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diff tools/myTools/bin/sfa/data/korkut_2015a/model_3250.sif @ 1:7e5c71b2e71f draft default tip

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author laurenmarazzi
date Wed, 22 Dec 2021 16:00:34 +0000
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--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tools/myTools/bin/sfa/data/korkut_2015a/model_3250.sif	Wed Dec 22 16:00:34 2021 +0000
@@ -0,0 +1,464 @@
+4EBP1pS65	-	G1arrest
+RbpS807	-	ERa
+RbpS807	+	G1arrest
+MEKpS217	+	MAPKpT202
+MEKpS217	-	BIM
+MEKpS217	-	ELK1pS383
+MEKpS217	-	G2arrest
+S6	-	S6pS240
+PAI-1	+	GATA3
+AKTpS473	+	TSC2pT1462
+AMPKpT172	-	RbpS807
+AMPKpT172	+	S6
+b-Catenin	-	b-CateninpS
+b-Catenin	-	IGF1R-beta
+b-Catenin	-	YBIpS102
+b-Catenin	-	SRCpY416
+BIM	-	CyclinD1
+BIM	+	GATA3
+BIM	-	RAD51
+Caveolin	+	IGF1R-beta
+Caveolin	+	SMAD3
+Caveolin	-	G2arrest
+CyclinB1	+	RbpS807
+CyclinB1	+	PLK1
+CyclinD1	+	RbpS807
+CyclinD1	-	BIM
+CyclinD1	-	YAPpS127
+CyclinD1	-	ACCpS79
+IGFBP2	-	AKTpS473
+IGFBP2	+	BIM
+IGFBP2	+	Fibronectin
+IGFBP2	-	mTORpS2448
+IGFBP2	+	cellviab
+p38pT180	-	MAPKpT202
+p38pT180	+	G2M
+p38pT180	-	G1arrest
+p38pT180	-	cellviab
+p53	+	Caveolin
+p53	+	BCL-XL
+p53	+	BCL2
+p53	+	SRC
+p53	+	G1arrest
+p70S6KpT389	-	Fibronectin
+p70S6KpT389	+	S6pS235
+p70S6KpT389	+	S6pS240
+SRCpY527	+	Caspase9
+SRCpY527	+	CHK1pS345
+SRCpY527	-	G2M
+STAT3pY705	-	STAT3
+STAT3pY705	-	STAT5
+STAT3pY705	-	STAT5pY694
+STAT3pY705	-	a-tubulin
+STAT3pY705	+	SRC
+STAT3pY705	-	G2M
+STAT3pY705	-	Sarrest
+TSC2pT1462	-	EGFRV
+YAPpS127	+	IRS1
+YAPpS127	-	p21
+YAPpS127	+	PDK1pS241
+YAPpS127	-	G2arrest
+ACC1	+	PI3Kp85
+ACC1	+	4EBP1pT70
+ACC1	-	Sarrest
+AKTpT308	+	AKTpS473
+AKTpT308	+	GSK3abpS21
+AKTpT308	+	GSKpS9
+AKTpT308	-	BCL-XL
+AKTpT308	+	p21
+AKT	-	MEKpS217
+AKT	+	GSK3abpS21
+AKT	+	TSC2pT1462
+AKT	+	YAPpS127
+AKT	-	YBIpS102
+AKT	-	BCL-XL
+AKT	+	mTORpS2448
+AKT	-	Collagenase
+b-CateninpS	+	PKCa
+b-CateninpS	+	p38
+b-CateninpS	+	G2M
+b-CateninpS	-	Sarrest
+Fibronectin	-	CyclinB1
+Fibronectin	-	SRCpY527
+Fibronectin	+	IGF1R-beta
+Fibronectin	+	IRS1
+Fibronectin	-	PDK1pS241
+Fibronectin	-	IRS1pS307
+Fibronectin	-	Sarrest
+HSP27	-	4EBP1pS65
+HSP27	-	PAI-1
+HSP27	+	SMAD3
+HSP27	+	STAT3
+HSP27	-	G2arrest
+IGF1R-beta	+	b-Catenin
+IGF1R-beta	+	IGFBP2
+IGF1R-beta	+	Fibronectin
+IGF1R-beta	-	IRS1
+IGF1R-beta	+	G2M
+IRS1	-	p38pT180
+IRS1	+	COX2
+IRS1	-	mTORpS2448
+IRS1	-	IRS1pS307
+p27	-	MAPKpT202
+p27	-	GSK3abpS21
+p27	+	IGFBP2
+p27	-	c-Myc
+p27	-	COX2
+p27	-	YBIpS102
+p27	-	G2M
+p27	+	G1arrest
+p27	+	cellviab
+c-Myc	-	p27
+c-Myc	-	SMAD3
+c-Myc	+	STAT5pY694
+c-Myc	+	c-JUNpS73
+c-Myc	-	PKCa
+c-Myc	-	SMAD3pS423
+c-Myc	-	G1arrest
+SMAD3	+	S6
+SMAD3	+	Caveolin
+SMAD3	+	CyclinD1
+SMAD3	+	Fibronectin
+SMAD3	+	c-Myc
+SMAD3	+	cellviab
+STAT3	+	STAT5
+STAT3	+	STAT5pY694
+STAT3	+	p21
+STAT3	+	PDK1pS241
+STAT3	-	G1arrest
+STAT5	-	TSC2pT1462
+STAT5	-	STAT3
+STAT5	-	CHK1pS345
+STAT5	-	p21
+STAT5	-	G2M
+STAT5	+	cellviab
+STAT5pY694	+	STAT3pY705
+STAT5pY694	+	TSC2pT1462
+STAT5pY694	+	AKT
+STAT5pY694	-	GSK3ab
+STAT5pY694	+	STAT6pY641
+STAT5pY694	-	Sarrest
+COX2	-	STAT3
+COX2	-	G1arrest
+PAX2	-	SMAD3
+PAX2	+	CHK2pT68
+PAX2	+	ATMpS1981
+PAX2	+	BAK
+PLK1	+	CyclinB1
+PLK1	-	CHK2pT68
+PLK1	-	G1arrest
+PLK1	+	cellviab
+YBIpS102	-	HSP27
+YBIpS102	+	CHK1pS345
+YBIpS102	-	PDK1pS241
+YBIpS102	-	PKCa
+CHK2pT68	-	PLK1
+CHK2pT68	-	cRAFV
+CHK2pT68	-	SRCpY416
+CHK2pT68	+	G1arrest
+CHK2pT68	+	Sarrest
+Caspase9	+	AKTpS473
+Caspase9	+	b-Catenin
+Caspase9	+	CyclinB1
+Caspase9	+	c-JUNpS73
+Caspase9	-	G2arrest
+Caspase9	+	Sarrest
+a-tubulin	+	COX2
+a-tubulin	-	BAK
+a-tubulin	+	SRCpY416
+a-tubulin	+	IRS1pS307
+a-tubulin	+	p38
+a-tubulin	+	G1arrest
+a-tubulin	+	cellviab
+ATMpS1981	+	PLK1
+ATMpS1981	+	S6pS240
+ATMpS1981	-	bRAF
+ATMpS1981	+	G1arrest
+ATMpS1981	-	Sarrest
+ATMpS1981	-	cellviab
+ATR	-	c-Myc
+ATR	+	CHK2pT68
+ATR	-	ERa
+ATR	-	SRC
+ATR	-	Sarrest
+BAK	-	PAI-1
+BAK	+	PAX2
+BAK	+	ATR
+BAK	+	ERa
+BAK	+	TAZpS89
+BAK	-	G2arrest
+BCL-XL	+	p53
+BCL-XL	-	STAT3
+BCL-XL	+	STAT5pY694
+BCL-XL	+	BCL2
+BCL-XL	-	4EBP1pT70
+BCL-XL	+	G2arrest
+BCL-XL	+	cellviab
+BCL2	-	4EBP1pS65
+BCL2	-	MEKpS217
+BCL2	-	GSKpS9
+BCL2	+	p53
+BCL2	-	p27
+BCL2	+	BCL-XL
+BCL2	+	GATA3
+BCL2	-	GSK3ab
+BCL2	+	STAT6pY641
+BCL2	-	G2M
+BCL2	-	cellviab
+bRAF	+	MEKpS217
+bRAF	-	SRCpY527
+bRAF	+	AKTpT308
+bRAF	+	AKT
+bRAF	+	a-tubulin
+bRAF	+	p38
+bRAF	+	G1arrest
+c-JUNpS73	-	CyclinB1
+c-JUNpS73	-	STAT3pY705
+c-JUNpS73	-	ACC1
+c-JUNpS73	+	c-Myc
+c-JUNpS73	-	4EBP1pT37
+c-JUNpS73	+	G2M
+c-JUNpS73	-	G2arrest
+Casp9cAsp31	-	ATR
+Casp9cAsp31	+	G2M
+CHK1pS345	-	AKTpS473
+CHK1pS345	-	p27
+CHK1pS345	+	YBIpS102
+CHK1pS345	-	p38
+cRAFV	-	IRS1
+cRAFV	-	BCL2
+cRAFV	+	bRAF
+cRAFV	-	ERa
+cRAFV	-	Collagenase
+cRAFV	+	p38
+cRAFV	+	TSC2
+cRAFV	+	G1arrest
+cRAFV	+	G2arrest
+EGFRV	-	ATR
+EGFRV	-	bRAF
+EGFRV	+	Sarrest
+ELK1pS383	+	Caveolin
+ELK1pS383	-	p70S6KpT389
+ELK1pS383	-	GSK3ab
+ELK1pS383	-	G1arrest
+ELK1pS383	+	cellviab
+ERa	-	p70S6KpT389
+ERa	-	4EBP1pT37
+ERa	+	Caspase9
+ERa	+	BAK
+ERa	+	GSK3ab
+GATA3	-	4EBP1pS65
+GATA3	+	Caveolin
+GATA3	-	SMAD3
+GATA3	+	PAX2
+GATA3	+	EGFRV
+GATA3	-	SMAD3pS423
+GATA3	+	G2M
+GATA3	-	G2arrest
+GATA3	-	Sarrest
+GSK3ab	+	b-Catenin
+GSK3ab	+	GSK3abpS21
+GSK3ab	+	GSKpS9
+GSK3ab	-	SRCpY527
+GSK3ab	-	AKTpT308
+GSK3ab	-	Caspase9
+GSK3ab	+	mTORpS2448
+GSK3ab	+	G2M
+mTORpS2448	-	AKTpS473
+mTORpS2448	+	GSKpS9
+mTORpS2448	+	p70S6KpT389
+mTORpS2448	+	AKT
+mTORpS2448	+	CyclinE1
+mTORpS2448	+	p38
+mTORpS2448	-	G1arrest
+p21	-	IRS1
+p21	-	SRCpY416
+p21	+	G2M
+STAT6pY641	-	CyclinE1
+STAT6pY641	-	SMAD3pS423
+STAT6pY641	-	cellviab
+TAZpS89	-	BCL-XL
+TAZpS89	+	XRCC1
+TAZpS89	+	Collagenase
+TAZpS89	+	G1arrest
+XRCC1	-	GSK3abpS21
+XRCC1	+	GATA3
+XRCC1	-	4EBP1pT70
+XRCC1	-	G2M
+XRCC1	+	Sarrest
+PCNA	-	4EBP1pS65
+PCNA	-	S6
+PCNA	+	STAT5pY694
+PCNA	-	p21
+PCNA	+	TAZpS89
+PCNA	-	RAD51
+PCNA	-	TSC2
+PDK1pS241	-	RbpS807
+PDK1pS241	-	a-tubulin
+PDK1pS241	-	BAK
+PDK1pS241	+	G1arrest
+PDK1pS241	+	G2arrest
+PDK1pS241	-	cellviab
+PI3Kp85	-	AMPKpT172
+PI3Kp85	+	GSK3abpS21
+PI3Kp85	+	TSC2pT1462
+PI3Kp85	-	STAT3
+PI3Kp85	+	STAT5
+PI3Kp85	+	COX2
+PI3Kp85	-	ATR
+PI3Kp85	-	CHK1pS345
+PI3Kp85	-	SRCpY416
+PI3Kp85	-	CyclinE1
+PI3Kp85	+	IRS1pS307
+PI3Kp85	+	SRC
+PI3Kp85	-	G2M
+PKCa	-	AKTpS473
+PKCa	-	GSKpS9
+PKCa	-	YAPpS127
+PKCa	+	c-Myc
+PKCa	+	bRAF
+PKCa	+	PDK1pS241
+PKCa	+	SRC
+PKCa	-	G1arrest
+PKCa	-	G2arrest
+RAD51	-	p27
+RAD51	-	PCNA
+RAD51	-	G1arrest
+RAD51	-	G2arrest
+SRCpY416	+	MEKpS217
+SRCpY416	+	AKTpS473
+SRCpY416	-	b-Catenin
+SRCpY416	-	IGF1R-beta
+SRCpY416	-	GATA3
+SRCpY416	+	SRC
+4EBP1pT70	+	S6
+4EBP1pT70	+	ACC1
+4EBP1pT70	+	STAT3
+4EBP1pT70	-	EGFRV
+4EBP1pT70	+	GSK3ab
+4EBP1pT70	+	cellviab
+ACCpS79	+	XRCC1
+ACCpS79	+	G2M
+Collagenase	+	STAT6pY641
+Collagenase	+	PCNA
+Collagenase	+	PKCa
+CyclinE1	-	RbpS807
+CyclinE1	-	AMPKpT172
+CyclinE1	+	CHK2pT68
+IRS1pS307	+	4EBP1pT37
+IRS1pS307	-	p21
+p38	+	p38pT180
+p38	-	STAT3pY705
+p38	+	AKT
+p38	-	STAT5
+p38	+	a-tubulin
+p38	+	ATR
+p38	-	Casp9cAsp31
+p38	-	ELK1pS383
+SMAD3pS423	+	p27
+SMAD3pS423	+	c-Myc
+SMAD3pS423	-	GATA3
+TSC2	-	PAI-1
+TSC2	+	Caveolin
+TSC2	+	TSC2pT1462
+TSC2	-	Casp9cAsp31
+TSC2	+	cRAFV
+TSC2	-	G2arrest
+SRC	-	MEKpS217
+SRC	+	AKTpS473
+SRC	+	b-Catenin
+SRC	-	SRCpY527
+SRC	-	IGF1R-beta
+SRC	+	STAT5
+SRC	+	STAT5pY694
+SRC	+	EGFRV
+SRC	+	PI3Kp85
+SRC	-	SRCpY416
+SRC	+	Collagenase
+SRC	+	G1arrest
+aMEK	+	MAPKpT202
+aMEK	+	MEKpS217
+aMEK	-	Caveolin
+aMEK	+	STAT3pY705
+aMEK	-	STAT5
+aMEK	+	4EBP1pT37
+aMEK	+	bRAF
+aMEK	-	G2M
+aAKT	+	AKTpS473
+aAKT	-	Caveolin
+aAKT	+	AKTpT308
+aAKT	+	HSP27
+aAKT	-	p21
+aAKT	+	G1arrest
+aHDAC	+	AKTpS473
+aHDAC	-	IGFBP2
+aHDAC	+	p53
+aHDAC	+	ACC1
+aHDAC	-	STAT3
+aHDAC	-	COX2
+aHDAC	-	S6pS235
+aHDAC	-	G2arrest
+aMDM2	-	p53
+aMDM2	+	Fibronectin
+aMDM2	+	SRC
+aMDM2	+	cellviab
+aJAK	+	STAT5pY694
+aJAK	-	c-JUNpS73
+aJAK	+	cRAFV
+aJAK	-	PDK1pS241
+aJAK	-	cellviab
+aBRAFm	+	MEKpS217
+aBRAFm	+	ACC1
+aBRAFm	-	AKTpT308
+aBRAFm	+	AKT
+aBRAFm	+	SRCpY416
+aBRAFm	-	G1arrest
+aBRAFm	+	G2arrest
+aBRAFm	+	cellviab
+aPKC	-	PAI-1
+aPKC	+	AKTpS473
+aPKC	-	b-Catenin
+aPKC	+	STAT3pY705
+aPKC	-	IRS1
+aPKC	+	SMAD3
+aPKC	-	COX2
+aPKC	+	p21
+aPKC	-	SRCpY416
+aPKC	-	CyclinE1
+aPKC	+	SMAD3pS423
+aPKC	-	SRC
+aPKC	+	G1arrest
+aSTAT3	+	Caveolin
+aSTAT3	-	STAT5
+aSTAT3	+	STAT5pY694
+aSTAT3	+	cRAFV
+aSTAT3	-	PCNA
+aSTAT3	+	G1arrest
+aSTAT3	+	G2arrest
+amTOR	-	p53
+amTOR	+	p70S6KpT389
+amTOR	-	CyclinE1
+amTOR	-	Sarrest
+aPI3K	+	AKTpS473
+aPI3K	-	CyclinE1
+aCDK4	+	RbpS807
+aCDK4	+	Caveolin
+aCDK4	-	SRCpY527
+aCDK4	+	IRS1pS307
+aCDK4	-	G2arrest
+aCDK4	-	Sarrest
+aCDK4	+	cellviab
+aSRC	+	MEKpS217
+aSRC	+	AKTpS473
+aSRC	-	b-Catenin
+aSRC	+	SRCpY527
+aSRC	+	STAT3pY705
+aSRC	+	AKTpT308
+aSRC	-	IGF1R-beta
+aSRC	-	c-Myc
+aSRC	+	STAT3
+aSRC	+	STAT5
+aSRC	-	CHK2pT68
+aSRC	+	PI3Kp85
+aSRC	+	SRCpY416
+aSRC	-	Sarrest