Mercurial > repos > yufei-luo > s_mart
annotate smart_toolShed/SMART/Java/Python/misc/Utils.py @ 4:1fc014126d55
Uploaded
author | yufei-luo |
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date | Fri, 18 Jan 2013 04:45:50 -0500 |
parents | e0f8dcca02ed |
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rev | line source |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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1 # |
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2 # Copyright INRA-URGI 2009-2010 |
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3 # |
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4 # This software is governed by the CeCILL license under French law and |
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5 # abiding by the rules of distribution of free software. You can use, |
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6 # modify and/ or redistribute the software under the terms of the CeCILL |
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7 # license as circulated by CEA, CNRS and INRIA at the following URL |
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8 # "http://www.cecill.info". |
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9 # |
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10 # As a counterpart to the access to the source code and rights to copy, |
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11 # modify and redistribute granted by the license, users are provided only |
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12 # with a limited warranty and the software's author, the holder of the |
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13 # economic rights, and the successive licensors have only limited |
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14 # liability. |
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15 # |
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16 # In this respect, the user's attention is drawn to the risks associated |
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17 # with loading, using, modifying and/or developing or reproducing the |
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18 # software by the user in light of its specific status of free software, |
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19 # that may mean that it is complicated to manipulate, and that also |
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20 # therefore means that it is reserved for developers and experienced |
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21 # professionals having in-depth computer knowledge. Users are therefore |
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22 # encouraged to load and test the software's suitability as regards their |
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23 # requirements in conditions enabling the security of their systems and/or |
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24 # data to be ensured and, more generally, to use and operate it in the |
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25 # same conditions as regards security. |
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26 # |
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27 # The fact that you are presently reading this means that you have had |
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28 # knowledge of the CeCILL license and that you accept its terms. |
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29 # |
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30 """Some useful functions""" |
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31 |
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32 import sys, os |
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33 import random |
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34 import subprocess |
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35 |
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36 |
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37 def writeFile(fileName, content): |
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38 """ |
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39 Write the content of a file |
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40 """ |
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41 handle = open(fileName, "w") |
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42 handle.write(content) |
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43 handle.close() |
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44 |
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45 def sumOfLists(list1, list2): |
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46 """ |
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47 Element by element sum |
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48 """ |
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49 if len(list1) != len(list2): |
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50 sys.exit("Cannot sum list whose sizes are different!") |
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51 return [list1[i] + list2[i] for i in range(len(list1))] |
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52 |
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53 |
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54 def protectBackslashes(string): |
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55 """ |
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56 Protect the backslashes in a path by adding another backslash |
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57 """ |
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58 return string.replace("\\", "\\\\") |
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59 |
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60 |
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61 def getHammingDistance(string1, string2): |
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62 """ |
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63 Compute Hamming distance between two strings |
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64 """ |
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65 if len(string1) != len(string2): |
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66 raise Exception("Error, size of %s and %s differ" % (string1, string2)) |
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67 return sum(ch1 != ch2 for ch1, ch2 in zip(string1, string2)) |
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68 |
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69 |
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70 def getLevenshteinDistance(string1, string2): |
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71 """ |
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72 Compute Levenshtein distance between two strings |
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73 """ |
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74 if len(string1) < len(string2): |
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75 return getLevenshteinDistance(string2, string1) |
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76 if not string1: |
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77 return len(string2) |
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78 previousRow = xrange(len(string2) + 1) |
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79 for i, c1 in enumerate(string1): |
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80 currentRow = [i + 1] |
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81 for j, c2 in enumerate(string2): |
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82 insertions = previousRow[j + 1] + 1 |
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83 deletions = currentRow[j] + 1 |
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84 substitutions = previousRow[j] + (c1 != c2) |
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85 currentRow.append(min(insertions, deletions, substitutions)) |
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86 previousRow = currentRow |
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87 return previousRow[-1] |
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88 |
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89 |
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90 def getMinAvgMedMax(values): |
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91 """ |
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92 Get some stats about a dict |
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93 @param values: a distribution (the value being the number of occurrences of the key) |
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94 @type values: dict int to int |
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95 @return: a tuple |
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96 """ |
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97 minValues = min(values.keys()) |
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98 maxValues = max(values.keys()) |
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99 sumValues = sum([value * values[value] for value in values]) |
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100 nbValues = sum(values.values()) |
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101 allValues = [] |
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102 for key in values: |
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103 for i in range(values[key]): |
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104 allValues.append(key) |
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105 sortedValues = sorted(allValues) |
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106 sorted(values.values()) |
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107 if (nbValues % 2 == 0): |
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108 medValues = (sortedValues[nbValues / 2 - 1] + sortedValues[nbValues / 2]) / 2.0 |
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109 else: |
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110 medValues = sortedValues[(nbValues + 1) / 2 - 1] |
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111 return (minValues, float(sumValues) / nbValues, medValues, maxValues) |
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112 |
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113 |
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114 def xor(value1, value2): |
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115 """ |
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116 Logical xor |
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117 @param value1: a value |
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118 @type value1: anything |
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119 @param value2: a value |
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120 @type value2: anything |
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121 """ |
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122 return bool(value1) != bool(value2) |
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123 |
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124 |
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125 def diff(fileName1, fileName2): |
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126 """ |
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127 Compare two files |
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128 @param fileName1: a file name |
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129 @type fileName1: string |
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130 @param fileName2: another file name |
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131 @type fileName2: string |
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132 @return: None if the files are the same, a string otherwise |
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133 """ |
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134 handle1 = open(fileName1) |
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135 lines1 = handle1.readlines() |
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136 handle2 = open(fileName2) |
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137 lines2 = handle2.readlines() |
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138 if len(lines1) != len(lines2): |
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139 print "Sizes of files differ (%d != %d)" % (len(lines1), len(lines2)) |
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140 return False |
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141 for i in xrange(len(lines1)): |
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142 if lines1[i] != lines2[i]: |
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143 print "Line %d differ ('%s' != '%s')" % (i, lines1[i].strip(), lines2[i].strip()) |
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144 return False |
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145 return True |
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146 |
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147 |
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148 def binomialCoefficient(a, b): |
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149 """ |
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150 Compute cumulated product from a to b |
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151 @param a: a value |
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152 @type a: int |
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153 @param b: a value |
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154 @type b: int |
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155 """ |
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156 if a > b / 2: |
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157 a = b-a |
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158 p = 1.0 |
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159 for i in range(b-a+1, b+1): |
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160 p *= i |
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161 q = 1.0 |
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162 for i in range(1, a+1): |
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163 q *= i |
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164 return p / q |
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165 |
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166 |
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167 memory = {} |
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168 |
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169 # def fisherExactPValue(a, b, c, d): |
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170 # """ |
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171 # P-value of Fisher exact test for 2x2 contingency table |
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172 # """ |
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173 # if (a, b, c, d) in memory: |
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174 # return memory[(a, b, c, d)] |
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175 |
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176 # n = a + b + c + d |
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177 # i1 = binomialCoefficient(a, a+b) |
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178 # i2 = binomialCoefficient(c, a+c) |
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179 # i3 = binomialCoefficient(c+d, n) |
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180 # pValue = i1 * i2 / i3 |
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181 |
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182 # memory[(a, b, c, d)] = pValue |
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183 |
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184 # return pValue |
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185 |
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186 |
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187 def fisherExactPValue(a, b, c, d): |
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188 if (a, b, c, d) in memory: |
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189 return memory[(a, b, c, d)] |
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190 |
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191 scriptFileName = "tmpScript-%d.R" % (random.randint(0, 10000)) |
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192 rScript = open(scriptFileName, "w") |
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193 rScript.write("data = matrix(c(%d, %d, %d, %d), nr=2)\n" % (a, b, c, d)) |
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194 rScript.write("fisher.test(data)\n") |
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195 #rScript.write("chisq.test(data)\n") |
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196 rScript.close() |
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197 |
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198 rCommand = "R" |
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199 if "SMARTRPATH" in os.environ: |
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200 rCommand = os.environ["SMARTRPATH"] |
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201 command = "\"%s\" CMD BATCH %s" % (rCommand, scriptFileName) |
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202 status = subprocess.call(command, shell=True) |
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203 |
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204 if status != 0: |
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205 sys.exit("Problem with the execution of script file %s, status is: %s" % (scriptFileName, status)) |
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206 |
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207 outputRFileName = "%sout" % (scriptFileName) |
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208 outputRFile = open(outputRFileName) |
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209 pValue = None |
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210 pValueTag = "p-value " |
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211 for line in outputRFile: |
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212 line = line.strip() |
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213 if line == "": continue |
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214 for splittedLine in line.split(","): |
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215 splittedLine = splittedLine.strip() |
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216 if splittedLine.startswith(pValueTag): |
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217 pValue = float(splittedLine.split()[-1]) |
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218 break |
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219 |
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220 if pValue == None: |
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221 sys.exit("Problem with the cannot find p-value! File %s, values are: %d, %d, %d, %d" % (scriptFileName, a, b, c, d)) |
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222 |
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223 os.remove(scriptFileName) |
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224 os.remove(outputRFileName) |
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225 |
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226 memory[(a, b, c, d)] = pValue |
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227 |
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228 return pValue |
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229 |
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230 |
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231 def fisherExactPValueBulk(list): |
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232 |
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233 scriptFileName = "tmpScript-%d.R" % (random.randint(0, 10000)) |
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234 rScript = open(scriptFileName, "w") |
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Uploaded S-MART tool. A toolbox manages RNA-Seq and ChIP-Seq data.
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235 for element in list: |
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236 rScript.write("fisher.test(matrix(c(%d, %d, %d, %d), nr=2))$p.value\n" % (int(element[0]), int(element[1]), int(element[2]), int(element[3]))) |
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237 rScript.close() |
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238 |
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239 rCommand = "R" |
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240 if "SMARTRPATH" in os.environ: |
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241 rCommand = os.environ["SMARTRPATH"] |
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242 command = "\"%s\" CMD BATCH %s" % (rCommand, scriptFileName) |
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243 status = subprocess.call(command, shell=True) |
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244 |
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245 if status != 0: |
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246 sys.exit("Problem with the execution of script file %s, status is: %s" % (scriptFileName, status)) |
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247 |
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248 outputRFileName = "%sout" % (scriptFileName) |
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249 outputRFile = open(outputRFileName) |
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250 pValue = None |
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251 pValueTag = "[1] " |
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252 results = {} |
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253 cpt = 0 |
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254 for line in outputRFile: |
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255 line = line.strip() |
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256 if line == "": continue |
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257 if line.startswith(pValueTag): |
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258 pValue = float(line.split()[-1]) |
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259 results[list[cpt][0:2]] = pValue |
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260 cpt += 1 |
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261 |
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262 if pValue == None: |
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263 sys.exit("Problem with the cannot find p-value!") |
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264 if cpt != len(list): |
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265 sys.exit("Error in the number of p-values computed by R in file '%s'!" % (scriptFileName)) |
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266 |
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267 os.remove(scriptFileName) |
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268 os.remove(outputRFileName) |
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269 |
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270 return results |
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271 |