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RAF	-	TSC1/2
HIF1	+	VEGF
AMPK	+	TSC1/2
CyclinB	-	Rb
ATM/ATR	+	CHK1/2
Hypoxia	-	VHL
PI3K	+	PIP3
Smad/E2F	-	Myc/Max
HIF1	-	BAX
E2F	+	E2F
p53	-	IKK
Cytoc/APAF1	+	Caspase9
p27	-	CyclinA
Mdm2	-	p53
AKT	+	Glut-1
TGFβ	-	Myc/Max
GSK-3	-	Snail
NF-κB	+	Snail
Gli	+	CyclinD
hTERT	+	PI3K
p53/PTEN	-	PTEN
p53	+	p53/PTEN
Myc/Max	-	p27
ATM/ATR	-	Mdm2
AKT	-	p21
Myc/Max	+	Glut-1
Myc/Max	-	p21
Hypoxia	-	PHDs
NF-κB	+	Myc
TNFα	+	TAK1
cdc20	-	CyclinA
TAK1	-	TCF
CyclinB	+	cdc20
GFs	+	RTK
Smad/Miz-1	+	p27
UbcH10	+	cdh1/UbcH10
p21	-	CyclinA
cdh1	+	cdh1/UbcH10
p53	+	p21
mTOR	-	GSK-3
β-catenin	+	TCF
Myc/Max	+	hTERT
Myc/Max	+	PDK1
GSK-3/APC	-	β-catenin
p53	-	CyclinB
WNT	+	PKC
NF1	+	hTERT
IKK	+	NF-κB
Mdm2	+	p53/Mdm2
p53	-	β-catenin
NF-κB	+	GSH
E-cadherin	-	NF-κB
Rb	-	CyclinA
ROS	+	DNA_Damage
HIF1	+	MXI1
HIF1	+	COX412
HIF1	+	TSC1/2
Miz-1	+	Smad/Miz-1
mTOR	+	p70
p90RSK	-	BAD
HIF1	+	p53
TAK1	+	IKK
PIP3	+	PDK1
TCF	+	Myc
E2F	+	E2F/CyclinE
ATM/ATR	+	DNA_Repair
PKC	+	IKK
mTOR	+	HIF1
PKC	+	NF1
Caspase8	+	Cytoc/APAF1
Nutrients	+	RAGS
mTOR	+	IKK
NF-κB	+	Bcl-2
RHEB	+	mTOR
PDK1	+	p70
Smad/Miz-1	-	hTERT
E2F/CyclinE	+	CyclinA
p53	-	hTERT
JNK	+	BAX
CyclinA	-	cdh1
p53	+	BAX
VHL	-	HIF1
Smad	+	Smad/E2F
CyclinB	+	UbcH10
Ras	+	RAF
HIF1	-	Myc
Gli	+	Myc
AKT	-	TSC1/2
PDK1	+	AKT
PIP3	+	NF-κB
TNFα	+	FADD
PHDs	-	IKK
FosJun	+	Myc
RTK	+	Ras
COX412	-	ROS
p53	-	Bcl-2
NF1	-	Ras
Smad/Miz-1	+	p21
CyclinB	-	cdh1
eEF2	-	hTERT
p90RSK	+	eEF2K
Myc	+	Myc/Max
FADD	+	Caspase8
E2F	+	Myc
Myc/Max	+	HIF1
CyclinA	+	UbcH10
TGFβ	+	Smad
TNFα	-	Smad
CyclinA	-	CyclinE
UbcH10	+	UbcH10
PTEN	-	PIP3
BAX	+	Cytoc/APAF1
WNT	+	Dsh
p90RSK	-	GSK-3
CyclinE	-	Rb
cdc20	-	CyclinB
Bcl-2	-	p53
Hypoxia	-	RAGS
MXI1	-	Myc/Max
HIF1	+	Glut-1
FOXO	-	HIF1
CyclinD	-	Rb
CyclinA	-	Rb
AMP/ATP	+	AMPK
p21	-	CyclinD
Smad/Miz-1	+	p15
HIF1	+	hTERT
HIF1	-	BAD
Dsh	-	GSK-3
NF-κB	+	CyclinD
PDK1	+	p90RSK
p21	+	GSH
TCF	+	CyclinD
CyclinA	+	CyclinA
HIF1	+	LDHA
HIF1	+	TGFβ
E2F	+	CyclinE
Rb	-	CyclinE
BAD	-	Bcl-XL
AKT	+	hTERT
Bcl-XL	-	Cytoc/APAF1
AKT	-	Cytoc/APAF1
GSK-3	+	GSK-3/APC
AKT	+	Mdm2
p53	-	HIF1
Snail	+	NF-κB
Nutrients	-	AMP/ATP
HIF1	+	AMPK
p53	+	Cytoc/APAF1
GFs	-	AMPK
Myc/Max	+	LDHA
Hypoxia	+	HIF1
ROS	-	PHDs
hTERT	-	p21
FosJun	+	CyclinD
Myc/Max	+	CyclinD
p27	-	CyclinE
Myc/Max	-	Miz-1
TGFβ	+	JNK
TSC1/2	-	RHEB
cdh1	-	cdc20
BAX	-	Bcl-2
RAGS	+	mTOR
Ras	+	PI3K
cdc20	+	cdh1
RAF	-	BAD
Miz-1	+	p15
CyclinD	-	p27
BAD	-	Bcl-2
CHK1/2	+	p53
Mdm2	-	Rb
AKT	-	p27
cdc20	+	UbcH10
cdh1	-	CyclinB
GSH	-	ROS
p27	-	CyclinB
ERK-1/2	-	TSC1/2
Smad/Miz-1	+	Snail
Rb	-	E2F
Ras	+	p14ARF
ERK-1/2	+	p90RSK
p21	-	CyclinE
RTK	+	PKC
Bcl-2	-	Cytoc/APAF1
CyclinE	+	E2F/CyclinE
Smad	+	Smad/Miz-1
Bcl-2	-	BAX
PTEN	-	APC
ROS	-	VHL
DNA_Damage	+	ATM/ATR
Caspase8	+	Apoptosis
AKT	-	GSK-3
BaK	+	Cytoc/APAF1
p90RSK	-	TSC1/2
Myc/Max	+	GSH
E2F	+	p14ARF
NF-κB	-	E-cadherin
AMPK	-	mTOR
CyclinA	-	E2F
Gli	+	WNT
Caspase8	+	BaK
HIF1	+	PDK1
NF-κB	+	Slug
p53	+	Mdm2
GSK-3	-	CyclinD
HIF1	+	p27
CyclinB	-	p27
eEF2K	-	eEF2
p14ARF	-	Mdm2
APC	+	GSK-3/APC
p53	-	Snail
HIF1	+	p21
PHDs	-	HIF1
p53	-	WNT
Myc/Max	+	VEGF
Caspase9	+	Apoptosis
p70	+	eEF2K
NF-κB	+	hTERT
PKC	+	RAF
p53/Mdm2	-	Slug
p15	-	CyclinD
ERK-1/2	+	FosJun
p53	+	p53/Mdm2
Snail	-	E-cadherin
FOXO	-	CyclinD
AKT	-	BAD
PIP3	+	AKT
Myc/Max	+	p14ARF
LDHA	+	Acid_Lactic
p21	-	CyclinB
Max	+	Myc/Max
p53	-	Bcl-XL
cdh1/UbcH10	+	CyclinA
AKT	+	mTOR
ATM/ATR	+	AMPK
Mutagen	+	DNA_Damage
TCF	+	Slug
CyclinB	-	E2F
Slug	-	E-cadherin
p53	+	TSC1/2
AKT	+	IKK
CyclinA	-	p27
cdh1	-	UbcH10
p27	-	CyclinD
JNK	+	FosJun
AKT	-	FOXO
PTEN	+	p53/PTEN
ERK-1/2	+	Myc
RAF	+	ERK-1/2
CyclinA	+	Proliferation
CyclinB	+	Proliferation
CyclinD	+	Proliferation
CyclinE	+	Proliferation