diff tools/myTools/bin/sfa/data/pezze_2012/network.sif @ 1:7e5c71b2e71f draft default tip

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author laurenmarazzi
date Wed, 22 Dec 2021 16:00:34 +0000
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--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tools/myTools/bin/sfa/data/pezze_2012/network.sif	Wed Dec 22 16:00:34 2021 +0000
@@ -0,0 +1,30 @@
+I/IGF	+	IR_b
+IR_b	+	PDK2
+IR_b	+	IRS1_PI3K
+IR_b	+	PI3K_variant
+IRS1_PI3K	+	PI3K
+PI3K	+	PIP3
+PIP3	+	PDK1
+PDK1	+	AKT
+AKT	+	AKTP
+PDK2	+	AKTP
+PIP3	+	AKT
+AKT	-	TSC1/2
+AKTP	-	TSC1/2
+TSC1/2	-	Rheb
+mTORC1_pS2448	+	p70S6K
+p70S6K	+	S6
+p70S6K	-	IRS1_PI3K
+p70S6K	+	Protein_Synthesis
+mTORC1_pS2448	+	eIF4E
+eIF4E	+	Protein_Synthesis
+mTORC2	+	AKTP
+PI3K_variant	+	mTORC2
+Rheb	+	mTORC1_Rags
+mTORC1_Rags	+	mTORC1_pS2448
+Amino_Acids	+	mTORC1_Rags
+S6	+	Protein_Synthesis
+AKT	-	PRAS40
+AKTP	-	PRAS40
+PRAS40	-	mTORC1
+mTORC1	+	mTORC1_Rags
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