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NCBI BLAST+ makeprofiledb (version 2.16.0+galaxy0)
One or NCBI PSSM ASN.1 format scoremat files (often named *.smp)
This is the database name shown in BLAST search output
Exclude domains that do not pass validation test
Exclude domains with with maximum number of independent observations below this threshold

What it does

Make a protein domain profile database (for use with RPS-BLAST or RSP-TBLASTN) from one or more Position Specific Scoring Matrices (PSSM) files in the NCBI "scoremat" ASN.1 format (usually named *.smp).

This is a wrapper for the NCBI BLAST+ tool 'makeprofiledb'.

More information about makeprofiledb can be found in the BLAST Command Line Applications User Manual.