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view test-data/Nodes_biogrid_from_Wilson-foie-souris_geneID.tsv @ 5:ba96ca3496a2 draft default tip
"planemo upload commit c9a32e920aae2bc186183611bc0abb2040e106f3"
| author | proteore |
|---|---|
| date | Thu, 06 Feb 2020 08:28:04 -0500 |
| parents | 99f6a94c1ade |
| children |
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Entrez gene ID Official Symbol Interactor Present in user input ids ID present in Biogrid Mouse Pathway 143 NA False True NA 197 NA False True NA 219 NA False True NA 369 NA False True NA 514 NA False True NA 596 BCL2 False True NA 598 BCL2L1 False True NA 682 NA False True NA 701 NA False True NA 722 NA False True NA 741 NA False True NA 790 NA False True NA 988 NA False True NA 991 NA False True NA 996 CDC27 False True NA 1191 NA False True NA 1287 NA False True NA 1373 NA False True NA 1431 NA False True NA 1613 DAPK3 False True NA 1639 NA False True NA 1660 DHX9 False True NA 1665 NA False True NA 1778 NA False True NA 1781 NA False True NA 1783 NA False True NA 1789 NA False True NA 1836 NA False True NA 2010 NA False True NA 2305 NA False True NA 2628 NA False True NA 2803 NA False True NA 2817 NA False True NA 2934 NA False True NA 3020 H3F3A False True NA 3178 NA False True NA 3181 NA False True NA 3182 NA False True NA 3183 NA False True NA 3189 NA False True NA 3301 NA False True NA 3308 HSPA4 False True NA 3312 NA False True NA 3418 NA False True NA 3614 NA False True NA 3643 INSR False True NA 3672 NA False True NA 3703 NA False True NA 3708 NA False True NA 3930 NA False True NA 4085 NA False True NA 4170 NA False True NA 4216 NA False True NA 4221 NA False True NA 4245 NA False True NA 4292 NA False True NA 4478 NA False True NA 4670 NA False True NA 4673 NA False True NA 4809 NA False True NA 5091 NA False True NA 5094 NA False True NA 5119 NA False True NA 5211 NA False True NA 5214 NA False True NA 5226 NA False True NA 5356 NA False True NA 5422 NA False True NA 5557 NA False True NA 5558 NA False True NA 5709 NA False True NA 5888 NA False True NA 5903 NA False True NA 5905 NA False True NA 5921 RASA1 False True NA 5929 NA False True NA 5954 NA False True NA 5962 NA False True NA 5987 NA False True NA 6168 NA False True NA 6294 NA False True NA 6500 SKP1 False True NA 6548 NA False True NA 6627 NA False True NA 6628 NA False True NA 6629 NA False True NA 6632 NA False True NA 6633 NA False True NA 6634 NA False True NA 6635 NA False True NA 6636 NA False True NA 6637 NA False True NA 6836 NA False True NA 6921 NA False True NA 6990 NA False True NA 7175 NA False True NA 7283 NA False True NA 7756 NA False True NA 7862 NA False True NA 8175 NA False True NA 8379 NA False True NA 8402 NA False True NA 8453 CUL2 False True NA 8473 NA False True NA 8480 NA False True NA 8502 NA False True NA 8607 NA False True NA 8697 NA False True NA 8881 CDC16 False True NA 9092 NA False True NA 9128 NA False True NA 9129 NA False True NA 9343 NA False True NA 9371 NA False True NA 9410 NA False True NA 9416 NA False True NA 9584 NA False True NA 9587 NA False True NA 9667 NA False True NA 9688 NA False True NA 9696 NA False True NA 9716 NA False True NA 9774 NA False True NA 9782 NA False True NA 9785 NA False True NA 9852 NA False True NA 9879 NA False True NA 9931 NA False True NA 9939 NA False True NA 9961 NA False True NA 9967 NA False True NA 9987 NA False True NA 10042 NA False True NA 10078 NA False True NA 10112 NA False True NA 10121 NA False True NA 10197 NA False True NA 10236 NA False True NA 10237 NA False True NA 10262 NA False True NA 10284 SAP18 False True NA 10286 NA False True NA 10291 NA False True NA 10381 NA False True NA 10421 NA False True NA 10426 NA False True NA 10432 NA False True NA 10450 NA False True NA 10465 NA False True NA 10491 NA False True NA 10513 NA False True NA 10523 NA False True NA 10540 NA False True NA 10557 NA False True NA 10558 NA False True NA 10594 NA False True NA 10615 NA False True NA 10627 NA False True NA 10632 NA False True NA 10657 NA False True NA 10682 NA False True NA 10713 NA False True NA 10763 NA False True NA 10807 NA False True NA 10844 NA False True NA 10856 NA False True NA 10946 NA False True NA 10949 NA False True NA 10992 NA False True NA 11017 NA False True NA 11102 NA False True NA 11164 NA False True NA 11193 NA False True NA 11222 NA False True NA 11234 NA False True NA 11243 NA False True NA 11315 NA False True NA 11319 NA False True NA 11325 NA False True NA 11636 NA True False Interconversion of nucleotide di- and triphosphates 11677 NA True False Pregnenolone biosynthesis 11766 Ap1g2 True True Lysosome Vesicle Biogenesis 11852 NA True False GPVI-mediated activation cascade;Rho GTPase cycle;G alpha (12/13) signalling events;Sema4D induced cell migration and growth-cone collapse;RHO GTPases activate PKNs;RHO GTPases activate CIT;RHO GTPases Activate ROCKs;RHO GTPases Activate Formins 11853 NA True False Rho GTPase cycle;G alpha (12/13) signalling events;Sema4D induced cell migration and growth-cone collapse;RHO GTPases activate PKNs;RHO GTPases activate CIT;RHO GTPases Activate ROCKs;RHO GTPases Activate Formins 12018 Bak1 False True Activation and oligomerization of BAK protein;Release of apoptotic factors from the mitochondria 12028 Bax True True Release of apoptotic factors from the mitochondria;Activation, translocation and oligomerization of BAX;TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 12043 Bcl2 False True Activation of BAD and translocation to mitochondria ;BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members;The NLRP1 inflammasome 12048 Bcl2l1 False True BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members;The NLRP1 inflammasome 12050 Bcl2l2 False True NA 12234 Btrc False True Activation of NF-kappaB in B cells;Prolactin receptor signaling;SCF-beta-TrCP mediated degradation of Emi1;Degradation of beta-catenin by the destruction complex;Downstream TCR signaling;Regulation of PLK1 Activity at G2/M Transition;FCERI mediated NF-kB activation;Deactivation of the beta-catenin transactivating complex;Dectin-1 mediated noncanonical NF-kB signaling;CLEC7A (Dectin-1) signaling;NIK-->noncanonical NF-kB signaling;MAP3K8 (TPL2)-dependent MAPK1/3 activation;Neddylation;Interleukin-1 signaling;Antigen processing: Ubiquitination & Proteasome degradation 12293 NA True False NA 12306 Anxa2 False True Neutrophil degranulation;Dissolution of Fibrin Clot 12330 Canx False True MHC class II antigen presentation;Interleukin-35 Signalling;Calnexin/calreticulin cycle;Interleukin-27 signaling;Antigen Presentation: Folding, assembly and peptide loading of class I MHC 12332 NA True False NA 12387 Ctnnb1 False True Degradation of beta-catenin by the destruction complex;Beta-catenin phosphorylation cascade;TCF dependent signaling in response to WNT;Formation of the beta-catenin:TCF transactivating complex;LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production;Apoptotic cleavage of cell adhesion proteins;CDO in myogenesis;Deactivation of the beta-catenin transactivating complex;Ca2+ pathway;Adherens junctions interactions;Disassembly of the destruction complex and recruitment of AXIN to the membrane;VEGFR2 mediated vascular permeability;RHO GTPases activate IQGAPs;RUNX3 regulates WNT signaling 12490 NA True False Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 12798 NA True False Neutrophil degranulation 12856 NA True False NA 12857 NA False True NA 13046 Celf1 True True NA 13086 NA True False Fatty acids;Xenobiotics;CYP2E1 reactions;Aflatoxin activation and detoxification 13118 NA True False Fatty acids;Miscellaneous substrates;Eicosanoids;Synthesis of Leukotrienes (LT) and Eoxins (EX);Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) 13179 NA True False Degradation of the extracellular matrix;A tetrasaccharide linker sequence is required for GAG synthesis;Chondroitin sulfate biosynthesis;Dermatan sulfate biosynthesis;CS/DS degradation;ECM proteoglycans 13204 NA True False mRNA Splicing - Major Pathway 13206 Ddx4 False True NA 13211 NA True False RIP-mediated NFkB activation via ZBP1;DEx/H-box helicases activate type I IFN and inflammatory cytokines production ;mRNA Splicing - Major Pathway 13489 Drd2 False True Dopamine receptors;G alpha (i) signalling events 13821 Epb4.1l1 True True Trafficking of AMPA receptors;Neurexins and neuroligins 13858 Eps15 False True EGFR downregulation;Negative regulation of MET activity;Cargo recognition for clathrin-mediated endocytosis;Clathrin-mediated endocytosis 14105 NA True False NA 14114 NA True False Molecules associated with elastic fibres 14548 NA True False Mitochondrial translation elongation;Mitochondrial translation termination 14864 NA True False NA 14999 NA True False MHC class II antigen presentation 15463 Agfg1 True True Cargo recognition for clathrin-mediated endocytosis;Clathrin-mediated endocytosis 16069 NA True False Cell surface interactions at the vascular wall;Scavenging of heme from plasma 16362 Irf1 False True NA 16414 Itgb2 True True Toll Like Receptor 4 (TLR4) Cascade;Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell;Cell surface interactions at the vascular wall;Integrin cell surface interactions;Neutrophil degranulation 16852 NA True False Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs);Post-translational protein phosphorylation 17063 NA True False O-linked glycosylation of mucins;Termination of O-glycan biosynthesis 17068 NA True False Post-translational modification: synthesis of GPI-anchored proteins 17075 NA True False Cell surface interactions at the vascular wall 17079 NA True False Toll Like Receptor 4 (TLR4) Cascade 17149 Magoh True True Cleavage of Growing Transcript in the Termination Region ;Transport of Mature mRNA derived from an Intron-Containing Transcript;mRNA Splicing - Major Pathway;mRNA 3'-end processing 17184 NA True False NA 17304 NA True False Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs);Post-translational protein phosphorylation 17476 Mpeg1 True True NA 17748 Mt1 True True NA 17750 NA True False NA 17931 Ppp1r12a True True Regulation of PLK1 Activity at G2/M Transition;RHO GTPases activate PKNs;RHO GTPases activate PAKs 18054 NA True False NA 18104 NA True False Regulation of ornithine decarboxylase (ODC) 18627 Per2 False True NA 19039 Lgals3bp True True Platelet degranulation 19047 Ppp1cc False True Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal;Separation of Sister Chromatids;Resolution of Sister Chromatid Cohesion;RHO GTPases Activate Formins;Mitotic Prometaphase 19052 Ppp2ca False True Inhibition of replication initiation of damaged DNA by RB1/E2F1;Spry regulation of FGF signaling;Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal;DARPP-32 events;Degradation of beta-catenin by the destruction complex;Beta-catenin phosphorylation cascade;ERK/MAPK targets;ERKs are inactivated;Separation of Sister Chromatids;Resolution of Sister Chromatid Cohesion;CTLA4 inhibitory signaling;Platelet sensitization by LDL;Disassembly of the destruction complex and recruitment of AXIN to the membrane;RHO GTPases Activate Formins;RAF activation;Regulation of TP53 Degradation;PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling;Mitotic Prometaphase;Cyclin D associated events in G1;Cyclin A/B1/B2 associated events during G2/M transition;Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 19184 Psmc5 False True Autodegradation of Cdh1 by Cdh1:APC/C;UCH proteinases;Ub-specific processing proteases;CDT1 association with the CDC6:ORC:origin complex;Neddylation 19192 Psme3 True True Autodegradation of Cdh1 by Cdh1:APC/C;UCH proteinases;Ub-specific processing proteases;CDT1 association with the CDC6:ORC:origin complex;Neddylation 19225 Ptgs2 False True Nicotinamide salvaging;Synthesis of 15-eicosatetraenoic acid derivatives;Synthesis of Prostaglandins (PG) and Thromboxanes (TX);Biosynthesis of EPA-derived SPMs;Biosynthesis of DPAn-3 SPMs;Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives 19240 NA True False NA 19383 NA True False NA 19656 NA True False NA 19659 Rbp1 True True The canonical retinoid cycle in rods (twilight vision);Retinoid metabolism and transport 19766 Ripk1 False True Caspase activation via Death Receptors in the presence of ligand;TRIF-mediated programmed cell death;TRP channels;Regulation by c-FLIP;RIPK1-mediated regulated necrosis;CASP8 activity is inhibited;TNFR1-induced proapoptotic signaling;Regulation of TNFR1 signaling;TNFR1-induced NFkappaB signaling pathway;Ub-specific processing proteases;Ovarian tumor domain proteases;Dimerization of procaspase-8;TNF signaling;IKK complex recruitment mediated by RIP1 20194 S100a10 False True Dissolution of Fibrin Clot 20218 Khdrbs1 True True PTK6 Regulates Proteins Involved in RNA Processing 20310 NA False True Chemokine receptors bind chemokines;G alpha (i) signalling events;Neutrophil degranulation 20351 Sema4a False True Other semaphorin interactions 20384 NA True False Cleavage of Growing Transcript in the Termination Region ;Transport of Mature mRNA derived from an Intron-Containing Transcript;mRNA Splicing - Major Pathway;mRNA 3'-end processing 20462 NA True False mRNA Splicing - Major Pathway 20479 Vps4b False True Endosomal Sorting Complex Required For Transport (ESCRT) 20617 Snca False True NA 20630 Snrpc True True mRNA Splicing - Major Pathway 20719 NA True False Neutrophil degranulation;Dissolution of Fibrin Clot 20753 NA True False NA 20773 Sptlc2 True True Sphingolipid de novo biosynthesis 20860 NA True False Cytosolic sulfonation of small molecules 21681 NA True False NA 21926 Tnf False True TNFR1-induced proapoptotic signaling;Regulation of TNFR1 signaling;TNFR1-induced NFkappaB signaling pathway;TNFR1-mediated ceramide production;TNFR2 non-canonical NF-kB pathway;TNF signaling 22192 Ube2m False True TGF-beta receptor signaling activates SMADs;Dectin-1 mediated noncanonical NF-kB signaling;NIK-->noncanonical NF-kB signaling;Neddylation;Antigen processing: Ubiquitination & Proteasome degradation 22218 Sumo1 True True SUMO is conjugated to E1 (UBA2:SAE1);SUMO is transferred from E1 to E2 (UBE2I, UBC9);SUMO is proteolytically processed;SUMOylation of DNA damage response and repair proteins;SUMOylation of transcription factors;SUMOylation of ubiquitinylation proteins;SUMOylation of transcription cofactors;SUMOylation of SUMOylation proteins;SUMOylation of intracellular receptors;SUMOylation of chromatin organization proteins;SUMOylation of RNA binding proteins;SUMOylation of DNA replication proteins;SUMOylation of DNA methylation proteins;SUMOylation of immune response proteins;Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks;Nonhomologous End-Joining (NHEJ);Processing of DNA double-strand break ends;Formation of Incision Complex in GG-NER;G2/M DNA damage checkpoint;Regulation of IFNG signaling;Negative regulation of activity of TFAP2 (AP-2) family transcription factors 22225 NA False True Ub-specific processing proteases;Synthesis of active ubiquitin: roles of E1 and E2 enzymes 22240 NA True False CRMPs in Sema3A signaling 22323 Vasp True True Signaling by ROBO receptors;Cell-extracellular matrix interactions 22346 Vhl False True Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha;SUMOylation of ubiquitinylation proteins;Neddylation;Antigen processing: Ubiquitination & Proteasome degradation 22350 Ezr True True Netrin-1 signaling;Recycling pathway of L1 22431 NA False True NA 22824 NA False True NA 22826 NA False True NA 22913 NA False True NA 22938 SNW1 False True NA 22944 NA False True NA 22974 NA False True NA 22985 NA False True NA 23020 NA False True NA 23022 NA False True NA 23060 NA False True NA 23077 NA False True NA 23154 NA False True NA 23191 NA False True NA 23193 NA False True NA 23196 NA False True NA 23304 NA False True NA 23350 NA False True NA 23450 NA False True NA 23451 NA False True NA 23513 NA False True NA 23524 NA False True NA 23528 NA False True NA 23548 NA False True NA 23633 NA False True NA 23649 NA False True NA 23753 NA False True NA 23770 NA False True NA 24144 NA False True NA 24148 NA False True NA 25804 NA False True NA 25814 NA False True NA 25864 NA False True NA 25945 NA False True NA 25949 NA False True NA 25980 NA False True NA 25998 NA False True NA 26092 NA False True NA 26121 NA False True NA 26153 NA False True NA 26240 NA False True NA 26509 MYOF False True NA 26754 Cops5 False True DNA Damage Recognition in GG-NER;Formation of TC-NER Pre-Incision Complex;Cargo recognition for clathrin-mediated endocytosis;Neddylation 26965 Cul1 False True Activation of NF-kappaB in B cells;Prolactin receptor signaling;SCF-beta-TrCP mediated degradation of Emi1;SCF(Skp2)-mediated degradation of p27/p21;Degradation of beta-catenin by the destruction complex;Downstream TCR signaling;Regulation of PLK1 Activity at G2/M Transition;FCERI mediated NF-kB activation;Dectin-1 mediated noncanonical NF-kB signaling;CLEC7A (Dectin-1) signaling;NIK-->noncanonical NF-kB signaling;MAP3K8 (TPL2)-dependent MAPK1/3 activation;Orc1 removal from chromatin;Cyclin D associated events in G1;FBXL7 down-regulates AURKA during mitotic entry and in early mitosis;Regulation of RUNX2 expression and activity;Neddylation;Interleukin-1 signaling;Iron uptake and transport;Antigen processing: Ubiquitination & Proteasome degradation 27053 NA True False Amino acid synthesis and interconversion (transamination) 27154 NA False True NA 27332 NA False True NA 27336 NA False True NA 27339 NA False True NA 28000 Prpf19 True True Formation of TC-NER Pre-Incision Complex;Dual incision in TC-NER;Gap-filling DNA repair synthesis and ligation in TC-NER;mRNA Splicing - Major Pathway 29927 NA False True NA 29945 NA False True NA 30934 NA True False Cargo recognition for clathrin-mediated endocytosis 41744 NA False True NA 50773 NA False True Purine catabolism 50873 Park2 False True Pink/Parkin Mediated Mitophagy;Josephin domain DUBs;Antigen processing: Ubiquitination & Proteasome degradation 50915 NA True False Tie2 Signaling 51071 NA False True NA 51116 NA False True NA 51143 NA False True NA 51256 NA False True NA 51319 NA False True NA 51340 NA False True NA 51433 NA False True NA 51434 NA False True NA 51503 NA False True NA 51547 NA False True NA 51639 NA False True NA 51645 NA False True NA 51647 NA False True NA 51652 NA False True NA 51691 NA False True NA 51729 NA False True NA 51759 NA False True NA 53379 Hnrnpa2b1 True True mRNA Splicing - Major Pathway 53380 Psmd10 False True NA 53415 NA True False NA 54148 NA False True NA 54401 Ywhab False True Activation of BAD and translocation to mitochondria ;Translocation of SLC2A4 (GLUT4) to the plasma membrane;mTOR signalling;mTORC1-mediated signalling;Signaling by Hippo;Rap1 signalling;Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA;RHO GTPases activate PKNs;TP53 Regulates Metabolic Genes;RAF activation;MAP2K and MAPK activation;Negative regulation of MAPK pathway;Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex;Regulation of localization of FOXO transcription factors 55110 NA False True NA 55112 NA False True NA 55173 NA False True NA 55346 NA False True NA 55364 NA False True NA 55527 NA False True NA 55536 NA False True NA 55607 NA False True NA 55612 NA False True NA 55614 NA False True NA 55622 NA False True NA 55666 NA False True NA 55692 NA False True NA 55706 NA False True NA 55813 NA False True NA 55837 NA False True NA 55929 NA False True NA 56086 Set False True Condensation of Prophase Chromosomes;HuR (ELAVL1) binds and stabilizes mRNA 56150 Mad2l1 True True Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components;Inactivation of APC/C via direct inhibition of the APC/C complex;Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal;Cdc20:Phospho-APC/C mediated degradation of Cyclin A;APC/C:Cdc20 mediated degradation of mitotic proteins;APC-Cdc20 mediated degradation of Nek2A;Separation of Sister Chromatids;Resolution of Sister Chromatid Cohesion;RHO GTPases Activate Formins;Mitotic Prometaphase 56215 NA True False Apoptotic cleavage of cellular proteins 56252 NA False True NA 56351 Ptges3 False True Synthesis of Prostaglandins (PG) and Thromboxanes (TX);HSP90 chaperone cycle for steroid hormone receptors (SHR);HSF1 activation;Attenuation phase;Aryl hydrocarbon receptor signalling;ESR-mediated signaling;Estrogen-dependent gene expression 56647 NA False True NA 56704 NA False True NA 56705 Ranbp9 True True L1CAM interactions;RAF/MAP kinase cascade;MET activates RAS signaling 56857 NA True False Gluconeogenesis 56886 NA False True NA 56905 NA False True NA 56949 NA False True NA 57479 NA False True NA 57576 NA False True NA 58493 NA False True NA 60386 NA False True NA 60625 NA False True NA 64062 NA False True NA 64080 NA False True NA 64146 NA False True NA 64175 NA False True NA 64682 NA False True NA 64978 NA False True NA 65964 NA True False NA 66120 NA True False NA 66144 NA True False ROS, RNS production in phagocytes;Insulin receptor recycling;Transferrin endocytosis and recycling;Ion channel transport 66395 Ahnak True True NA 66585 NA True False mRNA Splicing - Major Pathway;mRNA Splicing - Minor Pathway 66830 Nacc1 False True NA 67040 NA True False SUMOylation of transcription cofactors 67068 Dynlrb1 True True Intraflagellar transport 67092 Gatm True True Creatine metabolism 67103 NA True False NA 67144 NA True False NA 67465 Sf3a1 True True mRNA Splicing - Major Pathway 67657 NA True False NA 67938 NA True False Smooth Muscle Contraction;RHO GTPases activate PAKs 67996 NA True False Cleavage of Growing Transcript in the Termination Region ;Transport of Mature mRNA derived from an Intron-Containing Transcript;mRNA Splicing - Major Pathway;mRNA Splicing - Minor Pathway;mRNA 3'-end processing 68087 NA True False NA 68153 Gtf2e2 False True RNA Polymerase II Pre-transcription Events;RNA polymerase II transcribes snRNA genes;RNA Polymerase II Promoter Escape;RNA Polymerase II Transcription Pre-Initiation And Promoter Opening;RNA Polymerase II Transcription Initiation;RNA Polymerase II Transcription Initiation And Promoter Clearance 68219 NA True False Cleavage of Growing Transcript in the Termination Region ;mRNA Splicing - Major Pathway;mRNA 3'-end processing;Processing of Intronless Pre-mRNAs 68441 NA True False Macroautophagy;mTOR signalling;mTORC1-mediated signalling;Energy dependent regulation of mTOR by LKB1-AMPK;TP53 Regulates Metabolic Genes;E3 ubiquitin ligases ubiquitinate target proteins;Regulation of PTEN gene transcription 68556 NA True False Pyrimidine salvage 68565 NA True False Mitochondrial translation elongation;Mitochondrial translation termination 68693 NA True False NA 68953 Chmp2a True True Macroautophagy;Lysosome Vesicle Biogenesis;Endosomal Sorting Complex Required For Transport (ESCRT) 68981 NA True False mRNA Splicing - Major Pathway 69694 NA True False NA 69787 NA True False NA 71514 Sfpq True True PTK6 Regulates Proteins Involved in RNA Processing 71660 NA True False Platelet degranulation 71733 NA True False NA 72040 NA True False NA 72082 NA True False NA 72303 NA True False Xenobiotics;CYP2E1 reactions;Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET);Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE);Biosynthesis of maresin-like SPMs 72657 NA True False NA 72787 Ndc1 True True Transport of Mature mRNA derived from an Intron-Containing Transcript;SUMOylation of DNA damage response and repair proteins;Nuclear Pore Complex (NPC) Disassembly;Regulation of HSF1-mediated heat shock response;SUMOylation of DNA replication proteins 74122 NA True False NA 74125 NA True False Neutrophil degranulation 74326 NA True False mRNA Splicing - Major Pathway 74551 NA True False Gluconeogenesis 74558 NA True False NA 74568 NA True False TRP channels;RIPK1-mediated regulated necrosis 75062 NA True False mRNA Splicing - Major Pathway 76281 Tax1bp3 True True RHO GTPases Activate Rhotekin and Rhophilins 76650 NA True False NA 77106 NA True False NA 77134 Hnrnpa0 True True mRNA Splicing - Major Pathway 79631 NA False True NA 79709 NA False True NA 79780 NA False True NA 79922 NA False True NA 79939 NA False True NA 79991 NA False True NA 80005 NA False True NA 80006 NA False True NA 80097 NA False True NA 80184 NA False True NA 80349 NA False True NA 80728 NA False True NA 80829 NA False True NA 81898 NA True False B-WICH complex positively regulates rRNA expression;mRNA Splicing - Major Pathway;mRNA Splicing - Minor Pathway 83443 NA False True NA 83696 NA False True NA 83701 NA True False RNA polymerase II transcribes snRNA genes;mRNA Splicing - Major Pathway 84131 NA False True NA 84168 NA False True NA 84256 NA False True NA 84305 NA False True NA 84844 NA False True NA 84926 NA False True NA 84991 NA False True NA 85378 NA False True NA 89891 NA False True NA 90293 NA False True NA 90324 NA False True NA 90417 NA False True NA 90480 GADD45GIP1 False True NA 92017 NA False True NA 93349 NA False True NA 94090 Trim9 False True Antigen processing: Ubiquitination & Proteasome degradation 94104 NA False True NA 94332 NA False True Adherens junctions interactions;Nectin/Necl trans heterodimerization 96764 NA False True NA 98415 NA True False NA 98932 NA False True NA 99889 NA True False NA 100317 NA True False NA 100535 NA False True NA 102502 NA True False NA 104759 NA True False Synthesis of IP3 and IP4 in the cytosol;Role of phospholipids in phagocytosis 105298 NA True False NA 105501 NA True False Acyl chain remodelling of PE 107569 NA True False Pyrimidine catabolism 107589 NA True False Smooth Muscle Contraction;RHO GTPases activate PAKs 107686 NA True False snRNP Assembly;mRNA Splicing - Major Pathway;mRNA Splicing - Minor Pathway 109815 NA True False NA 110052 NA True False B-WICH complex positively regulates rRNA expression;Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 112417 NA True False Glucuronidation 114774 Pawr True True NA 126133 NA False True NA 128866 NA False True NA 129563 NA False True NA 146956 NA False True NA 148423 NA False True NA 151903 NA False True NA 162073 NA False True NA 170791 Rbm39 False True NA 192159 Prpf8 True True mRNA Splicing - Major Pathway;mRNA Splicing - Minor Pathway 200933 NA False True NA 201595 NA False True NA 203068 NA False True NA 211666 NA True False Glutathione conjugation 216350 NA True False NA 217069 Trim25 True True ISG15 antiviral mechanism;Termination of translesion DNA synthesis 217845 NA True False NA 218397 Rasa1 False True Downstream signal transduction;EPHB-mediated forward signaling;VEGFR2 mediated cell proliferation;Regulation of RAS by GAPs;PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 219158 NA True False Regulation of HSF1-mediated heat shock response 223672 NA True False Scavenging of heme from plasma;Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs);Post-translational protein phosphorylation 224045 NA True False Recycling of eIF2:GDP 225027 NA True False Cleavage of Growing Transcript in the Termination Region ;Transport of Mature mRNA derived from an Intron-Containing Transcript;mRNA Splicing - Major Pathway;mRNA Splicing - Minor Pathway;mRNA 3'-end processing 225884 NA True False NA 226101 NA True False NA 226654 NA True False Sulfide oxidation to sulfate 227620 NA True False NA 228869 NA False True NA 229279 Hnrnpa3 True True mRNA Splicing - Major Pathway 229615 NA False True SUMOylation of transcription factors;SUMOylation of transcription cofactors;SUMOylation of intracellular receptors;Formation of Incision Complex in GG-NER 230073 Ddx58 False True ISG15 antiviral mechanism;Ub-specific processing proteases;OAS antiviral response;Negative regulators of DDX58/IFIH1 signaling 230257 NA True False NA 230753 NA True False NA 230908 Tardbp True True NA 231655 NA True False OAS antiviral response 234663 NA True False Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal;MHC class II antigen presentation;Separation of Sister Chromatids;Resolution of Sister Chromatid Cohesion;HSP90 chaperone cycle for steroid hormone receptors (SHR);RHO GTPases Activate Formins;COPI-mediated anterograde transport;COPI-independent Golgi-to-ER retrograde traffic;Mitotic Prometaphase 236539 NA True False Serine biosynthesis 239017 NA True False NA 239217 NA True False NA 242291 NA True False Cytosolic sulfonation of small molecules 246184 NA False True NA 246730 Oas1a True True NA 253260 NA False True NA 253635 NA False True NA 269774 NA True False Cargo recognition for clathrin-mediated endocytosis;Clathrin-mediated endocytosis 283459 NA False True NA 284695 NA False True NA 331401 NA True False Cleavage of Growing Transcript in the Termination Region ;Transport of Mature mRNA derived from an Intron-Containing Transcript;mRNA 3'-end processing 331487 NA True False NA 374786 NA False True NA 378435 Mafa False True NA 384009 NA True False NA 389677 NA False True NA 440145 NA False True NA 445007 NA True False Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal;Transport of Mature mRNA derived from an Intron-Containing Transcript;Separation of Sister Chromatids;Resolution of Sister Chromatid Cohesion;SUMOylation of DNA damage response and repair proteins;Nuclear Pore Complex (NPC) Disassembly;Regulation of HSF1-mediated heat shock response;SUMOylation of DNA replication proteins;RHO GTPases Activate Formins;Mitotic Prometaphase 646960 NA False True NA 653784 NA False True NA 855411 NA False True NA 100038882 Isg15 True True ISG15 antiviral mechanism;Termination of translesion DNA synthesis 100042295 NA True False Glutathione conjugation 100287932 NA False True NA NA NA True False NA