diff SMART/Java/Python/GetIntersection.py @ 38:2c0c0a89fad7

Uploaded

--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/SMART/Java/Python/GetIntersection.py	Thu May 02 09:56:47 2013 -0400
@@ -0,0 +1,164 @@
+#! /usr/bin/env python
+#
+# Copyright INRA-URGI 2009-2011
+# 
+# This software is governed by the CeCILL license under French law and
+# abiding by the rules of distribution of free software. You can use,
+# modify and/ or redistribute the software under the terms of the CeCILL
+# license as circulated by CEA, CNRS and INRIA at the following URL
+# "http://www.cecill.info".
+# 
+# As a counterpart to the access to the source code and rights to copy,
+# modify and redistribute granted by the license, users are provided only
+# with a limited warranty and the software's author, the holder of the
+# economic rights, and the successive licensors have only limited
+# liability.
+# 
+# In this respect, the user's attention is drawn to the risks associated
+# with loading, using, modifying and/or developing or reproducing the
+# software by the user in light of its specific status of free software,
+# that may mean that it is complicated to manipulate, and that also
+# therefore means that it is reserved for developers and experienced
+# professionals having in-depth computer knowledge. Users are therefore
+# encouraged to load and test the software's suitability as regards their
+# requirements in conditions enabling the security of their systems and/or
+# data to be ensured and, more generally, to use and operate it in the
+# same conditions as regards security.
+# 
+# The fact that you are presently reading this means that you have had
+# knowledge of the CeCILL license and that you accept its terms.
+#
+from optparse import OptionParser
+from commons.core.parsing.ParserChooser import ParserChooser
+from commons.core.writer.TranscriptWriter import TranscriptWriter
+from SMART.Java.Python.structure.Interval import Interval
+from SMART.Java.Python.structure.Transcript import Transcript
+from SMART.Java.Python.structure.Mapping import Mapping
+from SMART.Java.Python.misc.Progress import Progress
+from SMART.Java.Python.misc.UnlimitedProgress import UnlimitedProgress
+
+MINBIN = 3
+MAXBIN = 7
+REFERENCE = 0
+QUERY = 1
+
+def getBin(start, end):
+	for i in range(MINBIN, MAXBIN + 1):
+		binLevel = 10 ** i
+		if int(start / binLevel) == int(end / binLevel):
+			return int(i * 10 ** (MAXBIN + 1) + int(start / binLevel))
+	return int((MAXBIN + 1) * 10 ** (MAXBIN + 1))
+
+def getOverlappingBins(start, end):
+	array	= []
+	bigBin = int((MAXBIN + 1) * 10 ** (MAXBIN + 1))
+	for i in range(MINBIN, MAXBIN + 1):
+		binLevel = 10 ** i
+		array.append((int(i * 10 ** (MAXBIN + 1) + int(start / binLevel)), int(i * 10 ** (MAXBIN + 1) + int(end / binLevel))))
+	array.append((bigBin, bigBin))
+	return array
+
+
+class GetIntersection(object):
+
+	def __init__(self, verbosity):
+		self.verbosity              = verbosity
+		self.nbQueries              = 0
+		self.nbRefs	                = 0
+		self.nbWritten              = 0
+		self.bins	                = {}
+
+	def setReferenceFile(self, fileName, format):
+		chooser = ParserChooser(self.verbosity)
+		chooser.findFormat(format)
+		self.refParser = chooser.getParser(fileName)
+
+	def setQueryFile(self, fileName, format):
+		chooser = ParserChooser(self.verbosity)
+		chooser.findFormat(format)
+		self.queryParser = chooser.getParser(fileName)
+
+	def setOutputFile(self, fileName):
+		self.writer = TranscriptWriter(fileName, "gff3", self.verbosity)
+
+	def loadRef(self):
+		progress = UnlimitedProgress(10000, "Reading references", self.verbosity)
+		for transcript in self.refParser.getIterator():
+			if transcript.__class__.__name__ == "Mapping":
+				transcript = transcript.getTranscript()
+			chromosome = transcript.getChromosome()
+			bin		   = getBin(transcript.getStart(), transcript.getEnd())
+			if chromosome not in self.bins:
+				self.bins[chromosome] = {}
+			if bin not in self.bins[chromosome]:
+				self.bins[chromosome][bin] = []
+			self.bins[chromosome][bin].append(transcript)
+			self.nbRefs += 1
+			progress.inc()
+		progress.done()
+
+	def _compareTranscript(self, queryTranscript):
+		queryChromosome = queryTranscript.getChromosome()
+		if queryChromosome not in self.bins:
+			return None
+		queryStart = queryTranscript.getStart()
+		queryEnd   = queryTranscript.getEnd()
+		bins	   = getOverlappingBins(queryStart, queryEnd)
+		overlaps   = []
+		for binRange in bins:
+			for bin in range(binRange[0], binRange[1]+1):
+				if bin not in self.bins[queryChromosome]:
+					continue
+				for refTranscript in self.bins[queryChromosome][bin]:
+					newTranscript = queryTranscript.getIntersection(refTranscript)
+					if newTranscript != None:
+						overlaps.append(newTranscript)
+		if not overlaps:
+			return None
+		newTranscript = overlaps[0]
+		for transcript in overlaps[1:]:
+			newTranscript.merge(transcript)
+		return newTranscript
+
+	def compare(self):
+		progress = UnlimitedProgress(10000, "Comparing queries", self.verbosity)
+		for queryTranscript in self.queryParser.getIterator():
+			if queryTranscript.__class__.__name__ == "Mapping":
+				queryTranscript = queryTranscript.getTranscript()
+			progress.inc()
+			self.nbQueries += 1
+			newTranscript = self._compareTranscript(queryTranscript)
+			if newTranscript != None:
+				self.writer.addTranscript(queryTranscript)
+				self.nbWritten += 1
+		progress.done()
+		self.writer.close()
+
+	def displayResults(self):
+		print "# queries:  %d" % (self.nbQueries)
+		print "# refs:     %d" % (self.nbRefs)
+		print "# written:  %d" % (self.nbWritten)
+
+	def run(self):
+		self.loadRef()
+		self.compare()
+		self.displayResults()
+
+if __name__ == "__main__":
+	
+	description = "Get Intersection v1.0.0: Shrink the first data set so that all bases covered by the first data set is also covered by the second data set. [Category: Data Comparison]"
+
+	parser = OptionParser(description = description)
+	parser.add_option("-i", "--input1",	        dest="inputFileName1", action="store",			           type="string", help="query input file [compulsory] [format: file in transcript format given by -f]")
+	parser.add_option("-f", "--format1",        dest="format1",		  action="store",			           type="string", help="format of previous file [compulsory] [format: transcript file format]")
+	parser.add_option("-j", "--input2",	        dest="inputFileName2", action="store",			           type="string", help="reference input file [compulsory] [format: file in transcript format given by -g]")
+	parser.add_option("-g", "--format2",        dest="format2",		  action="store",			           type="string", help="format of previous file [compulsory] [format: transcript file format]")
+	parser.add_option("-o", "--output",	        dest="outputFileName", action="store",			           type="string", help="output file [format: output file in GFF3 format]")
+	parser.add_option("-v", "--verbosity",      dest="verbosity",	   action="store",      default=1,     type="int",	 help="trace level [format: int]")
+	(options, args) = parser.parse_args()
+
+	gi = GetIntersection(options.verbosity)
+	gi.setQueryFile(options.inputFileName1, options.format1)
+	gi.setReferenceFile(options.inputFileName2, options.format2)
+	gi.setOutputFile(options.outputFileName)
+	gi.run()