# HG changeset patch # User proteore # Date 1519916718 18000 # Node ID bd052861852bb51f56bd8bac2c517a34e4174393 planemo upload commit ffa3be72b850aecbfbd636de815967c06a8f643f-dirty diff -r 000000000000 -r bd052861852b GO-enrich.R --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/GO-enrich.R Thu Mar 01 10:05:18 2018 -0500 @@ -0,0 +1,167 @@ +library(clusterProfiler) + +#library(org.Sc.sgd.db) +library(org.Hs.eg.db) +library(org.Mm.eg.db) + +# Read file and return file content as data.frame? +readfile = function(filename, header) { + if (header == "true") { + # Read only the first line of the files as data (without headers): + headers <- read.table(filename, nrows = 1, header = FALSE, sep = "\t", stringsAsFactors = FALSE, fill = TRUE, na.strings=c("", "NA"), blank.lines.skip = TRUE) + #Read the data of the files (skipping the first row): + file <- read.table(filename, skip = 1, header = FALSE, sep = "\t", stringsAsFactors = FALSE, fill = TRUE, na.strings=c("", "NA"), blank.lines.skip = TRUE) + # Remove empty rows + file <- file[!apply(is.na(file) | file == "", 1, all), , drop=FALSE] + #And assign the headers of step two to the data: + names(file) <- headers + } + else { + file <- read.table(filename, header = FALSE, sep = "\t", stringsAsFactors = FALSE, fill = TRUE, na.strings=c("", "NA"), blank.lines.skip = TRUE) + file <- file[!apply(is.na(file) | file == "", 1, all), , drop=FALSE] + } + return(file) +} + +repartition.GO <- function(geneid, orgdb, ontology, level=3, readable=TRUE) { + ggo<-groupGO(gene=geneid, + OrgDb = orgdb, + ont=ontology, + level=level, + readable=TRUE) + name <- paste("GGO.", ontology, ".png", sep = "") + png(name) + p <- barplot(ggo) + print(p) + dev.off() + return(ggo) +} + +# GO over-representation test +enrich.GO <- function(geneid, orgdb, ontology, pval_cutoff, qval_cutoff) { + ego<-enrichGO(gene=geneid, + OrgDb=orgdb, + keytype="ENTREZID", + ont=ontology, + pAdjustMethod="BH", + pvalueCutoff=pval_cutoff, + qvalueCutoff=qval_cutoff, + readable=TRUE) + bar_name <- paste("EGO.", ontology, ".bar.png", sep = "") + png(bar_name) + p <- barplot(ego) + print(p) + dev.off() + dot_name <- paste("EGO.", ontology, ".dot.png", sep = "") + png(dot_name) + p <- dotplot(ego) + print(p) + dev.off() + return(ego) +} + +clusterProfiler = function() { + args <- commandArgs(TRUE) + if(length(args)<1) { + args <- c("--help") + } + + # Help section + if("--help" %in% args) { + cat("clusterProfiler Enrichment Analysis + Arguments: + --input_type: type of input (list of id or filename) + --input: input + --ncol: the column number which you would like to apply... + --header: true/false if your file contains a header + --id_type: the type of input IDs (UniProt/EntrezID) + --species + --onto_opt: ontology options + --go_function: groupGO/enrichGO + --level: 1-3 + --pval_cutoff + --qval_cutoff + --text_output: text output filename \n") + q(save="no") + } + # Parse arguments + parseArgs <- function(x) strsplit(sub("^--", "", x), "=") + argsDF <- as.data.frame(do.call("rbind", parseArgs(args))) + args <- as.list(as.character(argsDF$V2)) + names(args) <- argsDF$V1 + + input_type = args$input_type + if (input_type == "text") { + input = args$input + } + else if (input_type == "file") { + filename = args$input + ncol = args$ncol + # Check ncol + if (! as.numeric(gsub("c", "", ncol)) %% 1 == 0) { + stop("Please enter an integer for level") + } + else { + ncol = as.numeric(gsub("c", "", ncol)) + } + header = args$header + # Get file content + file = readfile(filename, header) + # Extract Protein IDs list + input = c() + for (row in as.character(file[,ncol])) { + input = c(input, strsplit(row, ";")[[1]][1]) + } + } + id_type = args$id_type + + + #ID format Conversion + #This case : from UNIPROT (protein id) to ENTREZ (gene id) + #bitr = conversion function from clusterProfiler + + if (args$species=="human") { + orgdb<-org.Hs.eg.db + } + else if (args$species=="mouse") { + orgdb<-org.Mm.eg.db + } + else if (args$species=="rat") { + orgdb<-org.Rn.eg.db + } + + ##to initialize + if (id_type=="Uniprot") { + idFrom<-"UNIPROT" + idTo<-"ENTREZID" + gene<-bitr(input, fromType=idFrom, toType=idTo, OrgDb=orgdb) + } + else if (id_type=="Entrez") { + gene<-input + } + + ontology <- strsplit(args$onto_opt, ",")[[1]] + if (args$go_represent == "true") { + go_represent <- args$go_represent + level <- as.numeric(args$level) + } + if (args$go_enrich == "true") { + go_enrich <- args$go_enrich + pval_cutoff <- as.numeric(args$pval_cutoff) + qval_cutoff <- as.numeric(args$qval_cutoff) + } + + ##enrichGO : GO over-representation test + for (onto in ontology) { + if (args$go_represent == "true") { + ggo<-repartition.GO(gene$ENTREZID, orgdb, onto, level, readable=TRUE) + write.table(ggo, args$text_output, append = TRUE, sep="\t", row.names = FALSE, quote=FALSE) + } + if (args$go_enrich == "true") { + ego<-enrich.GO(gene$ENTREZID, orgdb, onto, pval_cutoff, qval_cutoff) + write.table(ego, args$text_output, append = TRUE, sep="\t", row.names = FALSE, quote=FALSE) + } + } +} + +clusterProfiler() diff -r 000000000000 -r bd052861852b README.rst --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/README.rst Thu Mar 01 10:05:18 2018 -0500 @@ -0,0 +1,45 @@ +Wrapper for clusterProfiler Enrichment Analysis Tool +==================================================== + +**Authors** + +clusterProfiler R package reference : +G Yu, LG Wang, Y Han, QY He. clusterProfiler: an R package for comparing biological themes among gene clusters. +OMICS: A Journal of Integrative Biology 2012, 16(5):284-287. +doi:[10.1089/omi.2011.0118](http://dx.doi.org/10.1089/omi.2011.0118) + + +**Galaxy integration** + +T.P. Lien Nguyen, Florence Combes, Yves Vandenbrouck CEA, INSERM, CNRS, Grenoble-Alpes University, BIG Institute, FR + +Sandra Dérozier, Olivier Rué, Christophe Caron, Valentin Loux INRA, Paris-Saclay University, MAIAGE Unit, Migale Bioinformatics platform + +This work has been partially funded through the French National Agency for Research (ANR) IFB project. + +Contact support@proteore.org for any questions or concerns about the Galaxy implementation of this tool. + + +=================== + +**Galaxy component based on R package clusterProfiler (see ref below)** + +This component allows to perform GO enrichment-analyses. +Given a list of IDs, the tool either +(i) performs gene classification based on GO distribution at a specific level, or +(ii) calculates GO categories enrichment (over- or under-representation) for the IDs of the input list, +compared to a background (whole organism or user-defined list). + +**Input required** + +This component works with Gene ids (e.g : 4151, 7412) or Uniprot accession number (e.g. P31946). +You can copy/paste these identifiers or supply a tabular file (.csv, .tsv, .txt, .tab) where there are contained. + + +**Output** + +Text (tables) and graphics representing the repartition and/or enrichment of GO categories. + +**User manual / Documentation** of the clusterProfiler R package (functions and parameters): +https://bioconductor.org/packages/3.7/bioc/vignettes/clusterProfiler/inst/doc/clusterProfiler.html +(Very well explained) \ No newline at end of file diff -r 000000000000 -r bd052861852b cluster_profiler.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/cluster_profiler.xml Thu Mar 01 10:05:18 2018 -0500 @@ -0,0 +1,205 @@ + + + R + bioconductor-org.hs.eg.db + bioconductor-org.mm.eg.db + bioconductor-dose + bioconductor-clusterprofiler + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff -r 000000000000 -r bd052861852b test-data/Lacombe_et_al_2017_OK.txt --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/Lacombe_et_al_2017_OK.txt Thu Mar 01 10:05:18 2018 -0500 @@ -0,0 +1,165 @@ +Protein accession number (UniProt) Protein name Number of peptides (razor + unique) +P15924 Desmoplakin 69 +P02538 Keratin, type II cytoskeletal 6A 53 +P02768 Serum albumin 44 +P08779 Keratin, type I cytoskeletal 16 29 +Q02413 Desmoglein-1 24 +P07355 "Annexin A2;Putative annexin A2-like protein" 22 +P14923 Junction plakoglobin 22 +P02788 Lactotransferrin 21 +Q9HC84 Mucin-5B 21 +P29508 Serpin B3 20 +P63261 Actin, cytoplasmic 2 19 +Q8N1N4 Keratin, type II cytoskeletal 78 18 +Q04695 Keratin, type I cytoskeletal 17 18 +P01876 Ig alpha-1 chain C region 16 +Q01469 Fatty acid-binding protein 5, epidermal 15 +P31944 Caspase-14 15 +P01833 Polymeric immunoglobulin receptor 15 +P06733 Alpha-enolase 15 +P25311 Zinc-alpha-2-glycoprotein 15 +Q15149 Plectin 15 +P19013 Keratin, type II cytoskeletal 4 13 +Q6KB66 Keratin, type II cytoskeletal 80 13 +Q08188 Protein-glutamine gamma-glutamyltransferase E 12 +P13646 Keratin, type I cytoskeletal 13 11 +Q86YZ3 Hornerin 11 +P04259 Keratin, type II cytoskeletal 6B 10 +P02545 "Prelamin-A/C;Lamin-A/C" 10 +P04083 Annexin A1 10 +P11021 78 kDa glucose-regulated protein 10 +P02787 Serotransferrin 9 +P04040 Catalase 9 +P31151 Protein S100-A7 9 +P31947 14-3-3 protein sigma 9 +Q96P63 Serpin B12 9 +P14618 Pyruvate kinase PKM 9 +P60174 Triosephosphate isomerase 9 +Q06830 Peroxiredoxin-1 9 +P01040 Cystatin-A 8 +P05089 Arginase-1 8 +P01834 Ig kappa chain C region 8 +P04406 Glyceraldehyde-3-phosphate dehydrogenase 8 +P0DMV9 Heat shock 70 kDa protein 1B 8 +P13639 Elongation factor 2 8 +P35579 Myosin-9 8 +P68371 Tubulin beta-4B chain 8 +Q8WVV4 Protein POF1B 8 +O75635 Serpin B7 7 +P01857 Ig gamma-1 chain C region 7 +P61626 Lysozyme C 7 +P68363 Tubulin alpha-1B chain 7 +P01009 "Alpha-1-antitrypsin;Short peptide from AAT" 6 +P07900 Heat shock protein HSP 90-alpha 6 +Q9NZH8 Interleukin-36 gamma 6 +O43707 "Alpha-actinin-4;Alpha-actinin-1" 6 +O75223 Gamma-glutamylcyclotransferase 6 +P00338 L-lactate dehydrogenase A chain 6 +P07339 Cathepsin D 6 +P62987 Ubiquitin-60S ribosomal protein L40 6 +P10599 Thioredoxin 6 +Q9UGM3 Deleted in malignant brain tumors 1 protein 6 +Q9UI42 Carboxypeptidase A4 6 +P47929 Galectin-7 5 +Q13867 Bleomycin hydrolase 5 +Q6P4A8 Phospholipase B-like 1 5 +O75369 Filamin-B 5 +P00441 Superoxide dismutase [Cu-Zn] 5 +P04792 Heat shock protein beta-1 5 +P11142 Heat shock cognate 71 kDa protein 5 +P58107 Epiplakin 5 +P60842 Eukaryotic initiation factor 4A-I 5 +P62937 Peptidyl-prolyl cis-trans isomerase A 5 +P63104 14-3-3 protein zeta/delta 5 +Q92820 Gamma-glutamyl hydrolase 5 +O75342 Arachidonate 12-lipoxygenase, 12R-type 4 +P09211 Glutathione S-transferase P 4 +P31025 Lipocalin-1 4 +P48594 Serpin B4 4 +Q14574 Desmocollin-3 4 +Q5T750 Skin-specific protein 32 4 +Q6UWP8 Suprabasin 4 +O60911 Cathepsin L2 4 +P00558 Phosphoglycerate kinase 1 4 +P04075 Fructose-bisphosphate aldolase A 4 +P07384 Calpain-1 catalytic subunit 4 +P0CG05 Ig lambda-2 chain C regions 4 +P18206 Vinculin 4 +P62258 14-3-3 protein epsilon 4 +P68871 Hemoglobin subunit beta 4 +Q9C075 Keratin, type I cytoskeletal 23 4 +A8K2U0 Alpha-2-macroglobulin-like protein 1 3 +P00738 Haptoglobin 3 +P01011 Alpha-1-antichymotrypsin 3 +P02763 Alpha-1-acid glycoprotein 1 3 +P18510 Interleukin-1 receptor antagonist protein 3 +P22528 Cornifin-B 3 +P30740 Leukocyte elastase inhibitor 3 +P80188 Neutrophil gelatinase-associated lipocalin 3 +Q15828 Cystatin-M 3 +Q9HCY8 Protein S100-A14 3 +P01623 Ig kappa chain V-III region 3 +P01877 Ig alpha-2 chain C region 3 +P06396 Gelsolin 3 +P14735 Insulin-degrading enzyme 3 +P20933 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase 3 +P25788 Proteasome subunit alpha type-3 3 +P26641 Elongation factor 1-gamma 3 +P36952 Serpin B5 3 +P40926 Malate dehydrogenase, mitochondrial 3 +Q9Y6R7 IgGFc-binding protein 3 +O95274 Ly6/PLAUR domain-containing protein 3 2 +P00491 Purine nucleoside phosphorylase 2 +P04080 Cystatin-B 2 +P09972 Fructose-bisphosphate aldolase C 2 +P19012 Keratin, type I cytoskeletal 15 2 +P20930 Filaggrin 2 +Q96FX8 p53 apoptosis effector related to PMP-22 2 +Q9UIV8 Serpin B13 2 +P01625 Ig kappa chain V-IV region Len 2 +P01765 Ig heavy chain V-III region TIL 2 +P01766 Ig heavy chain V-III region BRO 2 +P01860 Ig gamma-3 chain C region 2 +P01871 Ig mu chain C region 2 +P05090 Apolipoprotein D 2 +P06870 Kallikrein-1 2 +P07858 Cathepsin B 2 +P08865 40S ribosomal protein SA 2 +P11279 Lysosome-associated membrane glycoprotein 1 2 +P13473 Lysosome-associated membrane glycoprotein 2 2 +P19971 Thymidine phosphorylase 2 +P23284 Peptidyl-prolyl cis-trans isomerase B 2 +P23396 40S ribosomal protein S3 2 +P25705 ATP synthase subunit alpha, mitochondrial 2 +P27482 Calmodulin-like protein 3 2 +P31949 Protein S100-A11 2 +P40121 Macrophage-capping protein 2 +P42357 Histidine ammonia-lyase 2 +P47756 F-actin-capping protein subunit beta 2 +P48637 Glutathione synthetase 2 +P49720 Proteasome subunit beta type-3 2 +P50395 Rab GDP dissociation inhibitor beta 2 +P59998 Actin-related protein 2/3 complex subunit 4 2 +P61160 Actin-related protein 2 2 +P61916 Epididymal secretory protein E1 2 +P04745 Alpha-amylase 1 23 +Q9NZT1 Calmodulin-like protein 5 8 +P12273 Prolactin-inducible protein 6 +Q96DA0 Zymogen granule protein 16 homolog B 5 +P01036 Cystatin-S 5 +Q8TAX7 Mucin-7 2 +P01037 Cystatin-SN 2 +P09228 Cystatin-SA 2 +P04264 Keratin, type II cytoskeletal 1 61 +P35908 Keratin, type II cytoskeletal 2 epidermal 40 +P13645 Keratin, type I cytoskeletal 10 40 +Q5D862 Filaggrin-2 14 +Q5T749 Keratinocyte proline-rich protein 13 +Q8IW75 Serpin A12 3 +P81605 Dermcidin 3 +P22531 Small proline-rich protein 2E 3 +P59666 Neutrophil defensin 3 2 +P78386 Keratin, type II cuticular Hb5 2 + + + diff -r 000000000000 -r bd052861852b test-data/clusterProfiler_diagram_outputs__GGO.CC.png Binary file test-data/clusterProfiler_diagram_outputs__GGO.CC.png has changed diff -r 000000000000 -r bd052861852b test-data/clusterProfiler_text_output.tabular --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/clusterProfiler_text_output.tabular Thu Mar 01 10:05:18 2018 -0500 @@ -0,0 +1,378 @@ +ID Description Count GeneRatio geneID +GO:0005886 plasma membrane 56 56/153 DSP/DSG1/ANXA2/JUP/MUC5B/ACTG1/FABP5/PIGR/ENO1/AZGP1/PLEC/TGM3/HRNR/ANXA1/HSPA5/TF/CAT/SERPINB12/CSTA/GAPDH/EEF2/MYH9/HSP90AA1/UBA52/FLNB/SOD1/HSPB1/HSPA8/EPPK1/GSTP1/DSC3/C1orf68/CTSV/CAPN1/VCL/YWHAE/IL1RN/SPRR1B/CST6/GSN/IDE/LYPD3/FLG/PERP/RPSA/LAMP1/LAMP2/RPS3/ATP5A1/PIP/MUC7/KRT1/KRT2/KRT10/SERPINA12/SPRR2E +GO:0005628 prospore membrane 0 0/153 +GO:0005789 endoplasmic reticulum membrane 1 1/153 HSPA5 +GO:0019867 outer membrane 2 2/153 ARG1/UBA52 +GO:0031090 organelle membrane 24 24/153 DSP/DSG1/ANXA2/FABP5/PIGR/LMNA/ANXA1/TF/CAT/SFN/SERPINB12/ARG1/GAPDH/SERPINA1/UBA52/DMBT1/HSPA8/YWHAZ/YWHAE/MDH2/LAMP1/LAMP2/RPS3/ATP5A1 +GO:0034357 photosynthetic membrane 0 0/153 +GO:0036362 ascus membrane 0 0/153 +GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 1 1/153 HSPA5 +GO:0044425 membrane part 28 28/153 DSP/DSG1/ANXA2/JUP/PIGR/TGM3/ANXA1/HSPA5/TF/EEF2/MYH9/TUBA1B/HSP90AA1/CTSD/DMBT1/FLNB/HSPA8/EPPK1/DSC3/CTSV/PGK1/LYPD3/PERP/LAMP1/LAMP2/RPS3/ATP5A1/PIP +GO:0048475 coated membrane 0 0/153 +GO:0055036 virion membrane 0 0/153 +GO:0098552 side of membrane 8 8/153 DSG1/JUP/TGM3/ANXA1/TF/HSPA8/CTSV/LAMP1 +GO:0098589 membrane region 7 7/153 ANXA2/TF/EEF2/TUBA1B/CTSD/PGK1/LAMP2 +GO:0098590 plasma membrane region 10 10/153 DSP/DSG1/ANXA2/JUP/ANXA1/TF/HSP90AA1/EPPK1/RPS3/PIP +GO:0098796 membrane protein complex 3 3/153 JUP/MYH9/ATP5A1 +GO:0098805 whole membrane 19 19/153 DSP/DSG1/ANXA2/FABP5/PIGR/ANXA1/TF/CAT/SERPINB12/ARG1/EEF2/TUBA1B/CTSD/UBA52/DMBT1/HSPA8/PGK1/LAMP1/LAMP2 +GO:1990195 macrolide transmembrane transporter complex 0 0/153 +GO:1990196 MacAB-TolC complex 0 0/153 +GO:1990578 perinuclear endoplasmic reticulum membrane 0 0/153 +GO:1990850 H-gal-GP complex 0 0/153 +GO:0010367 extracellular isoamylase complex 0 0/153 +GO:0031012 extracellular matrix 28 28/153 DSP/DSG1/ANXA2/JUP/ACTG1/CASP14/PLEC/LMNA/HSPA5/PKM/PRDX1/CSTA/GAPDH/EEF2/MYH9/TUBB4B/SERPINA1/CTSD/FLNB/SOD1/HSPB1/HSPA8/EIF4A1/SBSN/RPS3/ATP5A1/KRT1/DCD +GO:0043083 synaptic cleft 0 0/153 +GO:0043230 extracellular organelle 130 130/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/ENO1/AZGP1/PLEC/TGM3/KRT13/HRNR/KRT6B/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/TPI1/PRDX1/CSTA/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/LYZ/TUBA1B/SERPINA1/HSP90AA1/ACTN4/GGCT/LDHA/CTSD/UBA52/TXN/DMBT1/LGALS7B/BLMH/FLNB/SOD1/HSPB1/HSPA8/EIF4A1/PPIA/YWHAZ/GGH/GSTP1/LCN1/SERPINB4/C1orf68/SBSN/CTSV/PGK1/ALDOA/CAPN1/VCL/YWHAE/HBB/A2ML1/HP/SERPINA3/ORM1/IL1RN/SPRR1B/SERPINB1/LCN2/CST6/S100A14/GSN/AGA/PSMA3/EEF1G/SERPINB5/MDH2/FCGBP/PNP/CSTB/ALDOC/KRT15/SERPINB13/APOD/KLK1/CTSB/RPSA/LAMP1/LAMP2/PPIB/RPS3/ATP5A1/CALML3/S100A11/CAPG/CAPZB/GSS/PSMB3/GDI2/ARPC4/ACTR2/NPC2/AMY1A/AMY1B/AMY1C/CALML5/PIP/ZG16B/CST4/MUC7/KRT1/KRT2/KRT10/FLG2/KPRP/DCD/DEFA3 +GO:0044421 extracellular region part 141 141/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/ENO1/AZGP1/PLEC/TGM3/KRT13/HRNR/KRT6B/LMNA/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/TPI1/PRDX1/CSTA/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/SERPINB7/LYZ/TUBA1B/SERPINA1/HSP90AA1/IL36G/ACTN4/GGCT/LDHA/CTSD/UBA52/TXN/DMBT1/CPA4/LGALS7B/BLMH/PLBD1/FLNB/SOD1/HSPB1/HSPA8/EIF4A1/PPIA/YWHAZ/GGH/GSTP1/LCN1/SERPINB4/C1orf68/SBSN/CTSV/PGK1/ALDOA/CAPN1/VCL/YWHAE/HBB/A2ML1/HP/SERPINA3/ORM1/IL1RN/SPRR1B/SERPINB1/LCN2/CST6/S100A14/GSN/IDE/AGA/PSMA3/EEF1G/SERPINB5/MDH2/FCGBP/LYPD3/PNP/CSTB/ALDOC/KRT15/SERPINB13/APOD/KLK1/CTSB/RPSA/LAMP1/LAMP2/PPIB/RPS3/ATP5A1/CALML3/S100A11/CAPG/CAPZB/GSS/PSMB3/GDI2/ARPC4/ACTR2/NPC2/AMY1A/AMY1B/AMY1C/CALML5/PIP/ZG16B/CST4/MUC7/CST1/CST2/KRT1/KRT2/KRT10/FLG2/KPRP/SERPINA12/DCD/DEFA3/KRT85 +GO:0048046 apoplast 0 0/153 +GO:0070062 extracellular exosome 130 130/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/ENO1/AZGP1/PLEC/TGM3/KRT13/HRNR/KRT6B/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/TPI1/PRDX1/CSTA/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/LYZ/TUBA1B/SERPINA1/HSP90AA1/ACTN4/GGCT/LDHA/CTSD/UBA52/TXN/DMBT1/LGALS7B/BLMH/FLNB/SOD1/HSPB1/HSPA8/EIF4A1/PPIA/YWHAZ/GGH/GSTP1/LCN1/SERPINB4/C1orf68/SBSN/CTSV/PGK1/ALDOA/CAPN1/VCL/YWHAE/HBB/A2ML1/HP/SERPINA3/ORM1/IL1RN/SPRR1B/SERPINB1/LCN2/CST6/S100A14/GSN/AGA/PSMA3/EEF1G/SERPINB5/MDH2/FCGBP/PNP/CSTB/ALDOC/KRT15/SERPINB13/APOD/KLK1/CTSB/RPSA/LAMP1/LAMP2/PPIB/RPS3/ATP5A1/CALML3/S100A11/CAPG/CAPZB/GSS/PSMB3/GDI2/ARPC4/ACTR2/NPC2/AMY1A/AMY1B/AMY1C/CALML5/PIP/ZG16B/CST4/MUC7/KRT1/KRT2/KRT10/FLG2/KPRP/DCD/DEFA3 +GO:0098595 perivitelline space 0 0/153 +GO:0099544 perisynaptic space 0 0/153 +GO:1903561 extracellular vesicle 130 130/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/ENO1/AZGP1/PLEC/TGM3/KRT13/HRNR/KRT6B/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/TPI1/PRDX1/CSTA/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/LYZ/TUBA1B/SERPINA1/HSP90AA1/ACTN4/GGCT/LDHA/CTSD/UBA52/TXN/DMBT1/LGALS7B/BLMH/FLNB/SOD1/HSPB1/HSPA8/EIF4A1/PPIA/YWHAZ/GGH/GSTP1/LCN1/SERPINB4/C1orf68/SBSN/CTSV/PGK1/ALDOA/CAPN1/VCL/YWHAE/HBB/A2ML1/HP/SERPINA3/ORM1/IL1RN/SPRR1B/SERPINB1/LCN2/CST6/S100A14/GSN/AGA/PSMA3/EEF1G/SERPINB5/MDH2/FCGBP/PNP/CSTB/ALDOC/KRT15/SERPINB13/APOD/KLK1/CTSB/RPSA/LAMP1/LAMP2/PPIB/RPS3/ATP5A1/CALML3/S100A11/CAPG/CAPZB/GSS/PSMB3/GDI2/ARPC4/ACTR2/NPC2/AMY1A/AMY1B/AMY1C/CALML5/PIP/ZG16B/CST4/MUC7/KRT1/KRT2/KRT10/FLG2/KPRP/DCD/DEFA3 +GO:0044464 cell part 136 136/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/ENO1/AZGP1/PLEC/KRT80/TGM3/KRT13/HRNR/KRT6B/LMNA/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/TPI1/PRDX1/CSTA/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/SERPINB7/LYZ/TUBA1B/SERPINA1/HSP90AA1/ACTN4/GGCT/LDHA/CTSD/UBA52/TXN/DMBT1/LGALS7B/BLMH/PLBD1/FLNB/SOD1/HSPB1/HSPA8/EPPK1/EIF4A1/PPIA/YWHAZ/GGH/ALOX12B/GSTP1/SERPINB4/DSC3/C1orf68/CTSV/PGK1/ALDOA/CAPN1/VCL/YWHAE/HBB/KRT23/HP/SERPINA3/ORM1/IL1RN/SPRR1B/SERPINB1/LCN2/CST6/S100A14/GSN/IDE/AGA/PSMA3/EEF1G/SERPINB5/MDH2/LYPD3/PNP/CSTB/ALDOC/KRT15/FLG/PERP/SERPINB13/APOD/KLK1/CTSB/RPSA/LAMP1/LAMP2/TYMP/PPIB/RPS3/ATP5A1/S100A11/CAPG/HAL/CAPZB/GSS/PSMB3/GDI2/ARPC4/ACTR2/NPC2/CALML5/PIP/MUC7/KRT1/KRT2/KRT10/FLG2/KPRP/SERPINA12/SPRR2E/DEFA3/KRT85 +GO:1990065 Dxr protein complex 0 0/153 +GO:1990204 oxidoreductase complex 0 0/153 +GO:1990455 PTEN phosphatase complex 0 0/153 +GO:1990722 DAPK1-calmodulin complex 0 0/153 +GO:0039642 virion nucleoid 0 0/153 +GO:0042645 mitochondrial nucleoid 0 0/153 +GO:0042646 plastid nucleoid 0 0/153 +GO:0043590 bacterial nucleoid 0 0/153 +GO:0044777 single-stranded DNA-binding protein complex 0 0/153 +GO:0044423 virion part 0 0/153 +GO:0005911 cell-cell junction 13 13/153 DSP/DSG1/ANXA2/JUP/ANXA1/MYH9/POF1B/ACTN4/EPPK1/DSC3/VCL/PERP/S100A11 +GO:0030055 cell-substrate junction 25 25/153 JUP/ACTG1/PLEC/ANXA1/HSPA5/CAT/S100A7/HSPA1A/HSPA1B/MYH9/ACTN4/FLNB/HSPB1/HSPA8/EPPK1/PPIA/YWHAZ/CAPN1/VCL/YWHAE/GSN/PPIB/RPS3/GDI2/ACTR2 +GO:0061466 plasma membrane part of cell junction 0 0/153 +GO:0070161 anchoring junction 31 31/153 DSP/DSG1/ANXA2/JUP/ACTG1/PLEC/ANXA1/HSPA5/CAT/S100A7/HSPA1A/HSPA1B/MYH9/POF1B/ACTN4/FLNB/HSPB1/HSPA8/PPIA/YWHAZ/DSC3/CAPN1/VCL/YWHAE/GSN/PERP/PPIB/RPS3/S100A11/GDI2/ACTR2 +GO:0043233 organelle lumen 70 70/153 ALB/ANXA2/JUP/LTF/MUC5B/SERPINB3/FABP5/HRNR/LMNA/ANXA1/HSPA5/TF/CAT/S100A7/PKM/ARG1/HSPA1A/HSPA1B/EEF2/TUBB4B/LYZ/SERPINA1/HSP90AA1/ACTN4/CTSD/UBA52/SOD1/HSPA8/EPPK1/PPIA/YWHAZ/GGH/GSTP1/CTSV/ALDOA/CAPN1/VCL/HBB/HP/SERPINA3/ORM1/SERPINB1/LCN2/S100A14/GSN/IDE/AGA/PSMA3/MDH2/PNP/CSTB/ALDOC/SERPINB13/CTSB/RPSA/LAMP2/PPIB/RPS3/ATP5A1/S100A11/CAPG/PSMB3/GDI2/ACTR2/NPC2/CALML5/MUC7/KRT1/FLG2/DEFA3 +GO:0001114 protein-DNA-RNA complex 0 0/153 +GO:0005952 cAMP-dependent protein kinase complex 0 0/153 +GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex 0 0/153 +GO:0017053 transcriptional repressor complex 0 0/153 +GO:0032992 protein-carbohydrate complex 0 0/153 +GO:0032993 protein-DNA complex 1 1/153 JUP +GO:0032994 protein-lipid complex 0 0/153 +GO:0034518 RNA cap binding complex 0 0/153 +GO:0035003 subapical complex 0 0/153 +GO:0036125 fatty acid beta-oxidation multienzyme complex 0 0/153 +GO:0043234 protein complex 30 30/153 ALB/ANXA2/JUP/LTF/ACTG1/ANXA1/HSPA5/GAPDH/MYH9/ACTN4/SOD1/HSPB1/HSPA8/EIF4A1/GSTP1/VCL/YWHAE/HBB/HP/GSN/IDE/PSMA3/PPIB/RPS3/ATP5A1/CAPG/CAPZB/PSMB3/ARPC4/ACTR2 +GO:0043235 receptor complex 3 3/153 PIGR/TF/MYH9 +GO:0044815 DNA packaging complex 0 0/153 +GO:0046536 dosage compensation complex 0 0/153 +GO:0061742 chaperone-mediated autophagy translocation complex 0 0/153 +GO:0061838 CENP-T-W-S-X complex 0 0/153 +GO:0070864 sperm individualization complex 0 0/153 +GO:0098636 protein complex involved in cell adhesion 1 1/153 MYH9 +GO:0098774 curli 0 0/153 +GO:0099023 tethering complex 0 0/153 +GO:0140007 KICSTOR complex 0 0/153 +GO:1902494 catalytic complex 8 8/153 ENO1/HSPA1A/HSPA1B/HSPB1/HSPA8/IDE/PSMA3/PSMB3 +GO:1902695 metallochaperone complex 0 0/153 +GO:1902773 GTPase activator complex 0 0/153 +GO:1903269 ornithine carbamoyltransferase inhibitor complex 0 0/153 +GO:1903502 translation repressor complex 0 0/153 +GO:1903503 ATPase inhibitor complex 0 0/153 +GO:1903865 sigma factor antagonist complex 0 0/153 +GO:1904090 peptidase inhibitor complex 0 0/153 +GO:1990104 DNA bending complex 0 0/153 +GO:1990229 iron-sulfur cluster assembly complex 0 0/153 +GO:1990249 nucleotide-excision repair, DNA damage recognition complex 0 0/153 +GO:1990351 transporter complex 0 0/153 +GO:1990391 DNA repair complex 0 0/153 +GO:1990415 Pex17p-Pex14p docking complex 0 0/153 +GO:1990684 protein-lipid-RNA complex 0 0/153 +GO:1990862 nuclear membrane complex Bqt3-Bqt4 0 0/153 +GO:1990904 ribonucleoprotein complex 10 10/153 GAPDH/HSPA1A/HSPA1B/EEF2/ACTN4/UBA52/HSPA8/APOD/RPSA/RPS3 +GO:1990923 PET complex 0 0/153 +GO:0000313 organellar ribosome 0 0/153 +GO:0005929 cilium 2 2/153 ANXA1/PKM +GO:0043227 membrane-bounded organelle 136 136/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/ENO1/AZGP1/PLEC/TGM3/KRT13/HRNR/KRT6B/LMNA/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/TPI1/PRDX1/CSTA/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/LYZ/TUBA1B/SERPINA1/HSP90AA1/ACTN4/GGCT/LDHA/CTSD/UBA52/TXN/DMBT1/LGALS7B/BLMH/PLBD1/FLNB/SOD1/HSPB1/HSPA8/EPPK1/EIF4A1/PPIA/YWHAZ/GGH/GSTP1/LCN1/SERPINB4/C1orf68/SBSN/CTSV/PGK1/ALDOA/CAPN1/VCL/YWHAE/HBB/A2ML1/HP/SERPINA3/ORM1/IL1RN/SPRR1B/SERPINB1/LCN2/CST6/S100A14/GSN/IDE/AGA/PSMA3/EEF1G/SERPINB5/MDH2/FCGBP/PNP/CSTB/ALDOC/KRT15/FLG/PERP/SERPINB13/APOD/KLK1/CTSB/RPSA/LAMP1/LAMP2/PPIB/RPS3/ATP5A1/CALML3/S100A11/CAPG/CAPZB/GSS/PSMB3/GDI2/ARPC4/ACTR2/NPC2/AMY1A/AMY1B/AMY1C/CALML5/PIP/ZG16B/CST4/MUC7/KRT1/KRT2/KRT10/FLG2/KPRP/DCD/DEFA3 +GO:0043228 non-membrane-bounded organelle 51 51/153 DSP/KRT6A/KRT16/ANXA2/JUP/ACTG1/KRT78/KRT17/CASP14/ENO1/PLEC/KRT80/KRT13/KRT6B/LMNA/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/TUBA1B/ACTN4/UBA52/FLNB/HSPB1/HSPA8/EPPK1/CTSV/ALDOA/VCL/YWHAE/KRT23/GSN/PNP/CSTB/ALDOC/KRT15/FLG/APOD/CTSB/RPSA/RPS3/CAPG/CAPZB/ARPC4/ACTR2/KRT1/KRT2/KRT10/KRT85 +GO:0043229 intracellular organelle 115 115/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/ENO1/AZGP1/PLEC/KRT80/KRT13/HRNR/KRT6B/LMNA/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/TPI1/PRDX1/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/LYZ/TUBA1B/SERPINA1/HSP90AA1/ACTN4/LDHA/CTSD/UBA52/TXN/DMBT1/LGALS7B/BLMH/PLBD1/FLNB/SOD1/HSPB1/HSPA8/EPPK1/PPIA/YWHAZ/GGH/GSTP1/CTSV/ALDOA/CAPN1/VCL/YWHAE/HBB/KRT23/HP/SERPINA3/ORM1/SERPINB1/LCN2/S100A14/GSN/IDE/AGA/PSMA3/EEF1G/MDH2/PNP/CSTB/ALDOC/KRT15/FLG/PERP/SERPINB13/APOD/KLK1/CTSB/RPSA/LAMP1/LAMP2/PPIB/RPS3/ATP5A1/S100A11/CAPG/CAPZB/PSMB3/GDI2/ARPC4/ACTR2/NPC2/CALML5/PIP/MUC7/KRT1/KRT2/KRT10/FLG2/DEFA3/KRT85 +GO:0044422 organelle part 102 102/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/ENO1/PLEC/KRT80/KRT13/HRNR/KRT6B/LMNA/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/LYZ/TUBA1B/SERPINA1/HSP90AA1/ACTN4/CTSD/UBA52/DMBT1/FLNB/SOD1/HSPB1/HSPA8/EPPK1/PPIA/YWHAZ/GGH/GSTP1/CTSV/ALDOA/CAPN1/VCL/YWHAE/HBB/KRT23/HP/SERPINA3/ORM1/SERPINB1/LCN2/S100A14/GSN/IDE/AGA/PSMA3/MDH2/PNP/CSTB/ALDOC/KRT15/FLG/SERPINB13/CTSB/RPSA/LAMP1/LAMP2/PPIB/RPS3/ATP5A1/S100A11/CAPG/CAPZB/PSMB3/GDI2/ARPC4/ACTR2/NPC2/CALML5/MUC7/KRT1/KRT2/KRT10/FLG2/DEFA3/KRT85 +GO:0097597 ventral disc 0 0/153 +GO:0099572 postsynaptic specialization 1 1/153 ACTR2 +GO:0018995 host 0 0/153 +GO:0044217 other organism part 0 0/153 +GO:0033643 host cell part 0 0/153 +GO:0043655 extracellular space of host 0 0/153 +GO:0044216 other organism cell 0 0/153 +GO:0044279 other organism membrane 0 0/153 +GO:0085036 extrahaustorial matrix 0 0/153 +GO:0085040 extra-invasive hyphal space 0 0/153 +GO:0005577 fibrinogen complex 0 0/153 +GO:0005601 classical-complement-pathway C3/C5 convertase complex 0 0/153 +GO:0005602 complement component C1 complex 0 0/153 +GO:0005615 extracellular space 78 78/153 ALB/ANXA2/LTF/MUC5B/SERPINB3/ACTG1/KRT78/PIGR/ENO1/AZGP1/ANXA1/TF/CAT/SFN/SERPINB12/TPI1/PRDX1/CSTA/ARG1/HSPA1A/HSPA1B/SERPINB7/LYZ/SERPINA1/IL36G/ACTN4/CTSD/UBA52/DMBT1/CPA4/LGALS7B/PLBD1/SOD1/HSPB1/HSPA8/PPIA/YWHAZ/GGH/GSTP1/LCN1/SERPINB4/CTSV/PGK1/ALDOA/HBB/A2ML1/HP/SERPINA3/ORM1/IL1RN/SERPINB1/LCN2/GSN/IDE/AGA/SERPINB5/LYPD3/CSTB/SERPINB13/APOD/CTSB/LAMP2/S100A11/NPC2/AMY1A/AMY1B/AMY1C/PIP/ZG16B/CST4/CST1/CST2/KRT1/KRT2/KRT10/SERPINA12/DEFA3/KRT85 +GO:0005616 larval serum protein complex 0 0/153 +GO:0016942 insulin-like growth factor binding protein complex 0 0/153 +GO:0020004 symbiont-containing vacuolar space 0 0/153 +GO:0020005 symbiont-containing vacuole membrane 0 0/153 +GO:0020006 symbiont-containing vacuolar membrane network 0 0/153 +GO:0031395 bursicon neuropeptide hormone complex 0 0/153 +GO:0032311 angiogenin-PRI complex 0 0/153 +GO:0034358 plasma lipoprotein particle 0 0/153 +GO:0035182 female germline ring canal outer rim 0 0/153 +GO:0035183 female germline ring canal inner rim 0 0/153 +GO:0036117 hyaluranon cable 0 0/153 +GO:0042571 immunoglobulin complex, circulating 0 0/153 +GO:0043245 extraorganismal space 0 0/153 +GO:0043511 inhibin complex 0 0/153 +GO:0043514 interleukin-12 complex 0 0/153 +GO:0044420 extracellular matrix component 1 1/153 ANXA2 +GO:0045171 intercellular bridge 0 0/153 +GO:0048180 activin complex 0 0/153 +GO:0061696 pituitary gonadotropin complex 0 0/153 +GO:0070289 extracellular ferritin complex 0 0/153 +GO:0070701 mucus layer 1 1/153 MUC5B +GO:0070743 interleukin-23 complex 0 0/153 +GO:0070744 interleukin-27 complex 0 0/153 +GO:0070745 interleukin-35 complex 0 0/153 +GO:0072562 blood microparticle 13 13/153 ALB/ACTG1/TF/HSPA1A/HSPA1B/HSPA8/YWHAZ/HBB/HP/SERPINA3/ORM1/GSN/KRT1 +GO:0097058 CRLF-CLCF1 complex 0 0/153 +GO:0097059 CNTFR-CLCF1 complex 0 0/153 +GO:0097619 PTEX complex 0 0/153 +GO:1990296 scaffoldin complex 0 0/153 +GO:1990563 extracellular exosome complex 0 0/153 +GO:1990903 extracellular ribonucleoprotein complex 0 0/153 +GO:0030094 plasma membrane-derived photosystem I 0 0/153 +GO:0030096 plasma membrane-derived thylakoid photosystem II 0 0/153 +GO:0031300 intrinsic component of organelle membrane 1 1/153 LAMP2 +GO:0031676 plasma membrane-derived thylakoid membrane 0 0/153 +GO:0032420 stereocilium 0 0/153 +GO:0032426 stereocilium tip 0 0/153 +GO:0044232 organelle membrane contact site 0 0/153 +GO:0044441 ciliary part 0 0/153 +GO:0044446 intracellular organelle part 100 100/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/KRT80/KRT13/HRNR/KRT6B/LMNA/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/LYZ/TUBA1B/SERPINA1/HSP90AA1/ACTN4/CTSD/UBA52/DMBT1/FLNB/SOD1/HSPB1/HSPA8/EPPK1/PPIA/YWHAZ/GGH/GSTP1/CTSV/ALDOA/CAPN1/VCL/YWHAE/HBB/KRT23/HP/SERPINA3/ORM1/SERPINB1/LCN2/S100A14/GSN/IDE/AGA/PSMA3/MDH2/PNP/CSTB/ALDOC/KRT15/FLG/SERPINB13/CTSB/RPSA/LAMP1/LAMP2/PPIB/RPS3/ATP5A1/S100A11/CAPG/CAPZB/PSMB3/GDI2/ARPC4/ACTR2/NPC2/CALML5/MUC7/KRT1/KRT2/KRT10/FLG2/DEFA3/KRT85 +GO:0044449 contractile fiber part 9 9/153 JUP/ENO1/PLEC/ACTN4/FLNB/HSPB1/ALDOA/VCL/CAPZB +GO:0044461 bacterial-type flagellum part 0 0/153 +GO:0044695 Dsc E3 ubiquitin ligase complex 0 0/153 +GO:0048493 plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex 0 0/153 +GO:0060091 kinocilium 0 0/153 +GO:0060171 stereocilium membrane 0 0/153 +GO:0097591 ventral disc lateral crest 0 0/153 +GO:0097592 ventral disc overlap zone 0 0/153 +GO:0097593 ventral disc microtubule array 0 0/153 +GO:0097594 ventral disc dorsal microribbon 0 0/153 +GO:0097595 ventral disc crossbridge 0 0/153 +GO:0097596 ventral disc supernumerary microtubule array 0 0/153 +GO:0098576 lumenal side of membrane 1 1/153 HSPA8 +GO:0098892 extrinsic component of postsynaptic specialization membrane 0 0/153 +GO:0098948 intrinsic component of postsynaptic specialization membrane 0 0/153 +GO:0099091 postsynaptic specialization, intracellular component 0 0/153 +GO:0099092 postsynaptic density, intracellular component 0 0/153 +GO:0099634 postsynaptic specialization membrane 0 0/153 +GO:1990070 TRAPPI protein complex 0 0/153 +GO:1990121 H-NS complex 0 0/153 +GO:1990177 IHF-DNA complex 0 0/153 +GO:1990178 HU-DNA complex 0 0/153 +GO:1990500 eif4e-cup complex 0 0/153 +GO:0019013 viral nucleocapsid 0 0/153 +GO:0019015 viral genome 0 0/153 +GO:0019028 viral capsid 0 0/153 +GO:0019033 viral tegument 0 0/153 +GO:0036338 viral membrane 0 0/153 +GO:0039624 viral outer capsid 0 0/153 +GO:0039625 viral inner capsid 0 0/153 +GO:0039626 viral intermediate capsid 0 0/153 +GO:0046727 capsomere 0 0/153 +GO:0046729 viral procapsid 0 0/153 +GO:0046798 viral portal complex 0 0/153 +GO:0046806 viral scaffold 0 0/153 +GO:0098015 virus tail 0 0/153 +GO:0098019 virus tail, major subunit 0 0/153 +GO:0098020 virus tail, minor subunit 0 0/153 +GO:0098021 viral capsid, decoration 0 0/153 +GO:0098023 virus tail, tip 0 0/153 +GO:0098024 virus tail, fiber 0 0/153 +GO:0098025 virus tail, baseplate 0 0/153 +GO:0098026 virus tail, tube 0 0/153 +GO:0098027 virus tail, sheath 0 0/153 +GO:0098028 virus tail, shaft 0 0/153 +GO:0098029 icosahedral viral capsid, spike 0 0/153 +GO:0098030 icosahedral viral capsid, neck 0 0/153 +GO:0098031 icosahedral viral capsid, collar 0 0/153 +GO:0098061 viral capsid, internal space 0 0/153 +GO:0000136 alpha-1,6-mannosyltransferase complex 0 0/153 +GO:0019898 extrinsic component of membrane 6 6/153 ANXA2/JUP/TGM3/ANXA1/TF/DMBT1 +GO:0000835 ER ubiquitin ligase complex 0 0/153 +GO:0005640 nuclear outer membrane 0 0/153 +GO:0005942 phosphatidylinositol 3-kinase complex 0 0/153 +GO:0008250 oligosaccharyltransferase complex 0 0/153 +GO:0009654 photosystem II oxygen evolving complex 0 0/153 +GO:0009923 fatty acid elongase complex 0 0/153 +GO:0030964 NADH dehydrogenase complex 0 0/153 +GO:0031211 endoplasmic reticulum palmitoyltransferase complex 0 0/153 +GO:0031224 intrinsic component of membrane 10 10/153 DSG1/PIGR/HSPA5/MYH9/FLNB/DSC3/LYPD3/PERP/LAMP1/LAMP2 +GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex 0 0/153 +GO:0042765 GPI-anchor transamidase complex 0 0/153 +GO:0044453 nuclear membrane part 0 0/153 +GO:0044455 mitochondrial membrane part 1 1/153 ATP5A1 +GO:0044459 plasma membrane part 17 17/153 DSP/DSG1/ANXA2/JUP/PIGR/TGM3/ANXA1/TF/MYH9/HSP90AA1/EPPK1/CTSV/LYPD3/PERP/LAMP1/RPS3/PIP +GO:0045281 succinate dehydrogenase complex 0 0/153 +GO:0046696 lipopolysaccharide receptor complex 0 0/153 +GO:0070057 prospore membrane spindle pole body attachment site 0 0/153 +GO:0070469 respiratory chain 0 0/153 +GO:0071595 Nem1-Spo7 phosphatase complex 0 0/153 +GO:0097478 leaflet of membrane bilayer 0 0/153 +GO:1902495 transmembrane transporter complex 0 0/153 +GO:1990332 Ire1 complex 0 0/153 +GO:0008021 synaptic vesicle 1 1/153 LAMP1 +GO:0030129 clathrin coat of synaptic vesicle 0 0/153 +GO:0030672 synaptic vesicle membrane 0 0/153 +GO:0034592 synaptic vesicle lumen 0 0/153 +GO:0044326 dendritic spine neck 0 0/153 +GO:0044327 dendritic spine head 0 0/153 +GO:0048786 presynaptic active zone 0 0/153 +GO:0061846 dendritic spine cytoplasm 0 0/153 +GO:0071212 subsynaptic reticulum 0 0/153 +GO:0097060 synaptic membrane 0 0/153 +GO:0097444 spine apparatus 0 0/153 +GO:0097445 presynaptic active zone dense projection 0 0/153 +GO:0098563 intrinsic component of synaptic vesicle membrane 0 0/153 +GO:0098682 arciform density 0 0/153 +GO:0098793 presynapse 2 2/153 HSPA8/LAMP1 +GO:0098794 postsynapse 1 1/153 ACTR2 +GO:0098830 presynaptic endosome 0 0/153 +GO:0098831 presynaptic active zone cytoplasmic component 0 0/153 +GO:0098833 presynaptic endocytic zone 0 0/153 +GO:0098834 presynaptic endocytic zone cytoplasmic component 0 0/153 +GO:0098843 postsynaptic endocytic zone 0 0/153 +GO:0098845 postsynaptic endosome 0 0/153 +GO:0098850 extrinsic component of synaptic vesicle membrane 0 0/153 +GO:0098888 extrinsic component of presynaptic membrane 0 0/153 +GO:0098889 intrinsic component of presynaptic membrane 0 0/153 +GO:0098890 extrinsic component of postsynaptic membrane 0 0/153 +GO:0098895 postsynaptic endosome membrane 0 0/153 +GO:0098897 spine apparatus membrane 0 0/153 +GO:0098899 spine apparatus lumen 0 0/153 +GO:0098929 extrinsic component of spine apparatus membrane 0 0/153 +GO:0098936 intrinsic component of postsynaptic membrane 0 0/153 +GO:0098949 intrinsic component of postsynaptic endosome membrane 0 0/153 +GO:0098952 intrinsic component of spine apparatus membrane 0 0/153 +GO:0098954 presynaptic endosome membrane 0 0/153 +GO:0098955 intrinsic component of presynaptic endosome membrane 0 0/153 +GO:0098965 extracellular matrix of synaptic cleft 0 0/153 +GO:0098999 extrinsic component of postsynaptic endosome membrane 0 0/153 +GO:0099007 extrinsic component of presynaptic endosome membrane 0 0/153 +GO:0099523 presynaptic cytosol 0 0/153 +GO:0099524 postsynaptic cytosol 0 0/153 +GO:0099569 presynaptic cytoskeleton 0 0/153 +GO:0099571 postsynaptic cytoskeleton 0 0/153 +GO:0099631 postsynaptic endocytic zone cytoplasmic component 0 0/153 +GO:1990013 presynaptic grid 0 0/153 +GO:1990780 cytoplasmic side of dendritic spine plasma membrane 0 0/153 +GO:0005622 intracellular 133 133/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/ENO1/AZGP1/PLEC/KRT80/TGM3/KRT13/HRNR/KRT6B/LMNA/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/TPI1/PRDX1/CSTA/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/SERPINB7/LYZ/TUBA1B/SERPINA1/HSP90AA1/ACTN4/GGCT/LDHA/CTSD/UBA52/TXN/DMBT1/LGALS7B/BLMH/PLBD1/FLNB/SOD1/HSPB1/HSPA8/EPPK1/EIF4A1/PPIA/YWHAZ/GGH/ALOX12B/GSTP1/SERPINB4/DSC3/C1orf68/CTSV/PGK1/ALDOA/CAPN1/VCL/YWHAE/HBB/KRT23/HP/SERPINA3/ORM1/IL1RN/SPRR1B/SERPINB1/LCN2/S100A14/GSN/IDE/AGA/PSMA3/EEF1G/SERPINB5/MDH2/PNP/CSTB/ALDOC/KRT15/FLG/PERP/SERPINB13/APOD/KLK1/CTSB/RPSA/LAMP1/LAMP2/TYMP/PPIB/RPS3/ATP5A1/S100A11/CAPG/HAL/CAPZB/GSS/PSMB3/GDI2/ARPC4/ACTR2/NPC2/CALML5/PIP/MUC7/KRT1/KRT2/KRT10/FLG2/KPRP/SPRR2E/DEFA3/KRT85 +GO:0005642 annulate lamellae 0 0/153 +GO:0005905 clathrin-coated pit 1 1/153 TF +GO:0005933 cellular bud 0 0/153 +GO:0005966 cyclic-nucleotide phosphodiesterase complex 0 0/153 +GO:0008287 protein serine/threonine phosphatase complex 0 0/153 +GO:0009344 nitrite reductase complex [NAD(P)H] 0 0/153 +GO:0009347 aspartate carbamoyltransferase complex 0 0/153 +GO:0009349 riboflavin synthase complex 0 0/153 +GO:0009358 polyphosphate kinase complex 0 0/153 +GO:0009930 longitudinal side of cell surface 0 0/153 +GO:0009986 cell surface 10 10/153 ANXA2/LTF/ENO1/ANXA1/HSPA5/TF/MYH9/CTSV/IDE/LAMP1 +GO:0012505 endomembrane system 69 69/153 DSP/ALB/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/FABP5/PIGR/HRNR/LMNA/ANXA1/HSPA5/TF/CAT/S100A7/SERPINB12/PKM/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/TUBB4B/LYZ/SERPINA1/HSP90AA1/ACTN4/CTSD/UBA52/DMBT1/SOD1/HSPA8/PPIA/GGH/GSTP1/CTSV/ALDOA/CAPN1/VCL/HBB/HP/SERPINA3/ORM1/SERPINB1/LCN2/GSN/AGA/EEF1G/PNP/CSTB/ALDOC/PERP/APOD/CTSB/LAMP1/LAMP2/PPIB/RPS3/S100A11/GDI2/ACTR2/NPC2/CALML5/MUC7/KRT1/FLG2/DEFA3 +GO:0015627 type II protein secretion system complex 0 0/153 +GO:0019008 molybdopterin synthase complex 0 0/153 +GO:0020007 apical complex 0 0/153 +GO:0020008 rhoptry 0 0/153 +GO:0020031 polar ring of apical complex 0 0/153 +GO:0020032 basal ring of apical complex 0 0/153 +GO:0020039 pellicle 0 0/153 +GO:0030256 type I protein secretion system complex 0 0/153 +GO:0030257 type III protein secretion system complex 0 0/153 +GO:0030312 external encapsulating structure 0 0/153 +GO:0030427 site of polarized growth 1 1/153 YWHAE +GO:0030428 cell septum 0 0/153 +GO:0030496 midbody 3 3/153 ANXA2/HSPA5/CAPG +GO:0030904 retromer complex 0 0/153 +GO:0030905 retromer, tubulation complex 0 0/153 +GO:0030906 retromer, cargo-selective complex 0 0/153 +GO:0031252 cell leading edge 7 7/153 ANXA2/MYH9/HSP90AA1/GSN/RPS3/S100A11/ACTR2 +GO:0031254 cell trailing edge 1 1/153 MYH9 +GO:0031317 tripartite ATP-independent periplasmic transporter complex 0 0/153 +GO:0031521 spitzenkorper 0 0/153 +GO:0031522 cell envelope Sec protein transport complex 0 0/153 +GO:0031975 envelope 10 10/153 LMNA/ANXA1/CAT/ARG1/GAPDH/UBA52/SOD1/MDH2/RPS3/ATP5A1 +GO:0032126 eisosome 0 0/153 +GO:0032153 cell division site 1 1/153 MYH9 +GO:0032155 cell division site part 1 1/153 MYH9 +GO:0032179 germ tube 0 0/153 +GO:0032766 NHE3/E3KARP/ACTN4 complex 0 0/153 +GO:0033016 rhoptry membrane 0 0/153 +GO:0033104 type VI protein secretion system complex 0 0/153 +GO:0033774 basal labyrinth 0 0/153 +GO:0034591 rhoptry lumen 0 0/153 +GO:0035748 myelin sheath abaxonal region 0 0/153 +GO:0035749 myelin sheath adaxonal region 1 1/153 ANXA2 +GO:0036375 Kibra-Ex-Mer complex 0 0/153 +GO:0042597 periplasmic space 0 0/153 +GO:0042763 intracellular immature spore 0 0/153 +GO:0042995 cell projection 20 20/153 ANXA2/ANXA1/PKM/ARG1/MYH9/HSP90AA1/ACTN4/FLNB/SOD1/HSPB1/EPPK1/CTSV/YWHAE/GSN/APOD/LAMP1/RPS3/S100A11/ARPC4/ACTR2 +GO:0043209 myelin sheath 15 15/153 ALB/ANXA2/ACTG1/HSPA5/PKM/PRDX1/TUBB4B/TUBA1B/HSP90AA1/SOD1/HSPA8/GSN/MDH2/ATP5A1/GDI2 +GO:0043218 compact myelin 1 1/153 ANXA2 +GO:0043219 lateral loop 0 0/153 +GO:0043220 Schmidt-Lanterman incisure 1 1/153 ANXA2 +GO:0043684 type IV secretion system complex 0 0/153 +GO:0044099 polar tube 0 0/153 +GO:0044297 cell body 6 6/153 ARG1/FLNB/SOD1/CTSV/APOD/LAMP1 +GO:0044424 intracellular part 133 133/153 DSP/KRT6A/ALB/KRT16/DSG1/ANXA2/JUP/LTF/MUC5B/SERPINB3/ACTG1/KRT78/KRT17/FABP5/CASP14/PIGR/ENO1/AZGP1/PLEC/KRT80/TGM3/KRT13/HRNR/KRT6B/LMNA/ANXA1/HSPA5/TF/CAT/S100A7/SFN/SERPINB12/PKM/TPI1/PRDX1/CSTA/ARG1/GAPDH/HSPA1A/HSPA1B/EEF2/MYH9/TUBB4B/SERPINB7/LYZ/TUBA1B/SERPINA1/HSP90AA1/ACTN4/GGCT/LDHA/CTSD/UBA52/TXN/DMBT1/LGALS7B/BLMH/PLBD1/FLNB/SOD1/HSPB1/HSPA8/EPPK1/EIF4A1/PPIA/YWHAZ/GGH/ALOX12B/GSTP1/SERPINB4/DSC3/C1orf68/CTSV/PGK1/ALDOA/CAPN1/VCL/YWHAE/HBB/KRT23/HP/SERPINA3/ORM1/IL1RN/SPRR1B/SERPINB1/LCN2/S100A14/GSN/IDE/AGA/PSMA3/EEF1G/SERPINB5/MDH2/PNP/CSTB/ALDOC/KRT15/FLG/PERP/SERPINB13/APOD/KLK1/CTSB/RPSA/LAMP1/LAMP2/TYMP/PPIB/RPS3/ATP5A1/S100A11/CAPG/HAL/CAPZB/GSS/PSMB3/GDI2/ARPC4/ACTR2/NPC2/CALML5/PIP/MUC7/KRT1/KRT2/KRT10/FLG2/KPRP/SPRR2E/DEFA3/KRT85 +GO:0044457 cell septum part 0 0/153 +GO:0044462 external encapsulating structure part 0 0/153 +GO:0044463 cell projection part 5 5/153 HSP90AA1/SOD1/HSPB1/YWHAE/RPS3 +GO:0044697 HICS complex 0 0/153 +GO:0045177 apical part of cell 5 5/153 DSG1/ANXA1/TF/CTSV/PIP +GO:0045178 basal part of cell 1 1/153 TF +GO:0051286 cell tip 0 0/153 +GO:0060187 cell pole 0 0/153 +GO:0061835 ventral surface of cell 0 0/153 +GO:0070056 prospore membrane leading edge 0 0/153 +GO:0070258 inner membrane complex 0 0/153 +GO:0070331 CD20-Lck-Fyn complex 0 0/153 +GO:0070332 CD20-Lck-Lyn-Fyn complex 0 0/153 +GO:0070938 contractile ring 1 1/153 MYH9 +GO:0071944 cell periphery 59 59/153 DSP/DSG1/ANXA2/JUP/MUC5B/ACTG1/KRT17/FABP5/PIGR/ENO1/AZGP1/PLEC/TGM3/HRNR/ANXA1/HSPA5/TF/CAT/SERPINB12/CSTA/GAPDH/EEF2/MYH9/HSP90AA1/ACTN4/UBA52/FLNB/SOD1/HSPB1/HSPA8/EPPK1/GSTP1/DSC3/C1orf68/CTSV/CAPN1/VCL/YWHAE/IL1RN/SPRR1B/CST6/GSN/IDE/LYPD3/FLG/PERP/RPSA/LAMP1/LAMP2/RPS3/ATP5A1/ACTR2/PIP/MUC7/KRT1/KRT2/KRT10/SERPINA12/SPRR2E +GO:0072324 ascus epiplasm 0 0/153 +GO:0090543 Flemming body 1 1/153 CAPG +GO:0090635 extracellular core region of desmosome 0 0/153 +GO:0090636 outer dense plaque of desmosome 0 0/153 +GO:0090637 inner dense plaque of desmosome 0 0/153 +GO:0097223 sperm part 0 0/153 +GO:0097268 cytoophidium 0 0/153 +GO:0097458 neuron part 10 10/153 ARG1/ACTN4/FLNB/SOD1/HSPB1/HSPA8/CTSV/YWHAE/APOD/LAMP1 +GO:0097569 lateral shield 0 0/153 +GO:0097574 lateral part of cell 0 0/153 +GO:0097610 cell surface furrow 1 1/153 MYH9 +GO:0097613 dinoflagellate epicone 0 0/153 +GO:0097614 dinoflagellate hypocone 0 0/153 +GO:0097653 unencapsulated part of cell 0 0/153 +GO:0097683 dinoflagellate apex 0 0/153 +GO:0097684 dinoflagellate antapex 0 0/153 +GO:0098046 type V protein secretion system complex 0 0/153 +GO:0098862 cluster of actin-based cell projections 4 4/153 PLEC/MYH9/ACTN4/FLNB +GO:1990015 ensheathing process 0 0/153 +GO:1990016 neck portion of tanycyte 0 0/153 +GO:1990018 tail portion of tanycyte 0 0/153 +GO:1990225 rhoptry neck 0 0/153 +GO:1990794 basolateral part of cell 0 0/153 +GO:0031594 neuromuscular junction 1 1/153 MYH9 +GO:0044456 synapse part 3 3/153 HSPA8/LAMP1/ACTR2 +GO:0060076 excitatory synapse 0 0/153 +GO:0060077 inhibitory synapse 0 0/153 +GO:0097470 ribbon synapse 0 0/153 +GO:0098685 Schaffer collateral - CA1 synapse 0 0/153 +GO:0098686 hippocampal mossy fiber to CA3 synapse 0 0/153 +GO:0098978 glutamatergic synapse 0 0/153 +GO:0098979 polyadic synapse 0 0/153 +GO:0098981 cholinergic synapse 0 0/153 +GO:0098982 GABA-ergic synapse 0 0/153 +GO:0098984 neuron to neuron synapse 1 1/153 ACTR2 +GO:0009506 plasmodesma 0 0/153 +GO:0005818 aster 0 0/153 +GO:0097740 paraflagellar rod 0 0/153 +GO:0097741 mastigoneme 0 0/153 +GO:0098644 complex of collagen trimers 0 0/153 +GO:0099081 supramolecular polymer 30 30/153 DSP/KRT6A/KRT16/JUP/ACTG1/KRT78/KRT17/CASP14/ENO1/PLEC/KRT80/KRT13/KRT6B/LMNA/TUBB4B/TUBA1B/ACTN4/FLNB/HSPB1/EPPK1/ALDOA/VCL/KRT23/KRT15/FLG/CAPZB/KRT1/KRT2/KRT10/KRT85