 relationship: part_of CCO:P0000189 ! meiotic chromosome segregation
1760 synonym: "meiosis I, chromosome segregation" EXACT []
1761 xref: GO:0045143
1762 xref: GO:0007061
1763
1764 [Term]
1765 id: CCO:P0000192
1766 name: meiotic sister chromatid segregation
1767 def: "The cell cycle process whereby sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." [GOC:ai, ISBN:0815316194]
1768 is_a: CCO:P0000308 ! cell cycle process
1769 relationship: part_of CCO:P0000112 ! meiosis II
1770 relationship: part_of CCO:P0000189 ! meiotic chromosome segregation
1771 synonym: "meiosis II, chromosome segregation" EXACT []
1772 xref: GO:0045144
1773
1774 [Term]
1775 id: CCO:P0000193
1776 name: mitotic cell cycle, embryonic
1777 def: "The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo." [GOC:go_curators]
1778 is_a: CCO:P0000037 ! mitotic cell cycle
1779 xref: GO:0045448
1780
1781 [Term]
1782 id: CCO:P0000194
1783 name: negative regulation of cyclin-dependent protein kinase activity
1784 def: "Any process that stops, prevents or reduces the frequency, rate or extent of CDK activity." [GOC:go_curators]
1785 is_a: CCO:P0000009 ! regulation of cyclin-dependent protein kinase activity
1786 is_a: CCO:P0000198 ! negative regulation of progression through cell cycle
1787 synonym: "CDK inhibitor" RELATED []
1788 synonym: "cyclin-dependent kinase inhibitor" RELATED []
1789 synonym: "down regulation of cyclin-dependent protein kinase activity" EXACT []
1790 synonym: "down-regulation of cyclin-dependent protein kinase activity" EXACT []
1791 synonym: "downregulation of cyclin-dependent protein kinase activity" EXACT []
1792 synonym: "negative regulation of CDK activity" EXACT []
1793 synonym: "inhibition of cyclin-dependent protein kinase activity" NARROW []
1794 xref: GO:0045736
1795
1796 [Term]
1797 id: CCO:P0000195
1798 name: positive regulation of cyclin-dependent protein kinase activity
1799 def: "Any process that activates or increases the frequency, rate or extent of CDK activity." [GOC:go_curators]
1800 is_a: CCO:P0000009 ! regulation of cyclin-dependent protein kinase activity
1801 is_a: CCO:P0000199 ! positive regulation of progression through cell cycle
1802 synonym: "positive regulation of CDK activity" EXACT []
1803 synonym: "up regulation of cyclin-dependent protein kinase activity" EXACT []
1804 synonym: "up-regulation of cyclin-dependent protein kinase activity" EXACT []
1805 synonym: "upregulation of cyclin-dependent protein kinase activity" EXACT []
1806 synonym: "activation of cyclin-dependent protein kinase activity" NARROW []
1807 synonym: "stimulation of cyclin-dependent protein kinase activity" NARROW []
1808 xref: GO:0045737
1809
1810 [Term]
1811 id: CCO:P0000196
1812 name: negative regulation of S phase of mitotic cell cycle
1813 def: "Any process that stops, prevents or reduces the frequency, rate or extent of S phase of mitotic cell cycle activity." [GOC:go_curators]
1814 is_a: CCO:P0000089 ! regulation of S phase of mitotic cell cycle
1815 is_a: CCO:P0000208 ! negative regulation of progression through mitotic cell cycle
1816 synonym: "down regulation of S phase of mitotic cell cycle" EXACT []
1817 synonym: "down-regulation of S phase of mitotic cell cycle" EXACT []
1818 synonym: "downregulation of S phase of mitotic cell cycle" EXACT []
1819 synonym: "inhibition of S phase of mitotic cell cycle" NARROW []
1820 xref: GO:0045749
1821
1822 [Term]
1823 id: CCO:P0000197
1824 name: positive regulation of S phase of mitotic cell cycle
1825 def: "Any process that activates or increases the frequency, rate or extent of S phase of mitotic cell cycle activity." [GOC:go_curators]
1826 is_a: CCO:P0000089 ! regulation of S phase of mitotic cell cycle
1827 is_a: CCO:P0000209 ! positive regulation of progression through mitotic cell cycle
1828 synonym: "up regulation of S phase of mitotic cell cycle" EXACT []
1829 synonym: "up-regulation of S phase of mitotic cell cycle" EXACT []
1830 synonym: "upregulation of S phase of mitotic cell cycle" EXACT []
1831 synonym: "activation of S phase of mitotic cell cycle" NARROW []
1832 synonym: "stimulation of S phase of mitotic cell cycle" NARROW []
1833 xref: GO:0045750
1834
1835 [Term]
1836 id: CCO:P0000198
1837 name: negative regulation of progression through cell cycle
1838 def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the cell cycle." [GOC:go_curators]
1839 is_a: CCO:P0000004 ! regulation of progression through cell cycle
1840 synonym: "down regulation of progression through cell cycle" EXACT []
1841 synonym: "down-regulation of progression through cell cycle" EXACT []
1842 synonym: "downregulation of progression through cell cycle" EXACT []
1843 synonym: "negative regulation of cell cycle progression" EXACT []
1844 synonym: "inhibition of progression through cell cycle" NARROW []
1845 xref: GO:0045786
1846
1847 [Term]
1848 id: CCO:P0000199
1849 name: positive regulation of progression through cell cycle
1850 def: "Any process that activates or increases the frequency, rate or extent of progression through the cell cycle." [GOC:go_curators]
1851 is_a: CCO:P0000004 ! regulation of progression through cell cycle
1852 synonym: "positive regulation of cell cycle progression" EXACT []
1853 synonym: "up regulation of progression through cell cycle" EXACT []
1854 synonym: "up-regulation of progression through cell cycle" EXACT []
1855 synonym: "upregulation of progression through cell cycle" EXACT []
1856 synonym: "activation of progression through cell cycle" NARROW []
1857 synonym: "stimulation of progression through cell cycle" NARROW []
1858 xref: GO:0045787
1859
1860 [Term]
1861 id: CCO:P0000200
1862 name: negative regulation of meiosis
1863 def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiosis." [GOC:go_curators]
1864 is_a: CCO:P0000178 ! regulation of meiosis
1865 synonym: "down regulation of meiosis" EXACT []
1866 synonym: "down-regulation of meiosis" EXACT []
1867 synonym: "downregulation of meiosis" EXACT []
1868 synonym: "inhibition of meiosis" NARROW []
1869 xref: GO:0045835
1870
1871 [Term]
1872 id: CCO:P0000201
1873 name: positive regulation of meiosis
1874 def: "Any process that activates or increases the frequency, rate or extent of meiosis." [GOC:go_curators]
1875 is_a: CCO:P0000178 ! regulation of meiosis
1876 synonym: "up regulation of meiosis" EXACT []
1877 synonym: "up-regulation of meiosis" EXACT []
1878 synonym: "upregulation of meiosis" EXACT []
1879 synonym: "activation of meiosis" NARROW []
1880 synonym: "stimulation of meiosis" NARROW []
1881 xref: GO:0045836
1882
1883 [Term]
1884 id: CCO:P0000202
1885 name: negative regulation of mitosis
1886 def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitosis." [GOC:go_curators]
1887 is_a: CCO:P0000087 ! regulation of mitosis
1888 is_a: CCO:P0000198 ! negative regulation of progression through cell cycle
1889 synonym: "down regulation of mitosis" EXACT []
1890 synonym: "down-regulation of mitosis" EXACT []
1891 synonym: "downregulation of mitosis" EXACT []
1892 synonym: "inhibition of mitosis" NARROW []
1893 xref: GO:0045839
1894
1895 [Term]
1896 id: CCO:P0000203
1897 name: positive regulation of mitosis
1898 def: "Any process that activates or increases the frequency, rate or extent of mitosis." [GOC:go_curators]
1899 is_a: CCO:P0000087 ! regulation of mitosis
1900 is_a: CCO:P0000199 ! positive regulation of progression through cell cycle
1901 synonym: "up regulation of mitosis" EXACT []
1902 synonym: "up-regulation of mitosis" EXACT []
1903 synonym: "upregulation of mitosis" EXACT []
1904 synonym: "activation of mitosis" NARROW []
1905 synonym: "mitogenic activity" NARROW []
1906 synonym: "stimulation of mitosis" NARROW []
1907 xref: GO:0045840
1908
1909 [Term]
1910 id: CCO:P0000204
1911 name: negative regulation of mitotic metaphase/anaphase transition
1912 def: "Any process that stops, prevents or reduces the frequency, rate or extent of the mitotic metaphase to anaphase transition." [GOC:go_curators]
1913 is_a: CCO:P0000139 ! regulation of mitotic metaphase/anaphase transition
1914 is_a: CCO:P0000202 ! negative regulation of mitosis
1915 synonym: "down regulation of mitotic metaphase/anaphase transition" EXACT []
1916 synonym: "down-regulation of mitotic metaphase/anaphase transition" EXACT []
1917 synonym: "downregulation of mitotic metaphase/anaphase transition" EXACT []
1918 synonym: "inhibition of mitotic metaphase/anaphase transition" NARROW []
1919 xref: GO:0045841
1920
1921 [Term]
1922 id: CCO:P0000205
1923 name: positive regulation of mitotic metaphase/anaphase transition
1924 def: "Any process that activates or increases the frequency, rate or extent of the mitotic metaphase to anaphase transition." [GOC:go_curators]
1925 is_a: CCO:P0000139 ! regulation of mitotic metaphase/anaphase transition
1926 is_a: CCO:P0000203 ! positive regulation of mitosis
1927 synonym: "up regulation of mitotic metaphase/anaphase transition" EXACT []
1928 synonym: "up-regulation of mitotic metaphase/anaphase transition" EXACT []
1929 synonym: "upregulation of mitotic metaphase/anaphase transition" EXACT []
1930 synonym: "activation of mitotic metaphase/anaphase transition" NARROW []
1931 synonym: "stimulation of mitotic metaphase/anaphase transition" NARROW []
1932 xref: GO:0045842
1933
1934 [Term]
1935 id: CCO:P0000206
1936 name: regulation of transcription, mitotic
1937 def: "A cell cycle process that modulates the frequency, rate or extent of transcription during mitosis." [GOC:go_curators]
1938 is_a: CCO:P0000308 ! cell cycle process
1939 relationship: part_of CCO:P0000069 ! mitosis
1940 synonym: "mitotic regulation of transcription" EXACT []
1941 xref: GO:0045896
1942
1943 [Term]
1944 id: CCO:P0000207
1945 name: positive regulation of transcription, mitotic
1946 def: "Any process that activates or increases the frequency, rate or extent of transcription during mitosis." [GOC:go_curators]
1947 is_a: CCO:P0000206 ! regulation of transcription, mitotic
1948 synonym: "mitotic activation of transcription" EXACT []
1949 synonym: "up regulation of transcription, mitotic" EXACT []
1950 synonym: "up-regulation of transcription, mitotic" EXACT []
1951 synonym: "upregulation of transcription, mitotic" EXACT []
1952 synonym: "activation of transcription, mitotic" NARROW []
1953 synonym: "stimulation of transcription, mitotic" NARROW []
1954 xref: GO:0045897
1955
1956 [Term]
1957 id: CCO:P0000208
1958 name: negative regulation of progression through mitotic cell cycle
1959 def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the mitotic cell cycle." [GOC:go_curators]
1960 is_a: CCO:P0000124 ! regulation of progression through mitotic cell cycle
1961 is_a: CCO:P0000198 ! negative regulation of progression through cell cycle
1962 synonym: "down regulation of progression through mitotic cell cycle" EXACT []
1963 synonym: "down-regulation of progression through mitotic cell cycle" EXACT []
1964 synonym: "downregulation of progression through mitotic cell cycle" EXACT []
1965 synonym: "negative regulation of mitotic cell cycle" EXACT []
1966 synonym: "negative regulation of mitotic cell cycle progression" EXACT []
1967 synonym: "inhibition of progression through mitotic cell cycle" NARROW []
1968 xref: GO:0045930
1969
1970 [Term]
1971 id: CCO:P0000209
1972 name: positive regulation of progression through mitotic cell cycle
1973 def: "Any process that activates or increases the frequency, rate or extent of progression through the mitotic cell cycle." [GOC:go_curators]
1974 is_a: CCO:P0000124 ! regulation of progression through mitotic cell cycle
1975 is_a: CCO:P0000199 ! positive regulation of progression through cell cycle
1976 synonym: "positive regulation of mitotic cell cycle" EXACT []
1977 synonym: "positive regulation of mitotic cell cycle progression" EXACT []
1978 synonym: "up regulation of progression through mitotic cell cycle" EXACT []
1979 synonym: "up-regulation of progression through mitotic cell cycle" EXACT []
1980 synonym: "upregulation of progression through mitotic cell cycle" EXACT []
1981 synonym: "activation of progression through mitotic cell cycle" NARROW []
1982 synonym: "stimulation of progression through mitotic cell cycle" NARROW []
1983 xref: GO:0045931
1984
1985 [Term]
1986 id: CCO:P0000210
1987 name: negative regulation of progression through embryonic mitotic cell cycle
1988 def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the embryonic mitotic cell cycle." [GOC:go_curators]
1989 is_a: CCO:P0000129 ! regulation of progression through embryonic mitotic cell cycle
1990 is_a: CCO:P0000208 ! negative regulation of progression through mitotic cell cycle
1991 synonym: "down regulation of progression through embryonic mitotic cell cycle" EXACT []
1992 synonym: "down-regulation of progression through embryonic mitotic cell cycle" EXACT []
1993 synonym: "downregulation of progression through embryonic mitotic cell cycle" EXACT []
1994 synonym: "negative regulation of embryonic mitotic cell cycle progression" EXACT []
1995 synonym: "inhibition of progression through embryonic mitotic cell cycle" NARROW []
1996 xref: GO:0045976
1997
1998 [Term]
1999 id: CCO:P0000211
2000 name: positive regulation of mitotic cell cycle, embryonic
2001 def: "Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle." [GOC:go_curators]
2002 is_a: CCO:P0000129 ! regulation of progression through embryonic mitotic cell cycle
2003 is_a: CCO:P0000209 ! positive regulation of progression through mitotic cell cycle
2004 synonym: "positive regulation of embryonic mitotic cell cycle progression" EXACT []
2005 synonym: "up regulation of mitotic cell cycle, embryonic" EXACT []
2006 synonym: "up-regulation of mitotic cell cycle, embryonic" EXACT []
2007 synonym: "upregulation of mitotic cell cycle, embryonic" EXACT []
2008 synonym: "activation of mitotic cell cycle, embryonic" NARROW []
2009 synonym: "stimulation of mitotic cell cycle, embryonic" NARROW []
2010 xref: GO:0045977
2011
2012 [Term]
2013 id: CCO:P0000212
2014 name: negative regulation of progression through preblastoderm mitotic cell cycle
2015 def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the preblastoderm mitotic cell cycle." [GOC:go_curators]
2016 is_a: CCO:P0000125 ! regulation of progression through preblastoderm mitotic cell cycle
2017 is_a: CCO:P0000210 ! negative regulation of progression through embryonic mitotic cell cycle
2018 synonym: "down regulation of progression through preblastoderm mitotic cell cycle" EXACT []
2019 synonym: "down-regulation of progression through preblastoderm mitotic cell cycle" EXACT []
2020 synonym: "downregulation of progression through preblastoderm mitotic cell cycle" EXACT []
2021 synonym: "negative regulation of preblastoderm mitotic cell cycle progression" EXACT []
2022 synonym: "inhibition of progression through preblastoderm mitotic cell cycle" NARROW []
2023 xref: GO:0046001
2024
2025 [Term]
2026 id: CCO:P0000213
2027 name: positive regulation of progression through preblastoderm mitotic cell cycle
2028 def: "Any process that activates or increases the frequency, rate or extent of progression through the preblastoderm mitotic cell cycle." [GOC:go_curators]
2029 is_a: CCO:P0000125 ! regulation of progression through preblastoderm mitotic cell cycle
2030 is_a: CCO:P0000211 ! positive regulation of mitotic cell cycle, embryonic
2031 synonym: "positive regulation of preblastoderm mitotic cell cycle progression" EXACT []
2032 synonym: "up regulation of progression through preblastoderm mitotic cell cycle" EXACT []
2033 synonym: "up-regulation of progression through preblastoderm mitotic cell cycle" EXACT []
2034 synonym: "upregulation of progression through preblastoderm mitotic cell cycle" EXACT []
2035 synonym: "activation of progression through preblastoderm mitotic cell cycle" NARROW []
2036 synonym: "stimulation of progression through preblastoderm mitotic cell cycle" NARROW []
2037 xref: GO:0046002
2038
2039 [Term]
2040 id: CCO:P0000214
2041 name: negative regulation of progression through syncytial blastoderm mitotic cell cycle
2042 def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the syncytial blastoderm mitotic cell cycle." [GOC:go_curators]
2043 is_a: CCO:P0000126 ! regulation of progression through syncytial blastoderm mitotic cell cycle
2044 is_a: CCO:P0000210 ! negative regulation of progression through embryonic mitotic cell cycle
2045 synonym: "down regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT []
2046 synonym: "down-regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT []
2047 synonym: "downregulation of progression through syncytial blastoderm mitotic cell cycle" EXACT []
2048 synonym: "negative regulation of syncytial blastoderm cell cycle progression" EXACT []
2049 synonym: "inhibition of progression through syncytial blastoderm mitotic cell cycle" NARROW []
2050 xref: GO:0046003
2051
2052 [Term]
2053 id: CCO:P0000215
2054 name: positive regulation of progression through syncytial blastoderm mitotic cell cycle
2055 def: "Any process that activates or increases the frequency, rate or extent of progression through the syncytial blastoderm mitotic cell cycle." [GOC:go_curators]
2056 is_a: CCO:P0000126 ! regulation of progression through syncytial blastoderm mitotic cell cycle
2057 is_a: CCO:P0000211 ! positive regulation of mitotic cell cycle, embryonic
2058 synonym: "positive regulation of syncytial blastoderm cell cycle progression" EXACT []
2059 synonym: "up regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT []
2060 synonym: "up-regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT []
2061 synonym: "upregulation of progression through syncytial blastoderm mitotic cell cycle" EXACT []
2062 synonym: "activation of progression through syncytial blastoderm mitotic cell cycle" NARROW []
2063 synonym: "stimulation of progression through syncytial blastoderm mitotic cell cycle" NARROW []
2064 xref: GO:0046004
2065
2066 [Term]
2067 id: CCO:P0000216
2068 name: regulation of transcription from RNA polymerase I promoter, mitotic
2069 def: "A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter during mitosis." [GOC:go_curators]
2070 is_a: CCO:P0000308 ! cell cycle process
2071 relationship: part_of CCO:P0000206 ! regulation of transcription, mitotic
2072 synonym: "mitotic regulation of transcription from Pol I promoter" EXACT []
2073 synonym: "regulation of transcription from Pol I promoter, mitotic" EXACT []
2074 xref: GO:0046017
2075
2076 [Term]
2077 id: CCO:P0000217
2078 name: positive regulation of transcription from RNA polymerase I promoter, mitotic
2079 def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter during mitosis." [GOC:go_curators]
2080 is_a: CCO:P0000207 ! positive regulation of transcription, mitotic
2081 is_a: CCO:P0000216 ! regulation of transcription from RNA polymerase I promoter, mitotic
2082 synonym: "mitotic activation of transcription from Pol I promoter" EXACT []
2083 synonym: "positive regulation of transcription from Pol I promoter, mitotic" EXACT []
2084 synonym: "up regulation of transcription from RNA polymerase I promoter, mitotic" EXACT []
2085 synonym: "up-regulation of transcription from RNA polymerase I promoter, mitotic" EXACT []
2086 synonym: "upregulation of transcription from RNA polymerase I promoter, mitotic" EXACT []
2087 synonym: "activation of transcription from RNA polymerase I promoter, mitotic" NARROW []
2088 synonym: "stimulation of transcription from RNA polymerase I promoter, mitotic" NARROW []
2089 xref: GO:0046018
2090
2091 [Term]
2092 id: CCO:P0000218
2093 name: regulation of transcription from RNA polymerase II promoter, mitotic
2094 def: "A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter during mitosis." [GOC:go_curators]
2095 is_a: CCO:P0000308 ! cell cycle process
2096 relationship: part_of CCO:P0000206 ! regulation of transcription, mitotic
2097 synonym: "mitotic regulation of transcription from Pol II promoter" EXACT []
2098 synonym: "regulation of transcription from Pol II promoter, mitotic" EXACT []
2099 xref: GO:0046021
2100
2101 [Term]
2102 id: CCO:P0000219
2103 name: positive regulation of transcription from RNA polymerase II promoter, mitotic
2104 def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter during mitosis." [GOC:go_curators]
2105 is_a: CCO:P0000207 ! positive regulation of transcription, mitotic
2106 is_a: CCO:P0000218 ! regulation of transcription from RNA polymerase II promoter, mitotic
2107 synonym: "mitotic activation of transcription from Pol II promoter" EXACT []
2108 synonym: "positive regulation of transcription from Pol II promoter, mitotic" EXACT []
2109 synonym: "up regulation of transcription from RNA polymerase II promoter, mitotic" EXACT []
2110 synonym: "up-regulation of transcription from RNA polymerase II promoter, mitotic" EXACT []
2111 synonym: "upregulation of transcription from RNA polymerase II promoter, mitotic" EXACT []
2112 synonym: "activation of transcription from RNA polymerase II promoter, mitotic" NARROW []
2113 synonym: "stimulation of transcription from RNA polymerase II promoter, mitotic" NARROW []
2114 xref: GO:0046022
2115
2116 [Term]
2117 id: CCO:P0000220
2118 name: regulation of transcription from RNA polymerase III promoter, mitotic
2119 def: "A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase III promoter during mitosis." [GOC:go_curators]
2120 is_a: CCO:P0000308 ! cell cycle process
2121 relationship: part_of CCO:P0000206 ! regulation of transcription, mitotic
2122 synonym: "mitotic regulation of transcription from Pol III promoter" EXACT []
2123 synonym: "regulation of transcription from Pol III promoter, mitotic" EXACT []
2124 xref: GO:0046023
2125
2126 [Term]
2127 id: CCO:P0000221
2128 name: positive regulation of transcription from RNA polymerase III promoter, mitotic
2129 def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III promoter during mitosis." [GOC:go_curators]
2130 is_a: CCO:P0000207 ! positive regulation of transcription, mitotic
2131 is_a: CCO:P0000220 ! regulation of transcription from RNA polymerase III promoter, mitotic
2132 synonym: "mitotic activation of transcription from Pol III promoter" EXACT []
2133 synonym: "positive regulation of transcription from Pol III promoter, mitotic" EXACT []
2134 synonym: "up regulation of transcription from RNA polymerase III promoter, mitotic" EXACT []
2135 synonym: "up-regulation of transcription from RNA polymerase III promoter, mitotic" EXACT []
2136 synonym: "upregulation of transcription from RNA polymerase III promoter, mitotic" EXACT []
2137 synonym: "activation of transcription from RNA polymerase III promoter, mitotic" NARROW []
2138 synonym: "stimulation of transcription from RNA polymerase III promoter, mitotic" NARROW []
2139 xref: GO:0046024
2140
2141 [Term]
2142 id: CCO:P0000222
2143 name: regulation of centriole replication
2144 def: "Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole." [GOC:ai]
2145 is_a: CCO:P0000228 ! regulation of centrosome cycle
2146 relationship: part_of CCO:P0000097 ! centriole replication
2147 xref: GO:0046599
2148
2149 [Term]
2150 id: CCO:P0000223
2151 name: negative regulation of centriole replication
2152 def: "Any process that stops, prevents or reduces the frequency, rate or extent of centriole replication." [GOC:ai]
2153 is_a: CCO:P0000222 ! regulation of centriole replication
2154 is_a: CCO:P0000229 ! negative regulation of centrosome cycle
2155 synonym: "down regulation of centriole replication" EXACT []
2156 synonym: "down-regulation of centriole replication" EXACT []
2157 synonym: "downregulation of centriole replication" EXACT []
2158 synonym: "inhibition of centriole replication" NARROW []
2159 xref: GO:0046600
2160
2161 [Term]
2162 id: CCO:P0000224
2163 name: positive regulation of centriole replication
2164 def: "Any process that activates or increases the frequency, rate or extent of centriole replication." [GOC:ai]
2165 is_a: CCO:P0000222 ! regulation of centriole replication
2166 is_a: CCO:P0000230 ! positive regulation of centrosome cycle
2167 synonym: "up regulation of centriole replication" EXACT []
2168 synonym: "up-regulation of centriole replication" EXACT []
2169 synonym: "upregulation of centriole replication" EXACT []
2170 synonym: "activation of centriole replication" NARROW []
2171 synonym: "stimulation of centriole replication" NARROW []
2172 xref: GO:0046601
2173
2174 [Term]
2175 id: CCO:P0000225
2176 name: regulation of mitotic centrosome separation
2177 def: "Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis." [GOC:ai]
2178 is_a: CCO:P0000228 ! regulation of centrosome cycle
2179 relationship: part_of CCO:P0000098 ! mitotic centrosome separation
2180 xref: GO:0046602
2181
2182 [Term]
2183 id: CCO:P0000226
2184 name: negative regulation of mitotic centrosome separation
2185 def: "Any process that stops, prevents or reduces the frequency, rate or extent of centrosome separation." [GOC:ai]
2186 is_a: CCO:P0000225 ! regulation of mitotic centrosome separation
2187 is_a: CCO:P0000229 ! negative regulation of centrosome cycle
2188 synonym: "down regulation of mitotic centrosome separation" EXACT []
2189 synonym: "down-regulation of mitotic centrosome separation" EXACT []
2190 synonym: "downregulation of mitotic centrosome separation" EXACT []
2191 synonym: "inhibition of mitotic centrosome separation" NARROW []
2192 xref: GO:0046603
2193
2194 [Term]
2195 id: CCO:P0000227
2196 name: positive regulation of mitotic centrosome separation
2197 def: "Any process that activates or increases the frequency, rate or extent of centrosome separation." [GOC:ai]
2198 is_a: CCO:P0000225 ! regulation of mitotic centrosome separation
2199 is_a: CCO:P0000230 ! positive regulation of centrosome cycle
2200 synonym: "up regulation of mitotic centrosome separation" EXACT []
2201 synonym: "up-regulation of mitotic centrosome separation" EXACT []
2202 synonym: "upregulation of mitotic centrosome separation" EXACT []
2203 synonym: "activation of mitotic centrosome separation" NARROW []
2204 synonym: "stimulation of mitotic centrosome separation" NARROW []
2205 xref: GO:0046604
2206
2207 [Term]
2208 id: CCO:P0000228
2209 name: regulation of centrosome cycle
2210 def: "Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation." [GOC:ai]
2211 relationship: part_of CCO:P0000096 ! centrosome cycle
2212 xref: GO:0046605
2213
2214 [Term]
2215 id: CCO:P0000229
2216 name: negative regulation of centrosome cycle
2217 def: "Any process that stops, prevents or reduces the frequency, rate or extent of the centrosome cycle." [GOC:ai]
2218 is_a: CCO:P0000228 ! regulation of centrosome cycle
2219 synonym: "down regulation of centrosome cycle" EXACT []
2220 synonym: "down-regulation of centrosome cycle" EXACT []
2221 synonym: "downregulation of centrosome cycle" EXACT []
2222 synonym: "inhibition of centrosome cycle" NARROW []
2223 xref: GO:0046606
2224
2225 [Term]
2226 id: CCO:P0000230
2227 name: positive regulation of centrosome cycle
2228 def: "Any process that activates or increases the frequency, rate or extent of the centrosome cycle." [GOC:ai]
2229 is_a: CCO:P0000228 ! regulation of centrosome cycle
2230 synonym: "up regulation of centrosome cycle" EXACT []
2231 synonym: "up-regulation of centrosome cycle" EXACT []
2232 synonym: "upregulation of centrosome cycle" EXACT []
2233 synonym: "activation of centrosome cycle" NARROW []
2234 synonym: "stimulation of centrosome cycle" NARROW []
2235 xref: GO:0046607
2236
2237 [Term]
2238 id: CCO:P0000231
2239 name: suppression by virus of host cell cycle arrest
2240 def: "Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur." [PMID:9371605]
2241 is_a: CCO:P0000137 ! modification by virus of host cell cycle regulation
2242 synonym: "negative regulation by virus of cell cycle arrest" EXACT []
2243 synonym: "viral inhibition of cell cycle arrest" EXACT []
2244 xref: GO:0046792
2245
2246 [Term]
2247 id: CCO:P0000232
2248 name: replication fork protection
2249 def: "Processes preventing the collapse of stalled replication forks." [GOC:vw, PMID:14560029]
2250 relationship: part_of CCO:P0000160 ! intra-S DNA damage checkpoint
2251 synonym: "replication fork maintenance" BROAD []
2252 synonym: "replication fork stabilization" BROAD []
2253 xref: GO:0048478
2254
2255 [Term]
2256 id: CCO:P0000233
2257 name: chiasma formation
2258 def: "The cell cycle process whereby a connection between chromatids forms, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids." [http:www.onelook.com]
2259 is_a: CCO:P0000308 ! cell cycle process
2260 relationship: part_of CCO:P0000106 ! synapsis
2261 xref: GO:0051026
2262
2263 [Term]
2264 id: CCO:P0000234
2265 name: regulation of transcription, meiotic
2266 def: "Any process that modulates the frequency, rate or extent of transcription during meiosis." [GOC:go_curators]
2267 relationship: part_of CCO:P0000103 ! meiosis
2268 synonym: "meiotic regulation of transcription" EXACT []
2269 xref: GO:0051037
2270
2271 [Term]
2272 id: CCO:P0000235
2273 name: negative regulation of transcription, meiotic
2274 def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription during meiosis." [GOC:ai]
2275 is_a: CCO:P0000234 ! regulation of transcription, meiotic
2276 synonym: "down regulation of transcription, meiotic" EXACT []
2277 synonym: "down-regulation of transcription, meiotic" EXACT []
2278 synonym: "downregulation of transcription, meiotic" EXACT []
2279 synonym: "meiotic repression of transcription" EXACT []
2280 synonym: "negative regulation of meiotic transcription" EXACT []
2281 synonym: "inhibition of transcription, meiotic" NARROW []
2282 xref: GO:0051038
2283
2284 [Term]
2285 id: CCO:P0000236
2286 name: positive regulation of transcription, meiotic
2287 def: "Any process that activates or increases the frequency, rate or extent of transcription during meiosis." [GOC:ai]
2288 is_a: CCO:P0000234 ! regulation of transcription, meiotic
2289 synonym: "positive regulation of meiotic transcription" EXACT []
2290 synonym: "up regulation of transcription, meiotic" EXACT []
2291 synonym: "up-regulation of transcription, meiotic" EXACT []
2292 synonym: "upregulation of transcription, meiotic" EXACT []
2293 synonym: "activation of transcription, meiotic" NARROW []
2294 synonym: "stimulation of transcription, meiotic" NARROW []
2295 xref: GO:0051039
2296
2297 [Term]
2298 id: CCO:P0000237
2299 name: meiotic nuclear envelope disassembly
2300 def: "The cell cycle process whereby the controlled breakdown of the nuclear envelope during meiotic cell division occurs." [GOC:bf]
2301 is_a: CCO:P0000308 ! cell cycle process
2302 relationship: part_of CCO:P0000265 ! meiotic cell cycle
2303 synonym: "meiotic nuclear envelope breakdown" EXACT []
2304 synonym: "meiotic nuclear envelope catabolism" EXACT []
2305 synonym: "meiotic nuclear envelope degradation" EXACT []
2306 xref: GO:0051078
2307
2308 [Term]
2309 id: CCO:P0000238
2310 name: meiosis I nuclear envelope disassembly
2311 def: "The controlled breakdown of the nuclear envelope during the first division of meiosis." [GOC:bf]
2312 is_a: CCO:P0000237 ! meiotic nuclear envelope disassembly
2313 relationship: part_of CCO:P0000104 ! meiosis I
2314 synonym: "meiosis I nuclear envelope breakdown" EXACT []
2315 synonym: "meiosis I nuclear envelope catabolism" EXACT []
2316 synonym: "meiosis I nuclear envelope degradation" EXACT []
2317 xref: GO:0051079
2318
2319 [Term]
2320 id: CCO:P0000239
2321 name: meiosis II nuclear envelope disassembly
2322 def: "The controlled breakdown of the nuclear envelope during the second division of meiosis." [GOC:bf]
2323 is_a: CCO:P0000237 ! meiotic nuclear envelope disassembly
2324 relationship: part_of CCO:P0000112 ! meiosis II
2325 synonym: "meiosis II nuclear envelope breakdown" EXACT []
2326 synonym: "meiosis II nuclear envelope catabolism" EXACT []
2327 synonym: "meiosis II nuclear envelope degradation" EXACT []
2328 xref: GO:0051080
2329
2330 [Term]
2331 id: CCO:P0000240
2332 name: meiotic sister chromatid cohesion
2333 def: "The cell cycle process whereby sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis." [GOC:ai]
2334 is_a: CCO:P0000308 ! cell cycle process
2335 relationship: part_of CCO:P0000104 ! meiosis I
2336 relationship: part_of CCO:P0000189 ! meiotic chromosome segregation
2337 xref: GO:0051177
2338
2339 [Term]
2340 id: CCO:P0000241
2341 name: meiotic chromosome decondensation
2342 def: "The cell cycle process whereby chromosome structure is altered from the condensed form held during meiosis to the relaxed dispersed form held in resting cells." [GOC:ai]
2343 is_a: CCO:P0000308 ! cell cycle process
2344 relationship: part_of CCO:P0000189 ! meiotic chromosome segregation
2345 xref: GO:0051178
2346
2347 [Term]
2348 id: CCO:P0000242
2349 name: meiotic spindle assembly
2350 def: "The formation of the spindle during a meiotic cell cycle." [GOC:ai]
2351 is_a: CCO:P0000029 ! meiotic spindle organization and biogenesis
2352 synonym: "meiotic spindle biogenesis" EXACT []
2353 synonym: "meiotic spindle biosynthesis" EXACT []
2354 synonym: "meiotic spindle formation" EXACT []
2355 synonym: "spindle assembly during meiosis" EXACT []
2356 synonym: "spindle biogenesis during meiosis" EXACT []
2357 synonym: "spindle formation during meiosis" EXACT []
2358 synonym: "bipolar spindle biosynthesis" BROAD []
2359 synonym: "bipolar spindle formation" BROAD []
2360 xref: GO:0051226
2361
2362 [Term]
2363 id: CCO:P0000243
2364 name: mitotic spindle assembly
2365 def: "The formation of the spindle during a mitotic cell cycle." [GOC:ai]
2366 is_a: CCO:P0000058 ! mitotic spindle organization and biogenesis
2367 synonym: "mitotic spindle biogenesis" EXACT []
2368 synonym: "mitotic spindle biosynthesis" EXACT []
2369 synonym: "mitotic spindle formation" EXACT []
2370 synonym: "spindle assembly during mitosis" EXACT []
2371 synonym: "spindle biogenesis during mitosis" EXACT []
2372 synonym: "spindle formation during mitosis" EXACT []
2373 xref: GO:0051227
2374
2375 [Term]
2376 id: CCO:P0000244
2377 name: mitotic spindle disassembly
2378 def: "The controlled breakdown of the spindle during a mitotic cell cycle." [GOC:ai]
2379 is_a: CCO:P0000058 ! mitotic spindle organization and biogenesis
2380 synonym: "mitotic spindle breakdown" EXACT []
2381 synonym: "mitotic spindle catabolism" EXACT []
2382 synonym: "mitotic spindle degradation" EXACT []
2383 synonym: "spindle breakdown during mitosis" EXACT []
2384 synonym: "spindle degradation during mitosis" EXACT []
2385 synonym: "spindle disassembly during mitosis" EXACT []
2386 xref: GO:0051228
2387
2388 [Term]
2389 id: CCO:P0000245
2390 name: meiotic spindle disassembly
2391 def: "The controlled breakdown of the spindle during a meiotic cell cycle." [GOC:ai]
2392 is_a: CCO:P0000029 ! meiotic spindle organization and biogenesis
2393 synonym: "meiotic spindle breakdown" EXACT []
2394 synonym: "meiotic spindle catabolism" EXACT []
2395 synonym: "meiotic spindle degradation" EXACT []
2396 synonym: "spindle breakdown during meiosis" EXACT []
2397 synonym: "spindle degradation during meiosis" EXACT []
2398 synonym: "spindle disassembly during meiosis" EXACT []
2399 xref: GO:0051229
2400
2401 [Term]
2402 id: CCO:P0000246
2403 name: meiotic spindle elongation
2404 def: "The lengthening of the distance between poles of the spindle during a meiotic cell cycle." [GOC:ai]
2405 is_a: CCO:P0000310 ! spindle elongation
2406 relationship: part_of CCO:P0000029 ! meiotic spindle organization and biogenesis
2407 synonym: "spindle elongation during meiosis" EXACT []
2408 xref: GO:0051232
2409
2410 [Term]
2411 id: CCO:P0000247
2412 name: mitotic spindle midzone assembly
2413 def: "The formation of the mitotic spindle midzone, the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap." [GOC:ai]
2414 is_a: CCO:P0000311 ! spindle midzone assembly
2415 relationship: part_of CCO:P0000243 ! mitotic spindle assembly
2416 synonym: "mitotic spindle midzone biogenesis" EXACT []
2417 synonym: "mitotic spindle midzone biosynthesis" EXACT []
2418 synonym: "mitotic spindle midzone formation" EXACT []
2419 synonym: "spindle midzone assembly during mitosis" EXACT []
2420 synonym: "spindle midzone biogenesis during mitosis" EXACT []
2421 synonym: "spindle midzone formation during mitosis" EXACT []
2422 xref: GO:0051256
2423
2424 [Term]
2425 id: CCO:P0000248
2426 name: meiotic spindle midzone assembly
2427 def: "The formation of the meiotic spindle midzone, the area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap." [GOC:ai]
2428 is_a: CCO:P0000311 ! spindle midzone assembly
2429 relationship: part_of CCO:P0000242 ! meiotic spindle assembly
2430 synonym: "meiotic spindle midzone biogenesis" EXACT []
2431 synonym: "meiotic spindle midzone biosynthesis" EXACT []
2432 synonym: "meiotic spindle midzone formation" EXACT []
2433 synonym: "spindle midzone assembly during meiosis" EXACT []
2434 synonym: "spindle midzone biogenesis during meiosis" EXACT []
2435 synonym: "spindle midzone formation during meiosis" EXACT []
2436 xref: GO:0051257
2437
2438 [Term]
2439 id: CCO:P0000249
2440 name: establishment of meiotic spindle localization
2441 def: "The cell cycle process whereby the directed movement of the meiotic spindle to a specific location in the cell occurs." [GOC:ai]
2442 is_a: CCO:P0000308 ! cell cycle process
2443 relationship: part_of CCO:P0000265 ! meiotic cell cycle
2444 synonym: "meiotic spindle positioning" EXACT []
2445 synonym: "spindle positioning during meiosis" EXACT []
2446 xref: GO:0051295
2447
2448 [Term]
2449 id: CCO:P0000250
2450 name: establishment of meiotic spindle orientation
2451 def: "The processes that set the alignment of meiotic spindle relative to other cellular structures." [GOC:ai]
2452 is_a: CCO:P0000249 ! establishment of meiotic spindle localization
2453 synonym: "establishment of spindle orientation during meiosis" EXACT []
2454 synonym: "meiotic spindle orientation" EXACT []
2455 synonym: "orienting of meiotic spindle" EXACT []
2456 xref: GO:0051296
2457
2458 [Term]
2459 id: CCO:P0000251
2460 name: centrosome duplication
2461 def: "The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized." [GOC:ai]
2462 relationship: part_of CCO:P0000096 ! centrosome cycle
2463 synonym: "centrosome replication" EXACT []
2464 xref: GO:0051298
2465
2466 [Term]
2467 id: CCO:P0000252
2468 name: centrosome separation
2469 def: "The process by which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle." [GOC:ai]
2470 relationship: part_of CCO:P0000096 ! centrosome cycle
2471 xref: GO:0051299
2472
2473 [Term]
2474 id: CCO:P0000253
2475 name: mitotic sister chromatid separation
2476 def: "The process by which sister chromatids are physically detached from each other during mitosis." [GOC:ai]
2477 is_a: CCO:P0000312 ! chromosome separation
2478 relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation
2479 synonym: "chromosome separation during mitosis" RELATED []
2480 synonym: "mitotic chromosome separation" RELATED []
2481 synonym: "sister chromatid separation during mitosis" EXACT []
2482 xref: GO:0051306
2483
2484 [Term]
2485 id: CCO:P0000254
2486 name: meiotic chromosome separation
2487 def: "The process by which chromosomes are physically detached from each other during meiosis." [GOC:ai]
2488 is_a: CCO:P0000312 ! chromosome separation
2489 relationship: part_of CCO:P0000189 ! meiotic chromosome segregation
2490 synonym: "chromosome separation during meiosis" EXACT []
2491 xref: GO:0051307
2492
2493 [Term]
2494 id: CCO:P0000255
2495 name: male meiosis chromosome separation
2496 def: "The process by which paired chromosomes are physically detached from each other during male meiosis." [GOC:ai]
2497 is_a: CCO:P0000065 ! male meiosis chromosome segregation
2498 is_a: CCO:P0000254 ! meiotic chromosome separation
2499 synonym: "chromosome separation during male meiosis" EXACT []
2500 xref: GO:0051308
2501
2502 [Term]
2503 id: CCO:P0000256
2504 name: female meiosis chromosome separation
2505 def: "The process by which paired chromosomes are physically detached from each other during female meiosis." [GOC:ai]
2506 is_a: CCO:P0000132 ! female meiosis chromosome segregation
2507 is_a: CCO:P0000254 ! meiotic chromosome separation
2508 synonym: "chromosome separation during female meiosis" EXACT []
2509 xref: GO:0051309
2510
2511 [Term]
2512 id: CCO:P0000257
2513 name: meiotic metaphase plate congression
2514 def: "The cell cycle process whereby chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis." [GOC:ai]
2515 is_a: CCO:P0000308 ! cell cycle process
2516 relationship: part_of CCO:P0000189 ! meiotic chromosome segregation
2517 synonym: "metaphase plate congression during meiosis" EXACT []
2518 xref: GO:0051311
2519
2520 [Term]
2521 id: CCO:P0000258
2522 name: attachment of spindle microtubules to mitotic chromosome
2523 def: "The cell cycle process whereby spindle microtubules become physically associated with a chromosome during mitosis." [GOC:ai]
2524 is_a: CCO:P0000308 ! cell cycle process
2525 relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation
2526 xref: GO:0051314
2527
2528 [Term]
2529 id: CCO:P0000259
2530 name: attachment of spindle microtubules to kinetochore during mitosis
2531 def: "The cell cycle process whereby spindle microtubules become physically associated with the proteins making up the kinetochore complex during mitosis. During mitosis, the kinetochores of sister chromosomes are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs." [GOC:ai, GOC:clt]
2532 is_a: CCO:P0000308 ! cell cycle process
2533 relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation
2534 xref: GO:0051315
2535
2536 [Term]
2537 id: CCO:P0000260
2538 name: attachment of spindle microtubules to kinetochore during meiotic chromosome segregation
2539 def: "The cell cycle process whereby spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiotic chromosome segregation." [GOC:ai]
2540 is_a: CCO:P0000308 ! cell cycle process
2541 relationship: part_of CCO:P0000189 ! meiotic chromosome segregation
2542 synonym: "attachment of spindle microtubules to kinetochore during meiosis" RELATED []
2543 xref: GO:0051316
2544
2545 [Term]
2546 id: CCO:P0000261
2547 name: attachment of spindle microtubules to meiotic chromosome
2548 def: "The cell cycle process whereby spindle microtubules become physically associated with a chromosome during meiosis." [GOC:ai]
2549 is_a: CCO:P0000308 ! cell cycle process
2550 relationship: part_of CCO:P0000189 ! meiotic chromosome segregation
2551 xref: GO:0051317
2552
2553 [Term]
2554 id: CCO:P0000262
2555 name: G1 phase
2556 def: "Progression through G1 phase, one of two 'gap' phases in the cell cycle; G1 is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis." [GOC:ai]
2557 is_a: CCO:P0000309 ! cell cycle phase
2558 relationship: part_of CCO:P0000269 ! interphase
2559 xref: GO:0051318
2560
2561 [Term]
2562 id: CCO:P0000263
2563 name: G2 phase
2564 def: "Progression through G2 phase, one of two 'gap' phases in the cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis)." [GOC:ai]
2565 is_a: CCO:P0000309 ! cell cycle phase
2566 relationship: part_of CCO:P0000269 ! interphase
2567 xref: GO:0051319
2568
2569 [Term]
2570 id: CCO:P0000264
2571 name: S phase
2572 def: "Progression through S phase, the part of the cell cycle during which DNA synthesis takes place." [GOC:ai]
2573 is_a: CCO:P0000309 ! cell cycle phase
2574 relationship: part_of CCO:P0000269 ! interphase
2575 xref: GO:0051320
2576
2577 [Term]
2578 id: CCO:P0000265
2579 name: meiotic cell cycle
2580 def: "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell." [GOC:ai]
2581 is_a: CCO:P0000056 ! cell cycle
2582 xref: GO:0051321
2583
2584 [Term]
2585 id: CCO:P0000266
2586 name: anaphase
2587 def: "Progression through anaphase, the third stage of chromosome segregation in the cell cycle. Canonically, sister chromatids (or homologous chromosomes) separate and migrate towards the poles of the spindle." [http:www.onelook.com]
2588 is_a: CCO:P0000309 ! cell cycle phase
2589 relationship: part_of CCO:P0000038 ! M phase
2590 xref: GO:0051322
2591
2592 [Term]
2593 id: CCO:P0000267
2594 name: metaphase
2595 def: "Progression through metaphase, the second stage of chromosome segregation in the cell cycle. Canonically, chromosomes become aligned on the equatorial plate of the cell." [http:www.onelook.com]
2596 is_a: CCO:P0000309 ! cell cycle phase
2597 relationship: part_of CCO:P0000038 ! M phase
2598 xref: GO:0051323
2599
2600 [Term]
2601 id: CCO:P0000268
2602 name: prophase
2603 def: "Progression through prophase, the first stage of chromosome segregation in the cell cycle. Canonically, chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell." [GOC:ai]
2604 is_a: CCO:P0000309 ! cell cycle phase
2605 relationship: part_of CCO:P0000038 ! M phase
2606 xref: GO:0051324
2607
2608 [Term]
2609 id: CCO:P0000269
2610 name: interphase
2611 def: "Progression through interphase, the stage of cell cycle between successive rounds of chromosome segregation. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs." [http:www.onelook.com]
2612 is_a: CCO:P0000309 ! cell cycle phase
2613 synonym: "karyostasis" EXACT []
2614 synonym: "resting phase" BROAD []
2615 xref: GO:0051325
2616
2617 [Term]
2618 id: CCO:P0000270
2619 name: telophase
2620 def: "Progression through telophase, the last stage of chromosome segregation in the cell cycle. Canonically, telophase begins when the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [http:www.onelook.com]
2621 is_a: CCO:P0000309 ! cell cycle phase
2622 relationship: part_of CCO:P0000038 ! M phase
2623 xref: GO:0051326
2624
2625 [Term]
2626 id: CCO:P0000271
2627 name: M phase of meiotic cell cycle
2628 def: "Progression through M phase, the part of the meiotic cell cycle during which meiosis and cytokinesis take place." [GOC:ai]
2629 is_a: CCO:P0000038 ! M phase
2630 relationship: part_of CCO:P0000265 ! meiotic cell cycle
2631 xref: GO:0051327
2632
2633 [Term]
2634 id: CCO:P0000272
2635 name: interphase of meiotic cell cycle
2636 def: "Progression through interphase, the stage of cell cycle between successive rounds of meiosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs." [GOC:ai]
2637 is_a: CCO:P0000269 ! interphase
2638 relationship: part_of CCO:P0000265 ! meiotic cell cycle
2639 xref: GO:0051328
2640
2641 [Term]
2642 id: CCO:P0000273
2643 name: interphase of mitotic cell cycle
2644 def: "Progression through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs." [GOC:ai]
2645 is_a: CCO:P0000269 ! interphase
2646 relationship: part_of CCO:P0000037 ! mitotic cell cycle
2647 xref: GO:0051329
2648
2649 [Term]
2650 id: CCO:P0000274
2651 name: G1 phase of meiotic cell cycle
2652 def: "Progression through G1 phase, one of two 'gap' phases in the meiotic cell cycle; G1 is the interval between the completion of meiosis and the beginning of DNA synthesis." [GOC:ai]
2653 is_a: CCO:P0000262 ! G1 phase
2654 relationship: part_of CCO:P0000272 ! interphase of meiotic cell cycle
2655 xref: GO:0051330
2656
2657 [Term]
2658 id: CCO:P0000275
2659 name: G2 phase of meiotic cell cycle
2660 def: "Progression through G2 phase, one of two 'gap' phases in the meiotic cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of meiosis." [GOC:ai]
2661 is_a: CCO:P0000263 ! G2 phase
2662 relationship: part_of CCO:P0000272 ! interphase of meiotic cell cycle
2663 xref: GO:0051331
2664
2665 [Term]
2666 id: CCO:P0000276
2667 name: S phase of meiotic cell cycle
2668 def: "Progression through S phase, the part of the meiotic cell cycle during which DNA synthesis takes place." [GOC:ai]
2669 is_a: CCO:P0000264 ! S phase
2670 relationship: part_of CCO:P0000272 ! interphase of meiotic cell cycle
2671 xref: GO:0051332
2672
2673 [Term]
2674 id: CCO:P0000277
2675 name: meiotic nuclear envelope reassembly
2676 def: "The cell cycle process whereby the reformation of the nuclear envelope during meiosis occurs." [GOC:ai]
2677 is_a: CCO:P0000308 ! cell cycle process
2678 relationship: part_of CCO:P0000265 ! meiotic cell cycle
2679 xref: GO:0051333
2680
2681 [Term]
2682 id: CCO:P0000278
2683 name: meiosis I nuclear envelope reassembly
2684 def: "The reformation of the nuclear envelope during meiosis I." [GOC:ai]
2685 is_a: CCO:P0000277 ! meiotic nuclear envelope reassembly
2686 relationship: part_of CCO:P0000104 ! meiosis I
2687 xref: GO:0051334
2688
2689 [Term]
2690 id: CCO:P0000279
2691 name: meiosis II nuclear envelope reassembly
2692 def: "The reformation of the nuclear envelope during meiosis II." [GOC:ai]
2693 is_a: CCO:P0000277 ! meiotic nuclear envelope reassembly
2694 relationship: part_of CCO:P0000112 ! meiosis II
2695 xref: GO:0051335
2696
2697 [Term]
2698 id: CCO:P0000280
2699 name: interphase microtubule nucleation by interphase microtubule organizing center
2700 def: "The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation." [GOC:ai]
2701 relationship: part_of CCO:P0000269 ! interphase
2702 synonym: "IMTOC-mediated microtubule nucleation during interphase" EXACT []
2703 synonym: "interphase microtubule nucleation by interphase microtubule organising centre" EXACT []
2704 synonym: "interphase microtubule organizing center-mediated microtubule nucleation during interphase" EXACT []
2705 synonym: "microtubule nucleation during interphase by IMTOC" EXACT []
2706 synonym: "microtubule nucleation during interphase by interphase microtubule organizing center" EXACT []
2707 xref: GO:0051415
2708
2709 [Term]
2710 id: CCO:P0000281
2711 name: negative regulation of ubiquitin ligase activity during mitotic cell cycle
2712 def: "Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity during the mitotic cell cycle." [GOC:ai]
2713 is_a: CCO:P0000283 ! regulation of ubiquitin ligase activity during mitotic cell cycle
2714 synonym: "down regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT []
2715 synonym: "down-regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT []
2716 synonym: "downregulation of ubiquitin ligase activity during mitotic cell cycle" EXACT []
2717 synonym: "anaphase promoting complex inhibition during mitotic cell cycle" NARROW []
2718 synonym: "anaphase-promoting complex inhibition during mitotic cell cycle" NARROW []
2719 synonym: "APC inhibition during mitotic cell cycle" NARROW []
2720 synonym: "inhibition of ubiquitin ligase activity during mitotic cell cycle" NARROW []
2721 synonym: "mitotic anaphase promoting complex inhibition" NARROW []
2722 synonym: "mitotic anaphase promoting complex inhibitor" NARROW []
2723 synonym: "mitotic anaphase-promoting complex inhibition" NARROW []
2724 synonym: "mitotic anaphase-promoting complex inhibitor" NARROW []
2725 synonym: "mitotic APC inhibition" NARROW []
2726 synonym: "mitotic APC inhibitor" NARROW []
2727 synonym: "mitotic SCF complex inhibitor" NARROW []
2728 synonym: "mitotic ubiquitin ligase inhibitor" NARROW []
2729 xref: GO:0051436
2730
2731 [Term]
2732 id: CCO:P0000282
2733 name: positive regulation of ubiquitin ligase activity during mitotic cell cycle
2734 def: "Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the mitotic cell cycle." [GOC:ai]
2735 is_a: CCO:P0000283 ! regulation of ubiquitin ligase activity during mitotic cell cycle
2736 synonym: "up regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT []
2737 synonym: "up-regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT []
2738 synonym: "upregulation of ubiquitin ligase activity during mitotic cell cycle" EXACT []
2739 synonym: "activation of ubiquitin ligase activity during mitotic cell cycle" NARROW []
2740 synonym: "mitotic SCF complex activator" NARROW []
2741 synonym: "mitotic ubiquitin ligase activator" NARROW []
2742 synonym: "stimulation of ubiquitin ligase activity during mitotic cell cycle" NARROW []
2743 xref: GO:0051437
2744
2745 [Term]
2746 id: CCO:P0000283
2747 name: regulation of ubiquitin ligase activity during mitotic cell cycle
2748 def: "A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the mitotic cell cycle." [GOC:ai]
2749 is_a: CCO:P0000308 ! cell cycle process
2750 relationship: part_of CCO:P0000037 ! mitotic cell cycle
2751 synonym: "mitotic ubiquitin ligase regulator" RELATED []
2752 synonym: "mitotic ubiquitin-protein ligase regulator" RELATED []
2753 synonym: "regulation of ubiquitin-protein ligase activity during mitotic cell cycle" EXACT []
2754 synonym: "mitotic anaphase-promoting complex regulator" NARROW []
2755 synonym: "mitotic APC regulator" NARROW []
2756 synonym: "mitotic SCF complex regulator" NARROW []
2757 xref: GO:0051439
2758
2759 [Term]
2760 id: CCO:P0000284
2761 name: regulation of ubiquitin ligase activity during meiotic cell cycle
2762 def: "A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle." [EC:6.3.2.19, GOC:ai]
2763 is_a: CCO:P0000308 ! cell cycle process
2764 relationship: part_of CCO:P0000265 ! meiotic cell cycle
2765 synonym: "meiotic ubiquitin ligase regulator" RELATED []
2766 synonym: "meiotic ubiquitin-protein ligase regulator" RELATED []
2767 synonym: "regulation of ubiquitin-protein ligase activity during meiotic cell cycle" EXACT []
2768 synonym: "meiotic anaphase-promoting complex regulator" NARROW []
2769 synonym: "meiotic APC regulator" NARROW []
2770 synonym: "meiotic SCF complex regulator" NARROW []
2771 xref: GO:0051440
2772
2773 [Term]
2774 id: CCO:P0000285
2775 name: positive regulation of ubiquitin ligase activity during meiotic cell cycle
2776 def: "Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the meiotic cell cycle." [GOC:ai]
2777 is_a: CCO:P0000284 ! regulation of ubiquitin ligase activity during meiotic cell cycle
2778 synonym: "up regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT []
2779 synonym: "up-regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT []
2780 synonym: "upregulation of ubiquitin ligase activity during meiotic cell cycle" EXACT []
2781 synonym: "activation of ubiquitin ligase activity during meiotic cell cycle" NARROW []
2782 synonym: "meiotic SCF complex activator" NARROW []
2783 synonym: "meiotic ubiquitin ligase activator" NARROW []
2784 synonym: "stimulation of ubiquitin ligase activity during meiotic cell cycle" NARROW []
2785 xref: GO:0051441
2786
2787 [Term]
2788 id: CCO:P0000286
2789 name: negative regulation of ubiquitin ligase activity during meiotic cell cycle
2790 def: "Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle." [GOC:ai]
2791 is_a: CCO:P0000284 ! regulation of ubiquitin ligase activity during meiotic cell cycle
2792 synonym: "down regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT []
2793 synonym: "down-regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT []
2794 synonym: "downregulation of ubiquitin ligase activity during meiotic cell cycle" EXACT []
2795 synonym: "anaphase promoting complex inhibition during meiotic cell cycle" NARROW []
2796 synonym: "anaphase-promoting complex inhibition during meiotic cell cycle" NARROW []
2797 synonym: "APC inhibition during meiotic cell cycle" NARROW []
2798 synonym: "inhibition of ubiquitin ligase activity during meiotic cell cycle" NARROW []
2799 synonym: "meiotic anaphase promoting complex inhibition" NARROW []
2800 synonym: "meiotic anaphase promoting complex inhibitor" NARROW []
2801 synonym: "meiotic anaphase-promoting complex inhibition" NARROW []
2802 synonym: "meiotic anaphase-promoting complex inhibitor" NARROW []
2803 synonym: "meiotic APC inhibition" NARROW []
2804 synonym: "meiotic APC inhibitor" NARROW []
2805 synonym: "meiotic SCF complex inhibitor" NARROW []
2806 synonym: "meiotic ubiquitin ligase inhibitor" NARROW []
2807 xref: GO:0051442
2808
2809 [Term]
2810 id: CCO:P0000287
2811 name: regulation of progression through meiotic cell cycle
2812 def: "Any process that modulates the rate or extent of progression through the mitotic cell cycle." [GOC:ai]
2813 is_a: CCO:P0000004 ! regulation of progression through cell cycle
2814 relationship: part_of CCO:P0000265 ! meiotic cell cycle
2815 synonym: "meiotic cell cycle regulator" RELATED []
2816 synonym: "control of meiotic cell cycle progression" EXACT []
2817 synonym: "meiotic cell cycle control" EXACT []
2818 synonym: "meiotic cell cycle modulation" EXACT []
2819 synonym: "meiotic cell cycle regulation" EXACT []
2820 synonym: "modulation of meiotic cell cycle progression" EXACT []
2821 synonym: "regulation of meiotic cell cycle" EXACT []
2822 synonym: "regulation of meiotic cell cycle progression" EXACT []
2823 xref: GO:0051445
2824
2825 [Term]
2826 id: CCO:P0000288
2827 name: positive regulation of progression through meiotic cell cycle
2828 def: "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai]
2829 is_a: CCO:P0000199 ! positive regulation of progression through cell cycle
2830 is_a: CCO:P0000287 ! regulation of progression through meiotic cell cycle
2831 synonym: "positive regulation of meiotic cell cycle progression" EXACT []
2832 synonym: "up regulation of progression through meiotic cell cycle" EXACT []
2833 synonym: "up-regulation of progression through meiotic cell cycle" EXACT []
2834 synonym: "upregulation of progression through meiotic cell cycle" EXACT []
2835 synonym: "activation of progression through meiotic cell cycle" NARROW []
2836 synonym: "stimulation of progression through meiotic cell cycle" NARROW []
2837 xref: GO:0051446
2838
2839 [Term]
2840 id: CCO:P0000289
2841 name: negative regulation of progression through meiotic cell cycle
2842 def: "Any process that stops, prevents or reduces the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai]
2843 is_a: CCO:P0000198 ! negative regulation of progression through cell cycle
2844 is_a: CCO:P0000287 ! regulation of progression through meiotic cell cycle
2845 synonym: "down regulation of progression through meiotic cell cycle" EXACT []
2846 synonym: "down-regulation of progression through meiotic cell cycle" EXACT []
2847 synonym: "downregulation of progression through meiotic cell cycle" EXACT []
2848 synonym: "negative regulation of meiotic cell cycle progression" EXACT []
2849 synonym: "inhibition of progression through meiotic cell cycle" NARROW []
2850 xref: GO:0051447
2851
2852 [Term]
2853 id: CCO:P0000290
2854 name: attachment of spindle microtubules to kinetochore during meiosis I
2855 def: "The process by which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs." [GOC:ai, GOC:clt]
2856 is_a: CCO:P0000260 ! attachment of spindle microtubules to kinetochore during meiotic chromosome segregation
2857 relationship: part_of CCO:P0000191 ! homologous chromosome segregation
2858 synonym: "monopolar attachment" EXACT []
2859 synonym: "sister kinetochore monoorientation" EXACT []
2860 comment: Note that the synonym 'monopolar attachment' refers to the normal attachment of sister chromosomes to the spindle in meiosis I, and not to the aberrant attachment of sister kinetochores to a single pole in mitosis.
2861 xref: GO:0051455
2862
2863 [Term]
2864 id: CCO:P0000291
2865 name: attachment of spindle microtubules to kinetochore during meiosis II
2866 def: "The process by which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs." [GOC:ai, GOC:clt]
2867 is_a: CCO:P0000260 ! attachment of spindle microtubules to kinetochore during meiotic chromosome segregation
2868 relationship: part_of CCO:P0000192 ! meiotic sister chromatid segregation
2869 xref: GO:0051456
2870
2871 [Term]
2872 id: CCO:P0000292
2873 name: anaphase-promoting complex activation during meiotic cell cycle
2874 def: "Any process that initiatiates the ubiquitin ligase activity of the anaphase-promoting complex during the meiotic cell cycle." [GOC:mah, PMID:10871297]
2875 is_a: CCO:P0000285 ! positive regulation of ubiquitin ligase activity during meiotic cell cycle
2876 synonym: "activation of ubiquitin ligase activity of anaphase promoting complex during meiotic cell cycle" EXACT []
2877 synonym: "activation of ubiquitin ligase activity of anaphase-promoting complex during meiotic cell cycle" EXACT []
2878 synonym: "activation of ubiquitin ligase activity of APC during meiotic cell cycle" EXACT []
2879 synonym: "anaphase promoting complex activation during meiotic cell cycle" EXACT []
2880 synonym: "APC activation during meiotic cell cycle" EXACT []
2881 synonym: "meiotic anaphase promoting complex activation" EXACT []
2882 synonym: "meiotic APC activation" EXACT []
2883 synonym: "meiotic anaphase promoting complex activator" NARROW []
2884 synonym: "meiotic anaphase-promoting complex activator" NARROW []
2885 synonym: "meiotic APC activator" NARROW []
2886 xref: GO:0051487
2887
2888 [Term]
2889 id: CCO:P0000293
2890 name: meiotic recombination checkpoint
2891 def: "A checkpoint during late prophase I (pachytene) which prevents segregation of homologous chromosomes until recombination is completed and ensures proper distribution of the genetic material to the gametes." [PMID:14718568]
2892 is_a: CCO:P0000005 ! cell cycle checkpoint
2893 is_a: CCO:P0000200 ! negative regulation of meiosis
2894 relationship: part_of CCO:P0000105 ! meiotic prophase I
2895 synonym: "pachytene checkpoint" EXACT []
2896 xref: GO:0051598
2897
2898 [Term]
2899 id: CCO:P0000294
2900 name: regulation of cell cycle
2901 def: "A cell cycle process that modulates the rate, extent or mode of the cell cycle." [GOC:ai]
2902 is_a: CCO:P0000308 ! cell cycle process
2903 synonym: "cell cycle control" EXACT []
2904 synonym: "cell cycle modulation" EXACT []
2905 synonym: "cell cycle regulation" EXACT []
2906 xref: GO:0051726
2907
2908 [Term]
2909 id: CCO:P0000295
2910 name: cell cycle switching, meiotic to mitotic cell cycle
2911 def: "The process by which a cell switches cell cycle mode from meiotic to mitotic division." [GOC:ai]
2912 is_a: CCO:P0000294 ! regulation of cell cycle
2913 synonym: "conversion to mitotic cell cycle" EXACT []
2914 synonym: "entry into mitotic cell cycle" EXACT []
2915 synonym: "initiation of mitotic cell cycle" EXACT []
2916 synonym: "cell cycle switching, meiotis to mitosis" NARROW []
2917 synonym: "conversion to mitosis" NARROW []
2918 synonym: "entry into mitosis" NARROW []
2919 synonym: "initiation of mitosis" NARROW []
2920 synonym: "mitotic entry" NARROW []
2921 xref: GO:0051727
2922
2923 [Term]
2924 id: CCO:P0000296
2925 name: cell cycle switching, mitotic to meiotic cell cycle
2926 def: "The process by which a cell switches cell cycle mode from mitotic to meiotic division." [GOC:ai]
2927 is_a: CCO:P0000294 ! regulation of cell cycle
2928 synonym: "conversion to meiotic cell cycle" EXACT []
2929 synonym: "entry into meiotic cell cycle" EXACT []
2930 synonym: "initiation of meiotic cell cycle" EXACT []
2931 synonym: "cell cycle switching, mitotis to meiosis" NARROW []
2932 synonym: "conversion to meiosis" NARROW []
2933 synonym: "entry into meiosis" NARROW []
2934 synonym: "initiation of meiosis" NARROW []
2935 synonym: "meiotic entry" NARROW []
2936 xref: GO:0051728
2937 xref: GO:0042061
2938
2939 [Term]
2940 id: CCO:P0000297
2941 name: germline cell cycle switching, mitotic to meiotic cell cycle
2942 def: "The process by which a germline cell switches cell cycle mode from mitotic to meiotic division." [GOC:ai]
2943 is_a: CCO:P0000296 ! cell cycle switching, mitotic to meiotic cell cycle
2944 synonym: "germline conversion to meiotic cell cycle" EXACT []
2945 synonym: "germline entry into meiotic cell cycle" EXACT []
2946 synonym: "germline initiation of meiotic cell cycle" EXACT []
2947 synonym: "germline cell cycle switching, mitotis to meiosis" NARROW []
2948 synonym: "germline conversion to meiosis" NARROW []
2949 synonym: "germline entry into meiosis" NARROW []
2950 synonym: "germline initiation of meiosis" NARROW []
2951 synonym: "germline meiotic entry" NARROW []
2952 xref: GO:0051729
2953
2954 [Term]
2955 id: CCO:P0000298
2956 name: meiotic sister chromatid cohesion, centromeric
2957 def: "The cell cycle process whereby centromeres of sister chromatids are joined during meiosis." [PMID:14730319, PMID:16325576]
2958 is_a: CCO:P0000308 ! cell cycle process
2959 relationship: part_of CCO:P0000240 ! meiotic sister chromatid cohesion
2960 synonym: "meiotic sister chromatid cohesion at centromere" EXACT []
2961 synonym: "sister chromatid cohesion at centromere at meiosis I" EXACT []
2962 xref: GO:0051754
2963
2964 [Term]
2965 id: CCO:P0000299
2966 name: meiotic sister chromatid arm separation
2967 def: "The cell cycle process whereby sister chromatid arms are physically detached from each other during meiosis." [GOC:ai]
2968 is_a: CCO:P0000308 ! cell cycle process
2969 relationship: part_of CCO:P0000104 ! meiosis I
2970 relationship: part_of CCO:P0000301 ! meiotic sister chromatid separation
2971 xref: GO:0051755
2972
2973 [Term]
2974 id: CCO:P0000300
2975 name: meiotic sister chromatid centromere separation
2976 def: "The cell cycle process whereby the centromeres of sister chromatids are physically detached from each other during meiosis." [GOC:ai, PMID:14730319, PMID:16325576]
2977 is_a: CCO:P0000308 ! cell cycle process
2978 relationship: part_of CCO:P0000192 ! meiotic sister chromatid segregation
2979 relationship: part_of CCO:P0000301 ! meiotic sister chromatid separation
2980 xref: GO:0051756
2981
2982 [Term]
2983 id: CCO:P0000301
2984 name: meiotic sister chromatid separation
2985 def: "The process by which sister chromatids are physically detached from each other during meiosis." [GOC:ai, PMID:14730319, PMID:16325576]
2986 is_a: CCO:P0000254 ! meiotic chromosome separation
2987 xref: GO:0051757
2988
2989 [Term]
2990 id: CCO:P0000302
2991 name: homologous chromosome movement towards spindle pole during meiosis I
2992 def: "The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I." [GOC:ai]
2993 is_a: CCO:P0000134 ! meiotic chromosome movement towards spindle pole
2994 relationship: part_of CCO:P0000191 ! homologous chromosome segregation
2995 synonym: "meiosis I, homologous chromosome movement towards spindle pole" EXACT []
2996 xref: GO:0051758
2997
2998 [Term]
2999 id: CCO:P0000303
3000 name: sister chromosome movement towards spindle pole during meiosis II
3001 def: "The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II." [GOC:ai]
3002 is_a: CCO:P0000134 ! meiotic chromosome movement towards spindle pole
3003 relationship: part_of CCO:P0000192 ! meiotic sister chromatid segregation
3004 synonym: "meiosis II, sister chromosome movement towards spindle pole" EXACT []
3005 xref: GO:0051759
3006
3007 [Term]
3008 id: CCO:P0000304
3009 name: meiotic sister chromatid cohesion, arms
3010 def: "The cell cycle process whereby the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis." [PMID:14730319, PMID:16325576]
3011 is_a: CCO:P0000308 ! cell cycle process
3012 relationship: part_of CCO:P0000240 ! meiotic sister chromatid cohesion
3013 synonym: "meiotic sister chromatid cohesion along arms" EXACT []
3014 synonym: "sister chromatid cohesion along arms at meiosis I" EXACT []
3015 xref: GO:0051760
3016
3017 [Term]
3018 id: CCO:P0000305
3019 name: lateral element assembly
3020 def: "The cell cycle process whereby lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements." [PMID:11463847]
3021 is_a: CCO:P0000308 ! cell cycle process
3022 relationship: part_of CCO:P0000107 ! synaptonemal complex assembly
3023 xref: GO:0051878
3024
3025 [Term]
3026 id: CCO:P0000306
3027 name: maintenance of contractile ring localization
3028 def: "The processes by which a contractile ring is maintained in a location and prevented from moving elsewhere." [GOC:mah]
3029 relationship: part_of CCO:P0000153 ! cytokinesis, contractile ring maintenance
3030 synonym: "cytokinetic ring anchoring" RELATED []
3031 xref: GO:0032189
3032
3033 [Term]
3034 id: CCO:P0000307
3035 name: cell cycle arrest of committed forebrain neuronal progenitor cell
3036 def: "The process by which progression through the cell cycle is halted in a cell that has been committed to become a neuron that will reside in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447]
3037 is_a: CCO:P0000057 ! cell cycle arrest
3038 comment: This term was added by GO_REF:0000021.
3039 xref: GO:0021883
3040
3041 [Term]
3042 id: CCO:P0000308
3043 name: cell cycle process
3044 def: "A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:isa_complete]
3045 relationship: part_of CCO:P0000056 ! cell cycle
3046 xref: GO:0022402
3047
3048 [Term]
3049 id: CCO:P0000309
3050 name: cell cycle phase
3051 def: "A cell cycle process composed of one of the morphological steps through which a cell progresses during successive cell replication or nuclear replication events." [GOC:isa_complete]
3052 is_a: CCO:P0000308 ! cell cycle process
3053 xref: GO:0022403
3054
3055 [Term]
3056 id: CCO:P0000310
3057 name: spindle elongation
3058 def: "The cell cycle process whereby the distance is lengthened between poles of the spindle." [GOC:ai]
3059 is_a: CCO:P0000308 ! cell cycle process
3060 xref: GO:0051231
3061
3062 [Term]
3063 id: CCO:P0000311
3064 name: spindle midzone assembly
3065 def: "The cell cycle process whereby spindle midzone is formed. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap." [GOC:ai, PMID:15296749]
3066 is_a: CCO:P0000308 ! cell cycle process
3067 synonym: "spindle midzone biogenesis" EXACT []
3068 synonym: "spindle midzone biosynthesis" EXACT []
3069 synonym: "spindle midzone formation" EXACT []
3070 xref: GO:0051255
3071
3072 [Term]
3073 id: CCO:P0000312
3074 name: chromosome separation
3075 def: "The cell cycle process whereby paired chromosomes are detached from each other. In budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions." [GOC:ai]
3076 is_a: CCO:P0000308 ! cell cycle process
3077 xref: GO:0051304
3078
3079 [Term]
3080 id: CCO:P0000313
3081 name: distributive segregation
3082 def: "The cell cycle process whereby genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a \"backup\" mechanism to ensure the segregation of homologs that have failed to cross over -- either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) -- but nevertheless segregate normally." [GOC:expert_rsh, GOC:ma, GOC:sart]
3083 is_a: CCO:P0000189 ! meiotic chromosome segregation
3084 xref: GO:0032837
3085
3086 [Term]
3087 id: CCO:P0000314
3088 name: regulation of spindle elongation
3089 def: "Any process that modulates the frequency, rate or extent of the cell cycle process whereby the distance is lengthened between poles of the spindle." [GOC:mah]
3090 relationship: part_of CCO:P0000310 ! spindle elongation
3091 xref: GO:0032887
3092
3093 [Term]
3094 id: CCO:P0000315
3095 name: regulation of mitotic spindle elongation
3096 def: "Any process that modulates the frequency, rate or extent of the cell cycle process whereby the distance is lengthened between poles of the mitotic spindle." [GOC:mah]
3097 is_a: CCO:P0000314 ! regulation of spindle elongation
3098 relationship: part_of CCO:P0000001 ! mitotic spindle elongation
3099 xref: GO:0032888
3100
3101 [Term]
3102 id: CCO:T0000001
3103 name: Tetrapoda organism
3104 is_a: CCO:T0000050 ! Sarcopterygii organism
3105 xref: NCBI:32523
3106
3107 [Term]
3108 id: CCO:T0000002
3109 name: Ascomycota organism
3110 is_a: CCO:T0000025 ! Fungi organism
3111 xref: NCBI:4890
3112
3113 [Term]
3114 id: CCO:T0000003
3115 name: Theria organism
3116 is_a: CCO:T0000055 ! Mammalia organism
3117 xref: NCBI:32525
3118
3119 [Term]
3120 id: CCO:T0000004
3121 name: Homo sapiens organism
3122 is_a: CCO:T0000052 ! Homo organism
3123 xref: NCBI:9606
3124
3125 [Term]
3126 id: CCO:T0000005
3127 name: Coelomata organism
3128 is_a: CCO:T0000035 ! Bilateria organism
3129 xref: NCBI:33316
3130
3131 [Term]
3132 id: CCO:T0000006
3133 name: Euteleostomi organism
3134 is_a: CCO:T0000026 ! Teleostomi organism
3135 xref: NCBI:117571
3136
3137 [Term]
3138 id: CCO:T0000007
3139 name: rosids organism
3140 is_a: CCO:T0000037 ! core eudicotyledons organism
3141 xref: NCBI:71275
3142
3143 [Term]
3144 id: CCO:T0000008
3145 name: Schizosaccharomyces organism
3146 is_a: CCO:T0000054 ! Schizosaccharomycetaceae organism
3147 xref: NCBI:4895
3148
3149 [Term]
3150 id: CCO:T0000009
3151 name: Streptophyta organism
3152 is_a: CCO:T0000012 ! Viridiplantae organism
3153 xref: NCBI:35493
3154
3155 [Term]
3156 id: CCO:T0000010
3157 name: Magnoliophyta organism
3158 is_a: CCO:T0000031 ! Spermatophyta organism
3159 xref: NCBI:3398
3160
3161 [Term]
3162 id: CCO:T0000011
3163 name: organism
3164 is_a: CCO:U0000001 ! cell-cycle continuant
3165 xref: NCBI:1
3166
3167 [Term]
3168 id: CCO:T0000012
3169 name: Viridiplantae organism
3170 is_a: CCO:T0000032 ! Eukaryota organism
3171 xref: NCBI:33090
3172
3173 [Term]
3174 id: CCO:T0000013
3175 name: Schizosaccharomycetales organism
3176 is_a: CCO:T0000024 ! Schizosaccharomycetes organism
3177 xref: NCBI:34346
3178
3179 [Term]
3180 id: CCO:T0000014
3181 name: Saccharomycetales organism
3182 is_a: CCO:T0000039 ! Saccharomycetes organism
3183 xref: NCBI:4892
3184
3185 [Term]
3186 id: CCO:T0000015
3187 name: eudicotyledons organism
3188 is_a: CCO:T0000010 ! Magnoliophyta organism
3189 xref: NCBI:71240
3190
3191 [Term]
3192 id: CCO:T0000016
3193 name: Saccharomyces cerevisiae organism
3194 is_a: CCO:T0000019 ! Saccharomyces organism
3195 xref: NCBI:4932
3196
3197 [Term]
3198 id: CCO:T0000017
3199 name: Schizosaccharomyces pombe organism
3200 is_a: CCO:T0000008 ! Schizosaccharomyces organism
3201 xref: NCBI:4896
3202
3203 [Term]
3204 id: CCO:T0000018
3205 name: Euphyllophyta organism
3206 is_a: CCO:T0000030 ! Tracheophyta organism
3207 xref: NCBI:78536
3208
3209 [Term]
3210 id: CCO:T0000019
3211 name: Saccharomyces organism
3212 is_a: CCO:T0000034 ! Saccharomycetaceae organism
3213 xref: NCBI:4930
3214
3215 [Term]
3216 id: CCO:T0000020
3217 name: Metazoa organism
3218 is_a: CCO:T0000041 ! Fungi/Metazoa group organism
3219 xref: NCBI:33208
3220
3221 [Term]
3222 id: CCO:T0000021
3223 name: Homo/Pan/Gorilla group organism
3224 is_a: CCO:T0000058 ! Hominidae organism
3225 xref: NCBI:207598
3226
3227 [Term]
3228 id: CCO:T0000022
3229 name: Brassicales organism
3230 is_a: CCO:T0000060 ! eurosids II organism
3231 xref: NCBI:3699
3232
3233 [Term]
3234 id: CCO:T0000023
3235 name: Embryophyta organism
3236 is_a: CCO:T0000051 ! Streptophytina organism
3237 xref: NCBI:3193
3238
3239 [Term]
3240 id: CCO:T0000024
3241 name: Schizosaccharomycetes organism
3242 is_a: CCO:T0000002 ! Ascomycota organism
3243 xref: NCBI:147554
3244
3245 [Term]
3246 id: CCO:T0000025
3247 name: Fungi organism
3248 is_a: CCO:T0000041 ! Fungi/Metazoa group organism
3249 xref: NCBI:4751
3250
3251 [Term]
3252 id: CCO:T0000026
3253 name: Teleostomi organism
3254 is_a: CCO:T0000049 ! Gnathostomata organism
3255 xref: NCBI:117570
3256
3257 [Term]
3258 id: CCO:T0000027
3259 name: Brassicaceae organism
3260 is_a: CCO:T0000022 ! Brassicales organism
3261 xref: NCBI:3700
3262
3263 [Term]
3264 id: CCO:T0000028
3265 name: Primates organism
3266 is_a: CCO:T0000053 ! Euarchontoglires organism
3267 xref: NCBI:9443
3268
3269 [Term]
3270 id: CCO:T0000029
3271 name: Hominoidea organism
3272 is_a: CCO:T0000046 ! Catarrhini organism
3273 xref: NCBI:314295
3274
3275 [Term]
3276 id: CCO:T0000030
3277 name: Tracheophyta organism
3278 is_a: CCO:T0000023 ! Embryophyta organism
3279 xref: NCBI:58023
3280
3281 [Term]
3282 id: CCO:T0000031
3283 name: Spermatophyta organism
3284 is_a: CCO:T0000018 ! Euphyllophyta organism
3285 xref: NCBI:58024
3286
3287 [Term]
3288 id: CCO:T0000032
3289 name: Eukaryota organism
3290 is_a: CCO:T0000040 ! cellular organisms organism
3291 xref: NCBI:2759
3292
3293 [Term]
3294 id: CCO:T0000033
3295 name: Arabidopsis thaliana organism
3296 is_a: CCO:T0000057 ! Arabidopsis organism
3297 xref: NCBI:3702
3298
3299 [Term]
3300 id: CCO:T0000034
3301 name: Saccharomycetaceae organism
3302 is_a: CCO:T0000014 ! Saccharomycetales organism
3303 xref: NCBI:4893
3304
3305 [Term]
3306 id: CCO:T0000035
3307 name: Bilateria organism
3308 is_a: CCO:T0000048 ! Eumetazoa organism
3309 xref: NCBI:33213
3310
3311 [Term]
3312 id: CCO:T0000036
3313 name: Vertebrata organism
3314 is_a: CCO:T0000044 ! Craniata organism
3315 xref: NCBI:7742
3316
3317 [Term]
3318 id: CCO:T0000037
3319 name: core eudicotyledons organism
3320 is_a: CCO:T0000015 ! eudicotyledons organism
3321 xref: NCBI:91827
3322
3323 [Term]
3324 id: CCO:T0000038
3325 name: Saccharomycotina organism
3326 is_a: CCO:T0000002 ! Ascomycota organism
3327 xref: NCBI:147537
3328
3329 [Term]
3330 id: CCO:T0000039
3331 name: Saccharomycetes organism
3332 is_a: CCO:T0000038 ! Saccharomycotina organism
3333 xref: NCBI:4891
3334
3335 [Term]
3336 id: CCO:T0000040
3337 name: cellular organisms organism
3338 is_a: CCO:T0000011 ! organism
3339 xref: NCBI:131567
3340
3341 [Term]
3342 id: CCO:T0000041
3343 name: Fungi/Metazoa group organism
3344 is_a: CCO:T0000032 ! Eukaryota organism
3345 xref: NCBI:33154
3346
3347 [Term]
3348 id: CCO:T0000042
3349 name: Amniota organism
3350 is_a: CCO:T0000001 ! Tetrapoda organism
3351 xref: NCBI:32524
3352
3353 [Term]
3354 id: CCO:T0000043
3355 name: Deuterostomia organism
3356 is_a: CCO:T0000005 ! Coelomata organism
3357 xref: NCBI:33511
3358
3359 [Term]
3360 id: CCO:T0000044
3361 name: Craniata organism
3362 is_a: CCO:T0000045 ! Chordata organism
3363 xref: NCBI:89593
3364
3365 [Term]
3366 id: CCO:T0000045
3367 name: Chordata organism
3368 is_a: CCO:T0000043 ! Deuterostomia organism
3369 xref: NCBI:7711
3370
3371 [Term]
3372 id: CCO:T0000046
3373 name: Catarrhini organism
3374 is_a: CCO:T0000047 ! Simiiformes organism
3375 xref: NCBI:9526
3376
3377 [Term]
3378 id: CCO:T0000047
3379 name: Simiiformes organism
3380 is_a: CCO:T0000059 ! Haplorrhini organism
3381 xref: NCBI:314293
3382
3383 [Term]
3384 id: CCO:T0000048
3385 name: Eumetazoa organism
3386 is_a: CCO:T0000020 ! Metazoa organism
3387 xref: NCBI:6072
3388
3389 [Term]
3390 id: CCO:T0000049
3391 name: Gnathostomata organism
3392 is_a: CCO:T0000036 ! Vertebrata organism
3393 xref: NCBI:7776
3394
3395 [Term]
3396 id: CCO:T0000050
3397 name: Sarcopterygii organism
3398 is_a: CCO:T0000006 ! Euteleostomi organism
3399 xref: NCBI:8287
3400
3401 [Term]
3402 id: CCO:T0000051
3403 name: Streptophytina organism
3404 is_a: CCO:T0000009 ! Streptophyta organism
3405 xref: NCBI:131221
3406
3407 [Term]
3408 id: CCO:T0000052
3409 name: Homo organism
3410 is_a: CCO:T0000021 ! Homo/Pan/Gorilla group organism
3411 xref: NCBI:9605
3412
3413 [Term]
3414 id: CCO:T0000053
3415 name: Euarchontoglires organism
3416 is_a: CCO:T0000056 ! Eutheria organism
3417 xref: NCBI:314146
3418
3419 [Term]
3420 id: CCO:T0000054
3421 name: Schizosaccharomycetaceae organism
3422 is_a: CCO:T0000013 ! Schizosaccharomycetales organism
3423 xref: NCBI:4894
3424
3425 [Term]
3426 id: CCO:T0000055
3427 name: Mammalia organism
3428 is_a: CCO:T0000042 ! Amniota organism
3429 xref: NCBI:40674
3430
3431 [Term]
3432 id: CCO:T0000056
3433 name: Eutheria organism
3434 is_a: CCO:T0000003 ! Theria organism
3435 xref: NCBI:9347
3436
3437 [Term]
3438 id: CCO:T0000057
3439 name: Arabidopsis organism
3440 is_a: CCO:T0000027 ! Brassicaceae organism
3441 xref: NCBI:3701
3442
3443 [Term]
3444 id: CCO:T0000058
3445 name: Hominidae organism
3446 is_a: CCO:T0000029 ! Hominoidea organism
3447 xref: NCBI:9604
3448
3449 [Term]
3450 id: CCO:T0000059
3451 name: Haplorrhini organism
3452 is_a: CCO:T0000028 ! Primates organism
3453 xref: NCBI:376913
3454
3455 [Term]
3456 id: CCO:T0000060
3457 name: eurosids II organism
3458 is_a: CCO:T0000007 ! rosids organism
3459 xref: NCBI:91836
3460
3461 [Term]
3462 id: CCO:U0000000
3463 name: cell-cycle entity
3464 def: "A process or continuant." [CCO:ea]
3465 synonym: "cell cycle entity" EXACT [CCO:ea]
3466
3467 [Term]
3468 id: CCO:U0000001
3469 name: cell-cycle continuant
3470 def: "Entities which endure, or continue to exist, through time while undergoing different sort of changes, including changes of place." [PMID:15892874]
3471 disjoint_from: CCO:U0000002
3472 is_a: CCO:U0000000 ! cell-cycle entity
3473 synonym: "cell cycle continuant" EXACT [CCO:ea]
3474 synonym: "endurant" EXACT [PMID:15892874]
3475 synonym: "thing" BROAD [PMID:15892874]
3476
3477 [Term]
3478 id: CCO:U0000002
3479 name: cell-cycle process
3480 def: "Entities that unfold themselves in successive temporal phases." [PMID:15892874]
3481 disjoint_from: CCO:U0000001
3482 is_a: CCO:U0000000 ! cell-cycle entity
3483 synonym: "perdurant" EXACT [PMID:15892874]
3484 synonym: "ocurrent" BROAD [PMID:15892874]
3485 synonym: "cell cycle process" EXACT [CCO:ea]
3486
3487 [Term]
3488 id: CCO:U0000003
3489 name: biopolymer
3490 def: "A polymer, such as a protein, nucleic acid, or transcript, ocurring in, or formed by, living systems." [CCO:ea]
3491 is_a: CCO:U0000001 ! cell-cycle continuant
3492 synonym: "bio-polymer" EXACT [CCO:ea]
3493
3494 [Term]
3495 id: CCO:U0000004
3496 name: gene
3497 def: "A locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions and/or other functional sequence regions." [SO:0000704]
3498 disjoint_from: CCO:U0000005
3499 is_a: CCO:U0000003 ! biopolymer
3500 xref: SO:0000704
3501
3502 [Term]
3503 id: CCO:U0000005
3504 name: protein
3505 def: "One or more polypeptides which may, or may not, be covalently bonded, and which assume a native secondary and tertiary structure." [SO:0000358]
3506 disjoint_from: CCO:U0000004
3507 is_a: CCO:U0000003 ! biopolymer
3508 xref: SO:0000358
3509
3510 [Term]
3511 id: CCO:U0000006
3512 name: transcript
3513 def: "An RNA synthesized on a DNA or RNA template by an RNA polymerase." [SO:0000673]
3514 is_a: CCO:U0000003 ! biopolymer
3515 xref: SO:0000673
3516
3517 [Term]
3518 id: CCO:U0000007
3519 name: cell cycle protein
3520 def: "Cell cycle proteins are polymeric macromolecules composed of one or more long chains of amino acids linked by peptide bonds, usually coiled and folded into complex globular or fibrous structures." [CCO:ea]
3521 is_a: CCO:U0000005 ! protein
3522 is_a: CCO:U0000001 ! cell cycle continuant
3523
3524 [Term]
3525 id: CCO:U0000008
3526 name: cell cycle gene
3527 def: "Cell cycle units of heredity which (except for polygenes) may be regarded as the controlling agents in the expression of single phenotypic characters and are usually segments of a chromosome at fixed positions relative to each other." [CCO:ea]
3528 is_a: CCO:U0000004 ! gene
3529 is_a: CCO:U0000001 ! cell cycle continuant
3530
3531 [Term]
3532 id: CCO:U0000009
3533 name: interaction
3534 is_a: CCO:U0000002 ! cell-cycle process
3535
3536 [Term]
3537 id: CCO:U0000010
3538 name: complex
3539 def: "Any distinct chemical species in which two or more identical or nonidentical chemical species are associated." [CCO:ea]
3540 is_a: CCO:U0000001 ! cell-cycle continuant
3541
3542 [Term]
3543 id: CCO:U0000011
3544 name: modified protein
3545 def: "A modified protein" [CCO:ea]
3546 is_a: CCO:U0000005 ! protein
3547
3548 [Term]
3549 id: CCO:Y0000025
3550 name: physical association
3551 is_a: CCO:U0000009 ! interaction
3552
3553 [Term]
3554 id: CCO:U0000030
3555 name: modified protein
3556 def: "A protein which underwent any sort of modification (e.g. phosphorylation)" [CCO:ea]
3557 is_a: CCO:U0000005 ! protein
3558
3559 [Term]
3560 id: CCO:U0000012
3561 name: cell cycle modified protein
3562 def: "A cell cycle protein which underwent any sort of modification (e.g. phosphorylation)" [CCO:ea]
3563 is_a: CCO:U0000011 ! modified protein
3564 is_a: CCO:U0000007 ! cell cycle protein
3565
3566 [Typedef]
3567 id: adjacent_to
3568 name: adjacent_to
3569 def: "C adjacent to C' if and only if: given any instance c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c and c' are in spatial proximity" [PMID:15892874]
3570 comment: Note that adjacent_to as thus defined is not a symmetric relation, in contrast to its instance-level counterpart. For it can be the case that Cs are in general such as to be adjacent to instances of C1 while no analogous statement holds for C1s in general in relation to instances of C. Examples are: nuclear membrane adjacent_to cytoplasm; seminal vesicle adjacent_to urinary bladder; ovary adjacent_to parietal pelvic peritoneum
3571 is_a: relationship ! relationship
3572 xref: OBO_REL:adjacent_to
3573
3574 [Typedef]
3575 id: agent_in
3576 name: agent_in
3577 is_a: relationship ! relationship
3578 xref: OBO_REL:agent_in
3579
3580 [Typedef]
3581 id: association
3582 name: association
3583 def: "C in association with C' produces C'' if and only if for all c belonging to C and c' belongin to C', exists a c'' (belonging to C'') which is the result of the reversible union between c and c'." [CCO:ea]
3584 comment: Ternary relationship. See http://www.w3.org/TR/swbp-n-aryRelations/ for the OWL equivalent. The dissociation is a reversible splitting into simpler entities.
3585 is_a: relationship ! relationship
3586 xref: CCO_REL:association
3587
3588 [Typedef]
3589 id: catalyses
3590 name: catalyses
3591 def: "C catalyses P if and only if for all c (catalyst) belonging to C, exists a p (belonging to P) which chemical reaction rate is increased by c." [CCO:ea]
3592 comment: C inhibits P if and only if for all c (inhibitor) belonging to C, exists a p (belonging to P) which chemical reaction rate is reduced or prevented by c.
3593 synonym: "activates" EXACT []
3594 is_a: relationship ! relationship
3595 xref: CCO_REL:catalyses
3596
3597 [Typedef]
3598 id: contained_in
3599 name: contained_in
3600 def: "C contained_in C' if and only if: given any instance c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c located_in c' at t, and it is not the case that c *overlaps* c' at t. (c' is a conduit or cavity.)" [PMID:15892874]
3601 comment: Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):
3602 is_a: relationship ! relationship
3603 xref: OBO_REL:contained_in
3604
3605 [Typedef]
3606 id: contains
3607 name: contains
3608 is_a: relationship ! relationship
3609 xref: OBO_REL:contains
3610
3611 [Typedef]
3612 id: degradates
3613 name: degradates
3614 def: "C is degradated (into NIL) if and only if for all c belonging to C, exists c', c'', ... (belonging to C', C'', ...) which are the result of any undesired breakdown of c with impairment or loss of its characteristic properties." [CCO:ea]
3615 comment: NIL entity must be created.
3616 synonym: "decomposition" EXACT []
3617 synonym: "catabolism" EXACT []
3618 is_a: relationship ! relationship
3619 xref: CCO_REL:degradates
3620
3621 [Typedef]
3622 id: derived_into
3623 name: derived_into
3624 is_a: relationship ! relationship
3625 is_transitive: true
3626 xref: OBO_REL:derived_into
3627
3628 [Typedef]
3629 id: derives_from
3630 name: derives_from
3631 def: "Derivation on the instance level (*derives_from*) holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. We say that one class C derives_from class C' if instances of C are connected to instances of C' via some chain of instance-level derivation relations. Example: osteocyte derives_from osteoblast. Formally: C derives_immediately_from C' if and only if: given any c and any t, if c instantiates C at time t, then there is some c' and some t', such that c' instantiates C' at t' and t' earlier-than t and c *derives_from* c'. C derives_from C' if and only if: there is an chain of immediate derivation relations connecting C to C'." [PMID:15892874]
3632 comment: Derivation as a relation between instances. The temporal relation of derivation is more complex. Transformation, on the instance level, is just the relation of identity: each adult is identical to some child existing at some earlier time. Derivation on the instance-level is a relation holding between non-identicals. More precisely, it holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Thus we will have axioms to the effect that from c derives_from c1 we can infer that c and c1 are not identical and that there is some instant of time t such that c1 exists only prior to and c only subsequent to t. We will also be able to infer that the spatial region occupied by c as it begins to exist at t overlaps with the spatial region occupied by c1 as it ceases to exist in the same instant.
3633 is_a: relationship ! relationship
3634 is_transitive: true
3635 xref: OBO_REL:derives_from
3636
3637 [Typedef]
3638 id: encoded_by
3639 name: encoded_by
3640 def: "p is encoded by g where p is a Protein and g a Gene." [CCO:ea]
3641 synonym: "is_produced_by" EXACT [CCO:ea]
3642 synonym: "coded_by" EXACT [CCO:ea]
3643 is_a: relationship ! relationship
3644 xref: CCO_REL:encoded_by
3645
3646 [Typedef]
3647 id: codes_for
3648 name: codes_for
3649 def: "g encodes for p where g a Gene and p is a Protein." [CCO:ea]
3650 synonym: "produces" EXACT [CCO:ea]
3651 synonym: "encodes_for" EXACT [CCO:ea]
3652 is_a: relationship ! relationship
3653 xref: CCO_REL:codes_for
3654
3655 [Typedef]
3656 id: has_agent
3657 name: has_agent
3658 def: "As for has_participant, but with the additional condition that the component instance is causally active in the relevant process" [PMID:15892874]
3659 is_a: relationship ! relationship
3660 xref: OBO_REL:has_agent
3661
3662 [Typedef]
3663 id: has_improper_part
3664 name: has_improper_part
3665 is_a: part_of ! part_of
3666 is_reflexive: true
3667 is_transitive: true
3668 xref: OBO_REL:has_improper_part
3669
3670 [Typedef]
3671 id: has_integral_part
3672 name: has_integral_part
3673 is_a: part_of ! part_of
3674 is_reflexive: true
3675 is_anti_symmetric: true
3676 is_transitive: true
3677 xref: OBO_REL:has_integral_part
3678
3679 [Typedef]
3680 id: has_part
3681 name: has_part
3682 is_a: relationship ! relationship
3683 is_reflexive: true
3684 is_anti_symmetric: true
3685 is_transitive: true
3686 xref: OBO_REL:has_part
3687
3688 [Typedef]
3689 id: has_participant
3690 name: has_participant
3691 def: "P has_participant C if and only if: given any process p that instantiates P there is some continuant c, and some time t, such that: c instantiates C at t and c participates in p at t" [PMID:15892874]
3692 comment: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
3693 is_a: relationship ! relationship
3694 xref: OBO_REL:has_participant
3695
3696 [Typedef]
3697 id: has_proper_part
3698 name: has_proper_part
3699 is_a: part_of ! part_of
3700 is_transitive: true
3701 xref: OBO_REL:has_proper_part
3702
3703 [Typedef]
3704 id: improper_part_of
3705 name: improper_part_of
3706 def: "As for part_of, with the additional constraint that subject and object may be identical" [PMID:15892874]
3707 is_a: part_of ! part_of
3708 is_reflexive: true
3709 is_transitive: true
3710 xref: OBO_REL:improper_part_of
3711
3712 [Typedef]
3713 id: integral_part_of
3714 name: integral_part_of
3715 def: "C integral_part_of C' if and only if: C part_of C' AND C' has_part C" [PMID:15892874]
3716 is_a: part_of ! part_of
3717 is_reflexive: true
3718 is_anti_symmetric: true
3719 is_transitive: true
3720 xref: OBO_REL:integral_part_of
3721
3722 [Typedef]
3723 id: interacts_with
3724 name: interacts_with
3725 def: "C interacts_with C' if and only if for all c belonging to C, exists a c' (belonging to C') which plays a role with c'." [CCO:ea]
3726 is_a: relationship ! relationship
3727 is_symmetric: true
3728 is_transitive: true
3729 xref: CCO_REL:interacts_with
3730
3731 [Typedef]
3732 id: is_a
3733 name: is_a
3734 builtin: true
3735 def: "For continuants: C is_a C' if and only if: given any c that instantiates C at a time t, c instantiates C' at t. For processes: P is_a P' if and only if: that given any p that instantiates P, then p instantiates P'." [PMID:15892874]
3736 comment: The is_a relationship is considered axiomatic by the obo file format specification, and by OWL
3737 synonym: "is_subtype_of" EXACT []
3738 is_reflexive: true
3739 is_anti_symmetric: true
3740 is_transitive: true
3741 xref: OBO_REL:is_a
3742 xref: owl:subClassOf
3743
3744 [Typedef]
3745 id: located_in
3746 name: located_in
3747 def: "C located_in C' if and only if: given any c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c *located_in* c'. (Here *located_in* is the instance-level location relation.)" [PMID:15892874]
3748 comment: Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus
3749 is_a: relationship ! relationship
3750 is_reflexive: true
3751 is_transitive: true
3752 xref: OBO_REL:located_in
3753
3754 [Typedef]
3755 id: location_of
3756 name: location_of
3757 is_a: relationship ! relationship
3758 is_reflexive: true
3759 is_transitive: true
3760 xref: OBO_REL:location_of
3761
3762 [Typedef]
3763 id: part_of
3764 name: part_of
3765 def: "For continuants: C part_of C' if and only if: given any c that instantiates C at a time t, there is some c' such that c' instantiates C' at time t, and c *part_of* c' at t. For processes: P part_of P' if and only if: given any p that instantiates P at a time t, there is some p' such that p' instantiates P' at time t, and p *part_of* p' at t. (Here *part_of* is the instance-level part-relation.)" [PMID:15892874]
3766 comment: Parthood as a relation between instances: The primitive instance-level relation p part_of p1 is illustrated in assertions such as: this instance of rhodopsin mediated phototransduction part_of this instance of visual perception. This relation satisfies at least the following standard axioms of mereology: reflexivity (for all p, p part_of p); anti-symmetry (for all p, p1, if p part_of p1 and p1 part_of p then p and p1 are identical); and transitivity (for all p, p1, p2, if p part_of p1 and p1 part_of p2, then p part_of p2). Analogous axioms hold also for parthood as a relation between spatial regions. For parthood as a relation between continuants, these axioms need to be modified to take account of the incorporation of a temporal argument. Thus for example the axiom of transitivity for continuants will assert that if c part_of c1 at t and c1 part_of c2 at t, then also c part_of c2 at t. Parthood as a relation between classes: To define part_of as a relation between classes we again need to distinguish the two cases of continuants and processes, even though the explicit reference to instants of time now falls away. For continuants, we have C part_of C1 if and only if any instance of C at any time is an instance-level part of some instance of C1 at that time, as for example in: cell nucleus part_ of cell.
3767 is_a: relationship ! relationship
3768 is_reflexive: true
3769 is_anti_symmetric: true
3770 is_transitive: true
3771 xref: OBO_REL:part_of
3772
3773 [Typedef]
3774 id: participates_in
3775 name: participates_in
3776 def: "C participates_in P if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea]
3777 is_a: relationship ! relationship
3778 xref: OBO_REL:participates_in
3779 xref: CCO_REL:participates_in
3780
3781 [Typedef]
3782 id: preceded_by
3783 name: preceded_by
3784 def: "P preceded_by P' if and only if: given any process p that instantiates P at a time t, there is some process p' such that p' instantiates P' at time t', and t' is earlier than t. " [PMID:15892874]
3785 comment: An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
3786 is_a: relationship ! relationship
3787 is_transitive: true
3788 xref: OBO_REL:preceded_by
3789
3790 [Typedef]
3791 id: precedes
3792 name: precedes
3793 is_a: relationship ! relationship
3794 is_transitive: true
3795 xref: OBO_REL:precedes
3796
3797 [Typedef]
3798 id: proper_part_of
3799 name: proper_part_of
3800 def: "As for part_of, with the additional constraint that subject and object are distinct" [PMID:15892874]
3801 is_a: part_of ! part_of
3802 is_transitive: true
3803 xref: OBO_REL:proper_part_of
3804
3805 [Typedef]
3806 id: relationship
3807 name: relationship
3808 def: "A relationship between two classes (terms). Relationships between classes are expressed in terms of relations on underlying instances." []
3809 xref: OBO_REL:relationship
3810
3811 [Typedef]
3812 id: transformation_of
3813 name: transformation_of
3814 def: "Relation between two classes, in which instances retain their identity yet change their classification by virtue of some kind of transformation. Formally: C transformation_of C' if and only if given any c and any t, if c instantiates C at time t, then for some t', c instantiates C' at t' and t' earlier t, and there is no t2 such that c instantiates C at t2 and c instantiates C' at t2." [PMID:15892874]
3815 comment: When an embryonic oenocyte (a type of insect cell) is transformed into a larval oenocyte, one and the same continuant entity preserves its identity while instantiating distinct classes at distinct times. The class-level relation transformation_of obtains between continuant classes C and C1 wherever each instance of the class C is such as to have existed at some earlier time as an instance of the distinct class C1 (see Figure 2 in paper). This relation is illustrated first of all at the molecular level of granularity by the relation between mature RNA and the pre-RNA from which it is processed, or between (UV-induced) thymine-dimer and thymine dinucleotide. At coarser levels of granularity it is illustrated by the transformations involved in the creation of red blood cells, for example, from reticulocyte to erythrocyte, and by processes of development, for example, from larva to pupa, or from (post-gastrular) embryo to fetus or from child to adult. It is also manifest in pathological transformations, for example, of normal colon into carcinomatous colon. In each such case, one and the same continuant entity instantiates distinct classes at different times in virtue of phenotypic changes.
3816 is_a: relationship ! relationship
3817 is_transitive: true
3818 xref: OBO_REL:transformation_of
3819
3820 [Typedef]
3821 id: transforms_into
3822 name: transforms_into
3823 is_a: relationship ! relationship
3824 is_transitive: true
3825 xref: CCO_REL:transforms_into
3826
3827 [Typedef]
3828 id: has_source
3829 name: has_source
3830 def: "o originates from O where o is a gene or gene product and O an organism." [CCO:ea]
3831 is_a: relationship ! relationship
3832 xref: CCO_REL:has_source
3833
3834 [Typedef]
3835 id: source_of
3836 name: source_of
3837 def: "O source of o where O is an organism and o a gene or gene product." [CCO:ea]
3838 is_a: relationship ! relationship
3839 xref: CCO_REL:source_of
3840
3841 [Typedef]
3842 id: has_function
3843 name: has_function
3844 is_a: relationship ! relationship
3845 xref: OBO_REL:has_function