# HG changeset patch # User mrvollger # Date 1418975065 18000 # Node ID c06c920fb4208bcdf5ef82c1c274785b087ad38b # Parent e9036c9aade98eb5d79d45fa14d95ced23fd4605 Uploaded diff -r e9036c9aade9 -r c06c920fb420 trtr.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/trtr.xml Fri Dec 19 02:44:25 2014 -0500 @@ -0,0 +1,43 @@ + + + trtr + + + Trim Reads of Tandem Repeat in a fastq file. + + + trtr $input $max_repeat $aggressive > $output + + + + + + + + + + + + + + + + + + + + + + + + +This tool removes tandem repeats from ends of unaligned sequencing reads (leaving one copy). This prevents reads that don't span the repeated region from overlapping and leading to innaccurate SNPs calls. + +The maximimum repeat length is adjustable (use 1 to trim only homopolymers). + +The "aggressive" option should not be touched in general. Setting to 0 will prevent the program from trimming to exactly 1 copy of the repeat, instead leaving between 1 and 2 copies. + +This could also be a useful first step before assembly. More testing needs to be done. + + +