diff rDiff/src/tools/read_utils/splicingsequence.m @ 0:0f80a5141704

version 0.3 uploaded

--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/rDiff/src/tools/read_utils/splicingsequence.m	Thu Feb 14 23:38:36 2013 -0500
@@ -0,0 +1,37 @@
+function [SPLICINGEVENTS, SEQUENCE, EXONSEQUENCE, IDENTIFICATIONLENGTH] = splicingsequence(GENE)
+% This function generates all sequence of all splicesites
+% SPLICINGEVENTS, a SEQUENCE marking which elements in
+% SPLICINGEVENTS are introns and exons and a sequence for each
+% transcript which indicates which Exons are in cluded in this transcript
+% SEQUENCE contains indices of SPLICINGEVENTS, containing 1, if the position right to the idx in the transcript
+% are exonic, 0 otherwise
+
+  EXONS = GENE.exons;
+  START = GENE.start;
+  STOP = GENE.stop;
+  
+  NB_OF_TRANSCR = size(EXONS,2);
+  
+  SPLICINGEVENTS = [];
+  for i = 1:NB_OF_TRANSCR
+    SPLICINGEVENTS = [SPLICINGEVENTS, EXONS{i}(:,1)', EXONS{i}(:,2)' ];
+  end
+  SPLICINGEVENTS = SPLICINGEVENTS - START + 1;
+  SPLICINGEVENTS = unique(SPLICINGEVENTS);
+  
+  EXONSEQUENCE = zeros(NB_OF_TRANSCR, length(SPLICINGEVENTS) - 1);
+  
+  for i = 1:NB_OF_TRANSCR
+    %%% for every exon in transcript i
+    for j = 1:size(EXONS{i}, 1)
+      POS_START = find(SPLICINGEVENTS == EXONS{i}(j,1) - START + 1, 1, 'first');
+      POS_STOP = find(SPLICINGEVENTS < EXONS{i}(j,2) - START + 1, 1, 'last');
+      %%% set splicing events active in transcript i to 1
+      EXONSEQUENCE(i, POS_START:POS_STOP) = 1;
+    end 
+  end
+
+  %%% merge active splicing events of all transcripts
+  SEQUENCE = max(EXONSEQUENCE, [], 1);
+  IDENTIFICATIONLENGTH = [];
+