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1 # MicroBiomML
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3 This repository contains supporting materials for the research article "_Large-scale classification of metagenomic samples: a comparative analysis of classical machine learning techniques vs a novel brain-inspired hyperdimensional computing approach_".
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5 ## Overview
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7 MicroBiomML provides Galaxy tools and pipelines for running classical machine learning (ML) methods on metagenomic datasets sourced from the curatedMetagenomicData R package. In addition, it includes a dedicated Galaxy tool for comparing the performance of traditional ML techniques versus a new brain-inspired hyperdimensional computing (HDC) classification approach.
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9 ## Features
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11 - __Classical Machine Learning Tools__: Scripts and workflows for applying common ML algorithms (e.g., Random Forest, Support Vector Machines, etc.) to metagenomic data.
12 - __HDC Tool__: An implementation of the hyperdimensional computing approach for the classification and feature selection of metagenomic data.
13 - __Galaxy Integration__: All tools and pipelines are wrapped as Galaxy tools for easy execution and reproducibility.
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15 ## Getting Started
16
17 ### Prerequisites
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19 - Galaxy installation
20 - R and the curatedMetagenomicData package
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22 ### Usage
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24 - Install the Galaxy tools from this repository.
25 - Import metagenomic datasets via curatedMetagenomicData.
26 - Run the available ML or HDC pipelines within Galaxy.
27 - Compare results using the dedicated comparison tool.
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29 ## Citation
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31 If you utilize these tools in your research, please cite:
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33 > _Manuscript in preparation_
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35 ## Contact
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37 For questions or further information, contact [Jayadev Joshi](mailto:joshij@ccf.org) and [Fabio Cumbo](mailto:cumbof@ccf.org).
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39 ## License
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41 This work is distributed under the MIT License.