changeset 1:5f2eacae0bb8 draft

"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/schicexplorer commit 72e1e90ac05a32dbd6fc675073429c0086048b18"
author iuc
date Tue, 10 Mar 2020 15:15:17 -0400
parents 061a8c076eb1
children 4a841ab67e3b
files macros.xml scHicQualityControl.xml test-data/scHicConsensusMatrices/consensus_matrix.mcool test-data/scHicConsensusMatrices/consensus_matrix.scool test-data/scHicCreateBulkMatrix/bulk_matrix.cool test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_TATCCTCT_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_AAGGAGTA_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_ACTGCATA_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_CTAAGCCT_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_CTCTCTAT_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_GTAAGGAG_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_TATCCTCT_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz.cool test-data/scHicMergeToMCool/Diploid_2_AGGCAGAA_AAGGAGTA_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_TATCCTCT_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_AAGGAGTA_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_ACTGCATA_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_CTAAGCCT_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_CTCTCTAT_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_GTAAGGAG_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_TATCCTCT_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz.cool test-data/scHicMergeToSCool/Diploid_2_AGGCAGAA_AAGGAGTA_R1fastqgz.cool test-data/scHicQualityControl/coverage.png test-data/scHicQualityControl/density.png test-data/scHicQualityControl/qc_report.txt test-data/test_matrix.mcool test-data/test_matrix.scool
diffstat 50 files changed, 88 insertions(+), 17 deletions(-) [+]
line wrap: on
line diff
--- a/macros.xml	Thu Jan 23 16:10:53 2020 -0500
+++ b/macros.xml	Tue Mar 10 15:15:17 2020 -0400
@@ -1,6 +1,6 @@
 <macros>
     <token name="@THREADS@">\${GALAXY_SLOTS:-4}</token>
-    <token name="@WRAPPER_VERSION@">1</token>
+    <token name="@WRAPPER_VERSION@">4</token>
 
      <xml name="requirements">
         <requirements>
@@ -9,8 +9,8 @@
         </requirements>
         <version_command>@BINARY@ --version</version_command>
     </xml>
-    <xml name='matrix_mcooler_macro'>
-        <param name='matrix_mcooler' type="data" format="mcool"
+    <xml name='matrix_scooler_macro'>
+        <param name='matrix_scooler' type="data" format="scool"
             label="Matrix to compute on"/>
     </xml>
     <xml name='matrix_cooler_multiple_macro'>
@@ -18,7 +18,7 @@
             label="Matricies to compute on" multiple="true"/>
     </xml>
     <token name="@ESCAPE_IDENTIFIER_FASTQ@"><![CDATA[re.sub('[^\s\w\.]', '_', str($fastq.element_identifier))]]></token>
-    <token name="@ESCAPE_IDENTIFIER_MCOOL@"><![CDATA[re.sub('[^\s\w\.]', '_', str($matrix_mcooler.element_identifier))]]></token>
+    <token name="@ESCAPE_IDENTIFIER_SCOOL@"><![CDATA[re.sub('[^\s\w\.]', '_', str($matrix_scooler.element_identifier))]]></token>
     <token name="@ESCAPE_IDENTIFIER_M@"><![CDATA[re.sub('[^\s\w\-\.]', '_', str($m.element_identifier))]]></token>
 
     <xml name="citations">
--- a/scHicQualityControl.xml	Thu Jan 23 16:10:53 2020 -0500
+++ b/scHicQualityControl.xml	Tue Mar 10 15:15:17 2020 -0400
@@ -8,7 +8,7 @@
     <command detect_errors="exit_code"><![CDATA[
         @BINARY@
 
-        --matrix '$matrix_mcooler'
+        --matrix '$matrix_scooler'
         #if $chromosomes:
             #set $chromosome = ' '.join([ '\'%s\'' % $chrom for $chrom in str($chromosomes).split(' ') ])
             --chromosomes $chromosome
@@ -22,7 +22,7 @@
         --outFileNameDensity plot_density.$image_file_format
         --outFileNameReadCoverage plot_read_coverage.$image_file_format
         --outFileNameQCReport report.txt
-        --outputMcool filtered_matrices.mcool
+        --outputScool filtered_matrices.scool
 
         --threads @THREADS@
 
@@ -32,7 +32,7 @@
 
     ]]></command>
     <inputs>
-        <expand macro="matrix_mcooler_macro"/>
+        <expand macro="matrix_scooler_macro"/>
         <param name="minimumReadCoverage" type="integer" value="1000000"  label="Minimum read coverage" help='Remove all samples with a lower read coverage as this value.' />   
         <param name="minimumDensity" type="float" value="0.001"  label="Minimum density" help='Remove all samples with a lower density as this value.' />   
         <param name="maximumRegionToConsider" type="integer" value="30000000"  label="Maximum region to consider" help='To compute the density, consider only this genomic distance around the diagonal.' />   
@@ -58,12 +58,12 @@
             </change_format>
         </data>
         <data name="report" from_work_dir="report.txt" format="txt" label="${tool.name} on ${on_string}: QC report"/>
-        <data name="outFileName" from_work_dir="filtered_matrices.mcool" format="mcool" label="${tool.name} on ${on_string}: Filtered matrices"/>
+        <data name="outFileName" from_work_dir="filtered_matrices.scool" format="scool" label="${tool.name} on ${on_string}: Filtered matrices"/>
         
     </outputs>
     <tests>
         <test>
-            <param name='matrix_mcooler' value='test_matrix.mcool' />
+            <param name='matrix_scooler' value='test_matrix.scool' />
             <param name='minimumReadCoverage' value='100000' />
             <param name='minimumDensity' value='0.001' />
             <param name='maximumRegionToConsider' value='30000000' />
@@ -72,11 +72,81 @@
             <output name="output_plot_density" file="scHicQualityControl/density.png" ftype="png" compare="sim_size" delta="35000"/>        
             <output name="output_plot_read_coverage" file="scHicQualityControl/coverage.png" ftype="png" compare="sim_size" delta="35000"/>        
             <output name="report" file="scHicQualityControl/qc_report.txt" ftype="txt" compare="sim_size" delta="35000"/>        
-            <output name="outFileName" ftype="mcool">
+            <output name="outFileName" ftype="scool">
                 <assert_contents>
-                    <has_h5_keys keys='Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/bins, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/bins/end, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/bins/start, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/chroms, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/chroms/name, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/indexes, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/indexes/bin1_offset, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/pixels, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/pixels/bin2_id, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/bins, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/bins/end, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/bins/start, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/chroms, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/chroms/name, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/indexes, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/indexes/bin1_offset, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/pixels, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/pixels/bin2_id, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/bins, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/bins/end, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/bins/start, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/chroms, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/chroms/name, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/indexes, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/indexes/bin1_offset, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/pixels, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/pixels/bin2_id, Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/bins, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/bins/end, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/bins/start, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/chroms, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/chroms/name, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/indexes, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/indexes/bin1_offset, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/pixels, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/pixels/bin2_id, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/bins, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/bins/end, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/bins/start, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/chroms, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/chroms/name, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/indexes, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/indexes/bin1_offset, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/pixels, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/pixels/bin2_id, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/bins, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/bins/end, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/bins/start, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/chroms, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/chroms/name, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/indexes, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/indexes/bin1_offset, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/pixels, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/pixels/bin2_id, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/bins, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/bins/end, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/bins/start, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/chroms, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/chroms/name, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/indexes, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/indexes/bin1_offset, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/indexes/chrom_offset, 
-                    Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/pixels, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/pixels/bin2_id, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/pixels/count, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/bins, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/bins/chrom, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/bins/end, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/bins/start, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/chroms, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/chroms/length, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/chroms/name, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/indexes, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/indexes/bin1_offset, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/indexes/chrom_offset, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/pixels, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/pixels/bin1_id, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/pixels/bin2_id, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/pixels/count, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/bins, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/bins/chrom, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/bins/end, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/bins/start, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/chroms, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/chroms/length, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/chroms/name, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/indexes, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/indexes/bin1_offset, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/indexes/chrom_offset, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/pixels, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/pixels/bin1_id, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/pixels/bin2_id, Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz/pixels/count, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/bins, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/bins/chrom, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/bins/end, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/bins/start, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/chroms, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/chroms/length, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/chroms/name, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/indexes, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/indexes/bin1_offset, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/indexes/chrom_offset, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/pixels, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/pixels/bin1_id, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/pixels/bin2_id, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/pixels/count, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/bins, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/bins/chrom, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/bins/end, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/bins/start, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/chroms, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/chroms/length, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/chroms/name, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/indexes, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/indexes/bin1_offset, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/indexes/chrom_offset, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/pixels, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/pixels/bin1_id, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/pixels/bin2_id, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/pixels/count, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/bins, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/bins/chrom, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/bins/end, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/bins/start, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/chroms, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/chroms/length, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/chroms/name, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/indexes, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/indexes/bin1_offset, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/indexes/chrom_offset, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/pixels, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/pixels/bin1_id, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/pixels/bin2_id, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/pixels/count'/>
-                </assert_contents>
+                    <has_h5_keys keys='Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/bins,
+                                    Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/bins/end, 
+                                    Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/bins/start, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/chroms, 
+                                    Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/chroms/name,
+                                    Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/indexes, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/indexes/bin1_offset, 
+                                    Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/pixels, 
+                                    Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/pixels/bin2_id,
+                                    Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/bins, 
+                                    Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/bins/end,
+                                    Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/bins/start, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/chroms, 
+                                    Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/chroms/name,
+                                    Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/indexes, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/indexes/bin1_offset, 
+                                    Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/pixels,
+                                    Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/pixels/bin2_id,
+                                    Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/bins, 
+                                    Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/bins/end, 
+                                    Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/bins/start, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/chroms, 
+                                    Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/chroms/name, 
+                                    Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/indexes, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/indexes/bin1_offset, 
+                                    Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/pixels, 
+                                    Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/pixels/bin2_id, 
+                                    Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/bins, 
+                                    Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/bins/end, 
+                                    Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/bins/start, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/chroms, 
+                                    Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/chroms/name, 
+                                    Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/indexes, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/indexes/bin1_offset, 
+                                    Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/pixels, 
+                                    Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/pixels/bin2_id,
+                                    Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/bins,
+                                    Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/bins/chrom, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/bins/end, 
+                                    Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/bins/start, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/chroms,
+                                    Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/chroms/length, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/chroms/name, 
+                                    Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/indexes, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/indexes/bin1_offset, 
+                                    Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/indexes/chrom_offset, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/pixels, 
+                                    Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/pixels/bin1_id, Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/pixels/bin2_id,
+                                    Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz/pixels/count, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz, 
+                                    Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/bins, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/bins/chrom, 
+                                    Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/bins/end, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/bins/start, 
+                                    Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/chroms, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/chroms/length,
+                                    Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/chroms/name, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/indexes, 
+                                    Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/indexes/bin1_offset, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/indexes/chrom_offset,
+                                    Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/pixels, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/pixels/bin1_id,
+                                    Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/pixels/bin2_id, Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz/pixels/count, 
+                                    Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/bins, 
+                                    Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/bins/chrom, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/bins/end,
+                                    Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/bins/start, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/chroms,
+                                    Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/chroms/length, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/chroms/name, 
+                                    Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/indexes, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/indexes/bin1_offset,
+                                    Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/indexes/chrom_offset, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/pixels, 
+                                    Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/pixels/bin1_id, Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/pixels/bin2_id,
+                                    Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz/pixels/count, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz, 
+                                    Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/bins, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/bins/chrom,
+                                    Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/bins/end, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/bins/start,
+                                    Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/chroms, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/chroms/length, 
+                                    Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/chroms/name, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/indexes, 
+                                    Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/indexes/bin1_offset, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/indexes/chrom_offset, 
+                                    Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/pixels, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/pixels/bin1_id, 
+                                    Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/pixels/bin2_id, Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz/pixels/count,
+                                    Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/bins, 
+                                    Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/bins/chrom, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/bins/end,
+                                    Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/bins/start, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/chroms,
+                                    Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/chroms/length, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/chroms/name,
+                                    Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/indexes, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/indexes/bin1_offset, 
+                                    Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/indexes/chrom_offset, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/pixels,
+                                    Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/pixels/bin1_id, Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/pixels/bin2_id, 
+                                    Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz/pixels/count, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz,
+                                    Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/bins, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/bins/chrom, 
+                                    Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/bins/end, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/bins/start,
+                                    Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/chroms, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/chroms/length, 
+                                    Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/chroms/name, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/indexes,
+                                    Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/indexes/bin1_offset, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/indexes/chrom_offset, 
+                                    Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/pixels, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/pixels/bin1_id, 
+                                    Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/pixels/bin2_id, Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz/pixels/count'/></assert_contents>
             </output>
         </test>
     </tests>
@@ -106,7 +176,8 @@
     Number of removed matrices due to too many zero bins (< 0.02 density, within 30000000 relative genomic distance): 610
     2508 samples passed the quality control. Please consider matrices with a low read coverage may be the matrices with a low density and overlap therefore.
 
-4. The scHi-C mcool matrix with the filtered matrices.
+4. The scHi-C scool matrix with the filtered matrices.
+
 For more information about scHiCExplorer please consider our documentation on readthedocs.io_
 
 .. _readthedocs.io: http://schicexplorer.readthedocs.io/
Binary file test-data/scHicConsensusMatrices/consensus_matrix.mcool has changed
Binary file test-data/scHicConsensusMatrices/consensus_matrix.scool has changed
Binary file test-data/scHicCreateBulkMatrix/bulk_matrix.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_TATCCTCT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_AAGGAGTA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_ACTGCATA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_CTAAGCCT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_CTCTCTAT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_GTAAGGAG_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_TATCCTCT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToMCool/Diploid_2_AGGCAGAA_AAGGAGTA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_AAGGAGTA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_ACTGCATA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_CGTCTAAT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_CTAAGCCT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_CTCTCTAT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_GTAAGGAG_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_TATCCTCT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_CGTACTAG_TCTCTCCG_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_TAAGGCGA_AAGGAGTA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_TAAGGCGA_CGTCTAAT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_1_TAAGGCGA_CTAAGCCT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_AAGGAGTA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_ACTGCATA_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_CGTCTAAT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_CTAAGCCT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_CTCTCTAT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_GTAAGGAG_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_TATCCTCT_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_2_AAGAGGCA_TCTCTCCG_R1fastqgz.cool has changed
Binary file test-data/scHicMergeToSCool/Diploid_2_AGGCAGAA_AAGGAGTA_R1fastqgz.cool has changed
Binary file test-data/scHicQualityControl/coverage.png has changed
Binary file test-data/scHicQualityControl/density.png has changed
--- a/test-data/scHicQualityControl/qc_report.txt	Thu Jan 23 16:10:53 2020 -0500
+++ b/test-data/scHicQualityControl/qc_report.txt	Tue Mar 10 15:15:17 2020 -0400
@@ -1,6 +1,6 @@
-# QC report for single-cell Hi-C data generated by scHiCExplorer 1-dev
+# QC report for single-cell Hi-C data generated by scHiCExplorer 4
 scHi-C sample contained 20 cells:
 Number of removed matrices containing bad chromosomes 0
-Number of removed matrices due to low read coverage (< 100000): 8
+Number of removed matrices due to low read coverage (< 100000): 10
 Number of removed matrices due to too many zero bins (< 0.001 density, within 30000000 relative genomic distance): 0
-12 samples passed the quality control. Please consider matrices with a low read coverage may be the matrices with a low density and overlap therefore.
\ No newline at end of file
+10 samples passed the quality control. Please consider matrices with a low read coverage may be the matrices with a low density and overlap therefore.
\ No newline at end of file
Binary file test-data/test_matrix.mcool has changed
Binary file test-data/test_matrix.scool has changed