# HG changeset patch # User yating-l # Date 1492033067 14400 # Node ID 57299471d6c1ef7645f8ddea25151cedfdd8dc86 planemo upload commit 402a746f69e9f1dbb57007536fc36dc6ce3180de diff -r 000000000000 -r 57299471d6c1 Group.py --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/Group.py Wed Apr 12 17:37:47 2017 -0400 @@ -0,0 +1,59 @@ +from operator import itemgetter + +# Input: A group: a list that contains lines belonging to the same gene +class Group: + # Modify "type" column and "attributes" colunm, initialize id, gene, source, stream + def __init__(self, group): + self.group = group + self.id = str(group[0][0]) + self.source = str(group[0][1]) + self.stream = str(group[0][6]) + self.gene = str(group[0][8]) + for x in range(0, len(group)): + self.group[x][2] = "CDS" + self.group[x][8] = "Parent=mRNA_" + self.gene + self.group[x][3] = int(self.group[x][3]) + self.group[x][4] = int(self.group[x][4]) + + # Order the group elements accoriding to Stream, +: ascanding order, -: descanding order + def order(self): + self.num = len(self.group) + if self.stream == "+": + self.group = sorted(self.group, key=itemgetter(3)) + self.min_item = self.group[0][3] + self.max_item = self.group[self.num-1][4] + elif self.stream == "-": + self.group = sorted(self.group, key=itemgetter(3), reverse=True) + self.min_item = self.group[self.num-1][3] + self.max_item = self.group[0][4] + else: + print("Stream in invalid!\n") + + def phaseCalculator(self, i, donor = 0): + if i >= self.num: + pass + else: + self.type = self.group[i][2] + self.size = self.group[i][4] - self.group[i][3] + 1 + if self.num == 1: + if self.type == "Eterm": + self.group[i][7] = str(self.size % 3) + else: + self.group[i][7] = "0" + elif self.num > 1 and i < self.num: + accept = (3 - donor) % 3 + self.group[i][7] = str(accept) + donor = (self.size - accept) % 3 + i = i + 1 + self.phaseCalculator(i, donor) + + + def writer(self, gff3): + self.order() + self.phaseCalculator(0) + gff3.write(self.id + "\t" + self.source + "\tgene\t" + str(self.min_item) + "\t" + str(self.max_item) + "\t.\t" + self.stream + "\t.\t" + "ID=" + self.gene + "\n") + gff3.write(self.id + "\t" + self.source + "\tmRNA\t" + str(self.min_item) + "\t" + str(self.max_item) + "\t.\t" + self.stream + "\t.\t" + "ID=mRNA_" + self.gene + ";Parent=" + self.gene + "\n") + for x in range(0, len(self.group)): + self.group[x][3] = str(self.group[x][3]) + self.group[x][4] = str(self.group[x][4]) + gff3.write("\t".join(self.group[x]) + "\n") \ No newline at end of file diff -r 000000000000 -r 57299471d6c1 README.md --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/README.md Wed Apr 12 17:37:47 2017 -0400 @@ -0,0 +1,2 @@ +# SNAP +Galaxy wrapper for SNAP gene prediction tool diff -r 000000000000 -r 57299471d6c1 gff2Togff3.py --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/gff2Togff3.py Wed Apr 12 17:37:47 2017 -0400 @@ -0,0 +1,59 @@ +import argparse +import sys +import fileinput +from Group import Group + +def main(): + parser = argparse.ArgumentParser(description='Get a gff file and the output gff3 file') + parser.add_argument('--input', help='input gff file') + parser.add_argument('--output', help='output gff3 file', required=True) + args = parser.parse_args() + input = args.input + output = args.output + if not sys.stdin.isatty(): + c = Convertor(sys.stdin, output) + else: + c = Convertor(input, output) + c.convert() + +class Convertor: + def __init__(self, input, output): + if type(input) is str: + with open(input) as self.f: + self.li = [line.rstrip().split("\t") for line in self.f] + else: + self.li = [line.rstrip().split("\t") for line in input] + self.gff3 = open(output, "w") + self.gff3.write("##gff-version 3\n") + + def convert(self): + index = 0 + while index in range(0, len(self.li)): + index = self.groupAsgene(index) + self.gff3.close() + + + def groupAsgene(self, start = 0): + gene = self.li[start][8] + index = len(self.li) + for i in range(start+1, len(self.li)): + line = self.li[i] + if gene != line[8]: + index = i + break + if index >= len(self.li): + group = self.li[start:len(self.li)] + else: + group = self.li[start:index] + g = Group(group) + g.writer(self.gff3) + return index + + + + +if __name__ == "__main__": + main() + + + \ No newline at end of file diff -r 000000000000 -r 57299471d6c1 readme.rst --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/readme.rst Wed Apr 12 17:37:47 2017 -0400 @@ -0,0 +1,46 @@ +Galaxy wrapper for SNAP +======================== + +This wrapper is copyright 2016-2017 by Yating Liu + +This is a wrapper for the gene prediction tool SNAP. SNAP is a general purpose gene finding program suitable for both eukaryotic and prokaryotic genomes. SNAP is an acroynm for Semi-HMM-based Nucleic Acid +Parser. + +Reference +---------------------- + + Korf I. Gene finding in novel Genomes. BMC Bioinformatics 2004, 5:59 + +Installation +----------------------- + +To install SNAP, please download SNAP from + +http://korflab.ucdavis.edu/Software/snap-2013-11-29.tar.gz + +and follow the installation instractions. The software is routinely compiled and tested on Mac OS X. It should compile +fine on any Linux/Unix type operating systems. +The default compiler is gcc. If you have gcc installed, the easiest is to just compile as: +``` + make +``` + +The ZOE environment variable is used by SNAP to find the HMM files. Set this +to the directory containing this file. For example, if you unpackaged the tar-ball in /usr/local/snap, set the ZOE environment variable to /usr/local/snap + +``` + setenv ZOE /usr/local/snap # csh, tcsh, etc +``` + or +``` + export ZOE=/usr/local/snap # sh, bash, etc +``` +To install the wrapper copy the snap folder in the galaxy tools and modify the $GALAXY_ROOT/config/tool_conf.xml file to make the tool available to Galaxy. For example: +``` + +``` + + + + + diff -r 000000000000 -r 57299471d6c1 snap.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/snap.xml Wed Apr 12 17:37:47 2017 -0400 @@ -0,0 +1,170 @@ + + + snap + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + proteins == "-aa" + + + transcripts == "-tx" + + + + + + + + + + [options] + +HMM file: + + The most convenient way to specify the HMM file is by name. This requires + that the ZOE environment variable is set. In this case, snap will look + for the HMM file in $ZOE/HMM. You may also specify the HMM file by an + explicit path. The following are equivalent if $ZOE is in /usr/local: + + snap C.elegans.hmm ... + snap /usr/local/Zoe/HMM/C.elegans.hmm ... + snap worm ... # there are a few convenient aliases in $ZOE/HMM + +FASTA file: + + If you have several sequences to analyze, it is more efficient to run + snap on a concatenated FASTA file rather than separate runs on single + sequence files. The seqeuence may be in a compressed format + + If sequences have been masked with lowercase letters, use -lcmask to + prevent exons from appearing in masked DNA. + +Output: + + Annotation is reported to stdout in a non-standard format (ZFF). You can + change to GFF or ACEDB with the -gff or -ace options. Proteins and + transcripts are reported to FASTA files with the -aa and -tx options. + +External definitions: + + SNAP allows you to adjust the score of any sequence model at any point + in a sequence. This behavior is invoked by giving a ZFF file to SNAP: + + snap -xdef + + Each feature description uses the 'group' field to issue a command: + + SET set the score + ADJ adjust the score up or down + OK set non-cannonical scores + + >FOO + Acceptor 120 120 + +50 . . . SET (sets an Acceptor to 50) + Donor 212 212 + -20 . . . ADJ (lowers a Donor by -20) + Inter 338 579 + -2 . . . ADJ (lowers Inter by -2 in a range) + Coding 440 512 - +3 . . . ADJ (raises Coding by +3 in a range) + Donor 625 638 + -5 . . . OK (sets range of odd Donors to -5) + +If the output has scrolled off your screen, try 'snap -help | more' + + ]]> + + +@misc{renameTODO, + author = {LastTODO, FirstTODO}, + year = {TODO}, + title = {TODO}, + url = {http://korflab.ucdavis.edu/Software/snap-2013-11-29.tar.gz}, +} + + diff -r 000000000000 -r 57299471d6c1 test-data/thale.dna.gz Binary file test-data/thale.dna.gz has changed diff -r 000000000000 -r 57299471d6c1 tool_dependencies.xml --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/tool_dependencies.xml Wed Apr 12 17:37:47 2017 -0400 @@ -0,0 +1,25 @@ + + + + + + + http://korflab.ucdavis.edu/Software/snap-2013-11-29.tar.gz + make + + . + $INSTALL_DIR + + + $INSTALL_DIR + $INSTALL_DIR + + + + + SNAP is a general purpose gene finding program suitable for both eukaryotic + and prokaryotic genomes. SNAP is an acroynm for Semi-HMM-based Nucleic Acid + Parser. + + +