# HG changeset patch # User trinity_ctat # Date 1531842433 14400 # Node ID f92fcdde48fc11e9b4a17e34e388fe8e568765c3 Upload ctat tools. diff -r 000000000000 -r f92fcdde48fc ctat_metagenomics.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/ctat_metagenomics.xml Tue Jul 17 11:47:13 2018 -0400 @@ -0,0 +1,109 @@ + + + Centrifuge classifier for metagenomic sequences (RNA-Seq) + + centrifuge + ctat-metagenomics + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +.. class:: infomark + +ctat_metagenomics is a component of the Trinity Cancer Transcriptome Analysis Toolkit (CTAT). CTAT's metagenomics is a classifier for metagenomic sequences (RNA-Seq) for foreign transcript detection. It leverages Centrifuge, a novel microbial classification engine that enables rapid, accurate, and sensitive labeling of reads and quantification of species, and Kraken. As well, we are leveraging RNA-Seq reads and Trinity-reconstructed transcripts. Our efforts here are being carried out in collaboration with the group of Steven Salzberg at JHU. + +For more information: + +https://ccb.jhu.edu/software/centrifuge/manual.shtml#what-is-centrifuge + + + + 10.1101/gr.210641.116 + + + diff -r 000000000000 -r f92fcdde48fc test-data/centrifuge/SRR2219890_1_20k_reads.classification.report.txt --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/centrifuge/SRR2219890_1_20k_reads.classification.report.txt Tue Jul 17 11:47:13 2018 -0400 @@ -0,0 +1,8 @@ +name taxID taxRank genomeSize numReads numUniqueReads abundance +root 1 no rank 0 370 370 0.0 +Bacillus 1386 genus 5402033 31 31 0.0 +Homo sapiens 9606 species 3238442024 4384 4384 0.00519472 +synthetic construct 32630 species 26537524 8 8 0.000787552 +Methanocaldococcus 196118 genus 1584277 1 1 0.0 +Methanocaldococcus jannaschii DSM 2661 243232 leaf 1739927 50 50 0.994018 +Leptotrichia buccalis C-1013-b 523794 leaf 2465610 1 1 0.0 diff -r 000000000000 -r f92fcdde48fc test-data/centrifuge/SRR2219890_1_20k_reads.kraken_style_report.txt --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/centrifuge/SRR2219890_1_20k_reads.kraken_style_report.txt Tue Jul 17 11:47:13 2018 -0400 @@ -0,0 +1,58 @@ + 2.67 133 133 U 0 unclassified + 97.33 4845 370 - 1 root + 89.73 4467 0 - 131567 cellular organisms + 88.07 4384 0 D 2759 Eukaryota + 88.07 4384 0 - 33154 Opisthokonta + 88.07 4384 0 K 33208 Metazoa + 88.07 4384 0 - 6072 Eumetazoa + 88.07 4384 0 - 33213 Bilateria + 88.07 4384 0 - 33511 Deuterostomia + 88.07 4384 0 P 7711 Chordata + 88.07 4384 0 - 89593 Craniata + 88.07 4384 0 - 7742 Vertebrata + 88.07 4384 0 - 7776 Gnathostomata + 88.07 4384 0 - 117570 Teleostomi + 88.07 4384 0 - 117571 Euteleostomi + 88.07 4384 0 - 8287 Sarcopterygii + 88.07 4384 0 - 1338369 Dipnotetrapodomorpha + 88.07 4384 0 - 32523 Tetrapoda + 88.07 4384 0 - 32524 Amniota + 88.07 4384 0 C 40674 Mammalia + 88.07 4384 0 - 32525 Theria + 88.07 4384 0 - 9347 Eutheria + 88.07 4384 0 - 1437010 Boreoeutheria + 88.07 4384 0 - 314146 Euarchontoglires + 88.07 4384 0 O 9443 Primates + 88.07 4384 0 - 376913 Haplorrhini + 88.07 4384 0 - 314293 Simiiformes + 88.07 4384 0 - 9526 Catarrhini + 88.07 4384 0 - 314295 Hominoidea + 88.07 4384 0 F 9604 Hominidae + 88.07 4384 0 - 207598 Homininae + 88.07 4384 0 G 9605 Homo + 88.07 4384 4384 S 9606 Homo sapiens + 1.02 51 0 D 2157 Archaea + 1.02 51 0 P 28890 Euryarchaeota + 1.02 51 0 C 183939 Methanococci + 1.02 51 0 O 2182 Methanococcales + 1.02 51 0 F 196117 Methanocaldococcaceae + 1.02 51 1 G 196118 Methanocaldococcus + 1.00 50 0 S 2190 Methanocaldococcus jannaschii + 1.00 50 50 - 243232 Methanocaldococcus jannaschii DSM 2661 + 0.64 32 0 D 2 Bacteria + 0.62 31 0 - 1783272 Terrabacteria group + 0.62 31 0 P 1239 Firmicutes + 0.62 31 0 C 91061 Bacilli + 0.62 31 0 O 1385 Bacillales + 0.62 31 0 F 186817 Bacillaceae + 0.62 31 31 G 1386 Bacillus + 0.02 1 0 P 32066 Fusobacteria + 0.02 1 0 C 203490 Fusobacteriia + 0.02 1 0 O 203491 Fusobacteriales + 0.02 1 0 F 1129771 Leptotrichiaceae + 0.02 1 0 G 32067 Leptotrichia + 0.02 1 0 S 40542 Leptotrichia buccalis + 0.02 1 1 - 523794 Leptotrichia buccalis C-1013-b + 0.16 8 0 - 28384 other sequences + 0.16 8 0 - 81077 artificial sequences + 0.16 8 8 S 32630 synthetic construct diff -r 000000000000 -r f92fcdde48fc test-data/centrifuge/SRR2219890_1_adj_20k_reads.fastq --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/centrifuge/SRR2219890_1_adj_20k_reads.fastq Tue Jul 17 11:47:13 2018 -0400 @@ -0,0 +1,20000 @@ +@HWI-D00361:29:H8HM6ADXX:1:1101:1238:2179/1 +CGCTCCCCTGACACGTAGGCNNNCATACTGATGCGGTATTGTGCCAGCAT ++SRR2219890.1 HWI-D00361:29:H8HM6ADXX:1:1101:1238:2179 +<< +# value is a unique id +# name is the display name +# path is the directory where the index files are stored +# +#ctat_centrifuge_indexes.loc could look like: +# +#p_compressed+h+v CTAT_CentrifugeIndex_p_compressed+h+v /path/to/centrifuge/index/p_compressed+h+v +# diff -r 000000000000 -r f92fcdde48fc tool_data_table_conf.xml.sample --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_data_table_conf.xml.sample Tue Jul 17 11:47:13 2018 -0400 @@ -0,0 +1,14 @@ + + + value, name, path + +
+ + value, name, path + +
+ + value, name, path + +
+