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changeset 0:cd00b4fe6552 draft

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Imported from capsule None
author rnateam
date Mon, 22 Dec 2014 09:08:31 -0500
parents
children 5a4b00c84f50
files rnabob.xml test-data/F22B7.fa test-data/r17.bob test-data/r17.des test-data/trna.bob test-data/trna.des tool_dependencies.xml
diffstat 7 files changed, 1083 insertions(+), 0 deletions(-) [+]
line wrap: on
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--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/rnabob.xml	Mon Dec 22 09:08:31 2014 -0500
@@ -0,0 +1,218 @@
+<tool id="rbc_rnabob" name="RNABOB" version="2.2.1.0">
+    <description>Fast Pattern searching for RNA secondary structures</description>
+    <requirements>
+        <requirement type="package" version="2.2.1">rnabob</requirement>
+    </requirements>
+    <version_command>echo "2.2.1"</version_command>
+    <command>
+<![CDATA[
+    rnabob 
+    	-q
+    	$fancy
+    	$compStrands
+    	$skipOverlapping
+    	$descriptorFile
+    	$sequenceFile > $stdout
+]]>
+    </command>
+    <stdio>
+        <exit_code range="1:" level="fatal" description="Error occurred. Please check Tool Standard Error" />
+        <exit_code range=":-1" level="fatal" description="Error occurred. Please check Tool Standard Error" />
+    </stdio>
+    <inputs>
+        <param name="descriptorFile" type="data" format="txt" multiple="false" label="Motif Descriptor File" help="This file contains the description of the motif for which to search"/>
+	    <param name="sequenceFile" type="data" format="fasta" multiple="false" label="Sequence File" help="This file specifies the sequence in which the motif will be searched"/>
+	    <param name="compStrands" type="boolean" truevalue="-c" falsevalue="" checked="false" label="Also search on complementary strands" help="-c : Search both strands of the supplied sequence"/>
+	    <param name="skipOverlapping" type="boolean" truevalue="-s" falsevalue="" checked="false" label="Skip overlapping matches" help="-s : This is a workaround to avoid a problem in the DNABANK, overlapping matches will be ignored"/>
+	    <param name="fancy" type="boolean" checked="false" truevalue="-F" falsevalue="" label="Show Alignments" help="Display full alignments to pattern"/>
+    </inputs>
+    <outputs>
+        <data format="txt" name="stdout" label="${tool.name} on ${on_string}" />
+    </outputs>
+    <tests>
+        <test>
+            <param name="descriptorFile" value="r17.des" />
+            <param name="sequenceFile" value="F22B7.fa" />
+            <param name="compStrands" value="True" />
+            <param name="skipOverlapping" value="False" />
+            <param name="fancy" value="False" />
+            <output name="stdout" file="r17.bob" />
+        </test>
+        <test>
+            <param name="descriptorFile" value="trna.des" />
+            <param name="sequenceFile" value="F22B7.fa" />
+            <param name="compStrands" value="True" />
+            <param name="skipOverlapping" value="False" />
+            <param name="fancy" value="False" />
+            <output name="stdout" file="trna.bob" />
+        </test>
+    </tests>
+    <help>
+**What RNABOB does**
+
+RNABOB allows searching a sequence database for RNA structural motifs.
+The probe motif is specified in a *descriptor* file,
+which describes its primary sequence, secondary structure, and tertiary constraints.
+The source in its original packaging can be found at http://selab.janelia.org/software/#rnabob.
+
+-----
+
+**Sequence database format**
+
+RNABOB is currently restricted to reading sequence files in FASTA format. 
+The command line version of RNABOB can also read sequence files in GCG, EMBL, GenBank and other formats.
+
+-----
+
+**Descriptor file syntax**
+
+The descriptor file syntax is fairly powerful, and allows a great deal of freedom for specifying 
+RNA motifs. The syntax is therefore a bit complicated.
+
+The descriptor file has two parts: a **topology** description and an **explicit** description.
+
+The first non-blank, non-comment line of the file is the topology description. It defines the 
+order of occurrence of a series of single-stranded, double-stranded and related elements. Each 
+element must be given a unique name (a number, typically) and must be prefixed with '**s**', 
+'**h**', or '**r**', indicating single-strand, helical, or a relational element. Helical and 
+relational elements are paired to other elements, which are suffixed by a prime, **\'**.
+
+For example::
+
+	\
+			h1 s1 h1'
+
+describes a hairpin loop structure with a simple helix and single-stranded loop. If the helix 
+always contained a non-canonical base pair at one position, the topology coud be described as::
+
+	\
+			h1 r1 h2 s1 h2' r1' h1'
+
+where r1,r1' indicate a correlation, where the sequence r1 constrains the sequence of r1'. 
+(Helices are a special case of this.)
+
+The remaining non-comment, non-blank lines are explicit descriptions of each element in turn. Each 
+line contains 3 or 4 fields, separated by tabs or blank space. The first field is the name of the 
+element, from the topology description. The second field is the number of mismatches allowed in 
+this element. The third field is the primary sequence constraint to apply to this element.
+
+Helices and relational element pairs are specified on a single line rather than two. Mismatches 
+and primary sequence constraints are given as pairs, separated by a colon '**:**'. The left side 
+is the constraint applied to the upstream element, and the right side is applied to the downstream 
+elements.
+
+The primary sequence constraint is given as a sequence of nucleotides. Any IUPAC single-letter 
+code is recognized, including N if the position can have any base identity. Allowed length 
+variations are specified with asterisks ``'*'``, where each ``*`` will allow either 0 or 1 N at 
+that position.
+
+For example::
+
+	\
+			GGAGG******NNNAUG
+
+specifies a GGAGG Shine/Dalgarno site and an AUG initiation codon, separated by a spacer of 3 to 9 
+nucleotides of any sequence.
+
+An alternative syntax can be used for very long gaps::
+
+	\
+			GGAGG[10]NNNAUG is the same as GGAGG**********NNNAUG
+
+Be careful defining variable length helices and relational elements; if the number and type (gap 
+or identity) of position do not match on left and right sides, the program will refuse to accept 
+the descriptor.
+
+Relational elements have an additional field which specifies a "transformation matrix" of four 
+nucleotides, specifying the rule for making the ``r'`` pattern from the ``r`` sequence in order 
+``A-C-G-T``. For example, the transformation matrix for a simple helix is ``TGCA``; if you allow 
+``G-U`` pairs, it is ``TGYR``. RNABOB allows ``G-U`` pairing by default and uses the ``TGYR`` 
+matrix for helical elements.
+
+For example, the explicit description of our hairpin might be:
+
+::
+
+	\
+	 		h1 0:0 NNN:NNN
+	 		r1 0:0 R:N GNAN
+	 		h2 0:0 **NC:GN**
+		 	s1 0 UUCG
+
+This describes a stem of 6 to 8 base pairs, in which the 4th pair from the bottom of the stem must 
+be a non-canonical GA pair. Note that, in general, the left side of the primary constraint for 
+helices and relational elements is redundant, and should be given as all N. In some cases it is 
+convenient to constrain the right side to require a particular base pair (GU, for instance) at one 
+position.
+
+A note on mismatches: The split format for helices and relational elements works like this. The 
+number on the left constrains the primary sequence match of the left side of the primary 
+constraint. The number on the right constrains the match of the right side of the primary 
+constraint, *after* that side has been constructed according to the sequence on the left. In other 
+words, the number on the left constrains the mismatches in primary sequence only, while the number 
+on the right will constrain the number of mispaired positions in the helix.
+
+Finally: any line that begins with a pound sign '#' is a comment line, and will not be interpreted 
+by the pattern compiler.
+
+**Options**
+
+The behavior of RNABOB can be modified by use of the following options:
+
+*Complement*: Selecting this option will cause RNABOB to search for the pattern also on the 
+complementary strands.
+
+*Skip*: This is a workaround to avoid a problem in the DNABANK. There are some sequences in the 
+database which have long stretches of ambiguous sequence (N's). Descriptors with no primary 
+sequence constraints will match these garbage sequences at many, many positions, and generate huge 
+outputs. This option toggles a search strategy that skips forward a pattern-length rather than a 
+single base when a match is found, thus printing out only a single match when overlapping matches 
+are found. 
+
+**Examples**
+
+The following example descriptors included in the source distribution 
+(http://selab.janelia.org/software/rnabob/rnabob.tar.gz):
+
+	- trna.des - a general descriptor of a tRNA structure
+	- r17.des - descriptor of the consensus binding site for the r17 phage coat protein
+	- pseudoknot.des - description of a simple pseudoknotted structure
+
+An example cosmid ``F22B7.fa`` from the *C. elegans* genome sequencing project is also provided 
+for running these descriptors against.
+
+::
+
+	\
+		# trna.des
+		#
+		# Generalized descriptor of a tRNA cloverleaf. Doesn't
+		# find them all though. 
+		#
+
+		h1 s1 h2 s2 h2' s3 h3 s4 h3' s5 h4 s6 h4' h1' s8
+
+		h1 0:2 NNNNNNN:NNNNNNN
+		h2 0:1 *NNN:NNN*
+		h3 0:1 NNNNN:NNNNN
+		h4 0:1 NNNNN:NNNNN
+		s1 0 TN
+		s2 0 NNNN**********
+		s3 0 N
+		s4 0 NNNNNN*
+		s5 0 NN********************
+		s6 0 TTC****
+		s8 0 NCCA
+
+Running RNABOB with ``trna.des`` against ``F22B7.fa`` searches the top strand of the cosmid for 
+the above motif. ``trna.des`` hits twice, once on each strand. (F22B7 has several other tRNA genes 
+in it which the pattern fails to detect - this is *not* a pattern to use for tRNA genefinding!).
+    </help> 
+    <citations>
+	<citation type="doi">10.1093/bioinformatics/6.4.325</citation>
+	<citation type="bibtex">@UNPUBLISHED{rnabob,
+author = {Eddy S.R},
+title = {RNABOB: a program to search for RNA secondary structure motifs in sequence databases},
+note = {}}</citation>
+    </citations>
+</tool>
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/F22B7.fa	Mon Dec 22 09:08:31 2014 -0500
@@ -0,0 +1,806 @@
+>F22B7  921215/f22b7.seq
+GATCCTTGTAGATTTTGAATTTGAAGTTTTTTCTCATTCCAAAACTCTGT
+GATCTGAAATAAAATGTCTCAAAAAAATAGAAGAAAACATTGCTTTATAT
+TTATCAGTTATGGTTTTCAAAATTTTCTGACATACCGTTTTGCTTCTTTT
+TTTCTCATCTTCTTCAAATATCAATTGTGATAATCTGACTCCTAACAATC
+GAATTTCTTTTCCTTTTTCTTTTTCCAACAACTCCAGTGAGAACTTTTGA
+ATATCTTCAAGTGACTTCACCACATCAGAAGGTGTCAACGATCTTGTGAG
+AACATCGAATGAAGATAATTTTAATTTTAGAGTTACAGTTTTTCCTCCGA
+CAATTCCTGATTTACGAACATCTTCTTCAAGCATTCTACAGATTTCTTGA
+TGCTCTTCTAGGAGGATGTTGAAATCCGAAGTTGGAGAAAAAGTTCTCTC
+AACTGAAATGCTTTTTCTTCGTGGATCCGATTCAGATGGACGACCTGGCA
+GTCCGAGAGCCGTTCGAAGGAAAGATTCTTGTGAGAGAGGCGTGAAACAC
+AAAGGGTATAGGTTCTTCTTCAGATTCATATCACCAACAGTTTGAATATC
+CATTGCTTTCAGTTGAGCTTCGCATACACGACCAATTCCTCCAACCTAAA
+AAATTATCTAGGTAAAACTAGAAGGTTATGCTTTAATAGTCTCACCTTAC
+GAATCGGTAAATCCTTCAAAAACTCCATAATCGCGTTTTTATCATTTTCT
+AACACATATTGACCATTTGGTTTGTTCAAATCAGAACAAATCTTAGCGAG
+CATAAAGTTAGATGCGATTCCAGCAGAACATGTTAATCCCGTGAGTTGTT
+CAACTCGAAATCGAATTTCTCGAACAGCCTCCTCTCGTCCAGTTCCGAAC
+TCCACATGGTCGTAGTAGATTTTCCGCGATTTTTCGCATTTTGGACAGAT
+CGATTCTTCGATTTTCAAGTCTTCCAAAGTATTTTCATTCTCGTCGAAAC
+GGGGTAACCAACATGGACAATCTCCGCCGAATCTGTGACGCTTGAAGGTT
+TCTAGTAAGCAAATAGTTTTTTGTTAATAATCAAATCTAAATCACTAACT
+TTTTTCTGTATTACTTGCCACATAGTCTGTCAAATCTATAAATGCCTCAT
+CCAATGACATCATTCCAACATCCGAATCGTATTCCATGAAAATTTGTGAA
+AATTGGCGACTGACTTTAGTGTATTTAGGGTAATTTCCTGGAACAATCGT
+TAGACTCGGACAAAGTTTATTTGAGATGAAGCCAGGCATTCCAGCACGGA
+CTCCAAAACGGCGAGCCAAGTAGTTGGATGTGCTCTGAAAGAATAGATTT
+AAAGCTTTTCCGAAATCGAAAATTTACTTTTCAAATTGAGTTAGGTGCTT
+ACCAGCATTGCCGATGAGCCTACGGCCATAGGAACTGTTCTCAGTGCAGG
+ATTATCTCTCATTTCAACTGCGGCAAAATAAGCATCCATATCTATACAAA
+CACAGTCTCTTGATAAATCTCTAGATGATTCCAGTTTCATCTCAAGATTC
+TCCATCTGAAAATTGGAAATTTGCTCTAAGTAAATTTATTAGCTTTTAAA
+ATACATACCAGTATCTCAGATTTTTGTCTTTCTTCTCTGGTTGCTGTTTG
+CAAACGATTTTTGATTTCTAAAACTTTCTCTTCAATTCTTGATTGTTGTT
+TTTTGGAAAACGACGAGTAGGACGCTGATGTGTTTTCTTCGATGACTTTC
+GTGATTTTCTCCTTATCCAGTCCATTCATTCCAGCTTTATTATCGTTGAA
+AGTCAGCATTTTTCACGAAAAAGAGCCGGATTTTGAAATTCGCGGAGAAA
+CTCCACTGATTGTGAGTGTGCAAATGCGCGTAATGGTGTACTTACGTACA
+TCGGCAACACATTTGACGACATATCAGAAAGCGGCGCCAAATTAGAAGTT
+GAGTGCGCGAGAAAAAACTACGCGTTAACCGCCAATTTTCACTTCCCCAC
+AGATCTGTCTCGAGATTCTCGAGTCATTTTTCAAGTTTATTTGTTTGTCA
+GCGGTTGTTTTATTGAAGATTTGTAAAATTTATAACAAAATGTGCAATAG
+TCTATTAAACCTCGTGAGATATTTGAAGAAACTTTCCCCGTTTTAAATAT
+TTCGTGTATTCGTGGAGATCGCGGGAATGTTTTGCCTGTTTCCGTAAAAT
+TCCTCTATTTCTTTTATTTTTGCTTGCAATTTTCGATTCATTTCAGAAGT
+TTCCACATTCGCAAAACGAATGGACGTCTCTTATTACGATGGTCCCAAGG
+ATGAAGTCGCCGAAGCAATGCTGAAAAGCGCGGTGACGGCCATGAGATTG
+GGACAATACGAGGATGGAAAAGGACGCTTAGAGGAGATAATGGAGTTCGG
+AACCTCAAATTTTCAACTACTTGGTACAATCTACATGTATTACGGAAGAG
+TGTGCAGGCATTTGAACCATGATGCCAAGGCCTTGGAGTTTTTCGAACAT
+GAGTTGAACATGTTCAAGTAAGTGAATCACAAAAATGAGCTGGACATTCT
+ATAACCTTAATTTTTCAGATTGATCTTCAACTACCCAGAAGCATGTGATT
+CCACACGTCGCATCGTCGAGCAGGCACTCAAAATGGGAAAGTTCCCCAAG
+GCTCGACGGTTTGCTGAGGATCTCATTGATTACACCAGCAATAAGAAGAA
+CGGAGAGAAGTATATCGGTCAAGCTCGAATTTTGTTCGCTTCCGTGTGCC
+TCGAAGGATGTGAAAGAGACGTCGAGAGTAATCAAGATGAGAAGAAGAAG
+CTTTTGTCAATATGTGCTGAACAGATTGCAGCCGTGAAATTGTTCAACGA
+GAATAATACGGAAGGAGCTGTGTCTGAGACCAAAATCATGTTACTTGAGG
+CGAAATGCTTGTCACTAGACGAAAAATACGAGGAATCGCGTCGCAAGTAT
+CAAGAATGCATCGATTTTGCCATCAAAACAGACCAGTTTGAAGCAGTTCA
+CATCGCCTATTACGACAAGGCTCTATATGCTGAGACAGATCTTCTTTTCT
+TTATTATCAGAGATCTCAGGTAATTTTTAGTTTTAACGATTAATAAAAAT
+ATCAATTCTTTATTCACAGAAGTGCTCTCTTCTACGCCACGAAATTCGGA
+AAAGAGCGAGATGTAGTCAAATATAAGTCGAAGCTATCCGAAGAGATGCT
+GAGAAATGGCGAATTCCACGAAGCATATCTCTACGGATTGGAAGCGCTTG
+TATCGATTCGGAAGCTTGGATTGAACGAATACATTGGAGATGTGTTGCTT
+ACAATCGCAAAGTGCCTCATTGCACTTGGAAAAAGACGCCAAGCTGCTTA
+TTTTATCATCTTGGGGAGTGTTCTGACCATCAACCAAAACAGTTTCAAAC
+TGTTCTACGAGCAGATCGACGTGGCGATGAATCAAGAGAGAAGCGAAACG
+GCAACTGATCAAGATGTATGCCTCGCAATTGATTCGTCTCCTGATCCGAC
+ATCCTCGAATGACATGATTAATAAGTTCGTCGTCGAACTGGAGCACGCAA
+CAAATGTGGAAACCTGGGAAATGATTGTCAACGGAATCATTGACGACCAG
+AAGAAACCAGTGGCGATCGAAAAGAAAGAGAACGAGGAACCCGTAGACAT
+GATGGATCTCATTTTCAGTATGAGCTCACGTATGGATGATCAAAGAACTG
+AACTGCCTGCTGCCAGATTCATTCCGCGTAAGAAATGTTATAAATAAGCG
+TATAAGTATGCAAATTTATATTTTTCCAGCTCGTCCAGTGTCATCGGCAT
+CGAAAAAGACTACAAAGAGTCACAGAATCCTCCCTGGACTCCGTGCCAAT
+TGGACAAAAGTGCAGTCGATGAAGTTCGATGGTCACACAATGAATAGGAT
+CCTGAAGAGGTCGAAGAAAAGCAAATCGTCATTGGATTCTACAAATTCGA
+TGCAGGGCGATGATACTCGAAGCGATGATGTGACAATGACGTCCAAATAG
+GACCATTATTTTTTCTGTCAAATAATACAATCAAACTTTCTTTATTTATT
+TTTTTTTTACTTTCTTTCAGTAAATATTATTATCATTTTAGTGGTTCTTT
+TATTTTATTTGCTGGTCAGAAAAGCTGATTTTTTCAATTAGCGAAAATCC
+ATCAAGTCATATTTCTATAGACTCTTTACTACATACGTTGATGACTTTCG
+TGATTTTCTCCTTATCCGGTTCATCCATTCCAGCTTTATTATTGTTGAAA
+GTAAATAAGCATTGTTTCCCGAAAAAGAGCCGGATTTTGAAATTCGCGGA
+GAAAAAGTTGAAAATTGAAAAATCCAAACGATGCTCCGATGTTCCGTCCG
+AAATGTGTGTTTTACCGTGACGGTGTTTGCAGACAGCTTGAAAAAACATT
+TATTTTTTTATTTTAATTTTATTAATTTATTATTTATTTTAGAATGTTCT
+ATATTTTAAAATGTGAATTTGTTTCAGGGTACTCGGAATGTTTGTCTTAA
+ACCGTTCAAGCGGGCTCATTCATCGATCTGTACCTTTATTAGCTCAAGTA
+TCCACGCCTACGACTTCCACAACAAAATTAGGTTAATAATTCTCCATTTG
+GTGATAAACCAATTCTTTTCTGCTTTTTTAAAACATTATGTTACAGCTCA
+ACTTCACACAACGCATGCACTAAGCAAAGAAGATTATTATAAGACTTTGG
+GTGTCGACAAAAAATCTGATGCAAAAGCAATCAAAAAGGCTTATTTCCAG
+GTAATATAAGTTTTTATCGAATACTTTGTAAGTATAAATACGTTATTTCA
+GCTTGCCAAGAAATACCATCCAGATGTAAACAAAACAAAAGAAGCGCAGA
+CGAAATTTCAAGAGATTTCTGAAGCATATGAGGTATTTTCAACAAACAAT
+AGAGCAGGCTCGAATCAAAAATATTAAGGTACTTTCCGATGACACAAAAC
+GTCAAGAATATGATGCATACGGAAGCGGAGGTGGCCCAGCTGGTGGAAGA
+GGTGGTGCTGGAGGTTTCCACCACCATGGAAATGTTGATGTTAACGAAAT
+TTTCAGAAGAGCATTTGGTGGAGGGGGTGGAATGGTGAGTTCTCCTTATG
+AATTCTTCTGAATATTATATTAATTATATAATTTTTATTGTAATTAATAA
+AAACTACAGTTTTATTTATTTTTTCGCTGATTCCAGGGTGGCTTTAATTT
+TGATAATTTTGCCCAAAGTGCTTTCGGACATTCTGCTGCTCAGGAAATGG
+TTATGGATATTTCGTTCGAAGAAGCTGTCCGAGGAGCCACCAAAAATGTT
+TCTGTAAACGTAGTTGAAGATTGTCTGAAATGTCACGGAACTCAAGTTGA
+ACCAGGTCACAAAAAGACGTCGTGTCCGTATTGTAACGGAACTGGAGCAG
+TTTCTCAACGTCTTCAGGGTGGTTTCTTCTATCAAACAACTTGTAATCGA
+TGCAGAGGAAGTGGACATTATAATAAGGTAGAGTTATTGATTTTTCTTTT
+ATTGTAGCTTTTAATTTTTTCTTCAGAATCCTTGTCAAGAATGTGAAGGT
+GAAGGTCAAACCGTTCAACGACGTCAAGTATCATTCAATGTGCCAGCTGG
+AACTAATAATGGAGATAGTTTGAAGTTCCAAGTGGGGAAAAATCAATTAT
+TTGTTCGTTTCAACGTTGCACCATCTTTGAAATTCCGACGTGAGAAAGAT
+GATATTCACTGTGACGTAGATATTTCTCTGGCTCAAGCTGTTCTTGGTGG
+TACTGTAAAGGTTCCTGGAATTAATGGAGATACATATGTTCATATTCCGG
+CAGGAACTGGCAGTCACACTAAAATGAGGTAATAAATCTCCAAAAATTGG
+AACTTAAATATTCATTAAACAATTTTCAGATTAACAGGAAAAGGAGTAAA
+ACGATTGCATTCTTACGGAAATGGAGATCAATATATGCATATTAAAGTAA
+CGGTTCCGAAATATTTGACAGCCGAACAGAAACAAATTATGTTGGCTTGG
+GCTGCGACGGAACAGCTGAAAGATGGAACCATCAAAGGATTGGAGAAAAA
+TCAGAAAACCGAGGAGAAGGAGACGAAGAAAAATGAGGAAAAGAAGTCTG
+AAGGTGAAAAAATATGATTTCAATTTGAAACAAAGGTTTTATCAAAAAGT
+TGTCTTTAAAAAATCGAGAAATTACCAAAAAAAATTCATTAATTTTTTTT
+TTTTAAACCGACATTATTGGTTGTAAAGATTCAAAAAGTTTGTAAAATTT
+TAAAGTTGTTTGAAAAATACCTGAAAGTCTTGTTTTTTTTTTTGCATTCT
+GATGCACTTGTAATCTCAATTTTTCCCCAAAACTGATTTTTGATTCTTTT
+CAATCCAAAATTACTAATTTATAGGTGCATCAGAATCACAAAAACGGAGA
+AGTGAGCCAGTAGCTGAGAATGCAGAAACTATTGACGAAAATCAAGAAAA
+CGAGGGATTTTTCGAAAAAATTAAACGAAAAATTTTCGGGTAAATATATA
+AATTTCTAAACAAAAATTAAATATTTTTGTTTCATTTGTATTAATTGAAA
+TTTTCCAGATAAGTCCGAGGAGAAGTCCGAGTCAAAAGAAGAGCCAAAAA
+ACGAAGAATCTAGTGAAACCCCCGAGAAAAAAGCTGCAGAATCCTAATAT
+TTGTCGCAATTTATCGATTACTGTCCCAATCTTTCCAGTTTTGTTCCCTT
+GAAATTTGTTTTGTCTCATTTGTAGTTCTATTAGAGTGATTATAGTGTCT
+TTTTTGTTACACTTGTTTTTTTTTTCTATTTTCAATTAAACCGAAACAAA
+TTTATCAAATTTTATTCAGAAAGAGATAACACAACTAGCAATGATATGAA
+GAGTTTTATGGATGAAACTGGATTTTTTTAGAAAATGGTCTGTAACTTGG
+CTGAACATGAAAATATCAAAAACCTCAAAATTGATAAAATGTGGTAAAAT
+GTTTTTCAGTTTTACTACACAACAAAGATTTTTTTATGAAATTAGATGGA
+TGTTGAGTTATGACTGGTAGAACAGAAAAGTTTTCAAAAATTTTTGTGGA
+TTTTGGTAAAATGGCTTTGACTCAATGTAACGCAACGAATAATTGGTATT
+TAAAAATGACAAAGATTTTAAAAGAAAGAAAAAACATTTCTGATCATTAT
+GTCAGTTGAACATTTGTTTCCTAGGCATTCATGTTTCAAGATACGCCAGT
+TTGAAGATACGCAGTTTAGTGAGTTTAGGAAGTTATATTCTCATTACAAG
+CACAGGTACATGAGAAAACAGCAGTCAAAGAAGGGCGGTATTTTTTAATT
+TGGAATTATATTTTGCTCCTTATAATATTGGGAACACATCTGTGCTGCTA
+AATTATTGTTTTGTTAATTTAAACCGAAACAAATTAATCAAAATTTATTG
+TAAAATAAAAATACAACTAGCAAAATATTTTATAGGACAAAATATGAAAA
+ACGGAATGTCGTGTGAAGATGGAATTGAAAAGATATGAAATCATTGTGAT
+CTGTTCAGGCAAACTTTATAAAAAGCAAGGTTTTCGGGATAGTTTGAAAG
+AGCAGATCACCTGGATGTGAAAATACGGTGACATTTTTTTGGAAAAGGGA
+AAGAAAATGAAAAAAAATCGATAATTTATAGAAATTTTAGCCCGTTTTTA
+ATTAGGGAAAGGGCGGTGAGTTAAGGATGTGAAATAATTGAAATTTCAAA
+ATGGAAAAGTGGTTTTTTTTGCACAGAATTTTTCATTTTTCATCTTGAAG
+GTTATATTAAACACGCGATGACTGTATTTAGAACCCATTAAAATAATGGA
+GAAAAATGTCTCAAAACTGAAATACTGATTTGAGAAAACCATTTTCCCTA
+TTTGAAAACTAAAAAAGATGACAAAATATAAAAATGGAAAATCTATTTGA
+ATGCACGATTGAGAGAATATCTTGAATGACAAAATCTACAACTTTGCATA
+TCAATTGCAGACGATGACGTGGAAATGGTAGCAGCATCGGCAGTTTGATC
+AATATATCGAATACATCGGATATCAGTTGGTATGAATGGTATGATGTGTT
+TGGAAACATAGAGATTCTCCACTATAAAAGCTTCTCGGGACATGTTACGA
+GCTCGCTTTTGCATTAAATTTGCGTAGAGTTCTGATACAAGGACTACCTG
+GAAATATTTCAATTTTCCGTTGATCAACATAAAAAAGCAAAAAAAAATGC
+TTTTCAAAAAAGGCAAAAGTTTTTTAAAAGTTTCAACTATATGCATATTT
+TTGACCACAAAACCAAAACAAAACAAACTCAATAATATAAGTAAAGAAAA
+CATTATGGAAATCATTTTCTCGCAAGGTCTTGTAAAACTAAATCGCACTT
+GAAACTGACTATTTATATATATGAGAAAAATGAAGGAGTCCTCCAAAAAT
+GATGCAACTCAAAAACGAAACATCAAAACGTATTTTTCAACATTTCGCAT
+TTCGCATTAGAGACATTTCGCATAGAACGGATTTATGTGGAAATTTATGG
+ACGTTTTCGTCCTTTTTAGATACATGAGCACATGTTCTCCTGTTTTATTT
+AGAGAGATGACTTGCTTTCAAAATTAAAAAAAAAAACTGCTTATACATAC
+CTTTCCTCCTACAACCGCCAATGCAGATCTAGCGTCTTGAATTTTTCTTC
+CGAAATAATGAATCTTTCGAATATACTGTACTCCTACCAAATCAATGCAC
+ATTGTAGTTATTGCAAGACCTAAAAATATTTTGAATTTTTGTTTTTTTTT
+CATTGAAAATTTACCTAAAATGATATAGAGCAATATGATATACATGTATC
+CGTCCCTTCTGGGCATCAAGTCGCCAAACCCGACCTAAAAATATTAATTT
+CAAAGAGTTCAACAAACTGGAACAAATTACAGTAGTCATTGTAATGAAGG
+ACCAGTAGAATGAAGTGAAGAAAGACCACGGCTCTAATTTTGACATTAGG
+ACACCGCCAAACGCTGTATATACTATCAGAATAGCTAATACCAGGAATGC
+AGGAATTCTGGAAAGACAAAAATTGAGATGAGTGAATTAAGTTTTGAAAG
+GTAATTTTCAAAATCCATTAAAAATGTATTAAAAATATTTTACAGTTTTC
+CAACGACCAAAAAATCTGTCGAACATATACAAAAAACCAAAGCCAGCTTA
+CAATGGAACCCCTAGTTTTTGTGATTGATCGATTGTTTCATAAATGTGTT
+TTATAACATTACGAACAAAAAACGCTTCTTGACTGGCAAAAACGTTTACC
+TTTTCTCCTCGATATTCATATCATGCCCCATTCCATGACTGTGACAGTGC
+TCACAAACGTGCTCTCTCCGTTCTTTTCGATGTCGTGACAATATGAGATA
+TTTTAATTTCAAATAGTTTCCATACAACCAAACAAGATGTTCAGATAGGA
+ATTTACCTGAAAATTATTAAAATTATAATACATTTTCTACATTTTCCCTT
+TAAAAACAAATTTTAGATGCGATTAGCTGATCGCAGTAGCTATCAGATGT
+AACTGATGTTTTTTTAAAAACTTCACGTACTACAGATTTTCTAGTAAAAG
+CATATAAGTGCCTGCCCACTTACCCAAGTCAGCGATGGTAACCAGTGTTA
+GAGGTATTCCAAGCAAGGAGAACAATATACACCATATCCGTCCAATGTTT
+GTCACTGGAACTGGATTACCGTATCCGATGGTAGTGACGACGGTTACGGC
+AAAGAAAATGGACGATGAAAATGTCCATGTCTCCGTTGCTGCGTTCTTTT
+TTACCTGAAAATAAATTAAATTATTTTTGAGGTATTTTGAGGTAGTATTA
+TTGTATTAAAAGTTTGAATAATTTTGGTTGAATTTGGAATAGGTTGAAAT
+CAAACTTTTCAAGTAAAAAACAAAGTTTCAATAGAAACAGTTTGAGAGAA
+ATGATAAATAGCTGACCGGAAATGAGTACGAAAATCTACTTTTTAAACTT
+TGAGTATGCTCTGAAATATTTTCCTGTTATTTCCTTTTTCCATATTCTGG
+CTTTCAATTATCTTTAAAAAATTTTAAAGACACATCTTGGTTAAGTGTTT
+GGTGAAACTATAAATCTAAAACTATTTTTAAAGGAAAATCCTTGTCCCTT
+TGGATTAAAAAGAACAAGAATAATTTTGAAATGTTTAATTACAGACACAG
+ACAATTGCTCAGTTAGCGCATAAAAAAATAAGCAGACAATGAACCAACAG
+AACAAAAAACTTGAAAGGGTCTCTCTATCTGACAAGTTAGAGTTTTGTCA
+TCTCCCGCGGGAACAGCTGAGCTTTCTCCACTTGTTTTTGTCTAATCTCT
+CCACATTTTTCATGATCTATTGTTGTTTCTATCTTTTGATAGTCACAAGG
+GACCTCTTGTGTTTTCCGTTTCTATTTCACACCGCCAAACAGACTCAAAG
+AATGGAAGGTTTTGTGGAAAAATAGGAAAAAGATGAATTGGTGAGGATTA
+TCAAGGATGGGGGAAAAGAGGTCGATAAGGAAATAGTTGGGTTAGAGAAG
+AACAAATAATAGTCCGGGTAGTTTGGATGGTTCAGATGTTACTTCTATAT
+TGATAAATTATAAGTTGTGTCGATGCAAAATGTTAATTTAAATAGCCGAT
+CGTAGTTTGAAGCAATCAGTTTACTGGTCAATTTCCGGCACATTTCGGCC
+AATTTTTGCCAAAATATTATATAAGTTTAGTTAGAAAGTTTTCAAAGCTG
+GAAATAAATTCGGCAAGACTTGGCCTAGATTTCCAAGTTTAGCTAAGCTT
+TGATTAAACTTCTGTCAATTTTTCATGAAAACTGTTCGTATTTTTTTATA
+GGGTCGAAATCGGGATGCCTGGAGTTGTGCCCGGATTGAGAAAAAAATTT
+GCAAATAGCCATCTCAATTACTCAATTACAAATTGCTTGCAATACATTTT
+CCGTACCTTCTGGTCGTCACATGCAATCTTTACAACAAAAAGTCCTGTCA
+AACTCACCTCGTTACTCGTCAAGAAATACTTCTCAAATGCGACAAACAGC
+TGATCGGACATATTGTGCATGTGCCGTTCGGCTAGTGACTCCCATTCGTA
+TCGTTCTGCAGACAATTGTGTTCAGGAAATTTTGTGGATTTCCATTTTTT
+GCCAGTTTGGTCGAATTATGTGTTGTAGGTATTGTCAAACAAGTTTCGTA
+AATTTGGCAATGTGCCAAAACTTTCAAAAAAAAAAAACAACGCTTTTAAA
+GTGTTTTAAAATACTTGGTCAATCTGAATTAATATAATTGCATGTAAATC
+CCCACTACTGATATTAAAAAGTTATGCCAATCTAACTTACTTGTCTCATT
+TCCAGCAGCCAAACGAATTAAGTCGTCAACAAACTCATTTTGACGAGTGT
+AGATCAGTTTAAGCTGAAAACTATTATTATTTTGAAAATTTCATATAATA
+TTTCGAAATATTCATAGAAAGAAAACAATTGTGTCCACAAAAATGCTGTT
+GTAAATATATAATTAGGTGCACTCATGTGCTGCCAGGTTGTTCTTTGTTG
+AAAAATTCGATTTCAGGATGCCATAAAGTAAATGGGAAAATATAATGGAA
+TCTAACGCGACATTGTTTAAAATACTTTGGCCGCTTGTGACGCCACACTG
+TTAAGTTTTAAAAATATATAAATTGATCCAAAAAAATTGAAACTAACTAT
+AAGCTTGACGAATAAAATCTAAGAGCCTAATATAAAAAAGAAGCTTTTTC
+TCATGCTAGGTACTAAAAAAGGCGCCCGAAAAGCACCTGGCCACCGCAGC
+CTTTTTTCCAGAAAATCGGAAGTCGTTCGCAAAGAAAATGGAAATGCTTG
+AGCCAACTGAGCCCATCTGCCACGTCAATGAAATAGGCAGATGGCTGAAT
+CGAACGGAAAAGAAGAAGGATGTGACGAGTGAATGAATGGCTTTTTGCGT
+TGAAAAAGTACCACTTTTGGTAGAATAAGATGGGCGAGTGGGAGTGAAGG
+AGTAGAAATAATAGAAATTGAAAATTGGAAACTTTTTCATAATTTTAACT
+AGATTAATTTTAGATGTCAGAGATAAATCAAAATGTGCTTCAAAATAAAA
+TAGTCTGAAATAGTCTTAATCCTTTTTATGCAAAATAAAAATTCGAACTT
+CCCCGAAATTCAAGTGGCATAATTGTTGCAATTTACACAGTAGTTTTGTG
+ATTTTTGCGCCAAAAGACAAATTATTATCAAGTGTGAAAAAAGTGTGCGC
+CTTTGAAGAGTACTGTAGTTCTAAACTCTTGTTGCTGCAGGGTTTTTCAA
+AGTTTTTGTCATTTTTTTAATGTTTATCTTTATATTTTTAATTCATACAT
+GTATTTTAAAAATATATTTTTAACAAAAACTGTGAAAAATCTAAATAGAT
+TTCGCAGCAATGAGAGTTTGCAGTTACAGTTATTATATATCTTTAAAGGC
+ACACACCTTTTTGAAATTAACAAACAATATCGAGTCGAGACCGCGTACCG
+TATTAATATCGCAAAACTTAGAGTTTTATTTGTTTTTATCTTGATGAAAG
+GCTTTTCAGGAGAACGTTTTTTTTTCAAGAAGAATTATCACCTCTCTCAC
+GAATTATCAACTCGTTCTCATTTTATTTCATTTTTAAGTGTACATACACA
+TCGCTGTTAGTTACCATCGCACGGATGGCCGAGTGGTCTAAGGCGCCAGA
+CTCAAGCGAAATGCTTGCCTCATGCTCGAGGTCGACTGGGTGTTCTGGTA
+CTCGTATGGGTGCGTGGGTTCGAATCCCACTTCGTGCAGAATTTTTTATG
+TTTTCAACCTTGACCAAAAGTCATATTCATCCAATTCGGTACCCTATTTC
+TACGTTATCTTGTTCCTCAAACGATGGCCTTATGTTTTGATCTTCAACAC
+TGCATAAGGAAATGTATACCAAAGACGAAGGTCGTTTTGATTTTTCAGTA
+ACTGGCAGCAATGATCCTTAAATCAGACTCCCACGCCCCTTCCGTTGAAA
+ATAGGGCTTCGATCGCCAAACTAATCTTATAAACACTAGAAAAGTTTTTG
+TTAAAAATCCGTATAAAAAGGGAATAATGTGATGAAAAAAGGCATCAAAT
+TTCAAATTTGAACATTTCAAGCTTAACTCGAACTTCAGCTTTCTCGCGAA
+AAAATGAGTCAAATCTTCCAAATTCTTGTGATCTTCGCCATTTTGTCAGC
+ATTGCAAGTGAATGGGTAGGTGAAGTACAGTACTTTATGGCATCAAATGA
+AATATACTCAGATTCCTCTTTCCAACTTATTCGTCAGGATATGACTACGA
+TTGTTATGGATACGGTAACAATGGTTACGGTAATGGTGGATACGGCTATG
+GAAATGGTGGCGGATACTATGGAGGATACAATGGATACTAAATAAAATAA
+ATGAATACTTTTTGACGGATTTTTCATTGAAAATTTATTTAATAAATGTT
+AAGCATTCATAAGTCTTGATGTAGCCTACCCTGAAGTATGATTTCGGACG
+GAATTATTAGGTGTAGGTCGTTTCCTACGTTTGCCTTATATGCAGGCAGG
+CACGCCTTCGCGGAGATCAGGGGTGTATTTTTGCTATCGGGCAATCAAAT
+GAAATATAGATTTGAAAAATTTTGTATTTTTTTTTTCTCTAAATGTTTTC
+AATTTTCAAGCTCAAAACATTTCAAGCCTAGAAGGAATTGTTTCAAATTT
+CTTCTCTCAAGTTGTGGAACTATTTCCAATATAATATATTTATTCCAAAT
+TACTCCCATGTGAACTATAGAACACGTATTGTCTCATCATTTCACTTTTA
+TAGTTTCTGTATTACAACACTTGAATGAATGCTTGGTGTAAACAATTTAT
+CAATGTGATAAACAATTCGATTTGACGAATTTTTCCGAATTCTCAGGATG
+ACCGAGTTTCGATGGTCAGTGGGAGTAAATGAATTGGGCAAATTGGTAAT
+GGAAATCTAGTTTTTATGGTGAGTCATGGCAAAGAAATCAAACATTTAAA
+AATTACAAGTGATAAACCATGAGTAAACTTAATCAGGCAAGCTGGCGTTA
+TCAAGTTGTTCAGTTGTTATAATAAAAATTACAAAAAAGATTTTCAAACA
+ATGTAGATTTTTTCCACTATCAATATTCGGTAACTCAAAATAAGTCTCCG
+TAGCATAGGACCTGGCAGCCTACACCTACATCTACATCTACATCTACACC
+TACCCACACTACAAGTACACCTAAATTAATGGTTCAAATGAGTCAAACTA
+ACCTGTTGTTCCTTCATCATTTGCTCGTGCGGCTGCTCAACACTATAAAA
+TATCAATGCTCCAATTACTGTATATGTACACGTTAGAAGTACAAGTGCAA
+CATGAGGTAGGACGAGTTTAGCAAACTGAAATAGGAAAATCACTTCAATT
+AAAATATTAGAATAAATACTAAGTTTTCAATTTTTAATTAATTAATTTCA
+ACGCGTTTGAATAATTTTGTTAAACTGTCGAGGAAAAAAATCTCATAGTC
+AGCGATCGAATTCTCACGAGTTCTGCCAATTTTTCCTTTTTTTTTAGATT
+CTTGTTTCCAATAGATTACCTTCCTGATTCCAGTCTCCTCTTCTTCTTCA
+TCTTCATCTTTACTTTCATCATCACTTTCATCGTCGATATCTTCATGGCC
+ACTCTGAAAAGTTGTATTAACTTTTTAAAAATTCAACCAAAAATAAAAAT
+AAACAACTGTGTGAATCAAATGAAAAACTTTTAGTTAAAATTCTATAACA
+TTGAAAATTGTATGAAACTAACAATAAAATCACACAGTTGACTATTTTCT
+TCAACGATCCATTTTTGCTAATGATTATAAAATGGTTAGCATAAAAATCC
+TTGTAAAATCAATAAAAACACACAAAATGGGTATATGGGAAAGGGGAATA
+TAAATGAAAAATTCCATGCTTCTAATTCCAAAACCTACTTAATAAACTCA
+CAATTATGGCTGAAATCAAGCTGATTTCTAGCTCAACTTCCTCATTTTCA
+ATGAAAATTTTTGCAGATTTTTTCGATTTTTTTATTTTCCGATTTGCGTA
+CGGACATTGATGAGGGTTATCTGGTGCTTCCTGTTTTACAAGAGTTTTAC
+AAAATAGGGAAAAGAGCAAAAGGCACAGTAAATCTTGTAAATTTAGAATT
+AATGAAAACAAACCTTATCACAACTGTGAATTAAATGACTATCTTCATAA
+TATTCAGCTCTTCCAAGTCCAGCTCTTGTTACTTCTTCACCGAATAAAGC
+TTCCTGAAAATAAAGGGAAAAGGGCATGCAAACGTTTTTGGAAAATCATG
+CAGTTTTTATTTTTATTTTCTAAGATGCATTTTATTGTCCACGGTGTTAA
+CACCTGGTAACTCTATCTATATATGTTTTTTTTTGAAATTTCTTATACCT
+TTAGCTCTGGTATACCTAATTTTTTTAAATATTAATTTTAAAAATTACAT
+GCATTACTAACAGAGATAATTATTCTGATCATTAAAATTTTGTGATTGCT
+CTGGTCCTTGTAGATAAAAATAGACAAAATAATTACCCTCCTCAAAACTC
+TCAACTCTTCATCTGTTGCCACGTCATCTCCGTAAATCAAGTTCTCAAAA
+ATTTTAATATTATGATCAATTGAGCCATTATTATTTTCATAATGATCTGG
+TTTTGTATAGCCACGTTTTTCATTTATAAAAAACTTTGCGATTCCAAAAA
+ATTCCATTATGAAGAATTTGGAGACCGTGCTGAAAACATCCATCAAAATT
+GAGTTAAAGAAAATCGAAATAATTAAATGAAATTGAGTTGAACGTAGGAT
+ATTTATTAATTTGTTTTAAAATCAGTTTAAAACCATTTTTGACGAATCTC
+AAAGCATTCAAAAATAAATAACAGAACATGGGAAAAATTGTATGAGTTTA
+TATAATACGTTTTCTCATGGTACTATTGATTGATCAGTGACAGAGTTTTC
+GATTCAAATTATTATGTCGCCTTGATCAATGAACTGAATTTTCTGAAATC
+GTATGTCATACTATTTACTAAAACTTCACAAGTCATAAAAATCAAAATAT
+CAAAAAAAAAGGATCTAGAGAACTTTCAATTTTTCTCCGTTTCAAAAGTG
+TTTGCCAAAAACCGAAATGGGAGTACATTTCTGAAGATTCCTTTTTTCTT
+TTTTGTTCAAAAAAAAGTTGTTAAGCTGGAAAAAAACTTTGGTTTGAAGA
+GATGGAAGTTGTCTTGGACACACTCACATTTTTGATGGACAGCCTATCAG
+CGAACCACTTTTGGATTCTTGGCGAGAAATTTTTGAATTTTCGAGTCAAT
+TTTCATGTCTAACTTGAGTATATTTATGACAGATATCACATTTTTCGAAA
+ACAACAAAACAGAAATAAAAATTTATGAAAAACAGATTTTTTTCCGGATT
+TCAAAATTGTAAACTAGAATTTAGATTTTTTCTATTAGTAATGCATACAA
+CTTTTTGGAAGGAAAAATACTAGAATTTTAGTAAAATTTGTTTTTTTTTA
+ATTTTCTAATTTCTACAATTTTCCAAAACCATGCAAGAATCCATTCAATG
+TCACCCAAAAAAGCAAAAGTCAAACAAGAAAAATCAATTAAAAAAAAGTT
+GAACCCTTTCAATTTATACACTCACCCTTCTCTGCCGTCTATGAAATCCT
+TCTGGAATTTCAGTGACTCGATCATCCATCTCATGCCGTTCAAGTTCTTC
+ATAGCTGTCATATTCAACTCCTACGTGGTGGTATGTTGAAGCTGCAACAG
+AAAAATTGAACATCAAGTTATTTCTTACAGCTTGAACCTTCAGCTCGCGC
+AGATTAAAAATTGGTAACTCCGTTGCAAAAAAGATGGAGTTGCGTTTTTG
+GGAAGTTTTCAAGATTTCTTACTAAGAAGTTTGGTACTTCGGAGTTATGT
+TGAGTATAATAGGGCAACTACCCAAGTTTATTCTACCTTTAACAATCCTA
+ACACTACTTACCGTAATCATCGTTATTACGATGAAGCAATGCTTCATGTG
+GATTATCACCTTCCTCTTCCATAAGTAGACTGCCACCATCACCACTAGAG
+TCAACTCGTTGATATCCACGAGATGATGAAGTCATCGCTGATGACGTGGC
+ATCTGAAAACTCAATTAATTGATGTTAAATTAATTGTATTATAATATTAA
+GTTCAACTTGAATTTTCTGAATGTATGGAAATTGAGCTTTTTTTTTAGCA
+AATCGCCATTTTGAAAACTCTCATTTTCAAATAGGGTCTAAAAGAGACAA
+AAAGGCAATACCTGTTCATAAGACACTGTTTGAAATTTTCAGTGAAAATT
+TTGGCAATATGCCAAAATTGCAAAAAACTACAAGTTATGATATAAGATGC
+TACGAGAAAAAATAAAAATGTAAATTTCAATCTACATCTTCTAAAAATTG
+TAAGAACATCATGCAAAACCTGCAACAAAACCTTGAAAAATTGAAAGAAA
+AAAGAAAGGTGAGGTAATCTGAGTCAAGGTGGAATGATGGAGGTTGGTGG
+GAAGAGGAAGGAAATTCAAAACCGCATAGACACCAAATATTGCAATGTTT
+GACAGAGGGCGACGAGGAGAGGAAAAAAACGAGATGAGCTCACGGGCGGA
+AAAAAGTTTTTTTGGAAGCGCTAAACTGATTAGTCAGTGGCGGTGGAGGA
+AGACCATTGGTATTGGATGGATAGCCCCCAATTTCGATGATTGACTTTTA
+CACATATACACACCAAGCTTTTGTTTAGAAAAAAGAAACAAAGAATTGTG
+TGTGTTGTAGGATGCCATTTTGAGGCGTGTGATTTGATAAATGAAGACTT
+CAACACCACTACTCCCTTGAGTCCAGATGAATTGAAGAACACGAAAAAAC
+GATTTATAAACAGATGGTTTCGTGTGGTTTCTGTGTTTTAAAAAGGCTGA
+CCAAAAAACTTCTGTTTTACAGGACGATGTGAGGGCTCTTCCAAGCTCGT
+TCTTTCCTCGCGCCTTACCGCAACTACCCATTAGTTTATCTGTGAGTTTA
+TTGAAATACAGTAACCTAGCTTCACCGTATTTCCTCTAATAGTATTTCAC
+CACACCACTTTACTTTAAAAGGTTATATCTTGGTGAACTTCAAAGATATG
+AAAAATTATAAAGTATGAATCGACTAAAAAACGAATATTCTTCCAACTTG
+AAATTTTTGAAAAGAACAAACGACAGCTGAGATATAAGTTGTTAAAGTTG
+AACAATGGGGTCCAACACTAGTAGAGGATCATATTACTCTTTGTAAAACT
+TTTTCGAATAGTGGAAAACTTAGTCGTAAATACACAAAATTAGACTCTAG
+TGACTCATAAATTTCGATCAAAATCTTTGAAATGTAGAATTTTTTGCCAG
+CAAGTTCTGTGAGCCACAACAATCAAAGAAGAAACCATGGAAAATGTTGA
+ATCGGTCAAAGGAAATCGCGGAAAAAGTAGTGGAAAAGGGGCAAAAAGTG
+AAGAAGAACTAGGCAAGATTAATGAGCCGCCTTTTTGGCTCTGAAGAGCC
+ATGTTTCCCTTGTGAGCATCATTTCTTCCGCGGCGCAAAGAATACGGAAG
+AATTGGAACAAACTTTTGATATTTGTTAAATATTTGCCCTTTTGGAAAAA
+ATCGTTGTGGTTGTGAAGGAAAAAACTACAGACAAAACATTTGTAAAAGT
+CGAAAATTGCTTGAAAATTTGCGAAATCGGTGAAACAATCAGAATTTCTG
+GCTTTGCCACCAATACCTAACGAGACCCTGCGTTTAGGGGCGGAGCATTT
+TATTAAGCCATGGAGCGCGATTACACCTTGGAGTGCTTTTCGAAAAAAAC
+CAAATTCAAATAATTTTTTAAAAAATCGAGAAATTATAAGTTTTAATTTT
+AACTTTGCTCTATTGATATGGGTTATCTAGAAGCTAGACTCTCTATAAAA
+AATCGAATAAAAACTAACGCGAATAAATCTTGAAAAGGTCGGAGTGCTCC
+CGAGAAAAGTTTTTGTGCTCTTTTCGTCGTAAGACTTCAAAAAAAGAGGC
+ATTTGGTTTGAAAAATGGCTCTGATCTCTTCGGTTTTTGCCCTCTTTTTG
+TTTAGAATATTTCATCTGGAACAATATTTGGAATCACGGAAAGAAATTTG
+CAGATGGTATTGTTTATAACTTTTATATATTTATGGAAAATCACTCTTTT
+GAATAGATTGTTCCACAAAACCTCACAAAATACTGAAAAAAGGAGAAATG
+GAAGACAGATATACAACGATATAACTTTTTTTGAATATAGGTTAATAAAA
+AATATTTGTGGGGGAATATTTGAAGATATTGGCATATTGAAAAAAAAAAA
+GAAGAAAGCGGCTACCTTTGAGTTTTATGGACAATGGAAATGGGAAAAGA
+GAAGGAATTTCATAGGTAGCTAGGAAAAGGTTCTAGTATATGGAACTACG
+TTTTGGGTATTATAGAGTTCAATAATATGAAAATCAATTTAATGATGGCA
+CAGTTTACACCCTATTCCCGGCAGTCGAACACAAACTTGTGCAAAAAATA
+GTATGTCATTTTTGTTCTAATTTTTCCGAGCAGTCATGTCCGAGTGGTTA
+AGGAGATTGACTAGAAATCAATTGGGCTCTGCCCGCGTAGGTTCGAATCC
+TGCTGACTGCGTGTACTTTTTATTTTCTTTCAATTCATAGAGTAATGCAA
+ATTCTATTAAAATCGGATACAGTATGTTATGAAAAAAAAGTGTTCTTCTC
+GAAAGTATTTGGCCTCGCTTCTTCAGGCTGCTGGTTCTAGAGCAGCAGTC
+AACTCAATTGTTTTCCACTTTTCCTTCTCATTTTCATTTTTTCATCGCTC
+CTTTTTCGTTCCTCACACTCCTCTAATTTTCCCTTTTTTACTCATTTTTG
+GAAAAAAAAAAGAAAAGGAGGTCTTATTTTGTAATCCTTCGGAAATTCGA
+AAGCTTGAAGAAAAACTAATAATGATGGAACTGTGTGGATTATTGAACGA
+GAAAAAGTTTTAAAGGTGCATACAGTAATTTGTGTGTGGTCTCGCCGCGA
+TCTATGATATACCAGCAAATACGGGATTATTACTTCAATATTGATGGAGA
+ATGTACATAGAGGGAACGGGGTTGGGTATCGCTGTCAGAAAAATACTGAA
+AAACCAAAAAAAAAATCCAAAAAAATTGTTTTTCATGATTATAACCTAAA
+CTTCATGAGTAAAAGTATCAAACTATCTCATTCTGAACAAGTTGAAAACC
+TCGGGACCACCACACCAAGAAGTGAGAAGCGCCCTCTTTTTGGCCATTGT
+TCCCGGGGGACAGTTTTGCGATTTGACATAAAAATCGCGAGAATAGTGTG
+TGAGATGAAGAAACGCAGAGTAGTAGAAGTAGGGGTATACGATGTTAGGC
+AAAGAAAAGGAGGGAGCTGGAGAAATGTGTCTGAAGAGCACTGACTGACA
+AAAATGTGCAAAATGTCGGAAGGAGGATGGGTTTTCATGTTTTCGGTGTA
+AAACTGACATAAGAAAAACATAAGAATATTGGTAGAAACTGGTAGGGGTT
+GTTAGGTTTTTCAATCTTTGAGAAATTGACGAAAAGTTGAAGTCTTCCGA
+ACTTTTTTGTGAAATTTAGGAGAAAAGATCAATTGAACGTCGGATTGAGA
+ATTTAAAACTAGATAAGTTTCAACTCAAGCGACGTTTGAAAAGATATGAA
+GTTTTAAATGAAAAATAAACGAACATTTTAAACAGGCAAACAATGCCTGC
+CTACGTGCTTACAAGAAAATTGAAACTAACAAGTAGGGCTACCAAATCAG
+ACGTACGATTTCACTGGATTCCGGACGATCCCGCCCCTTGTTTGTTTCCA
+ATTTACAAGAATATAAATGGTTAGGTTTTCTACGTGCCTACACGTCAACT
+TCATGACTGCCTGCCTACTTGCCTACTATATGGATACCGTGGCGAGGTCT
+TCTGGTTTTGCAAGCGTGCAGGCAAGCAATAGTTTTTTTTCTGTATAAAC
+ATTCTGGAAAATTTAACTGACCGTGGTTTATCAAATACTTCAATACTTCA
+AAAATACAGTTTAAAACATAATTTTTCTTTTTTTTCAACTTCTAAACTAA
+CCTGTTGTAGATTCATCAATAGCCGGAATATCTGATTCTATTGAAGGTTC
+GAACGGCTTAGACGGCGTAGAAGCTGGAACTTTTCAGTCTATTTTCAGTT
+TAAAAAACTTTAACTAACCTTTTTTGAAAAGTCGTAAATATTTTGCTCCA
+GTTCCACGTGGCATGATAGCTGGGGAGCTTTTTCAATTTTGTTTCCGATT
+TCAAAACAATTTTCAAAAAACACTGGTAAAGTGCACTTCCTGCTCAATAT
+CAGCCAGACAGAAACCAGAAGAACACAACTATTTCTGTCTATTTTTCTGA
+GAGAAAAAGAGCATTTTGAGCAATTTTGAGCCAGAGAGTCCCAAAACACA
+TTTTAATTTGAAGGATCCTTGCTCCTGAGCCCCCAGTTTTACGGGTCAAG
+TTAGGCATAATTGAATATGAGGAGGCGCAGAAAAAAAGAGAAGAAAATAA
+ATGAAAATTAATTTTATGGAGCTAATTTTTGAAAAAGAAGCAGGAACTAA
+TGTTTTAATTGTTCGTAGTTTGACTTGATGTGTGGTGAATAGTGTTTTAG
+TGTTTCACTGATCCTTCAAAGTAGATGTTGCACCATGGTCGAGGGCGCTT
+TTCAACCGCTTTGCTCTGTGGACCACAGTTATTTGAACTTTTCTAATTAT
+TTTTTTTTGTTTTTTAGTTTAAATCAAAATAGTGTCACTATTTTACTTTT
+TTTTATATGAACAAAACACTGGGAGTCGGGGTTCCAAATTTTATGAATTC
+ATATCACATCACAGCGATTTTTGTATTTTCAAAAAAAAACAAAATTTCAG
+ATCATTCTCCGGAGGTGGACAGTAAATGTTCTCAAATCAATAAAATTTAA
+TTCGATTTGTGATCCCAACCATCAATATGCATAAATATTTCCCAGATCAT
+TCGAAGAAATCATTCGAAAATGCGTCTTCTTATTCTCGCCCTCGCCTCTT
+TTTCCGTTCTTGTGAGCTCTTTCATCGTAAGTTCTTCTTTTGACTAAAAC
+TGTGTGAAAACCGTGGAAATACGTGTTTATCAGAGTTAGTGACGAAATTT
+TACCTTTTAATGGTATGATGCCTCGTAAATTTAATCAAACCTCTGTAGAA
+AACTCGTGTCATGTCAAGCGATTCGAAATCGATTTCTGAATGTGAAACGG
+AAACCCGTGTCACTTTGATGTCCAAACGCAGGAATAATTCCTTTGAAATT
+CAGATTCGTACTCATGATCTGCAAAATGCACCAAAAGCAAGAAGATTCCT
+GAAAAGTTTTGATCAACCTGAAGTAGTTGATCTTACTAAGGATCCCACTA
+CGTTCCAGGAGTTTACCAAATTCTATGTCCAACTTCTAATCGACGTAATC
+CAAAAAAAAGACACCAGAAGCCTTCATGGCACACAATAATTACCTGGATC
+TTGAAATGTTGTTCAATGAATGTAATGCTCAACATTACGAAAATTTAGGT
+TGGTTTCTGTAATAATATTTCAAAGTCTTTTTTAATAAAATTTTCAGGAA
+TGTTCTTCAAATGGCTTCAACAATTTGCTGCTCATCACGAAGATCCAAAG
+ATCACAATTAAAGATTTCAAGGGAGATAAAACATCAGGAGAAATGATTCT
+TCATGTTAATACCTTCACTTTATTCAAGTACAGACAAGAATTTGACATGA
+AAGTTAGCGCTTTGAATGTGGGTTATTGAATCAATATTTTGAAGACAAAA
+CTAATTTTTCAGGACAATGGACTTGGGTGGAAGATTTTGTTTGTTGACCG
+CAGTCTTGGGTGTAATTGATTCATTTTTTGAAACCGAATAAACTAATTTG
+TTAAATTATTAAATTAGGCAATGGGACAGTCTGGAAGTTGCTAGAATCTA
+CCGATATTTATTAGATATTTATTACTTACTTGCTACTATGTTTCACAAAA
+CAATATCAGAGAAAAAAAATCAAAACTGAGAAAAAACGAAACAACTTACC
+GAACAATAGTTAGCATTGCTTTGTACAAAAAAAACTGTGAGGCTATTGGA
+GCACTCCTCTGATTGATCCGGTCGTGAGTATTGATTTTGTTTGTCAATTT
+GTCTAGGACGCAATTGATTCATCGTTTGAAAAAAAAGCTCGTTCATTCAA
+AATCATTGATTATTTATTCCATGCAGAAAACTGTTTTATAATTCTCGATA
+AAAATGTTATATTTTAAACTGTAAATATTTATTTTTCCACATGATATGGT
+CTAACCGTGGGCGTAATATTTTCGGTTTAGAACGGCTGAATCGAATCTTT
+TGGACTGCAAAGACGGATTGGATTTTGAAACAAACTACGGTGTTTTTGTG
+ACAGTATTAGTCAACGAATGGTAATTAGGCATATGTTTTTGGAACAACTC
+ATAATTTCTTGTTGGAAAACAAAAGTGGCAAAGTATAATTATTTAAAACT
+CTGACAAATCTTTTGTCTTTTTTCTCTGGTACTCCTGTTTTTAACAGTGT
+CCTTATTATGCTCCTATTACTCTTGTGTTGTGCACGTTCTTTTGAAATCT
+ATATTGCAGAGCGGGAATGAATTTAAATAAGAATAATTCAACTTGGTCAT
+TCAAACAATAAAACGCCTACCATTAATATATCCAAAATAAGTTCTTTATT
+TTTGCAAGGTATTCAAATATATCAATAACTCGAGCCTGAAGAAATCCACC
+GCTAGAACATAAAATTAACGATAAATATTAAGGCAAAATGTTTGGGCCGA
+ACCGGGAATCGAACCCGGGACCTCTCGCACCCGAAGCGAGAATCATACCT
+CTAGACCATCCGGCCACTGCCCGGCTGGAGAAAAATGGGGGACTTTGAGC
+GTTACAACATTCTCGAGGCCCTCTCGAGTCGAGGGGGACCGAGACGGAGA
+GTGCTAGGAAAACCAAGCATATTTGGTTTTTGAGTATATAGTCGTACGAT
+TGAGAGGAAGCAAAGATAGATTTATAGCTTTTAATTTATTTTTTCTAGGA
+TTTTACGTAACATTAATTTCAATACTGATTTCGAGATTTGTCTTTTGATA
+GATTTACAACATGGTTATCATCCGGTATACTATTGTATAAAAGATGGTCC
+TAAATTCTATGAGATTATTTTATATTCTCTCTCAACGAGATGCTTCTTCC
+AAAAATTTCAATTCTTCTATATATTCTCGTCGTTCTTCAAGAAACAGCGG
+CTGTCCCGGTGCTCTTTTTCGCTCCGGAAGAGCTGTTCCGTTTGAGCGTG
+TCGTTGGACAACAGGTGAATTTTTTATTTCATTTTGAGTGAGCCATTGTA
+ACATTGGATCATAAGAGTCACGTGGAAAGTAGAACAATCTCAACCCACAA
+GTTAAAGCCTAATATTATTCCAATGCCTCTAGTAAGATTTTTATAAAAAT
+AGAAACCTCGCCATATTAGCCAGACACGAGATTTTTACGATTTCTTCGTC
+AAATATACGGTACCCAATCTCGACACGTCAATTTTTCAATAAATGCAAAA
+AGATGTGCGCCTTCAATGAGTACTGTAACTTCAAACTTTTGTTGCTGCCG
+AATCGACTTAGTTTTGTGAAAATATATGTATTCATGTTTTAAACAACTCA
+GAATTAACCCAAAAATTTTAACAAAAACTTTTTTTTAAGCTATGAAAAAT
+CAATTTGAATTCGGCAGCAACAAATGTTTTAAATTACAGTATTTTTTAAA
+AGCTTACGCCATTTTGCATTCATTGAACATTTGTCGTGTCGAGGCCGGGT
+ATATTTTTGACAGAAAAAAAACAAAATTTCAGGTTCGTTGTTTTTTGTTG
+TCAAAATTATAATGTGTTTTAATATCATATCAAAAAATTAGTCATTTGAT
+TTTCGATAGATCAAGCTTCAGTAGAGGTTTCTAATCATTCGGAAATATAC
+ACAAAATCTTGAATTTACACTTCCGATCAGTTGGAGAATATCATTGATCT
+ATCAATAATGTTAGATTTTGTAGTTGATATTTTCACAAAACTCTCAAAAC
+TTTTTAACATAAAAAGTTGGCATGGTGCGTCTTATAATTTTTGAATAACT
+TATTAAATTTCTAAAATTAATATAGAGATTGGCTCCCACATGTCGAGAAG
+TTGAATTATTTGTTCCTTGTCTATTCACTTCTAACCGTGATTGTGTTATC
+GACAAAATATGTGTTCATGAGAAACCACTTCCCCTTTCATCGATTTCTGT
+GTCAAGCCCGAGTCCAAATACAAAACGGGAAGGTCATCCCGAGTTCATGA
+GCCAAATTGCGCCGCCTAGAAGAAATGTGAGAGTTGAGCACAGCATTCAA
+CAATTTCTAATCAGCTTTCAGGACTTTTTGCGATTCGGAAGAGCCGGAAT
+GGCTTCTGGAGTTGGTGGAGGATCGGAAGGAGGACCTGATGATGTGAAGA
+ATTCGTATATTCGGGTCAATGGGGAGCCAGAGATTGTTTATCAATAAAAT
+AATATGGATTCGATGCGTCCGATTATTTTTTTTTACTTGATATTACATTC
+TCGAAACTATTGTAATGTGTGGGGAATCGTTATAAATAAAATATCTTCTT
+GTTAAACAATTATTCCATGAAATATGAAGTTATAAAGATATAATCCAGAT
+ACGAAACTTTGAGATTTTCGTCCGAAAAGTACGGTAGTGGGTCTCGACAC
+GACAAATGTTAGTTGTGCGCCTTTGAAGATTACTATCATTTAATTTTTTG
+ATTAAATCGTTTTATTCTAAATGCTTAGTATTTACACAAATATATTTCAA
+TCGGAATTTTCAAAGTATTTTCCTAGAGGAAACTACTTTGAAAATTCAAA
+AATTCAGCAACAACGAGAGTTTGTAATTACGGTAATCTTCAAAGGCGCAC
+ACCTACTCGTATTTAACAAAAATTTGTCGTGTCAAGACCGGGTTCCGCTC
+TTTTTTGCAGTAGTACAGAGAATATTCCGAAAGAAGTTTGAAATTAAATT
+AATTTATTATACCGACAAATCATCAAATGTGATGTATTTCAATGAGTACA
+ATTTTTCGAAAGAAAAACAGATTGAGGATAAAACTTGAGTGATGAGATAA
+CCGTAATATGGAGAATTATATCAGTGTCAAGAAGGCACATTGTTCAGTTT
+CATATTTACAGATGTTTGGGATTAAATGAAGATTCGGTATGCATCGACGA
+TCAGAACAATGAACGAGTGAGTTGAAAGACCTGGAATGTTTAAAATTAAT
+TTTTAAATTAAAATTCAATTTTCTGCCAACCTTTTGTTGAATGATATCAG
+TTCTTGGAGAAGACCATCTTTCAATTGCTTCAAATTCACGACGTCTTTTC
+ACCAGTTGTAAGAAGGCGGTCAACGACCCGTCAACGTTTGCGTAGTGTGT
+GCGGCAGGAGAAGAGACTGCAAAACAGAGATATTTCATGAAGACTCAAAT
+GAACAGCGGAAAATGTGCCTCGATAGCTCAGTTGGGAGAGCGTACGACTG
+AAGATCGTAAGGTCACCAGTTCGATCCTGGTTCGGGGCAATTCTTTTTCG
+ATTTTTTGAAACTTACCAAATTCCATCATACGAGAGTCCTTGGTGCAGAA
+TTTCGTGAACCAAATCAAATTCTGCTTCTTGCCGGTTTAGAAGATCTGGT
+GCCAAAATGATGTCGAATTTTTTTCCGCCAAGGAACTTCATTGCCTCTTC
+AATTGTACCACATGAAACCTTGGTCTTGATCATTGGAATATTATTTCTCT
+TAAGTGTTGGACGACAGTAAAGCTCCAAACTAGTCTTATCCATTGTGTGC
+ATTGCAATTTCTTCTGCTCCATTTTCGAAAGCATATACTGATGGGAGTCC
+AGTTACGAATCCGATTTCCAAAACAGATTTTCCATCGAAAAAGTCAGTTT
+CCATCTCAACATTGACAATATTATCAATAGTGTGGCAAATTGTGTTGACA
+CCTTCCCAGTCATCATGATGATCTGAAAATAAGACATTTTCAAAATTAAA
+TCAAAAATTAAAAAAGCAATGCCCCGAACCAGGATCGAACTGGTGACCTT
+ACGATCTTCAGTCGTACGCTCTCCCAACTGAGCTATCGAGGCATGCCGAA
+ACTGACGTTTCTGATCAAACAGGAAAAATTTGAAATTGAACCGTACCTTG
+GTGACTATTTTTTCTCATTATAGGCAATTCCTCTGCCACATGATTTTTCG
+GGTTTGAATTTCTGGTTGCCACGTACTTGATGCAACGGCCGGAATCCAAA
+CTGAGTTCACAGTTGACTGGAGCAACGGAAGCAATTGTTGGGATGGTAAG
+GACCATTTTTGTGTGATGAAAGGATATGAGAAGAACGCTGAAACCGAGCC
+GGAGCTATTATTTATTTTGAAAAAAATGACCCGAAACTAAAGAGACAGGT
+GGTTCTTTGTAGTTTTAGATAGTAAATAAAGTAATGGGTAGGGGGCAAAA
+ACAAAGAAGATAAGATACGCTTTAGGATGGAGTGAATCTTGATCGCATGA
+CGTGAATGGCAGAAAGTTGAAATTTTGAAAAAAAAGGAAGGAAAAAGTTT
+GTACCGAAAACTAGAGAATTTCCAAAGGGTTTGTTTGCATTCGACCATTC
+AGTTGCTTTTAAAGATTGTCCCGCAAAAGAGAGAGGGGCGGAGTGAATGG
+AAAAGTCACGAGGGCGGGTTGTGTGCAGAACAACGGCAGGAAAATCATAA
+ACACGAACATAGAGAGAGCTATTGTACTTGGAAGAATCAAAGAACGAACT
+GGAGTACTGGAATTGAGTGTGGAATTTGTATGTCTAGGTCAGGAAAGTGA
+GATCTAAAGCTAAAATAAAAGTGAAAGTCCATCTGAGTTGCAGGAGAATA
+ATTGAGATATTAGTCGAGCTTGTTCTTCAACTCTAAAAACTAATTGAATA
+AGTTTAAAGTAAAATGGAGCTCTTGAGAAAAAGCGAAAATGCCATGCTGC
+TTTAATACCACCCTAACCCCCTTCTATTGACTCCGCCTACTTTTTGTCTT
+CGCTAGATGAAGTAGATGAAGACGCCGGAAGCAATTGGAGATGTTAGACG
+TTTAGAGATGATAGAATCTATTCATCCAAGTGAGAGATCAAACAAGACAC
+TGAAGAAGAAAAGAAGATTGGCGGTAAAAGGGATGATCTTCAAAGAACAG
+AGAGCTCCGACACTTTTTGTTTTTCATCTCTTTTTTCACTGGTTGGTGGT
+CAGCGAAGAGGAATAAGAAGAAGAATGATGGCAAGAAAAAGAGAACAGCT
+GATCGATTCTTGTTCCTGAATAGATCAATGACGTACCATGAAAGAGTGTG
+AGTAGGTGGATAGTTGATGAAATTGATGGCAGAGGGTAGATCATTGTAGA
+AAAGAACGATCAACTTGAAGTAAACACAAAGTAATACGATAGAGATGATT
+CCTTAGCAAAAATAGTACCGGTGTCTACTGAACAGATCACGATTAATCTT
+TTTTATAGAGAACTTCTGTTGCTTAGAGACATTGTTTTTTAGAAGAAGTT
+GAAATATCAATTGAGATTCTCGTCAACTTCCTGATGAACACAAATAACTG
+GGCATTCACCAAAGGGCACCGCGATCAGTTCAGGGTTTCACCTAGACCGG
+GTTATTCAAAACTTCGAAAAATTCGGATAACCTGTAATTTGTCGATTTTC
+CGAACTGGCCGATAATCAACGTGCCGAACGATAATCACCGCTCATTCCTG
+ATTGAATACACGAGAAGCTGCAAATTAAAATACCTAAATTTCGAGGTTTC
+CAGAGTTTAGCCAACATCTAAGCTTAGACAAAAAAAAGCCTTTGCGAGTG
+TTTCTGGAATGGATTATTTTCTCTCAGCTTCAGTAAAAGATCCTTGGTTA
+CTATTTCTTGACCATCTCACGTTTAACTCCCAAAAATCATCGAACACAAC
+TAATTTCTCAACAAACCTATTTACTTTATTTCGCCTTGCTTTGTTATTTA
+TTTCACTAAAAAACGAACCTCAATGATTCACGTGTGATCGGTGACCAATG
+AGGCTGGCTGGCACGTGTACCAGGCGAAAATTTTCAGTGAGAAACACAGA
+GAACAGTGTATTCGGTAAATAAAATTAAACTTATTAAACTTTTTTTGCTG
+CTGATTCACGTGAATAATACACCAATGTTTGAGGTGAGCAGACTGATGAT
+ATCATTATTAATAGCAAGCTAATTACTAATACATTTTTAGACGTAATTCA
+ATCTAACTATTTCTATAGGAATATTTTTTCAACTTGCGAAATAGTTCCAT
+AATAATAAAACAACTAGAATTGGGCCATCAAGTAGTTACAAAAACTGTGA
+CTGCCATAAAAGGATTCAGGTAGGTAGGTGGCGCCATGCGTTTCAATTGA
+ATATTACTGAGTCAACTTCACATCTACAAAAATCACAGCATGATCATATC
+TAGTAAAGAAATCATAATAACAGCTGAGAGTGTTCAGATTTGCATAAATG
+ATGACATCAACATCTGATCTAGTCCAAACAATCACACTTTCATTTCCTTC
+ATTCTATGAATAATCTTCTCTTTAAAAAGAACCTGTTCTTCAGGACCTCC
+ATCTATATTGTCGTCTTCTCGTATGTTCCCAAATGTTATGATAATACTAT
+CTTCTATGACATCTTTTGGTGTGGGTGCATAATGACGTGGCAACCGTACT
+CAGTGTGCACCAAACTACGAAAACAACGAACAAACAAAAGTGAGTGTTAT
+CTTATTATCGCATAACGAATTCTTGTCGAATGGCATGATATGGGGACCTG
+GAAATTTAATTTGAAAATCTATCCATCAACTGAAAGAAAAAAATGAATCA
+GAGGGATTTGCGAAATTTCAAAATCAAAGAATGACCACGTGTCTTATTCA
+ATCAAATCAGTGGACGTTTCTCATAGAATGCTGCAGAGTAGTTACGAAGG
+AAATGTCTCAGTTTCTACCGCCAGCCTATCACAGGGATGGGTCTCACCAC
+AACGGGCTTCGCAAAAATGGGTCTTGCAAGGATGGGTCCCGCAACAATCG
+GTTCCGTAACAATAAGTCTCGTAAAAATGGGTCTCACAGCGAAGAACCGC
+TTAAATCGTGTAACACGAGGCCCTTGCTTCCACGCCAAAATGCGGAAAAG
+AAGTACTCGGCATTCAGAGGCAACTTCCTGCCATTTTATGGCAACTTCCT
+GCCAAACTTTTGCACATTCCTGCCAACATTTAGATGTTGCTGAGCGTTTT
+TTCCCACTTGCTGCCACTACGTGGCGACTTCCTGCCAACAACTCGGCAAC
+TTCCTGCCAGCAATTTGGCAACTTATTTTAGTGGCACTAAATAAGTTGCC
+AAAGTGTGGCAGGAAGTTGTCTCTGAATGCCGAGTTGGCAGGCACGTAGG
+CATTTAAGGGGGAAGGTGCCTGTCTGCCCTAGAAGACTTACTAAATAACT
+ATGAAAAGCATTAACATTTAGCGGCCACGCATAACACTATAAACCATTTC
+AGTTTGCTTACAGAGAATAATCAAGAAAAGCGGAACGTTATCTTGAAACT
+ATTGAACTATCTCCATGTGATGCGTTTTCTAGCACTTGACTTAATTTATC
+ATTCCGTTTCTGTCGCTTGTGATAAGAAAATTCTCAAATTTAATCGCCAA
+TTTAATTTTTTCGCAGATGGTAATCTGTTTGGACTTTCGTTCCAGTTCGG
+TTCACGTGAAACTCATGTTCAAGTTTTTATTTTTTAATTTTCAGATGAGA
+GCTACGTAATCATATTTTTGTTTTGTTTGCATTGGTATGGTTCTTGATCT
+ACTCGTATGGGGGTAAAAACGTGTGTCTAGTTGACATCAGTCGAGTGATA
+AGATGGAGATGAATAGTTTGGGAAGAAGATGGGGATCGGAAAAAAGCTCA
+AGAAATGGGTTTCAACTTTTTGAAGTTTTAATTTGGCAGCGTGAACATTT
+GCAAGGTATATGAAACTTCAAGAAGGAGAAGTGTAGGAAACAATGTGGAG
+ACGCTGTTATAAATTACGTTTTGAAAAAGTCTCCGGTTTTCCGTCAAGCA
+ACTTAGATATACATATGTATACTGCTTCACTTTGAAAAATCAATATGTCG
+CAAAATAAAATAAAAATAAGCCGCGAAGAAAAATAAAAATAAGCCGCGTA
+GGCCCGTAACCGTCTTTCTACCTTACTTATCGGAGTACGCCTAACTCGTG
+CCTACGTGCCTACTGCCAAAACAAATTTGGCACGAGACAGGCCTTTTCAC
+ATGTAGTATTTTCGTAACATGGATGCGTTATCCGATATATGGAAACTTTA
+GAGCTTTTATTCATTTAAAGTCAGTTTCTAATTCTGATCAGTATCGCCTT
+GTGCTGAACAACGAATTGTTAATTACATAACCACATCTCGTACTTCTGAT
+CTATTGATACTTCTTTTTTGTTTTGTTTCCATTTTTAAAAAGTTGCTCGT
+GTTTTTTGTACTTTTCCGTTTTCATAGTCTTTACCATCAGTTGTCATGGA
+AATTGTTTTCAAAGTTTGTGGATTTCAACCCGGAAGTCTATCAATTGTTT
+GCCACTCTGTTTTGTCAATGTATTTCTAGGTGCACCTTGCAGACATGTAC
+TCTGCGACCGAACCTGTCACCTGACAAAGTACCGTAACTTATTGTTTTCA
+CAAACACTTAAAGATGCCTGACCTGGAACGACGATCACTATCATCAAACG
+GTAATGATCGAAATTAGTTGAAAACATGATTTGACCGCAGATCGAACTGA
+TGGCGCCAGGGAAACACCGATAGAAATGTTTTTCAAAAGTCACATGTGCT
+AAAAATAACTTTTATTTGGTCTTTCTTTTTCCTTTTGTCACATCAACCAT
+TACATGGGCGGTCAATATCTGTCTTCTTATCTATTCAGTCTCACGTTAAA
+TACACGTGTCAATTTATGTAAAAGTCGGGCGGTCCTGACTTTTGATGATC
+ATGACATGTTTTCGATCAGTCGGAAACTGGGGGGAAAAAGAGAAAGACAG
+AGACGTGTTTACCACTATGCAGCTGCAATTCGGTTTTCTCTCGAACATTC
+CATGACGAGAAGAGACGCAGAACATTCAATCAAGAGGGGTCTTTGAAGAT
+CATCGTGTGCTTCTTTTATGTGTGTTTGTGTACGTGTTTGTGTGTTACTA
+AAAGTTGACTGAGGGACGGGAGACAGAGAGAGCTCAATGAGCAATGACGG
+ATGAGGGATTGGTTCTTAAAGTTGGTTATTTGTGGAACTTCAAGGTAGTT
+GTGATGTCTAAAGATTAAGGTTAAGAAACCAAATATTTTAAGTTTAAGAT
+AAATAAATAAAAACTTTTCAGGCATCGTCCGTAATTATCGGTAATTCGGA
+ATGATTTTAGATCTCAAGACCAGAAAAATTTTTGCGAAATATTCAAAATT
+TAATCGATAAAAATTTTAGGTGGAAAATTCAATTTCAATTTTTAAAAATT
+TTGGACCGGAAATTGAACTGCAAACTCTACGAAATGGCCGATTGCACCAT
+GTTGTTCGGACATTTTTAATTAAAAATTAGTATCAAAATTTTTTTCAAAT
+GAATTTAAAAAAATTACCTGATTTATTTTAAAATCCCATTAGTCTCAGCT
+AGCACGTTTTAAAAAGTACTCAGAACTGTTCTGAAAATTGTAAATTACTG
+GTAAACAAAATTCGACAATTCCATATTCTACTAGTGGCAACTTTCAAATC
+ATTTTCGAGCATTTTCTTAAATATTTCAGCTAAACAATGGGATTTTCGGA
+TTAATCAAATAATTTTCTATATTTTGACATTAATTTTCGATGAAAAATAT
+AGGAACTGCATGGTGCAGTGTGTCATTTTGCAGAATCGCCGAAAATAACT
+GTCGCACATTCTTGATTGAAACTTCATTTTTTTAATTGGCGCGAAATTCA
+AATTTTAATTTTTAAATATTTTAGGCGGAAACCTCAGACTTCAACTTTCG
+AACCATTTTGACTGAAAAATCATACTTTAATTTTCAGAAATTAATGAAAT
+CAGCATTATTGTAGATGTTTCGGCGCACACCGTTGGCCTGTGGGTTGGCC
+GGTAGGCATATAAGTGCCTATATGAGATGTTGATCTAGAAATTAAAAATA
+GACAAATTTCTAATCTAGGATATTTAACTGTTCAGTTTTGTTTGTCATAT
+TTTCTGCTTTCAAATGTTTTCAATTTCTTCTCCTCTTTTCATATTTTTCA
+TTTGCACTTCACATCAAAGTTTTATTGTCAGAGGACCTAGTAAATAAATA
+CATTTTTCATTCTCTCACATGCTGGTGTTTGATGTTCAGTTAAAAATGTT
+TTTGATTCTGCAGGAAAAAAAAGAAGAAAAAGTCAACATACAGTACCGGT
+TCATTTGATTTCATCGTTTTGGAATTACAGAAAAATACTGGAACTAAATA
+AATAAATTTAAAAACAAAATAGAAAAAAATCAGATTTTCAAAACAATATA
+ATTCCTATTAGCATTATAAACTATTTTAAATGGAGCTATTCGTGAATTGT
+CTTTTGAATTTGCAGCAAGTATCCAAAGATCACAAAGAGCTGTTCGACCA
+CTATTCTTTGGATCTTCTTCATCCCACATTCCACGATAAACACATTCTGG
+CCTGAAAAATAGGTTTTTTTTAAATGAACATTATTGTTCCGATTTTTATA
+CCTCCTCTCATCATTTGAACAATTCATAAGTTGGAAAACAAAATAATTGA
+CACCCATTTCTTTCATTATTTTGTGAACTTCCGCGATTGGTTTTTTACTA
+AACATAGAATACACTTTCAGAGTTCGTTCACTGAAACAAACAAGGTTTAA
+TACTTTCTAGAGAAAATTAACAAATTACCGTATTCCAACATGTTCATAAT
+GAGGGTGATTGACAATTGGCCTAAGAGTTGTGAGCTTCACATTTGCCATT
+ACTGGCATTGTTCCAGCGAACACAGCGTCTGAAAAAAGTTATTTTGAAGC
+TAATATGGAAGGCAGGCATGTCTTCAGATGTACGTGCCTGCCTACCACTT
+CGGTGGTAAGTTTGTATATTACCTTGTTTGGTGTTATGTTGAATCCAGTC
+AAACAACATTTCTTGATCAGGATTACTGTATTCTCCCTTGACATTCAACT
+GTTGACGGATATTTGGAATTCCTGAAGGATGAATAAATATTTAGTAATGC
+AGTGAAAGAATTCAAACCTCTATAAAATAATATTGCGATCACTCCAACAA
+GAGCAGAAACTCGTATAGTTTTTGATATTCGATCTCCCCCCAGCAGCTTG
+GAGTTTGCAAAAAGTGCAGCAACAATACATAAATGAGGTGTCATGAATAG
+TTTGAGACGCATTATCAGGAATGCCATGACAGTTGAACAGCAGAGTTGGA
+CCACATTATATAGAATCTGAAATGCCAAATTGTAACTTTTTAGTTTCAAA
+AGTTATAGTATTGAAGCTGAAAACAATAATCTTAAAATTTTAAAATTTTA
+AACAAAGCTGTATTTTATTTTTCTATTTTTTTAATAATATTTTTTAAATA
+ACCACCGATCTGCCAGATTCAAAATAGTTGTTTTAAAATTTGGAAATTAC
+CTCTCCATTTTCTCCAATTTCTTCACTATTCCTCCATAATAAATTCGTAT
+TTTTCACAAAGTTAAAAACGAAAGTGACAAGAGAAATGAGGGCAAGTGGA
+ATAAGAAGTGTTCCACACAATTTCTCAATTGTTGAATATTGAATAAAATC
+GAATTCAGCTGAACAAGTATACAGTCTCGTGTGAAAGTTGGCAAAACTTG
+TGAATTTTGAACGAAGAATATCAAAGATATGAGCCTGAAATCATTAATTG
+AAACACAATACAATAAAAACGATAACCAACATCATCTTCAATTCCAAGTC
+CTTTTGACAATCCAATTTTAAGCCCAAGAGTAATTGATGCAAAGATGATA
+GCCAGGAAAAGAACATAAGCTGGACGGAATTTAAGATTTGAGAGTAGAGG
+AGAGATGTATATGATCATCTGGAAGCTTTTTGAAATTTATTTTTATCTAG
+TTTTTTTTTTTTTGGATTTGAGTTTTTACCCGAAAATTGTATAAGAGACA
+TAAACTATTTTTAGTTTCTCTATTCAATAGAAAACTTACCCCCAATGCCA
+AAATACTTGGAAAATACAATGCAGTAATCATCATCTCGTTACCAAAAAGC
+AGCAAAAATCCAATGAGAAATGAAATGATATGAGAATGAATTACTGTTTT
+AGCAGTAGAGAATGGAATCAGATCCAGTGAAAACGCTAAGAATATTGAAC
+AAATTTGTGTGAAAAATGCAAATTGGGTGAATTGCCAGAATAAAAGAGCT
+GGAACTGCCATGGAAGTTAAAAGAAGAATCATTGAGTGACCAGACTTTTT
+ATATCTGGAAAAATGAGTTTTGAGAACATCATATGCCAAAGAAAATTAGC
+ATTGCTACGTCTCGCATTTTCGTCATTTTTTTTGTCATAACTTACTTGAT
+AACAAATGTCAAAATCGCAATATGCCCGATAATAAACGGAAAAGCAAAGC
+TCTCCCGAAGAGGAGGTGTCCATTGAACTCGAGTTGCTTCTCCGTGATTA
+AATGCAAAACATAATACTGACAAGAATCCTCCGAATATTGAATCACTGTA
+ATATATATATTTAGTTAAAAGTAATAATTTTTGTGTCGCTCACCTAACAA
+GAACACCCAAATAAAAAATGGATGAAGCTACAGTTCCAGCCACAATGAAA
+ACTCCGGTTATATAGAAATAATGAGGATTTCCAATTCCTTCACAACTTTC
+AACAGGCCGAAGTTCTCCTCGATTAACTTGCCAGCATAGTTCGATTTGCC
+AATTCGCTGATTTGGCAAATGCTCGGAATGGGCGGTACAGAAATGCAAGG
+ATTACCTAAAATAAGCTTGGAAGGATTTTAGGTATGGAGGAAATTGAGAG
+AAAATGTAATACAGGTGAATGTATTCTTGTGGTAATTAGAAGTTTGCCAA
+AGGTTTTTCCGACGGAAAACATTACAATGTGAAAACTTTGCGACTCACCT
+CTGGATATAAATTAAATCGATTTAGTGTGTTAATCTCGTGTCCATGTTCT
+GTCACAGTATCATGTGTTATCTCCTGAACACCCTCAAGAAATGATGGTGC
+ATTGATTATTGTTTTATAGTATGAATAGTAGAGACCCTGAAAAAACAAGA
+AATTTTGAATTTGTATTTTTAAAGAAAACTGTACCATTTCCGTTCGATAT
+GCCATCTCGCGTTCAAAGTCCGCCAAATGGGAGAAATGTTTGTCGTTTTC
+GAATAATGTGTAGACATGTTGGTAGTTGATGTATCCAACGAGGAGTCCTG
+AAAATAAAAAAAACTGTATTGAAATTCGTTTGAGCGTAAAATAATTTGTC
+GCAAGTTTGATAAAGATCCGAGAAGACTATTTCTGTAACTTGCATGATTG
+TCTGCCAACTAATTATTTTCTGAATTTTTCTGTCAGGTCACATGCCATAT
+CCGGGTGGAACAGGACCACTTTAGAGATTGATACGGCTCTAGTTTAATGA
+AGAGCAAAAAATCTGCAGGTAGGTCAGTAGGTAGGTGTTGTAAGCAGGCA
+GACATTTTGAACCCTACATGGACACCCCATTTCAAATAACTACTATTAAA
+ACATAGTTTTCTTAAAAAAGTATTTAATTTGTTTCCCCACCCAATTGCTC
+TTAATAATCCTCATTGGTTCTCCTAGTTTTACTCTTTTGTTCCCATTTCC
+CTTTTTTTGCAATTCAAAACACATCCAGTTTTGAGAGAGAGGTCTCTCTC
+TCTGTCCCTCTCTACCTCCCCCTCTCTCTGTAATTATCGACTTTGGGGAC
+GAAATGTCAGTTCATTTGTGGAAATAGTTTATGAATCGGAGAGACTTTAG
+ACACTTTGAACAAACCGTGTCGTCGTCAGTGACGAGACACAAACACAGGA
+AGTTTCGTTGAATATGTTGATGTTTCTGTTGACGTTTCGTTCCCTAGTTT
+TTAGAGATTGAGAGCATCTAAGGATTAAGGTTCAATGTTTCAAGATTTAA
+AGTTTTGAAACATAAGTAACAGAGTAAATGATATGATTTAGATAATTTTC
+TTATTTTTTAATCTGGCAAGCACGCTCAACTAACAAAACACGAATCCGAC
+AATCAGTCAAACATCTTAAACTTTTTAAAAAATTGTTCATTCTTTATAAG
+AGCGAATTTCAAATTTAAAAAAAACTTTAATTAAGCTTCAGGTCAAGCAA
+TTAGGCGTTATTATTAATTCTGGCAAGTTTCCGTTTTTCAGATATAATCA
+TTTCAATTTCGATTCTTTCTTCAAAGTGTCTGGAAAAAATGCTCTTTTTT
+AATAATTTCGCCGAATCTAATAGTTCTAAAATTTTATGTTGAAACGATCA
+ATTCTATAACAGTATATTCAAAAATAACCTCACTAAACTTGAATTTTTTC
+CAAAAAAAAGCATTCAAAGTGAGCAAATAGTTTTGGTAATACAGGTGGCT
+ACAAATTTTCTGTCAAAATGTTCAATACACAAAGTGTGAGCAAGAGCAGA
+ACCAGTTTTCAAACATATTGCTCTCAGTTCTCACTTTCATTTTTGTTTGT
+ATTAGAGGCTCATTGAGCAATAGCAACTTGAACTTTACTTACTGTTTGTA
+ATAGCTTAACTGTTCACATTTTTACTAAAACTTTGCAACCTATAGGTATA
+CCTAATAATTGGGTTTTTCAATTTTGTATGAGAAATCACATCCCGAAACT
+GAATGGAAACTTTCTGATTAAAATGGATATCACTTCAAACATAGTGTCTT
+TTAATATTGTCTAAGCCTGTATGACAGTGATAATTTCTAATAAAGAGGCG
+CAGAGAAATTAGATAATGACCGATAATGATGAGATGAATGAATGTAATGA
+TGTGGGAAAATAGATAATAGAATAAGAAGTGTGGGCATAATGATTTAGAT
+GATAGAAGCGTTCAGTCTAGGAATCATTTCAAGTCAATATCACTAATTAT
+CTCATTTATTTTTGTTCCTTTGATTTATTCGTTTTGGTAGGGCCGTTTCA
+TCTTAAAGCGTATATTCAAAACAATTAAAAAATCGTTTTTGAAGTCTTCC
+AAGTAAAAATAAATATCTGCTTTGTGCCTATATTGCGCACCTATCATTTA
+ATTTCTTAAATGGGGCGTAGCAATTTTGGACTTCTGCTTCAATATCTTCA
+AAATGATCCCAATAGACCGAATTTCATAATGTGACTCCTCGAAAATTTCT
+TATGAAGATACAACATTTTAACACTGTTTTCTTTCATAGTGTCCAACGCC
+TGCCTTTTTCCTACACTAGTTTTTTTTTCAATATCCTTGCAAGTGCACCT
+GCAAGAAAAGTTTAACAAAAGTTCTTAAACTTAAAAAAGTAGGTGGTAGG
+CAGGCACGTAGGTGCGCAGGTATGTAGCCAATAGATTCTCAAAATATAAT
+TATAAAAACTCTGCATTTCTTTTTATTCATCCTAAAAGCGCATTCTACTC
+AAAACCCAGTCACATGCTCTATTCACAAAAGTCAATTTTTTTTCATCTGC
+TCTCCGCATAAACTCTTGCTTCCAATTTCCAGATGCATTTAATGTCACGT
+GCGTTCACTTTTTTCCCTTCAAGCTTCCAGAACAAAAAAGTCTTGTGATG
+TTTCGCTCAGAAATTTGTTTGAATAGATGATAATTGGATTTCGGTTGAAT
+TATTTTTGCCATCGCATGTCCTTTCTTCAATTCTCAATTTCCAGTTTTCG
+TGTGATTCTCCAAAAGTTTCAAACATCATCCGAATTTTCTTGTTTTTCTA
+TTATGTCACTGATTTCCTATTTATTTTTCATATTTTTAAAGTTTTTTTTA
+AGGGAAAATGAAAACGCCTGCAATTTTATTACTCCTATTCTTATTTATGA
+TGAGTTTGGCACAAAGTGATGAGGAACAAAGTGGAAAGGAACCTCCCGAA
+AAAGATGATGTTCTAGTTATTCTGGTTGGTTTTTGCCAATGTTACCATGT
+CAGAAATGCATGCATGCCTACTTTCGGCACATCTTCGTTTTCTTTTCCCG
+TATTCTATGTTTTAATTTTCAGGCAGAAGACAATTCGACACTATTAAACA
+ATAACCAAACAATGTATGACCCTTCTTCCGAAGAAAAAGAAAGTGACAAA
+CCAAAATTCAATTTATTGGAGACATATTTACCACTTTTCATATTTGTACT
+CGATCTACCAACAGAGGATAGAGAAACTTTGAAAGCCTATGTAAAAGATA
+AAACTTATGAAAAACTGAAATATGTAATCGATTCAAAAGTTAAAATGAAT
+CGAAATGAGAAAAATGTCTTAGGAAGAATCAATGAATCCTTGGTACAATC
+AATCGATAATTTGGAACATTTTGATGAGATTACTGTAGATGTGGTGAATG
+GTTATCACGTAAGTTTGACATTTCAATGGAAAATCATCTCTCTTTAATCT
+TTAAAATGTTTTATTTTCAAAAAAAACCTTAATATGACAATACCAAATTT
+TCCTTCTATAACTAAATTTCTAGAATGCCTCCGTATACAACGCAATCCGT
+TCAGTTTGGTTGAAACAATTACGTCCATTTCTGCCGCTAATTGATCAAAT
+GGCCATTCAGCAGTATTTTGCACAAAGGTTTCAAACATCAAGCGTCTATC
+AAAAACTATGTTTATTTTCCAGAAAATCTTCTGAAACTGAGAAAATGTCA
+ATTTGGGCAAGATTATGGGAAAATCTGAGTGTTTGGATGTATGGAAAGAA
+AAAATTAAACGAATGTTATGCAATGGAGCCAAAATGTGTTCGACACGCAT
+TGGAATTGCTTAATTTTGAACAAAGGATTGATTTGGATTTAGCTGCTTAT
+GAGAACAAGTTTGACAGTGTTGATGGAATTATTAGGGAAAGAGTGAGTCA
+ATTTAGATATTTAAAAAATGTCAAAAGCCCCAAAACGAATTAATTTTCAG
+CTTGGCGAAAATCGGAAAAGCAGTGAACTCGACGAATGGTTGCACAGAAA
+TCGCCCACCAAAAGCGCTACAAGCTATTTTAGATGAGCGAAGTGACATTG
+AGGAGGAGTAAGATATTTATATTGAATAGATAAACGTTAGATTTTTAGAG
+CTCTTCAACGCCTTCGAGATAACGGAGTTCTGAGCTCACTCAAACATTAT
+TACAAAGCAGTTATAGAGTCAAGAAGTCATGAAGAGCAAGAGGTAACCAA
+TGTTTTAGATAGTTCTTGTCAATTTTCTTACGCATTTTTCGATATTCTGC
+TAATGGGTGCAAAGTTCTAAATTGTTTTTAATTGTAGCTTTCTATATTAA
+ACTTTCAGGACATTCGTCATTTCTTCGACATAATGAATGACACATTTGCT
+CGTTGCTTTGACCCACTACGAGGCCAGTATCATGATTTCTAGAAAAACCC
+TCTTTTTGACTTCTTCCTCCAT
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/r17.bob	Mon Dec 22 09:08:31 2014 -0500
@@ -0,0 +1,1 @@
+ 22801  22817        F22B7 921215/f22b7.seq
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/r17.des	Mon Dec 22 09:08:31 2014 -0500
@@ -0,0 +1,13 @@
+# r17.des
+#
+# descriptor of the consensus binding site for the phage R17 coat
+# protein: a stem with a single-base A bulge and a 4-base loop
+#
+
+
+h1 s1 h2 s2 h2' h1'
+
+h1 0:0 NNNN:NNNN
+h2 0:0 NN:NN
+s1 0   A
+s2 0   AUYA
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/trna.bob	Mon Dec 22 09:08:31 2014 -0500
@@ -0,0 +1,5 @@
+ 11092  11167        F22B7 921215/f22b7.seq
+ 28644  28556        F22B7 921215/f22b7.seq
+ 28643  28556        F22B7 921215/f22b7.seq
+ 28635  28556        F22B7 921215/f22b7.seq
+ 28630  28556        F22B7 921215/f22b7.seq
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/trna.des	Mon Dec 22 09:08:31 2014 -0500
@@ -0,0 +1,19 @@
+# trna.des
+#
+# Generalized descriptor of a tRNA cloverleaf. Doesn't
+# find them all though. 
+#
+
+h1 s1 h2 s2 h2' s3 h3 s4 h3' s5 h4 s6 h4' h1' s8
+
+h1 0:2 NNNNNNN:NNNNNNN
+h2 0:1 *NNN:NNN*
+h3 0:1 NNNNN:NNNNN
+h4 0:1 NNNNN:NNNNN
+s1 0 TN
+s2 0 NNNN**********
+s3 0 N
+s4 0 NNNNNN*
+s5 0 NN********************
+s6 0 TTC****
+s8 0 NCCA
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool_dependencies.xml	Mon Dec 22 09:08:31 2014 -0500
@@ -0,0 +1,21 @@
+<?xml version="1.0"?>
+<tool_dependency>
+    <package name="rnabob" version="2.2.1">
+        <install version="1.0">
+            <actions>
+                <action type="download_by_url" target_filename="rnabob-2.2.1.tar.gz">http://selab.janelia.org/software/rnabob/rnabob.tar.gz</action>
+                <action type="shell_command">make</action>
+                <action type="move_file">
+                    <source>rnabob</source>
+                    <destination>$INSTALL_DIR/bin</destination>
+                </action>
+                <action type="set_environment">
+                    <environment_variable name="PATH" action="prepend_to">$INSTALL_DIR/bin</environment_variable>
+                </action>
+            </actions>
+        </install>
+        <readme>
+Compiling rnabob requires a C compiler (typically gcc)
+        </readme>
+    </package>
+</tool_dependency>