Mercurial > repos > miller-lab > genome_diversity
diff offspring_heterozygosity_pedigree.py @ 31:a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
author | Richard Burhans <burhans@bx.psu.edu> |
---|---|
date | Fri, 20 Sep 2013 13:25:27 -0400 |
parents | |
children |
line wrap: on
line diff
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/offspring_heterozygosity_pedigree.py Fri Sep 20 13:25:27 2013 -0400 @@ -0,0 +1,58 @@ +#!/usr/bin/env python + +import sys +import gd_util + +from Population import Population + +def load_and_check_pop(file, total_pop, name): + p = Population() + p.from_population_file(file) + if not total_pop.is_superset(p): + gd_util.die('There is an individual in the {0} that is not in the SNP table'.format(name)) + return p + +def append_breeders_from_file(the_list, filename, kind): + with open(filename) as fh: + for line in fh: + elems = line.split() + breeder = elems[0].rstrip('\r\n') + the_list.append('{0}:{1}'.format(kind, breeder)) + +################################################################################ + +if len(sys.argv) != 9: + gd_util.die('Usage') + +input, input_type, pedigree, ind_arg, founders, b1_input, b2_input, output = sys.argv[1:] + +p_total = Population() +p_total.from_wrapped_dict(ind_arg) + +f1 = load_and_check_pop(founders, p_total, 'founders') + +################################################################################ + +prog = 'offspring_heterozygosity2' + +args = [ prog ] +args.append(input) # a Galaxy SNP table +args.append(pedigree) # a pedigree, where the SNP table is for the founders + +for tag in f1.tag_list(): + column, name = tag.split(':') + if type == 'gd_genotype': + column = int(column) - 2 + tag = 'founder:{0}:{1}'.format(column, name) + args.append(tag) + +append_breeders_from_file(args, b1_input, 0) +append_breeders_from_file(args, b2_input, 1) + +with open(output, 'w') as fh: + gd_util.run_program(prog, args, stdout=fh) + +################################################################################ + +sys.exit(0) +