What it does

Given several Rdata object this tool run a meta-analysis using the metaMA R package.

Results

• Venn Diagram or upsetR diagram (when the number of studies is greater than 2) summarizing the results of the meta-analysis

• A list of indicators to evaluate the quality of the performance of the meta-analysis

  • DE : Number of differentially expressed genes
  • IDD (Integration Driven discoveries) : number of genes that are declared differentially expressed in the meta-analysis that were not identified in any of the single studies alone
  • Loss : Number of genes that are identified differentially expressed in single studies but not in meta-analysis
  • DR (Integration-driven Discovery Rate) : corresponding proportion of IDD
  • IRR (Integration-driven Revision) : corresponding proportion of Loss

• Fully sortable and requestable table, with gene annotations and hypertext links to NCBI gene database.