chicViewpointBackgroundModel (version 3.6+galaxy1)

chicViewpointBackgroundModel computes for all given samples with all reference points a background model. For all relative distances to a reference point a negative binomial distribution is fitted. Moreover, for each relative distance to a reference point the average value for this location is computed. Both background models are used, the first one for p-value and significance computation, the second one to filter out interactions with a less x-fold over mean.

The background distributions are fixed at --fixateRange i.e. all distances lower / higher than this value use the fixed background distribution.

For more information about HiCExplorer please consider our documentation on readthedocs.io