Dataset formats

The input dataset is tabular with a column of identifiers. The output dataset is html with a link to g:Profiler. (Dataset missing?)

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What it does

This tool creates a link to the g:GOSt tool (Gene Group Functional Profiling), which is part of the g:Profiler site at the University of Tartu in Estonia. g:GOSt retrieves the most significant Gene Ontology (GO) terms, KEGG and REACTOME pathways, and TRANSFAC motifs for a user-specified group of genes, proteins, or microarray probes. g:GOSt also allows analysis of ranked or ordered lists of genes, visual browsing of GO graph structure, interactive visualization of retrieved results, and many other features. Multiple testing corrections are applied to extract only statistically important results.

The g:GOSt form is pre-filled with gene, protein, or microarray probe IDs from the selected column of a tabular Galaxy dataset. Or you can chose to use the genomic coordinates (must be lastest build used by Ensembl). The coordinates don't have to be genes they can be for SNPs, and g:GOst will map to the gene ID. To follow the created link, click on the eye icon when the Galaxy tool has finished running. Once at the g:Profiler site, scroll down to see the g:GOSt results. You can also adjust the options in the g:GOSt form to your liking, or use the row of links between the form and the results to run other g:Profiler tools using the same list of IDs.

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Reference

Reimand J, Kull M, Peterson H, Hansen J, Vilo J. (2007) g:Profiler -- a web-based toolset for functional profiling of gene lists from large-scale experiments. Nucleic Acids Res. 35(Web Server issue):W193-200. Epub 2007 May 3.