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1 #!/usr/bin/env python
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2
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3 # Copyright INRA (Institut National de la Recherche Agronomique)
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4 # http://www.inra.fr
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5 # http://urgi.versailles.inra.fr
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6 #
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7 # This software is governed by the CeCILL license under French law and
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8 # abiding by the rules of distribution of free software. You can use,
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9 # modify and/ or redistribute the software under the terms of the CeCILL
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10 # license as circulated by CEA, CNRS and INRIA at the following URL
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11 # "http://www.cecill.info".
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12 #
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13 # As a counterpart to the access to the source code and rights to copy,
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14 # modify and redistribute granted by the license, users are provided only
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15 # with a limited warranty and the software's author, the holder of the
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16 # economic rights, and the successive licensors have only limited
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17 # liability.
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18 #
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19 # In this respect, the user's attention is drawn to the risks associated
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20 # with loading, using, modifying and/or developing or reproducing the
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21 # software by the user in light of its specific status of free software,
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22 # that may mean that it is complicated to manipulate, and that also
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23 # therefore means that it is reserved for developers and experienced
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24 # professionals having in-depth computer knowledge. Users are therefore
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25 # encouraged to load and test the software's suitability as regards their
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26 # requirements in conditions enabling the security of their systems and/or
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27 # data to be ensured and, more generally, to use and operate it in the
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28 # same conditions as regards security.
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29 #
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30 # The fact that you are presently reading this means that you have had
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31 # knowledge of the CeCILL license and that you accept its terms.
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32
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33 from operator import itemgetter
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34 from commons.core.coord.Range import Range
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35
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36 class SequenceModifications(object):
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37
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38 def __init__(self, originalHeader = "", mutatedHeader = ""):
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39 self._originalHeader = originalHeader
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40 self._mutatedHeader = mutatedHeader
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41 self._lMutations = []
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42 self._lDeletionsRanges = []
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43 self._lInsertionsRanges = []
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44
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45 def __str__(self):
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46 result = "%s\t%s\n" % (self.getOriginalHeader(), self.getMutatedHeader())
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47 result += "Insertions\n"
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48 for insertion in self._lInsertionsRanges:
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49 result += "%s\n" % insertion.toString()
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50 result += "Deletions\n"
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51 for insertion in self._lDeletionsRanges:
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52 result += "%s\n" % insertion.toString()
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53 result += "Mutations"
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54 for mutation in self._lMutations:
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55 result += "\n%i\t%s\t%s" % (mutation[0], mutation[1], mutation[2])
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56 return result
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57
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58 def __eq__(self, o):
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59 if type(o) is type(self):
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60 self.sort()
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61 o.sort()
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62 return self._originalHeader == o._originalHeader and self._mutatedHeader == o._mutatedHeader and self._lMutations == o._lMutations \
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63 and self._lDeletionsRanges == o._lDeletionsRanges and self._lInsertionsRanges == o._lInsertionsRanges
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64 return False
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65
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66 def __ne__(self, o):
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67 return not self.__eq__(o)
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68
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69 def getOriginalHeader(self):
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70 return self._originalHeader
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71
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72 def getMutatedHeader(self):
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73 return self._mutatedHeader
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74
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75 def getMutations(self):
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76 self.sort()
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77 return self._lMutations
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78
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79 def getInsertions(self):
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80 self.sort()
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81 return self._lInsertionsRanges
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82
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83 def getDeletions(self):
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84 self.sort()
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85 return self._lDeletionsRanges
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86
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87 def setOriginalHeader(self, originalHeader):
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88 self._originalHeader = originalHeader
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89
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90 def setMutatedHeader(self, mutatedHeader):
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91 self._mutatedHeader = mutatedHeader
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92
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93 def setMutations(self, lMutations):
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94 self._lMutations = lMutations
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95
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96 def addMutation(self, tupleMute):
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97 #tuple: (position, oldNT, newNT)
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98 self._lMutations.append(tupleMute)
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99
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100 def addInsertion(self, start, end, insertedSeqName = "."):
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101 self._lInsertionsRanges.append(Range(insertedSeqName, start, end))
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102
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103 def addDeletion(self, start, end):
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104 self._lDeletionsRanges.append(Range(self.getOriginalHeader(), start, end))
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105
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106 def clear(self):
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107 self._lMutations = []
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108 self._lDeletionsRanges = []
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109 self._lInsertionsRanges = []
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110
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111 def sort(self):
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112 self._lMutations.sort(key = itemgetter(0), reverse = False)
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113 self._lDeletionsRanges.sort(key = lambda delRange: delRange.getStart(), reverse = False)
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114 self._lInsertionsRanges.sort(key = lambda insRange: insRange.getStart(), reverse = False) |