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diff tools/myTools/bin/sfa/data/zanudo_2015a/network.sif @ 1:7e5c71b2e71f draft default tip

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author laurenmarazzi
date Wed, 22 Dec 2021 16:00:34 +0000
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--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tools/myTools/bin/sfa/data/zanudo_2015a/network.sif	Wed Dec 22 16:00:34 2021 +0000
@@ -0,0 +1,142 @@
+TCR	+	CTLA4
+Stimuli	+	TCR
+CTLA4	-	TCR
+S1P	+	PDGFR
+PDGF	+	PDGFR
+TCR	+	FYN
+IL2RB	+	FYN
+FYN	+	CytoskeletonSignaling
+CD45	+	LCK
+TCR	+	LCK
+IL2RB	+	LCK
+ZAP70	-	LCK
+LCK	+	ZAP70
+FYN	-	ZAP70
+IL2RB	+	GRB2
+ZAP70	+	GRB2
+GRB2	+	PLCG1
+PDGFR	+	PLCG1
+GRB2	+	RAS
+PLCG1	+	RAS
+GAP	-	RAS
+RAS	+	GAP
+PDGFR	+	GAP
+GAP	+	GAP
+IL15	-	GAP
+IL2	-	GAP
+RAS	+	MEK
+PDGFR	+	PI3K
+RAS	+	PI3K
+TPL2	+	NFKB
+PI3K	+	NFKB
+FLIP	+	NFKB
+TRADD	+	NFKB
+IAP	+	NFKB
+PI3K	+	NFAT
+NFKB	+	RANTES
+NFKB	+	IL2
+STAT3	+	IL2
+NFAT	+	IL2
+TBET	-	IL2
+ERK	+	IL2RBT
+TBET	+	IL2RBT
+IL2RBT	+	IL2RB
+IL2	+	IL2RB
+IL15	+	IL2RB
+IL2	+	IL2RAT
+STAT3	+	IL2RAT
+NFKB	+	IL2RAT
+IL2	+	IL2RA
+IL2RAT	+	IL2RA
+IL2RA	-	IL2RA
+IL2RA	+	JAK
+IL2RB	+	JAK
+RANTES	+	JAK
+IFNG	+	JAK
+SOCS	-	JAK
+CD45	-	JAK
+JAK	+	SOCS
+IL2	-	SOCS
+IL15	-	SOCS
+JAK	+	STAT3
+STAT3	+	P27
+STAT3	+	Proliferation
+P27	-	Proliferation
+JAK	+	TBET
+TBET	+	TBET
+ERK	+	CREB
+IFNG	+	CREB
+TBET	+	IFNGT
+STAT3	+	IFNGT
+NFAT	+	IFNGT
+IL2	+	IFNG
+IL15	+	IFNG
+Stimuli	+	IFNG
+IFNGT	+	IFNG
+SMAD	-	IFNG
+P2	-	IFNG
+IFNG	+	P2
+P2	+	P2
+Stimuli2	-	P2
+CREB	+	GZMB
+IFNG	+	GZMB
+TBET	+	GZMB
+TAX	+	TPL2
+PI3K	+	TPL2
+TNF	+	TPL2
+NFKB	+	TNF
+TNF	+	TRADD
+IAP	-	TRADD
+A20	-	TRADD
+STAT3	+	FasL
+NFKB	+	FasL
+NFAT	+	FasL
+ERK	+	FasL
+NFKB	+	FasT
+FasT	+	Fas
+FasL	+	Fas
+sFas	-	Fas
+FasT	+	sFas
+S1P	+	sFas
+Apoptosis	-	sFas
+Fas	+	Ceramide
+S1P	-	Ceramide
+FasT	+	DISC
+Fas	+	DISC
+IL2	+	DISC
+Ceramide	+	DISC
+FLIP	-	DISC
+TRADD	+	Caspase
+GZMB	+	Caspase
+BID	+	Caspase
+IAP	-	Caspase
+DISC	+	Caspase
+NFKB	+	FLIP
+CREB	+	FLIP
+IFNG	+	FLIP
+DISC	-	FLIP
+NFKB	+	A20
+Caspase	+	BID
+GZMB	+	BID
+BclxL	-	BID
+MCL1	-	BID
+NFKB	+	IAP
+BID	-	IAP
+NFKB	+	BclxL
+STAT3	+	BclxL
+BID	-	BclxL
+GZMB	-	BclxL
+DISC	-	BclxL
+IL2RB	+	MCL1
+STAT3	+	MCL1
+NFKB	+	MCL1
+PI3K	+	MCL1
+DISC	-	MCL1
+Caspase	+	Apoptosis
+S1P	+	GPCR
+GPCR	+	SMAD
+PDGFR	+	SPHK1
+SPHK1	+	S1P
+Ceramide	-	S1P
+MEK	+	ERK
+PI3K	+	ERK