# HG changeset patch # User mrvollger # Date 1418448303 18000 # Node ID 3854046fe103ec9c559cf238a189c1821934045e # Parent ef6832a559e9b12dcf0252d5efd9d56ecdad851f Uploaded diff -r ef6832a559e9 -r 3854046fe103 trtr.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/trtr.xml Sat Dec 13 00:25:03 2014 -0500 @@ -0,0 +1,43 @@ + + + trtr + + + Trim Reads of Tandem Repeat in a fastq file. + + + trtr $input $max_repeat $aggressive > $output + + + + + + + + + + + + + + + + + + + + + + + + +This tool removes tandem repeats from ends of unaligned sequencing reads (leaving one copy). This prevents reads that don't span the repeated region from overlapping and leading to innaccurate SNPs calls. + +The maximimum repeat length is adjustable (use 1 to trim only homopolymers). + +The "aggressive" option should not be touched in general. Setting to 0 will prevent the program from trimming to exactly 1 copy of the repeat, instead leaving between 1 and 2 copies. + +This could also be a useful first step before assembly. More testing needs to be done. + + +