Galaxy |

GEMINI interactions (version 0.10.1.0)

GEMINI database:

Only files with version 0.10.1 are accepted.

Studying:

Specify gene name:

e.g. PTPN22 (-g)

Choose a gemini annotation database:

Set filter for Breadth-first search (BFS) in the Protein-Protein Interaction network:

(-r)

Returns variant info (e.g. impact, biotype) for interacting genes:

(--var)

What it does

Integrating the knowledge of the known protein-protein interactions would be useful in explaining variation data. Meaning to say that a damaging variant in an interacting partner of a potential protein may be equally interesting as the protein itself. We have used the HPRD binary interaction data to build a p-p network graph which can be explored by GEMINI.

Citation

If you use GEMINI in your research, please cite the following manuscript: