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author | rnateam |
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date | Sun, 03 Dec 2023 12:51:54 +0000 |
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1 <p><head> | |
2 <title>RBPBench - Motif Search Comparison Report</title></p> | |
3 <script src="/home/malong/miniconda3/envs/rbpbench/lib/python3.9/site-packages/rbpbench/content/sorttable.js" type="text/javascript"></script> | |
4 <p></head></p> | |
5 <h1>Comparison Report</h1> | |
6 <p>List of available comparison statistics generated | |
7 by RBPBench (rbpbench compare):</p> | |
8 <ul> | |
9 <li><a href="#method-tab-1">k562_eclip,human_v0.1,PUM1 method comparison table</a></li> | |
10 <li><a href="#method-tab-2">k562_eclip,human_v0.1,PUM2 method comparison table</a></li> | |
11 <li><a href="#method-venn-1">k562_eclip,human_v0.1,PUM1 method comparison plot</a></li> | |
12 <li><a href="#method-venn-2">k562_eclip,human_v0.1,PUM2 method comparison plot</a></li> | |
13 </ul> | |
14 <p> </p> | |
15 <h2 id="method-tab-1">k562_eclip,human_v0.1,PUM1 method comparison statistics</h2> | |
16 <p><strong>Table:</strong> RBP motif hit statistics for combined ID "k562_eclip,human_v0.1,PUM1" (data ID, motif database ID, RBP ID) over different methods (method ID column).</p> | |
17 <table class="sortable"> | |
18 <thead> | |
19 <tr> | |
20 <th style="text-align: center;">Method ID</th> | |
21 <th style="text-align: center;"># regions</th> | |
22 <th style="text-align: center;"># motif hits</th> | |
23 <th style="text-align: center;">% regions with motifs</th> | |
24 <th style="text-align: center;">% motif nucleotides</th> | |
25 <th style="text-align: center;"># motif hits per 1000 nt</th> | |
26 </tr> | |
27 </thead> | |
28 <tbody> | |
29 <tr> | |
30 <td style="text-align: center;">dewseq_w100_s5</td> | |
31 <td style="text-align: center;">23</td> | |
32 <td style="text-align: center;">24</td> | |
33 <td style="text-align: center;">43.48</td> | |
34 <td style="text-align: center;">3.20</td> | |
35 <td style="text-align: center;">4.86</td> | |
36 </tr> | |
37 <tr> | |
38 <td style="text-align: center;">clipper_idr</td> | |
39 <td style="text-align: center;">32</td> | |
40 <td style="text-align: center;">8</td> | |
41 <td style="text-align: center;">18.75</td> | |
42 <td style="text-align: center;">2.69</td> | |
43 <td style="text-align: center;">3.84</td> | |
44 </tr> | |
45 </tbody> | |
46 </table> | |
47 <p> | |
48 </p> | |
49 <p>Column IDs have the following meanings: <strong>Method ID</strong> -> method ID set for dataset (typically peak calling method ID), <strong># regions</strong> -> number of peak regions used for motif search, <strong># motif hits</strong> -> number of unique motif hits in peak regions (removed double counts), <strong>% regions with motifs</strong> -> percentage of peak regions with motif hits, <strong>% motif nucleotides</strong> -> percentage of unique motif nucleotides over effective peak region size (overlapping regions merged), <strong># motif hits per 1000 nt</strong> -> number of motif hits over 1000 nt of called peak region size (overlapping regions NOT merged).</p> | |
50 <h2 id="method-tab-2">k562_eclip,human_v0.1,PUM2 method comparison statistics</h2> | |
51 <p><strong>Table:</strong> RBP motif hit statistics for combined ID "k562_eclip,human_v0.1,PUM2" (data ID, motif database ID, RBP ID) over different methods (method ID column).</p> | |
52 <table class="sortable"> | |
53 <thead> | |
54 <tr> | |
55 <th style="text-align: center;">Method ID</th> | |
56 <th style="text-align: center;"># regions</th> | |
57 <th style="text-align: center;"># motif hits</th> | |
58 <th style="text-align: center;">% regions with motifs</th> | |
59 <th style="text-align: center;">% motif nucleotides</th> | |
60 <th style="text-align: center;"># motif hits per 1000 nt</th> | |
61 </tr> | |
62 </thead> | |
63 <tbody> | |
64 <tr> | |
65 <td style="text-align: center;">dewseq_w100_s5</td> | |
66 <td style="text-align: center;">70</td> | |
67 <td style="text-align: center;">448</td> | |
68 <td style="text-align: center;">92.86</td> | |
69 <td style="text-align: center;">14.08</td> | |
70 <td style="text-align: center;">31.46</td> | |
71 </tr> | |
72 <tr> | |
73 <td style="text-align: center;">clipper_idr</td> | |
74 <td style="text-align: center;">77</td> | |
75 <td style="text-align: center;">219</td> | |
76 <td style="text-align: center;">76.62</td> | |
77 <td style="text-align: center;">17.64</td> | |
78 <td style="text-align: center;">46.89</td> | |
79 </tr> | |
80 </tbody> | |
81 </table> | |
82 <p> | |
83 </p> | |
84 <p>Column IDs have the following meanings: <strong>Method ID</strong> -> method ID set for dataset (typically peak calling method ID), <strong># regions</strong> -> number of peak regions used for motif search, <strong># motif hits</strong> -> number of unique motif hits in peak regions (removed double counts), <strong>% regions with motifs</strong> -> percentage of peak regions with motif hits, <strong>% motif nucleotides</strong> -> percentage of unique motif nucleotides over effective peak region size (overlapping regions merged), <strong># motif hits per 1000 nt</strong> -> number of motif hits over 1000 nt of called peak region size (overlapping regions NOT merged).</p> | |
85 <h2 id="method-venn-1">k562_eclip,human_v0.1,PUM1 method comparison plot</h2> | |
86 <p>Based on the same combined ID "k562_eclip,human_v0.1,PUM1" (data ID, motif database ID, RBP ID), motif hit occurrences for 2 different methods (clipper_idr,dewseq_w100_s5) are compared via Venn diagram. | |
87 Any given motif hit can either be found only by one method, or be identified by any set (>=2) of methods (intersection areas).</p> | |
88 <p><img src="html_report_plots/venn_diagram.method_comp.k562_eclip,human_v0.1,PUM1.png" alt="dataset comparison plot k562_eclip,human_v0.1,PUM1 | |
89 title="dataset comparison plot k562_eclip,human_v0.1,PUM1" width="700" /></p> | |
90 <p><strong>Figure:</strong> Venn diagram of motif hit occurrences for 2 different methods (clipper_idr,dewseq_w100_s5) with identical combined ID (k562_eclip,human_v0.1,PUM1) + corresponding percentages of total motif hits for each region (method exclusive and intersection(s)).</p> | |
91 <p> </p> | |
92 <h2 id="method-venn-2">k562_eclip,human_v0.1,PUM2 method comparison plot</h2> | |
93 <p>Based on the same combined ID "k562_eclip,human_v0.1,PUM2" (data ID, motif database ID, RBP ID), motif hit occurrences for 2 different methods (clipper_idr,dewseq_w100_s5) are compared via Venn diagram. | |
94 Any given motif hit can either be found only by one method, or be identified by any set (>=2) of methods (intersection areas).</p> | |
95 <p><img src="html_report_plots/venn_diagram.method_comp.k562_eclip,human_v0.1,PUM2.png" alt="dataset comparison plot k562_eclip,human_v0.1,PUM2 | |
96 title="dataset comparison plot k562_eclip,human_v0.1,PUM2" width="700" /></p> | |
97 <p><strong>Figure:</strong> Venn diagram of motif hit occurrences for 2 different methods (clipper_idr,dewseq_w100_s5) with identical combined ID (k562_eclip,human_v0.1,PUM2) + corresponding percentages of total motif hits for each region (method exclusive and intersection(s)).</p> | |
98 <p> </p> |