# HG changeset patch # User iuc # Date 1432062186 14400 # Node ID cbf9c67cd7313bc2b4a1d9708ec54e7a7cb5538b planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/packages/package_snpeff_4_1 commit 0c094c3df9574cb057ccb65878f98f300d5b0a09 diff -r 000000000000 -r cbf9c67cd731 tool_dependencies.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_dependencies.xml Tue May 19 15:03:06 2015 -0400 @@ -0,0 +1,47 @@ + + + + + + https://downloads.sourceforge.net/project/snpeff/snpEff_v4_1_core.zip + + . + $INSTALL_DIR + + sed -i.orig -e 's;http://downloads.sourceforge.net/project/snpeff/databases;https://snpeff-data.galaxyproject.org/databases;g' $INSTALL_DIR/snpEff.config + + $INSTALL_DIR + + + $INSTALL_DIR/scripts + + + + +SnpEff and SnpSift + +SnpEff ( http://snpeff.sourceforge.net/ ) is a variant annotation and effect prediction tool by Pablo Cingolani. +It annotates and predicts the effects of variants on genes (such as amino acid changes). + +This repository contains a tool_dependencies.xml file that downloads and installs SnpEff and SnpSift (SnpEff.jar and SnpSift.jar) + +The install creates an environment variable: SNPEFF_JAR_PATH that contains the path to the jar files. Tools using this can generate a command line: +java -Xmx6G -jar \$SNPEFF_JAR_PATH/snpEff.jar eff -c \$SNPEFF_JAR_PATH/snpEff.config ... + +The snpEff.config file is also installed, which specifies the default location for installed SnpEff genome databases: +data_dir = ~/snpEff/data/ + +The location of a genome database can be set via the commandline option -dataDir. Tools using this can generate a command line: +java -Xmx6G -jar \$SNPEFF_JAR_PATH/snpEff.jar eff -c \$SNPEFF_JAR_PATH/snpEff.config -dataDir path_to_data_directory snpeff_database_name input.vcf + +Another way to change the location of data_dir would be to create a symbolic link in the galaxy HOME directory: +ln -s genome_data_path/snpEff ~/snpEff + +SnpEff citation: +"A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3.", Cingolani P, Platts A, Wang le L, Coon M, Nguyen T, Wang L, Land SJ, Lu X, Ruden DM. Fly 6(2):80-92, 2012 + +SnpSift citation: +"Using Drosophila melanogaster as a model for genotoxic chemical mutational studies with a new program, SnpSift", Cingolani, P., et. al., Frontiers in Genetics, 3:35, 2012. + + +